cocaine and (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane

cocaine has been researched along with (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane in 390 studies

Research

Studies (390)

TimeframeStudies, this research(%)All Research%
pre-19908 (2.05)18.7374
1990's184 (47.18)18.2507
2000's158 (40.51)29.6817
2010's38 (9.74)24.3611
2020's2 (0.51)2.80

Authors

AuthorsStudies
D'Mello, GD; Goldberg, DM; Goldberg, SR; Stolerman, IP2
Gehlert, DR; Schoepp, DD1
Reith, ME; Selmeci, G2
Boja, JW; Carroll, FI; Kuhar, MJ; Rostène, W; Scherman, D1
Hitzemann, R; Svingos, AL1
Kaufman, MJ; Madras, BK3
Reith, ME; Wiener, HL1
Inosaka, T; Numachi, Y; Sato, M; Yoshida, S1
Boja, JW; Kuhar, MJ; Markham, L; Patel, A; Uhl, G1
Brownell, AL; Brownell, GL; Elmaleh, D; Hantraye, P; Isacson, O; Madras, BK; Spealman, RD; Wüllner, U1
Kuhar, MJ; Lew, R; Patel, A; Vaughan, RA; Wilson, A1
Boja, JW; Carroll, FI; Cline, EJ; Katz, JL; Kuhar, MJ; Scheffel, U1
Aloyo, VJ; Harvey, JA; Kirifides, AL1
Abraham, P; Boja, JW; Carroll, FI; Gao, Y; Kuhar, MJ; Lew, R; Lewin, AH; Patel, A1
Bergman, J; Madras, BK; Melia, KF; Spealman, RD1
Bergman, J; Madras, BK; Spealman, RD1
Kaufman, MJ; Madras, BK; Spealman, RD1
Kuhar, MJ; Lew, R; Simantov, R; Vaughan, RA1
Kuhar, MJ; Pögün, S; Scheffel, U1
Rudnick, G; Wall, SC1
Gregor, P; Kitayama, S; Kuhar, M; Lin, CL; Nanthakumar, E; Patel, A; Shimada, S; Uhl, G1
Abraham, P; Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Parham, K1
Madras, BK; Milius, RA; Neumeyer, JL; Saha, JK1
Boja, JW; Kuhar, MJ; Pögün, S; Scheffel, U; Stathis, M1
Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Philip, A; Rahman, MA1
Canfield, DR; Kaufman, MJ; Madras, BK; Spealman, RD1
Canfield, DR; Fahey, MA; Kamien, JB; Madras, BK; Milius, RA; Neumeyer, JL; Saha, JK; Spealman, RD1
Heikkila, RE; Nicklas, WJ; Ofori, S1
Boja, JW; Kuhar, MJ; Scheffel, U1
Fahey, MA; Madras, BK; Milius, RA; Neumeyer, JL; Saha, JK; Spealman, RD1
Heikkila, RE; Kindt, MV; Mayer, RA1
Lajtha, A; Reith, ME; Sershen, H1
Järbe, TU1
Boja, JW; Carroll, FI; Kuhar, MJ; Lever, SZ; Scheffel, U; Stathis, M1
Allen, AC; George, C; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH1
Chen, R; Ding, YS; Fowler, JS; Gatley, SJ; Sugano, Y; Volkow, ND1
Brownell, AL; Brownell, GL; Elmaleh, DR; Liang, AY; Madras, BK; Meltzer, PC1
Eshleman, AJ; Janowsky, A; Neve, KA; Neve, RL1
Kunko, PM; Maher, JR; McDowell, KP; Robinson, SE1
Boja, JW; Kopajtic, TA1
Coen, KM; Corrigall, WA; Kish, SJ; Nobrega, JN; Shannak, K; Wilson, JM1
Aloyo, VJ; Harvey, JA; Kirifides, AL; Pazdalski, PS; Ruffin, JS1
Abraham, P; Boja, JW; Cadet, JL; Carroll, FI; Kopajtic, TA; Lever, J; Lewin, AH; Seltzman, HH; Wyrick, CD1
Carney, JM; Tolliver, BK1
Gracz, LM; Madras, BK1
Heller, B; Izenwasser, S; Katz, JL; Terry, P; Witkin, JM1
London, ED; Mantione, CR; Ritz, MC1
Alexoff, DA; Chen, R; Dewey, SL; Ding, YS; Fowler, JS; Gatley, SJ; Pan, D1
Coffey, LL; Reith, ME; Xu, C3
Moriwaki, A; Uhl, GR; Wang, JB1
Eckenhoff, RG; Fagan, D1
Brownell, AL; Brownell, GL; Burns, L; Elmaleh, D; Hantraye, P; Pakzaban, P; Petto, AJ; Shoup, T; Spealman, RD; Wüllner, U1
Giovanni, A; Heikkila, RE; Sieber, BA; Sonsalla, PK1
Giovanni, A; Heikkila, RE; Sonsalla, PK1
Dohi, T; Kitayama, S; Uhl, GR1
Hearn, WL; Mash, DC; Ruttenber, AJ; Staley, JK; Wetli, CV1
Deutsch, HM; Schweri, MM1
Dutta, AK; Madras, BK; Meltzer, PC; Reith, ME1
Abraham, P; Boja, JW; Carroll, FI; Gao, Y; Kuhar, MJ; Kuzemko, MA; Lewin, AH; Mascarella, SW1
Patel, A1
Madras, BK1
Isacson, O1
Goodman, MM; Meyer, MA1
Carroll, ME; Dixon, LM; Kish, SJ; Lac, ST; Niznik, HB; Nobrega, JN; Pristupa, ZB; Shannak, K; Wilson, JM1
Coffey, LL; Reith, ME3
Campbell, AD; Erwin, VG; Jones, BC; Womer, DE1
Crippen, GM; Srivastava, S1
Chan, B; Chen, CA; Dannals, RF; Folio, T; Ravert, HT; Ricaurte, GA; Scheffel, U; Shaya, EK; Wong, DF; Yung, B1
Izenwasser, S; Katz, JL; Newman, AH1
Hoffman, BJ; Kish, SJ; Niznik, HB; Pristupa, ZB; Wilson, JM1
Carroll, FI; Clark, TB; Duncan, GE; Kirkman, JA; Little, KY1
Dannals, RF; Ehlers, MD; Frost, JJ; Ravert, HT; Reich, SG; Rosier, AJ; Smith, JS; Snyder, SH1
Becketts, KM; Carroll, FI; de Costa, BR; Dersch, CM; Radesca, LR; Rice, KC; Rothman, RB1
Hanbauer, I; Valchar, M1
Richfield, EK1
Cox, BM; Izenwasser, S; Rosenberger, JG1
Butler, T; Dobbie, JW; Duffield, R; Hjelle, JT; Ho, AK; Miller-Hjelle, MA; Reith, M; Steidley, KR1
Bergman, DA; Coulter, CL; Happe, HK; Murrin, LC1
Aloyo, VJ; Harvey, JA; Kirifides, AL; Pazdalski, PS1
Cody, V; Froimowitz, M; Patrick, KS1
Laihinen, A; Någren, K; Rinne, JO; Rinne, UK; Ruotsalainen, U; Ruottinen, H1
Blanc, G; Charnay, Y; de Saint Hilaire, Z; Gaillard, JM; Python, A1
Chen, NH; Coffey, LL; Reith, ME; Xu, C1
Kish, SJ; Wilson, JM1
Deutsch, HM; Gruszecka-Kowalik, E; Schweri, MM; Shi, Q1
Breese, GR; Bryan, RN; Dannals, RF; Evans, A; Gjedde, A; Harris, JC; Kuhar, MJ; Marenco, S; Naidu, S; Ravert, HT; Rousset, O; Wong, DF; Yaster, M; Yokoi, F1
Aronson, B; Enmon, JL; Izenwasser, S; Katz, JL; Kelkar, SV; Luo, L; Nolan, SP; Trudell, ML1
Ciliax, BJ; Lee, FJ; Levey, AI; Niznik, HB; Pristupa, ZB1
Boja, JW; Ehlers, MD; Kim, SE; Kuhar, MJ; Scheffel, U; Steinert, C1
Reith, ME; Xu, C2
Allard, P; Marcusson, JO; Ross, SB1
Abraham, P; Blough, BE; Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH1
Cox, BM; Izenwasser, S; Katz, JL; Newman, AH1
Bergman, J; Haaparanta, M; Hietala, J; Laakso, A; Solin, O1
Carroll, FI; Fleckenstein, AE; Kuhar, MJ; Pögün, S1
Abraham, P; Boja, JW; Carroll, FI; Holmquist, CR; Keverline-Frantz, KI; Kuhar, MJ1
Abraham, P; Boja, JW; Carroll, FI; Lewin, AH; Mash, DC; Seltzman, HH; Staley, JK; Wyrick, CD1
Boja, JW; Carroll, FI; Fleckenstein, AE; Kopajtic, TA; Kuhar, MJ1
Altman-Hamamdzic, S; Arnaud, P; Ma, JX; Parratto, NP; Sallee, FR; Vrindavanam, NS1
Alpert, NM; Babich, JW; Bonab, AA; Christian, BT; Fischman, AJ; Hsu, H; Livni, E; Madras, BK; Morris, ED; Weise, S1
Flores, G; Liang, JJ; Quirion, R; Srivastava, LK; Wood, GK1
Darmani, NA; Reeves, SL1
Boja, JW; Houlihan, WJ; Kopajtic, TA; Kuhar, MJ; Parrino, VA1
Apostolakis, EM; Clark, JH; Garai, J; O'Malley, BW1
Brownell, AL; Brownell, GL; Elmaleh, DR; Fischman, AJ; Madras, BK; Meltzer, PC; Shoup, TM1
Byon, C; Elmaleh, DR; Fischman, AJ; Hanson, RN; Liang, AY; Madras, BK; Meltzer, PC; Shoup, TM1
Reith, ME; Zhang, L1
Glowa, JR; Wojnicki, FH1
Halldin, C; Lehikoinen, P; Müller, L; Någren, K; Swahn, CG1
Coffey, LL; Dutta, AK; Reith, ME1
Descarries, L; Doucet, G; Lafaille, F; Mrini, A; Soucy, JP1
Bowen, WD; Izenwasser, S; Joseph, DB; Katz, JL; Kline, RH; Newman, AH1
Izenwasser, S; Katz, JL; Kelkar, SV; Kline, RH; Lomenzo, SA; Trudell, ML; Xu, L1
Chang, LJ; el-Awar, M; Guttman, M; Kish, SJ; Levey, AI; Robitaille, Y1
Coffey, LL; Reith, ME; Zhang, L1
Avor, KS; Basmadjian, GP; Pouw, B; Seale, TW; Singh, S1
Coffey, LL; Reith, ME; Wu, Q1
Ding, YS; Fowler, JS; Gatley, SJ; Volkow, ND; Wang, GJ1
Gjedde, A; Gründer, G; Harris, J; Kuhar, M; Naidu, S; Ricaurte, G; Rothman, R; Singer, H; Szymanski, S; Villemagne, V; Wong, DF; Yokoi, F1
Jackson, PF; Olkowski, JL; Slusher, BS; Tiffany, CW1
Ashworth, S; Brown, DJ; Hirani, E; Hume, SP; Lammertsma, AA; Luthra, SK1
Beal, MF; Bogdanov, M; Brownell, AL; Chen, YC; Galpern, WR; Isacson, O; Jenkins, BG; Keltner, JR; Matthews, RT; Rosen, BR1
Izenwasser, S; Kunko, PM; Loeloff, RJ1
Dannals, RF; Hatzidimitriou, G; Mathews, WB; McCann, UD; Musachio, J; Ravert, HT; Ricaurte, GA; Villemagne, V; Wong, DF; Yuan, J1
Cunningham, VJ; Gunn, RN; Hume, SP; Lammertsma, AA1
Avor, K; Basmadjian, GP; Chan, HM; Hall, N; Seale, TW; Singh, S1
Geter-Douglass, B; Tirelli, E; Witkin, JM1
Agoston, GE; George, C; Izenwasser, S; Katz, J; Kline, RH; Newman, AH; Wu, JH1
Bowen, WD; Husbands, SM; Izenwasser, S; Katz, JL; Loeloff, RJ; Newman, AH; Vilner, BJ1
Izenwasser, S; Katz, JL; Klein, CL; Lomenzo, SA; Terry, PD; Trudell, ML; Zhu, N1
Lehikoinen, P; Någren, K; Rinne, JO; Ruottinen, H; Sahlberg, N1
Ding, YS; Fowler, JS; Gatley, SJ; King, P; Logan, J; Pappas, N; Volkow, ND; Wang, GJ1
Abraham, P; Boja, JW; Burgess, JP; Carroll, FI; Keverline-Frantz, KI; Kuhar, MJ; Lewin, AH1
Coulter, CL; Happe, HK; Murrin, LC1
Gunn, RN; Hume, SP; Jones, T1
Bergman, J; Haaparanta, M; Hietala, J; Laakso, A; Solin, O; Vilkman, H1
Allard, P; Norlén, M1
Babich, J; Elmaleh, DR; Fischman, AJ; Liang, AY; Madras, BK; Meltzer, PC1
Araldi, GL; Boja, J; Flippen-Anderson, JL; George, C; Johnson, KM; Kozikowski, AP; Meil, WM; Saiah, E1
Izenwasser, S; Katz, JL; Terry, PD; Trudell, ML; Zhang, C1
Frederiksen, D; Gether, U; Nielsen, EO; Norregaard, L1
Ferrer, JV; Javitch, JA1
Dutta, AK; Reith, ME; Xu, C1
Lee, FJ; Liu, F; Man, HY; McConkey, F; Niznik, HB; Pristupa, ZB; Wang, YT1
Elmer, LW; Little, KY; Zhang, L1
Dannals, RF; McCann, UD; Ricaurte, GA; Villemagne, V; Wong, DF; Yokoi, F1
Bonnet, JJ; Corera, AT; Do Régo, JC1
Carroll, FI; Chen, NH; Reith, ME; Xu, C1
Berger, R; Brust, P; Hoepping, A; Johannsen, B; Leibnitz, P; Machill, S; Scheller, D; Spies, H1
Allen, AC; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH1
Fleckenstein, AE; Hanson, GR; Kokoshka, JM; Vaughan, RA1
Harvey, DC; Huang, SC; Lacan, G; Melega, WP; Phelps, ME1
Dickinson, SD; Gerhardt, GA; Giardina, K; Grandy, DK; Kelly, MA; Larson, GA; Low, MJ; Rubinstein, M; Sabeti, J; Zahniser, NR1
Brashear, A; Farlow, MR; Hutchins, GD; Mulholland, GK; Siemers, ER; Zheng, QH1
Berfield, JL; Reith, ME; Wang, LC1
Cassin, BJ; Dalack, GW; Desmond, T; Frey, KA; Little, KY; Zhang, L1
Bergman, J; Eronen, E; Haaparanta, M; Oikonen, V; Rinne, JO; Ruottinen, H; Solin, O; Sonninen, P1
Gerhardt, GA; Hebert, MA; Larson, GA; Zahniser, NR1
Li, LB; Reith, ME2
Deutsch, H; Schenk, JO; Schweri, MM; Wayment, HK1
Burnham, KS; Collard, DM; Deshpande, AK; Deutsch, HM; Holtzman, SG; Schweri, MM; Zhang, L1
Chang, AS; Chang, SM1
Dannals, RF; Matecka, D; Rice, KC; Rothman, RB; Villemagne, VL; Wong, DF; Yokoi, F1
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M1
Dresel, SH; Hou, C; Huang, XF; Kung, HF; Kung, MP; Meegalla, SK; Mu, M; Patselas, G; Plössl, K; Saffer, JR1
Dannals, RF; Frost, JJ; Ilgin, N; Ravert, HT; Reich, SG; Zubieta, J1
Futatsubashi, M; Iyo, M; Okada, H; Ouchi, Y; Sakamoto, M; Sekine, Y; Yoshikawa, E1
Guilarte, TR; Kuhlmann, AC1
Brownell, AL; Isacson, O; Jenkins, BG1
Corera, AT; Costentin, J; Deslandes, A; Vaugeois, JM1
Belej, T; Gernert, M; Löscher, W; Nobrega, JN; Raymond, R; Richter, A1
Dewar, KM; Paquet, M; Sequeira, A1
Carroll, FI; Garrett, BE; Hunter, RG; Kuhar, MJ; Lambert, PD; McGirr, KM1
Izenwasser, S; Kline, RH; Newman, AH; Robarge, MJ1
Chen, A; Cumming, P; Dagher, A; Deep, P; Gjedde, A; Kapczinski, F; Reutens, D; Wong, DF; Yokoi, F1
Beal, MF; Bogdanov, M; Brownell, AL; Chen, YI; Galpern, W; Isacson, O; Jenkins, BG; Livni, E; Rosen, BR1
Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Sakamoto, M; Torizuka, T; Yoshikawa, E1
Dewar, KM1
Collard, DM; Deutsch, HM; Javanmard, S; Kuhar, MJ; Schweri, MM1
Harada, N; Kakiuchi, T; Nakanishi, S; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H1
Gether, U; Loland, CJ; Norregaard, L3
Blundell, P; Gonzalez, MD; Liang, AY; Madras, BK; Meltzer, PC; Niznik, HB; Pristupa, ZB1
Desalles, AA; Lacan, G; Melega, WP; Phelps, ME1
Berciano, J; Figols, J; González, AM; Pascual, J; Pazos, A1
Izenwasser, S; Katz, JL; Terry, P1
Alakare, B; Bergman, J; Haaparanta, M; Hietala, J; Laakso, A; Peurasaari, J; Räkköläinen, V; Solin, O; Syvälahti, E; Vilkman, H1
Bergman, J; Hietala, J; Kajander, J; Laakso, A; paranta, M; Solin, O; Vilkman, H1
Futatsubashi, M; Homma, Y; Ishii, SI; Ishiwata, K; Kawamura, K; Ouchi, Y; Senda, M1
Brownell, AL; Cavagna, F; Coyle, JT; Iris Chen, YC; Jenkins, BG; Livni, E; Nguyen, TV; Rosen, BR1
Barrio, JR; Huang, SC; Namavari, M; Nguyen, Q; Petric, A; Satyamurthy, N; Stout, D1
Carroll, FI; Kimmel, HL; Kuhar, MJ1
Blundell, P; Huang, H; Liu, S; Madras, BK; Meltzer, PC; Yong, YF1
Itokawa, M; Lin, Z; Uhl, GR1
German, DC; Hogan, KA; Liang, CL; Sonsalla, PK; Staal, RG1
Callahan, B; Hatzidimitriou, G; Kim, S; Ricaurte, GA; Westphalen, R; Yuan, J1
Chang, MY; Chin, HR; Lee, KH; Lee, SH; Lee, YS; Park, BS1
