Page last updated: 2024-08-26

cobalt and sirolimus

cobalt has been researched along with sirolimus in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (24.00)29.6817
2010's16 (64.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Giorgetti-Peraldi, S; Murdaca, J; Semenza, GL; Treins, C; Van Obberghen, E1
Abraham, RT; Chiang, GG; Giaccia, AJ; Hudson, CC; Kaper, F; Liu, M; Loomis, DC; Otterness, DM1
Arnold, W; Giese, K; Kaufmann, J; Klippel, A; Schwarzer, R; Tondera, D1
Rosenzweig, SA; Slomiany, MG1
Chen, JL; Gao, RL; Hong, T; Hu, J; Huo, Y; Li, JP; Qiao, SB; Qin, XW; Shen, WF; Xu, B; Yang, YJ; Zhang, JS; Zhang, Q; Zhang, RY1
Ako, J; Fitzgerald, PJ; Hasegawa, T; Honda, Y; Kandzari, DE; Leon, MB; Miyazawa, A; Sakurai, R; Tsujino, I; Waseda, K; Yock, PG1
Ge, J; Ge, L; Qian, J; Zhang, F; Zhou, J1
Domb, AJ; Farah, S; Khan, W1
Brugaletta, S; Cequier, A; de Belder, A; de la Torre Hernandez, JM; Eberli, F; Ferrante, G; Galatius, S; Kaiser, C; Sabaté, M; Serruys, PW; Valgimigli, M1
Li, D; Liu, F; Qi, L; Wang, M; Yan, G; Yang, T1
Hu, ZY; Iqbal, J; Pan, DR; Pang, S; Tian, NL; Wu, W; Xu, B; Zhang, YJ; Zhu, H1
Ahn, DJ; Han, DK; Joung, YK; Jung, JW; Lih, E1
Ge, J; Ge, L; Qian, J; Yang, J; Zhang, F; Zhou, J1
Chen, C; Chung, SM; Kong, X; Lee, IS; Luo, D; Yang, J; Yao, C1
Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST1
Asano, T; de Winter, RJ; Dijkstra, J; Jonker, H; Katagiri, Y; Kimura, T; Kozuma, K; Miyazaki, Y; Onuma, Y; Popma, JJ; Serruys, PW; Sotomi, Y; Stone, GW; Tanabe, K; Tenekecioglu, E; Wykrzykowska, JJ1
Bil, J; Gil, RJ; Kern, A; Pawłowski, T1
Anderson, R; Asano, T; Baumbach, A; Johnson, T; Kiemeneij, F; Lansky, AJ; Onuma, Y; Serruys, PW; Slagboom, T; Van Royen, N; Vlachojannis, G; Wijns, W; Xu, B; Zheng, M1
Bedair, TM; Han, DK; Joung, YK; Min, IJ; Park, W1
Chen, D; Chen, Z; Dai, C; Han, Z; He, F; Li, Y; Tan, R; Tian, H; Wang, G; Wang, M; Wei, L; Yang, B; Yang, H; Zhang, B1
Bil, J; Gąsior, M; Gil, RJ; Kern, A; Legutko, J; Lesiak, M; Pawłowski, T; Witkowski, A1
Aoki, J; Awata, M; Kashiwabara, K; Kimura, T; Kozuma, K; Matsuyama, Y; Nanasato, M; Oba, K; Shinozaki, T; Shiode, N; Tanabe, K; Yamaguchi, J1
Asano, T; Chichareon, P; Digne, F; Gil, RJ; Kogame, N; Lefèvre, T; Legutko, J; Modolo, R; Morel, MA; Onuma, Y; Serruys, PW1
Pavithran, S; Rajendran, M; Ramasamy, R; Sivakumar, K; Sonawane, B1
Choi, YJ; Kang, JM; Kang, WS; Kim, SH; Park, HJ; Park, JH; Park, Y; Ryu, DS1

Reviews

2 review(s) available for cobalt and sirolimus

ArticleYear
Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis.
    BMJ (Clinical research ed.), 2014, Nov-04, Volume: 349

    Topics: Chromium; Cobalt; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Humans; Myocardial Infarction; Sirolimus; Stents; Thrombosis; Treatment Outcome

2014
Cobalt chromium-based biodegradable polymer sirolimus-eluting stent: rationale, evidence and clinical experience.
    Minerva cardioangiologica, 2015, Volume: 63, Issue:5

    Topics: Chromium; Cobalt; Coronary Artery Disease; Drug Liberation; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Polymers; Prosthesis Design; Sirolimus; Thrombosis

