cocaine has been researched along with anhydroecgonine methyl ester in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (29.17) | 18.2507 |
| 2000's | 19 (39.58) | 29.6817 |
| 2010's | 14 (29.17) | 24.3611 |
| 2020's | 1 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| de Zeeuw, RA; Ensing, JG; Racamy, C | 1 |
| Chen, LC; Graefe, JF; Willetts, J; Wood, RW | 1 |
| Chen, LC; Graefe, JF; Shojaie, J; Willetts, J; Wood, RW | 1 |
| el-Fawal, HA; Wood, RW | 1 |
| Cone, EJ; Darwin, WD; Hillsgrove, M | 1 |
| Fang, CP; Graefe, JF; Shojaie, J; Wood, RW | 1 |
| Cirimele, V; Kintz, P; Mangin, P; Sengler, C | 2 |
| Chen, LC; Fang, CP; Graefe, JF; Shojaie, J; Willetts, J; Wood, RW | 1 |
| Huang, L; Ishiguro, Y; Morgan, JP; Woolf, JH | 2 |
| Morgan, JP; Xiao, YF | 1 |
| McWhorter, LK; Paul, BD; Smith, ML | 1 |
| Fandiño, AS; Kauert, G; Toennes, SW | 1 |
| Bourland, JA; Hatab, MM; Hayes, EF; Kelly, RC; Sweeney, SA | 1 |
| Kwong, TC; Plessinger, MA; Scheidweiler, KB; Shojaie, J; Wood, RW | 2 |
| Cai, J; Ke, Q; Morgan, JP; Xiao, YF; Yang, Y | 1 |
| Hodge, GD; Paul, BD; Shimomura, ET | 1 |
| Andrews, AR; de Jager, LS | 1 |
| Cai, J; Ke, Q; Liao, H; Morgan, JP; Xiao, YF; Yang, Y | 1 |
| Fandiño, AS; Karas, M; Kauert, G; Toennes, SW | 1 |
| Fandiño, AS; Kauert, GF; Toennes, SW | 1 |
| Fortner, N; Johnson, BD; Liberty, HJ; Randolph, D | 1 |
| Fandiño, AS; Hesse, FJ; Kauert, GF; Toennes, SW | 1 |
| Bosy, T; Huestis, MA; Jacobs, AJ; Lalani, S; Paul, BD | 1 |
| Bouchonnet, S; Cognard, E; Rudaz, S; Staub, C | 1 |
| Callery, PS; Kraner, JC; Myers, AL; Williams, HE | 1 |
| Kintz, P; Ragoucy-Sengler, C | 1 |
| Hoelzle, C; Sachs, H; Scheufler, F; Thieme, D; Uhl, M | 1 |
| Barnes, AJ; Brunet, BR; Huestis, MA; Mura, P; Scheidweiler, KB | 1 |
| Chasin, AA; da Costa, JL; Tavares, MF; Tonin, FG; Zanolli, LA | 1 |
| Bjergum, MW; Crow, FW; Langman, LJ; Williamson, CL | 1 |
| Esposito, EX; Hopfinger, AJ; Shen, MY; Su, BH; Tseng, YJ | 1 |
| García-Repetto, R; Giménez, MP; Martinez, MC; Soria, ML | 1 |
| Abdalla, FM; Afeche, SC; Camarini, R; Carrettiero, DC; Dati, LM; de Carvalho, ND; Fukuda, S; Garcia, RC; Levada-Pires, AC; Marcourakis, T; Moura, S; Negrini-Neto, O; Sandoval, MR; Torres, LH; Yonamine, M | 1 |
| Drummer, OH; Pilgrim, JL; Woodford, N | 1 |
| Alvarez, JC; Bourgogne, E; Chéron, G; Miramont, S | 1 |
| Dulaurent, S; Gaulier, JM; Imbert, L; Lachâtre, G; Mercerolle, M; Morichon, J | 1 |
| Abdalla, FM; Afeche, SC; Camarini, R; Conn, PJ; da Costa, JL; da Silva, MA; Dati, LM; Garcia, RC; Gorjão, R; Marcourakis, T; Niswender, CM; Sandoval, MR; Torres, LH; Udo, MS; Yonamine, M | 1 |
| Araújo, AM; de Melo Rodrigues, LC; Gomes, EF; Lebarch, EC; Lipaus, IFS; Martins, CW; Mendonça, JB; Nakamura-Palacios, EM; Pelição, FS | 1 |
| Atkinson, S; Bailey, MJ; Costa, C; de Puit, M; Ismail, M; Palitsin, V; Webb, R | 1 |
| Chen, J; Cheng, C; Oueslati, R; Wu, J | 1 |
| Andreuccetti, G; Berg, T; Gjerde, H; Leyton, V; Takitane, J; Vindenes, V | 1 |
| Aranguren, M; Gorlelo, JC; Krumbiegel, F; Nagel, A; Poliansky, N; Pragst, F; Rubio, NC; Thurmann, D; Zytowski, E | 1 |
| Cela, R; Da Silva, KM; Estévez-Danta, A; González-Mariño, I; Quintana, JB; Rodil, R; Sodré, FF | 1 |
| Gambier, N; Van Elsue, N; Warling, J; Yegles, M | 1 |
| da Silva, MAA; Dal'Jovem, LF; de Oliveira Duro, S; de Souza Prates, S; Faião-Flores, F; Garcia, RCT; Marcourakis, T; Maria-Engler, SS; Udo, MSB | 1 |
48 other study(ies) available for cocaine and anhydroecgonine methyl ester
| Article | Year |
|---|---|
A rapid gas chromatographic method for the fingerprinting of illicit cocaine samples.
