cocaine has been researched along with alpha-aminopyridine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 17 (54.84) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Chaudhry, I; Duncalf, D; Foldes, FF; Goldiner, PL; Harsing, LG; Lalezari, I; Nagashima, H; Sugimori, T; Vizi, ES | 1 |
| Koob, GF; Pich, EM; Richter, RM; Weiss, F | 1 |
| Koob, GF; Parsons, LH; Weiss, F | 1 |
| Heron-Maxwell, CL; O'Neill, MF; Shaw, G | 1 |
| Fletcher, PJ; Grottick, AJ; Higgins, GA | 2 |
| De Deurwaerdère, P; Navailles, S; Porras, G; Spampinato, U | 1 |
| Chintoh, AF; Fletcher, PJ; Higgins, GA; Sinyard, J | 1 |
| Andrews, CM; Kung, HF; Lucki, I | 1 |
| Cunningham, KA; Moison, D; Navailles, S; Spampinato, U | 1 |
| Acosta, JI; Neisewander, JL | 1 |
| Cathala, A; Cunningham, KA; Leggio, GM; Moison, D; Piazza, PV; Spampinato, U | 1 |
| Lominac, KD; McCreary, AC; McIver, G; Szumlinski, KK; Valdivia, PN; Zayara, AE | 1 |
| Baker, DA; Blacktop, JM; Ferda, N; Graf, EN; Lee, G; Mantsch, JR; Seubert, C | 1 |
| Giardino, WJ; Mark, GP; Ryabinin, AE; Stenzel-Poore, MP | 1 |
| Akil, H; Capriles, N; Watson, S | 1 |
| Butler, P; Caine, SB; Collins, GT; Gupta, P; Oberhofer, G; Ratcliffe, S; Wayman, C | 1 |
| Cooper, DA; Howell, LL; Kimmel, HL; Manvich, DF | 1 |
| Fletcher, PJ; Higgins, GA; Soko, AD | 1 |
| Abrous, DN; Cathala, A; Devroye, C; Maitre, M; Piazza, PV; Revest, JM; Spampinato, U | 2 |
| Albrechet-Souza, L; Boyson, CO; DeBold, JF; Holly, EN; Miczek, KA; Shimamoto, A; Weiner, LA | 1 |
| Der-Ghazarian, T; Neisewander, JL; Pentkowski, NS; Pockros-Burgess, LA | 1 |
| Ebben, AL; Jacobsen, AJ; Mantsch, JR; Robble, MA; Twining, RC; Wheeler, DS; Wheeler, RA | 1 |
| Platt, DM; Rüedi-Bettschen, D; Spealman, RD | 1 |
| Burke, AR; DeBold, JF; Miczek, KA | 1 |
| Mooney, J; Rawls, SM | 1 |
| Barrett, AC; Butler, P; Caine, SB; Negus, SS; Thomsen, M | 1 |
| DeBold, JF; Leonard, MZ; Miczek, KA | 1 |
| Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA | 1 |
| da Silva, AM; da Silva, MCM; de Barros Fernandes, H; de Miranda, AS; de Oliveira, ACP; Gomes, GF; Moreira, FA; Teixeira, AL | 1 |
31 other study(ies) available for cocaine and alpha-aminopyridine
| Article | Year |
|---|---|
Effect of mono- and diaminopyridines on release of [3H]norepinephrine from isolated guinea-pig atrium.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine | 1987 |
Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis.
Topics: Aminopyridines; Amygdala; Animals; Cocaine; Corticotropin-Releasing Hormone; Male; Microdialysis; Rats; Rats, Wistar | 1995 |
Serotonin1B receptor stimulation enhances cocaine reinforcement.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB.
Topics: Aminopyridines; Amphetamine; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Female; Fluorobenzenes; Indoles; Mice; Motor Activity; Piperidines; Ritanserin; Serotonin Antagonists | 1999 |
Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior.
Topics: Aminopyridines; Animals; Catalepsy; Cocaine; Conditioning, Psychological; Ethylamines; Food; Indoles; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement Schedule; Ventral Tegmental Area | 2000 |
Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding.
Topics: Aminopyridines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Male; Motor Activity; Neural Pathways; Piperidines; Quinolines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Self Administration; Serotonin; Serotonin Antagonists | 2002 |
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum.
Topics: Aminopyridines; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Electrochemistry; Ethylamines; Extracellular Space; Haloperidol; Indoles; Male; Microdialysis; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Time Factors | 2004 |
Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Ethylamines; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement Schedule; Self Administration; Serotonin 5-HT2 Receptor Antagonists; Time Factors; Ventral Tegmental Area | 2004 |
The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens.
Topics: Aminopyridines; Animals; Cocaine; Dopamine; Extracellular Space; Male; Microdialysis; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Time Factors | 2005 |
Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine.
