cocaine and alanine

cocaine has been researched along with alanine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's7 (21.88)18.2507
2000's17 (53.13)29.6817
2010's2 (6.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Carl, JL; King, LJ; Lao, L1
Gilles-Baillien, M1
Ichishita, H; Odagiri, H; Shimizu, H1
Ross, SB1
Dicke, JM; Polakoski, KL; Verges, DK2
Ganapathy, V; Jayanthi, LD; Leibach, FH; Mahesh, VB; Ramamoorthy, S1
Dancis, J; Krishna, RB; Levitz, M1
Allard, P; Marcusson, JO; Ross, SB1
Kopajtic, T; Lin, Z; Revay, RS; Uhl, GR; Wang, W1
Cai, NS; Itokawa, M; Kitayama, S; Lin, Z; Uhl, GR; Wang, JB; Wu, C1
Lin, Z; Uhl, GR; Wang, W1
Mao, L; Wang, JQ1
Czoty, PW; Ginsburg, BC; Howell, LL1
Brimijoin, S; Lockridge, O; Pang, YP; Sun, H1
CHILTON, J; STENLAKE, JB1
GILLES, R; SCHOFFENIELS, E1
Gether, U; Grånäs, C; Javitch, JA; Loland, CJ1
Berfield, JL; Chen, N; Reith, ME; Rickey, J1
Glomska, H; Keller, PC; Rudnick, G; Stephan, M1
Blakely, RD; Mazei-Robison, MS1
Greengard, P; Ho, A; Kreek, MJ; Nairn, AC; Picetti, R; Schlussman, SD; Svenningsson, P; Zhang, Y1
Dar, DE; Metzger, TG; Uhl, GR; Vandenbergh, DJ1
Hixon, MS; Janda, KD; Kaufmann, GF; McKenzie, KM; Mee, JM; Rogers, CJ1
Cao, J; Desai, RI; Gerstbrein, K; Gether, U; Grundt, P; Katz, JL; Loland, CJ; Newman, AH; Sitte, HH; Zou, MF1
Castillo, MA; Nestler, EJ; Russo, SJ; Ulery-Reynolds, PG; Vialou, V1
Cha, JH; Eriksen, J; Gether, U; Newman, AH; Rasmussen, SG; Rasmussen, TN; Vaegter, CB; Zou, MF1
Aldrich, JV; Eans, SE; Ganno, ML; McLaughlin, JP; Murray, TF; Reilley, KA; Ross, NC; Senadheera, SN1
Briand, LA; Ellis, AS; Fosnocht, AQ; Lucerne, KE1
Aggelidou, E; Deda, O; Gika, H; Kritis, A; Krokos, A; Raikos, N; Theodoridis, G; Virgiliou, C1
Fadel, HH; Farouk, A1

Other Studies

32 other study(ies) available for cocaine and alanine

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cocaine and amphetamine modification of cerebral energy metabolism in vivo.
    Psychopharmacologia, 1975, Oct-14, Volume: 44, Issue:1

    Topics: Alanine; Animals; Cerebral Cortex; Citric Acid Cycle; Cocaine; Dextroamphetamine; Electric Stimulation; Energy Metabolism; Glucose; Malates; Male; Mice; Mice, Inbred ICR; Motor Activity

1975
Inorganic ions and transfer of neutral amino acids across the isolated intestinal epithelium of the tortoise "Testudo hermanni hermanni" Gmelin.
    Archives internationales de physiologie et de biochimie, 1970, Volume: 78, Issue:1

    Topics: Alanine; Animals; Biological Transport, Active; Calcium Chloride; Carbon Isotopes; Cocaine; Edetic Acid; Epithelium; Glycine; Intestinal Mucosa; Ions; Jejunum; Potassium Chloride; Sodium Chloride; Sulfates; Tromethamine; Turtles; Veratrine

1970
Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.
    The Journal of biological chemistry, 1974, Sep-25, Volume: 249, Issue:18

    Topics: Adenine; Adenosine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cocaine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Guinea Pigs; Kinetics; Male; Phosphoric Diester Hydrolases; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship; Theophylline

1974
Comparison of high affinity binding of 3H-proadifen and 3H-(-)-cocaine to rat liver membranes.
    Pharmacology & toxicology, 1995, Volume: 76, Issue:2

    Topics: Alanine; Animals; Binding, Competitive; Cadmium; Cadmium Chloride; Chlorides; Cocaine; Liver; Male; Microsomes, Liver; Proadifen; Rats; Rats, Sprague-Dawley; Subcellular Fractions

