Page last updated: 2024-08-26

cobalt and tungsten carbide

cobalt has been researched along with tungsten carbide in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199013 (18.31)18.7374
1990's22 (30.99)18.2507
2000's17 (23.94)29.6817
2010's18 (25.35)24.3611
2020's1 (1.41)2.80

Authors

AuthorsStudies
Kimula, Y; Kitamura, H; Tozawa, T1
Barberis, M; Fraioli, P; Pietra, R; Rizzato, G; Sabbioni, E1
Abraham, JL; Auchincloss, JH; Gilbert, R; Heitzman, ER; Henneberger, PK; Lax, M; Peppi, DJ1
Hefter, J; Ostreicher, K; Sung, C1
Drew, RT; Firriolo, JM; Kutzman, RS; Shiotsuka, RN1
Lauwerys, R; Lison, D4
Lasfargues, G; Lauwerys, R; Lison, D; Maldague, P1
Demedts, M; van den Eeckhout, AV; Verbeken, E1
Chamberlin, RI; Eisen, EA; Greene, RE; Oliver, LC; Sprince, NL1
Honda, R; Ishizaki, M; Kido, T; Nogawa, K; Tsuritani, I; Yamada, Y; Yamaya, H1
Abraham, JL1
Chamberlin, RI; Hales, CA; Kazemi, H; Sprince, NL; Weber, AL1
Brooks, SM1
Ambe, K; Ikemi, Y; Kitamura, H; Koshi, K; Tozawa, T1
Carbonnelle, P; Fubini, B; Lauwerys, R; Lison, D; Mollo, L1
Abraham, JL; Hunt, A1
Chan-Yeung, M; Kennedy, SM; Lea, J; Marion, S; Teschke, K1
Huaux, F; Lasfargues, G; Lauwerys, R; Lison, D1
Defregger, M; Fend, F; Lechleitner, P; Lhotta, K; Tötsch, M1
Ostreicher, K; Sung, C1
Delos, M; Lardot, C; Lasfargues, G; Lauwerys, R; Lison, D1
Arakawa, M; Hasegawa, T; Kurashige, K; Maruyama, M; Murakami, S; Satoh, M; Suzuki, E; Yokota, T1
Anard, D; Belpaeme, K; Elhajouji, A; Kirsch-Volders, M; Lison, D1
Bozec, C; Deguerry, P; Lasfargues, G; Moulin, JJ; Pellet, F; Peltier, A; Perdrix, A; Romazini, S; Wild, P2
Kirsch-Volders, M; Lison, D; Van Goethem, F1
Demedts, M; Hoet, PH; Nemery, B; Roesems, G1
Antonini, JM; Millecchia, L; Rao, KM; Roberts, JR; Starks, K; Yang, HM1
Buchet, JP; De Boeck, M; Kirsch-Volders, M; Lardau, S; Lison, D1
Eng, P; Lee, HS; Poh, WT; Ren, MQ; Tan, KL; Tang, SM; Watt, F1
Demedts, MG; Hoet, PH; Nemery, B; Roesems, G1
De Backer, S; De Boeck, M; Finsy, R; Kirsch-Volders, M; Lison, D; Lombaert, N1
LUNDGREN, KD; SWENSSON, A1
BROUET, G; COLLET, A; GALLOUEDEC, C; LIOT, F; MARTIN, J; REUET, C; ROUSSEL, G1
ASSOULY, M; BECHTEL, P; BROUET, G; DESOILLE, H; LIOT, F1
SCHEPERS, GW1
Farooq, MU; Klement, U1
Cundari, E; De Boeck, M; Decordier, I; Kirsch-Volders, M; Lison, D; Lombaert, N1
Gejyo, F; Kobayashi, M; Maruyama, M; Moriyama, H; Narita, J; Shimizu, T; Suzuki, E; Takada, T; Terada, M; Watanabe, K1
Kirsch-Volders, M; Lison, D; Lombaert, N; Van Hummelen, P1
BRINTON, HP; FAIRHALL, LT; KEENAN, RG1
Day, GA; Stefaniak, AB; Virji, MA2
Bodoardo, S; Corazzari, I; Fenoglio, I; Francia, C; Fubini, B1
Broding, HC; Drexler, H; Göen, T; Michalke, B1
Busch, W; Gelinsky, M; Kühnel, D; Meissner, T; Potthoff, A; Richter, V; Schirmer, K; Scholz, S; Springer, A1
Bastian, S; Busch, W; Gelinsky, M; Holke, R; Ikonomidou, C; Iwe, M; Kühnel, D; Meissner, T; Pompe, W; Potthoff, A; Richter, V; Schirmer, K; Scholz, S; Springer, A1
Bowman, L; Castranova, V; Ding, M; Fadeel, B; Jiang, B; Kisin, ER; Leonard, S; Lu, Y; Murray, AR; Shvedova, AA; Vallyathan, V; Zhao, J1
Busch, W; Kühnel, D; Schirmer, K; Scholz, S1
Bowman, L; Castranova, V; Ding, M; Shi, X; Zhang, XD; Zhao, J1
Day, GA; Harvey, CJ; Stefaniak, AB; Virji, MA1
Atkins, PR; Foo, KY; Islas-Cital, A; Picó, R1
Busch, W; Kühnel, D; Meißner, T; Potthoff, A; Scheffler, K; Schirmer, K; Springer, A; Wellner, P1
Castrucci, E; Cundari, E; Decordier, I; Kirsch-Volders, M; Lison, D; Lombaert, N; Van Hummelen, P1
Bowman, L; Castranova, V; Ding, M; Leonard, SS; Magaye, R; Zhao, J1
Bowman, L; Ding, M; Hou, L; Meighan, TG; Shi, X1
Barois, N; Chevalier, D; Claude, N; Lorge, E; Moche, H; Nesslany, F1
Moriyama, H; Suzuki, E; Takada, T1
Arena, CB; Armstead, AL; Li, B1
Chevillard, S; Grall, R; Irbah, L; Kortulewski, T; Moche, H; Nesslany, F; Paget, V1
Armstead, AL; Li, B; Minarchick, VC; Nurkiewicz, TR; Porter, DW1
Chevalier, D; Claude, N; Lorge, E; Moche, H; Nesslany, F; Vezin, H1
Ding, M; Fenderson, BA; Jiang, BH; Li, B; Liu, LZ; Yu, JJ; Zheng, JZ; Zhu, Y1
Barrière, T; Gelin, JC; Sahli, M1
Blomberg, E; Hedberg, JF; Hedberg, YS; Isaksson, S; Mei, N; Odnevall Wallinder, I; Wold, S1
Cedervall, T; Ekvall, MT; Hansson, LA; Hedberg, J; Malmendal, A; Odnevall Wallinder, I1

