cocaine and 8-hydroxy-2-(di-n-propylamino)tetralin

cocaine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.77)	18.7374
1990's	23 (43.40)	18.2507
2000's	22 (41.51)	29.6817
2010's	6 (11.32)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP	1
Glennon, RA	1
Cunningham, KA; Goeders, NE; Paris, JM	1
Carlsson, A; Hoffmann, WE; Ljung, E; Lum, JT; Piercey, MF; Svensson, K	1
Callahan, PM; Cunningham, KA; Piercey, MF	1
Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D	1
Bobker, DH; Williams, JT	1
Piercey, M; Roberts, DC; Smith, A	1
Baumann, MH; Becketts, KM; Rothman, RB	1
Fiorella, D; Johnson, RG; Rabin, RA	1
Baumann, MH; Rothman, RB	2
Kling-Petersen, T; Ljung, E; Svensson, K	1
Peltier, R; Schenk, S	1
Chen, NH; Reith, ME	1
Battaglia, G; Cabrera, TM	1
Cheng, CH; Costall, B; Naylor, RJ; Rudd, JA	1
Ellinwood, EH; Joyner, CM; King, GR	1
Davis, JM; Javaid, JI; Pandey, SC; Sahni, SK	1
Gallagher, JP; Simms, D	1
Koob, GF; Parsons, LH; Weiss, F	2
Meltzer, HY; Willins, DL	1
Callahan, PM; Cunningham, KA; De La Garza, R	1
Battaglia, G; Cabrera-Vera, TM; Garcia, F; Pinto, W; Van de Kar, LD; Vicentic, A	1
Filip, M; Przegaliñski, E	1
Cunningham, KA; De La Garza, R	1
Carey, R; Damianopoulos, E; De Palma, G	1
Carey, RJ; Damianopoulos, E; DePalma, G	2
Carey, RJ; Damianopoulos, E; De Palma, G	1
Carey, RJ; Huston, JP; Müller, CP; Salloum, JB	1
Frys, KA; Kalivas, PW; Szumlinski, KK	1
Carey, RJ; Damianopoulos, E; Depalma, G; Huston, JP; Müller, CP	1
Bert, B; Carey, RJ; De Souza Silva, MA; Fink, H; Huston, JP; Müller, CP; Thönnessen, H	1
Barros, M; Carey, RJ; Huston, JP; Müller, CP; Thönnessen, H; Tomaz, C	1
Carey, RJ; Damianopoulos, E; DePalma, G; Huston, JP; Müller, CP; Shanahan, A	2
Czoty, PW; McCabe, C; Nader, MA	1
Battaglia, G; Carrasco, GA; Chen, Z; Muma, NA; Shankaran, M; Sripathirathan, K; Tetzlaff, J; Van De Kar, LD	1
Knyshevski, I; McCann, TE; Melloni, RH; Ricci, LA	1
Carey, RJ; Damianopoulos, E; DePalma, G; Shanahan, A	1
Francis, D; Harley, J; Hubert, GW; Kuhar, MJ; Lakatos, A; Moffett, M; Rogge, G; Vicentic, A	1
Chang-Fong, J; Dukat, M; El-Zahabi, M; Glennon, RA; Young, R	1
Carey, RJ; Damianopoulos, EN; DePalma, G; Huston, JP; Müller, CP; Shanahan, A	1
Madeira, E; Santucci, AC	1
Burns, RM; Gulley, JM; Sherrill, LK; Stanis, JJ	1
Carey, RJ; Damianopoulos, EN; Shanahan, AB	1
Cheng, FC; Feng, JJ; Lin, CH; Wei, JW; Yang, SD	1
Jakovcevski, M; Morellini, F; Schachner, M	1
Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G	1
Amicarelli, M; Blakely, RD; Glass, JD; Nackenoff, AG; Prosser, RA; Stowie, A	1
Glass, JD; Prosser, RA; Woodruff, RW; Yaw, AM	1

Other Studies

53 other study(ies) available for cocaine and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. Journal of medicinal chemistry, 1989, Volume: 32, Issue:5 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship	1989
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin	2017
Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse (New York, N.Y.), 1992, Volume: 11, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Electrophysiology; Fluoxetine; Male; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes	1992
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232. Brain research, 1992, Aug-21, Volume: 588, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Electrophysiology; Homovanillic Acid; Male; Microelectrodes; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes	1992
Effects of the putative dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 on the discriminative stimulus properties of cocaine. Psychopharmacology, 1992, Volume: 107, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes	1992
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; In Vitro Techniques; Indoles; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Renal Artery; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Sympathectomy; Tetrahydronaphthalenes; Tyramine; Vasoconstrictor Agents; Vasodilation	1991
Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Cocaine; Electric Stimulation; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Neurons; Picrotoxin; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes	1989
Effect of (-)-DS 121 and (+)-UH 232 on cocaine self-administration in rats. Psychopharmacology, 1995, Volume: 120, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Nitriles; Piperidines; Rats; Rats, Inbred Strains; Self Administration	1995
Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats. European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Corticosterone; Fenfluramine; Humans; Male; Neurosecretory Systems; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Substance Withdrawal Syndrome	1995
Effects of chronic cocaine administration on the serotonergic system in the rat brain. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin	1993
Repeated cocaine administration reduces 5-HT1A-mediated prolactin secretion in rats. Neuroscience letters, 1995, Jun-23, Volume: 193, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Injections, Intravenous; Male; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin; Sodium Chloride; Time Factors	1995
The preferential dopamine autoreceptor antagonist (+)-UH232 antagonizes the positive reinforcing effects of cocaine and d-amphetamine in the ICSS paradigm. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cocaine; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes; Haloperidol; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Stimulation	1994
Effects of serotonergic manipulations on cocaine self-administration in rats. Psychopharmacology, 1993, Volume: 110, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement Schedule; Self Administration; Serotonin; Serotonin Receptor Agonists	1993
Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin. Journal of neurochemistry, 1995, Volume: 64, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Cocaine; Dioxanes; Idazoxan; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sulpiride; Tegmentum Mesencephali	1995
Potentiation of 5-HT1A receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: evidence for gender differences. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Renin; Serotonin; Sex Factors	1994
The effect of 5-HT receptor ligands on the uptake of [3H]5-hydroxytryptamine into rat cortical synaptosomes. European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cocaine; Desipramine; Female; Fluoxetine; In Vitro Techniques; Indoles; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptosomes; Tropisetron	1993
Withdrawal from continuous or intermittent cocaine: behavioral responsivity to 5-HT1 receptor agonists. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Drug Tolerance; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome	1993
Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions. European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Hippocampus; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereotyped Behavior	1993
Modification of serotonin responses in rat dorsolateral septal nucleus neurons by acute and chronic cocaine. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Male; Neurons; Rats; Rats, Sprague-Dawley; Septal Nuclei; Serotonin	1996
Serotonin1b receptor stimulation enhances dopamine-mediated reinforcement. Psychopharmacology, 1996, Volume: 128, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Narcotics; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Receptor Agonists	1996
Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens. Brain research, 1998, Jan-19, Volume: 781, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Morphine; Narcotic Antagonists; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists	1998
The discriminative stimulus properties of cocaine: effects of microinfusion of cocaine, a 5-HT1A agonist or antagonist, into the ventral tegmental area. Psychopharmacology, 1998, Volume: 137, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Microinjections; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ventral Tegmental Area	1998
Prenatal cocaine exposure produces long-term impairments in brain serotonin function in rat offspring. Annals of the New York Academy of Sciences, 1998, Jun-21, Volume: 846 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Brain; Cocaine; Female; Gestational Age; Male; p-Chloroamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Renin; Serotonin	1998
Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans. Biological psychiatry, 1998, Oct-01, Volume: 44, Issue:7 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Cocaine; Depressive Disorder; Dopamine Uptake Inhibitors; Feeding Behavior; Fenfluramine; Male; Prolactin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome	1998
Serotonin1B receptor stimulation enhances cocaine reinforcement. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists	1998
Stimulation of serotonin (5-HT)1A receptors attenuates the locomotor, but not the discriminative, effects of amphetamine and cocaine in rats. Behavioural pharmacology, 1997, Volume: 8, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Cocaine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stimulation, Chemical	1997
The effects of the 5-hydroxytryptamine(1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin on spontaneous activity, cocaine-induced hyperactivity and behavioral sensitization: a microanalysis of locomotor activity. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Hyperkinesis; Locomotion; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Time Factors	2000
8-OH DPAT can restore the locomotor stimulant effects of cocaine blocked by haloperidol. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Haloperidol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Time Factors	2000
Cocaine and serotonin: a role for the 5-HT(1A) receptor site in the mediation of cocaine stimulant effects. Behavioural brain research, 2001, Nov-29, Volume: 126, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Brain; Cocaine; Corticosterone; Dopamine; Grooming; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Stimulation, Chemical	2001
5-HT1A agonist/antagonist modification of cocaine stimulant effects: implications for cocaine mechanisms. Behavioural brain research, 2002, Apr-15, Volume: 132, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Brain; Caffeine; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Grooming; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior	2002
8-OHDPAT effects upon cocaine unconditioned and conditioned behaviors: a role for drug stimulus effects. Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Combinations; Male; Motor Activity; Rats; Rats, Sprague-Dawley	2002
Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology, 2003, Volume: 44, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Drug Synergism; Hippocampus; Locomotion; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists	2003
Dissociable roles for the dorsal and median raphé in the facilitatory effect of 5-HT1A receptor stimulation upon cocaine-induced locomotion and sensitization. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists	2004
The 5-HT1A receptor and behavioral stimulation in the rat: effects of 8-OHDPAT on spontaneous and cocaine-induced behavior. Psychopharmacology, 2004, Volume: 177, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists	2004
Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology, 2004, Volume: 47, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists	2004
Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus, 2004, Volume: 14, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Up-Regulation	2004
