cobaltous chloride has been researched along with heme in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (45.45) | 18.7374 |
| 1990's | 11 (33.33) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cornelius, CE; Freedland, RA; Rodgers, PA | 1 |
| Dutta, GP; Pandey, VC; Sahni, SK; Saxena, N; Tekwani, BL | 1 |
| Abraham, NG; Lin, JH; Martasek, P; Villalon, P | 1 |
| Fujino, S; Hoshi, K; Senda, N | 1 |
| Chhabra, R; Datta, K; Singh, NK | 1 |
| Maines, MD; Rowley, PT; Trakshel, GM | 1 |
| Jayarama Bhat, G; Padmanaban, G | 1 |
| Bhat, GJ; Padmanaban, G | 1 |
| Bhat, GJ; Dwarki, VJ; Francis, VN; Padmanaban, G | 1 |
| Belovetskaia, IV; Kaliman, PA | 1 |
| Klaassen, CD; Stelzer, KJ | 1 |
| Drummond, GS; Kappas, A; Sardana, MK | 1 |
| Padmanaban, G; Ravishankar, H | 2 |
| Kitchin, KT | 1 |
| Hayashi, N; Kikuchi, G | 1 |
| Bonkowsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR; Smith, EL | 1 |
| Immenschuh, S; Iwahara, S; Katz, N; Muller-Eberhard, U; Nell, C; Satoh, H | 1 |
| Awruch, J; Coll, CT; Frydman, RB; Lemberg, A; Mora, ME | 1 |
| Correia, MA; Liu, H | 1 |
| Abraham, NG; Griffin, MO; Kappas, A; Levere, RD; Lutton, JD; Nishimura, M; Shibahara, S | 1 |
| Bonkovsky, HL; Gabis, KK; Gildemeister, OS; Lambrecht, RW; Pepe, JA | 1 |
| Nirodi, CS; Padmanaban, G; Prabhu, L; Ram, N; Sultana, S | 1 |
| Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T | 1 |
| Avadhani, NG; Damle, S; Lenka, N; Vijayasarathy, C | 1 |
| Coutinho, C; O'Brodovich, H; Otulakowski, G; Rafii, B | 1 |
| Abraham, NG; Drummond, GS; Jiang, S; Kappas, A; Laniado-Schwartzman, M; Marji, J; Yang, L; Zand, BA | 1 |
| Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T; Ziemann, C | 1 |
| Fujita, H; Furuyama, K; Hattori, T; Hida, W; Igarashi, K; Kitamuro, T; Nakayama, M; Ogawa, K; Shibahara, S; Shirato, K; Sun, J; Takahashi, K; Takeda, K; Udono-Fujimori, R | 1 |
| Ahmad, M; Chow, JL; Gupte, SA; Mingone, CJ; Wolin, MS | 1 |
| Furuyama, K; Sassa, S; Shibahara, S; Vargas, PD | 1 |
| Chan, P; Chang, CF; Chen, CH; Chen, TH; Lee, HM; Wang, JC; Yu, SC | 1 |
| Sedman, RM; Tephly, TR | 1 |
1 review(s) available for cobaltous chloride and heme
| Article | Year |
|---|---|
Regulation by heme of synthesis and intracellular translocation of delta-aminolevulinate synthase in the liver.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Biological Transport; Cell-Free System; Cobalt; Cytosol; Dicarbethoxydihydrocollidine; Heme; Hemin; Immunodiffusion; Leucine; Liver; Mitochondria, Liver; Molecular Weight; Protoporphyrins; Rabbits; Rats; Tryptophan Oxygenase | 1981 |
32 other study(ies) available for cobaltous chloride and heme
| Article | Year |
|---|---|
Bilirubin production and conjugation from newly formed heme in isolated rat hepatocytes.
Topics: Aminolevulinic Acid; Animals; Bile Pigments; Bilirubin; Cells, Cultured; Cobalt; Heme; Hemin; Kinetics; Liver; Male; Metalloporphyrins; Protoporphyrins; Rats; Rats, Sprague-Dawley | 1992 |
Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice.
Topics: Administration, Oral; Animals; Cell Fractionation; Chloroquine; Cobalt; Heme; Heme Oxygenase (Decyclizing); Injections, Subcutaneous; Liver; Malaria; Mice; Plasmodium yoelii | 1991 |
Regulation of heme oxygenase gene expression by cobalt in rat liver and kidney.
Topics: Animals; Arginine; Cobalt; DNA; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Kidney; Liver; Male; Nucleic Acid Hybridization; Plasmids; Protoporphyrins; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic | 1990 |
Acute effect of amitriptyline, phenobarbital or cobaltous chloride on delta-aminolevulinic acid synthetase, heme oxygenase and microsomal heme content and drug metabolism in rat liver.
Topics: 5-Aminolevulinate Synthetase; Amitriptyline; Animals; Cobalt; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains | 1989 |
Induction of L-alanine:4,5-dioxovalerate transaminase by phenylhydrazine is associated with depletion of heme level.