Reviews

3 review(s) available for cobalt and tungsten carbide

ArticleYear
[Pulmonary pathology due to cobalt and hard metals].
    Revue des maladies respiratoires, 1989, Volume: 6, Issue:3

    Topics: Alloys; Cobalt; Humans; Lung Diseases; Occupational Diseases; Tungsten; Tungsten Compounds

1989
Lung disorders resulting from the inhalation of metals.
    Clinics in chest medicine, 1981, Volume: 2, Issue:2

    Topics: Aluminum; Antimony; Barium; Cobalt; Humans; Iron; Lung Diseases; Metals; Metals, Rare Earth; Occupational Diseases; Silver; Tin; Tungsten; Tungsten Compounds; Zirconium

1981
Elemental analysis of occupational and environmental lung diseases by electron probe microanalyzer with wavelength dispersive spectrometer.
    Respiratory investigation, 2014, Volume: 52, Issue:1

    Topics: Cobalt; Dust; Electron Probe Microanalysis; Environmental Exposure; Humans; Lung; Metals; Occupational Diseases; Occupational Exposure; Particle Size; Pneumoconiosis; Tungsten Compounds

2014

Other Studies

68 other study(ies) available for cobalt and tungsten carbide

ArticleYear
Cemented tungsten carbide pneumoconiosis.
    Acta pathologica japonica, 1978, Volume: 28, Issue:6

    Topics: Adult; Bone and Bones; Carbon; Cobalt; Female; Humans; Kidney; Liver; Lung; Metallurgy; Pneumoconiosis; Tungsten; Tungsten Compounds

1978
Multi-element follow up in biological specimens of hard metal pneumoconiosis.
    Sarcoidosis, 1992, Volume: 9, Issue:2

    Topics: Adult; Bronchoalveolar Lavage Fluid; Cobalt; Diagnosis, Differential; Female; Humans; Lung; Male; Metals; Middle Aged; Neutron Activation Analysis; Pneumoconiosis; Sarcoidosis, Pulmonary; Tantalum; Tissue Distribution; Titanium; Tungsten Compounds

1992
Health hazard of poorly regulated exposure during manufacture of cemented tungsten carbides and cobalt.
    British journal of industrial medicine, 1992, Volume: 49, Issue:12

