cocaine has been researched along with allopurinol in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Kolassa, N; Pfleger, K; Volkmer, I | 1 |
| Aoki, K; Ohmori, M; Ota, H; Takimoto, M; Yoshida, T | 1 |
| Benes, I; Binková, B; Fried, M; Gajdos, O; Lenícek, J; Srám, RJ; Vidová, P | 1 |
| Dautréaux, B; Henry, JP; Isabelle, M; Lallemand, F; Monteil, C; Moritz, F; Mulder, P; Richard, V; Thuillez, C; Vergeade, A | 1 |
| Kohen, R; Numa, R; Portugal-Cohen, M; Yaka, R | 1 |
| Monteil, C; Mulder, P; Thuillez, C; Vendeville, C; Ventura-Clapier, R; Vergeade, A | 1 |
| Antonilli, L; Badiani, A; Grassi, MC; Graziani, M; Saso, L; Togna, AR | 1 |
1 review(s) available for cocaine and allopurinol
| Article | Year |
|---|---|
Cardiovascular and Hepatic Toxicity of Cocaine: Potential Beneficial Effects of Modulators of Oxidative Stress.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiovascular Diseases; Catecholamines; Cattle; Cocaine; Humans; Liver; Male; Mice; Mitochondria; Myocytes, Smooth Muscle; NADPH Oxidases; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Xanthine Oxidase | 2016 |
13 other study(ies) available for cocaine and allopurinol
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances].
Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil | 1969 |
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species.
Topics: Allopurinol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocaine; Enzyme Inhibitors; Guanidines; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species | 1997 |
Genotoxicity of coke-oven and urban air particulate matter in in vitro acellular assays coupled with 32P-postlabeling and HPLC analysis of DNA adducts.
Topics: Air Pollutants; Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Coke; DNA Adducts; Mutagenicity Tests; Mutagens; Occupational Exposure; Phosphorus Radioisotopes; Polycyclic Compounds; Xanthine Oxidase | 1998 |
NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction.
Topics: Acetophenones; Allopurinol; Anesthetics, Local; Animals; Cardiomyopathies; Cocaine; Enzyme Inhibitors; Male; Myocardium; NADPH Oxidases; Rats; Rats, Wistar; Reactive Oxygen Species; Up-Regulation; Ventricular Dysfunction, Left; Xanthine Dehydrogenase | 2007 |
Cocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthase.
Topics: Animals; Cell Line, Tumor; Cocaine; Dopamine Uptake Inhibitors; Glutathione; Humans; Keratinocytes; Male; Nitric Oxide Synthase; Oxidative Stress; Peroxides; Rats; Reactive Oxygen Species; Skin; Superoxides; Xanthine Oxidase | 2010 |
Xanthine oxidase contributes to mitochondrial ROS generation in an experimental model of cocaine-induced diastolic dysfunction.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Antioxidants; Cocaine; Diastole; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Enzyme Inhibitors; Hemodynamics; Male; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Ventricular Dysfunction, Left; Ventricular Function, Left; Xanthine Oxidase | 2012 |