Page last updated: 2024-08-26

cobalt and losartan potassium

cobalt has been researched along with losartan potassium in 144 studies

Research

Studies (144)

TimeframeStudies, this research(%)All Research%
pre-199078 (54.17)18.7374
1990's42 (29.17)18.2507
2000's13 (9.03)29.6817
2010's10 (6.94)24.3611
2020's1 (0.69)2.80

Authors

AuthorsStudies
Lange, RD1
Fisher, JW; Smith, RJ2
Fisher, JW; George, WJ; Rodgers, GM5
Boll, I1
gardner, FH; Gorshein, D; Reisner, EH1
Kubanek, B1
Mirand, EA; Murphy, GP; Varkarakis, MJ1
Camiscoli, JF; Gordon, AS; MacPherson, GG; Murphy, MJ1
Gross, J; Necas, E; Neuwirt, J1
Fried, W1
Brookins, J; Fisher, JW; Nakashima, J1
Bauer, C; Dittmer, J1
Beck, I; Caro, J; Costa-Giomi, P; Ramirez, S; Schuster, SJ1
Abraham, NG; Beru, N; Goldwasser, E; Hermine, O; Levere, RD; Lin, JH1
Jones, RW; Pugh, CW; Ratcliffe, PJ; Tan, CC1
Bunn, HF; Doweiko, J; Goldberg, MA; Imagawa, S1
Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP1
Buerk, DG; Di Giulio, C; Huang, WX; Lahiri, S; Mokashi, A1
Beru, N; Goldwasser, E; Smith, D1
Bunn, HF; Dunning, SP; Goldberg, MA2
Caro, J; Erslev, AJ; Kaufman, R; Nielsen, OJ; Schuster, SJ1
Badiavas, EV; Caro, J; Costa-Giomi, P; Erslev, AJ; Schuster, SJ; Weinmann, R1
Bauer, C; Jelkmann, W; Kurtz, A; Malmström, K; Pfuhl, A1
Chhabra, R; Datta, K; Singh, NK1
Beru, N; Goldwasser, E; Lacombe, C; McDonald, J1
Jelkmann, W1
Kazakov, VN; Krizhanovskaia, EV; Makarov, VP; Nefedov, VP; Tashenov, EK1
Kuratowska, Z1
Fisher, JW2
Fisher, JW; Heidger, PM; Ignarro, LJ; Smith, RJ1
Heinecke, G; Schulz, E1
Siciński, A1
Contrera, JF; Smith, RJ2
Banerjee, RK; Chowdhury, RR; Datta, AG1
Chowdhury, RR; Datta, AG1
Klucik, I; Palkovicová, M1
Thorling, EB1
Fisher, JW; Ignarro, LJ; Smith, RJ1
Moiseeva, OI1
Flanagan, P; Howard, D; Miller, ME; Stohlman, F1
Gurney, CW1
Groenewald, JH; Kenny, GM; Mirand, EA; Murphy, GP2
Bernier, GM; Conrad, ME; Felsher, BF; Schade, SG1
Goldwasser, E1
Naets, JP; Wittek, M2
Erslev, AJ; Thorling, EB1
Bernardelli, E; Osvaldo, A1
Fisher, JW; Langston, JW2
Mazur, A2
Curry, JL; Trentin, JJ; Wolf, N1
Pavlov, AD2
Fimian, WJ; Howard, D; Rencricca, NJ; Rizzoli, V; Solomon, J; Stohlman, F1
Bourgoignie, JJ; Donati, RM; Gallagher, NI; Kuhn, C; Perry, HM1
Boggs, DR; Cartwright, GE; Chervenick, PA; Marsh, JC; Wintrobe, MM1
Remmele, W1
Lindgren, I; Salmi, HA1
Atakhanov, EI; Iuldashev, UI1
Idel'son, LI1
Fried, W; Kilbridge, T1
Matsumoto, S2
Krehbiel, JD; Lund, JE; Weiss, DJ1
Beckman, B; Fisher, JW; George, WJ; Katsuoka, Y1
Bentley, DP1
Eckardt, KU; Gess, B; Göpfert, T; Kurtz, A2
Bauer, T; Caro, J; Minchenko, A; Salceda, S1
Ebert, BL; Firth, JD; Gleadle, JM; Ratcliffe, PJ1
Alibali, P; Gardner, A; Goldwasser, E1
Ebert, BL; Firth, JD; Pugh, CW; Ratcliffe, PJ1
Acker, H; Fandrey, J; Görlach, A; Holtermann, G1
Imagawa, S; Izumi, T; Miura, Y1
Blanchard, KL; Bunn, HF; Fandrey, J; Galson, DL; Goldberg, MA1
Semenza, GL; Wang, GL1
Goldberg, MA; Schneider, TJ1
Chang, TM; Koo, J1
Abraham, NG; Griffin, MO; Kappas, A; Levere, RD; Lutton, JD; Nishimura, M; Shibahara, S1
Maxwell, PH; Pugh, CW; Ratcliffe, PJ1
Imajoh-Ohmi, S; Kanegasaki, S; Ochiai, H; Tsuchiya, T; Ueda, M1
Ebert, BL; Gleadle, JM; Ratcliffe, PJ1
Bartlett, SM; Ebert, BL; Gleadle, JM; O'Rourke, JF; Poulton, J; Ratcliffe, PJ1
Buchwald, M; dos Santos, CC; Joenje, H; Kruyt, FA; Wevrick, R; Youssoufian, H1
Gess, B; Kurtz, A; Sandner, P; Wolf, K1
Blanchard, KL; Campbell, L; Hu, B; Wright, E1
Acker, H; Ehleben, W; Fandrey, J; Kummer, W; Porwol, T1
Acker, H; Ehleben, W; Fandrey, J; Frede, S; Jelkmann, W; Porwol, T1
Brink-Johnsen, T; Chen, J; Dunnack, LM; Leiter, JC; Ou, LC; Salceda, S; Schuster, SJ1
Prchal, JF; Prchal, JT; Stopka, T; Stopkova, P; Zivny, JH1
Acker, H; Ehleben, W; Fandrey, J; Porwol, T; Zierold, K1
Chandel, NS; Goldwasser, E; Maltepe, E; Mathieu, CE; Schumacker, PT; Simon, MC1
Agani, F; Semenza, GL1
Bauer, C; Gassmann, M; Marti, HH; Wenger, RH1
Bunn, HF; Goldberg, MA; Gu, J; Huang, LE; Willmore, WG1
Beru, N; Goldwasser, E; Mujais, SK; Pullman, TN1
Bradfield, CA; Chan, WK; Gu, YZ; Yao, G1
Daghman, NA; Elder, GE; Lappin, TR; Maxwell, AP; Savage, GA; Winter, PC1
Baraban, JM; Hall, D; Lin, KI; Marquis, JC; Miller, MP; O'Donovan, K; Ratan, RR; Ryu, H; Semenza, GL; Zaman, K1
Kambe, T; Masuda, S; Moon, SK; Nagao, M; Sasaki, R1
Bunn, HF; Horiguchi, H; Hradecky, P; Kayama, F; Oguma, E; Willmore, WG1
Bergeron, M; Jones, NM1
Cicutti, N; Kolar, F; Rakusan, K1
Buczko, W; Koda, M; Pawlak, D; Pawlak, S; Wolczynski, S1
FRIED, W; GOLDWASSER, E; JACOBSON, LO; PLZAK, LF1
BROWN, TE; MEINEKE, HA1
NAETS, JP1
FISHER, JW; SANZARI, NP1
COUCH, C; FISHER, JW; NIGHTINGALE, WO; ROH, BL1
FISHER, JW; ROH, BL; SHENEP, K1
AZUMA, M; NAKAO, K; SHIRAKURA, T1
JENSEN, K; THORLING, EB1
NORGELLO, H; SCHLUETER, RJ; WHITE, WF1
Funae, Y; Imaoka, S; Katsumura, S; Kubo, T; Maezawa, N; Osada, M1
Funae, Y; Imaoka, S; Osada, M1
Acs, G; Elder, DE; Fang, D; Herlyn, M; Kumar, SM; Xu, X1
Fujita, T; Inagi, R; Kojima, I; Matsumoto, M; Miyata, T; Nangaku, M; Ohse, T; Tanaka, T1
Francis, GL; Helms, A; Oakley, K; Patel, A; Tuttle, RM; Yates, CM1
Eckardt, KU; Nangaku, M1
Bansal, A; Ilavazhagan, G; Ram, MS; Shrivastava, K; Singh, SS1
Hirahara, F; Koizume, S; Miyagi, E; Miyagi, Y; Tsuchiya, E; Yokota, N1
Bansal, A; Saxena, S; Shukla, D; Singh, M; Thomas, P1
Brusco, A; Caltana, L; Girimonti, P; Lazarowski, A; Merelli, A; Ramos, AJ1
Chiang, CK; Fujita, T; Inagi, R; Nangaku, M; Tanaka, T1
Deng, DB; Mo, SJ; Zhang, XQ; Zhong, Q; Zhou, YF1
Chiang, CK; Inagi, R; Iwawaki, T; Nangaku, M; Tanaka, T1
Chamorro, ME; Nesse, AB; Vittori, DC; Wenker, SD1
Elliott, JP; Jones, SM; Novak, AE1
Befani, C; Georgoulias, P; Gkotinakou, IM; Hu, CJ; Liakos, P; Mylonis, I; Simos, G1
GARCIA, JF; SCHOOLEY, JC1
Gong, KR; Ji, XM; Lu, GW; Meister, EA; Shao, G; Wang, X; Yan, SC; Zhang, YB1
Chen, D; Chen, Z; Dai, C; Han, Z; He, F; Li, Y; Tan, R; Tian, H; Wang, G; Wang, M; Wei, L; Yang, B; Yang, H; Zhang, B1
Knoop, A; Planitz, P; Thevis, M; Wüst, B1