    Topics: Adult; Cobalt; Female; Forced Expiratory Volume; Humans; Lung Diseases; Male; Middle Aged; Occupational Exposure; Pneumoconiosis; Radiography; Residual Volume; Risk Factors; Spirometry; Total Lung Capacity; Tungsten; Tungsten Compounds; Vital Capacity

1992
Improved method for the preparation of TiN-coated WC-Co-based samples for cross-sectional AEM investigation.
    Microscopy research and technique, 1992, Nov-01, Volume: 23, Issue:3

    Topics: Cobalt; Microscopy, Electron; Titanium; Tungsten; Tungsten Compounds

1992
Use of fluidizing bed aerosol generators to establish a dust mixture of two substances at a fixed ratio for inhalation toxicity studies.
    American Industrial Hygiene Association journal, 1992, Volume: 53, Issue:8

    Topics: Aerosols; Air Pollution; Bronchial Provocation Tests; Cobalt; Environmental Monitoring; Humans; Tungsten; Tungsten Compounds

1992
Study of the mechanism responsible for the elective toxicity of tungsten carbide-cobalt powder toward macrophages.
    Toxicology letters, 1992, Volume: 60, Issue:2

    Topics: Animals; Cells, Cultured; Cobalt; Drug Interactions; L-Lactate Dehydrogenase; Macrophages; Mice; Phagocytosis; Solubility; Tungsten; Tungsten Compounds

1992
Biological responses of isolated macrophages to cobalt metal and tungsten carbide-cobalt powders.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:4

    Topics: Animals; Cells, Cultured; Cobalt; Glucose; Guanosine Diphosphate; Macrophages; Macrophages, Alveolar; Peritoneal Cavity; Plasminogen Activators; Powders; Rats; Rats, Inbred Strains; Superoxides; Tungsten; Tungsten Compounds

1991
Comparative study of the acute lung toxicity of pure cobalt powder and cobalt-tungsten carbide mixture in rat.
    Toxicology and applied pharmacology, 1992, Volume: 112, Issue:1

    Topics: Animals; Biological Availability; Bronchoalveolar Lavage Fluid; Cobalt; Dust; Female; Lung; Lung Diseases; Organ Size; Rats; Rats, Inbred Strains; Time Factors; Trachea; Tungsten; Tungsten Compounds

1992
In vitro cytotoxic effects of cobalt-containing dusts on mouse peritoneal and rat alveolar macrophages.
    Environmental research, 1990, Volume: 52, Issue:2

    Topics: Animals; Biological Availability; Cells, Cultured; Cobalt; Cytoplasm; Dust; Female; L-Lactate Dehydrogenase; Macrophages; Male; Mice; Peritoneal Cavity; Pulmonary Alveoli; Rats; Silicon Dioxide; Tungsten; Tungsten Compounds

1990
Cobalt exposure and lung disease in tungsten carbide production. A cross-sectional study of current workers.
    The American review of respiratory disease, 1988, Volume: 138, Issue:5

    Topics: Carbon Monoxide; Cobalt; Cross-Sectional Studies; Forced Expiratory Volume; Humans; Lung Diseases; Metallurgy; Occupational Diseases; Pulmonary Diffusing Capacity; Radiography, Thoracic; Respiratory Sounds; Tungsten; Tungsten Compounds; Vital Capacity

1988
Analysis of dusts and evaluation of dust exposure in a hard metal factory.
    Industrial health, 1987, Volume: 25, Issue:1

    Topics: Air Pollutants, Occupational; Cobalt; Dust; Environmental Exposure; Humans; Spectrophotometry, Atomic; Tungsten; Tungsten Compounds; X-Ray Diffraction

1987
Exposure to hard metal.
    Chest, 1985, Volume: 87, Issue:4

    Topics: Cobalt; Humans; Pulmonary Fibrosis; Tungsten; Tungsten Compounds

1985
Respiratory disease in tungsten carbide production workers.
    Chest, 1984, Volume: 86, Issue:4

    Topics: Adult; Air Pollutants; Carbon Dioxide; Cobalt; Dust; Female; Humans; Lung; Lung Diseases, Obstructive; Male; Middle Aged; Oxygen; Pneumoconiosis; Pulmonary Fibrosis; Respiratory Function Tests; Smoking; Tungsten; Tungsten Compounds

1984
[Experimental pneumoconiosis induced by cemented tungsten and sequential concentrations of cobalt and tungsten in the lungs of the rat (author's transl)].
    Sangyo igaku. Japanese journal of industrial health, 1981, Volume: 23, Issue:3

    Topics: Animals; Cobalt; Lung; Pneumoconiosis; Rats; Sternum; Tungsten; Tungsten Compounds