Evidence that the 5-HT1A autoreceptor is an important pharmacological target for the modulation of cocaine behavioral stimulant effects. Brain research, 2005, Feb-09, Volume: 1034, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2005
Effects of the 5-HT(1A) agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on cocaine choice in cynomolgus monkeys. Behavioural pharmacology, 2005, Volume: 16, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Macaca fascicularis; Male; Receptor, Serotonin, 5-HT1A; Reinforcement, Psychology; Serotonin Receptor Agonists	2005
Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine. Psychopharmacology, 2005, Volume: 180, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Growth; Oxytocin; Paroxetine; Piperazines; Pregnancy; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Renin; Weight Gain	2005
Serotonin type-1A receptors modulate adolescent, cocaine-induced offensive aggression in hamsters. Physiology & behavior, 2005, Jun-02, Volume: 85, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Aggression; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cricetinae; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Reaction Time; Receptor, Serotonin, 5-HT1A; Serotonin Agents; Time Factors	2005
Pharmacological inhibition of DA- and 5-HT activity blocks spontaneous and cocaine-activated behavior: reversal by chronic cocaine treatment. Brain research, 2005, Jun-21, Volume: 1047, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Cocaine; Conditioning, Classical; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists	2005
Stimulus gated cocaine sensitization: interoceptive drug cue control of cocaine locomotor sensitization. Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Central Nervous System Stimulants; Cocaine; Cues; Dopamine Agonists; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reproducibility of Results	2005
Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain. Neuroscience, 2006, Jun-19, Volume: 140, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Brain; Carrier Proteins; Cocaine; Female; Gene Expression Regulation, Developmental; Iodine Radioisotopes; Male; Maternal Deprivation; Piperazines; Pregnancy; Pyridines; Radioimmunoassay; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists	2006
N-Methyl-1-(4-methoxyphenyl)-2-aminopropane (PMMA) and N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) produce non-identical discriminative stimuli in rats. Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Discrimination, Psychological; Illicit Drugs; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship	2007
Effects on spontaneous and cocaine-induced behavior of pharmacological inhibition of noradrenergic and serotonergic systems. Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Dopamine Uptake Inhibitors; Limbic System; Male; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists; Sympathetic Nervous System	2008
Anxiogenesis in adult rats treated chronically with cocaine during adolescence: effects of extended abstinence and 8-OH-DPAT treatment. Brain research bulletin, 2008, Jul-01, Volume: 76, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Anxiety Disorders; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Administration Schedule; Exploratory Behavior; Male; Maze Learning; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Substance Withdrawal Syndrome	2008
Disparate cocaine-induced locomotion as a predictor of choice behavior in rats trained in a delay-discounting task. Drug and alcohol dependence, 2008, Nov-01, Volume: 98, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Impulsive Behavior; Individuality; Male; Motivation; Motor Activity; Rats; Reaction Time; Reinforcement Schedule; Risk Factors; Serotonin Receptor Agonists	2008
Cocaine conditioning: reversal by autoreceptor dose levels of 8-OHDPAT. Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Cocaine; Conditioning, Operant; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2009
Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [(3)H]8-OH-DPAT and other serotonergic ligands. Archives of biochemistry and biophysics, 2011, Feb-01, Volume: 506, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Biogenic Amines; Cocaine; Fluoxetine; HeLa Cells; Humans; Kinetics; Ligands; Paroxetine; Radioligand Assay; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Vesicular Biogenic Amine Transport Proteins	2011
Susceptibility to the long-term anxiogenic effects of an acute stressor is mediated by the activation of the glucocorticoid receptors. Neuropharmacology, 2011, Volume: 61, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Hormone Antagonists; Hypothalamus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mifepristone; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serotonin Receptor Agonists; Stress, Psychological; Time Factors; Tyrosine 3-Monooxygenase	2011
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. Journal of neurochemistry, 2012, Volume: 120, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists	2012
Cocaine modulates mammalian circadian clock timing by decreasing serotonin transport in the SCN. Neuroscience, 2014, Sep-05, Volume: 275 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Clocks; Circadian Rhythm; Cocaine; Dopamine Uptake Inhibitors; Mice; Mice, Transgenic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Suprachiasmatic Nucleus	2014
Paternal Cocaine Disrupts Offspring Circadian Clock Function in a Sex-Dependent Manner in Mice. Neuroscience, 2018, 05-21, Volume: 379 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Circadian Clocks; Cocaine; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Fathers; Female; Male; Mice, Inbred C57BL; Motor Activity; Serotonin Receptor Agonists; Sex Characteristics	2018