Reviews

11 review(s) available for cobalt and losartan potassium

ArticleYear
Erythrocytosis associated with normal blood-gas values.
    Advances in internal medicine, 1976, Volume: 21

    Topics: Alkylating Agents; Androgens; Blood; Bloodletting; Carbon Dioxide; Cobalt; Erythropoiesis; Erythropoietin; Humans; Hydrogen-Ion Concentration; Oxygen; Phosphorus Radioisotopes; Polycythemia; Polycythemia Vera

1976
The role of renal adenosine 3',5'-monophosphate in the control of erythropoietin production.
    The American journal of medicine, 1975, Volume: 58, Issue:1

    Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Bucladesine; Cobalt; Cyclic AMP; Cyclic GMP; Enzyme Activation; Erythropoietin; Humans; Hypoxia; Kidney; Kidney Cortex; Mice; Phosphoric Diester Hydrolases; Prostaglandins; Protein Kinases; Rats; Stimulation, Chemical; Theophylline

1975
Erythropoietin and the kidney.
    Nephron, 1975, Volume: 15, Issue:3-5

    Topics: Anemia; Animals; Cobalt; Dactinomycin; Erythropoiesis; Erythropoietin; Hormones; Humans; Kidney; Kidney Failure, Chronic; Mice; Oxygen Consumption; Polycythemia; Rats

1975
Regulation of erythropoietin gene expression.
    Seminars in hematology, 1991, Volume: 28, Issue:3 Suppl 3

    Topics: Anemia; Animals; Blotting, Northern; Cobalt; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia; Mice; Rats; Restriction Mapping; RNA; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1991
Renal erythropoietin: properties and production.
    Reviews of physiology, biochemistry and pharmacology, 1986, Volume: 104

    Topics: Animals; Cobalt; Erythropoiesis; Erythropoietin; Hormones; Humans; Hypoxia; Kidney; Oxygen

1986
Erythropoietin: pharmacology, biogenesis and control of production.
    Pharmacological reviews, 1972, Volume: 24, Issue:3

    Topics: Adrenal Cortex Hormones; Androgens; Anemia; Angiotensin II; Chemical Phenomena; Chemistry; Cobalt; Cyclic AMP; Erythropoiesis; Erythropoietin; Humans; Juxtaglomerular Apparatus; Kidney; Nervous System Physiological Phenomena; Norepinephrine; Oxygen; Polycythemia; Prostaglandins; Serotonin; Thyroid Hormones; Vasopressins

1972
[Treatment of anemia in renal failure].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1974, Nov-04, Volume: 29, Issue:44

    Topics: Acute Kidney Injury; Androgens; Anemia; Blood Transfusion; Cobalt; Erythropoietin; Female; Humans; Iron; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Renal Dialysis; Sex Factors

1974
Erythropoietin.
    Advances in metabolic disorders, 1968, Volume: 3

    Topics: Anemia; Animals; Cobalt; Erythropoiesis; Erythropoietin; Humans; Hypophysectomy; Kidney; Mice; Pituitary Gland; Rabbits; Rats

1968
Biochemical control of erythroid cell development.
    Current topics in developmental biology, 1966, Volume: 1

    Topics: 5-Aminolevulinate Synthetase; Animals; Cell Differentiation; Cobalt; Dactinomycin; Erythropoiesis; Erythropoietin; Genes, Regulator; Glucosamine; Glycols; Hematopoietic Stem Cells; Heme; Hemoglobins; In Vitro Techniques; Models, Biological; Pituitary Gland; Rats; Reticulocytes; RNA; Steroids; Thyroid Hormones

1966
Cis elements that regulate the erythropoietin gene.
    Annals of the New York Academy of Sciences, 1994, Apr-15, Volume: 718

    Topics: Animals; Cell Line; Cobalt; Erythropoietin; Exons; Gene Expression Regulation; Humans; Mice; Oxygen; Regulatory Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Transfection

1994
Hypoxia and the HIF system in kidney disease.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:12

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cobalt; Erythropoietin; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Iron Chelating Agents; Kidney; Kidney Diseases; Oxygen; Signal Transduction

2007

Other Studies

133 other study(ies) available for cobalt and losartan potassium

ArticleYear
Neutral protease activity and erythropoietin production in the rat after cobalt administration.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Animals; Cathepsins; Cobalt; Erythropoietin; Hydrogen-Ion Concentration; Isoflurophate; Kidney; Male; Mitochondria; Peptide Hydrolases; Rats; Time Factors

1976
Renal cyclic GMP and cholinergic mechanisms in erythropoietin production.
    Life sciences, 1975, Dec-15, Volume: 17, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Cobalt; Cyclic GMP; Drug Synergism; Erythropoietin; Glucuronidase; Kidney; Lysosomes; Male; Physostigmine; Rats

1975
[Regulation of the human erythropoietic proliferation pool by the microenvironment (author's transl)].
    Klinische Wochenschrift, 1978, Feb-15, Volume: 56, Issue:4

    Topics: Androgens; Cobalt; Culture Media; Cyclic AMP; Erythropoiesis; Erythropoietin; Etiocholanolone; Folic Acid; Hematopoiesis; Humans; Mitosis; Polycythemia Vera

1978
Tissue culture of bone marrow. V. Effect of 5Beta(H) steroids and cyclic AMP on heme synthesis.
    The American journal of physiology, 1975, Volume: 228, Issue:4

    Topics: Androstanes; Bone Marrow; Bucladesine; Calcium; Cobalt; Culture Techniques; Cyclic AMP; Cyproterone; Drug Synergism; Erythropoiesis; Erythropoietin; Heme; Humans; Hydroxysteroids; Immune Sera; Ketosteroids; Pregnanediones; Pregnanes; Pregnanolone; Stimulation, Chemical; Theophylline

1975
[Conservative treatment of infection and tumor anemia].
    Deutsche medizinische Wochenschrift (1946), 1979, Feb-16, Volume: 104, Issue:7

    Topics: Anemia; Blood Transfusion; Chlorides; Cobalt; Collagen Diseases; Erythropoietin; Humans; Iron; Neoplasms; Testosterone

1979
The response of the juxtaglomerular apparatus to stimuli effecting renin or erythropoietin release in canine renal allografts.
    Investigative urology, 1976, Volume: 13, Issue:5

    Topics: Animals; Azathioprine; Blood Pressure; Cobalt; Diet; Dogs; Erythropoietin; Female; Graft Rejection; Hypoxia; Juxtaglomerular Apparatus; Kidney Transplantation; Male; Renin; Sodium Chloride; Testosterone; Transplantation, Homologous

1976
Erythropoietin in renal and hepatic lymph of conscious ewes.
    Experimental hematology, 1977, Volume: 5, Issue:1

    Topics: Anemia, Hemolytic; Animals; Cobalt; Erythropoietin; Female; Hydronephrosis; Kidney; Liver; Lymph; Mice; Phenylhydrazines; Renal Artery Obstruction; Sheep

1977
Species specificity of guinea pig erythropoietin.
    Endocrinologia experimentalis, 1976, Volume: 10, Issue:4

    Topics: Animals; Bloodletting; Carbon Monoxide Poisoning; Cobalt; Erythropoietin; Female; Guinea Pigs; Hypoxia; Kidney; Mice; Nephrectomy; Rats; Species Specificity

