cocaine has been researched along with aspartic acid in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 14 (45.16) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Gilles, R; Schoffeniels, E | 3 |
| Ichishita, H; Odagiri, H; Shimizu, H | 1 |
| Guo, H; Kunko, PM; Mo, Q; Robinson, SE; Smith, JA | 1 |
| Kunko, PM; Maher, JR; Mo, Q; Robinson, SE; Smith, JA; Wallace, MJ | 1 |
| Chang, L; Ernst, T; Mehringer, CM; Strickland, T | 1 |
| Li, SJ; Pankiewicz, J; Stein, EA; Wang, Y | 1 |
| Barker, EL; Blakely, RD; Moore, KR; Rakhshan, F | 1 |
| Christensen, JD; Cohen, BM; Frederick, B; Kaufman, MJ; Lukas, SE; Mendelson, JH; Moore, CM; Renshaw, PF; Rose, SL | 1 |
| Chang, L; Ernst, T; Gilbride, K; Kuo, J; Poland, RE; Smith, LM; Walot, I; Yonekura, ML | 1 |
| Chen, N; Reith, ME; Vaughan, RA | 1 |
| Berfield, JL; Chen, N; Reith, ME; Rickey, J | 1 |
| Chen, N; Dutta, AK; Maiti, S; Reith, ME; Zhen, J | 1 |
| Bondi, CD; Kozikowski, AP; Kulkarni, SS; Newman, AH; Pan, S; Surratt, CK; Ukairo, OT | 1 |
| Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW | 1 |
| Arbabian, M; Chen, Y; Hajipour, AR; Ruoho, AE; Sievert, MK | 1 |
| Bolo, NR; Cowan, RL; Dietrich, M; Haga, E; Lukas, SE; Renshaw, PF | 1 |
| Ambrosio, E; Del Olmo, N; García-Lecumberri, C; Higuera-Matas, A; Miguéns, M; Torres, I | 1 |
| Ambrosio, E; Crespo, JA; Del Olmo, N; García-Lecumberri, C; Higuera-Matas, A; Miguéns, M; Montoya, GL | 1 |
| Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J | 1 |
| Castillo, MA; Nestler, EJ; Russo, SJ; Ulery-Reynolds, PG; Vialou, V | 1 |
| Licata, SC; Renshaw, PF | 1 |
| Ortinski, PI; Pierce, RC; Turner, JR | 1 |
| de Freitas, IG; de Melo Reis, RA; Dos Santos Pereira, M; Kubrusly, RC; Lowe, J; Manhães, AC; Martins, RS; Pecinalli, NR; Santos, LE; Sathler, MF; Stutz, B; Taveira-da-Silva, R | 1 |
| Williams, JT; Yorgason, JT; Zeppenfeld, DM | 1 |
| Chiu, AS; Gable, ES; Kim, J; Kippin, TE; Shin, CB; Szumlinski, KK; Templeton, TJ; Vieira, PA | 1 |
| Fu, Y; Liu, Y; Nie, J; Niu, Y; Yang, A; Yang, J; Zhang, H; Zhao, J | 1 |
| Aggelidou, E; Deda, O; Gika, H; Kritis, A; Krokos, A; Raikos, N; Theodoridis, G; Virgiliou, C | 1 |
| Adeyeye, EI; Aluko, AO; Asaolu, SS | 1 |
2 review(s) available for cocaine and aspartic acid
| Article | Year |
|---|---|
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic | 2006 |
Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction.
Topics: Alcoholism; Animals; Appetite Stimulants; Aspartic Acid; Brain; Choline; Cocaine; Creatine; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Marijuana Abuse; Neurochemistry; Opiate Alkaloids; Smoking; Substance-Related Disorders; Toluene | 2010 |
1 trial(s) available for cocaine and aspartic acid
| Article | Year |
|---|---|
Proton magnetic resonance spectroscopy of human basal ganglia: response to cocaine administration.