Topics: Bridged Bicyclo Compounds; Chromatography, Gas; Cocaine; Cyclobutanes; Illicit Drugs; Time Factors | 1992 |
Effects of methylecgonidine on acetylcholine-induced bronchoconstriction and indicators of lung injury in guinea pigs.
Topics: Acetylcholine; Animals; Bronchoconstriction; Cocaine; Guinea Pigs; Injections, Subcutaneous; Lung Injury; Male; Respiration | 1995 |
Pulmonary effects of the cocaine pyrolysis product, methylecgonidine, in guinea pigs.
Topics: Animals; Bronchoconstriction; Cocaine; Guinea Pigs; Hot Temperature; Male | 1995 |
Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.
Topics: Acetylcholine; Animals; Bronchodilator Agents; Carbachol; Chickens; Cocaine; Guinea Pigs; Histamine; Hot Temperature; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1995 |
Simultaneous measurement of cocaine, cocaethylene, their metabolites, and "crack" pyrolysis products by gas chromatography-mass spectrometry.
Topics: Administration, Intranasal; Body Fluids; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Injections, Intravenous; Kinetics; Male; Saliva; Sensitivity and Specificity; Smoking; Substance-Related Disorders | 1994 |
Methylecgonidine coats the crack particle.
Topics: Administration, Inhalation; Aerosols; Cocaine; Crack Cocaine; Hot Temperature; Particle Size | 1996 |
Testing human hair and urine for anhydroecgonine methyl ester, a pyrolysis product of cocaine.
Topics: Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Indicators and Reagents; Trimethylsilyl Compounds | 1995 |
Generation of stable test atmospheres of cocaine base and its pyrolyzate, methylecgonidine, and demonstration of their biological activity.
Topics: Administration, Inhalation; Aerosols; Animals; Atmosphere Exposure Chambers; Cocaine; Crack Cocaine; Hemodynamics; Male; Narcotics; Particle Size; Saimiri; Syringes | 1996 |
Evidence of crack use by anhydroecgonine methylester identification.
Topics: Cocaine; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Narcotics; Substance Abuse Detection; Sweat | 1997 |
Effect of cocaine and methylecgonidine on intracellular Ca2+ and myocardial contraction in cardiac myocytes.
Topics: Actin Cytoskeleton; Animals; Calcium; Cell Separation; Cocaine; Ferrets; Intracellular Membranes; Myocardial Contraction; Myocardium; Narcotics; Receptors, Muscarinic | 1997 |
Negative inotropic effect of methylecgonidine, a major product of cocaine base pyrolysis, on ferret and human myocardium.
Topics: Adjuvants, Anesthesia; Anesthetics, Local; Animals; Atropine; Cocaine; Cyclic AMP; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ferrets; Humans; Lidocaine; Male; Myocardial Contraction; Nitric Oxide Synthase; Papillary Muscles | 1997 |
Cocaine blockade of the acetylcholine-activated muscarinic K+ channel in ferret cardiac myocytes.
Topics: Acetylcholine; Action Potentials; Animals; Cocaine; Ferrets; Heart; Male; Potassium Channel Blockers; Receptors, Muscarinic | 1998 |
Electron ionization mass fragmentometric detection of urinary ecgonidine, a hydrolytic product of methylecgonidine, as an indicator of smoking cocaine.
Topics: Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Substance Abuse Detection | 1999 |
Gas chromatographic-mass spectrometric detection of anhydroecgonine methyl ester (methylecgonidine) in human serum as evidence of recent smoking of crack.