1976
Characterization of erythropoietin production in a hepatocellular carcinoma cell line.
    The Journal of laboratory and clinical medicine, 1992, Volume: 119, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carcinoma, Hepatocellular; Cobalt; Colforsin; Cyclic AMP; Erythropoietin; Humans; Hypoxia; Liver Neoplasms; Tumor Cells, Cultured

1992
Inhibitory effect of zinc on stimulated erythropoietin synthesis in HepG2 cells.
    The Biochemical journal, 1992, Jul-01, Volume: 285 ( Pt 1)

    Topics: Blotting, Northern; Cadmium; Carcinoma, Hepatocellular; Cations, Divalent; Cell Hypoxia; Cobalt; Depression, Chemical; Erythropoietin; Nickel; RNA, Messenger; Tumor Cells, Cultured; Zinc

1992
Co-regulation of heme oxygenase and erythropoietin genes.
    Journal of cellular biochemistry, 1991, Volume: 47, Issue:1

    Topics: Animals; Base Sequence; Blotting, Northern; Cobalt; Erythropoietin; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Kidney; Kinetics; Male; Molecular Sequence Data; Polydeoxyribonucleotides; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic

1991
Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Dec-01, Volume: 88, Issue:23

    Topics: Animals; Base Sequence; Cell Line; CHO Cells; Cloning, Molecular; Cobalt; Cricetinae; Cyanides; Deoxyglucose; Enhancer Elements, Genetic; Erythropoietin; Escherichia coli; Gene Expression Regulation; Globins; Male; Mice; Molecular Sequence Data; Oxygen; Plasmids; Recombinant Fusion Proteins; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Transfection

1991
Regulatory elements of the erythropoietin gene.
    Blood, 1991, Jan-15, Volume: 77, Issue:2

    Topics: Animals; Cell Line; Chlorocebus aethiops; Cobalt; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia; In Vitro Techniques; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Transfection

1991
Role of cytochrome P450 in the control of the production of erythropoietin.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured

1990
Cobalt stimulates carotid body chemoreceptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:5

    Topics: Animals; Calcium; Carotid Body; Cats; Chemoreceptor Cells; Cobalt; Electrophysiology; Erythropoietin; Hypoxia; Oxygen

1990
Evidence suggesting negative regulation of the erythropoietin gene by ribonucleoprotein.
    The Journal of biological chemistry, 1990, Aug-25, Volume: 265, Issue:24

    Topics: Animals; Base Sequence; Cell Nucleus; Cobalt; Erythropoietin; Female; Gene Expression Regulation; Humans; Kidney; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligonucleotide Probes; Reference Values; Ribonucleoproteins; Sequence Homology, Nucleic Acid

1990
Oxygen sensing and erythropoietin gene regulation in a human hepatoma cell line.
    Progress in clinical and biological research, 1989, Volume: 319

    Topics: Animals; Biological Assay; Blotting, Northern; Carcinoma, Hepatocellular; Cell Hypoxia; Cobalt; Erythropoietin; Gene Expression Regulation, Neoplastic; Hemeproteins; Humans; Liver Neoplasms; Manganese; Mice; Neoplasm Proteins; Nickel; Oxygen; Radioimmunoassay; RNA, Messenger; Second Messenger Systems; Tumor Cells, Cultured

1989
Regulation of erythropoietin production in a human hepatoblastoma cell line.
    Blood, 1987, Volume: 70, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cobalt; Cricetinae; Erythropoietin; Glycosylation; Humans; Hypoxia; Liver Neoplasms; Protein Processing, Post-Translational; RNA, Messenger; Transfection; Tumor Cells, Cultured; Tunicamycin

1987
Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein.
    Science (New York, N.Y.), 1988, Dec-09, Volume: 242, Issue:4884

    Topics: Anaerobiosis; Carbon Monoxide; Carcinoma, Hepatocellular; Cell Line; Cobalt; Cycloheximide; Erythropoietin; Gene Expression Regulation; Genes; Hemeproteins; Humans; Iron; Liver Neoplasms; Manganese; Nickel; Transcription, Genetic

1988
Stimulation of erythropoietin gene transcription during hypoxia and cobalt exposure.
    Blood, 1989, Volume: 73, Issue:1

    Topics: Animals; Cobalt; Erythropoietin; Gene Expression Regulation; Hypoxia; Kidney; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic

1989
Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cobalt; Colforsin; Cyclic AMP; Enzyme Activation; Erythropoietin; Isoproterenol; Kinetics; Lactates; Lactic Acid; Liver; Mice; Oxygen

1986
Induction of L-alanine:4,5-dioxovalerate transaminase by phenylhydrazine is associated with depletion of heme level.
    Biochemical and biophysical research communications, 1986, Jul-31, Volume: 138, Issue:2

    Topics: Anemia; Animals; Cobalt; Dactinomycin; Erythropoietin; Hematocrit; Heme; Immune Sera; Immunodiffusion; Kidney; Kinetics; Liver; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Transaminases

1986
Expression of the erythropoietin gene.
    Molecular and cellular biology, 1986, Volume: 6, Issue:7

    Topics: Animals; Cobalt; Erythropoietin; Gene Expression Regulation; Hemorrhage; Kidney; Leukemia, Erythroblastic, Acute; Liver; Male; Rats; RNA, Messenger; Time Factors

1986
[Assessment of the erythropoietin-producing function of the kidney and liver under controlled perfusion].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 102, Issue:10

    Topics: Animals; Cobalt; Dogs; Erythropoiesis; Erythropoietin; Hemorrhage; Kidney; Liver; Male; Mice; Mice, Inbred CBA; Perfusion; Polycythemia

1986
The renal mechanism of the formation and inactivation of erythropoietin.
    Annals of the New York Academy of Sciences, 1968, Mar-29, Volume: 149, Issue:1

    Topics: Alpha-Globulins; Androgens; Animals; Biological Assay; Cobalt; Erythrocytes; Erythropoietin; Hematocrit; Hypothalamus; Hypoxia; Iron Isotopes; Kidney; Liver; Oxygen; Rabbits; Rats

1968
Increased kidney cyclic AMP levels and erythropoietin production following cobalt administration.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:3

    Topics: Animals; Butyrates; Cobalt; Cyclic AMP; Erythropoiesis; Erythropoietin; Hypoxia; Iron; Iron Isotopes; Kidney; Male; Polycythemia; Rats; Stimulation, Chemical

1972
Effects of cobalt on the renal erythropoietic factor and kidney hydrolase activity in the rat.
    Blood, 1973, Volume: 42, Issue:6

    Topics: Acid Phosphatase; Alkaline Phosphatase; Aminocaproates; Animals; Aprotinin; Blood Proteins; Cathepsins; Cobalt; Electron Transport Complex IV; Erythrocyte Count; Erythropoiesis; Erythropoietin; Female; Iron Radioisotopes; Isoflurophate; Kidney; Male; Mercaptoethanol; Mice; Mitochondria; Polycythemia; Propionates; Rats; Sulfhydryl Compounds; Thiocarbamates

1973
Elevation of renal cyclic GMP concentrations and plasma lysosomal enzyme activity following cobalt treatment in rats.
    Biochemical and biophysical research communications, 1974, Aug-05, Volume: 59, Issue:3

    Topics: Acid Phosphatase; Aluminum; Animals; Chromatography; Chromatography, Ion Exchange; Cobalt; Cyclic GMP; Erythropoietin; Glucuronidase; Kidney; Lysosomes; Male; Nephrectomy; Radioimmunoassay; Rats; Time Factors

1974
Lactate stimulation of renal cortical adenylate cyclase: a mechanism for erythropoietin production following cobalt treatment or hypoxia.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cobalt; Cyclic AMP; Erythropoiesis; Erythropoietin; Hypoxia; Iron; Iron Radioisotopes; Kidney Cortex; Kidney Medulla; Lactates; Male; NAD; Phosphorus Radioisotopes; Polycythemia; Pyruvates; Rats; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors; Tritium

1974
Lysosomal enzyme release in vivo: an evaluation of the mechanism of cobalt polycythemia.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:3

    Topics: Acid Phosphatase; Animals; Cobalt; Erythropoiesis; Erythropoietin; Female; Glucuronidase; Histocytochemistry; Hypoxia; Iron; Kidney; Lysosomes; Male; Manganese; Membranes; Mice; Microscopy, Electron; Mitochondria; Nephrectomy; Nickel; Polycythemia; Rats

