Compounds > cocaine

cocaine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

cocaine has been researched along with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Steketee, JD3
Bertaglia, A; Cervo, L; Mukherjee, S; Samanin, R1
Krnjević, K; Liu, PL; McArdle, JJ; Ren, J; Ye, JH1
Cuevas, J; Henning, RJ1
Allen, AG; DePoy, LM; Gourley, SL; Noble, B1
Abbott, TB; Chung, L; Colangelo, CM; Gulcicek, EE; Lam, TT; Nairn, AC; Rich, MT; Stone, KL; Taylor, JR; Torregrossa, MM1
DePoy, LM; Gourley, SL; Swanson, AM1

Other Studies

9 other study(ies) available for cocaine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

ArticleYear
Intra-A10 injection of H7 blocks the development of sensitization to cocaine.
    Neuroreport, 1994, Dec-30, Volume: 6, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cocaine; Injections; Isoquinolines; Limbic System; Male; Motor Activity; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley

1994
Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: behavioral and in vivo microdialysis studies.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Cocaine; Dopamine; Isoquinolines; Limbic System; Male; Microdialysis; Microinjections; Motor Activity; Neurons; Nucleus Accumbens; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley

1993
Intra-ventral tegmental area administration of H7 delays, but does not prevent the development of cocaine-induced sensitization.
    Brain research bulletin, 1997, Volume: 43, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Behavior, Animal; Cocaine; Dopamine; Enzyme Inhibitors; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali; Time Factors

1997
Protein kinases A and C are involved in the mechanisms underlying consolidation of cocaine place conditioning.
    Brain research, 1997, Nov-14, Volume: 775, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Benzophenanthridines; Cocaine; Conditioning, Operant; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Injections, Intraventricular; Isoquinolines; Male; Motor Activity; Narcotics; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides

1997
Cocaine decreases the glycine-induced Cl- current of acutely dissociated rat hippocampal neurons.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Anesthetics, Local; Animals; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Cocaine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Glycine Agents; Hippocampus; Isoquinolines; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Strychnine; Sulfonamides; Tetrodotoxin

1999
Cocaine activates calcium/calmodulin kinase II and causes cardiomyocyte hypertrophy.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium Channels; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Heart Ventricles; Hypertrophy; Male; Membrane Potentials; Myocytes, Cardiac; Myosin Heavy Chains; Patch-Clamp Techniques; Peptides; Phenylephrine; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Sprague-Dawley; Sarcolemma

2006
Developmentally divergent effects of Rho-kinase inhibition on cocaine- and BDNF-induced behavioral plasticity.
    Behavioural brain research, 2013, Apr-15, Volume: 243

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Female; Male; Mice; Mice, Biozzi; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Protein Kinase Inhibitors; Reward; rho-Associated Kinases

2013
Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 07-20, Volume: 36, Issue:29

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amygdala; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Conditioning, Operant; Cues; Enzyme Inhibitors; Extinction, Psychological; HEK293 Cells; Humans; Male; Memory; Phosphorylation; Proteomics; Rats; Rats, Sprague-Dawley; Self Administration; Serine; Signal Transduction; Sulfonamides

2016
Inhibiting Rho kinase promotes goal-directed decision making and blocks habitual responding for cocaine.
    Nature communications, 2017, 11-30, Volume: 8, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cocaine; Conditioning, Operant; Decision Making; Dendritic Spines; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Goals; Mice; Neuronal Plasticity; Prefrontal Cortex; Protein Kinase Inhibitors; Reinforcement, Psychology; rho-Associated Kinases; Self Administration

2017