cocaine and acetaminophen

cocaine has been researched along with acetaminophen in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.43)18.7374
1990's3 (8.57)18.2507
2000's14 (40.00)29.6817
2010's10 (28.57)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Shaw, K; Shuster, L; Thompson, ML1
Knodell, RG; Peterson, FJ1
Knodell, RG; Lindemann, NJ; Peterson, FJ; Steele, NM1
Goodman, DR; Harbison, RD; James, RC1
Henretig, FM1
Roberts, SM; Salminen, WF; Voellmy, R1
Baskin, LB; Morgan, DL1
Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT1
Bahl, S; Brissette, S; Bruneau, J; El-Guebaly, N; Fallu, JS; Fischer, B; Leri, F; Monga, N; Noël, L; Rehm, J; Tyndall, M; Wild, C1
Birchenough, SA; Borowitz, K; Lin, KY1
Ali, EM; Edwards, HG; Hargreaves, MD; Scowen, IJ1
Gostic, T; Klemenc, S; Stefane, B1
Caballero Vallés, PJ; Cantero Bengoechea, J; Díaz Brasero, A; Dorado Pombo, S; García Gil, ME; Ibero Esparza, C; Torres Pacho, N; Yubero Salgado, L1
Cadet-Taïrou, A; Evrard, I; Legleye, S1
Maguire, J; Mauck, KF; Smith, SB1
Boleda, MA; Galceran, MA; Ventura, F1
Hantson, P; Wittebole, X1
Michalow, KA; Mielczarek, P; Raoof, H; Rekas, M; Silberring, J1
Choi, YC; Mak, PY; Man, SH; Ng, KM; Tang, HW; Wong, MY1
Alonso-Lomillo, MA; Arcos-Martínez, MJ; Asturias-Arribas, L; Domínguez-Renedo, O1
Gonzalez, J; Hastedt, M; Pragst, F; Rubio, NC1
Camilleri, R1
Antunes, MM; David, BA; Diniz, AB; Gomides, LF; Menezes, GB; Moreira, Fde A; Vilela, LR1
Baker, SD; Choi, BY; Choi, NG; DiNitto, DM; Marti, CN1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W2
Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V1

Reviews

3 review(s) available for cocaine and acetaminophen

ArticleYear
Special considerations in the poisoned pediatric patient.
    Emergency medicine clinics of North America, 1994, Volume: 12, Issue:2

    Topics: Acetaminophen; Alcoholic Intoxication; Astemizole; Child; Child, Preschool; Clonidine; Cocaine; Critical Care; Dextromethorphan; Drug Overdose; Female; Humans; Hydrocarbons; Infant; Insecticides; Iron; Male; Organophosphorus Compounds; Poisoning

1994
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:9

    Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Heavy Metal Poisoning; Humans; Lamotrigine; Liver Failure; Liver, Artificial; Metals, Heavy; Mushroom Poisoning; Phenytoin; Poisoning; Sorption Detoxification; Triazines

2011
A meta-analysis of the reliability of the history in suspected poisoning.
    The Journal of emergency medicine, 2015, Volume: 48, Issue:6

    Topics: Acetaminophen; Acute Disease; Cocaine; Drug Overdose; Humans; Medical History Taking; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Poisoning

2015

Trials

1 trial(s) available for cocaine and acetaminophen

ArticleYear
Effects of repeated-dose isradipine on the abuse liability of cocaine.
    Experimental and clinical psychopharmacology, 2005, Volume: 13, Issue:4

    Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Euphoria; Female; Headache; Heart Rate; Humans; Infusions, Intravenous; Isradipine; Male; Middle Aged; Nausea; Tablets; Treatment Outcome

2005

Other Studies

31 other study(ies) available for cocaine and acetaminophen

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism.
    Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Proadifen; Sleep

1979
Ascorbic acid protects against acetaminophen- and cocaine-induced hepatic damage in mice.
    Drug-nutrient interactions, 1984, Volume: 3, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Animals; Ascorbic Acid; Cocaine; Glutathione; Liver; Male; Mice; Mice, Inbred Strains

1984
Prevention of acetaminophen and cocaine hepatotoxicity in mice by cimetidine treatment.
    Gastroenterology, 1983, Volume: 85, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Cocaine; Cytochrome P-450 Enzyme System; Guanidines; Kinetics; Liver; Male; Mice; Premedication

1983
Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Narcotics; Proadifen; Time Factors

1982
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction.
    Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2

    Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cocaine; Fever; Heat-Shock Proteins; Hyperthermia, Induced; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred ICR

1997
Drugs detected in patients suspected of acute intoxication.
    Texas medicine, 1997, Volume: 93, Issue:9

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholic Intoxication; Amphetamines; Analgesics, Non-Narcotic; Barbiturates; Cannabinoids; Chromatography, High Pressure Liquid; Cocaine; Drug Overdose; Enzyme Multiplied Immunoassay Technique; Ethanol; Female; Forecasting; Hallucinogens; Humans; Male; Middle Aged; Narcotics; Phencyclidine; Poisoning; Retrospective Studies; Salicylates; Substance-Related Disorders

1997
Using latent class analysis (LCA) to analyze patterns of drug use in a population of illegal opioid users.
    Drug and alcohol dependence, 2007, Apr-17, Volume: 88, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Opioid; Benzodiazepines; Canada; Chi-Square Distribution; Cocaine; Cohort Studies; Female; Humans; Male; Odds Ratio; Substance-Related Disorders; Urban Population