1995
The effects of cocaine on neutral amino acid uptake by human placental basal membrane vesicles.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:2

    Topics: Adult; Alanine; Binding Sites; Cell Membrane; Cocaine; Embryonic and Fetal Development; Female; Humans; In Vitro Techniques; Leucine; Placenta; Pregnancy

1994
Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Alanine; Benzimidazoles; Biological Transport; Calmodulin; Carrier Proteins; Cell Line; Cell Membrane; Choriocarcinoma; Cocaine; Female; Gene Expression; Humans; Iodine Radioisotopes; Kinetics; Leucine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Placenta; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transcription, Genetic; Tumor Cells, Cultured; Uterine Neoplasms

1994
Cocaine inhibits alanine uptake by human placental microvillous membrane vesicles.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:3

    Topics: Adult; Alanine; Binding Sites; Biological Transport, Active; Chorionic Villi; Cocaine; Culture Techniques; Dose-Response Relationship, Drug; Drug Antagonism; Female; Humans; Least-Squares Analysis; Osmolar Concentration; Pregnancy; Sodium; Time Factors

1993
Lack of effect of cocaine on lysine and alanine uptake in human placental villi or transfer in perfused human placenta.
    Reproduction, fertility, and development, 1995, Volume: 7, Issue:6

    Topics: Alanine; Biological Transport; Chorionic Villi; Cocaine; Female; Humans; Kinetics; Lysine; Placenta; Pregnancy

1995
[3H]WIN 35,428 binding in the human brain.
    Brain research, 1996, Jan-15, Volume: 706, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Brain; Cocaine; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Humans; Male; Middle Aged; Paroxetine; Radioligand Assay; Selective Serotonin Reuptake Inhibitors

1996
Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition.
    Molecular pharmacology, 1999, Volume: 56, Issue:2

    Topics: Alanine; Amino Acid Substitution; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis; Nerve Tissue Proteins; Nortropanes; Phenylalanine; Protein Structure, Secondary; Radioligand Assay; Structure-Activity Relationship; Tritium

1999
Dopamine transporter transmembrane domain polar mutants: DeltaG and DeltaDeltaG values implicate regions important for transporter functions.
    Molecular pharmacology, 2000, Volume: 57, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Protein Conformation; Rats; Transfection; Tritium

2000
Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carrier Proteins; Cations; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Conformation; Radioligand Assay; Signal Transduction; Tritium; Tryptophan

2000
Distinct inhibition of acute cocaine-stimulated motor activity following microinjection of a group III metabotropic glutamate receptor agonist into the dorsal striatum of rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:1

    Topics: Alanine; Aminobutyrates; Amphetamine; Animals; Apomorphine; Cocaine; Corpus Striatum; Excitatory Amino Acid Agonists; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate

2000
Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Alanine; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Infusions, Intravenous; Male; Microdialysis; Quipazine; Receptors, Serotonin; Reinforcement, Psychology; Saimiri; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

2002
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
    Molecular pharmacology, 2002, Volume: 62, Issue:2

    Topics: Alanine; Amino Acid Substitution; Animals; Butyrylcholinesterase; CHO Cells; Cocaine; Cricetinae; Genetic Engineering; Hydrolases; Models, Molecular; Tryptophan; Tyrosine

2002
Dissociation constants of some compounds related to lysergic acid; Beta-dimethylaminopropionic acid, dihydroarecaidine, ecgonine and their derivatives.
    The Journal of pharmacy and pharmacology, 1955, Volume: 7, Issue:12

    Topics: Alanine; Cardiovascular Agents; Cocaine; Ergot Alkaloids; Lysergic Acid; Niacin; Nicotinic Acids

1955
[ACTION OF VERATRINE, COCAINE AND ELECTRIC STIMULATION ON THE SYNTHESIS AND POOLING OF AMINO ACIDS IN THE VENTRAL NERVE CORD OF THE LOBSTER].
    Biochimica et biophysica acta, 1964, Mar-16, Volume: 82

    Topics: Alanine; Alkaloids; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Cocaine; Crustacea; Electric Stimulation; Electrophysiology; Glucose; Glutamates; Glycine; Homeostasis; Lysine; Nerve Tissue Proteins; Nervous System; Pharmacology; Proteins; Pyruvates; Research; Veratrine