1974
[Prevention and therapy of renal anemia].
    Deutsche medizinische Wochenschrift (1946), 1973, May-18, Volume: 98, Issue:20

    Topics: Anemia, Hemolytic; Blood Transfusion; Chlorides; Cobalt; Erythropoietin; Follow-Up Studies; Hematocrit; Humans; Iron; Kidney Failure, Chronic; Kidney Transplantation; Renal Dialysis; Testosterone; Transplantation, Homologous

1973
The effect of cobalt on erythropoietin and kininogen levels in rat plasma.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:3

    Topics: Animals; Atmosphere Exposure Chambers; Biological Assay; Chlorides; Cobalt; Erythrocytes; Erythropoietin; Female; Injections, Subcutaneous; Iron; Iron Isotopes; Kininogens; Kinins; Male; Mice; Polycythemia; Protein Precursors; Rats; Time Factors; Uterus

1972
Effect of erythropoietin on the peroxidase and tyrosine-iodinase activity of mouse thyroid and submaxillary gland.
    European journal of biochemistry, 1973, Apr-02, Volume: 34, Issue:1

    Topics: Animals; Cobalt; Cobalt Isotopes; Enzyme Induction; Erythrocytes; Erythropoietin; Iron; Iron Isotopes; Kidney; Male; Mice; Monoiodotyrosine; Neuraminidase; Peroxidases; Rats; Sheep; Starvation; Submandibular Gland; Thyroid Gland; Vitamin B 12

1973
Studies on the in vitro formation of erythropoietin in sheep kidney medulla and the effect of cobalt thereon.
    Biochemical and biophysical research communications, 1973, Jun-19, Volume: 52, Issue:4

    Topics: Amino Acids; Animals; Carbon Isotopes; Cobalt; Cycloheximide; Dactinomycin; Drug Stability; Electrophoresis, Disc; Erythropoietin; Hot Temperature; In Vitro Techniques; Juxtaglomerular Apparatus; Kidney; Kidney Cortex; Kidney Medulla; Phenylalanine; Precipitin Tests; Sheep

1973
[Level of erythropoietin in the serum of employees of the hydrometallurgical production of cobalt].
    Bratislavske lekarske listy, 1973, Volume: 59, Issue:4

    Topics: Cobalt; Erythropoietin; Humans; Metallurgy; Occupational Diseases

1973
A comparison of the cobalt, methylene blue, zinc, arsenite and amino triazole effect on erythropoietin production.
    British journal of haematology, 1973, Volume: 25, Issue:1

    Topics: Animals; Arsenic; Biological Assay; Cobalt; Erythropoietin; Female; Hypoxia; Iron; Iron Isotopes; Male; Methylene Blue; Mice; Polycythemia; Rabbits; Stimulation, Chemical; Triazoles; Zinc

1973
Lysosomal enzyme release: a possible mechanism of action of cobalt as an erythropoietic stimulant.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 146, Issue:3

    Topics: Acid Phosphatase; Animals; Cobalt; Erythropoiesis; Erythropoietin; Glucuronidase; In Vitro Techniques; Iron; Kidney; Lysosomes; Male; Manganese; Membranes; Nickel; Rats; Time Factors

1974
[Erythropoietic properties of a homogenate of kidney and its subcellular fractions].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1974, Volume: 60, Issue:1

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cobalt; Depression, Chemical; Erythropoietin; Hemorrhage; Kidney; Microsomes; Mitochondria; Mitosis; Rabbits; Rats; Stimulation, Chemical; Tissue Extracts

1974
Mechanism of erythropoietin production by cobaltous chloride.
    Blood, 1974, Volume: 44, Issue:3

    Topics: Alkalosis, Respiratory; Animals; Carbon Dioxide; Carboxyhemoglobin; Chlorides; Cobalt; Dose-Response Relationship, Drug; Erythropoietin; Female; Hydrogen-Ion Concentration; Iron Radioisotopes; Male; Nephrectomy; Oxygen; Partial Pressure; Rats; Spectrophotometry

1974
Cobalt-induced alterations in plasma proteins, proteases and kinin system of the rat.
    Biochemical pharmacology, 1974, Mar-15, Volume: 23, Issue:6

    Topics: Animals; Arginine; Blood Proteins; Bradykinin; Caseins; Cobalt; Erythropoietin; Esterases; Female; Hydrolysis; Kininogens; Kinins; Male; Peptide Hydrolases; Rats; Stimulation, Chemical; Time Factors; Uterus

1974
Erythropoietin activity in autotransplanted canine kidneys.
    Archives of surgery (Chicago, Ill. : 1960), 1969, Volume: 99, Issue:5

    Topics: Animals; Cobalt; Dogs; Erythropoietin; Female; Hemorrhage; Hypoxia; Iron Isotopes; Kidney; Kidney Transplantation; Male; Mice; Testosterone; Transplantation, Autologous

1969
Response of renal allografts to erythropoietic stimuli in the presence of immunosuppression.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 100, Issue:1

    Topics: Androgens; Animals; Azathioprine; Blood Urea Nitrogen; Cobalt; Dogs; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hypoxia; Immunosuppressive Agents; Kidney Transplantation; Leukocyte Count; Male; Tissue Extracts; Urination

1970
Interrelationship of cobalt and iron absorption.
    The Journal of laboratory and clinical medicine, 1970, Volume: 75, Issue:3

    Topics: Animals; Ascorbic Acid; Cobalt; Cobalt Isotopes; Deficiency Diseases; Endotoxins; Erythropoietin; Escherichia coli; Ferritins; Immunoassay; Intestinal Absorption; Iron; Iron Isotopes; Iron-Dextran Complex; Male; Rabbits; Rats

1970
Effect of erythroid hyperplasia on the disappearance rate of erythropoietin in the dog.
    Acta haematologica, 1968, Volume: 39, Issue:1

    Topics: Animals; Blood Cell Count; Bone Marrow Diseases; Bone Marrow Examination; Cobalt; Cobalt Isotopes; Dogs; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hemoglobinometry; Hyperplasia; Male; Mice; Nephrectomy; Phenylhydrazines; Reticulocytes

1968
The effect of some erythropoietic agents on the 'tissue' tension of oxygen.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Animals; Blood Transfusion; Cobalt; Erythropoiesis; Erythropoietin; Female; Hemolysis; Iron; Iron Isotopes; Male; Nandrolone; Norethandrolone; Oxygen; Oxygen Consumption; Partial Pressure; Rats; Testosterone

1972
[Research on the pathogenesis of avian erythremia].
    Schweizerische medizinische Wochenschrift, 1965, Oct-30, Volume: 95, Issue:44

    Topics: Animals; Chick Embryo; Cobalt; Erythropoietin; Leukemia, Erythroblastic, Acute; Nandrolone; Poultry; Prednisone; Vitamin B 12

1965
Effects of testosterone, cobalt and hypoxia on erythropoietin production in the isolated perfused dog kidney.
    Annals of the New York Academy of Sciences, 1968, Mar-29, Volume: 149, Issue:1

    Topics: Animals; Biological Assay; Cobalt; Dogs; Erythrocytes; Erythropoietin; Female; Hypoxia; Iron; Iron Isotopes; Kidney; Kidney Glomerulus; Male; Mice; Oximetry; Oxygen; Perfusion; Testosterone

1968
Role of the spleen in iron metabolism.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Animals; Bone Marrow; Carbon Isotopes; Cobalt; Enzymes; Erythrocytes; Erythropoietin; Glycine; Heme; Hemorrhage; Histones; Iron; Iron Isotopes; Liver; Lyases; Lymphoma, Non-Hodgkin; Lysine; Phenylhydrazines; Porphyrins; Radiation Effects; Rats; Reticulocytes; Spleen

1969
Hemopoietic spleen colony studies. II. Erythropoiesis.
    The Journal of experimental medicine, 1967, Apr-01, Volume: 125, Issue:4

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cobalt; Erythropoiesis; Erythropoietin; Mice; Polycythemia; Radiation Effects; Sodium Chloride; Spleen

1967
[Effect of erythropoietic stimuli on ribonucleic acid synthesis in bone marrow].
    Ukrains'kyi biokhimichnyi zhurnal, 1969, Volume: 41, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cobalt; DNA; Enzyme Repression; Erythropoiesis; Erythropoietin; Hemorrhage; Phenylhydrazines; Phosphorus; Phosphorus Isotopes; Rabbits; Ribosomes; RNA; RNA, Transfer; Stimulation, Chemical

1969
Molecular aspect of action of endogenous erythropoietin. The effects of erythropoietic stimuli on synthesis of ribonucleic acids in rabbit bone marrow.
    Biochimica et biophysica acta, 1969, Nov-19, Volume: 195, Issue:1