Topics: Aminopyridines; Animals; Cocaine; Dopamine; Ethylamines; Indoles; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Ventral Tegmental Area | 2008 |
Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats.
Topics: Aminopyridines; Animals; Behavior, Addictive; Cocaine; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Indoles; Male; Motor Activity; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Self Administration | 2007 |
Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens.
Topics: Aminopyridines; Analysis of Variance; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Ethylamines; Indoles; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2009 |
Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Fluorobenzenes; Glutamic Acid; Indoles; Male; Microdialysis; Neuronal Plasticity; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Augmented cocaine seeking in response to stress or CRF delivered into the ventral tegmental area following long-access self-administration is mediated by CRF receptor type 1 but not CRF receptor type 2.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Extinction, Psychological; Flavonoids; Food Preferences; Glucosides; Male; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2011 |
Dissociation of corticotropin-releasing factor receptor subtype involvement in sensitivity to locomotor effects of methamphetamine and cocaine.
Topics: Aminopyridines; Animals; Cocaine; Female; Gene Deletion; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, Corticotropin-Releasing Hormone | 2012 |
Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats.
Topics: Aminopyridines; Animals; Cocaine; Conditioning, Psychological; Individuality; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Lack of abuse potential in a highly selective dopamine D3 agonist, PF-592,379, in drug self-administration and drug discrimination in rats.
Topics: Aminopyridines; Animals; Cocaine; Discrimination Learning; Dopamine Agonists; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Self Administration; Substance-Related Disorders; Tetrahydronaphthalenes | 2012 |
The serotonin 2C receptor antagonist SB 242084 exhibits abuse-related effects typical of stimulants in squirrel monkeys.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Drug Synergism; Indoles; Male; Receptor, Serotonin, 5-HT2C; Saimiri; Self Administration; Serotonin 5-HT2 Receptor Antagonists; Substance-Related Disorders | 2012 |
Impulsive action in the 5-choice serial reaction time test in 5-HT₂c receptor null mutant mice.
Topics: Aminopyridines; Amphetamine; Animals; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Ethylamines; Food Deprivation; Impulsive Behavior; Indoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Reaction Time; Receptor, Serotonin, 5-HT2C; Reinforcement Schedule; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2013 |
Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine.
Topics: Aminopyridines; Animals; Cocaine; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Ethylamines; Indoles; Locomotion; Male; Motor Activity; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Quinpirole; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission | 2015 |
Social stress and CRF-dopamine interactions in the VTA: role in long-term escalation of cocaine self-administration.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Microinjections; Motor Activity; Peptide Fragments; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Self Administration; Social Behavior; Social Environment; Stress, Psychological; Substance Abuse, Intravenous; Ventral Tegmental Area | 2014 |
Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behavior.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Indoles; Male; Maze Learning; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2014 |
Aversive stimuli drive drug seeking in a state of low dopamine tone.
Topics: Aminopyridines; Animals; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine; Drug-Seeking Behavior; Extinction, Psychological; Male; Nucleus Accumbens; Quinine; Rats; Rats, Sprague-Dawley; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2015 |
Serotonin2C receptor stimulation inhibits cocaine-induced Fos expression and DARPP-32 phosphorylation in the rat striatum independently of dopamine outflow.
Topics: Aminopyridines; Analysis of Variance; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Ethylamines; Indoles; Male; Microdialysis; Oncogene Proteins v-fos; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Time Factors | 2015 |
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys by direct and indirect activation of 5-HT2C receptors.
Topics: Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Ethylamines; Fluoxetine; Indoles; Saimiri; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2015 |
CRF type 1 receptor antagonism in ventral tegmental area of adolescent rats during social defeat: prevention of escalated cocaine self-administration in adulthood and behavioral adaptations during adolescence.
Topics: Adaptation, Psychological; Aminopyridines; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Disease Models, Animal; Locomotion; Male; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Social Behavior; Stress, Psychological; Ventral Tegmental Area | 2016 |
KCNQ2/3 channel agonist flupirtine reduces cocaine place preference in rats.
Topics: Aminopyridines; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; KCNQ3 Potassium Channel; Locomotion; Male; Motor Activity; Rats; Receptors, Dopamine; Reward | 2017 |
Effects of Acute and Chronic Treatments with Dopamine D
Topics: Aminopyridines; Animals; Benzamides; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Tolerance; Food; Indoles; Ligands; Male; Morpholines; Piperidines; Pyridines; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology | 2017 |
Escalated cocaine "binges" in rats: enduring effects of social defeat stress or intra-VTA CRF.
Topics: Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Infusions, Intraventricular; Male; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2017 |
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin | 2020 |
Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine.
Topics: Aminopyridines; Animals; Behavior, Animal; Brain; Chemokine CX3CL1; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Hippocampus; Inhibition, Psychological; Male; Mice; Microglia; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2021 |