Compounds > cocaine

cocaine and 4-aminopyridine

cocaine has been researched along with 4-aminopyridine in 9 studies

*4-Aminopyridine: One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes. [MeSH]

*4-Aminopyridine: One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes. [MeSH]

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chaudhry, I; Duncalf, D; Foldes, FF; Goldiner, PL; Harsing, LG; Lalezari, I; Nagashima, H; Sugimori, T; Vizi, ES1
Avor, KS; Basmadjian, GP; Chang, F; Mills, SL; Sastrodjojo, B; Seale, TW; Singh, S; Smith, BT1
Barrett, JE; Rosenzweig-Lipson, S; Thomas, S1
Artaud, F; Borrelli, E; Chéramy, A; Glowinski, J; Godeheu, G; L'hirondel, M; Saiardi, A1
de Gusmao, CM; Ortega, MR; Wallace, DM1
Williams, JT; Yorgason, JT; Zeppenfeld, DM1
Brundage, JN; Finuf, CS; Jones, SR; Mason, CP; Nelson, JJ; Ronström, PJW; Siciliano, CA; Steffensen, SC; Wadsworth, HA; Yorgason, JT1

Other Studies

9 other study(ies) available for cocaine and 4-aminopyridine

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Effect of mono- and diaminopyridines on release of [3H]norepinephrine from isolated guinea-pig atrium.
    Neuropharmacology, 1987, Volume: 26, Issue:6

    Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine

1987
Generation of polyclonal catalytic antibodies against cocaine using transition state analogs of cocaine conjugated to diphtheria toxoid.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:11

    Topics: 4-Aminopyridine; Animals; Antibodies; Antibody Specificity; Catalysis; Cocaine; Dicyclohexylcarbodiimide; Diphtheria Toxoid; Enzyme-Linked Immunosorbent Assay; Esterification; Hydrolysis; In Vitro Techniques; Mice; Mice, Inbred C57BL; Phosphorylation; Structure-Activity Relationship

1995
Attenuation of the locomotor activating effects of D-amphetamine, cocaine, and scopolamine by potassium channel modulators.
    Progress in neuro-psychopharmacology & biological psychiatry, 1997, Volume: 21, Issue:5

    Topics: 4-Aminopyridine; Animals; Apamin; Central Nervous System Stimulants; Cocaine; Cromakalim; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Muscarinic Antagonists; Potassium Channels; Quinine; Scopolamine

1997
Lack of autoreceptor-mediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: 4-Aminopyridine; Amphetamine; Animals; Apomorphine; Autoreceptors; Benzopyrans; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoresceins; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Inhibition; Oxazines; Potassium Chloride; Presynaptic Terminals; Quinpirole; Receptors, Dopamine D2; Synaptosomes; Tritium

1998
Status epilepticus associated with dalfampridine in a patient with multiple sclerosis.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Fall, Volume: 24, Issue:4

    Topics: 4-Aminopyridine; Cocaine; Humans; Male; Middle Aged; Multiple Sclerosis; Potassium Channel Blockers; Status Epilepticus

2012
Cholinergic Interneurons Underlie Spontaneous Dopamine Release in Nucleus Accumbens.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-22, Volume: 37, Issue:8

    Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Analysis of Variance; Animals; Apamin; Aspartic Acid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enkephalin, Methionine; Female; In Vitro Techniques; Interneurons; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Patch-Clamp Techniques; Potassium Channel Blockers

2017
Regional and sex differences in spontaneous striatal dopamine transmission.
    Journal of neurochemistry, 2022, Volume: 160, Issue:6

    Topics: 4-Aminopyridine; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Male; Mice; Nucleus Accumbens; Sex Characteristics

2022