    Topics: Animals; Bloodletting; Bone Marrow; Cobalt; DNA; Erythrocyte Count; Erythropoiesis; Erythropoietin; Femur; Forelimb; Hematocrit; Hemoglobins; Iron Isotopes; Phenylhydrazines; Phosphates; Phosphorus Isotopes; Rabbits; Reticulocytes; Ribosomes; RNA; RNA, Transfer; Stimulation, Chemical; Templates, Genetic; Tibia; Time Factors

1969
The effect of testosterone on erythropoiesis.
    Scandinavian journal of haematology, 1969, Volume: 6, Issue:6

    Topics: Animals; Cobalt; Erythropoiesis; Erythropoietin; Iron Isotopes; Kidney; Nephrectomy; Polycythemia; Rats; Testosterone; Tissue Extracts; Ureter

1969
Dissociation of circulating renin and erythropoietin in rats.
    Circulation research, 1968, Volume: 22, Issue:1

    Topics: Animals; Chlorides; Cobalt; Erythropoietin; Hypoxia; Injections, Intraperitoneal; Oxygen Consumption; Polythiazide; Rats; Renin; Sodium Chloride; Water-Electrolyte Balance

1968
Factors influencing hematopoietic spleen colony formation in irradiated mice. IV. The effect of erythropoietic stimuli.
    Journal of cellular physiology, 1968, Volume: 71, Issue:1

    Topics: Animals; Cobalt; Culture Techniques; Erythropoiesis; Erythropoietin; Hemorrhage; Iron; Mice; Organ Size; Radiation Effects; Spleen; Splenectomy; Testosterone

1968
Metabolism of the stimulated rat spleen. I. Ferrochelatase activity as an index of tissue erythropoiesis.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:10

    Topics: Animals; Bone Marrow; Carbon Isotopes; Carcinoma 256, Walker; Chlorides; Cobalt; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Ferritins; Glycine; Hemoglobins; Iron Isotopes; Liver; Lyases; Phenylhydrazines; Rats; RNA; Spleen; Stimulation, Chemical

1968
[Erythropoietin].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Adult; Anemia; Animals; Chickens; Child, Preschool; Cobalt; Erythropoiesis; Erythropoietin; Gonadal Steroid Hormones; Humans; Infant, Newborn; Juxtaglomerular Apparatus; Mice; Rabbits; Rats

1968
Cobalt in the human organism. Experiments on retention of 60-Co in patients with normal and glomerulonephritic kidneys.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:1

    Topics: Adult; Aged; Autoradiography; Cobalt; Cobalt Isotopes; Erythropoiesis; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney; Kidney Function Tests; Liver; Male; Middle Aged

1968
[Hemopoetic factors in anemias of gastro-intestinal origin].
    Vestnik Akademii meditsinskikh nauk SSSR, 1968, Volume: 23, Issue:4

    Topics: Anemia; Cobalt; Erythropoietin; Gastric Juice; Gastrointestinal Diseases; Humans; Iron; Mucoproteins; Vitamin B 12

1968
[Normal and pathological hematopoiesis and porphyrin formation].
    Terapevticheskii arkhiv, 1968, Volume: 40, Issue:4

    Topics: Anemia, Sideroblastic; Animals; Ascorbic Acid; Cobalt; Erythropoiesis; Erythropoietin; Humans; Lead Poisoning; Porphyrias; Porphyrins; Rats

1968
Effect of testosterone and of cobalt on erythropoietin production by anephric rats.
    The Journal of laboratory and clinical medicine, 1969, Volume: 74, Issue:4

    Topics: Animals; Biological Assay; Blood Volume; Body Weight; Cobalt; Erythropoietin; Female; Hypoxia; Iron Isotopes; Kidney; Nephrectomy; Rats; Testosterone

1969
Effect of erythroid hyperplasia on utilization of erythropoietin.
    Nature, 1965, May-15, Volume: 206, Issue:985

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cobalt; Dogs; Erythropoietin; Hyperplasia; In Vitro Techniques; Nephrectomy

1965
[Erythropoiesis and cobalt. I. Studies on erythropoiesis stimulating mechanism of cobalt].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1965, Volume: 28, Issue:6

    Topics: Animals; Cobalt; Erythrocytes; Erythropoiesis; Erythropoietin; In Vitro Techniques; Injections, Intramuscular; Iron Isotopes; Rabbits; Rats

1965
[Erythropoiesis and cobalt. II. Studies on the mechanism of erythropoietin production by cobalt].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1965, Volume: 28, Issue:6

    Topics: Animals; Cobalt; Erythrocytes; Erythropoiesis; Erythropoietin; In Vitro Techniques; Injections, Intramuscular; Nephrectomy; Rabbits; Rats

1965
The influence of hypoxemia and cobalt on erythropoietin production in the isolated perfused dog kidney.
    Blood, 1967, Volume: 29, Issue:1

    Topics: Animals; Cobalt; Dogs; Erythropoietin; Hypoxia; Kidney; Perfusion

1967
Studies of the pathogenesis of anemia of inflammation: mechanism of impaired erythropoiesis.
    American journal of veterinary research, 1983, Volume: 44, Issue:10

    Topics: Anemia; Animals; Cat Diseases; Cats; Cobalt; Erythrocyte Count; Erythropoiesis; Erythropoietin; Ferric Compounds; Hematocrit; Inflammation; Iron; Reticulocytes; Time Factors; Turpentine

1983
Increased levels of erythropoietin in kidney extracts of rats treated with cobalt and hypoxia.
    The American journal of physiology, 1983, Volume: 244, Issue:2

    Topics: Animals; Cobalt; Erythropoiesis; Erythropoietin; Hypoxia; Kidney; Male; Rats; Rats, Inbred Strains

1983
Anaemia and chronic disease.
    Clinics in haematology, 1982, Volume: 11, Issue:2

    Topics: Anemia; Chronic Disease; Cobalt; Erythropoietin; Ferritins; Humans; Infusions, Parenteral; Intestinal Mucosa; Iron; Kinetics; Mononuclear Phagocyte System; Protoporphyrins

1982
Cobalt exerts opposite effects on erythropoietin gene expression in rat hepatocytes in vivo and in vitro.
    The American journal of physiology, 1995, Volume: 269, Issue:5 Pt 2

    Topics: Animals; Animals, Newborn; Carbon Monoxide; Cells, Cultured; Cobalt; Erythropoietin; Gene Expression; Hypoxia; In Vitro Techniques; Liver; Male; Oxygen; Rats; Rats, Sprague-Dawley; RNA, Messenger

1995
Hypoxia regulatory elements of the human vascular endothelial growth factor gene.
    Cellular & molecular biology research, 1994, Volume: 40, Issue:1

    Topics: Base Sequence; Cell Hypoxia; Cobalt; DNA; Endothelial Growth Factors; Enhancer Elements, Genetic; Erythropoietin; Genes, Regulator; HeLa Cells; Humans; Hypoxia; Lymphokines; Molecular Sequence Data; Neovascularization, Pathologic; Sequence Homology, Nucleic Acid; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1994
Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Angiogenesis Inducing Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line; Chelating Agents; Cobalt; Deferoxamine; Endothelial Growth Factors; Erythropoietin; Gene Expression Regulation, Neoplastic; Growth Substances; Humans; Liver Neoplasms; Lymphokines; Molecular Sequence Data; Neovascularization, Pathologic; Placenta Growth Factor; Platelet-Derived Growth Factor; Pregnancy Proteins; RNA, Messenger; RNA, Small Nuclear; Transforming Growth Factor beta; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1995
Differential inhibition by iodonium compounds of induced erythropoietin expression.
    The Journal of biological chemistry, 1995, Feb-10, Volume: 270, Issue:6

    Topics: Biphenyl Compounds; Cobalt; Erythropoietin; Onium Compounds; Tumor Cells, Cultured

1995
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jul-05, Volume: 91, Issue:14

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line; Cloning, Molecular; Cobalt; Cyanides; Cycloheximide; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Isoenzymes; L Cells; L-Lactate Dehydrogenase; Liver Neoplasms; Mice; Molecular Sequence Data; Oxygen; Phosphoglycerate Kinase; Promoter Regions, Genetic; Sequence Deletion; Sequence Homology, Nucleic Acid; TATA Box; Transfection; Tumor Cells, Cultured

1994
Effects of cobalt on haem proteins of erythropoietin-producing HepG2 cells in multicellular spheroid culture.
    FEBS letters, 1994, Jul-11, Volume: 348, Issue:2