Topics: Acetamides; Artifacts; Cocaine; Crack Cocaine; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Organosilicon Compounds; Reference Values; Sensitivity and Specificity; Smoking | 1999 |
Quantitation of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry.
Topics: Biotransformation; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection | 2000 |
Stability of methylecgonidine and ecgonidine in sheep plasma in vitro.
Topics: Animals; Biomarkers; Cocaine; Drug Stability; Gas Chromatography-Mass Spectrometry; Sheep; Substance Abuse Detection | 2000 |
Evidence for cocaine and methylecgonidine stimulation of M(2) muscarinic receptors in cultured human embryonic lung cells.
Topics: Blotting, Western; Carbachol; Cells, Cultured; Cocaine; Cyclic AMP; Cyclic GMP; Dopamine Uptake Inhibitors; Enzyme Induction; Humans; Lung; Muscarinic Agonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Precipitin Tests; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Examination of postmortem fluids and tissues for the presence of methylecgonidine, ecgonidine, cocaine, and benzoylecgonine using solid-phase extraction and gas chromatography-mass spectrometry.
Topics: Body Fluids; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Postmortem Changes | 2001 |
Preliminary studies of a fast screening method for cocaine and cocaine metabolites in urine using hollow fibre membrane solvent microextraction (HFMSME).
Topics: Adult; Chromatography, Gas; Cocaine; Half-Life; Humans; Microchemistry; Substance Abuse Detection | 2001 |
Enhancement of nitric oxide production by methylecgonidine in cultured neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Carbachol; Cells, Cultured; Cholinergic Agonists; Cocaine; Cyclic AMP; Cyclic GMP; Enzyme Induction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Receptors, Muscarinic; Signal Transduction; Transfection | 2002 |
Identification of anhydroecgonine methyl ester N-oxide, a new metabolite of anhydroecgonine methyl ester, using electrospray mass spectrometry.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cocaine; Crack Cocaine; Heroin; Humans; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Rats; Smoking; Spectrometry, Mass, Electrospray Ionization | 2002 |
Studies on hydrolytic and oxidative metabolic pathways of anhydroecgonine methyl ester (methylecgonidine) using microsomal preparations from rat organs.
Topics: Animals; Brain; Catalysis; Cocaine; Gas Chromatography-Mass Spectrometry; Hydrolysis; Isocitrate Dehydrogenase; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution | 2002 |
Detecting crack and other cocaine use with fastpatches.
Topics: Administration, Cutaneous; Adult; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Substance Abuse Detection; Sweat; Time Factors | 2003 |
Artifact production in the assay of anhydroecgonine methyl ester in serum using gas chromatography-mass spectrometry.
Topics: Artifacts; Calibration; Cocaine; Gas Chromatography-Mass Spectrometry; Sensitivity and Specificity | 2003 |
Pharmacokinetics and pharmacodynamics of methylecgonidine, a crack cocaine pyrolyzate.
Topics: Animals; Atropine Derivatives; Blood Pressure; Cocaine; Crack Cocaine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Heart Rate; Hemodynamics; Indicators and Reagents; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Sheep | 2003 |
Concentration profiles of cocaine, pyrolytic methyl ecgonidine and thirteen metabolites in human blood and urine: determination by gas chromatography-mass spectrometry.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans | 2005 |
Analysis of cocaine and three of its metabolites in hair by gas chromatography-mass spectrometry using ion-trap detection for CI/MS/MS.
Topics: Adolescent; Adult; Calibration; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim.
Topics: Adult; Alcoholism; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Overdose; Ethanol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry | 2005 |
Detection of smoked cocaine marker (anhydroecgonine methylester) in nails.
Topics: Adult; Biomarkers; Cocaine; Crack Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Nails; Narcotics; Smoking; Substance Abuse Detection | 2005 |
Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination.
Topics: Cocaine; Discriminant Analysis; Dopamine Uptake Inhibitors; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection | 2008 |
Development and validation of a solid-phase extraction gas chromatography-mass spectrometry method for the simultaneous quantification of methadone, heroin, cocaine and metabolites in sweat.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine Derivatives; Solid Phase Extraction; Sweat | 2008 |
Simple method for determination of cocaine and main metabolites in urine by CE coupled to MS.
Topics: Cocaine; Electrophoresis, Capillary; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Sensitive method for detection of cocaine and associated analytes by liquid chromatography-tandem mass spectrometry in urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2009 |
In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage.