2007
Complete soft palate necrosis and velopharyngeal insufficiency resulting from intranasal inhalation of prescription narcotics and cocaine.
    The Journal of craniofacial surgery, 2007, Volume: 18, Issue:6

    Topics: Acetaminophen; Administration, Inhalation; Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Deglutition Disorders; Drug Combinations; Female; Hearing Loss, Conductive; Humans; Necrosis; Nose Deformities, Acquired; Opioid-Related Disorders; Otitis Media with Effusion; Oxycodone; Palate, Soft; Surgical Flaps; Vasoconstrictor Agents; Velopharyngeal Insufficiency

2007
Raman spectroscopic investigation of cocaine hydrochloride on human nail in a forensic context.
    Analytical and bioanalytical chemistry, 2008, Volume: 390, Issue:4

    Topics: Acetaminophen; Cocaine; Forensic Medicine; Humans; Nails; Spectrum Analysis, Raman

2008
A study of the thermal decomposition of adulterated cocaine samples under optimized aerobic pyrolytic conditions.
    Forensic science international, 2009, May-30, Volume: 187, Issue:1-3

    Topics: Acetaminophen; Administration, Inhalation; Calorimetry, Differential Scanning; Cocaine; Drug Combinations; Drug Contamination; Hot Temperature; Lidocaine; Magnetic Resonance Spectroscopy; Procaine; Smoke; Smoking; Volatilization

2009
[Epidemiologic survey of acute poisoning in the south area of the Community of Madrid: the VEIA 2004 study].
    Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:6

    Topics: Accidents, Home; Accidents, Occupational; Acetaminophen; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alcoholic Intoxication; Antidepressive Agents; Benzodiazepines; Chi-Square Distribution; Cocaine; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Incidence; Male; Middle Aged; Poisoning; Population Surveillance; Registries; Sex Factors; Spain; Suicide, Attempted

2008
Composition, purity and perceived quality of street cocaine in France.
    The International journal on drug policy, 2010, Volume: 21, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Data Collection; Diltiazem; Drug Contamination; Drug Users; Female; France; Humans; Illicit Drugs; Lidocaine; Male; Middle Aged; Smoking; Young Adult

2010
Clinical cases in acute intoxication.
    Hospital practice (1995), 2009, Volume: 37, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Central Nervous System Diseases; Cocaine; Cocaine-Related Disorders; Drug Overdose; Emergency Service, Hospital; Ethylene Glycol; Female; Humans; Male; Middle Aged; Young Adult

2009
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
    Environmental pollution (Barking, Essex : 1987), 2011, Volume: 159, Issue:6

    Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply

2011
Synthesis of metabolites of paracetamol and cocaine via photooxidation on TiO2 catalyzed by UV light.
    Journal of photochemistry and photobiology. B, Biology, 2013, Jan-05, Volume: 118

    Topics: Acetaminophen; Animals; Catalysis; Cocaine; Microsomes, Liver; Oxidation-Reduction; Photochemical Processes; Photolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Titanium; Ultraviolet Rays

2013
Direct analysis of large living organism by megavolt electrostatic ionization mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2014, Volume: 25, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Breath Tests; Cocaine; Equipment Design; Explosive Agents; Gloves, Protective; Humans; Illicit Drugs; Paper; Spectrometry, Mass, Electrospray Ionization; Static Electricity; Volatile Organic Compounds

2014
Sensitive and selective cocaine electrochemical detection using disposable sensors.
    Analytica chimica acta, 2014, Jun-27, Volume: 834

    Topics: Acetaminophen; Anesthetics, Local; Caffeine; Cocaine; Codeine; Electrochemical Techniques; Electrodes; Least-Squares Analysis; Limit of Detection; Nanotubes, Carbon; Oxidation-Reduction; Reproducibility of Results; Substance Abuse Detection

2014
Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.
    International journal of legal medicine, 2015, Volume: 129, Issue:1

    Topics: Acetaminophen; Acetone; Adolescent; Adult; Aged; Chromatography, Liquid; Coca; Cocaine; Cocaine-Related Disorders; Drug and Narcotic Control; Drug Contamination; Female; Forensic Toxicology; Hair; Humans; Levamisole; Lidocaine; Male; Mass Spectrometry; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Tea

2015
Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Acetaminophen; Alanine Transaminase; Animals; Cannabidiol; Cocaine; Inflammation; Liver; Male; Mice; Seizures

2015
Opioid poisoning cases aged 50+ in the 2015-2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Acetaminophen; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Benzodiazepines; Cocaine; Fentanyl; Humans; Middle Aged; Poisons; Practice Patterns, Physicians'; Suicide; Tramadol

2022
Occurrence of pharmaceuticals and cocaine in the urban drainage channels located on the outskirts of the São Vicente Island (São Paulo, Brazil) and related ecological risk assessment.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:38

    Topics: Acetaminophen; Brazil; Caffeine; Carbamazepine; Cocaine; Environmental Monitoring; Humans; Losartan; Pharmaceutical Preparations; Risk Assessment; Water Pollutants, Chemical

2022
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:42

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical

2022
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:59

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical

2022
Flurbiprofen: new indication. Lozenges: NSAIDs are not to be taken like sweets!
    Prescrire international, 2007, Volume: 16, Issue:87

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Candy; Chemistry, Pharmaceutical; Consumer Product Safety; Cost-Benefit Analysis; Drug Approval; Flurbiprofen; France; Humans; Nonprescription Drugs; Pharyngitis

2007