    Topics: Cells, Cultured; Cobalt; Cytochromes; Erythropoietin; Hydrogen Peroxide; Oxidation-Reduction; Signal Transduction

1994
Positive and negative regulation of the erythropoietin gene.
    The Journal of biological chemistry, 1994, Mar-25, Volume: 269, Issue:12

    Topics: Base Sequence; Binding Sites; Cell Line; Cobalt; DNA Primers; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia; In Vitro Techniques; Molecular Sequence Data; Nuclear Proteins; Nucleic Acid Conformation; Oligonucleotides; Promoter Regions, Genetic; RNA, Messenger

1994
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction.
    Blood, 1993, Dec-15, Volume: 82, Issue:12

    Topics: Base Sequence; Cell Hypoxia; Cell Line; Cell Nucleus; Cobalt; Deferoxamine; DNA-Binding Proteins; Erythropoietin; Gene Expression; Hepatoblastoma; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Molecular Sequence Data; Nuclear Proteins; Oligonucleotide Probes; RNA, Neoplasm; Signal Transduction; Transcription Factors; Tumor Cells, Cultured

1993
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
    The Journal of biological chemistry, 1994, Feb-11, Volume: 269, Issue:6

    Topics: Animals; Cobalt; Cycloheximide; Endothelial Growth Factors; Erythropoietin; Gene Expression Regulation; Genes, fos; Genes, jun; Heme; Humans; Hypoxia; In Vitro Techniques; Lymphokines; Oxygen; Rats; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1994
Secretion of erythropoietin from microencapsulated rat kidney cells: preliminary results.
    The International journal of artificial organs, 1993, Volume: 16, Issue:7

    Topics: Alginates; Animals; Artificial Organs; Cell Survival; Cobalt; Culture Media; Diffusion Chambers, Culture; Drug Compounding; Erythropoietin; Kidney; Membranes, Artificial; Polylysine; Radioimmunoassay; Rats; Rats, Sprague-Dawley

1993
Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:5

    Topics: Carcinoma, Hepatocellular; Cobalt; Erythropoietin; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Humans; Liver Neoplasms; Metalloporphyrins; Protoporphyrins; RNA, Messenger; Tumor Cells, Cultured

1993
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Mar-15, Volume: 90, Issue:6

    Topics: Animals; Cell Hypoxia; Cell Line; Cobalt; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation; Humans; Organ Specificity; Oxygen; Plasmids; Restriction Mapping; Transfection; Tumor Cells, Cultured

1993
Erythropoietin 5'-flanking sequence-binding protein induced during hypoxia and cobalt exposure.
    Journal of biochemistry, 1993, Volume: 113, Issue:3

    Topics: Anemia; Animals; Base Sequence; Cell Line; Chromatography, Affinity; Cobalt; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Gene Expression; Humans; Hypoxia; Kidney; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data

1993
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
    European journal of biochemistry, 1995, Nov-15, Volume: 234, Issue:1

    Topics: Base Sequence; Biphenyl Compounds; Cobalt; Deferoxamine; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythropoietin; Gene Expression; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Sequence Data; Nuclear Proteins; Oligodeoxyribonucleotides; Onium Compounds; Oxygen; Transcription Factors; Tumor Cells, Cultured

1995
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin.
    The Biochemical journal, 1996, Feb-01, Volume: 313 ( Pt 3)

    Topics: Base Sequence; Cell Hypoxia; Cell Line; Cobalt; Deferoxamine; Energy Metabolism; Erythropoietin; Gene Expression Regulation; Glycolysis; HeLa Cells; Humans; Isoenzymes; Mitochondria; Molecular Sequence Data; Monosaccharide Transport Proteins; Oligonucleotide Probes; RNA, Messenger; Siderophores

1996
Expression of the Fanconi anemia gene FAC in human cell lines: lack of effect of oxygen tension.
    Blood cells, molecules & diseases, 1995, Volume: 21, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Hypoxia; Cell Line, Transformed; Cobalt; DNA-Binding Proteins; Erythropoietin; Fanconi Anemia; Fanconi Anemia Complementation Group C Protein; Fanconi Anemia Complementation Group Proteins; Gene Expression Regulation; Herpesvirus 4, Human; Humans; Liver Neoplasms; Lymphocytes; Nuclear Proteins; Oxygen; Protein Biosynthesis; Proteins; RNA, Messenger; Tumor Cells, Cultured

1995
Hypoxia signalling in the control of erythropoietin gene expression in rat hepatocytes.
    Journal of cellular physiology, 1996, Volume: 168, Issue:2

    Topics: Animals; Catalase; Cell Hypoxia; Cells, Cultured; Cobalt; Cycloheximide; Deferoxamine; DNA-Binding Proteins; Erythropoietin; Gene Expression Regulation; Hydrogen Peroxide; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Iron Chelating Agents; Liver; Male; Nuclear Proteins; Oxygen; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA; Signal Transduction; Transcription Factors

1996
Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:6

    Topics: Animals; Base Sequence; Carbon Monoxide; Cobalt; Endothelial Growth Factors; Erythropoietin; Gene Expression Regulation; Hypoxia; In Vitro Techniques; Lymphokines; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1996
In vivo analysis of DNA-protein interactions on the human erythropoietin enhancer.
    Molecular and cellular biology, 1997, Volume: 17, Issue:2

    Topics: Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Hypoxia; Cobalt; DNA; DNA Footprinting; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythropoietin; Genes; Humans; Molecular Sequence Data; Nucleic Acid Conformation; Polymerase Chain Reaction; Trans-Activators; Tumor Cells, Cultured

1997
Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells.
    Kidney international, 1997, Volume: 51, Issue:2

    Topics: Cell Line; Cobalt; Cytochromes; Deferoxamine; Erythropoietin; Fluorescent Dyes; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Models, Molecular; NADPH Oxidases; Oxygen; Oxygen Consumption; Reactive Oxygen Species; Rhodamine 123; Rhodamines

1997
Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species.
    Kidney international, 1997, Volume: 51, Issue:2

    Topics: Cell Line; Cobalt; Deferoxamine; Erythropoietin; Humans; Hydrogen Peroxide; NADP; Reactive Oxygen Species; Signal Transduction

1997
Polycythemic responses to hypoxia: molecular and genetic mechanisms of chronic mountain sickness.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Altitude Sickness; Animals; Blood Gas Analysis; Blotting, Northern; Chronic Disease; Cobalt; Erythropoietin; Feedback; Gene Expression Regulation; Hypoxia; Kidney; Kidney Function Tests; Male; Polycythemia; Rats; Rats, Sprague-Dawley; Ribonucleases

1998
Human hematopoietic progenitors express erythropoietin.
    Blood, 1998, May-15, Volume: 91, Issue:10

    Topics: Adult; Antigens, CD34; Base Sequence; Carcinoma, Hepatocellular; Cell Hypoxia; Cells, Cultured; Cobalt; Culture Media, Serum-Free; Enzyme-Linked Immunosorbent Assay; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Molecular Sequence Data; Peptides; Receptors, Erythropoietin; RNA, Messenger; Tumor Cells, Cultured

1998
The influence of nickel and cobalt on putative members of the oxygen-sensing pathway of erythropoietin-producing HepG2 cells.
    European journal of biochemistry, 1998, Aug-15, Volume: 256, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Compartmentation; Cobalt; Drug Interactions; Electron Probe Microanalysis; Erythropoietin; Free Radical Scavengers; Hemeproteins; Humans; Hydrogen Peroxide; Iron; Liver; Metals, Heavy; Microscopy, Confocal; Nickel; Oxygen; Oxygen Consumption; Reactive Oxygen Species; Signal Transduction; Spectrophotometry; Tumor Cells, Cultured

1998
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-29, Volume: 95, Issue:20

    Topics: Adenosine Triphosphate; Antioxidants; Azoles; Cell Hypoxia; Cell Line; Cobalt; DNA-Binding Proteins; DNA, Mitochondrial; Endothelial Growth Factors; Erythropoietin; Glycolysis; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Isoindoles; Lymphokines; Mitochondria, Liver; Nuclear Proteins; Organoselenium Compounds; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Transcription Factors; Transcriptional Activation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity.
    Molecular pharmacology, 1998, Volume: 54, Issue:5