Topics: Adult; Aspartic Acid; Basal Ganglia; Caudate Nucleus; Choline; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Energy Metabolism; Humans; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Male; Putamen; Water-Electrolyte Balance | 2000 |
28 other study(ies) available for cocaine and aspartic acid
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Fixation of 14CO2 by amino acids in the ventral eerve chain of the crustacean Homarus vulgaris M. Edw].
Topics: Amino Acids; Ammonium Chloride; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chlorides; Citric Acid Cycle; Cocaine; Crustacea; Glutamates; Nervous System; Sulfates; Taurine; Veratrine | 1968 |
Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.
Topics: Adenine; Adenosine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cocaine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Guinea Pigs; Kinetics; Male; Phosphoric Diester Hydrolases; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship; Theophylline | 1974 |
Metabolism of arabinose in the ventral nerve cord of the lobster Homarus vulgaris (M.Edw.).
Topics: Ammonium Chloride; Animals; Arabinose; Aspartic Acid; Carbon Isotopes; Central Nervous System; Citric Acid Cycle; Cocaine; Crustacea; Depression, Chemical; Ethionine; Glucuronates; Glutamates; Glycolysis; Stimulation, Chemical; Sulfoxides; Taurine; Veratrine | 1969 |
Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens.
Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Calcium; Cocaine; Dose-Response Relationship, Drug; Glutamic Acid; Male; Microdialysis; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 1995 |
Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization.
Topics: Animals; Aspartic Acid; Behavior, Animal; Cocaine; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1997 |
Gender effects on persistent cerebral metabolite changes in the frontal lobes of abstinent cocaine users.
Topics: Adult; Analysis of Variance; Aspartic Acid; Central Nervous System Diseases; Choline; Cocaine-Related Disorders; Crack Cocaine; Creatine; Female; Frontal Lobe; Glutamates; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Sex Factors | 1999 |
Neurochemical adaptation to cocaine abuse: reduction of N-acetyl aspartate in thalamus of human cocaine abusers.
Topics: Adult; Aspartic Acid; Basal Ganglia; Biomarkers; Brain Chemistry; Case-Control Studies; Choline; Chronic Disease; Cocaine; Cocaine-Related Disorders; Creatine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Spectroscopy; Male; Thalamus | 1999 |
Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.
Topics: Adrenergic Uptake Inhibitors; Alkaloids; Amino Acid Substitution; Animals; Aspartic Acid; Biological Transport; Calcium-Binding Proteins; Calnexin; Carrier Proteins; Cocaine; COS Cells; HeLa Cells; Humans; Imipramine; Indole Alkaloids; Intracellular Membranes; Iodine Radioisotopes; Ion Channel Gating; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Molecular Sequence Data; N,N-Dimethyltryptamine; Nerve Tissue Proteins; Oocytes; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sodium Chloride; Transfection; Tritium; Xenopus | 1999 |
Brain proton magnetic resonance spectroscopy and imaging in children exposed to cocaine in utero.
Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Cocaine; Creatinine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Pregnancy; Prenatal Exposure Delayed Effects | 2001 |
The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Carrier Proteins; Cell Line; Cocaine; Conserved Sequence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kinetics; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Radioligand Assay; Recombinant Proteins; Transfection; Tritium; Tryptophan | 2001 |
[ACTION OF VERATRINE, COCAINE AND ELECTRIC STIMULATION ON THE SYNTHESIS AND POOLING OF AMINO ACIDS IN THE VENTRAL NERVE CORD OF THE LOBSTER].
Topics: Alanine; Alkaloids; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Cocaine; Crustacea; Electric Stimulation; Electrophysiology; Glucose; Glutamates; Glycine; Homeostasis; Lysine; Nerve Tissue Proteins; Nervous System; Pharmacology; Proteins; Pyruvates; Research; Veratrine | 1964 |
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.
