cocaine and antipyrine

cocaine has been researched along with antipyrine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's1 (10.00)18.2507
2000's7 (70.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Jolivette, LJ; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Kelly, PA; McBean, DE; Sharkey, J1
Cheong, DK; Gangarosa, LP1
Griffeth, LK; Kloss, MW; Rauckman, EJ; Rosen, GM1
Malek, A; Obrist, C; von Mandach, U; Wenzinger, S1

Other Studies

10 other study(ies) available for cocaine and antipyrine

ArticleYear
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Acute cocaine administration: effects on local cerebral blood flow and metabolic demand in the rat.
    Brain research, 1991, May-10, Volume: 548, Issue:1-2

    Topics: Animals; Antipyrine; Blood Glucose; Blood Pressure; Brain; Cerebrovascular Circulation; Cocaine; Deoxyglucose; Drug Administration Schedule; Motor Activity; Organ Specificity; Rats; Reference Values; Regional Blood Flow

1991
Local anesthetics: inhibition of subcutaneous absorption in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:4

    Topics: Absorption; Animals; Antipyrine; Cocaine; Depression, Chemical; Injections, Subcutaneous; Lidocaine; Phosphates; Phosphorus Isotopes; Prilocaine; Procaine; Rats; Tetracaine

1970
Effect of acute cocaine administration on the metabolism of antipyrine in vivo.
    Biochemical pharmacology, 1983, Dec-15, Volume: 32, Issue:24

    Topics: Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Liver; Male; Mice; Mice, Inbred DBA

1983
The impact of cocaine and heroin on the placental transfer of methadone.
    Reproductive biology and endocrinology : RB&E, 2009, Jun-11, Volume: 7

    Topics: Antipyrine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon Radioisotopes; Cocaine; Drug Interactions; Female; Heroin; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Methadone; Narcotics; Oxidative Stress; Perfusion; Placenta; Pregnancy; Vasoconstrictor Agents

2009