    Topics: Animals; Antimutagenic Agents; Base Sequence; Cell Hypoxia; Chelating Agents; Cobalt; Deferoxamine; DNA; DNA-Binding Proteins; Endothelial Growth Factors; Enzyme Inhibitors; Erythropoietin; Fibroblasts; Gene Expression Regulation, Neoplastic; Hepatoblastoma; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Lymphokines; Mersalyl; Nuclear Proteins; Phosphopyruvate Hydratase; Rats; Receptor, IGF Type 1; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Optimal erythropoietin expression in human hepatoma cell lines requires activation of multiple signalling pathways.
    International journal of molecular medicine, 1998, Volume: 2, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Count; Cell Hypoxia; Cobalt; Dexamethasone; Erythropoietin; Humans; Interleukin-6; Liver Neoplasms; Oxygen; Signal Transduction

1998
Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling.
    The Journal of biological chemistry, 1999, Mar-26, Volume: 274, Issue:13

    Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Carbon Monoxide; Cell Hypoxia; Cell Line; Cobalt; Cyclic GMP; Cysteine; Deferoxamine; DNA-Binding Proteins; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Nitric Oxide; Nitroprusside; Nuclear Proteins; Oxygen; Receptors, Aryl Hydrocarbon; RNA, Messenger; Transcription Factors; Transcriptional Activation; Transfection

1999
Erythropoietin is produced by tubular cells of the rat kidney.
    Cell biochemistry and biophysics, 1999, Volume: 30, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Antimutagenic Agents; Blotting, Southern; Cobalt; Erythropoietin; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Exchanging ATPase

1999
Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation.
    The Journal of biological chemistry, 1999, Apr-23, Volume: 274, Issue:17

    Topics: Base Sequence; Binding, Competitive; Cobalt; Cytochrome P-450 CYP1A1; Dioxins; DNA; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Promoter Regions, Genetic; Receptor Cross-Talk; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Transcription Factors; Tumor Cells, Cultured

1999
Erythropoietin production: evidence for multiple oxygen sensing pathways.
    Annals of hematology, 1999, Volume: 78, Issue:6

    Topics: Chelating Agents; Cobalt; Deferoxamine; Erythropoietin; Humans; Iron Chelating Agents; Oxygen; Partial Pressure; Reactive Oxygen Species; Sulfhydryl Reagents; Tumor Cells, Cultured

1999
Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and ery
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Nov-15, Volume: 19, Issue:22

    Topics: Activating Transcription Factor 1; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Chelating Agents; Cobalt; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Deferoxamine; DNA-Binding Proteins; Enzyme Induction; Erythropoietin; Fetus; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Glutathione; Glycolysis; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; L-Lactate Dehydrogenase; Mimosine; Neurons; Neuroprotective Agents; Nuclear Proteins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transcription Factors

1999
A new biological strategy for high productivity of recombinant proteins in animal cells by the use of hypoxia-response enhancer.
    Biotechnology and bioengineering, 2000, Jan-20, Volume: 67, Issue:2

    Topics: Animals; Base Sequence; Carbohydrates; Cell Hypoxia; CHO Cells; Cobalt; Cricetinae; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythropoietin; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Sequence Data; Nuclear Proteins; Oxygen; Promoter Regions, Genetic; Protein Engineering; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2000
Cadmium and platinum suppression of erythropoietin production in cell culture: clinical implications.
    Blood, 2000, Dec-01, Volume: 96, Issue:12

    Topics: Cadmium; Cell Survival; Cisplatin; Cobalt; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Environmental Exposure; Erythropoietin; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mercury; Metals, Heavy; Nuclear Proteins; Protein Binding; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; Zinc

2000
Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:9

    Topics: Animals; Animals, Newborn; Blotting, Northern; Brain; Cobalt; DNA-Binding Proteins; Erythropoietin; Female; Fructose-Bisphosphate Aldolase; Gene Expression; Glucose Transporter Type 1; Glycolysis; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Ischemic Preconditioning; L-Lactate Dehydrogenase; Male; Monosaccharide Transport Proteins; Nuclear Proteins; Phosphofructokinase-1; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factors

2001
Cardiac function, microvascular structure, and capillary hematocrit in hearts of polycythemic rats.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:6

    Topics: Animals; Arterioles; Capillaries; Cobalt; Coronary Circulation; Erythropoietin; Hematocrit; Male; Microcirculation; Neovascularization, Pathologic; Polycythemia; Rats; Rats, Sprague-Dawley; Ventricular Function, Left

2001
Contribution of quinolinic acid in the development of anemia in renal insufficiency.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:4

    Topics: Anemia; Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Survival; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoiesis; Erythropoietin; Humans; Kidney Failure, Chronic; Male; Neurotoxins; Organ Specificity; Quinolinic Acid; Rats; Rats, Wistar; RNA, Messenger; Tumor Cells, Cultured

2003
Studies on erythropoiesis. V. The effect of cobalt on the production of erythropoietin.
    Blood, 1958, Volume: 13, Issue:1

    Topics: Cobalt; Epoetin Alfa; Erythrocytes; Erythropoiesis; Erythropoietin; Humans

1958
Presence of an active erythropoietic factor (erythropoietin) in plasma of rats after prolonged cobalt therapy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 99, Issue:2

    Topics: Animals; Cobalt; Epoetin Alfa; Erythrocytes; Erythropoietin; Health Services; Plasma; Rats

1958
Effect of adrenalectomy on the erythropoietic response to sheep erythropoietin and cobalt.
    Endocrinology, 1962, Volume: 70

    Topics: Adrenalectomy; Animals; Cobalt; Epoetin Alfa; Erythropoietin; Hematopoietic System; Sheep; Sheep, Domestic

1962
Relation between erythropoietin plasma level and oxygen requirements.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 112

    Topics: Anemia; Biological Assay; Cobalt; Epoetin Alfa; Erythropoietin; Humans; Hypophysectomy; Hypoxia; Oxygen; Starvation

1963
The influence of cobalt and sheep erythropoietin on radioactive iron incorporation in RBC of starved intact and nephrectomized rats.
    Blood, 1963, Volume: 21

    Topics: Animals; Cobalt; Epoetin Alfa; Erythrocytes; Erythropoietin; Iron; Nephrectomy; Rats; Sheep; Starvation

1963
INFLUENCE OF COBALT, SHEEP ERYTHROPOIETIN AND SEVERAL HORMONES ON ERYTHROPOIESIS IN BONE MARROWS OF ISOLATED PERFUSED HIND LIMBS OF DOGS.
    Blood, 1964, Volume: 23

    Topics: Animals; Bone Marrow; Chemotherapy, Cancer, Regional Perfusion; Cobalt; Dogs; Epoetin Alfa; Erythrocytes; Erythropoiesis; Erythropoietin; Femur; Growth Hormone; Human Growth Hormone; Hydrocortisone; Iron Isotopes; Research; Sheep; Testosterone; Triiodothyronine

1964
INFLUENCE OF X-IRRADIATION OF THE DOG KIDNEY ON ERYTHROPOIETIN PRODUCTION.
    Acta haematologica, 1964, Volume: 31

    Topics: Blood Chemical Analysis; Blood Pressure; Cobalt; Creatine; Creatinine; Dogs; Epoetin Alfa; Erythropoiesis; Erythropoietin; Iron Isotopes; Kidney; Kidney Function Tests; Nephrectomy; Nitrogen; Radiation Effects; Research; Urea

1964
[STUDIES ON ERYTHROPOIETIN. INVESTIGATIONS ON ERYTHROPOIETIC ACTION OF SEVERAL HORMONES FROM THE POINT OF VIEW OF THEIR CALORIGENICITIES].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1964, Volume: 27

    Topics: Adrenocorticotropic Hormone; Basal Metabolism; Cobalt; Cortisone; Epoetin Alfa; Erythropoietin; Hormones; Hypophysectomy; Pharmacology; Physiology; Pituitary Hormones, Anterior; Rats; Research; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine

1964
THE EFFECT OF ANAEMIA AND COBALT ON LACTIC DEHYDROGENASE ISOENZYMES IN KIDNEY TISSUES OF RABBITS AND ITS POSSIBLE RELATION TO THE ERYTHROPOIETIN PRODUCTION.
    Acta pathologica et microbiologica Scandinavica, 1965, Volume: 63

    Topics: Anemia; Animals; Blood Chemical Analysis; Cobalt; Electrophoresis; Enzymes; Epoetin Alfa; Erythropoietin; Iron Isotopes; Isoenzymes; Kidney; L-Lactate Dehydrogenase; Lagomorpha; Metabolism; Oxygen; Pharmacology; Rabbits; Research

1965
Erythropoietin. I. Analysis of radioiron assay in fasted rats, using cobalt as a reference standard.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 103

    Topics: Animals; Biological Assay; Cobalt; Epoetin Alfa; Erythrocytes; Erythropoietin; Fasting; Protein Binding; Rats