1964
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Alanine; Amino Acid Sequence; Animals; Biotinylation; Blotting, Western; Cell Membrane; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Norepinephrine; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Transfection; Tyrosine; Zinc

2004
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.
    The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7

    Topics: Alanine; Aspartic Acid; Biological Transport; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cocaine; Cystine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutation; Nerve Tissue Proteins; Phenotype; Piperazines; Protein Binding; Protein Conformation; Protein Transport; Sodium; Time Factors; Zinc

2004
Cysteine-scanning mutagenesis of the fifth external loop of serotonin transporter.
    Biochemistry, 2004, Jul-06, Volume: 43, Issue:26

    Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Carrier Proteins; Cocaine; Cysteine; Dose-Response Relationship, Drug; Epitopes; HeLa Cells; Humans; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium; Threonine

2004
Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala.
    Neuropharmacology, 2005, Volume: 49, Issue:6

    Topics: Alanine; Amphetamine; Animals; Biotinylation; Cattle; Cell Line; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Gene Expression; Gene Expression Regulation; Genetic Variation; Humans; Mice; Models, Biological; Mutagenesis; Neuroblastoma; Norepinephrine; Phorbol Esters; Protein Transport; Rats; Time Factors; Transfection; Valine

2005
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-08, Volume: 26, Issue:10

    Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Phosphorylation; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serine; Threonine; Time Factors

2006
Dopamine uptake and cocaine binding mechanisms: the involvement of charged amino acids from the transmembrane domains of the human dopamine transporter.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Transfection; Tritium

2006
Identification and characterization of single chain anti-cocaine catalytic antibodies.
    Journal of molecular biology, 2007, Jan-19, Volume: 365, Issue:3

    Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Catalytic; Cocaine; Complementarity Determining Regions; DNA Mutational Analysis; Esters; Hydrolysis; Kinetics; Mice; Molecular Sequence Data; Mutant Proteins; Mutation; Sequence Alignment

2007
Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.
    Molecular pharmacology, 2008, Volume: 73, Issue:3

    Topics: Alanine; Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Cocaine; COS Cells; Data Interpretation, Statistical; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Mesylates; Motor Activity; Protein Binding; Protein Conformation; Rats; Rats, Sprague-Dawley; Transfection

2008
Phosphorylation of DeltaFosB mediates its stability in vivo.
    Neuroscience, 2009, Jan-23, Volume: 158, Issue:2

    Topics: Alanine; Animals; Aspartic Acid; Brain; Cocaine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Phosphorylation; Proto-Oncogene Proteins c-fos; Serine; Time Factors

2009
Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-27, Volume: 29, Issue:21

    Topics: Alanine; Animals; Animals, Newborn; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dynamins; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Humans; Indoles; Lysine; Maleimides; Mesencephalon; Mutation; Neurons; Phorbol Esters; Protein Transport; rab5 GTP-Binding Proteins; Rats; Receptors, Transferrin; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2009
Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour.
    British journal of pharmacology, 2014, Volume: 171, Issue:13

    Topics: Alanine; Amino Acids; Analgesics, Opioid; Animals; Behavior, Animal; CHO Cells; Cocaine; Conditioning, Psychological; Cricetulus; Drug-Seeking Behavior; Male; Mice; Mice, Inbred C57BL; Narcotic Antagonists; Peptides, Cyclic; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Psychological; Time Factors

2014
Disruption of GluA2 phosphorylation potentiates stress responsivity.
    Behavioural brain research, 2017, 08-30, Volume: 333

    Topics: Alanine; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Female; Gene Expression Regulation; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phosphorylation; Protein Kinase C; Receptors, AMPA; Stress, Psychological; Swimming

2017
Evaluation of Cocaine Effect on Endogenous Metabolites of HepG2 Cells Using Targeted Metabolomics.
    Molecules (Basel, Switzerland), 2021, Jul-29, Volume: 26, Issue:15

    Topics: Alanine; Aspartic Acid; Biomarkers; Chromatography, Liquid; Cocaine; Glutamic Acid; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Metabolic Networks and Pathways; Metabolome; Metabolomics; Multivariate Analysis; Tandem Mass Spectrometry; Taurine

2021
Caramelization of maltose solution in presence of alanine.
    Amino acids, 2002, Volume: 22, Issue:2

    Topics: Alanine; Candy; Carbohydrates; Flavoring Agents; Food Coloring Agents; Maltose; Organic Chemicals; Sensitivity and Specificity; Smell; Volatilization

2002