Topics: Anemia; Animals; Cobalt; Dactinomycin; Erythropoietin; Hematocrit; Heme; Immune Sera; Immunodiffusion; Kidney; Kinetics; Liver; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Transaminases | 1986 |
Regulation of the activity of heme degradative enzymes in K562 erythroleukemic cells: induction by thymidine.
Topics: Bromobenzenes; Cell Line; Cobalt; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Hemin; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Erythroblastic, Acute; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Thymidine | 1987 |
Heme regulates cytochrome P-450 gene transcription elongation.
Topics: Animals; Cell Nucleus; Cobalt; Cytochrome P-450 Enzyme System; Genes; Heme; Kinetics; Methylcholanthrene; Rats; RNA, Messenger; Transcription, Genetic | 1988 |
Heme is a positive regulator of cytochrome P-450 gene transcription.
Topics: Amitrole; Animals; Base Sequence; Cobalt; Cytochrome P-450 Enzyme System; DNA; DNA, Recombinant; Heme; Male; Methylcholanthrene; Molecular Sequence Data; Nucleic Acid Hybridization; Rats; RNA, Messenger; Thioacetamide; Transcription, Genetic | 1988 |
Regulation of cytochrome P-450 messenger RNA and apoprotein levels by heme.
Topics: Allylisopropylacetamide; Amitrole; Animals; Apoproteins; Cobalt; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Heme; Hemin; Male; Phenobarbital; Rats; RNA, Messenger | 1987 |
[Effect of cobalt chloride on the activity of key enzymes of heme metabolism in the rat liver].
Topics: 5-Aminolevulinate Synthetase; Animals; Cobalt; Cycloheximide; Dactinomycin; Enzyme Activation; Heme; Heme Oxygenase (Decyclizing); Kinetics; Liver; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1986 |
Effect of cobalt on biliary excretion of bilirubin and glutathione.
Topics: Animals; Bile; Bilirubin; Chromatography, High Pressure Liquid; Cobalt; Glutathione; Heme; Heme Oxygenase (Decyclizing); Injections, Subcutaneous; Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains | 1985 |
Sn-protoporphyrin rapidly and markedly enhances the heme saturation of hepatic tryptophan pyrrolase. Evidence that this synthetic metalloporphyrin increases the functional content of heme in the liver.
Topics: Animals; Cobalt; Dose-Response Relationship, Drug; Heme; Kinetics; Liver; Male; Metalloporphyrins; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1985 |
Turnover of messenger RNA, apoprotein and haem of cytochrome P-450b + e induced by phenobarbitone in rat liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Apoproteins; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Half-Life; Heme; Liver; Male; Phenobarbital; Rats; RNA, Messenger | 1985 |
Regulation of rat hepatic delta-aminolevulinic acid synthetase and heme oxygenase activities: evidence for control by heme and against mediation by prosthetic iron.
Topics: 5-Aminolevulinate Synthetase; Animals; Bilirubin; Cobalt; Deferoxamine; Dextrans; Edetic Acid; Heme; Heme Oxygenase (Decyclizing); Iron-Dextran Complex; Kinetics; Liver; Male; Mixed Function Oxygenases; Protoporphyrins; Rats | 1983 |
Effect of cobalt chloride and 3-amino-1,2,4-triazole on the induction of cytochrome P-450 synthesis by phenobarbitone in rat liver.
Topics: Amitrole; Animals; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Triazoles | 1983 |
Decrease in hepatic cytochrome P-450 by cobalt. Evidence for a role of cobalt protoporphyrin.
Topics: Animals; Cells, Cultured; Chick Embryo; Cobalt; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Heme; Liver; Male; Microsomes, Liver; Porphyrins; Proteins; Protoporphyrins; Rats; Rats, Inbred Strains | 1982 |
Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxygenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells.
Topics: Animals; Cadmium; Cadmium Chloride; Carrier Proteins; Cell Line; Cells, Cultured; Chlorides; Cobalt; Cytosol; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Heme-Binding Proteins; Hemeproteins; Kinetics; Liver; Liver Neoplasms, Experimental; Mice; Molecular Sequence Data; Rats; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Degradation of heme IX in rats pretreated with cobaltous chloride. A study in isolated perfused liver.
Topics: Animals; Bile; Bilirubin; Cobalt; Glucuronosyltransferase; Heme; In Vitro Techniques; Liver; Male; Molecular Structure; Perfusion; Rats; Rats, Wistar; Reference Values | 1994 |
Cobaltous chloride-mediated induction of rat hepatic tryptophan 2,3-dioxygenase: implications for the use of the enzyme to probe the hepatic free heme pool.
Topics: Adrenal Glands; Adrenalectomy; Animals; Apoenzymes; Cobalt; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Liver; Male; Metals; Rats; Rats, Sprague-Dawley; Tryptophan Oxygenase | 1994 |
Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells.