2015

Trials

5 trial(s) available for cobalt and sirolimus

ArticleYear
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:8

    Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible; Cobalt; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Hyperplasia; Male; Middle Aged; Paclitaxel; Phosphorylcholine; Prosthesis Design; Single-Blind Method; Sirolimus; Time Factors; Treatment Outcome; Tunica Intima; Ultrasonography, Interventional; United States

2009
Two-year clinical outcomes of patients with the second-generation cobalt-chromium sirolimus-eluting stents from the real-world FOCUS registry.
    International journal of cardiology, 2013, Jul-01, Volume: 166, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Chromium; Cobalt; Cohort Studies; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Registries; Sirolimus; Time Factors; Treatment Outcome

2013
Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018, Nov-20, Volume: 14, Issue:10

    Topics: Atherosclerosis; Chromium; Cobalt; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Europe; Humans; Neointima; Prospective Studies; Prosthesis Design; Sirolimus; Stents; Tomography, Optical Coherence; Treatment Outcome

2018
Rationale and design of the randomized, multicenter, open-label, controlled POLBOS 3 trial aimed to compare regular drug-eluting stents versus the dedicated coronary bifurcation sirolimus-eluting BiOSS LIM C stent.
    Medicine, 2019, Volume: 98, Issue:14

    Topics: Acute Coronary Syndrome; Chromium; Cobalt; Coronary Stenosis; Drug-Eluting Stents; Humans; Multicenter Studies as Topic; Percutaneous Coronary Intervention; Randomized Controlled Trials as Topic; Research Design; Self Expandable Metallic Stents; Sirolimus; Treatment Outcome

2019
Treatment with a dedicated bifurcation sirolimus-eluting cobalt-chromium stent for distal left main coronary artery disease: rationale and design of the POLBOS LM study.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2020, Oct-23, Volume: 16, Issue:8

    Topics: Chromium; Cobalt; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Prospective Studies; Prosthesis Design; Sirolimus; Stents; Treatment Outcome

2020

Other Studies

18 other study(ies) available for cobalt and sirolimus

ArticleYear
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    The Journal of biological chemistry, 2002, Aug-02, Volume: 277, Issue:31

    Topics: Animals; Cell Line; Cell Nucleus; Cobalt; DNA-Binding Proteins; Endothelial Growth Factors; Gene Expression Regulation; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Kinetics; Lymphokines; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Pigment Epithelium of Eye; Plasmids; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Transcription Factors; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
    Molecular and cellular biology, 2002, Volume: 22, Issue:20

    Topics: Cell Hypoxia; Chromones; Cobalt; DNA-Binding Proteins; Enzyme Inhibitors; Glucose Transporter Type 1; Helix-Loop-Helix Motifs; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Monosaccharide Transport Proteins; Morpholines; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; TOR Serine-Threonine Kinases; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

2002
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
    Oncogene, 2005, Feb-10, Volume: 24, Issue:7

    Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Chromones; Cobalt; Dimethyl Sulfoxide; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; RNA, Antisense; Signal Transduction; Sirolimus; Transcription Factors; Up-Regulation

2005
Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Anti-Bacterial Agents; Cell Line; Cobalt; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Immunoblotting; Immunohistochemistry; Insulin-Like Growth Factor I; Ligands; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sirolimus; Stimulation, Chemical; Transfection; Vascular Endothelial Growth Factor A

2006
Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease: six-month angiographic and one-year clinical follow-up result. A prospective, historically controlled, multi-center clinical study.
    Chinese medical journal, 2007, Apr-05, Volume: 120, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Cobalt; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Coronary Vessels; Drug Delivery Systems; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Sirolimus; Stents; Ultrasonography, Interventional

2007
Crystalline coating of rapamycin onto a stent: process development and characterization.
    International journal of pharmaceutics, 2013, Mar-10, Volume: 445, Issue:1-2

    Topics: Chromium; Cobalt; Crystallization; Drug-Eluting Stents; Microscopy, Atomic Force; Powder Diffraction; Sirolimus; Surface Properties; X-Ray Diffraction

2013
Regulation on Beclin-1 expression by mTOR in CoCl2-induced HT22 cell ischemia-reperfusion injury.
    Brain research, 2015, Jul-21, Volume: 1614

    Topics: Analysis of Variance; Animals; Antimutagenic Agents; Apoptosis Regulatory Proteins; Beclin-1; Brain Ischemia; Cell Line; Cell Survival; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Mice; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus

2015
Synergistic effect of anti-platelet and anti-inflammation of drug-coated Co-Cr substrates for prevention of initial in-stent restenosis.
    Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140

