cocaine and baclofen

cocaine has been researched along with baclofen in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.45)	18.7374
1990's	7 (10.14)	18.2507
2000's	30 (43.48)	29.6817
2010's	29 (42.03)	24.3611
2020's	2 (2.90)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Kalivas, PW; Steketee, JD	1
Andrews, MM; Roberts, DC; Vickers, GJ	1
Andrews, MM; Roberts, DC	1
Ling, W; Majewska, D; Shoptaw, S	1
Gong, W; Justice, JB; Neill, DB	1
Beyer, CE; Goldberg, SR; Schindler, CW; Shoaib, M; Swanner, LS	1
Campbell, UC; Carroll, ME; Lac, ST	1
Brebner, K; Phelan, R; Roberts, DC	2
Brebner, K; Roberts, DC	1
Druhan, JP; Franklin, TR	1
Goldberg, SR; Kutkat, SW; Miller, CR; Munzar, P	1
Lucki, I; McGonigle, P; Stanwood, GD	1
Kushner, SA; Unterwald, EM	1
Campbell, UC; Carroll, ME; Morgan, AD	1
Di Ciano, P; Everitt, BJ	2
Hotsenpiller, G; Wolf, ME	1
Collu, M; Fadda, P; Fratta, W; Fresu, A; Scherma, M	1
Allen, TS; Glaser, PE; Hays, LR; Lile, JA; Rush, CR; Stoops, WW	1
Charuvastra, VC; Hsieh, YC; Kintaudi, PC; Ling, W; Rotheram-Fuller, EJ; Shoptaw, S; Yang, X	1
Gasior, M; Kaminski, R; Witkin, JM	1
Evans, KA; Fuchs, RA; Parker, MP; See, RE	1
Jayaram, P; Steketee, JD	1
Febo, M; Segarra, AC	1
Beyer, CE; Steketee, JD	1
Cryan, JF; Froestl, W; Markou, A; Slattery, DA	1
Froestl, W; Griffiths, RR; Weerts, EM	1
Foltin, RW; Haney, M; Hart, CL	1
Cryan, JF; Kaupmann, K; Lhuillier, L; Mombereau, C	1
Filip, M; Frankowska, M	1
Filip, M; Frankowska, M; Przegaliński, E	1
Maher, BJ; Westbrook, GL	1
Bossert, JM; Hope, BT; Koya, E; Shaham, Y; Uejima, JL; Wihbey, KA	1
Bell, GH; Fuchs, RA; Ramirez, DR	1
Alathari, H; Beresford, T; Biswas, K; Chiang, N; Childress, AR; Collins, J; Elkashef, A; Fudala, PJ; Gorgon, L; Gruber, V; Kahn, R; Li, SH; Liberto, J; McSherry, F; Montoya, I; Shoptaw, S; Stock, C; Wallace, C; Watson, D	1
Fuchs, RA; Lasseter, HC; Ramirez, DR; Xie, X	1
Kalivas, PW; LaLumiere, RT; Niehoff, KE	1
Buffalari, DM; See, RE	1
Oleson, EB; Richardson, JM; Roberts, DC	1
Halbout, B; Heidbreder, CA; Hutcheson, DM; Quarta, D; Valerio, E	1
Alvarez, VA; Bello, EP; Gelman, DM; Lovinger, DM; Low, MJ; Mateo, Y; Noaín, D; Rubinstein, M; Shin, JH	1
Carroll, ME; Holtz, NA	1
Aston-Jones, GS; Sartor, GC	1
Everitt, BJ; Jonkman, S; Pelloux, Y	1
Deadwyler, SA; Hampson, RE; Opris, I; Porrino, LJ	1
Aston-Jones, G; Sartor, GC	1
Arguello, AA; Blanton, MA; Fuchs, RA; Lasseter, HC; Reittinger, AM; Wells, AM; Xie, X	1
Cheng, K; Koek, W; Rice, KC	1
Gordon, J; Taylor, JR; Torregrossa, MM	1
Borgland, SL; Pitman, KA; Puil, E	1
Broekhoven, MH; Damsteegt, R; Limpens, JH; Vanderschuren, LJ; Voorn, P	1
Cosme, CV; Gutman, AL; LaLumiere, RT	1
Brebner, K; Cunningham, JJ; Lothian, BC; Morgen, J; Orr, E	1
Martin-Fardon, R; Matzeu, A; Weiss, F	1
Baker, DA; Blacktop, JM; Mantsch, JR; Mayer, M; Van Hoof, M; Vranjkovic, O	1
Castagné, V; Froger-Colléaux, C	1
Allen, AG; DePoy, LM; Gourley, SL	1
Hwang, EK; Lupica, CR; Zapata, A	1
Chang, S; Choi, KH; Gwak, YS; Jang, EY; Jin, W; Kim, HY; Kim, JH; Kim, MS; Koo, H; Lee, BH; Lee, JG; Lee, JY; Ryu, YH; Steffensen, SC; Yang, CH; Yoon, SS	1
Arguello, AA; Fuchs, RA; Higginbotham, JA; Hodges, MA; Lyons, CM; Wang, R	1
Aston-Jones, G; McGlinchey, EM	1
Belozertseva, I; Bespalov, AY; Dravolina, OA; Spanagel, R; Takahashi, TT; Vengeliene, V; Zvartau, E	1
de Miguel, E; Hyytiä, P; Janhunen, SK; Kaskinoro, J; Korpi, ER; Kuokkanen, K; Lainiola, M; Linden, AM; Myllymäki, M; Paasikoski, N; Vekovischeva, O; Vesajoki, M	1
Filion, MP; Minogianis, EA; Samaha, AN; Servonnet, A	1
Frankowska, M; Gamberini, S; Gawlińska, K; Gawliński, D; Jastrzębska, J; Pieniążek, R; Suder, A; Wydra, K	1
Sun, W; Yuill, MB	1

Reviews

1 review(s) available for cocaine and baclofen

Article	Year
GABA modulation of cocaine self-administration. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Animals; Baclofen; Cocaine; Conditioning, Psychological; gamma-Aminobutyric Acid; Organophosphonates; Phosphinic Acids; Reinforcement, Psychology; Self Administration	2000

Trials

3 trial(s) available for cocaine and baclofen

Article	Year