Topics: Carcinoma, Hepatocellular; Cobalt; Erythropoietin; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Humans; Liver Neoplasms; Metalloporphyrins; Protoporphyrins; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Induction of heme oxygenase-1 in LMH cells. Comparison of LMH cells to primary cultures of chick embryo liver cells.
Topics: Animals; Cells, Cultured; Chick Embryo; Cobalt; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
A 65-kDa protein mediates the positive role of heme in regulating the transcription of CYP2B1/B2 gene in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorides; Cobalt; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ferric Compounds; Gene Expression Regulation, Enzymologic; Heme; Hemin; Liver; Molecular Weight; Nuclear Proteins; Phenobarbital; Protoporphyrins; Rats; RNA, Messenger; Steroid Hydroxylases; Transcription, Genetic | 1997 |
Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.
Topics: Animals; Arteries; Cell Membrane; Chelating Agents; Cobalt; Cytochrome P-450 CYP2B1; Deferoxamine; Enzyme Induction; Enzyme Repression; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Enzymologic; Growth Hormone; Heme; In Vitro Techniques; Liver; Male; Molecular Mimicry; Oxygen; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Thyroxine | 1999 |
Tissue variant effects of heme inhibitors on the mouse cytochrome c oxidase gene expression and catalytic activity of the enzyme complex.
Topics: Adenosine Triphosphate; Animals; Brain; Catalysis; Cobalt; Cyclic AMP-Dependent Protein Kinases; Electron Transport Complex IV; Enzyme Induction; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Heptanoates; Iron; Kidney; Mice; Mitochondria; Mitochondria, Liver; Multienzyme Complexes; Organ Specificity; Porphobilinogen Synthase; RNA, Messenger | 1999 |
Oxygen induction of epithelial Na(+) transport requires heme proteins.
Topics: Amiloride; Animals; Biological Transport; Carrier Proteins; Cobalt; Epithelial Cells; Epithelial Sodium Channels; Fetus; Heme; Hemeproteins; Iron; Iron Chelating Agents; Iron-Binding Proteins; Lung; Metals; Oxygen; Rats; Rats, Wistar; RNA, Messenger; Sodium; Sodium Channels; Transferrin-Binding Proteins | 2000 |
Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity.
Topics: Adenoviridae; Animals; Cobalt; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Gene Transfer Techniques; Genetic Vectors; Heme; Heme Oxygenase (Decyclizing); Humans; Kidney; Liver; Male; Oxygenases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transduction, Genetic | 2000 |
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures.
Topics: Animals; Arteries; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Blotting, Northern; Cells, Cultured; Chelating Agents; Cobalt; Dactinomycin; Deferoxamine; Fluorescent Dyes; Heme; Hepatocytes; Immunoblotting; Male; Nucleic Acid Synthesis Inhibitors; Oxygen; Rats; Rats, Wistar; Rhodamine 123; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Veins | 2000 |
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Blotting, Northern; Blotting, Western; Cattle; Cell Line; Cobalt; Dactinomycin; Deferoxamine; Dimerization; Fanconi Anemia Complementation Group Proteins; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoxia; Interferon-gamma; Leucine Zippers; Luciferases; Membrane Proteins; Models, Genetic; Oxidative Stress; Oxygen; Promoter Regions, Genetic; Rats; RNA, Messenger; Time Factors; Transcription Factors; Transfection; Tumor Cells, Cultured | 2003 |
Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide.
Topics: Acridines; Adrenergic beta-Agonists; Animals; Blotting, Western; Cattle; Cobalt; Enzyme Activation; Enzyme Induction; Guanylate Cyclase; Heme; Heme Oxygenase-1; Isoproterenol; Luminescence; Mesoporphyrins; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Organ Culture Techniques; Protoporphyrins; Pulmonary Artery; Spermine; Superoxides | 2008 |
Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway.
Topics: Blotting, Northern; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cobalt; Deferoxamine; Gene Expression Regulation, Enzymologic; Heme; Humans; Hydroxymethylbilane Synthase; Isoenzymes; Jurkat Cells; K562 Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Tetrapyrroles; Uroporphyrinogen III Synthetase | 2008 |
Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells.
Topics: Animals; Biocatalysis; Carbon Monoxide; Cell Line; Cobalt; Dipyridamole; Enzyme Induction; Epithelial Cells; Gene Expression Regulation; Heme; Heme Oxygenase-1; Kidney Tubules; Mitogen-Activated Protein Kinase Phosphatases; Osteopontin; Rats; Reactive Oxygen Species | 2009 |
Cardiac delta-aminolevulinic acid synthetase activity. Effects of fasting, cobaltous chloride and hemin.
Topics: 5-Aminolevulinate Synthetase; Animals; Cobalt; Fasting; Guinea Pigs; Heart; Heme; Kinetics; Male; Mice; Myocardium; Rabbits; Rats; Rats, Sprague-Dawley | 1980 |