    Topics: Anti-Inflammatory Agents; Aspirin; Cells, Cultured; Chromium Alloys; Cobalt; Coronary Restenosis; Drug Liberation; Drug Synergism; Drug-Eluting Stents; Humans; Microscopy, Electron, Scanning; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Polyesters; Prasugrel Hydrochloride; Propolis; Sirolimus

2016
Comparison of long-term clinical outcomes after the second-generation cobalt-chromium sirolimus-eluting stents implantation in diabetic versus non-diabetic patients: a subgroup analysis from the prospective FOCUS registry.
    Annals of medicine, 2016, Volume: 48, Issue:3

    Topics: Aged; Chromium; Cobalt; Coronary Artery Disease; Diabetes Mellitus; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Prospective Studies; Sirolimus; Treatment Outcome

2016
Biomimetic apatite formed on cobalt-chromium alloy: A polymer-free carrier for drug eluting stent.
    Colloids and surfaces. B, Biointerfaces, 2017, Mar-01, Volume: 151

    Topics: Apatites; Arteries; Biomimetic Materials; Cell Adhesion; Cell Proliferation; Chromium Alloys; Cobalt; Coronary Restenosis; Drug Delivery Systems; Drug-Eluting Stents; Humans; Myocytes, Smooth Muscle; Polymers; Porosity; Sirolimus; Surface Properties; X-Ray Diffraction

2017
Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway.
    International journal of oncology, 2017, Volume: 50, Issue:3

    Topics: Adenine; Antimutagenic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Cobalt; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Microtubule-Associated Proteins; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Sirolimus; Tumor Suppressor Protein p53

2017
Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus-eluting bioresorbable polylactide scaffold in comparison with the cobalt-chromium metallic stent?
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2017, Aug-04, Volume: 13, Issue:5

    Topics: Absorbable Implants; Cardiovascular Agents; Chromium; Cobalt; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Humans; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Sirolimus

2017
First-in-man study of dedicated bifurcation cobalt-chromium sirolimus-eluting stent BiOSS LIM C® - three-month results.
    Kardiologia polska, 2018, Volume: 76, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Angina, Stable; Chromium; Cobalt; Coronary Stenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Poland; Registries; Sirolimus; Treatment Outcome

2018
Sustained drug release using cobalt oxide nanowires for the preparation of polymer-free drug-eluting stents.
    Journal of biomaterials applications, 2018, Volume: 33, Issue:3

    Topics: Alloys; Anti-Infective Agents; Chromium; Cobalt; Delayed-Action Preparations; Drug Liberation; Drug-Eluting Stents; Nanowires; Oxides; Sirolimus

2018
Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice.
    Scientific reports, 2018, 10-02, Volume: 8, Issue:1

    Topics: Adenine; Animals; Autophagosomes; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Chromones; Cobalt; Disease Models, Animal; Erythropoietin; Humans; Liver; Liver Function Tests; Mice; Mice, Inbred C57BL; Morpholines; Peptide Fragments; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2018
Impact of Residual Stenosis on the Angiographic Edge Restenosis of a Second-Generation Drug-Eluting Stent.
    International heart journal, 2019, Sep-27, Volume: 60, Issue:5

    Topics: Age Factors; Aged; Angioplasty, Balloon, Coronary; Chromium; Cobalt; Cohort Studies; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Drug-Eluting Stents; Equipment Failure Analysis; Female; Hospitals, University; Humans; Incidence; Japan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Product Surveillance, Postmarketing; Prognosis; Prosthesis Design; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Sirolimus; Survival Analysis; Treatment Outcome

2019
Serum Sirolimus Levels After Implantation of Third Generation Drug Eluting Cobalt Chromium Coronary Stent in Ductus Arteriosus in Neonates with Duct-Dependent Pulmonary Circulation.
    Pediatric cardiology, 2020, Volume: 41, Issue:7

    Topics: Chromium; Cobalt; Drug-Eluting Stents; Ductus Arteriosus, Patent; Female; Heart Ventricles; Humans; Immunosuppressive Agents; Infant, Newborn; Male; Prospective Studies; Prosthesis Implantation; Pulmonary Atresia; Pulmonary Circulation; Sirolimus; Treatment Outcome; Ventricular Septum

2020
Sirolimus-eluting cobalt-chrome alloy stent suppresses stent-induced tissue hyperplasia in a porcine Eustachian tube model.
    Scientific reports, 2022, 03-02, Volume: 12, Issue:1

    Topics: Animals; Chromium Alloys; Cobalt; Drug-Eluting Stents; Eustachian Tube; Hyperplasia; Sirolimus; Stents; Swine; Treatment Outcome

2022