Baclofen as a cocaine anti-craving medication: a preliminary clinical study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:5 Topics: Adult; Baclofen; Cocaine; Female; GABA Agonists; Humans; Male; Middle Aged; Opioid-Related Disorders	1998
Baclofen does not alter the reinforcing, subject-rated or cardiovascular effects of intranasal cocaine in humans. Psychopharmacology, 2004, Volume: 171, Issue:4 Topics: Administration, Intranasal; Adult; Analysis of Variance; Baclofen; Behavior, Addictive; Cardiovascular Physiological Phenomena; Cocaine; Double-Blind Method; Female; Humans; Male; Middle Aged; Reinforcement, Psychology	2004
Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine use. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:12 Topics: Adult; Baclofen; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; GABA Agonists; Humans; Longitudinal Studies; Male; Middle Aged; Substance Abuse Detection; Treatment Outcome	2003

Other Studies

65 other study(ies) available for cocaine and baclofen

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Sensitization to psychostimulants and stress after injection of pertussis toxin into the A10 dopamine region. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Adenosine Diphosphate; Animals; Baclofen; Behavior, Animal; Brain; Caffeine; Cerebral Cortex; Cocaine; Dialysis; Dopamine; GTP-Binding Proteins; Male; Motor Activity; Nucleus Accumbens; Pertussis Toxin; Rats; Rats, Inbred Strains; Stress, Physiological; Virulence Factors, Bordetella	1991
Baclofen attenuates the reinforcing effects of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:4 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Wistar; Self Administration	1996
Baclofen suppression of cocaine self-administration: demonstration using a discrete trials procedure. Psychopharmacology, 1997, Volume: 131, Issue:3 Topics: Animals; Baclofen; Circadian Rhythm; Cocaine; Eating; GABA Agonists; Male; Rats; Rats, Wistar; Self Administration	1997
GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse (New York, N.Y.), 1998, Volume: 29, Issue:4 Topics: Animals; Baclofen; Cocaine; Dopamine; Dopamine Uptake Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Picrotoxin; Piperazines; Rats; Rats, Wistar	1998
The GABAB agonist baclofen modifies cocaine self-administration in rats. Behavioural pharmacology, 1998, Volume: 9, Issue:3 Topics: Animals; Baclofen; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Extinction, Psychological; Food; GABA Agonists; GABA-B Receptor Agonists; Injections; Male; Microinjections; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration	1998
Effects of baclofen on maintenance and reinstatement of intravenous cocaine self-administration in rats. Psychopharmacology, 1999, Volume: 143, Issue:2 Topics: Animals; Baclofen; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Injections, Intravenous; Male; Rats; Rats, Wistar; Self Administration	1999
Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules. Psychopharmacology, 2000, Volume: 148, Issue:3 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Dopamine; gamma-Aminobutyric Acid; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration	2000
Intra-VTA baclofen attenuates cocaine self-administration on a progressive ratio schedule of reinforcement. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4 Topics: Animals; Baclofen; Cocaine; Conditioning, Operant; Food; GABA Agonists; Male; Microinjections; Neostriatum; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, GABA-B; Reinforcement Schedule; Self Administration; Ventral Tegmental Area	2000
Involvement of the nucleus accumbens and medial prefrontal cortex in the expression of conditioned hyperactivity to a cocaine-associated environment in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:6 Topics: Amygdala; Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Male; Muscimol; Neural Inhibition; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B	2000