1981
Physicochemical mechanism of the interaction between cobalt metal and carbide particles to generate toxic activated oxygen species.
    Chemical research in toxicology, 1995, Volume: 8, Issue:4

    Topics: Animals; Arachidonic Acid; Cell Survival; Chemical Phenomena; Chemistry, Physical; Cobalt; Electrochemistry; Electron Spin Resonance Spectroscopy; In Vitro Techniques; L-Lactate Dehydrogenase; Macrophages; Mice; Particle Size; Peroxides; Reactive Oxygen Species; Solubility; Thiobarbituric Acid Reactive Substances; Tungsten Compounds

1995
Environmental contamination by cobalt in the vicinity of a cemented tungsten carbide tool grinding plant.
    Environmental research, 1995, Volume: 69, Issue:1

    Topics: Air Pollutants, Occupational; Cobalt; Dust; Industrial Waste; Metallurgy; Microscopy, Electron; Soil Pollutants; Tungsten Compounds

1995
Maintenance of stellite and tungsten carbide saw tips: respiratory health and exposure-response evaluations.
    Occupational and environmental medicine, 1995, Volume: 52, Issue:3

    Topics: Adult; Chromium; Chromium Alloys; Cobalt; Cross-Sectional Studies; Dust; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Pilot Projects; Respiration Disorders; Tungsten Compounds; Vital Capacity

1995
Lung toxicity of hard metal particles and production of interleukin-1, tumor necrosis factor-alpha, fibronectin, and cystatin-c by lung phagocytes.
    Toxicology and applied pharmacology, 1995, Volume: 132, Issue:1

    Topics: Alloys; Animals; Bronchoalveolar Lavage Fluid; Cobalt; Cystatin C; Cystatins; Female; Fibronectins; Interleukin-1; Intubation, Intratracheal; Lung; Phagocytes; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Tumor Necrosis Factor-alpha; Tungsten Compounds

1995
Evaluation of the role of reactive oxygen species in the interactive toxicity of carbide-cobalt mixtures on macrophages in culture.
    Archives of toxicology, 1993, Volume: 67, Issue:5

    Topics: Animals; Cells, Cultured; Cobalt; Deoxyribose; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Indicators and Reagents; Iron; Macrophages; Mice; Reactive Oxygen Species; Tungsten; Tungsten Compounds

1993
Goodpasture's syndrome. Unusual presentation after exposure to hard metal dust.
    Chest, 1993, Volume: 103, Issue:3

    Topics: Adult; Alloys; Anti-Glomerular Basement Membrane Disease; Biopsy; Cobalt; Dust; Humans; Kidney; Male; Occupational Diseases; Tungsten; Tungsten Compounds

1993
Cross-sectional AEM preparation technique for ceramic-coated WC-Co cutting tools.
    Microscopy research and technique, 1993, Apr-15, Volume: 24, Issue:6

    Topics: Ceramics; Cobalt; Epoxy Compounds; Microscopy, Electron; Nickel; Stress, Mechanical; Titanium; Tungsten; Tungsten Compounds

1993
The delayed lung responses to single and repeated intratracheal administration of pure cobalt and hard metal powder in the rat.
    Environmental research, 1995, Volume: 69, Issue:2

    Topics: Acetylglucosaminidase; Albumins; Animals; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Bronchoalveolar Lavage Fluid; Cobalt; Disease Models, Animal; Female; Fibronectins; Hyaluronic Acid; L-Lactate Dehydrogenase; Lung; Oxides; Powders; Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Staining and Labeling; Trachea; Tungsten Compounds

1995
[Hard metal lung with diffuse small nodular shadows].
    Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34, Issue:4

    Topics: Adult; Cobalt; Female; Humans; Lung; Lung Diseases, Interstitial; Pneumoconiosis; Radiography, Thoracic; Tomography, X-Ray Computed; Tungsten Compounds

1996
In vitro genotoxic effects of hard metal particles assessed by alkaline single cell gel and elution assays.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: Cobalt; DNA; DNA Damage; Dose-Response Relationship, Drug; Humans; Mutagenicity Tests; Tungsten Compounds

1997
[Development of a job-exposure matrix in the heavy-metal industry in France].
    Revue d'epidemiologie et de sante publique, 1997, Volume: 45, Issue:1

    Topics: Case-Control Studies; Cobalt; Cohort Studies; Delphi Technique; France; Humans; Lung Neoplasms; Metallurgy; Occupational Exposure; Risk Assessment; Tungsten Compounds