Topics: Alanine; Aspartic Acid; Biological Transport; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cocaine; Cystine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutation; Nerve Tissue Proteins; Phenotype; Piperazines; Protein Binding; Protein Conformation; Protein Transport; Sodium; Time Factors; Zinc | 2004 |
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Biological Transport; Cell Line; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nerve Tissue Proteins; Norepinephrine; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism; Synaptosomes; Tritium | 2004 |
Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Benztropine; Binding, Competitive; CHO Cells; Cocaine; Cricetinae; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Immunohistochemistry; Kinetics; Ligands; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Transfection | 2005 |
Characterization of the cocaine binding site on the sigma-1 receptor.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Western; Chlorocebus aethiops; Cocaine; COS Cells; Guinea Pigs; Microsomes, Liver; Molecular Sequence Data; Receptors, sigma; Sequence Alignment; Sigma-1 Receptor | 2007 |
Occipital cortical proton MRS at 4 Tesla in human moderate MDMA polydrug users.
Topics: Adolescent; Adult; Amphetamines; Analgesics, Opioid; Aspartic Acid; Cannabis; Cocaine; Female; Hallucinogens; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; N-Methyl-3,4-methylenedioxyamphetamine; Occipital Lobe; Protons; Radiography; Substance-Related Disorders | 2007 |
Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study.
Topics: Animals; Aspartic Acid; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Extracellular Fluid; Female; Glutamic Acid; Injections, Intravenous; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred Lew; Self Administration; Time Factors | 2008 |
Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Autoradiography; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Multivariate Analysis; Protein Binding; Random Allocation; Rats; Rats, Inbred Lew; Reinforcement, Psychology; Self Administration; Time Factors; Tritium | 2008 |
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan | 2008 |
Phosphorylation of DeltaFosB mediates its stability in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain; Cocaine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Phosphorylation; Proto-Oncogene Proteins c-fos; Serine; Time Factors | 2009 |
Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Dopamine Agonists; Dopamine Uptake Inhibitors; Extracellular Space; Glutamic Acid; Male; Nucleus Accumbens; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Self Administration; Synapses; Up-Regulation | 2013 |
Single exposure to cocaine impairs aspartate uptake in the pre-frontal cortex via dopamine D1-receptor dependent mechanisms.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cocaine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Space; Gene Expression; Glutamic Acid; Mice; Phosphorylation; Prefrontal Cortex; Receptors, Dopamine D1; Serine; Signal Transduction; Time Factors | 2016 |
Cholinergic Interneurons Underlie Spontaneous Dopamine Release in Nucleus Accumbens.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Analysis of Variance; Animals; Apamin; Aspartic Acid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enkephalin, Methionine; Female; In Vitro Techniques; Interneurons; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Patch-Clamp Techniques; Potassium Channel Blockers | 2017 |
Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats.
Topics: Amino Acids; Anesthetics, Local; Animals; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Drug-Seeking Behavior; Excitatory Amino Acid Agents; Glutamic Acid; Male; Microdialysis; Microinjections; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2018 |
Mediation effect of AhR expression between polycyclic aromatic hydrocarbons exposure and oxidative DNA damage among Chinese occupational workers.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Asian People; Aspartic Acid; Carcinogens; China; Chromatography, High Pressure Liquid; Coke; Deoxyguanosine; DNA Damage; Environmental Pollutants; Fluorenes; Humans; Male; Naphthalenesulfonates; Naphthols; Occupational Exposure; Oxidative Stress; Polycyclic Aromatic Hydrocarbons; Pyrenes; Receptors, Aryl Hydrocarbon | 2018 |
Evaluation of Cocaine Effect on Endogenous Metabolites of HepG2 Cells Using Targeted Metabolomics.
Topics: Alanine; Aspartic Acid; Biomarkers; Chromatography, Liquid; Cocaine; Glutamic Acid; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Metabolic Networks and Pathways; Metabolome; Metabolomics; Multivariate Analysis; Tandem Mass Spectrometry; Taurine | 2021 |
Amino acid composition of two masticatory nuts (Cola acuminata and Garcinia kola) and a snack nut (Anacardium occidentale).
Topics: Amino Acids; Amino Acids, Acidic; Amino Acids, Essential; Anacardium; Arginine; Aspartic Acid; Cola; Cystine; Garcinia kola; Glutamic Acid; Isoelectric Point; Nuts; Threonine; Valine | 2007 |