Failure of baclofen to modulate discriminative-stimulus effects of cocaine or methamphetamine in rats. European journal of pharmacology, 2000, Nov-17, Volume: 408, Issue:2 Topics: Animals; Baclofen; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Male; Methamphetamine; Rats; Rats, Sprague-Dawley	2000
Differential regulation of dopamine D2 and D3 receptors by chronic drug treatments. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3 Topics: Animals; Autoradiography; Baclofen; Cocaine; Male; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reserpine; Tetrahydronaphthalenes	2000
Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding. Life sciences, 2001, Jul-20, Volume: 69, Issue:9 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Dopamine; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Guanosine 5'-O-(3-Thiotriphosphate); Limbic System; Male; Rats; Rats, Inbred F344; Receptors, GABA-B; Subcellular Fractions; Substantia Nigra; Sulfur Radioisotopes; Synaptic Membranes; Ventral Tegmental Area	2001
Sex differences in the effects of baclofen on the acquisition of intravenous cocaine self-administration in rats. Drug and alcohol dependence, 2002, Mar-01, Volume: 66, Issue:1 Topics: Animals; Baclofen; Cocaine; Dopamine Uptake Inhibitors; Female; GABA Agonists; Infusions, Intravenous; Male; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology; Self Administration; Sex Characteristics	2002
The GABA(B) receptor agonist baclofen attenuates cocaine- and heroin-seeking behavior by rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Baclofen; Behavior, Addictive; Cocaine; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Agonists; Heroin; Male; Rats; Receptors, GABA-B; Self Administration	2003
Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens. Neuroscience, 2003, Volume: 118, Issue:1 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward; Substance Withdrawal Syndrome; Synaptic Transmission	2003
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat. Synapse (New York, N.Y.), 2003, Volume: 50, Issue:1 Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Agonists; GABA-B Receptor Agonists; Male; Microdialysis; Morphine; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Receptors, GABA-B; Reward; Substance-Related Disorders; Synaptic Transmission; Up-Regulation	2003
Pharmacological modulation of GABA(B) receptors affects cocaine-induced seizures in mice. Psychopharmacology, 2004, Volume: 174, Issue:2 Topics: Animals; Baclofen; Cocaine; Dopamine Uptake Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Kindling, Neurologic; Male; Mice; Piperazines; Receptors, GABA-A; Receptors, GABA-B; Seizures	2004
Contribution of the ventral tegmental area to cocaine-seeking maintained by a drug-paired conditioned stimulus in rats. The European journal of neuroscience, 2004, Volume: 19, Issue:6 Topics: Amygdala; Analysis of Variance; Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; Muscimol; Nucleus Accumbens; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Ventral Tegmental Area	2004
Differential involvement of orbitofrontal cortex subregions in conditioned cue-induced and cocaine-primed reinstatement of cocaine seeking in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-21, Volume: 24, Issue:29 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Extinction, Psychological; Frontal Lobe; Infusions, Intravenous; Male; Motor Activity; Muscimol; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration	2004
Effects of repeated cocaine on medial prefrontal cortical GABAB receptor modulation of neurotransmission in the mesocorticolimbic dopamine system. Journal of neurochemistry, 2004, Volume: 90, Issue:4 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Rats; Receptors, GABA-B; Synaptic Transmission; Ventral Tegmental Area	2004
Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen. Synapse (New York, N.Y.), 2004, Volume: 54, Issue:1 Topics: Animals; Autoradiography; Baclofen; Cocaine; Dopamine Uptake Inhibitors; Entorhinal Cortex; Enzyme Activation; Estrogens; Female; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ovariectomy; Rats; Receptors, GABA-B; Ventral Tegmental Area	2004