1997
Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide.
    Mutation research, 1997, Aug-01, Volume: 392, Issue:1-2

    Topics: Adult; Alloys; Cells, Cultured; Cobalt; Electrophoresis, Agar Gel; Evaluation Studies as Topic; Humans; Lymphocytes; Micronucleus Tests; Mutagens; Tungsten; Tungsten Compounds

1997
In vitro toxicity of cobalt and hard metal dust in rat and human type II pneumocytes.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:2

    Topics: Animals; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Dust; Epithelial Cells; Humans; L-Lactate Dehydrogenase; Macrophages, Alveolar; Male; Pulmonary Alveoli; Rats; Rats, Wistar; Species Specificity; Tungsten Compounds

1997
Lung cancer risk in hard-metal workers.
    American journal of epidemiology, 1998, Aug-01, Volume: 148, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Air Pollutants, Occupational; Case-Control Studies; Cobalt; Cohort Studies; Female; Follow-Up Studies; France; Humans; Lung Neoplasms; Male; Metallurgy; Middle Aged; Occupational Diseases; Occupational Exposure; Retrospective Studies; Risk Factors; Tungsten Compounds

1998
Changes in F-actin organization induced by hard metal particle exposure in rat pulmonary epithelial cells using laser scanning confocal microscopy.
    In vitro & molecular toxicology, 2000,Spring, Volume: 13, Issue:1

    Topics: Actin Cytoskeleton; Actins; Alloys; Animals; Cell Line; Cell Survival; Cobalt; Cytoskeleton; Dose-Response Relationship, Drug; Epithelial Cells; Fluorescent Dyes; Inhalation Exposure; L-Lactate Dehydrogenase; Lung; Metals, Heavy; Microscopy, Confocal; Microscopy, Phase-Contrast; Pulmonary Fibrosis; Rats; Tungsten Compounds

2000
Absence of significant genotoxicity in lymphocytes and urine from workers exposed to moderate levels of cobalt-containing dust: a cross-sectional study.
    Environmental and molecular mutagenesis, 2000, Volume: 36, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Air Pollutants, Occupational; Cobalt; Comet Assay; Cross-Sectional Studies; Deoxyguanosine; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Dust; Humans; Lymphocytes; Male; Micronucleus Tests; Middle Aged; N-Glycosyl Hydrolases; Occupational Exposure; Reproducibility of Results; Selenium; Tungsten Compounds; Urine; Vitamin E

2000
Hard metal lung disease--the first case in Singapore.
    Annals of the Academy of Medicine, Singapore, 2000, Volume: 29, Issue:4

    Topics: Adult; Air Pollutants, Occupational; Biopsy; Cobalt; Environmental Monitoring; Humans; Male; Medical History Taking; Occupational Diseases; Pneumoconiosis; Pulmonary Fibrosis; Respiratory Function Tests; Singapore; Spectrometry, X-Ray Emission; Titanium; Tomography, X-Ray Computed; Tuberculosis, Pulmonary; Tungsten Compounds

2000
Activation of the hexose monophosphate shunt in rat type II pneumocytes as an early marker of oxidative stress caused by cobalt particles.
    Archives of toxicology, 2002, Volume: 76, Issue:1

    Topics: Animals; Biomarkers; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Drug Combinations; Dust; Hydrogen Peroxide; Male; Oxidative Stress; Particle Size; Pentose Phosphate Pathway; Pulmonary Alveoli; Rats; Rats, Wistar; tert-Butylhydroperoxide; Tungsten Compounds

2002
In vitro genotoxic effects of different combinations of cobalt and metallic carbide particles.
    Mutagenesis, 2003, Volume: 18, Issue:2

    Topics: Adult; Carbon; Cell Division; Cells, Cultured; Chromium; Cobalt; Comet Assay; DNA; DNA Damage; Female; Humans; Leukocytes, Mononuclear; Linear Models; Male; Metals; Micronucleus Tests; Mutagenicity Tests; Niobium; Reactive Oxygen Species; Risk; Time Factors; Tungsten Compounds

2003
Experimental investigations using the method of Miller and Sayers on the effect upon animals of cemented tungsten carbides, and the powders used as raw material.
    Acta medica Scandinavica, 1953, Volume: 145, Issue:1

    Topics: Animals; Cobalt; Powders; Titanium; Tungsten; Tungsten Compounds

1953
[Electron microscope study of various cellular aspects of a pulmonary fibroadenomatosis with diffusion disorder. (Discussion of the etiological role of cobalt and tungsten carbide)].
    Revue de tuberculose et de pneumologie, 1963, Volume: 27