Cai, NS; Itokawa, M; Kitayama, S; Lin, Z; Uhl, GR; Wang, JB; Wu, C1
Bergman, J; Haaparanta, M; Kaasinen, V; Nurmi, E; Rinne, JO; Ruottinen, HM; Solin, O1
Stoessl, AJ; Van Kampen, JM1
Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H1
McGeer, EG; Stoessl, AJ; Van Kampen, JM1
Partridge, B; Schenk, S; Shippenberg, TS1
Davidson, C; Douglas, SB; Ellinwood, EH; Lee, TH1
Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Tsukada, H1
Bonnet, JJ; Corera, AT; Costentin, J1
Berfield, JL; Carroll, FI; Kuhar, MJ; Reith, ME; Wang, LC1
Dannals, RF; Hilton, J; Ravert, HT; Szabo, Z; Wong, DF; Yokoi, F1
Bergman, J; Eskola, O; Hinkka, SM; Nurmi, E; Rinne, JO; Solin, O; Sonninen, P1
Araujo, DM; Cherry, SR; Kornblum, HI; Tatsukawa, KJ; Toyokuni, T1
Lin, Z; Uhl, GR; Wang, W1
Mayfield, RD; Zahniser, NR1
Fleckenstein, AE; Hanson, GR; Riddle, EL; Sandoval, V; Ugarte, YV1
Dutta, AK; Madras, BK; Reith, ME1
Ferrer, JV; Javitch, JA; Justice, JB; Whitehead, RE1
Doolen, S; Zahniser, NR1
Bonnet, JJ; Costentin, J; Do-Régo, JC; Tidjane Corera, A1
Hansen, SH; Jensen, AG; Nielsen, EO1
Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Tanaka, K; Torizuka, T; Yoshikawa, E1
Bergman, J; Eskola, O; Nurmi, E; Rinne, OJ; Ruottinen, HM; Solin, O1
Friedman, DP; Letchworth, SR; Nader, MA; Porrino, LJ; Smith, HR1
Agoston, GE; Alling, KL; Forster, MJ; Katz, JL; Kline, RH; Kopajtic, TA; Newman, AH; Woolverton, WL1
Kimmel, H; Kuhar, MJ; Vicentic, A1
Chen, N; Reith, ME; Vaughan, RA1
Kida, T; Suzuki, K; Takei, M1
Berfield, JL; Ferrer, JV; Javitch, JA; Reith, ME; Wang, LC1
Deutsch, HM; Liu, Z; Schweri, MM; Shi, Q; Ye, X1
Futatsubashi, M; Iyo, M; Matsunaga, T; Mori, N; Okada, H; Ouchi, Y; Sekine, Y; Takei, N; Tsukada, H; Yoshikawa, E1
Balu, R; Davidson, C; Ellinwood, EH; Lee, TH1
Davis, MC; Dutta, AK; Reith, ME1
Cui, D; Ding, J; Fei, J; Guo, L; Liu, Z; Mei, Z; Wang, Y; Zhao, W1
Stavale, JN; Villares, JC1
Bergman, J; Haaparanta, M; Hietala, J; Laakso, A; Solin, O; Syvälahti, E; Vilkman, H1
Avor, KS; Basmadjian, GP; el-Moselhy, TF1
Chi, DY; Chung, KH; Jin, C; Lee, DR; Lim, CH1
Cao, J; Husbands, SM; Katz, JL; Kopajtic, T; Newman, AH1
Justice, JB; Katz, JL; Kopajtic, T; Newman, AH; Wirtz, S; Zou, MF1
Keller, D; Maiya, R; Mayfield, RD; Zahniser, NR1
Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H1
Elmer, LW; Little, KY; Scheys, JO; Zhang, L; Zhong, H1
Brown, JM; Fleckenstein, AE; Gibb, JW; Hansen, JP; Hanson, GR; Riddle, EL; Sandoval, V1
Schenk, S1
Boksa, P; El-Khodor, BF1
Lin, Z; Uhl, GR2
Cui, XN; Li, LB; Reith, MA1
Chang, MY; Jeon, DJ; Lee, CH; Lee, SH; Lee, YS; Oh, DY; Son, H1
Hearn, WL; Izenwasser, S; Mash, DC; Ouyang, Q; Pablo, J1
Enyedy, IJ; Johnson, KM; Wang, J; Wang, S; Zaman, WA1
Chen, N; Reith, ME; Sun, L1
Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H1
Chen, JC; Hwang, JJ; Liao, MH; Lin, KJ; Pan, WH; Ting, G; Wey, SP; Yen, TC1
Gittings, D; Schenk, S1
Fleckenstein, AE; Hanson, GR; Rau, KS; Riddle, EL; Topham, MK1
Houlihan, WJ; Kelly, L1
France, CP; Frazer, A; Galici, R; Galli, A; Gould, GG; Jones, DJ; Lin, RZ; Sanchez, TA; Saunders, C1
Ishiwata, K; Kawamura, K; Oda, K1
Chen, N; Reith, ME; Rickey, J1
Cho, AK; Kuczenski, R; Melega, WP; O'Neil, ML; Segal, DS1
De Montis, MG; Grappi, S; Leggio, B; Masi, F; Nanni, G; Rauggi, R; Scheggi, S1
Gulley, JM; Hoover, BR; Larson, GA; Zahniser, NR1
Futatsubashi, M; Iyo, M; Minabe, Y; Mori, N; Nakamura, K; Okada, H; Ouchi, Y; Sekine, Y; Suzuki, K; Takei, N; Tsukada, H; Yoshikawa, E1
Helenius, H; Hublin, C; Någren, K; Partinen, M; Rinne, JO1
Chen, N; Cui, XN; Reith, ME; Wang, LC1
Appell, M; Berfield, JL; Chen, N; Dunn, WJ; Reith, ME; Wang, LC1
Buesing, WR; Norman, AB; Norman, MK; Tabet, MR; Tsibulsky, VL1
Agoston, GE; Katz, JL; Kopajtic, TA; Newman, AH1
Brake, WG; Diorio, J; Gratton, A; Meaney, MJ; Zhang, TY1
Chen, N; Reith, ME; Zhen, J2
Ordway, GA; Wee, S; Woolverton, WL1
Gulley, JM; Hanania, T; Larson, GA; Salaz, DO; Zahniser, NR1
Brownell, AL; McNaught, KS; Olanow, CW; Perl, DP1
Becker, KG; Cheadle, C; Donovan, DM; McCann, UD; Mechan, AO; Ricaurte, GA; Tong, L; Xie, T; Yuan, J1
Brownell, AL; Chen, YC; Isacson, O; Jenkins, BG; Sanchez-Pernaute, R1
Madras, BK; Meltzer, PC; Pham-Huu, DP1
Chen, N; Dutta, AK; Maiti, S; Reith, ME; Zhen, J1
Arias-Montaño, JA; Díaz-Romero, M; Eguibar, JR; Flores, G1
Mock, BH; Zheng, QH1
Andersen, ML; Hipólide, DC; Nobrega, JN; Papale, LA; Tufik, S1
Herndon, JG; Killiany, RJ; Luebke, JI; Moore, TL; Moss, MB; Rosene, DL; Schettler, SP1
Bondi, CD; Kozikowski, AP; Kulkarni, SS; Newman, AH; Pan, S; Surratt, CK; Ukairo, OT1
Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Tsukada, H1
Campbell, VC; Katz, JL; Kopajtic, TA; Newman, AH1
Furman, CA; Gnegy, ME; Guptaroy, B; Johnson, LA; Zhang, M1
Adams, RJ; Alexander, M; Chen, MK; Furukawa, E; Guilarte, TR; Lee, JS; McGlothan, JL; Wong, DF1
Aksenov, MY; Aksenova, MV; Booze, RM; Mactutus, CF; Nath, A; Ray, PD; Silvers, JM1
Dutta, AK; Reith, ME; Zhang, S; Zhen, J1
Bugert, P; Deuschle, M; Frankhauser, P; Grimmer, Y; Schloss, P; Schmidt, M1
Dar, DE; Metzger, TG; Uhl, GR; Vandenbergh, DJ1
Bottoncetti, A; Cini, N; Danieli, E; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A1
Ben-Shahar, O; Ettenberg, A; Moscarello, JM1
Andren, PE; Svenningsson, P; Zhang, X1
Baroni, S; Betti, L; Cassano, GB; Catena, M; Dell'Osso, B; Fabbrini, L; Giannaccini, G; Italiani, P; Lucacchini, A; Marazziti, D1
Bendor, J; Bonab, AA; Elmaleh, DR; Fahey, MA; Fischman, AJ; Goodrich, C; Goulet, M; Lin, Z; Livni, E; Madras, BK; Meltzer, PC1
Cho, AK; Kuczenski, R; Lacan, G; Melega, WP; O'Neil, ML; Segal, DS1
Camarasa, J; Chipana, C; Escubedo, E; Pubill, D1
Kanno, T; Nakayama, T; Ouchi, Y; Shinke, T; Torizuka, T; Yoshikawa, E1
Deschamps, JR; Liu, S; Madras, BK; Meltzer, PC; Pham-Huu, DP1
Hattori, N; Ida, H; Kono, S; Miyajima, H; Mizuno, Y; Ouchi, Y; Sakamoto, M; Shirakawa, K; Sugiura, T; Suzuki, H; Takahashi, Y; Tomiyama, H1
Daws, LC; Frazer, A; Giuffrida, A; Gould, GG; Owens, WA; Price, DA; Roberts, JL1
Di Monte, DA; Guillot, TS; Hatcher, JM; Jones, DP; McCormack, AL; Miller, GW; Pennell, KD; Richardson, JR1
Brownell, AL; Wang, JQ; Wang, X; Yu, M; Zhu, A1
Deutsch, HM; Kim, DI; Schweri, MM; Ye, X1
Bohnen, NI; Constantine, GM; Gedela, S; Kuwabara, H; Mathis, CA; Moore, RY; Studenski, SA1
Fei, J; Guo, LH; Li, S; Qin, GW; Zhao, G1
Brownell, AL; Cicchetti, F; Pellegrino, D; Saint-Pierre, M; Wang, X; Yu, M; Zhu, A1
Cepeda, IL; Cornfeldt, ML; Doudet, DJ; Flores, J; O'Kusky, JR1
Cho, AK; Fairbanks, LA; Jorgensen, MJ; Laćan, G; Melega, WP; Morton, G; Pham, J; Way, BM1
Bardo, MT; Bruntz, RC; Dwoskin, LP; Stairs, DJ; Zhu, J1
Bohnen, NI; Constantine, GM; Kuwabara, H; Mathis, CA; Moore, RY1
Lee, FJ; Liu, F; Moszczynska, A; Saleh, J; Vukusic, B; Zhang, H1
Cao, J; Desai, RI; Gerstbrein, K; Gether, U; Grundt, P; Katz, JL; Loland, CJ; Newman, AH; Sitte, HH; Zou, MF1
Adams, RJ; Alexander, M; Brasić, JR; Burton, NC; Chen, MK; Guilarte, TR; Kumar, A; Kuwabara, H; McGlothan, JL; Verina, T; Wong, DF; Zhou, Y1
Abbey, R; Alexander, M; Brasic, J; Dannals, RF; Kumar, A; Kuwabara, H; McCann, UD; Palermo, M; Ricaurte, GA; Wong, DF; Ye, W1
Baroni, S; Betti, L; Catena Dell'Osso, M; Dell'osso, B; Fabbrini, L; Giannaccini, G; Lucacchini, A; Marazziti, D; Masala, I1
Deng, C; du Bois, TM; Hsu, CW; Huang, XF; Li, Y; Tan, YY1
Fagerholm, V; Grönroos, T; Haaparanta, M; Koivula, T; Lipponen, T; Marjamäki, P; Perhola, O; Solin, O; Vepsäläinen, J1
Bergmann, ML; Beuming, T; Gether, U; Gracia, L; Javitch, JA; Kniazeff, J; Loland, CJ; Newman, AH; Raniszewska, K; Shi, L; Weinstein, H1
Aksenov, MY; Aksenova, MV; Booze, RM; Mactutus, CF; Silvers, JM1
Ambrosio, E; Crespo, JA; Del Olmo, N; García-Lecumberri, C; Higuera-Matas, A; Miguéns, M; Montoya, GL1
Beveridge, TJ; Nader, MA; Porrino, LJ; Smith, HR1
Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J1
Bohnen, NI; Constantine, GM; Gedela, S; Herath, P; Moore, RY1
Berger, ML; Pifl, C; Rebernik, P; Reither, H; Wolf, A1
Amable, R; Chen, J; Freed, WJ; Gabitzsch, E; Lee, CT; Lupica, CR; Spivak, CE; Vazin, T1
Ishibashi, K; Ishii, K; Ishiwata, K; Kawasaki, K; Mizusawa, H; Oda, K1
Kritzer, MF; Meyers, B1
Fei, X; Gitter, BD; Hutchins, GD; Mock, BH; Territo, PR; Winkle, WL; Yoder, KK; Zheng, QH1
Cassin, B; Little, KY; Ramssen, E; Roland, CJ; Volberg, V; Welchko, R1
Iida, A; Inoue, N; Kakiuchi, T; Kondo, Y; Muramatsu, S; Nakano, I; Nakayama, T; Okuno, T; Ono, F; Suzuki, Y; Takino, N; Terao, K; Tsukada, H1
Gai, Y; Guo, LH; Jiang, ZH; Qin, GW; Zhao, G; Zheng, XW1
Booze, RM; Mactutus, CF; Wallace, DR; Zhu, J1
Cha, JH; Eriksen, J; Gether, U; Newman, AH; Rasmussen, SG; Rasmussen, TN; Vaegter, CB; Zou, MF1
Ebbs, AL; Green, JL; Katz, JL; Newman, AH; Tallarida, RJ; Tanda, G; Tronci, V1
Farrer, MJ; Hattori, N; Imai, H; Inoue, Y; Ishii, K; Ishiwata, K; Kachergus, JM; Kitagawa, M; Kono, S; Mizoguchi, K; Mizuno, Y; Nishioka, K; Obi, T; Ross, OA; Takanashi, M1
Price, DA; Sorkin, A; Zahniser, NR1
Cui, XX; Guo, JF; Jiang, H; Lei, LF; Long, ZG; Pan, Q; Shen, L; Song, XW; Tang, BS; Wang, JL; Xia, K; Xiao, B; Yan, XX1
Jia, J; Li, B; Liu, L; Sun, Z; Tian, J; Wang, X; Wang, Y; Zhang, J1
Hiranita, T; Katz, JL; Soto, PL; Tanda, G1
Baroni, S; Betti, L; Catena Dell'osso, M; Consoli, G; Dell'Osso, B; Giannaccini, G; Lucacchini, A; Marazziti, D; Masala, I1
Hayashi, T; Saiki, H; Takahashi, J; Takahashi, R1
Futatsubashi, M; Ouchi, Y; Torizuka, T; Yagi, S; Yokokura, M; Yoshihara, Y; Yoshikawa, E1
Donovan, DM; Katz, JL; Kopajtic, TA; Liu, Y; Newman, AH; Surratt, CK1
Abad, S; Camarasa, J; Escubedo, E; Pubill, D; Torres, I1
Desai, A; Fraser, R; Gnegy, ME; Guptaroy, B; Zhang, M1
Bardo, MT; Booze, RM; Dwoskin, LP; Gomez, AM; Mactutus, CF; Midde, NM; Wooters, TE; Zhu, J1
Cao, L; Guo, QY; Wang, XM; Wang, XY; Zhang, YF1
Albrecht, D; Anand, A; Barkay, G; Dzemidzic, M; Hutchins, GD; Karne, H; Normandin, MD; Yoder, KK; Zheng, QH1
Cao, J; Hiranita, T; Katz, JL; Kohut, SJ; Kopajtic, T; Newman, AH; Soto, PL; Tanda, G1
Ali, S; Dutta, AK; Reith, ME; Zhen, J1
Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G1
Madras, BK; Meltzer, PC; Torun, L1
Huang, T; Liang, X; Shi, X; Tang, G; Wang, H; Zhang, X1
Fujimoto, M; Konishi, T; Kono, S; Matsushita, K; Miyajima, H; Ouchi, Y; Terada, T1
Akamine, S; Asakawa, T; Mizuma, H; Namba, H; Onoe, H; Shukuri, M; Sugiyama, K; Tsukada, H; Yokoyama, C1
Deng, H; Huang, T; Liang, X; Tang, G; Wang, H; Yi, C; Zhang, X1
Liu, S; Shen, L; Tian, ZM; Wang, RM; Wieman, J; Yan, Y; Yin, F; Zhao, QJ1
Agarwal, P; Dinelle, K; Hayflick, S; Heffernan, N; Hogarth, P; Kuriakose, R; MacLeod, P; McKenzie, J; Sossi, V; Stoessl, AJ1
Brown, CA; Flores, HP; Karimi, M; Loftin, SK; Moerlein, SM; Perlmutter, JS; Tian, L; Videen, TO1
Rao, A; Sorkin, A; Zahniser, NR1
Domino, EF; Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Tsukada, H; Yamamoto, S1
Andersson, PL; Fonnum, F; Stenberg, M; Walaas, SI; Wigestrand, MB1
Gong, X; Liang, X; Liu, L; Wang, X; Zhang, W1
Chen, HX; Gao, N; Jin, ZL; Li, XR; Li, YF; Tang, Y; Xiong, J; Zhang, JR1
Brown, CA; Karimi, M; Loftin, SK; Perlmutter, JS; Tian, L1
Ali, S; Antonio, T; Cheng, SY; Jones, KT; Reith, ME; Zhen, J1
Huang, X; Midde, NM; Quizon, PM; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J1
Ananthan, S; Baumann, MH; Moukha-Chafiq, O; Partilla, JS; Pathak, V; Rothman, RB; Saini, SK1
Gomez, AM; Midde, NM; Quizon, PM; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J1
Ding, ZT; Ge, JJ; Huang, SF; Liu, SY; Wang, J; Wang, YX; Wu, JJ; Wu, P; Zhao, J; Zuo, CT1
Chen, T; Chen, Y; Guo, Z; Wang, R; Xu, B; Zhang, J; Zhu, H1
Ananth, M; Hadjiargyrou, M; Komatsu, DE; Robison, LS; Thanos, PK1
Gross, JD; Kaski, SW; Schroer, AB; Setola, V; Siderovski, DP; Wix, KA1
Chen, T; Fu, LP; Gao, ZB; Wang, W; Wang, ZF; Xu, BX; Zhao, XL1
Gnegy, ME; Guptaroy, B; Jones, KT; Mikelman, SR; Reith, MEA; Schmitt, KC; Zhen, J1
Chen, Y; Lian, Y; Wang, C; Wang, R; Zhang, Y1
Li, X; Li, Y; Mutaerbieke, N; Qin, Y; Yibulayin, A; Zhang, Q; Zhao, X1
Baird, TR; Carroll, FI; Eltit, JM; Karin, KN; Marsh, SA; Medina-Contreras, JML; Negus, SS1