Injections of baclofen into the ventral medial prefrontal cortex block the initiation, but not the expression, of cocaine sensitization in rats. Psychopharmacology, 2005, Volume: 180, Issue:2 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-B	2005
The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:11 Topics: Analysis of Variance; Anesthetics, Local; Animals; Baclofen; Behavior, Animal; Cocaine; Cyclopentanes; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation	2005
Effects of GABAergic modulators on food and cocaine self-administration in baboons. Drug and alcohol dependence, 2005, Dec-12, Volume: 80, Issue:3 Topics: Alprazolam; Animals; Baclofen; Cocaine; Dopamine; Feeding Behavior; GABA Agonists; GABA Modulators; Injections, Intravenous; Male; Nipecotic Acids; Papio anubis; Reinforcement, Psychology; Self Administration; Tiagabine	2005
Effects of baclofen on cocaine self-administration: opioid- and nonopioid-dependent volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:8 Topics: Adult; Baclofen; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Opioid-Related Disorders; Self Administration	2006
GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2 Topics: Animals; Baclofen; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclopentanes; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Pyrimidines; Receptors, GABA-B; Signal Transduction; Synaptic Transmission	2007
Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses. European journal of pharmacology, 2007, Oct-01, Volume: 571, Issue:2-3 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Feeding Behavior; GABA Agonists; GABA Antagonists; Injections, Intravenous; Male; Morpholines; Organophosphorus Compounds; Phenols; Rats; Rats, Wistar; Receptors, GABA-B; Reinforcement, Psychology; Secondary Prevention; Self Administration	2007
Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination. European journal of pharmacology, 2007, Nov-28, Volume: 574, Issue:2-3 Topics: Animals; Baclofen; Cocaine; Discrimination Learning; GABA Modulators; Male; Morpholines; Motor Activity; Organophosphorus Compounds; Phenols; Rats; Rats, Wistar; Receptors, GABA-B; Self Administration	2007
Co-transmission of dopamine and GABA in periglomerular cells. Journal of neurophysiology, 2008, Volume: 99, Issue:3 Topics: Analysis of Variance; Animals; Animals, Newborn; Baclofen; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Inbred DBA; Mice, Transgenic; Olfactory Bulb; Olfactory Receptor Neurons; Sulpiride; Tyrosine 3-Monooxygenase	2008
Role of ventral medial prefrontal cortex in incubation of cocaine craving. Neuropharmacology, 2009, Volume: 56 Suppl 1 Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Bicuculline; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; GABA Agonists; GABA Antagonists; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Long-Evans; Self Administration; Sucrose; Sweetening Agents; Time Factors	2009
Nucleus accumbens shell and core involvement in drug context-induced reinstatement of cocaine seeking in rats. Psychopharmacology, 2008, Volume: 200, Issue:4 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Extinction, Psychological; GABA Agonists; Infusions, Intravenous; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration	2008
Multi-center trial of baclofen for abstinence initiation in severe cocaine-dependent individuals. Drug and alcohol dependence, 2009, Jul-01, Volume: 103, Issue:1-2 Topics: Adult; Baclofen; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Counseling; Dose-Response Relationship, Drug; Double-Blind Method; Educational Status; Employment; Female; GABA Agonists; Humans; Limbic System; Male; Middle Aged; Placebos; Racial Groups; Safety	2009
Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats. The European journal of neuroscience, 2009, Volume: 30, Issue:7 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Extinction, Psychological; Frontal Lobe; GABA Agonists; Male; Muscimol; Random Allocation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Ventral Tegmental Area	2009