    Topics: Adenofibroma; Cobalt; Electrons; Fibroma; Lung Neoplasms; Microscopy, Electron; Respiratory Insufficiency; Tungsten; Tungsten Compounds

1963
[Diffuse pulmonary fibrosis in a subject exposed to cobalt and tungsten carbide dusts (heavy metal industry). Discussion of a simple coincidence or an ultimate relation of cause and effect].
    Archives des maladies professionnelles de medecine du travail et de securite sociale, 1962, Volume: 23

    Topics: Cobalt; Dust; Humans; Metallurgy; Pulmonary Fibrosis; Tungsten Compounds

1962
The biological action of tungsten carbide and cobalt; studies on experimental pulmonary histopathology.
    A.M.A. archives of industrial health, 1955, Volume: 12, Issue:2

    Topics: Cobalt; Humans; Lung; Lung Diseases; Tungsten; Tungsten Compounds

1955
EBSD characterization of carbide-carbide boundaries in WC-Co composites.
    Journal of microscopy, 2004, Volume: 213, Issue:3

    Topics: Cobalt; Microscopy, Electron; Tungsten Compounds

2004
Evaluation of the apoptogenic potential of hard metal dust (WC-Co), tungsten carbide and metallic cobalt.
    Toxicology letters, 2004, Dec-01, Volume: 154, Issue:1-2

    Topics: Annexin A5; Apoptosis; Caspases; Cells, Cultured; Cobalt; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Leukocytes, Mononuclear; Microscopy, Electron; Monocytes; Tungsten Compounds

2004
Two-dimensional analysis of elements and mononuclear cells in hard metal lung disease.
    American journal of respiratory and critical care medicine, 2007, Jul-01, Volume: 176, Issue:1

    Topics: Adult; Alloys; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biopsy; Case-Control Studies; CD8-Positive T-Lymphocytes; Cobalt; Cohort Studies; Female; Giant Cells, Foreign-Body; Humans; Immunohistochemistry; Lung Diseases, Interstitial; Macrophages, Alveolar; Male; Middle Aged; Occupational Exposure; Phagocytosis; Receptors, Cell Surface; T-Lymphocytes, Cytotoxic; Tungsten; Tungsten Compounds

2007
In vitro expression of hard metal dust (WC-Co)--responsive genes in human peripheral blood mononucleated cells.
    Toxicology and applied pharmacology, 2008, Mar-01, Volume: 227, Issue:2

    Topics: Carcinogens; Cobalt; Down-Regulation; Dust; Gene Expression; Humans; Lymphocytes; Monocytes; Oligonucleotide Array Sequence Analysis; Particle Size; Reverse Transcriptase Polymerase Chain Reaction; Tungsten Compounds; Up-Regulation

2008
Cobalt and the dust environment of the cemented tungsten carbide industry.
    Public health reports (Washington, D.C. : 1896), 1949, Apr-15, Volume: 64, Issue:15

    Topics: Cobalt; Dust; Humans; Hygiene; Industry; Occupational Diseases; Occupations; Tungsten Compounds

1949
Characterization of exposures among cemented tungsten carbide workers. Part II: Assessment of surface contamination and skin exposures to cobalt, chromium and nickel.
    Journal of exposure science & environmental epidemiology, 2009, Volume: 19, Issue:4

    Topics: Chromium; Cobalt; Nickel; Occupational Exposure; Tungsten Compounds

2009
Characterization of exposures among cemented tungsten carbide workers. Part I: Size-fractionated exposures to airborne cobalt and tungsten particles.
    Journal of exposure science & environmental epidemiology, 2009, Volume: 19, Issue:5

    Topics: Cobalt; Humans; Occupational Exposure; Particle Size; Quality Control; Tungsten Compounds

2009
The oxidation of glutathione by cobalt/tungsten carbide contributes to hard metal-induced oxidative stress.
    Free radical research, 2008, Volume: 42, Issue:8

    Topics: Cobalt; Electrochemistry; Electron Spin Resonance Spectroscopy; Glutathione; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Superoxides; Trace Elements; Tungsten Compounds; Xanthine; Xanthine Oxidase

2008
Comparison between exhaled breath condensate analysis as a marker for cobalt and tungsten exposure and biomonitoring in workers of a hard metal alloy processing plant.
    International archives of occupational and environmental health, 2009, Volume: 82, Issue:5

    Topics: Adult; Air; Alloys; Biomarkers; Breath Tests; Cobalt; Environmental Monitoring; Exhalation; Female; Humans; Male; Metallurgy; Middle Aged; Occupational Exposure; Tungsten Compounds; Young Adult

