cocaine and 1-(3-chlorophenyl)piperazine

cocaine has been researched along with 1-(3-chlorophenyl)piperazine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's5 (35.71)18.2507
2000's5 (35.71)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Lombardo, F; Obach, RS; Waters, NJ1
Ireland, SJ; Tyers, MB1
Charney, DS; Cooney, N; Kranzler, HR; Krystal, JH; Webb, E1
Branchey, M; Buydens-Branchey, L; Fergeson, P; Hudson, J; McKernin, C3
George, FR; Kreifeldt, MJ; O'Dell, LE; Ritz, MC1
Cunningham, KA; Frankel, PS1
Hill, KP; Lee, TH; Mannelli, P; Pae, CU; Patkar, AA; Peindl, K1
Paul, LD; Roider, G; Rolf, B; Schmid, D; Staack, RF1
De Paepe, P; Devuyst, E; Kovaleva, J; Verstraete, A1
Howell, LL; Kimmel, HL; Manvich, DF1
Hermans, E; Hondebrink, L; Meulenbelt, J; Tan, S; van Kleef, RG; Westerink, RH1

Trials

3 trial(s) available for cocaine and 1-(3-chlorophenyl)piperazine

ArticleYear
Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms.
    Archives of general psychiatry, 1994, Volume: 51, Issue:11

    Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Anxiety; Blood Pressure; Cocaine; Ethanol; Hospitalization; Humans; Hydrocortisone; Male; Marijuana Abuse; Middle Aged; Piperazines; Placebos; Prolactin; Receptors, Adrenergic; Receptors, Serotonin; Substance-Related Disorders; Yohimbine

1994
Euphorogenic properties of the serotonergic partial agonist m-chlorophenylpiperazine in cocaine addicts.
    Archives of general psychiatry, 1993, Volume: 50, Issue:12

    Topics: Adult; Animals; Cocaine; Double-Blind Method; Euphoria; Humans; Piperazines; Placebos; Rats; Serotonin; Serotonin Receptor Agonists; Substance-Related Disorders

1993
Craving for cocaine in addicted users. Role of serotonergic mechanisms.
    The American journal on addictions, 1997,Winter, Volume: 6, Issue:1

    Topics: Administration, Oral; Adult; Cocaine; Humans; Male; Piperazines; Serotonin; Serotonin Receptor Agonists; Substance-Related Disorders; Synaptic Transmission

1997

Other Studies

11 other study(ies) available for cocaine and 1-(3-chlorophenyl)piperazine

ArticleYear
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve.
    British journal of pharmacology, 1987, Volume: 90, Issue:1

    Topics: Animals; Biguanides; Cocaine; In Vitro Techniques; Male; Piperazines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Vagus Nerve

1987
The meta-chlorophenylpiperazine challenge test in cocaine addicts: hormonal and psychological responses.
    Biological psychiatry, 1997, Jun-01, Volume: 41, Issue:11

    Topics: Adult; Anxiety; Cocaine; Humans; Hydrocortisone; Male; Piperazines; Prolactin; Serotonin Receptor Agonists; Substance-Related Disorders

1997
Serotonin(2C) receptors appear to mediate genetic sensitivity to cocaine-induced convulsions.
    Psychopharmacology, 1999, Volume: 146, Issue:3

    Topics: Animals; Cocaine; Male; Mice; Mice, Inbred C57BL; Piperazines; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Seizures; Species Specificity

1999
m-Chlorophenylpiperazine (mCPP) modulates the discriminative stimulus effects of cocaine through actions at the 5-HT2C receptor.
    Behavioral neuroscience, 2004, Volume: 118, Issue:1

    Topics: Animals; Cocaine; Discrimination Learning; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2004
Relationship of prolactin response to meta-chlorophenylpiperazine with severity of drug use in cocaine dependence.
    Human psychopharmacology, 2006, Volume: 21, Issue:6

    Topics: Adult; Analysis of Variance; Behavior; Biomarkers; Brain; Case-Control Studies; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Female; Humans; Male; Piperazines; Pituitary Gland, Anterior; Prolactin; Serotonin; Serotonin Receptor Agonists; Severity of Illness Index

2006
Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake: use as adulterant of cocaine resulting in drug-drug interactions?
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: Adult; Cocaine; Cytochrome P-450 CYP2D6; Drug Contamination; Drug Interactions; Female; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Phenotype; Piperazines

2007
Acute chlorophenylpiperazine overdose: a case report and review of the literature.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:3

    Topics: Acute Disease; Adult; Amphetamine; Central Nervous System Depressants; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Drug Overdose; Ethanol; Female; Humans; Piperazines; Serotonin Receptor Agonists; Tandem Mass Spectrometry

2008
Effects of serotonin 2C receptor agonists on the behavioral and neurochemical effects of cocaine in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:2

    Topics: Animals; Behavior, Animal; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Ethylamines; Indoles; Male; Microdialysis; Nucleus Accumbens; Piperazines; Receptor, Serotonin, 5-HT2C; Saimiri; Self Administration; Serotonin 5-HT2 Receptor Agonists

2012
Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse.
    Neurotoxicology, 2013, Volume: 35

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Humans; Membrane Potentials; N-Methyl-3,4-methylenedioxyamphetamine; Oocytes; Patch-Clamp Techniques; Piperazines; Receptors, GABA-A; Xenopus laevis

2013