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learning & memory (Cold Spring Harbor, N.Y.), 2010, Volume: 17, Issue:4 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Clenbuterol; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Extinction, Psychological; Food Deprivation; Frontal Lobe; GABA Agonists; GABA Antagonists; Male; Microinjections; Muscimol; Phenoxyacetates; Propanolamines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Time Factors	2010
Inactivation of the bed nucleus of the stria terminalis in an animal model of relapse: effects on conditioned cue-induced reinstatement and its enhancement by yohimbine. Psychopharmacology, 2011, Volume: 213, Issue:1 Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug Therapy, Combination; Extinction, Psychological; Male; Models, Animal; Muscimol; Rats; Rats, Sprague-Dawley; Secondary Prevention; Self Administration; Septal Nuclei; Yohimbine	2011
A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid. Psychopharmacology, 2011, Volume: 214, Issue:2 Topics: Analysis of Variance; Animals; Appetitive Behavior; Baclofen; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Consummatory Behavior; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluoxetine; GABA-B Receptor Agonists; Haloperidol; Infusions, Intravenous; Male; Models, Theoretical; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Self Administration; Time Factors	2011
The GABA-B positive modulator GS39783 decreases psychostimulant conditioned-reinforcement and conditioned-reward. Addiction biology, 2011, Volume: 16, Issue:3 Topics: Allosteric Regulation; Amphetamine; Animals; Association Learning; Baclofen; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Cyclopentanes; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Motivation; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, GABA-B; Reinforcement Schedule; Reward; Self Administration	2011
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nature neuroscience, 2011, Jul-10, Volume: 14, Issue:8 Topics: Analysis of Variance; Animals; Autoradiography; Baclofen; Choice Behavior; Cocaine; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Food; GABA-B Receptor Agonists; Hydrazines; Hyperkinesis; In Vitro Techniques; Maze Learning; Membrane Potentials; Mesencephalon; Mice; Mice, Knockout; Motivation; Motor Activity; Neurons; Quinpirole; Receptors, Dopamine D2; Reinforcement Schedule; Reward; Sulpiride	2011
Baclofen has opposite effects on escalation of cocaine self-administration: increased intake in rats selectively bred for high (HiS) saccharin intake and decreased intake in those selected for low (LoS) saccharin intake. Pharmacology, biochemistry, and behavior, 2011, Volume: 100, Issue:2 Topics: Animals; Baclofen; Cocaine; Female; GABA-B Receptor Agonists; Rats; Saccharin; Self Administration	2011
A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Mar-28, Volume: 32, Issue:13 Topics: Animals; Baclofen; Benzoxazoles; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Morpholinos; Muscimol; Naphthyridines; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neurons; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley; Septum of Brain; Urea	2012
Differential roles of the dorsolateral and midlateral striatum in punished cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Mar-28, Volume: 32, Issue:13 Topics: Animals; Animals, Outbred Strains; Baclofen; Cocaine; Conditioning, Operant; Corpus Striatum; Drug-Seeking Behavior; Electric Stimulation; GABA Agonists; Male; Microinjections; Muscimol; Punishment; Rats; Self Administration	2012
Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen. Psychopharmacology, 2013, Volume: 225, Issue:1 Topics: Animals; Baclofen; Brain; Cocaine; Cognition; Cognition Disorders; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; GABA-B Receptor Agonists; Injections, Intravenous; Macaca mulatta; Male; Positron-Emission Tomography; Prefrontal Cortex; Radiopharmaceuticals	2013