Topics: Carbolines; Cardiotoxins; Chemistry, Pharmaceutical; Cocaine; Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Molecular Structure; Nicotine; Quantitative Structure-Activity Relationship; Software | 2010 |
A fatally mistaken fruit juice drink: an unordinary way of cocaine intoxication.
Topics: Adult; Beverages; Citrus sinensis; Cocaine; Commerce; Crime; Forensic Pathology; Forensic Toxicology; Humans; Internet; Liver; Male; Myocardium; Narcotics; Vitreous Body | 2010 |
Neurotoxicity of anhydroecgonine methyl ester, a crack cocaine pyrolysis product.
Topics: Animals; Cells, Cultured; Cocaine; Female; Hippocampus; Immunohistochemistry; Pregnancy; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Wistar; Tritium | 2012 |
Cocaine in sudden and unexpected death: a review of 49 post-mortem cases.
Topics: Adolescent; Adult; Aged; Amphetamines; Analgesics, Opioid; Australia; Benzodiazepines; Cause of Death; Central Nervous System Depressants; Cocaine; Death, Sudden; Ethanol; Fatty Liver; Female; Forensic Pathology; Forensic Toxicology; Heart Diseases; Hepatitis C; Humans; Male; Middle Aged; Narcotics; Young Adult | 2013 |
[Passive cocaine inhalation by a 25-month-old child].
Topics: Bacterial Infections; Child, Preschool; Cocaine; Developmental Disabilities; Diagnosis, Differential; Female; Hair; Humans; Psychomotor Disorders; Seizures, Febrile; Time Factors | 2013 |
Development and validation of a single LC-MS/MS assay following SPE for simultaneous hair analysis of amphetamines, opiates, cocaine and metabolites.
Topics: Amphetamines; Analgesics, Opioid; Chromatography, Liquid; Cocaine; Forensic Toxicology; Hair; Humans; Limit of Detection; Male; Narcotics; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2014 |
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product.
Topics: Animals; Apoptosis; CHO Cells; Cocaine; Cricetinae; Cricetulus; DNA Fragmentation; Female; Hippocampus; Neurotoxicity Syndromes; Neurotoxins; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Time Factors | 2015 |
Anhydroecgonine Methyl Ester (AEME), a Product of Cocaine Pyrolysis, Impairs Spatial Working Memory and Induces Striatal Oxidative Stress in Rats.
Topics: Animals; Cocaine; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Oxidative Stress; Prefrontal Cortex; Rats, Wistar; Spatial Memory | 2018 |
Rapid, Secure Drug Testing Using Fingerprint Development and Paper Spray Mass Spectrometry.
Topics: Cocaine; Dermatoglyphics; Humans; Limit of Detection; Mass Spectrometry; Paper; Saliva; Substance Abuse Detection; Sweat | 2017 |
Highly sensitive and specific on-site detection of serum cocaine by a low cost aptasensor.
Topics: Aptamers, Nucleotide; Biosensing Techniques; Buffers; Cocaine; Electrochemical Techniques; Electrodes; Endopeptidase K; Gold; Humans; Immobilized Nucleic Acids; Kinetics; Limit of Detection; Time Factors | 2018 |
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cocaine; Crack Cocaine; Humans; Illicit Drugs; Liquid-Liquid Extraction; Mass Spectrometry; Reproducibility of Results; Substance Abuse Detection | 2018 |
Discrimination between chewing of coca leaves or drinking of coca tea and smoking of "paco" (coca paste) by hair analysis. A preliminary study of possibilities and limitations.
Topics: Acetone; Adolescent; Adult; Biomarkers; Coca; Cocaine; Cocaine-Related Disorders; Female; Hair; Humans; Male; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Smoking; Substance Abuse Detection; Tea; Young Adult | 2019 |
Profiling cocaine residues and pyrolytic products in wastewater by mixed-mode liquid chromatography-tandem mass spectrometry.
Topics: Brazil; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Cocaine; Drug Residues; Illicit Drugs; Levamisole; Pyrolysis; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2019 |
AEME production in cocaine positive hair after thermal hair treatment.
Topics: Biomarkers; Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Hair Preparations; Humans; In Vitro Techniques; Narcotics; Substance Abuse Detection | 2019 |
Anhydroecgonine methyl ester, a cocaine pyrolysis product, contributes to cocaine-induced rat primary hippocampal neuronal death in a synergistic and time-dependent manner.
Topics: Animals; Cocaine; Gas Chromatography-Mass Spectrometry; Hippocampus; Neurons; Neurotoxicity Syndromes; Pyrolysis; Rats | 2021 |