Reviews

1 review(s) available for cocaine and (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Positron emission tomography of cocaine binding sites on the dopamine transporter.
    NIDA research monograph, 1994, Volume: 138

    Topics: Animals; Binding Sites; Brain; Cocaine; Dopamine; Tissue Distribution; Tomography, Emission-Computed

1994

Trials

5 trial(s) available for cocaine and (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Reproducibility and effect of levodopa on dopamine transporter function measurements: a [18F]CFT PET study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:11

    Topics: Adult; Aged; Antiparkinson Agents; Biological Transport; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reproducibility of Results; Tomography, Emission-Computed

2000
Changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in Parkinson's disease.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 4

    Topics: Aged; Arteries; Blood Pressure; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Gait; Gyrus Cinguli; Heart Rate; Humans; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Substantia Nigra; Tomography, Emission-Computed; Walking

2001
The influence of residual nor-β-CFT in 11C CFT injection on the Parkinson disease diagnosis: a 11C CFT PET study.
    Clinical nuclear medicine, 2012, Volume: 37, Issue:8

    Topics: Carbon Radioisotopes; Cocaine; Drug Residues; Female; Fluorodeoxyglucose F18; Humans; Injections, Intravenous; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography

2012
Human radiation dose estimation of (11)C-CFT using whole-body PET.
    Clinical nuclear medicine, 2012, Volume: 37, Issue:12

    Topics: Cocaine; Female; Humans; Injections, Intravenous; Male; Middle Aged; Positron-Emission Tomography; Radiation Dosage; Radiometry; Whole Body Imaging

2012
Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:12

    Topics: Aged; Aged, 80 and over; Antigens, CD; Bucladesine; Carbon Isotopes; Cell Differentiation; Cells, Cultured; Cocaine; Dopamine Uptake Inhibitors; Female; Fetus; Flow Cytometry; Growth Substances; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neural Stem Cells; Neurons; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Positron-Emission Tomography; Retinal Pigment Epithelium; Severity of Illness Index; Time Factors; Treatment Outcome; Tretinoin

2012

Other Studies

384 other study(ies) available for cocaine and (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Conditioned taste aversion and operant behaviour in rats: effects of cocaine and a cocaine analogue (WIN 35,428).
    Neuropharmacology, 1979, Volume: 18, Issue:12

    Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Rats

1979
Striatal quinolinic acid lesions increase [3H]WIN 35,428 binding to the dopamine transporter.
    Neurochemistry international, 1992, Volume: 21, Issue:4

    Topics: Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Huntington Disease; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Quinolinic Acid; Rats; Rats, Sprague-Dawley

1992
Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Aging; Animals; Apomorphine; Cocaine; Corpus Striatum; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Receptors, Dopamine; Receptors, Opioid

1992
Dopamine transport: pharmacological distinction between the synaptic membrane and the vesicular transporter in rat striatum.
    European journal of pharmacology, 1992, Jul-21, Volume: 218, Issue:1

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Synaptic Membranes; Synaptic Vesicles; Tetrabenazine

1992
5-HT3 receptor antagonists block cocaine-induced locomotion via a PCPA-sensitive mechanism.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dose-Response Relationship, Drug; Fenclonine; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Tropanes; Tropisetron

1992
Distribution of cocaine recognition sites in monkey brain: II. Ex vivo autoradiography with [3H]CFT and [125I]RTI-55.
    Synapse (New York, N.Y.), 1992, Volume: 12, Issue:2

    Topics: Animals; Autoradiography; Binding Sites; Brain; Caudate Nucleus; Cocaine; Iodine Radioisotopes; Putamen; Saimiri; Tissue Distribution; Tritium

1992
Determination of radioligand specific activity using competition binding assays.
    Analytical biochemistry, 1992, Nov-15, Volume: 207, Issue:1

    Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Female; Kinetics; Ligands; Male; Mice; Mice, Inbred C57BL; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tritium

1992
Changes of drug biodistribution in the methamphetamine sensitized rat brain.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Amphetamines; Animals; Brain; Cocaine; Iofetamine; Male; Methamphetamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Tissue Distribution

1992
Expression of a single dopamine transporter cDNA can confer two cocaine binding sites.
    Neuroreport, 1992, Volume: 3, Issue:3

    Topics: Animals; Binding Sites; Carrier Proteins; Cell Line; Cloning, Molecular; Cocaine; Corpus Striatum; DNA; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Radioligand Assay; Rats; Receptors, Drug

1992
Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism.
    Neuroreport, 1992, Volume: 3, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cocaine; Disease Models, Animal; Dopamine; Immunohistochemistry; Macaca fascicularis; Motor Activity; Nerve Fibers; Parkinson Disease, Secondary; Radioligand Assay; Tomography, Emission-Computed

1992
Microheterogeneity of dopamine transporters in rat striatum and nucleus accumbens.
    Brain research, 1992, Jul-03, Volume: 584, Issue:1-2

    Topics: Animals; Azides; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Electrophoresis, Polyacrylamide Gel; Glycoside Hydrolases; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Neuraminidase; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains

1992
Behavioral effects of novel cocaine analogs: a comparison with in vivo receptor binding potency.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins

1992
The low affinity binding site for the cocaine analog, WIN 35,428 is an artifact of freezing caudate tissue.
    Life sciences, 1992, Volume: 50, Issue:17

    Topics: Animals; Artifacts; Binding Sites; Caudate Nucleus; Cocaine; Cryopreservation; Kinetics; Male; Rabbits; Rats; Rats, Inbred Strains

1992
Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.
    Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, Drug

1992
Radiolabeling of dopamine uptake sites in mouse striatum: comparison of binding sites for cocaine, mazindol, and GBR 12935.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:3

    Topics: Animals; Binding Sites; Buffers; Cocaine; Corpus Striatum; Dopamine; Drug Interactions; Ethylmaleimide; Kinetics; Male; Mazindol; Membranes; Mice; Mice, Inbred BALB C; Phosphates; Piperazines; Radioligand Assay; Temperature; Tritium; Tromethamine

1992
Discriminative stimulus effects of cocaine in squirrel monkeys: involvement of dopamine receptor subtypes.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Dopamine Agents; Dopamine Antagonists; Levodopa; Male; Oxazines; Receptors, Dopamine; Saimiri; Time Factors

1991
Self-administration of the high-affinity cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:4

    Topics: Animals; Carrier Proteins; Cocaine; Receptors, Drug; Reinforcement Schedule; Saimiri; Self Administration

1991
Distribution of cocaine recognition sites in monkey brain: I. In vitro autoradiography with [3H]CFT.
    Synapse (New York, N.Y.), 1991, Volume: 9, Issue:3

    Topics: Animals; Autoradiography; Binding Sites; Brain; Carrier Proteins; Cocaine; Female; Male; Receptors, Drug; Saimiri; Tissue Distribution; Tritium

1991
A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428.
    Journal of neuroscience methods, 1991, Volume: 40, Issue:1

    Topics: Adsorption; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Caudate Nucleus; Centrifugation; Charcoal; Cocaine; Dogs; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Indicators and Reagents; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Stereoisomerism

1991
Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum.
    Synapse (New York, N.Y.), 1991, Volume: 9, Issue:1

    Topics: Aged; Autoradiography; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Humans; Parkinson Disease; Putamen; Receptors, Drug; Reference Values; Tritium

1991
Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909.
    European journal of pharmacology, 1991, Jun-06, Volume: 198, Issue:2-3

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Injections, Intravenous; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Piperazines; Radioimmunoassay; Receptors, Drug

1991
Binding of the cocaine analog 2 beta-[3H] carboxymethoxy-3 beta-(4-fluorophenyl)tropane to the serotonin transporter.
    Molecular pharmacology, 1991, Volume: 40, Issue:3

    Topics: Biological Transport; Blood Proteins; Carrier Proteins; Chlorides; Cocaine; Humans; Hydrogen-Ion Concentration; Imipramine; Potassium; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium

1991
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA.
    Science (New York, N.Y.), 1991, Oct-25, Volume: 254, Issue:5031

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cell Line; Cell Membrane; Cloning, Molecular; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Models, Structural; Molecular Sequence Data; Nerve Tissue Proteins; Oligodeoxyribonucleotides; Oocytes; Plasmids; Polymerase Chain Reaction; Protein Conformation; Rats; RNA, Messenger; Transcription, Genetic; Transfection; Xenopus

1991
Synthesis and ligand binding of cocaine isomers at the cocaine receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cell Membrane; Chemical Phenomena; Chemistry; Cocaine; Corpus Striatum; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Drug; Stereoisomerism

1991
Synthesis and receptor binding of N-substituted tropane derivatives. High-affinity ligands for the cocaine receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Animals; Binding Sites; Carrier Proteins; Chemical Phenomena; Chemistry; Cocaine; Female; Macaca fascicularis; Male; Receptors, Drug; Structure-Activity Relationship; Tritium; Tropanes

1991
In vivo labeling of cocaine binding sites on dopamine transporters with [3H]WIN 35,428.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Radioligand Assay; Receptors, Drug; Tissue Distribution

1991
New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
    European journal of pharmacology, 1990, Aug-10, Volume: 184, Issue:2-3

    Topics: Animals; Binding, Competitive; Biological Transport; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Radioligand Assay; Rats; Synaptosomes

1990
Autoradiographic localization of cocaine binding sites by [3H]CFT ([3H]WIN 35,428) in the monkey brain.
    Synapse (New York, N.Y.), 1990, Volume: 6, Issue:2

    Topics: Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Caudate Nucleus; Cocaine; In Vitro Techniques; Male; Putamen; Receptors, Drug; Saimiri

1990
N-modified fluorophenyltropane analogs of cocaine with high affinity for cocaine receptors.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Discrimination, Psychological; Female; Macaca fascicularis; Male; Nortropanes; Receptors, Drug

1990
Attenuation by dopamine uptake blockers of the inhibitory effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some of its analogs on NADH-linked metabolism in mouse neostriatal slices.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Mice; NAD; Neurotransmitter Uptake Inhibitors; Rats; Tyrosine 3-Monooxygenase

1989
Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.
    Synapse (New York, N.Y.), 1989, Volume: 4, Issue:4

    Topics: Animals; Carrier Proteins; Cocaine; Male; Mice; Receptors, Drug

1989
Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.
    Molecular pharmacology, 1989, Volume: 36, Issue:4

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; In Vitro Techniques; Kinetics; Macaca fascicularis; Putamen; Receptors, Drug

1989
Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Flunarizine; Male; Mice; Nalidixic Acid; Naphthyridines; Piperazines; Pyridines; Pyridinium Compounds; Pyrroles; Rats; Rats, Inbred Strains; Substantia Nigra

1986
Saturable (3H)cocaine binding in central nervous system of mouse.
    Life sciences, 1980, Sep-22, Volume: 27, Issue:12

    Topics: Animals; Brain; Cell Membrane; Cocaine; Male; Mice; Morphine; Naloxone; Neurotransmitter Agents; Nicotine; Tubocurarine

1980
Cocaine cue in pigeons: time course studies and generalization to structurally related compounds (norcocaine, WIN 35,428 and 35,065-2) and (+)-amphetamine.
    British journal of pharmacology, 1981, Volume: 73, Issue:4

    Topics: Animals; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Structure-Activity Relationship; Time Factors

1981
Conditioned taste aversion and operant behavior in rats: effects of cocaine, apomorphine and some long-acting derivatives.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Animals; Apomorphine; Avoidance Learning; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Rats; Taste; Time Factors

1981
Rate of binding of various inhibitors at the dopamine transporter in vivo.
    Psychopharmacology, 1995, Volume: 119, Issue:4

    Topics: Animals; Binding, Competitive; Bupropion; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Time Factors

1995
Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes

1995
Binding of d-threo-[11C]methylphenidate to the dopamine transporter in vivo: insensitivity to synaptic dopamine.
    European journal of pharmacology, 1995, Aug-04, Volume: 281, Issue:2

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Presynaptic Terminals; Rats; Time Factors

1995
Characterization of a recombinant human dopamine transporter in multiple cell lines.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Recombinant Proteins; Tritium; Tumor Cells, Cultured

1995
Effects of cocaine and the cocaine analog CFT on glutamatergic neurons.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:4

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Cocaine; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; Male; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1995
Ion channel inhibitors may function as potential modulators of cocaine binding.
    Neuropharmacology, 1993, Volume: 32, Issue:3

    Topics: Animals; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Cocaine; Corpus Striatum; In Vitro Techniques; Ion Channels; Male; Potassium Channels; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sodium Channels

1993
Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine.
    Brain research, 1994, Dec-30, Volume: 668, Issue:1-2

    Topics: Amygdala; Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Self Stimulation; Serotonin

1994
[3H]WIN 35,428 binding in the caudate nucleus of the rabbit: evidence for a single site on the dopamine transporter.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Animals; Binding Sites; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rabbits

1995
Selective labeling of the dopamine transporter by the high affinity ligand 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester.
    Molecular pharmacology, 1995, Volume: 47, Issue:4

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley

1995
Locomotor stimulant effects of cocaine and novel cocaine analogs in DBA/2J and C57BL/6J inbred mice.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2

    Topics: Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Norepinephrine; Serotonin; Species Specificity; Stereotyped Behavior; Stimulation, Chemical

1995
[3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:3

    Topics: Animals; Carrier Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electrochemistry; Female; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Saimiri; Tritium

1995
Differential relationships among dopamine transporter affinities and stimulant potencies of various uptake inhibitors.
    European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Computer Simulation; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Spermine interacts with cocaine binding sites on dopamine transporters.
    Psychopharmacology, 1994, Volume: 114, Issue:1

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Inbred F344; Receptors, Drug; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spermine

1994
Binding of bromine-substituted analogs of methylphenidate to monoamine transporters.
    European journal of pharmacology, 1994, Oct-24, Volume: 264, Issue:2

    Topics: Animals; Binding, Competitive; Bromine; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Microdialysis; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tomography, Emission-Computed, Single-Photon

1994
Translocation of dopamine and binding of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl) tropane (WIN 35,428) measured under identical conditions in rat striatal synaptosomal preparations. Inhibition by various blockers.
    Biochemical pharmacology, 1995, Jan-31, Volume: 49, Issue:3

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium

1995
Dopamine transporter cysteine mutants: second extracellular loop cysteines are required for transporter expression.
    Journal of neurochemistry, 1995, Volume: 64, Issue:3

    Topics: Animals; Carrier Proteins; Cell Membrane; Chlorocebus aethiops; Cocaine; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Recombinant Proteins; Structure-Activity Relationship

1995
Inhalation anaesthetic competition at high-affinity cocaine binding sites in rat brain synaptosomes.
    British journal of anaesthesia, 1994, Volume: 73, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Binding Sites; Binding, Competitive; Brain; Cocaine; Dose-Response Relationship, Drug; Halothane; Isoflurane; Male; Rats; Rats, Sprague-Dawley; Synaptosomes

1994
Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 11C-CFT.
    Experimental neurology, 1994, Volume: 126, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Dopamine; Motor Activity; Nerve Endings; Parkinson Disease, Secondary; Putamen; Tomography, Emission-Computed

1994
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Guanethidine; Male; Mice; Microdialysis; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neurons; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity; Synaptosomes

1994
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Guanethidine; Male; Mice; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity

1994
Phorbol esters alter functions of the expressed dopamine transporter.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Carrier Proteins; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Kinase C; Rats; Sodium; Tetradecanoylphorbol Acetate

1994
High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Adult; Binding Sites; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Overdose; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins

1994
Can stimulant binding and dopamine transport be differentiated? Studies with GBR 12783 derivatives.
    Life sciences, 1994, Volume: 55, Issue:6

    Topics: Animals; Cocaine; Dopamine; Piperazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen.
    European journal of pharmacology, 1994, Apr-15, Volume: 267, Issue:2

    Topics: Animals; Carrier Proteins; Caudate Nucleus; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Piperidines; Protein Binding; Putamen; Serotonin; Serotonin Plasma Membrane Transport Proteins

1994
Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Models, Molecular; Molecular Conformation; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Characterization of [125I]RTI-55 binding to dog caudate dopamine transporter.
    Neuroreport, 1993, Nov-18, Volume: 5, Issue:2

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cell Membrane; Cholic Acids; Citalopram; Cocaine; Desipramine; Dogs; Dopamine Plasma Membrane Transport Proteins; Filtration; Iodine Radioisotopes; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Solubility

1993
11C-WIN 35,428 for detecting dopamine depletion in mild Parkinson's disease.
    Annals of neurology, 1994, Volume: 35, Issue:3

    Topics: Carbon Radioisotopes; Cocaine; Dopamine; Humans; Parkinson Disease; Tomography, Emission-Computed

1994
Clinical and preclinical PET correlates of parkinsonism with 11C-WIN 35,428.
    Annals of neurology, 1994, Volume: 35, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbon Radioisotopes; Cocaine; Humans; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed

1994
Intravenously administered dopamine transporter site radioligand is not significantly retained in mouse substantia nigra or other sites outside of basal ganglia.
    Annals of neurology, 1994, Volume: 35, Issue:3

    Topics: Animals; Basal Ganglia; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Injections, Intravenous; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Radioligand Assay; Substantia Nigra

1994
Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:5 Pt 2

    Topics: Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Wistar; Reference Values; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tissue Distribution; Tritium

1994
[3H]WIN 35,428 binding to the dopamine uptake carrier. I. Effect of tonicity and buffer composition.
    Journal of neuroscience methods, 1994, Volume: 51, Issue:1

    Topics: Animals; Buffers; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Hypotonic Solutions; Isotonic Solutions; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phosphates; Rats; Rats, Sprague-Dawley; Sodium; Sucrose; Tritium

1994
[3H]WIN 35,428 binding to the dopamine uptake carrier. II. Effect of membrane fractionation procedure and freezing.
    Journal of neuroscience methods, 1994, Volume: 51, Issue:1

    Topics: Animals; Carrier Proteins; Chemical Fractionation; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Freezing; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Tritium

1994
Pharmacogenetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice.
    Pharmacogenetics, 1993, Volume: 3, Issue:4

    Topics: Animals; Benzamides; Benzazepines; Binding Sites; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Limbic System; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nerve Tissue Proteins; Paroxetine; Pharmacogenetics; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Drug; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Sulpiride

1993
Analysis of cocaine receptor site ligand binding by three-dimensional Voronoi site modeling approach.
    Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry, Physical; Cocaine; Corpus Striatum; Models, Molecular; Rats; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

1993
In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428.
    Synapse (New York, N.Y.), 1993, Volume: 15, Issue:2

    Topics: Adult; Affect; Aged; Aged, 80 and over; Animals; Blood Pressure; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Electrocardiography; Female; Humans; Ligands; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Endings; Nerve Tissue Proteins; Papio; Pulse; Receptors, Dopamine; Tomography, Emission-Computed

1993
Cocaine and several sigma receptor ligands inhibit dopamine uptake in rat caudate-putamen.
    European journal of pharmacology, 1993, Oct-19, Volume: 243, Issue:2

    Topics: Affinity Labels; Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, sigma

1993
Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding.
    Molecular pharmacology, 1994, Volume: 45, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cells, Cultured; Cloning, Molecular; Cocaine; DNA; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Piperazines

1994
Cocaine use increases [3H]WIN 35428 binding sites in human striatum.
    Brain research, 1993, Nov-19, Volume: 628, Issue:1-2

    Topics: Adult; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Tritium

1993
[3H]CFT ([3H]WIN 35,428) accumulation in dopamine regions of monkey brain: comparison of a mature and an aged monkey.
    Brain research, 1993, May-21, Volume: 611, Issue:2

    Topics: Aging; Animals; Brain; Cocaine; Corpus Striatum; Injections, Intravenous; Saimiri; Time Factors; Tissue Distribution; Tritium

1993
Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease.
    Annals of neurology, 1993, Volume: 34, Issue:3

    Topics: Biomarkers; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Nerve Tissue Proteins; Organ Specificity; Parkinson Disease; Putamen; Tomography, Emission-Computed

1993
Studies of the biogenic amine transporters. II. A brief study on the use of [3H]DA-uptake-inhibition to transporter-binding-inhibition ratios for the in vitro evaluation of putative cocaine antagonists.
    Life sciences, 1993, Volume: 53, Issue:17

    Topics: Animals; Biogenic Amines; Biological Transport; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Tritium

1993
Comparison of [3H]WIN 35,428 binding, a marker for dopamine transporter, in embryonic mesencephalic neuronal cultures with striatal membranes of adult rats.
    Journal of neurochemistry, 1993, Volume: 60, Issue:2

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cell Membrane; Cells, Cultured; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Embryo, Mammalian; Female; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Tritium

1993
Zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex.
    Molecular pharmacology, 1993, Volume: 43, Issue:1

    Topics: Animals; Binding, Competitive; Buffers; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ethylmaleimide; In Vitro Techniques; Male; Membrane Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Zinc

1993
The cocaine analog WIN 35,428 binds to two sites in fresh rat caudate-putamen: significance of assay procedures.
    Life sciences, 1993, Volume: 52, Issue:16

    Topics: Animals; Binding Sites; Caudate Nucleus; Cocaine; In Vitro Techniques; Male; Putamen; Radioligand Assay; Rats; Rats, Sprague-Dawley

1993
Cationic and anionic requirements for the binding of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)[3H]tropane to the dopamine uptake carrier.
    Journal of neurochemistry, 1993, Volume: 61, Issue:1

    Topics: Animals; Anions; Carrier Proteins; Cations; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phosphates; Potassium; Rats; Sodium; Tritium

1993
Multiple drug classes and hyperosmolarity alter binding of muscarinic drugs to mesothelial cells in vitro.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1995, Volume: 11

    Topics: Animals; Atropine; Cells, Cultured; Cocaine; Cycloheximide; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Epithelium; Mannitol; Muscarinic Antagonists; N-Methylscopolamine; Osmolar Concentration; Parasympatholytics; Peritoneum; Piperazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Sodium Chloride

1995
Localization and quantification of the dopamine transporter: comparison of [3H]WIN 35,428 and [125I]RTI-55.
    Brain research, 1995, Sep-04, Volume: 690, Issue:2

    Topics: Animals; Autoradiography; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tritium

1995
Behavioral sensitization, behavioral tolerance, and increased [3H]WIN 35,428 binding in rabbit caudate nucleus after repeated injections of cocaine.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2

    Topics: Animals; Behavior, Animal; Binding Sites; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Tolerance; Female; Injections, Intravenous; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Motor Activity; Narcotics; Nerve Tissue Proteins; Rabbits; Seizures; Up-Regulation

1995
Conformational analysis of methylphenidate and its structural relationship to other dopamine reuptake blockers such as CFT.
    Pharmaceutical research, 1995, Volume: 12, Issue:10

    Topics: Cocaine; Crystallography, X-Ray; Dopamine Uptake Inhibitors; Methylphenidate; Molecular Structure; Stereoisomerism

1995
PET examination of the monoamine transporter with [11C]beta-CIT and [11C]beta-CFT in early Parkinson's disease.
    Synapse (New York, N.Y.), 1995, Volume: 21, Issue:2

    Topics: Adult; Biological Transport; Brain; Carbon Radioisotopes; Cocaine; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neuropeptides; Parkinson Disease; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins

1995
Effects of WIN 35,428 a potent antagonist of dopamine transporter on sleep and locomotor activity in rats.
    Neuroreport, 1995, Nov-13, Volume: 6, Issue:16

    Topics: Analysis of Variance; Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Rats; Rats, Wistar; Sleep

1995
[3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions.
    Biochemical pharmacology, 1996, Feb-23, Volume: 51, Issue:4

    Topics: Animals; Brain; Cell Membrane; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Mesencephalon; Nerve Endings; Nucleus Accumbens; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tritium

1996
The vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, May-15, Volume: 16, Issue:10

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Self Administration; Tetrabenazine

1996
Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs.
    Journal of medicinal chemistry, 1996, Mar-15, Volume: 39, Issue:6

    Topics: Animals; Cocaine; Dopamine; Male; Methylphenidate; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1996
Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Adolescent; Adult; Brain; Carbon Radioisotopes; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kinetics; Lesch-Nyhan Syndrome; Magnetic Resonance Imaging; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Organ Specificity; Putamen; Reference Values; Rett Syndrome; Time Factors; Tomography, Emission-Computed

1996
Synthesis and ligand binding of eta(6)-(2beta-carbomethoxy-3beta-phenyltropane) transition metal complexes.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Organometallic Compounds; Putamen; Rats; Structure-Activity Relationship; Tropanes

1996
The dopamine transporter carboxyl-terminal tail. Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain.
    The Journal of biological chemistry, 1996, Aug-23, Volume: 271, Issue:34

    Topics: Animals; Base Sequence; Binding Sites; Biological Transport; Carrier Proteins; Cells, Cultured; Chlorocebus aethiops; Cocaine; DNA Primers; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Recombinant Fusion Proteins; Sequence Deletion; Structure-Activity Relationship

1996
Effect of dopaminergic drugs on the in vivo binding of [3H]WIN 35,428 to central dopamine transporters.
    Synapse (New York, N.Y.), 1996, Volume: 23, Issue:2

    Topics: Amphetamine; Animals; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins

1996
Modeling of the pH dependence of the binding of WIN 35,428 to the dopamine transporter in rat striatal membranes: is the bioactive form positively charged or neutral?
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Animals; Benzocaine; Binding, Competitive; Carrier Proteins; Cations; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Synaptosomes

1996
[3H]WIN 35,428 binding in the human brain.
    Brain research, 1996, Jan-15, Volume: 706, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Brain; Cocaine; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Humans; Male; Middle Aged; Paroxetine; Radioligand Assay; Selective Serotonin Reuptake Inhibitors

1996
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine; Nortropanes; Paroxetine; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes

1996
The cocaine-like behavioral effects of meperidine are mediated by activity at the dopamine transporter.
    European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2

    Topics: Animals; Behavior, Animal; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Meperidine; Models, Molecular; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Saimiri

1996
[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: biodistribution in rats.
    Synapse (New York, N.Y.), 1996, Volume: 23, Issue:4

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluorine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed

1996
Recovery of dopamine transporter binding and function after intrastriatal administration of the irreversible inhibitor RTI-76 [3 beta-(3p-chlorophenyl) tropan-2 beta-carboxylic acid p-isothiocyanatophenylethyl ester hydrochloride].
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Tropanes

1996
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
    Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21

    Topics: Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Serotonin; Stereoisomerism; Structure-Activity Relationship

1996
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI-121.
    Synapse (New York, N.Y.), 1995, Volume: 21, Issue:4

    Topics: Adult; Autoradiography; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Tissue Distribution

1995
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
    European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley

1996
The effects of phosphorylation on the functional regulation of an expressed recombinant human dopamine transporter.
    Neuroscience letters, 1996, Sep-27, Volume: 216, Issue:2

    Topics: Animals; Blotting, Western; Carrier Proteins; Cocaine; COS Cells; DNA, Complementary; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glycosylation; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phosphorus Radioisotopes; Phosphorylation; Recombinant Proteins; Transfection; Tritium

1996
Quantification of dopamine transporter density in monkeys by dynamic PET imaging of multiple injections of 11C-CFT.
    Synapse (New York, N.Y.), 1996, Volume: 24, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cerebellum; Cocaine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Image Processing, Computer-Assisted; Isotope Labeling; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Neurological; Motor Skills; MPTP Poisoning; Neostriatum; Nerve Tissue Proteins; Receptors, Dopamine; Tomography, Emission-Computed

1996
Enhanced amphetamine sensitivity and increased expression of dopamine D2 receptors in postpubertal rats after neonatal excitotoxic lesions of the medial prefrontal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Nov-15, Volume: 16, Issue:22

    Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Benzamides; Benzazepines; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; In Situ Hybridization; Locomotion; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotoxins; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sensitivity and Specificity; Sexual Maturation; Tetrahydronaphthalenes; Tritium

1996
Binding domains for blockers and substrates on the cloned human dopamine transporter studied by protection against N-ethylmaleimide-induced reduction of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)[3H]tropane ([3H]WIN 35,428) binding.
    Biochemical pharmacology, 1996, Nov-08, Volume: 52, Issue:9

    Topics: Animals; Binding Sites; Carrier Proteins; Cell Membrane; Cloning, Molecular; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ethylmaleimide; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Transfection; Tumor Cells, Cultured

1996
The stimulatory and inhibitory components of cocaine's actions on the 5-HTP-induced 5-HT2A receptor response.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:3

    Topics: 1-Naphthylamine; 5-Hydroxytryptophan; Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline

1996
Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
    Journal of medicinal chemistry, 1996, Dec-06, Volume: 39, Issue:25

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats

1996
In vivo regulation of central nervous system progesterone receptors: cocaine induces steroid-dependent behavior through dopamine transporter modulation of D5 receptors in rats.
    Molecular endocrinology (Baltimore, Md.), 1996, Volume: 10, Issue:12

    Topics: Animals; Antisense Elements (Genetics); Behavior, Animal; Carrier Proteins; Central Nervous System; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Membrane Glycoproteins; Membrane Transport Proteins; Mifepristone; Narcotics; Nerve Tissue Proteins; Neurons; Ovariectomy; Posture; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D5; Receptors, Progesterone; Sexual Behavior, Animal; Steroids; Ventromedial Hypothalamic Nucleus

1996
Cocaine congeners as PET imaging probes for dopamine terminals.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Macaca fascicularis; Male; Nerve Endings; Parkinson Disease, Secondary; Tomography, Emission-Computed

1996
Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:7

    Topics: Animals; Autoradiography; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Saimiri; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon

1996
Regulation of the functional activity of the human dopamine transporter by the arachidonic acid pathway.
    European journal of pharmacology, 1996, Nov-21, Volume: 315, Issue:3

    Topics: Animals; Arachidonic Acid; Brain Neoplasms; Carrier Proteins; Cattle; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Glioma; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins

1996
Effects of drugs on food- and cocaine-maintained responding, III: Dopaminergic antagonists.
    Psychopharmacology, 1996, Volume: 128, Issue:4

    Topics: Animals; Benzazepines; Chlorpromazine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Food; Macaca mulatta; Male; Narcotics; Pimozide; Self Administration

1996
Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]beta-CIT and [11C]beta-CFT.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:8

    Topics: Carbon Isotopes; Cocaine; Dopamine Uptake Inhibitors; Hydrocarbons, Iodinated; Indicators and Reagents; Isotope Labeling; Mesylates; Methylation; Radioactive Tracers; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1995
Binding domains for blockers and substrates on the dopamine transporter in rat striatal membranes studied by protection against N-ethylmaleimide-induced reduction of [3H]WIN 35,428 binding.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:1

    Topics: Amphetamine; Animals; Binding Sites; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ethylmaleimide; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Conformation; Rats; Rats, Sprague-Dawley; Sodium; Tritium

1997
Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
    Journal of medicinal chemistry, 1997, Jan-03, Volume: 40, Issue:1

    Topics: Animals; Carrier Proteins; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats

1997
Comparative evaluation of [3H]WIN 35428 and [3H]GBR 12935 as markers of dopamine innervation density in brain.
    Synapse (New York, N.Y.), 1997, Volume: 25, Issue:2

    Topics: Animals; Autoradiography; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Piperazines; Rats; Rats, Sprague-Dawley

1997
3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Animals; Benztropine; Binding, Competitive; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Neostriatum; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tropanes

1997
Synthesis, dopamine transporter affinity, dopamine uptake inhibition, and locomotor stimulant activity of 2-substituted 3 beta-phenyltropane derivatives.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Nerve Tissue Proteins; Rats; Tropanes

1997
Striatal dopamine nerve terminal markers but not nigral cellularity are reduced in spinocerebellar ataxia type 1.
    Neurology, 1997, Volume: 48, Issue:4

    Topics: Adult; Biomarkers; Cadaver; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Endings; Nerve Tissue Proteins; Putamen; Spinocerebellar Degenerations; Substantia Nigra; Tetrabenazine

1997
Regulation of the functional activity of the human dopamine transporter by protein kinase C.
    Biochemical pharmacology, 1997, Mar-07, Volume: 53, Issue:5

    Topics: Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
Synthesis and ligand binding studies of 4'-iodobenzoyl esters of tropanes and piperidines at the dopamine transporter.
    Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16

    Topics: Animals; Binding Sites; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Esters; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Models, Molecular; Nerve Tissue Proteins; Piperidines; Rats; Rats, Sprague-Dawley; Tropanes

1997
WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: Binding, Competitive; Carrier Proteins; Cloning, Molecular; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Nerve Tissue Proteins; Radioligand Assay; Recombinant Proteins; Tritium; Tumor Cells, Cultured

1997
Cations affect [3H]mazindol and [3H]WIN 35,428 binding to the human dopamine transporter in a similar fashion.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Animals; Carrier Proteins; Cations, Divalent; Cations, Monovalent; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glioma; Humans; Kinetics; Lithium; Magnesium; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mercury; Nerve Tissue Proteins; Potassium; Protein Binding; Rats; Sodium; Tritium; Tumor Cells, Cultured; Zinc

1997
Positron emission tomography radioligands for dopamine transporters and studies in human and nonhuman primates.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Parkinson Disease; Primates; Radioligand Assay; Radiopharmaceuticals; Reference Values; Substance-Related Disorders; Tomography, Emission-Computed