2009
Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line.
    Aquatic toxicology (Amsterdam, Netherlands), 2009, Jun-28, Volume: 93, Issue:2-3

    Topics: Animals; Cell Line; Cell Survival; Cobalt; Culture Media; Environmental Exposure; Gills; Metal Nanoparticles; Oncorhynchus mykiss; Tungsten Compounds

2009
Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro.
    Environmental health perspectives, 2009, Volume: 117, Issue:4

    Topics: Animals; Caco-2 Cells; Cell Line; Cell Survival; Cobalt; Epithelial Cells; Humans; Keratinocytes; Metal Nanoparticles; Oligodendroglia; Rats; Rats, Wistar; Tungsten Compounds

2009
Size-dependent effects of tungsten carbide-cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells.
    Toxicology and applied pharmacology, 2009, Dec-15, Volume: 241, Issue:3

    Topics: Animals; Cell Line; Cell Proliferation; Cobalt; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epidermal Cells; Epidermis; Glutathione; Immunohistochemistry; Indicators and Reagents; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinases; Nanoparticles; NF-kappa B; Particle Size; Reactive Oxygen Species; Signal Transduction; Sulfhydryl Compounds; Transcription Factor AP-1; Tungsten Compounds

2009
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes.
    BMC genomics, 2010, Jan-27, Volume: 11

    Topics: Carbohydrate Metabolism; Cell Hypoxia; Cell Line; Cluster Analysis; Cobalt; Gene Expression Profiling; Humans; Hypoxia-Inducible Factor 1; Keratinocytes; Nanoparticles; Oligonucleotide Array Sequence Analysis; Principal Component Analysis; Signal Transduction; Tungsten Compounds

2010
Tungsten carbide-cobalt particles activate Nrf2 and its downstream target genes in JB6 cells possibly by ROS generation.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2010, Volume: 29, Issue:1

    Topics: Animals; Blotting, Western; Cell Line; Cell Nucleus; Cobalt; Epidermis; Glutathione Transferase; Metal Nanoparticles; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Reactive Oxygen Species; Tungsten Compounds

2010
Dissolution of cemented carbide powders in artificial sweat: implications for cobalt sensitization and contact dermatitis.
    Journal of environmental monitoring : JEM, 2010, Oct-06, Volume: 12, Issue:10

    Topics: Cobalt; Dermatitis, Contact; Environmental Exposure; Humans; Hydrogen-Ion Concentration; Kinetics; Particle Size; Risk Factors; Sweat; Tungsten; Tungsten Compounds; Vitamin E

2010
Final report on carcinogens background document for cobalt-tungsten carbide: powders and hard metals.
    Report on carcinogens background document for [substance name], 2009, Issue:9-5979

    Topics: Alloys; Animals; Carcinogens; Cobalt; Humans; Occupational Exposure; Powders; Research Report; Tungsten; Tungsten Compounds

2009
Cobalt-tungsten carbide: powders and hard metals.
    Report on carcinogens : carcinogen profiles, 2011, Volume: 12

    Topics: Alloys; Animals; Carcinogens; Cobalt; Humans; Neoplasms; Powders; Tungsten; Tungsten Compounds

2011
Phase calibration of sonar systems using standard targets and dual-frequency transmission pulses.
    The Journal of the Acoustical Society of America, 2011, Volume: 130, Issue:4

    Topics: Calibration; Cobalt; Equipment Design; Models, Theoretical; Motion; Signal Processing, Computer-Assisted; Sound; Time Factors; Transducers; Tungsten Compounds; Ultrasonics; Vibration

2011
Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro.
    Journal of hazardous materials, 2012, Aug-15, Volume: 227-228

    Topics: Cell Line; Cell Survival; Cobalt; Humans; Metal Nanoparticles; Micronucleus Tests; Reactive Oxygen Species; Surface Properties; Tungsten Compounds

2012
Hard-metal (WC-Co) particles trigger a signaling cascade involving p38 MAPK, HIF-1α, HMOX1, and p53 activation in human PBMC.
    Archives of toxicology, 2013, Volume: 87, Issue:2

    Topics: Cobalt; Dust; Gene Expression; Gene Expression Profiling; Heme Oxygenase-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhalation Exposure; Leukocytes, Mononuclear; Occupational Exposure; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Particulate Matter; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tumor Suppressor Protein p53; Tungsten Compounds

2013
Apoptosis induced by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS generation through both extrinsic and intrinsic apoptosis pathways.
    International journal of oncology, 2013, Volume: 42, Issue:4