Regulation of the ventral tegmental area by the bed nucleus of the stria terminalis is required for expression of cocaine preference. The European journal of neuroscience, 2012, Volume: 36, Issue:11 Topics: Animals; Baclofen; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; GABA-B Receptor Agonists; Male; Muscimol; Neuronal Tract-Tracers; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Septal Nuclei; Ventral Tegmental Area	2012
Extracellular signal-regulated kinase in the basolateral amygdala, but not the nucleus accumbens core, is critical for context-response-cocaine memory reconsolidation in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:5 Topics: Amygdala; Animals; Baclofen; Butadienes; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; GABA-B Receptor Agonists; Male; Memory; Muscimol; Nitriles; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Signal Transduction	2013
Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse. The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:3 Topics: Animals; Baclofen; Benzodiazepines; Benzofurans; Cocaine; Columbidae; Diazepam; Discrimination, Psychological; Ethanol; GABA-B Receptor Agonists; Illicit Drugs; Nicotine; Organophosphorus Compounds; Phenols; Sodium Oxybate	2013
Double dissociation between the anterior cingulate cortex and nucleus accumbens core in encoding the context versus the content of pavlovian cocaine cue extinction. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-08, Volume: 33, Issue:19 Topics: Analysis of Variance; Animals; Baclofen; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; GABA-A Receptor Agonists; Gyrus Cinguli; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Valine	2013
GABA(B) modulation of dopamine release in the nucleus accumbens core. The European journal of neuroscience, 2014, Volume: 40, Issue:10 Topics: Animals; Baclofen; Benzylamines; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Mice, Inbred C57BL; Motor Activity; Neurons; Nicotinic Antagonists; Nucleus Accumbens; Phosphinic Acids; Quinpirole; Receptors, Dopamine D2; Receptors, GABA-B; Tissue Culture Techniques	2014
Pharmacological inactivation of the prelimbic cortex emulates compulsive reward seeking in rats. Brain research, 2015, Dec-02, Volume: 1628, Issue:Pt A Topics: Animals; Baclofen; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Decision Making; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Executive Function; GABA Agonists; Goals; Impulsive Behavior; Male; Muscimol; Rats, Wistar; Reward	2015
The Dorsal Agranular Insular Cortex Regulates the Cued Reinstatement of Cocaine-Seeking, but not Food-Seeking, Behavior in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:10 Topics: Analysis of Variance; Animals; Baclofen; Cerebral Cortex; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Food; GABA Agonists; Male; Microinjections; Muscimol; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration	2015
Effects of fendiline on cocaine-seeking behavior in the rat. Psychopharmacology, 2015, Volume: 232, Issue:24 Topics: Animals; Baclofen; Behavior, Addictive; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, Psychological; Fendiline; Male; Motor Activity; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration	2015
Transient inactivation of the posterior paraventricular nucleus of the thalamus blocks cocaine-seeking behavior. Neuroscience letters, 2015, Nov-03, Volume: 608 Topics: Animals; Baclofen; Cocaine; Conditioning, Psychological; Cues; Discrimination, Psychological; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats, Wistar; Reward; Self Administration	2015
Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats. Neuropharmacology, 2016, Volume: 102 Topics: Animals; Baclofen; Bicuculline; Cocaine; Corticotropin-Releasing Hormone; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area	2016
Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat. European journal of pharmacology, 2016, Apr-15, Volume: 777 Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Motivation; Raclopride; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration	2016
Adolescent cocaine self-administration induces habit behavior in adulthood: sex differences and structural consequences. Translational psychiatry, 2016, 08-30, Volume: 6, Issue:8 Topics: Age Factors; Animals; Baclofen; Behavior, Animal; Cocaine; Conditioning, Psychological; Decision Making; Dendritic Spines; Dopamine Uptake Inhibitors; Female; Flavones; GABA-B Receptor Agonists; Male; Mice; Prefrontal Cortex; Receptor, trkB; Reward; Self Administration	2016
Lateral Habenula Involvement in Impulsive Cocaine Seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:5 Topics: Animals; Baclofen; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Electroshock; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Habenula; Impulsive Behavior; Male; Motivation; Muscarinic Agonists; Muscimol; Punishment; Rats, Long-Evans; Receptors, GABA; Receptors, Muscarinic; Reinforcement, Psychology; Self Administration	2017
Acupuncture reduces relapse to cocaine-seeking behavior via activation of GABA neurons in the ventral tegmental area. Addiction biology, 2018, Volume: 23, Issue:1 Topics: Acupuncture; Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophysiological Phenomena; GABA-B Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Locomotion; Microdialysis; Nucleus Accumbens; Rats; Ventral Tegmental Area	2018
Role of the agranular insular cortex in contextual control over cocaine-seeking behavior in rats. Psychopharmacology, 2017, Volume: 234, Issue:16 Topics: Animals; Baclofen; Cerebral Cortex; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug-Seeking Behavior; Extinction, Psychological; GABA Agonists; Male; Memory; Memory Consolidation; Muscimol; Rats; Rats, Sprague-Dawley; Self Administration	2017
Dorsal Hippocampus Drives Context-Induced Cocaine Seeking via Inputs to Lateral Septum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:5 Topics: Animals; Baclofen; Behavior, Addictive; Clozapine; Cocaine; Cues; Drug-Seeking Behavior; Extinction, Psychological; Hippocampus; Locomotion; Male; Microinjections; Muscimol; Neuroanatomical Tract-Tracing Techniques; Oncogene Proteins v-fos; Rats; Self Administration; Septal Nuclei	2018
Efficacy and side effects of baclofen and the novel GABA Psychopharmacology, 2018, Volume: 235, Issue:7 Topics: Alcoholism; Allosteric Regulation; Animals; Baclofen; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; GABA-B Receptor Agonists; Male; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-B; Self Administration; Treatment Outcome	2018
GABA Addiction biology, 2019, Volume: 24, Issue:6 Topics: Allosteric Regulation; Animals; Baclofen; Behavior, Animal; Benzofurans; Central Nervous System Depressants; CHO Cells; Cocaine; Cricetulus; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Ethanol; GABA Modulators; GABA-B Receptor Agonists; Humans; Mice; Neuronal Plasticity; Quinazolinones; Rats; Receptors, GABA-B; Receptors, Glutamate; Reward; Self Administration; Ventral Tegmental Area	2019
Role of the orbitofrontal cortex and the dorsal striatum in incentive motivation for cocaine. Behavioural brain research, 2019, 10-17, Volume: 372 Topics: Animals; Baclofen; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Drug-Seeking Behavior; Male; Motivation; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration	2019
The impact of GABA European journal of pharmacology, 2020, Sep-15, Volume: 883 Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Drug-Seeking Behavior; GABA-B Receptor Agonists; Male; Organophosphorus Compounds; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Reward	2020
Role of the GABA Psychopharmacology, 2020, Volume: 237, Issue:12 Topics: Animals; Baclofen; Behavior, Addictive; Central Amygdaloid Nucleus; Cocaine; Cocaine-Related Disorders; Compulsive Behavior; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Self Administration	2020