1998
Dopamine transporter changes in neuropsychiatric disorders.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Child; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Iodine Radioisotopes; Lesch-Nyhan Syndrome; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Reference Values; Rett Syndrome; Substance-Related Disorders; Tomography, Emission-Computed; Tourette Syndrome

1998
Use of identical assay conditions for cocaine analog binding and dopamine uptake to identify potential cocaine antagonists.
    Drug and alcohol dependence, 1997, Oct-25, Volume: 48, Issue:1

    Topics: Animals; Binding, Competitive; Carrier Proteins; CHO Cells; Cocaine; Cricetinae; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Structure-Activity Relationship

1997
In vivo saturation kinetics of two dopamine transporter probes measured using a small animal positron emission tomography scanner.
    Journal of neuroscience methods, 1997, Sep-05, Volume: 76, Issue:1

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Tomography, Emission-Computed

1997
Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data.
    Magnetic resonance in medicine, 1997, Volume: 38, Issue:3

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain; Cocaine; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Magnetic Resonance Imaging; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Sensitivity and Specificity; Tomography, Emission-Computed

1997
Chronic administration of the selective dopamine uptake inhibitor GBR 12,909, but not cocaine, produces marked decreases in dopamine transporter density.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:5

    Topics: Animals; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Piperazines; Rats; Rats, Sprague-Dawley

1997
Brain dopamine neurotoxicity in baboons treated with doses of methamphetamine comparable to those recreationally abused by humans: evidence from [11C]WIN-35,428 positron emission tomography studies and direct in vitro determinations.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jan-01, Volume: 18, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Neostriatum; Nerve Tissue Proteins; Neurotoxins; Papio; Substance-Related Disorders; Tomography, Emission-Computed; Tritium

1998
Parametric imaging of ligand-receptor binding in PET using a simplified reference region model.
    NeuroImage, 1997, Volume: 6, Issue:4

    Topics: Animals; Benzazepines; Brain; Brain Mapping; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Image Processing, Computer-Assisted; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Tomography, Emission-Computed

1997
2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding.
    Neuroreport, 1997, Nov-10, Volume: 8, Issue:16

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Symporters

1997
gamma-Aminobutyric acidA agonists differentially augment gnawing induced by indirect-acting dopamine agonists in C57BL/6J mice.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1

    Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Agonists; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Piperazines

1998
Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Models, Molecular; Molecular Structure; Motor Activity; Nerve Tissue Proteins; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes

1997
Isothiocyanate derivatives of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole): irreversible ligands for the dopamine transporter.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carbazoles; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guinea Pigs; Isothiocyanates; Ligands; Liver; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Receptors, sigma

1997
Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Rats; Tropanes

1997
Striatal uptake of the dopamine reuptake ligand [11C]beta-CFT is reduced in Alzheimer's disease assessed by positron emission tomography.
    Neurology, 1998, Volume: 50, Issue:1

    Topics: Age Factors; Aged; Alzheimer Disease; Carbon Radioisotopes; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Ligands; Male; Middle Aged; Tomography, Emission-Computed

1998
Measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Iodine Radioisotopes; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Papio; Radioligand Assay; Tomography, Emission-Computed

1998
Synthesis and ligand binding of tropane ring analogues of paroxetine.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Binding, Competitive; Cocaine; Dopamine Uptake Inhibitors; Isomerism; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Paroxetine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tropanes

1998
Dopamine transporter development in postnatal rat striatum: an autoradiographic study with [3H]WIN 35,428.
    Brain research. Developmental brain research, 1997, Dec-19, Volume: 104, Issue:1-2

    Topics: Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tritium

1997
Pharmacological constraints associated with positron emission tomographic scanning of small laboratory animals.
    European journal of nuclear medicine, 1998, Volume: 25, Issue:2

    Topics: Animals; Body Weight; Brain; Carbon Radioisotopes; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Ligands; Mice; Piperazines; Pyridines; Raclopride; Radioactivity; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Salicylamides; Serotonin Antagonists; Tomography, Emission-Computed

1998
[18F]CFT [(18F)WIN 35,428], a radioligand to study the dopamine transporter with PET: characterization in human subjects.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:3

    Topics: Adult; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Presynaptic Terminals; Sensitivity and Specificity; Tomography, Emission-Computed

1998
Unchanged density of caudate nucleus dopamine uptake sites in depressed suicide victims.
    Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:11-12

    Topics: Adult; Aged; Aged, 80 and over; Caudate Nucleus; Cocaine; Depressive Disorder; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Ligands; Male; Middle Aged; Receptors, Dopamine; Suicide

1997
Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain.
    Synapse (New York, N.Y.), 1998, Volume: 29, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Iodine Radioisotopes; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1998
Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperidines; Protein Binding; Rats; Stereoisomerism; Synaptosomes; Tropanes

1998
Synthesis and dopamine transporter affinity of the four stereoisomers of (+/-)-2-(methoxycarbonyl)-7-methyl-3-phenyl-7-azabicyclo[2.2.1]heptane.
    Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Molecular Conformation; Nerve Tissue Proteins; Protein Binding; Putamen; Rats; Stereoisomerism; Tropanes

1998
Delineation of an endogenous zinc-binding site in the human dopamine transporter.
    The EMBO journal, 1998, Aug-03, Volume: 17, Issue:15

    Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cocaine; Conserved Sequence; COS Cells; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Histidine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Zinc

1998
Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Aug-04, Volume: 95, Issue:16

    Topics: Carrier Proteins; Cell Line; Cocaine; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Tritium

1998
Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17

    Topics: Animals; Carrier Proteins; Cell Line; Citalopram; Cloning, Molecular; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Transfection

1998
Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter.
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:1

    Topics: Animals; Carrier Proteins; Cell Line; Cloning, Molecular; Cocaine; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phorbol Esters; Protein Kinase C; Recombinant Proteins; Spodoptera; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection

1998
Expression and regulation of the human dopamine transporter in a neuronal cell line.
    Brain research. Molecular brain research, 1998, Aug-15, Volume: 59, Issue:1

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Enzyme Activation; Gene Expression Regulation, Developmental; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neurons; Paroxetine; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1998
Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Oct-15, Volume: 18, Issue:20

    Topics: Adult; Amphetamine-Related Disorders; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Middle Aged; Neostriatum; Nerve Tissue Proteins; Parkinson Disease, Secondary; Propiophenones; Tomography, Emission-Computed

1998
Specificity and ion dependence of binding of GBR analogs.
    Methods in enzymology, 1998, Volume: 296

    Topics: Animals; Carrier Proteins; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tritium

1998
Inhibition of [3H]dopamine translocation and [3H]cocaine analog binding: a potential screening device for cocaine antagonists.
    Methods in enzymology, 1998, Volume: 296

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Fractionation; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Design; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radioligand Assay; Rats; Sodium; Software; Tritium

1998
Novel rhenium complexes derived from alpha-tropanol as potential ligands for the dopamine transporter.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:10

    Topics: Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Crystallography, X-Ray; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rhenium; Structure-Activity Relationship; Tropanes

1998
Novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1

    Topics: Animals; Cocaine; Discrimination Learning; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Pirenzepine; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Tropanes

1999
Nature of methamphetamine-induced rapid and reversible changes in dopamine transporters.
    European journal of pharmacology, 1998, Nov-20, Volume: 361, Issue:2-3

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1998
Dizocilpine and reduced body temperature do not prevent methamphetamine-induced neurotoxicity in the vervet monkey: [11C]WIN 35,428 - positron emission tomography studies.
    Neuroscience letters, 1998, Dec-11, Volume: 258, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Chlorocebus aethiops; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hypothermia; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Neuroprotective Agents; Tomography, Emission-Computed

1998
Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum.
    Journal of neurochemistry, 1999, Volume: 72, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoreceptors; Brain Chemistry; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Extracellular Space; Female; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Salicylamides; Tritium

1999
PET imaging of the pre-synaptic dopamine uptake sites in rapid-onset dystonia-parkinsonism (RDP).
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:1

    Topics: Adult; Aged; Brain Mapping; Carbon Radioisotopes; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Uptake Inhibitors; Dystonia; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pilot Projects; Receptors, Dopamine; Receptors, Presynaptic; Tomography, Emission-Computed

1999
Which form of dopamine is the substrate for the human dopamine transporter: the cationic or the uncharged species?
    The Journal of biological chemistry, 1999, Feb-19, Volume: 274, Issue:8

    Topics: Binding Sites; Bretylium Compounds; Carrier Proteins; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Guanethidine; Humans; Hydrogen-Ion Concentration; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons

1999
Striatal dopaminergic abnormalities in human cocaine users.
    The American journal of psychiatry, 1999, Volume: 156, Issue:2

    Topics: Adolescent; Adult; Autoradiography; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Receptors, Dopamine; Severity of Illness Index; Tritium

1999
Striatal uptake of a novel PET ligand, [18F]beta-CFT, is reduced in early Parkinson's disease.
    Synapse (New York, N.Y.), 1999, Volume: 31, Issue:2

    Topics: Aged; Animals; Caudate Nucleus; Cocaine; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed

1999
Age-related reductions in [3H]WIN 35,428 binding to the dopamine transporter in nigrostriatal and mesolimbic brain regions of the fischer 344 rat.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Age Factors; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred F344; Substantia Nigra; Tritium; Ventral Tegmental Area

1999
Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter.
    Journal of neurochemistry, 1999, Volume: 72, Issue:3

    Topics: Algorithms; Binding, Competitive; Carrier Proteins; Cell Line; Chlorides; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Models, Neurological; Nerve Tissue Proteins; Potassium; Protein Binding; Sodium

1999
Effects of methylphenidate analogues on phenethylamine substrates for the striatal dopamine transporter: potential as amphetamine antagonists?
    Journal of neurochemistry, 1999, Volume: 72, Issue:3

    Topics: Algorithms; Amphetamine; Animals; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrodes; In Vitro Techniques; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Neostriatum; Nerve Tissue Proteins; Phenethylamines; Rats; Rats, Sprague-Dawley

1999
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors.
    Journal of medicinal chemistry, 1999, Mar-11, Volume: 42, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds; Cocaine; Cocaine-Related Disorders; Discrimination Learning; Dopamine; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Models, Molecular; Neostriatum; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Synaptosomes

1999
Nongenomic steroidal modulation of high-affinity serotonin transport.
    Biochimica et biophysica acta, 1999, Feb-04, Volume: 1417, Issue:1

    Topics: Animals; Carrier Proteins; Cell Line; Cocaine; Dose-Response Relationship, Drug; Estradiol; Humans; Ion Channels; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Receptors, Neurotransmitter; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tamoxifen; Time Factors

1999
Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans.
    Synapse (New York, N.Y.), 1999, Volume: 32, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Cocaine; Depression, Chemical; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Infusions, Intravenous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Piperazines; Self Administration; Tomography, Emission-Computed

1999
Pharmacological profile of neuroleptics at human monoamine transporters.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium

1999
Simultaneous SPECT studies of pre- and postsynaptic dopamine binding sites in baboons.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:4

    Topics: Animals; Benzamides; Benzofurans; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organotechnetium Compounds; Papio; Pyrrolidines; Raclopride; Radiopharmaceuticals; Receptors, Dopamine; Salicylamides; Tomography, Emission-Computed, Single-Photon; Tropanes

1999
PET imaging of the dopamine transporter in progressive supranuclear palsy and Parkinson's disease.
    Neurology, 1999, Apr-12, Volume: 52, Issue:6

    Topics: Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Supranuclear Palsy, Progressive; Tomography, Emission-Computed

1999
Alterations in binding site density of dopamine transporter in the striatum, orbitofrontal cortex, and amygdala in early Parkinson's disease: compartment analysis for beta-CFT binding with positron emission tomography.
    Annals of neurology, 1999, Volume: 45, Issue:5

    Topics: Aged; Amygdala; Binding Sites; Brain; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Frontal Lobe; Humans; Kinetics; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Orbit; Parkinson Disease; Radiography; Time Factors; Tomography, Emission-Computed

1999
Regional and temporal expression of the peripheral benzodiazepine receptor in MPTP neurotoxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 48, Issue:1

    Topics: Animals; Autoradiography; Biomarkers; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Isoquinolines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Endings; Nerve Tissue Proteins; Neurons; Receptors, GABA-A; Sensitivity and Specificity; Substantia Nigra; Tritium; Tyrosine 3-Monooxygenase

1999
Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1999, Volume: 53, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Animals; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Haplorhini; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Models, Biological; Parkinson Disease; Tomography, Emission-Computed; Visual Cortex

1999
Although chemically related to amineptine, the antidepressant tianeptine is not a dopamine uptake inhibitor.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Benzazepines; Cocaine; Corpus Striatum; Dextroamphetamine; Dibenzocycloheptenes; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; In Vitro Techniques; Male; Mice; Motor Activity; Radioligand Assay; Thiazepines

1999
Tyrosine hydroxylase immunoreactivity and [3H]WIN 35,428 binding to the dopamine transporter in a hamster model of idiopathic paroxysmal dystonia.
    Neuroscience, 1999, Volume: 92, Issue:1

    Topics: Animals; Carrier Proteins; Cocaine; Cricetinae; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dystonia; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Tegmentum Mesencephali; Tritium; Tyrosine 3-Monooxygenase

1999
Apparent dopamine D1 and D2 receptors in the weaver mutant mouse: receptor binding and coupling to adenylyl cyclase.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:5-6

    Topics: Adenylyl Cyclases; Animals; Autoradiography; Benzamides; Benzazepines; Cocaine; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Antagonists; Down-Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Limbic System; Mice; Mice, Neurologic Mutants; Nerve Degeneration; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Signal Transduction; Substantia Nigra; Tritium

1999
Studies of selected phenyltropanes at monoamine transporters.
    Drug and alcohol dependence, 1999, Aug-02, Volume: 56, Issue:1

    Topics: Adult; Aged; Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Putamen; Rats; Rats, Sprague-Dawley; Rhombencephalon; Serotonin Plasma Membrane Transport Proteins; Symporters; Tropanes

1999
CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Animals; Binding Sites; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Tropanes

1999
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
    Synapse (New York, N.Y.), 1999, Volume: 34, Issue:2

    Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Interactions; Fluorine Radioisotopes; Humans; Nicotine; Raclopride; Radiopharmaceuticals; Selegiline; Tomography, Emission-Computed

1999
Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment.
    Neuroreport, 1999, Sep-29, Volume: 10, Issue:14

    Topics: Amphetamine; Animals; Behavior, Animal; Cell Transplantation; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Magnetic Resonance Imaging; Microdialysis; Neurons; Rats; Rats, Sprague-Dawley; Striatonigral Degeneration; Sympathectomy, Chemical; Tomography, Emission-Computed

1999
Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study.
    Annals of neurology, 1999, Volume: 46, Issue:5

    Topics: Aged; Benzazepines; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Functional Laterality; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D1; Reference Values; Substantia Nigra; Tomography, Emission-Computed

1999
Alterations in serotonin receptors in the neostriatum of weaver mutant mice.
    Neurochemical research, 1999, Volume: 24, Issue:11

    Topics: Amphetamines; Animals; Citalopram; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Neurologic Mutants; Mutation; Neostriatum; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Tritium

1999
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
    Journal of medicinal chemistry, 1999, Nov-18, Volume: 42, Issue:23

    Topics: Animals; Benzoates; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters

1999
Isoflurane anesthesia enhances the inhibitory effects of cocaine and GBR12909 on dopamine transporter: PET studies in combination with microdialysis in the monkey brain.
    Brain research, 1999, Dec-04, Volume: 849, Issue:1-2

    Topics: Anesthesia, Inhalation; Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Isoflurane; Kinetics; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Piperazines; Receptors, Dopamine D2; Time Factors; Tomography, Emission-Computed; Wakefulness

1999
Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.
    The Journal of biological chemistry, 1999, Dec-24, Volume: 274, Issue:52

    Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Tertiary; Structure-Activity Relationship; Zinc

1999
Nitrogen-based drugs are not essential for blockade of monoamine transporters.
    Synapse (New York, N.Y.), 1996, Volume: 24, Issue:4

    Topics: Animals; Binding Sites; Carrier Proteins; Citalopram; Cocaine; COS Cells; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nitrogen; Norepinephrine; Putamen; Radioligand Assay

1996
Long-term methamphetamine-induced decreases of [(11)C]WIN 35,428 binding in striatum are reduced by GDNF: PET studies in the vervet monkey.
    Synapse (New York, N.Y.), 2000, Mar-15, Volume: 35, Issue:4

    Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Chlorocebus aethiops; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glial Cell Line-Derived Neurotrophic Factor; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Growth Factors; Nerve Tissue Proteins; Neurotoxins; Putamen; Tomography, Emission-Computed

2000
Loss of dopamine uptake sites and dopamine D2 receptors in striatonigral degeneration.
    Brain research, 2000, Jan-03, Volume: 852, Issue:1

    Topics: Aged; Autoradiography; Benzamides; Cadaver; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D2; Reference Values; Striatonigral Degeneration

2000
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects.
    Psychopharmacology, 2000, Volume: 148, Issue:1

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Psychomotor Performance; Putamen; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Tritium; Zimeldine

2000
Striatal dopamine transporter binding in neuroleptic-naive patients with schizophrenia studied with positron emission tomography.
    The American journal of psychiatry, 2000, Volume: 157, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Functional Laterality; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Schizophrenia; Tomography, Emission-Computed

2000
Prediction of detached personality in healthy subjects by low dopamine transporter binding.
    The American journal of psychiatry, 2000, Volume: 157, Issue:2

    Topics: Adult; Age Factors; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Functional Laterality; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Multivariate Analysis; Nerve Tissue Proteins; Personality; Personality Inventory; Putamen; Tomography, Emission-Computed