    Topics: Air Pollutants, Occupational; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; Carcinogens; Caspases; Cell Line; Cell Survival; Cobalt; Cytochromes c; fas Receptor; Lung; Macrophages; Mice; Mitochondrial Membranes; Particle Size; Permeability; Rats; Reactive Oxygen Species; Surface Properties; Tungsten Compounds

2013
Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2013, Volume: 32, Issue:1

    Topics: Animals; Apoptosis Regulatory Proteins; Butadienes; Cell Line; Cell Transformation, Neoplastic; Cobalt; Disease Models, Animal; Enzyme Inhibitors; Epidermis; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; MAP Kinase Signaling System; Mice; MicroRNAs; Mitogen-Activated Protein Kinase Kinases; Nanoparticles; Nitriles; Occupational Exposure; Pyridines; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Tungsten Compounds

2013
Tungsten carbide-cobalt as a nanoparticulate reference positive control in in vitro genotoxicity assays.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 137, Issue:1

    Topics: Adult; Animals; Cell Line, Tumor; Cobalt; Comet Assay; Dose-Response Relationship, Drug; Female; Humans; Lymphocytes; Lymphoma; Male; Metal Nanoparticles; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Reference Standards; Tungsten Compounds

2014
Exploring the potential role of tungsten carbide cobalt (WC-Co) nanoparticle internalization in observed toxicity toward lung epithelial cells in vitro.
    Toxicology and applied pharmacology, 2014, Jul-01, Volume: 278, Issue:1

    Topics: Apoptosis; Cell Survival; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Endocytosis; Epithelial Cells; Humans; Inhalation Exposure; Lung; Metal Nanoparticles; Occupational Exposure; Oxidative Stress; Particle Size; Time Factors; Tungsten Compounds

2014
Human cell line-dependent WC-Co nanoparticle cytotoxicity and genotoxicity: a key role of ROS production.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 143, Issue:2

    Topics: Cell Cycle Checkpoints; Cell Line; Cell Survival; Cobalt; DNA Damage; Flow Cytometry; Humans; Kidney; Liver; Microscopy, Confocal; Nanoparticles; Organ Specificity; Reactive Oxygen Species; Tungsten Compounds

2015
Acute inflammatory responses of nanoparticles in an intra-tracheal instillation rat model.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Bronchoalveolar Lavage; Cobalt; Inflammation; Interleukin-6; Male; Nanoparticles; Pneumonia; Rats; Rats, Sprague-Dawley; Toxicity Tests, Acute; Trachea; Tumor Necrosis Factor-alpha; Tungsten Compounds

2015
Genotoxicity of tungsten carbide-cobalt (WC-Co) nanoparticles in vitro: mechanisms-of-action studies.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 779

    Topics: Aneugens; Animals; Cell Line, Tumor; Chromosome Aberrations; Cobalt; Comet Assay; DNA Damage; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Mice; Micronucleus Tests; Mutagens; Nanoparticles; Reactive Oxygen Species; Tungsten Compounds

2015
Tungsten Carbide-Cobalt Nanoparticles Induce Reactive Oxygen Species, AKT, ERK, AP-1, NF-κB, VEGF, and Angiogenesis.
    Biological trace element research, 2015, Volume: 166, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Cell Line, Tumor; Chickens; Chorioallantoic Membrane; Cobalt; Epithelial Cells; Humans; Luciferases; MAP Kinase Signaling System; Nanoparticles; NF-kappa B; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tungsten Compounds; Vascular Endothelial Growth Factor A

2015
Replication of microchannel structures in WC-Co feedstock using elastomeric replica moulds by hot embossing process.
    Materials science & engineering. C, Materials for biological applications, 2015, Volume: 55

    Topics: Alloys; Cobalt; Elastomers; Lab-On-A-Chip Devices; Metallurgy; Polymers; Temperature; Tungsten Compounds

2015
Nanoparticles of WC-Co, WC, Co and Cu of relevance for traffic wear particles - Particle stability and reactivity in synthetic surface water and influence of humic matter.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 224

    Topics: Automobiles; Cobalt; Copper; Humic Substances; Nanoparticles; Particle Size; Rubber; Tungsten Compounds; Water

2017
Adsorption of bio-organic eco-corona molecules reduces the toxic response to metallic nanoparticles in Daphnia magna.
    Scientific reports, 2021, 05-24, Volume: 11, Issue:1

    Topics: Adsorption; Animals; Biodegradation, Environmental; Cobalt; Daphnia; Ecosystem; Metal Nanoparticles; Particle Size; Surface Properties; Tungsten Compounds; Water Pollutants, Chemical

2021