2000
Efficient HPLC separation of [11C]beta-CFT or [11C]beta-CIT from an N-desmethyl precursor on a semipreparative reversed phase ODS column.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2000, Volume: 52, Issue:2

    Topics: Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine

2000
Detection of the effects of dopamine receptor supersensitivity using pharmacological MRI and correlations with PET.
    Synapse (New York, N.Y.), 2000, Volume: 36, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Cerebrovascular Circulation; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Hemodynamics; Magnetic Resonance Imaging; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Tomography, Emission-Computed

2000
2Beta-carbomethoxy-3beta-(4- and 2-[18F]fluoromethylphenyl)tropanes: specific probes for in vivo quantification of central dopamine transporter sites.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:8

    Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Chlorocebus aethiops; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Image Processing, Computer-Assisted; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Serotonin; Tomography, Emission-Computed; Tropanes

1999
Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76.
    Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Injections, Intraventricular; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Symporters; Tropanes

2000
3-Aryl-2-carbomethoxybicyclo[3.2.1]oct-2-enes inhibit WIN 35,428 binding potently and selectively at the dopamine transporter.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:3

    Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tritium

2000
Interaction of Na+, K+, and Cl- with the binding of amphetamine, octopamine, and tyramine to the human dopamine transporter.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Allosteric Regulation; Amphetamine; Binding Sites; Biological Transport; Carrier Proteins; Cell Line; Chlorides; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Nerve Tissue Proteins; Octopamine; Potassium; Sodium; Tritium; Tyramine

2000
Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Animals; Biological Transport, Active; Carrier Proteins; Cell Membrane; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gene Expression; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Proline; Protein Conformation; Transfection

2000
In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cocaine; Dopamine Agents; Dopamine Uptake Inhibitors; Indicators and Reagents; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Microscopy, Electron; Neostriatum; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Species Specificity; Synaptic Vesicles; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2000
Toward development of an in vitro model of methamphetamine-induced dopamine nerve terminal toxicity.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Animals; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fenfluramine; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Methamphetamine; Neostriatum; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Synaptosomes; Temperature; Time Factors

2000
Importance of valine at position 152 for the substrate transport and 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane binding of dopamine transporter.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport; Carrier Proteins; Cattle; Cocaine; COS Cells; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Isoleucine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Valine

2000
Dopamine transporter transmembrane domain polar mutants: DeltaG and DeltaDeltaG values implicate regions important for transporter functions.
    Molecular pharmacology, 2000, Volume: 57, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Protein Conformation; Rats; Transfection; Tritium

2000
Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand [18F]CFT.
    Annals of neurology, 2000, Volume: 47, Issue:6

    Topics: Aged; Antiparkinson Agents; Brain; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Time Factors; Tomography, Emission-Computed

2000
Effects of oligonucleotide antisense to dopamine D(1A) receptor messenger RNA in a rodent model of levodopa-induced dyskinesia.
    Neuroscience, 2000, Volume: 98, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Cocaine; Denervation; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Gene Expression; Levodopa; Male; Oligonucleotides, Antisense; Oxidopamine; Phenotype; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Rotation; Substantia Nigra; Sympatholytics; Tritium

2000
Ketamine decreased striatal [(11)C]raclopride binding with no alterations in static dopamine concentrations in the striatal extracellular fluid in the monkey brain: multiparametric PET studies combined with microdialysis analysis.
    Synapse (New York, N.Y.), 2000, Volume: 37, Issue:2

    Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Ketamine; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Osmolar Concentration; Raclopride; Tomography, Emission-Computed

2000
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity.
    Synapse (New York, N.Y.), 2000, Sep-01, Volume: 37, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Apomorphine; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Cytoprotection; Dopamine Plasma Membrane Transport Proteins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Tissue Proteins; Oligonucleotides, Antisense; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tritium

2000
Reinstatement of extinguished drug-taking behavior in rats: effect of the kappa-opioid receptor agonist, U69593.
    Psychopharmacology, 2000, Volume: 151, Issue:1

    Topics: Analgesics; Animals; Benzeneacetamides; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa

2000
Effect of cocaine, nomifensine, GBR 12909 and WIN 35428 on carbon fiber microelectrode sensitivity for voltammetric recording of dopamine.
    Journal of neuroscience methods, 2000, Aug-15, Volume: 101, Issue:1

    Topics: Animals; Artifacts; Calibration; Carbon; Coated Materials, Biocompatible; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Electrodes, Implanted; Equipment Failure; Fluorocarbon Polymers; Male; Microelectrodes; Nomifensine; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

2000
Cholinergic neuronal modulation alters dopamine D2 receptor availability in vivo by regulating receptor affinity induced by facilitated synaptic dopamine turnover: positron emission tomography studies with microdialysis in the conscious monkey brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-15, Volume: 20, Issue:18

    Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cholinergic Fibers; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Piperazines; Raclopride; Receptors, Dopamine D2; Scopolamine; Synapses; Tomography, Emission-Computed; Wakefulness

2000
Binding of uptake blockers to the neuronal dopamine transporter: further investigation about cationic and anionic requirements.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:3

    Topics: Animals; Anions; Binding Sites; Cations; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Mazindol; Rats; Rats, Sprague-Dawley

2000
RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:3

    Topics: Binding Sites; Carrier Proteins; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Tropanes

2000
Column-switching HPLC for the analysis of plasma in PET imaging studies.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cocaine; Dopamine Agents; Imidazoles; Isoquinolines; Ligands; Pyridines; Raclopride; Sensitivity and Specificity; Solvents; Tetrabenazine; Time Factors; Tomography, Emission-Computed; Urea

2000
Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease.
    Experimental neurology, 2000, Volume: 166, Issue:2

    Topics: Animals; Autoradiography; Benzazepines; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Energy Metabolism; Female; Fluorodeoxyglucose F18; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; In Situ Hybridization; Nerve Degeneration; Neurotoxins; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Substantia Nigra; Tomography, Emission-Computed; Tritium

2000
Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carrier Proteins; Cations; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Conformation; Radioligand Assay; Signal Transduction; Tritium; Tryptophan

2000
Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent.
    Molecular pharmacology, 2001, Volume: 59, Issue:1

    Topics: Animals; Biological Transport; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrophysiology; Gene Expression Regulation; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Radioligand Assay; Receptors, Dopamine D2; Transfection; Xenopus laevis

2001
Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Feb-15, Volume: 21, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biological Transport; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Methamphetamine; Methylphenidate; Models, Biological; Nerve Tissue Proteins; Norepinephrine; Onium Compounds; Organophosphorus Compounds; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes

2001
Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.
    Synapse (New York, N.Y.), 2001, Volume: 39, Issue:2

    Topics: Animals; Benzhydryl Compounds; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Ligands; Macaca mulatta; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Piperazines; Piperidines; Radioligand Assay; Tritium

2001
Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.
    Journal of neurochemistry, 2001, Volume: 76, Issue:4

    Topics: Amino Acid Substitution; Binding, Competitive; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Binding

2001
Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrophysiology; Enzyme Inhibitors; Genistein; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Phenols; Protein-Tyrosine Kinases; Transfection; Tritium; Tyrphostins; Xenopus laevis

2001
Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes.
    Neuroscience research, 2001, Volume: 39, Issue:3

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Sodium Chloride

2001
Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity.
    Life sciences, 2001, Feb-23, Volume: 68, Issue:14

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Bridged Bicyclo Compounds; Chromatography, Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Hypericum; In Vitro Techniques; Male; Norepinephrine; Phloroglucinol; Plants, Medicinal; Rats; Rats, Wistar; Serotonin; Synaptosomes; Terpenes

2001
[(18)F]FDOPA and [(18)F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease.
    Synapse (New York, N.Y.), 2001, Jun-01, Volume: 40, Issue:3

    Topics: Aged; Brain; Caudate Nucleus; Cocaine; Dihydroxyphenylalanine; Dopamine; Down-Regulation; Female; Fluorine Radioisotopes; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Presynaptic Terminals; Putamen; Synaptic Transmission

2001
Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-15, Volume: 21, Issue:8

    Topics: Animals; Autoradiography; Binding Sites; Carrier Proteins; Caudate Nucleus; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Densitometry; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intravenous; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Putamen; Self Administration; Tissue Distribution

2001
Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.
    Psychopharmacology, 2001, Volume: 154, Issue:4

    Topics: Animals; Antiparkinson Agents; Benztropine; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Muscarinic M1; Receptors, Muscarinic; Serotonin Plasma Membrane Transport Proteins; Symporters

2001
Neurotransmitter transporters synthesis and degradation rates.
    Life sciences, 2001, Apr-06, Volume: 68, Issue:19-20

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Half-Life; Injections, Intraventricular; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereotaxic Techniques; Tropanes

2001
Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites.
    Life sciences, 2001, Apr-06, Volume: 68, Issue:19-20

    Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Histidine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Engineering; Protein Structure, Tertiary; Structure-Activity Relationship; Zinc

2001
The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis.
    Journal of neurochemistry, 2001, Volume: 77, Issue:4

    Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Carrier Proteins; Cell Line; Cocaine; Conserved Sequence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kinetics; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Radioligand Assay; Recombinant Proteins; Transfection; Tritium; Tryptophan

2001
Sensitive measurement of positron emitters eluted from HPLC.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2001, Volume: 55, Issue:2

    Topics: Animals; Bismuth; Chromatography, High Pressure Liquid; Cocaine; Humans; Mice; Mice, Inbred Strains; Pyrrolidines; Radiation Monitoring; Receptors, Dopamine; Salicylamides; Tomography, Emission-Computed

2001
The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Benztropine; Binding Sites; Binding, Competitive; Carrier Proteins; Cell Membrane; Cocaine; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Indicators and Reagents; Kinetics; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Models, Molecular; Nerve Tissue Proteins; Protein Conformation

2001
Synthesis and pharmacology of site specific cocaine abuse treatment agents: a new synthetic methodology for methylphenidate analogs based on the Blaise reaction.
    European journal of medicinal chemistry, 2001, Volume: 36, Issue:4

    Topics: Animals; Biochemistry; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Methylphenidate; Molecular Structure; Rats; Structure-Activity Relationship

2001
Methamphetamine-related psychiatric symptoms and reduced brain dopamine transporters studied with PET.
    The American journal of psychiatry, 2001, Volume: 158, Issue:8

    Topics: Adult; Behavior, Addictive; Brain Chemistry; Brief Psychiatric Rating Scale; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellar Cortex; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Nucleus Accumbens; Prefrontal Cortex; Psychoses, Substance-Induced; Putamen; Substance-Related Disorders; Tomography, Emission-Computed

2001
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors.
    Synapse (New York, N.Y.), 2001, Sep-15, Volume: 41, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzazepines; Brain Chemistry; Clomipramine; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulpiride

2001
Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Benzhydryl Compounds; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Drug Evaluation, Preclinical; Isomerism; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship

2001
Peptide derived from insulin with regulatory activity of dopamine transporter.
    Neuropharmacology, 2001, Volume: 41, Issue:4

    Topics: Aminobutyrates; Animals; Carrier Proteins; CHO Cells; Cloning, Molecular; Cocaine; Cricetinae; Dopamine Plasma Membrane Transport Proteins; GABA Plasma Membrane Transport Proteins; Insulin; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Microinjections; Nerve Tissue Proteins; Organic Anion Transporters; Peptides; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra; Synaptosomes

2001
Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia.
    Experimental neurology, 2001, Volume: 171, Issue:2

    Topics: Adult; Aged; Aging; Autoradiography; Basal Ganglia; Caudate Nucleus; Cause of Death; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Nucleus Accumbens; Putamen; Radioligand Assay; Receptors, N-Methyl-D-Aspartate

2001
Decreased striatal dopamine transporter binding in vivo in chronic schizophrenia.
    Schizophrenia research, 2001, Oct-01, Volume: 52, Issue:1-2

    Topics: Adult; Brain Mapping; Chronic Disease; Cocaine; Corpus Striatum; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Psychiatric Status Rating Scales; Radioligand Assay; Schizophrenia; Tomography, Emission-Computed

2001
2'-substituted analogs of cocaine: synthesis and dopamine transporter binding potencies.
    Archiv der Pharmazie, 2001, Volume: 334, Issue:8-9

    Topics: Animals; Brain; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2001
Synthesis and binding affinities of 2 beta-(3-iodoallyloxycarbonyl)-3 beta-(4-substituted-aryl)tropane analogues as ligands for the dopamine transporter studies.
    Bioorganic & medicinal chemistry letters, 2001, Dec-03, Volume: 11, Issue:23

    Topics: Animals; Binding, Competitive; Biochemistry; Cell Membrane; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Inhibitory Concentration 50; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Structure-Activity Relationship; Tropanes

2001
[3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.
    Bioorganic & medicinal chemistry letters, 2001, Dec-17, Volume: 11, Issue:24

    Topics: Animals; Carbazoles; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Nerve Tissue Proteins; Piperazines; Rats

2001
Novel tropane-based irreversible ligands for the dopamine transporter.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Animals; Azides; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; In Vitro Techniques; Isothiocyanates; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Putamen; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes

2001
Ethanol potentiates the function of the human dopamine transporter expressed in Xenopus oocytes.
    Journal of neurochemistry, 2001, Volume: 79, Issue:5

    Topics: Animals; Carrier Proteins; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ethanol; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Kinetics; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Rats; Receptors, Cell Surface; RNA; Xenopus

2001
Ketamine alters the availability of striatal dopamine transporter as measured by [(11)C]beta-CFT and [(11)C]beta-CIT-FE in the monkey brain.
    Synapse (New York, N.Y.), 2001, Dec-15, Volume: 42, Issue:4

    Topics: Anesthetics, Dissociative; Animals; Carbon Radioisotopes; Cerebrovascular Circulation; Cocaine; Contrast Media; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Ketamine; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Time Factors; Tomography, Emission-Computed

2001
Cocaine induction of dopamine transporter trafficking to the plasma membrane.
    Molecular pharmacology, 2002, Volume: 61, Issue:2

    Topics: Animals; Binding, Competitive; Biological Transport; Blotting, Western; Cell Membrane; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Phosphorylation; Radioligand Assay; RNA, Messenger; Second Messenger Systems; Serotonin; Subcellular Fractions; Transfection; Tritium; Tumor Cells, Cultured

2002
Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for neurotoxicity.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Animals; Biological Transport; Body Temperature; Cell Membrane; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hallucinogens; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neuropeptides; Neurotoxins; Rats; Rats, Sprague-Dawley; Synaptic Vesicles; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2002
Effects of GBR 12909, WIN 35,428 and indatraline on cocaine self-administration and cocaine seeking in rats.
    Psychopharmacology, 2002, Volume: 160, Issue:3

    Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indans; Male; Methylamines; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Self Administration

2002
Birth insult and stress interact to alter dopamine transporter binding in rat brain.
    Neuroreport, 2002, Feb-11, Volume: 13, Issue:2

    Topics: Aging; Animals; Brain; Cesarean Section; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fetal Hypoxia; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Reference Values; Stress, Physiological

2002
Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism.
    Molecular pharmacology, 2002, Volume: 61, Issue:4

    Topics: Amino Acid Substitution; Animals; Binding, Competitive; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Drug Resistance; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Motor Proteins; Mutation; Nerve Tissue Proteins; Transfection; Tritium

2002
Is Na(+) required for the binding of dopamine, amphetamine, tyramine, and octopamine to the human dopamine transporter?
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:4

    Topics: Amphetamine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Octopamine; Sodium; Substrate Specificity; Tyramine

2002
The functional domains of dopamine transporter for cocaine analog, CFT binding.
    Experimental & molecular medicine, 2002, Mar-31, Volume: 34, Issue:1

    Topics: Animals; Cattle; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins

2002
Dopamine transport function is elevated in cocaine users.
    Journal of neurochemistry, 2002, Volume: 81, Issue:2

    Topics: Adult; Animals; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cryopreservation; Delirium; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Postmortem Changes; Synaptosomes; Time Factors

2002
Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.
    Bioorganic & medicinal chemistry letters, 2002, Jul-08, Volume: 12, Issue:13

    Topics: Binding Sites; Biphenyl Compounds; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ligands; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine; Serotonin; Structure-Activity Relationship; Thiazoles

2002
Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.
    Journal of neurochemistry, 2002, Volume: 81, Issue:6

    Topics: Binding, Competitive; Cations; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Humans; Lithium; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Potassium; Protons; Sodium

2002
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys.
    Synapse (New York, N.Y.), 2002, Volume: 45, Issue:1

    Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed

2002
Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2002, Volume: 57, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Cocaine; Dopamine Agents; Humans; Levodopa; Male; Methylphenidate; Mice; Mice, Inbred ICR; Organotechnetium Compounds; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Tropanes

2002
Effects of SCH 23390 and eticlopride on cocaine-seeking produced by cocaine and WIN 35,428 in rats.
    Psychopharmacology, 2003, Volume: 168, Issue:1-2

    Topics: Animals; Behavior, Addictive; Benzazepines; Cocaine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides

2003
Ceramide-induced alterations in dopamine transporter function.
    European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2

    Topics: Animals; Binding, Competitive; Ceramides; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes; Tritium

2003
Assessment of mazindane, a pro-drug form of mazindol, in assays used to define cocaine treatment agents.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Analysis of Variance; Animals; Binding, Competitive; Cell Membrane; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Isoindoles; Macaca mulatta; Male; Mazindol; Mice; Motor Activity; Neurotransmitter Agents; Proadifen; Rats; Rats, Sprague-Dawley; Tritium

2003
Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats.
    Neuroendocrinology, 2003, Volume: 77, Issue:2

    Topics: Amphetamine; Animals; Blood Glucose; Cocaine; Diabetes Mellitus, Experimental; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Eating; Insulin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Pancrelipase; Rats; Rats, Sprague-Dawley; Self Administration; Streptozocin; Synaptosomes

2003
Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter.
    The Journal of biological chemistry, 2003, Aug-15, Volume: 278, Issue:33

    Topics: Amino Acid Sequence; Animals; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Extracellular Space; Humans; Indicators and Reagents; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Conformation; Protein Structure, Tertiary; Radioligand Assay; Sodium; Tritium; Zinc

2003
Age-related changes of the [11C]CFT binding to the striatal dopamine transporters in the Fischer 344 rats: a PET study.
    Annals of nuclear medicine, 2003, Volume: 17, Issue:3

    Topics: Age Factors; Aging; Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Metabolic Clearance Rate; Nerve Tissue Proteins; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution

2003
Na+ stimulates binding of dopamine to the dopamine transporter in cells but not in cell-free preparations.
    Journal of neurochemistry, 2003, Volume: 86, Issue:3

    Topics: Binding, Competitive; Cell Line; Cell Membrane; Cell-Free System; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Kidney; Meglumine; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Nerve Tissue Proteins; Potassium; Sodium; Sucrose

2003
Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Binding Sites; Body Temperature; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Homovanillic Acid; Male; Methamphetamine; Motor Activity; Neostriatum; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tetrabenazine; Time Factors; Tritium

2003
Acquisition of an appetitive behavior prevents development of stress-induced neurochemical modifications in rat nucleus accumbens.
    Journal of neuroscience research, 2003, Aug-15, Volume: 73, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Analysis of Variance; Animals; Appetite; Behavior, Animal; Benzazepines; Binding Sites; Brain Chemistry; Carbohydrates; Cell Count; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Escape Reaction; Male; Maze Learning; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stress, Physiological; Time Factors; Tritium; Vanilla

2003
Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:12

    Topics: Animals; Binding Sites; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Head; Individuality; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors

2003
Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms.
    The American journal of psychiatry, 2003, Volume: 160, Issue:9

    Topics: Adult; Amphetamine-Related Disorders; Amygdala; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Frontal Lobe; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Prefrontal Cortex; Psychoses, Substance-Induced; Tomography, Emission-Computed

2003
Unchanged striatal dopamine transporter availability in narcolepsy: a PET study with [11C]-CFT.
    Acta neurologica Scandinavica, 2004, Volume: 109, Issue:1

    Topics: Adolescent; Adult; Case-Control Studies; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Narcolepsy; Nerve Tissue Proteins; Putamen; Tomography, Emission-Computed

2004
Binding of cocaine-like radioligands to the dopamine transporter at 37 degrees C: effect of Na+ and substrates.
    Journal of neuroscience methods, 2003, Dec-30, Volume: 131, Issue:1-2

    Topics: Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Radioligand Assay; Sodium; Temperature; Tritium

2003
Structure-activity relationships for substrate recognition by the human dopamine transporter.
    Biochemical pharmacology, 2004, Jan-15, Volume: 67, Issue:2

    Topics: Binding, Competitive; Biological Transport; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Structure-Activity Relationship

2004
The self-administration of WIN 35,428 and cocaine: comparisons of satiety threshold and elimination half-life in rats.
    European journal of pharmacology, 2004, Jan-12, Volume: 483, Issue:2-3

    Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Half-Life; Male; Rats; Rats, Sprague-Dawley; Satiety Response; Self Administration

2004
Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:2

    Topics: Animals; Antiparkinson Agents; Benztropine; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley

2004
Influence of early postnatal rearing conditions on mesocorticolimbic dopamine and behavioural responses to psychostimulants and stressors in adult rats.
    The European journal of neuroscience, 2004, Volume: 19, Issue:7

    Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Binding Sites; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; In Situ Hybridization; Male; Maternal Deprivation; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine; RNA, Messenger; Stress, Psychological; Tetrahydronaphthalenes; Tritium

2004
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
    Journal of neurochemistry, 2004, Volume: 89, Issue:4

    Topics: Amino Acid Substitution; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Muscarinic Antagonists; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Piperazines; Protein Binding; Sodium; Structure-Activity Relationship; Zinc

2004
Reinforcing effect of pseudoephedrine isomers and the mechanism of action.
    European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3

    Topics: Animals; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ephedrine; Humans; Infusion Pumps; Isomerism; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin Plasma Membrane Transport Proteins; Symporters; Tritium

2004
Role of the dopamine transporter in the differential cocaine-induced locomotor activation of inbred long-sleep and short-sleep mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:10

    Topics: Animals; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Habituation, Psychophysiologic; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Neostriatum; Nerve Tissue Proteins; Sleep

2004
Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease.
    Annals of neurology, 2004, Volume: 56, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain; Carbon Radioisotopes; Cocaine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dopamine Uptake Inhibitors; Hazardous Substances; Humans; Inclusion Bodies; Male; Molecular Structure; Multienzyme Complexes; Oligopeptides; Parkinson Disease, Secondary; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed

2004
Identification and characterization of metallothionein-1 and -2 gene expression in the context of (+/-)3,4-methylenedioxymethamphetamine-induced toxicity to brain dopaminergic neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Aug-11, Volume: 24, Issue:32

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Blotting, Northern; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Illicit Drugs; Male; Metallothionein; Methamphetamine; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Time Factors

2004
Mapping dopamine function in primates using pharmacologic magnetic resonance imaging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Oct-27, Volume: 24, Issue:43

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Brain; Brain Mapping; Cerebrovascular Circulation; Cocaine; Dopamine; Dopamine Agents; Macaca fascicularis; Magnetic Resonance Imaging; Motor Activity; Parkinsonian Disorders; Positron-Emission Tomography; Radioligand Assay

2004
Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters.
    Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24

    Topics: Alkenes; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship

2004
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.
    European journal of pharmacology, 2004, Dec-03, Volume: 506, Issue:1

    Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Biological Transport; Cell Line; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nerve Tissue Proteins; Norepinephrine; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism; Synaptosomes; Tritium

2004
Enhanced binding of dopamine D1 receptors in caudate-putamen subregions in High-Yawning Sprague-Dawley rats.
    Synapse (New York, N.Y.), 2005, Volume: 56, Issue:2

    Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Neostriatum; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Spiperone; Tritium; Yawning

2005
Purification of carbon-11 PET radiotracers from unlabeled precursors by preparative HPLC and SPE.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:9

    Topics: Carbon Radioisotopes; Chemical Fractionation; Choline; Chromatography, High Pressure Liquid; Cocaine; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals

2005
Involvement of dopamine receptors in cocaine-induced genital reflexes after paradoxical sleep deprivation.
    Behavioural brain research, 2005, May-07, Volume: 160, Issue:1

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Brain; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Penile Erection; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine; Sleep Deprivation; Sleep, REM; Tritium

2005
Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex.
    Behavioural brain research, 2005, May-28, Volume: 160, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Mapping; Clonidine; Cocaine; Cognition Disorders; Discrimination Learning; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Macaca mulatta; Male; Membrane Proteins; Memory; Nerve Tissue Proteins; Neuropsychological Tests; Prazosin; Prefrontal Cortex; Radioligand Assay; Receptors, Catecholamine; Statistics as Topic; Tritium

2005
Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Amino Acid Substitution; Animals; Aspartic Acid; Benztropine; Binding, Competitive; CHO Cells; Cocaine; Cricetinae; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Immunohistochemistry; Kinetics; Ligands; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Transfection

2005
Acute NMDA receptor antagonism induces biphasic striatal utilization of L-[beta-11C]DOPA: PET studies in the conscious monkey brain.
    Synapse (New York, N.Y.), 2005, Volume: 57, Issue:2

    Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Cocaine; Consciousness; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Levodopa; Macaca mulatta; Male; Neural Pathways; Positron-Emission Tomography; Presynaptic Terminals; Raclopride; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2005
Proline mutations induce negative-dosage effects on uptake velocity of the dopamine transporter.
    Journal of neurochemistry, 2005, Volume: 94, Issue:1

    Topics: Amino Acid Substitution; Animals; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Proline; Thermodynamics; Tyramine

2005
Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2

    Topics: Animals; Benztropine; Binding, Competitive; Brain; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Guanidines; Histamine; Histamine Agonists; Histamine H1 Antagonists; In Vitro Techniques; Male; Methylhistamines; Motor Activity; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Tropanes

2005
Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates.
    Neuropharmacology, 2005, Volume: 49, Issue:6

    Topics: Analysis of Variance; Animals; Binding, Competitive; Calcium; Cell Line; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gramicidin; Humans; Male; Membrane Potentials; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sodium; Synaptosomes; Tritium

2005
Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation.
    Neuropharmacology, 2005, Volume: 49, Issue:6

    Topics: Amphetamine; Animals; Biotin; Biotinylation; Cell Line; Cocaine; Corpus Striatum; Diagnostic Imaging; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Administration Schedule; Electrophoresis, Polyacrylamide Gel; Endocytosis; Exocytosis; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Protein Binding; Protein Transport; Rats; Subcellular Fractions; Synaptosomes; Time Factors; Transfection; Tritium

2005
Acute manganese administration alters dopamine transporter levels in the non-human primate striatum.
    Neurotoxicology, 2006, Volume: 27, Issue:2

    Topics: Animals; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Kinetics; Male; Manganese; Manganese Compounds; Membranes; Neostriatum; Papio; Positron-Emission Tomography; Presynaptic Terminals; Rats; Rats, Long-Evans; Sulfates

2006
HIV-1 Tat neurotoxicity in primary cultures of rat midbrain fetal neurons: changes in dopamine transporter binding and immunoreactivity.
    Neuroscience letters, 2006, Mar-13, Volume: 395, Issue:3

    Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epitopes; Female; Gene Products, tat; HIV-1; Immunohistochemistry; Mesencephalon; Neurons; Neurotoxins; Phosphopyruvate Hydratase; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; tat Gene Products, Human Immunodeficiency Virus

2006
Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine.
    Bioorganic & medicinal chemistry, 2006, Jun-01, Volume: 14, Issue:11

    Topics: Animals; Benzylamines; Binding, Competitive; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Norepinephrine Plasma Membrane Transport Proteins; Pyrans; Rats; Reference Standards; Sensitivity and Specificity; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship

2006
Characterization of the neuronal dopamine transporter DAT in human blood platelets.
    Neuroscience letters, 2006, May-22, Volume: 399, Issue:3

    Topics: Blood Platelets; Blotting, Northern; Blotting, Western; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Humans; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins

2006
Dopamine uptake and cocaine binding mechanisms: the involvement of charged amino acids from the transmembrane domains of the human dopamine transporter.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Transfection; Tritium

2006
3-Aza-6,8-dioxabicyclo[3.2.1]octanes as new enantiopure heteroatom-rich tropane-like ligands of human dopamine transporter.
    Bioorganic & medicinal chemistry, 2006, Aug-01, Volume: 14, Issue:15

    Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; CHO Cells; Citalopram; Cocaine; Cricetinae; Dopamine Plasma Membrane Transport Proteins; Humans; Ligands; Models, Molecular; Molecular Conformation; Recombinant Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tropanes

2006
One hour, but not six hours, of daily access to self-administered cocaine results in elevated levels of the dopamine transporter.
    Brain research, 2006, Jun-20, Volume: 1095, Issue:1

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprague-Dawley; Self Administration; Time Factors; Tritium

2006
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease.
    Brain research, 2006, Jun-20, Volume: 1095, Issue:1

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinson Disease; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subthalamic Nucleus; Tritium

2006
Binding of 3H-WIN-35,428 and 125I-RTI-121 to human platelet membranes.
    Neurochemical research, 2006, Volume: 31, Issue:3

    Topics: Adult; Blood Platelets; Cell Membrane; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; In Vitro Techniques; Iodine Radioisotopes; Ligands; Male; Protein Binding

2006
Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2

    Topics: Animals; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Macaca fascicularis; Male; Parkinsonian Disorders; Quinolines; Receptors, Dopamine D2; Receptors, Dopamine D3

2006
Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge.
    Synapse (New York, N.Y.), 2006, Volume: 60, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amphetamine-Related Disorders; Animals; Body Temperature; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Male; Methamphetamine; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley

2006
Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors.
    Neuropharmacology, 2006, Volume: 51, Issue:4

    Topics: Aconitine; Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotinic Agonists; Nicotinic Antagonists; Radioligand Assay; Reactive Oxygen Species; Receptors, Nicotinic; Synaptosomes; Tritium

2006
In vivo presynaptic and postsynaptic striatal dopamine functions in idiopathic normal pressure hydrocephalus.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:4

    Topics: Aged; Cerebral Ventricles; Cocaine; Cognition; Dopamine; Dopamine Antagonists; Female; Humans; Hydrocephalus, Normal Pressure; Magnetic Resonance Imaging; Male; Memory; Mesencephalon; Middle Aged; Neostriatum; Neuropsychological Tests; Nucleus Accumbens; Positron-Emission Tomography; Presynaptic Terminals; Putamen; Raclopride; Receptors, Dopamine D2; Synapses

2007
Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters.
    Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2

    Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Caudate Nucleus; Chromatography, Thin Layer; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Indicators and Reagents; Macaca fascicularis; Macaca mulatta; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Oxidation-Reduction; Putamen; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship

2007
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier.
    Journal of the neurological sciences, 2007, Jan-31, Volume: 252, Issue:2

    Topics: Adult; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Antagonists; Gaucher Disease; Heterozygote; Humans; Male; Neurons; Parkinson Disease; Positron-Emission Tomography; Raclopride

2007
CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum.
    Journal of neurochemistry, 2007, Volume: 101, Issue:2

    Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Cannabinoids; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Piperidines; Presynaptic Terminals; Pyrazoles; Receptor, Cannabinoid, CB1; Synaptosomes

2007
Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system.
    Experimental neurology, 2007, Volume: 204, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dieldrin; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Oxidative Stress; Protein Carbonylation; Substantia Nigra

2007
Evaluation of four pyridine analogs to characterize 6-OHDA-induced modulation of mGluR5 function in rat brain using microPET studies.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:9

    Topics: Adrenergic Agents; Animals; Brain; Cocaine; Functional Laterality; Image Processing, Computer-Assisted; Male; Oxidopamine; Parkinsonian Disorders; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

2007
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.
    Journal of medicinal chemistry, 2007, May-31, Volume: 50, Issue:11

    Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Male; Methylphenidate; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship

2007
Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease.
    Journal of neurology, 2007, Volume: 254, Issue:1

    Topics: Aged; Cocaine; Corpus Striatum; Denervation; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Olfaction Disorders; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra

2007
Inhibitive effects of Fructus Psoraleae extract on dopamine transporter and noradrenaline transporter.
    Journal of ethnopharmacology, 2007, Jul-25, Volume: 112, Issue:3

    Topics: Animals; Binding, Competitive; Biological Transport; Cell Survival; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Motor Activity; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Plant Extracts; Psoralea; Rats; Reserpine; Seeds; Synaptosomes; Transfection

2007
Modulation of dopaminergic and glutamatergic brain function: PET studies on parkinsonian rats.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:7

    Topics: Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Hippocampus; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Oxidopamine; Parkinsonian Disorders; Positron-Emission Tomography; Pyridines; Raclopride; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Substantia Nigra; Tyrosine 3-Monooxygenase

2007
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease.
    Journal of neuropathology and experimental neurology, 2007, Volume: 66, Issue:7

    Topics: Analysis of Variance; Animals; Autoradiography; Cell Transplantation; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Extremities; Functional Laterality; Humans; Male; Motor Neuron Disease; Parkinson Disease; Pigment Epithelium of Eye; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors; Transplantation, Heterologous

2007
Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:6

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain; Brain Chemistry; Central Nervous System Stimulants; Chlorocebus aethiops; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Neurotoxicity Syndromes; Protein Binding; Raclopride; Social Behavior; Tritium

2008
Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression.
    The European journal of neuroscience, 2007, Volume: 26, Issue:3

    Topics: Aconitine; Animals; Behavior, Animal; Binding, Competitive; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Exploratory Behavior; Male; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenotype; Prefrontal Cortex; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Synaptosomes; Tobacco Use Disorder

2007
Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease.
    Neuroscience letters, 2007, Sep-13, Volume: 424, Issue:3

    Topics: Aged; Biomarkers; Cocaine; Female; Humans; Isotopes; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Striatonigral Degeneration

2007
Parkin disrupts the alpha-synuclein/dopamine transporter interaction: consequences toward dopamine-induced toxicity.
    Journal of molecular neuroscience : MN, 2007, Volume: 32, Issue:3

    Topics: alpha-Synuclein; Binding Sites; Cell Line; Cell Membrane; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Kinetics; Microscopy, Confocal; Transfection; Ubiquitin-Protein Ligases

2007
Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.
    Molecular pharmacology, 2008, Volume: 73, Issue:3

    Topics: Alanine; Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Cocaine; COS Cells; Data Interpretation, Statistical; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Mesylates; Motor Activity; Protein Binding; Protein Conformation; Rats; Rats, Sprague-Dawley; Transfection

2008
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
    Journal of neurochemistry, 2008, Volume: 105, Issue:1

    Topics: Animals; Autoradiography; Brain; Carbon Isotopes; Carrier Proteins; Cocaine; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Glial Fibrillary Acidic Protein; Isoquinolines; Male; Neurons; Papio anubis; Parkinsonian Disorders; Positron-Emission Tomography; Raclopride; Tetrabenazine; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2008
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users.
    Synapse (New York, N.Y.), 2008, Volume: 62, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Cocaine; Cognition; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Male; Methamphetamine; Middle Aged; Neuropsychological Tests; Parkinson Disease, Secondary; Positron-Emission Tomography

2008
Presence and characterization of the dopamine transporter in human resting lymphocytes.
    Neurochemical research, 2008, Volume: 33, Issue:6

    Topics: Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Lymphocytes; Male; Tritium

2008
Altered dopamine receptor and dopamine transporter binding and tyrosine hydroxylase mRNA expression following perinatal NMDA receptor blockade.
    Neurochemical research, 2008, Volume: 33, Issue:7

    Topics: Animals; Autoradiography; Brain Chemistry; Cocaine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Female; In Situ Hybridization; Phencyclidine; Pregnancy; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tyrosine 3-Monooxygenase

2008
Ex vivo evaluation of N-(3-[18F]fluoropropyl)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)nortropane in rats.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:2

    Topics: Animals; Binding, Competitive; Bone and Bones; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluorine Radioisotopes; Limbic System; Male; Nortropanes; Piperazines; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution

2008
The binding sites for cocaine and dopamine in the dopamine transporter overlap.
    Nature neuroscience, 2008, Volume: 11, Issue:7

    Topics: Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Structure-Activity Relationship; Time Factors; Transfection

2008
Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons.
    Neurotoxicology, 2008, Volume: 29, Issue:6

    Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Embryo, Mammalian; HIV Envelope Protein gp120; Mesencephalon; Neurons; Piperazines; Protein Binding; Rats; Serotonin Plasma Membrane Transport Proteins; tat Gene Products, Human Immunodeficiency Virus

2008
Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration.
    Neuropharmacology, 2008, Volume: 55, Issue:5

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Autoradiography; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Multivariate Analysis; Protein Binding; Random Allocation; Rats; Rats, Inbred Lew; Reinforcement, Psychology; Self Administration; Time Factors; Tritium

2008
Abstinence from chronic cocaine self-administration alters striatal dopamine systems in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:5

    Topics: Animals; Benzazepines; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Raclopride; Receptors, Dopamine D1; Self Administration; Tritium

2009
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
    Journal of neurochemistry, 2008, Volume: 107, Issue:4

    Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan

2008
Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity.
    Neuroscience letters, 2008, Dec-05, Volume: 447, Issue:1

    Topics: Aged; Carbon Isotopes; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hippocampus; Humans; Male; Mental Status Schedule; Middle Aged; Models, Biological; Neural Pathways; Olfaction Disorders; Parkinson Disease; Radionuclide Imaging

2008
Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner.
    Neuropharmacology, 2009, Volume: 56, Issue:2

    Topics: Amphetamine; Animals; Binding, Competitive; Cell Line; Chlorides; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Histidine; Humans; Lysine; Male; Membrane Potentials; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Trace Elements; Transfection; Zinc Sulfate

2009
Dopaminergic neurons derived from BG01V2, a variant of human embryonic stem cell line BG01.
    Restorative neurology and neuroscience, 2008, Volume: 26, Issue:6

    Topics: Actins; Bromodeoxyuridine; Cell Differentiation; Cell Line; Cell Proliferation; Chromosomes, Human, Pair 17; Cocaine; Coculture Techniques; Dopamine; Dopamine Plasma Membrane Transport Proteins; Embryonic Stem Cells; Humans; Membrane Potentials; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Otx Transcription Factors; Patch-Clamp Techniques; Protein Binding; Time Factors; Tritium; Tyrosine 3-Monooxygenase

2008
Regional analysis of age-related decline in dopamine transporters and dopamine D2-like receptors in human striatum.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:4

    Topics: Adult; Age Factors; Aged; Aging; Carbon Isotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Young Adult

2009
In vitro binding assays using (3)H nisoxetine and (3)H WIN 35,428 reveal selective effects of gonadectomy and hormone replacement in adult male rats on norepinephrine but not dopamine transporter sites in the cerebral cortex.
    Neuroscience, 2009, Mar-03, Volume: 159, Issue:1

    Topics: Animals; Cerebral Cortex; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Estradiol; Fluoxetine; Gonadal Hormones; Male; Norepinephrine Plasma Membrane Transport Proteins; Orchiectomy; Protein Binding; Rats; Rats, Sprague-Dawley; Testosterone Propionate; Time Factors; Tritium

2009
Dopamine transporter binding in rat striatum: a comparison of [O-methyl-11C]beta-CFT and [N-methyl-11C]beta-CFT.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:1

    Topics: Animals; Carbon Radioisotopes; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Neostriatum; Nitrogen; Oxygen; Positron-Emission Tomography; Protein Binding; Radiochemistry; Rats; Rats, Sprague-Dawley

2009
Decreased brain dopamine cell numbers in human cocaine users.
    Psychiatry research, 2009, Aug-15, Volume: 168, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Count; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Male; Mesencephalon; Middle Aged; Neurons; Plant Lectins; Protein Binding; Tritium; Tyrosine 3-Monooxygenase; Young Adult

2009
Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:7

    Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Embryonic Stem Cells; Levodopa; Macaca fascicularis; Methamphetamine; Movement Disorders; Neurons; Parkinson Disease; Positron-Emission Tomography; Putamen; Raclopride; Tyrosine 3-Monooxygenase

2009
In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Delta 3,2-hydroxybakuchiol isolated from Psoralea corylifolia (L.).
    Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Cell Line; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Agents; Humans; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Norepinephrine; Parkinson Disease; Phenols; Psoralea; Rats; Rats, Sprague-Dawley; Synaptosomes; Tyrosine 3-Monooxygenase

2009
HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Binding Sites; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Leucine; Male; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Surface Plasmon Resonance; Synaptosomes; tat Gene Products, Human Immunodeficiency Virus

2009
Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-27, Volume: 29, Issue:21

    Topics: Alanine; Animals; Animals, Newborn; Cells, Cultured; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dynamins; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Humans; Indoles; Lysine; Maleimides; Mesencephalon; Mutation; Neurons; Phorbol Esters; Protein Transport; rab5 GTP-Binding Proteins; Rats; Receptors, Transferrin; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2009
Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:3

    Topics: Animals; Benztropine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Microdialysis; Nucleus Accumbens

2009
Expanding the clinical phenotype of SNCA duplication carriers.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Sep-15, Volume: 24, Issue:12

    Topics: Adult; Aged; alpha-Synuclein; Brain; Carbon Isotopes; Chromosome Mapping; Cocaine; Family Health; Female; Fluorodeoxyglucose F18; Gene Dosage; Gene Duplication; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Parkinson Disease; Phenotype; Positron-Emission Tomography; Raclopride; REM Sleep Behavior Disorder; Sensory Thresholds; Smell; Young Adult

2009
Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity.
    Molecular pharmacology, 2009, Volume: 76, Issue:4

    Topics: Animals; Cells, Cultured; Cocaine; Corpus Striatum; Cyclin-Dependent Kinase 5; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Humans; Indoles; Male; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Swine; Synaptosomes

2009
Analysis of SCA2 and SCA3/MJD repeats in Parkinson's disease in mainland China: genetic, clinical, and positron emission tomography findings.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Oct-15, Volume: 24, Issue:13

    Topics: Adult; Aged; Ataxin-3; Ataxins; Carbon Isotopes; China; Cocaine; DNA Mutational Analysis; Family Health; Female; Humans; Male; Middle Aged; Nerve Tissue Proteins; Nuclear Proteins; Parkinson Disease; Positron-Emission Tomography; Repressor Proteins; Trinucleotide Repeat Expansion

2009
Evaluation of nigrostriatal damage and its change over weeks in a rat model of Parkinson's disease: small animal positron emission tomography studies with [(11)C]beta-CFT.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:8

    Topics: Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Disease Models, Animal; Humans; Male; Parkinsonian Disorders; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar

2009
Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Guanidines; Male; Morpholines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement Schedule; Reward; Self Administration

2010
Alterations of the dopamine transporter in resting lymphocytes of patients with different psychotic disorders.
    Psychiatry research, 2010, Jan-30, Volume: 175, Issue:1-2

    Topics: Adolescent; Adult; Antipsychotic Agents; Cell Membrane; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Lymphocytes; Male; Protein Binding; Psychotic Disorders; Statistics as Topic; Tritium; Young Adult

2010
Objective and quantitative evaluation of motor function in a monkey model of Parkinson's disease.
    Journal of neuroscience methods, 2010, Jul-15, Volume: 190, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Mapping; Carbon Radioisotopes; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Macaca fascicularis; Parkinsonian Disorders; Positron-Emission Tomography; Severity of Illness Index; Video Recording

2010
Progression from unilateral to bilateral parkinsonism in early Parkinson disease: implication of mesocortical dopamine dysfunction by PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:8

    Topics: Adult; Aged; Cerebral Cortex; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Regression Analysis

2010
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Benztropine; Binding, Competitive; Cell Line, Tumor; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Mice; Mice, 129 Strain; Mice, Inbred Strains; Mice, Knockout; Neuroblastoma; Piperazines; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Selective Serotonin Reuptake Inhibitors; Sodium; Triprolidine

2010
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
    Neurochemistry international, 2011, Volume: 58, Issue:1

    Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Paroxetine; PC12 Cells; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes

2011
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.
    Molecular pharmacology, 2011, Volume: 79, Issue:3

    Topics: Amphetamine; Benztropine; Binding Sites; Biotinylation; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Fluoxetine; HEK293 Cells; Humans; Immunoblotting; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Pharmacokinetics; Protein Conformation

2011
Effect of environmental enrichment on methylphenidate-induced locomotion and dopamine transporter dynamics.
    Behavioural brain research, 2011, May-16, Volume: 219, Issue:1

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Environment; Male; Methylphenidate; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2011
Effects of hypoxic-ischemic brain injury on striatal dopamine transporter in newborn piglets: evaluation of 11C-CFT PET/CT for DAT quantification.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:8

    Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Case-Control Studies; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hypoxia-Ischemia, Brain; Male; Multimodal Imaging; Positron-Emission Tomography; Swine; Tomography, X-Ray Computed

2011
Striatal dopamine transporter availability in unmedicated bipolar disorder.
    Bipolar disorders, 2011, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Bipolar Disorder; Carbon Isotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Psychiatric Status Rating Scales; Young Adult

2011
Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; Anisoles; Antipsychotic Agents; Carbazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Molecular Targeted Therapy; Oxalates; Piperidines; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement, Psychology; Self Administration

2011
Characterization of [³H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive.
    Journal of neuroscience methods, 2012, Jan-15, Volume: 203, Issue:1

    Topics: Binding, Competitive; Cocaine; Fluoxetine; HEK293 Cells; Humans; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Radiopharmaceuticals; Tritium

2012
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.
    Journal of neurochemistry, 2012, Volume: 120, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists

2012
Synthesis and structure-activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters.
    Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8

    Topics: Bridged Bicyclo Compounds; Carboxylic Acids; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Esters; Humans; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship

2012
Benign hereditary chorea: dopaminergic brain imaging in patients with a novel intronic NKX2.1 gene mutation.
    Journal of neurology, 2013, Volume: 260, Issue:1

    Topics: Adult; Brain; Brain Mapping; Chorea; Cocaine; DNA Mutational Analysis; Dopamine; Dopamine Antagonists; Family Health; Female; Humans; Male; Middle Aged; Mutation; Nuclear Proteins; Positron-Emission Tomography; Raclopride; Thyroid Nuclear Factor 1; Transcription Factors

2013
The food reaching test: a sensitive test of behavioral improvements by deep brain stimulation in MPTP-treated monkey.
    Neuroscience research, 2012, Volume: 74, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Deep Brain Stimulation; Dihydroxyphenylalanine; Dopamine; Feeding Behavior; Hypokinesia; Macaca fascicularis; Magnetic Resonance Imaging; Male; MPTP Poisoning; Psychomotor Performance; Radionuclide Imaging; Sensitivity and Specificity; Severity of Illness Index; Single-Blind Method; Subthalamic Nucleus; Time Factors; Treatment Outcome; Tremor

2012
Imaging striatal dopaminergic function in phospholipase A2 group VI-related parkinsonism.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:13

    Topics: Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Group VI Phospholipases A2; Humans; Male; Parkinsonian Disorders; Positron-Emission Tomography; Young Adult

2012
Validation of nigrostriatal positron emission tomography measures: critical limits.
    Annals of neurology, 2013, Volume: 73, Issue:3

    Topics: Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Fluorodeoxyglucose F18; Macaca mulatta; Magnetic Resonance Imaging; Male; MPTP Poisoning; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Reproducibility of Results; Substantia Nigra; Tetrabenazine

2013
Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness.
    Synapse (New York, N.Y.), 2013, Volume: 67, Issue:10

    Topics: Animals; Biological Transport, Active; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Deletion; Locomotion; Mice; Protein Binding; Tyrosine 3-Monooxygenase

2013
Subanesthetic doses of ketamine transiently decrease serotonin transporter activity: a PET study in conscious monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:13

    Topics: Analgesics; Analysis of Variance; Animals; Benzylamines; Brain; Carbon Isotopes; Cocaine; Consciousness; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; Image Processing, Computer-Assisted; Ketamine; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Positron-Emission Tomography; Serotonin Plasma Membrane Transport Proteins

2013
Non-dioxin-like PCBs inhibit [(3)H]WIN-35,428 binding to the dopamine transporter: a structure-activity relationship study.
    Neurotoxicology, 2013, Volume: 39

    Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environmental Pollutants; Inhibitory Concentration 50; Male; Models, Chemical; Polychlorinated Biphenyls; Principal Component Analysis; Protein Binding; Rats; Rats, Wistar; Structure-Activity Relationship; Synaptosomes; Tritium

2013
Relation between microPET imaging and rotational behavior in a parkinsonian rat model induced by medial forebrain bundle axotomy.
    Behavioural brain research, 2014, May-15, Volume: 265

    Topics: Animals; Apomorphine; Axotomy; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Functional Laterality; Male; Medial Forebrain Bundle; Parkinson Disease; Raclopride; Radionuclide Imaging; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2014
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Aug-04, Volume: 53

    Topics: Animals; Antidepressive Agents; Citalopram; Cocaine; Depression; Disease Models, Animal; Female; Fluoxetine; Male; Medicine, Chinese Traditional; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Saponins; Swimming; Tritium

2014
In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment.
    Brain research, 2014, Jul-07, Volume: 1571

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Functional Laterality; Macaca; Male; Neurons; Parkinsonian Disorders; Positron-Emission Tomography; Protein Binding; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2014
Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities.
    Journal of neurochemistry, 2015, Volume: 133, Issue:2

    Topics: Binding, Competitive; Biotinylation; Cocaine; Computer Simulation; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mutation; Protein Binding; Protein Subunits; Regression Analysis; Structure-Activity Relationship; Transfection; Tritium

2015
Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2015, Volume: 10, Issue:1

    Topics: Animals; Binding Sites; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Lysine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Conformation; tat Gene Products, Human Immunodeficiency Virus; Tyrosine

2015
Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Binding, Competitive; Caudate Nucleus; Cocaine; Dextroamphetamine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ligands; Male; Rats; Synaptosomes

2015
HIV-1 transgenic rats display an increase in [(3)H]dopamine uptake in the prefrontal cortex and striatum.
    Journal of neurovirology, 2016, Volume: 22, Issue:3

    Topics: AIDS Dementia Complex; Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Expression; HIV-1; Kinetics; Male; Prefrontal Cortex; Rats; Rats, Inbred F344; Rats, Transgenic; Synaptosomes; tat Gene Products, Human Immunodeficiency Virus; Tritium

2016
Onset-related subtypes of Parkinson's disease differ in the patterns of striatal dopaminergic dysfunction: A positron emission tomography study.
    Parkinsonism & related disorders, 2015, Volume: 21, Issue:12

    Topics: Adult; Age of Onset; Aged; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Humans; Male; Middle Aged; Neuroimaging; Organ Specificity; Parkinson Disease; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Tissue Distribution

2015
Suite PET/CT neuroimaging for the diagnosis of Parkinson's disease: statistical parametric mapping analysis.
    Nuclear medicine communications, 2017, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Mapping; Case-Control Studies; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Glucose; Humans; Male; Middle Aged; Molecular Imaging; Parkinson Disease; Positron Emission Tomography Computed Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Young Adult

2017
Chronic oral methylphenidate treatment reversibly increases striatal dopamine transporter and dopamine type 1 receptor binding in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:5

    Topics: Administration, Oral; Animals; Autoradiography; Benzazepines; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Male; Methylphenidate; Radiopharmaceuticals; Rats, Inbred SHR; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tritium

2017
Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:2

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Reward; RGS Proteins; Signal Transduction; Ventral Striatum

2018
Multi-modality molecular imaging characteristics of dementia with Lewy bodies.
    The Journal of international medical research, 2018, Volume: 46, Issue:6

    Topics: Aged; Aged, 80 and over; Aniline Compounds; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Humans; Lewy Body Disease; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Imaging; Multimodal Imaging; Neuroimaging; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles

2018
Tamoxifen Directly Interacts with the Dopamine Transporter.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 367, Issue:1

    Topics: Amphetamine; Animals; Binding Sites; Cell Line; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Rats; Swine; Synaptosomes; Tamoxifen

2018
Hypnic Headache with Dopaminergic Neuron Dysfunction: New Insight from a Rare Case.
    Pain medicine (Malden, Mass.), 2019, 08-01, Volume: 20, Issue:8

    Topics: Benserazide; Brain; Cocaine; Dopamine Agents; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Drug Combinations; Fluorodeoxyglucose F18; Headache Disorders, Primary; Humans; Levodopa; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Putamen; Radiopharmaceuticals

2019
Positron emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for the severity assessment of Parkinson disease.
    Medicine, 2020, Volume: 99, Issue:14

    Topics: Aged; Basal Ganglia; Brain; Carbon Radioisotopes; Cocaine; Female; Fluorine Radioisotopes; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Positron Emission Tomography Computed Tomography; Prospective Studies; Severity of Illness Index

2020
Rate of onset of dopamine transporter inhibitors assessed with intracranial self-stimulation and in vivo dopamine photometry in rats.
    Psychopharmacology, 2023, Volume: 240, Issue:4

    Topics: Animals; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Stimulation

2023