1960
Bisphenol A, an environmental endocrine-disrupting chemical, inhibits hypoxic response via degradation of hypoxia-inducible factor 1alpha (HIF-1alpha): structural requirement of bisphenol A for degradation of HIF-1alpha.
    Biochemical and biophysical research communications, 2004, Jun-11, Volume: 318, Issue:4

    Topics: Air Pollutants, Occupational; Benzhydryl Compounds; Cell Hypoxia; Cell Line, Tumor; Cobalt; Erythropoietin; Estrogens, Non-Steroidal; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Phenols; Precipitin Tests; Structure-Activity Relationship; Transcription Factors

2004
Apigenin suppresses the expression of VEGF, an important factor for angiogenesis, in endothelial cells via degradation of HIF-1alpha protein.
    FEBS letters, 2004, Sep-24, Volume: 575, Issue:1-3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apigenin; Cell Line; Cobalt; Endothelial Cells; Endothelium, Vascular; Erythropoietin; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Transcription Factors; Vascular Endothelial Growth Factor A

2004
Functional erythropoietin autocrine loop in melanoma.
    The American journal of pathology, 2005, Volume: 166, Issue:3

    Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cobalt; Coloring Agents; Culture Media, Conditioned; Disease Progression; Dose-Response Relationship, Drug; Erythropoietin; Humans; Hypoxia; Immunohistochemistry; MAP Kinase Signaling System; Melanocytes; Melanoma; Membrane Potentials; Mitochondria; Phosphorylation; Receptors, Erythropoietin; Tetrazolium Salts; Thiazoles; Trypan Blue

2005
Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis.
    Kidney international, 2005, Volume: 68, Issue:6

    Topics: Animals; Antibodies; Antimutagenic Agents; Apoptosis; Capillaries; Cobalt; Erythropoietin; Gene Expression Regulation; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Heme Oxygenase-1; Hypoxia; Hypoxia-Inducible Factor 1; In Situ Nick-End Labeling; Isoantibodies; Kidney Tubules; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Reperfusion Injury; Vascular Endothelial Growth Factor A

2005
Erythropoietin in thyroid cancer.
    Journal of endocrinological investigation, 2006, Volume: 29, Issue:4

    Topics: Carrier Proteins; Caseins; Cathepsin D; Cell Line, Tumor; Cobalt; Cyclooxygenase 2; Erythropoietin; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Receptors, Erythropoietin; RNA-Binding Proteins; RNA, Messenger; Thyroid Neoplasms; Tumor Suppressor Protein p53

2006
Cobalt supplementation promotes hypoxic tolerance and facilitates acclimatization to hypobaric hypoxia in rat brain.
    High altitude medicine & biology, 2008,Spring, Volume: 9, Issue:1

    Topics: Acclimatization; Adaptation, Physiological; Altitude Sickness; Animals; Cobalt; Erythropoietin; Glucose Transporter Type 1; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Species Specificity; Vascular Endothelial Growth Factor A

2008
Heterogeneity in binding and gene-expression regulation by HIF-2alpha.
    Biochemical and biophysical research communications, 2008, Jun-27, Volume: 371, Issue:2

    Topics: Anaerobiosis; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cobalt; Erythropoietin; Gene Expression; Gene Expression Regulation; Humans; Oxygen; Promoter Regions, Genetic; Transcriptional Activation

2008
Hypoxic preconditioning facilitates acclimatization to hypobaric hypoxia in rat heart.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:12

    Topics: Acclimatization; Animals; Cardiotonic Agents; Cobalt; DNA-Binding Proteins; Erythropoietin; Heart; Heme Oxygenase-1; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Metallothionein; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Up-Regulation; Vascular Endothelial Growth Factor A

2010
Recovery of motor spontaneous activity after intranasal delivery of human recombinant erythropoietin in a focal brain hypoxia model induced by CoCl2 in rats.
    Neurotoxicity research, 2011, Volume: 20, Issue:2

    Topics: Administration, Intranasal; Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cobalt; Disease Models, Animal; Erythropoietin; Exploratory Behavior; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Erythropoietin; Recombinant Proteins; Recovery of Function; Reticulocytes; Rotarod Performance Test

2011
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner.
    Laboratory investigation; a journal of technical methods and pathology, 2011, Volume: 91, Issue:11

    Topics: Animals; Blotting, Western; Cobalt; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Gene Expression Regulation; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1; Indican; Indoles; Kidney Failure, Chronic; Luciferases; Oxygen; Rats; Uremia

2011
Bone marrow-derived mesenchymal stem cells prevent the apoptosis of neuron-like PC12 cells via erythropoietin expression.
    Neuroscience letters, 2012, Aug-01, Volume: 522, Issue:2

    Topics: Animals; Apoptosis; Bone Marrow Cells; Caspases; Cell Hypoxia; Cells, Cultured; Cobalt; Cytoprotection; Erythropoietin; Gene Knockdown Techniques; Male; Mesenchymal Stem Cells; Neurons; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Up-Regulation

2012
Endoplasmic reticulum stress signal impairs erythropoietin production: a role for ATF4.
    American journal of physiology. Cell physiology, 2013, Feb-15, Volume: 304, Issue:4

    Topics: 3' Untranslated Regions; Activating Transcription Factor 4; Animals; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Cell Hypoxia; Cell Nucleus; Cobalt; Endoplasmic Reticulum Stress; Enhancer Elements, Genetic; Erythropoietin; Hep G2 Cells; Humans; Kidney; Liver; Male; Protein Binding; Protein Transport; Rats; Rats, Wistar; Transcription, Genetic; Transcriptional Activation; Unfolded Protein Response

2013
Protective action of erythropoietin on neuronal damage induced by activated microglia.
    The FEBS journal, 2013, Volume: 280, Issue:7

    Topics: Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Cobalt; Culture Media, Conditioned; Erythropoietin; Humans; Inflammation; Mice; Microglia; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide Synthase Type II; Nitrites; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Receptors, Erythropoietin; Tumor Necrosis Factor-alpha

2013
The role of HIF in cobalt-induced ischemic tolerance.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: Amino Acids, Dicarboxylic; Animals; Astrocytes; Brain Ischemia; Cell Survival; Cells, Cultured; Cobalt; Deferoxamine; Erythropoietin; Hippocampus; Hypoxia-Inducible Factor 1; Immunohistochemistry; Ischemic Preconditioning; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Polymerase Chain Reaction; Prolyl-Hydroxylase Inhibitors

2013
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:11

    Topics: Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cobalt; Deferoxamine; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Phosphoglycerate Kinase; Promoter Regions, Genetic; Propanolamines; Protein Binding; Pyrrolidines; RNA, Messenger; Superoxide Dismutase; Transcription, Genetic; Upstream Stimulatory Factors

2013
SOME PROPERTIES OF SERUM FROM RABBITS IMMUNIZED WITH HUMAN URINARY ERYTHROPOIETIN. UCRL-11184.
    UCRL [reports]. U.S. Atomic Energy Commission, 1963,Fall, Volume: 72

    Topics: Adrenocorticotropic Hormone; Animals; Antigen-Antibody Reactions; Ceruloplasmin; Cobalt; Epoetin Alfa; Erythropoiesis; Erythropoietin; Freund's Adjuvant; gamma-Globulins; Hematocrit; Hydrocortisone; Immune Sera; Immunization; Iron; Iron Isotopes; Mice; Mucoproteins; Neuraminic Acids; Neutralization Tests; Phenylhydrazines; Polycythemia; Rabbits; Research; Thyroxine; Transferrin; Urine

1963
The effects of CoCl2 on HIF-1α protein under experimental conditions of autoprogressive hypoxia using mouse models.
    International journal of molecular sciences, 2014, Jun-18, Volume: 15, Issue:6

    Topics: Animals; Cobalt; DNA; Erythropoietin; Hippocampus; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Models, Animal; Protein Binding; RNA, Messenger; Vascular Endothelial Growth Factor A

2014
Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice.
    Scientific reports, 2018, 10-02, Volume: 8, Issue:1

    Topics: Adenine; Animals; Autophagosomes; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Chromones; Cobalt; Disease Models, Animal; Erythropoietin; Humans; Liver; Liver Function Tests; Mice; Mice, Inbred C57BL; Morpholines; Peptide Fragments; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2018
Analysis of cobalt for human sports drug testing purposes using ICP- and LC-ICP-MS.
    Drug testing and analysis, 2020, Volume: 12, Issue:11-12

    Topics: Adult; Chromatography, Liquid; Cobalt; Doping in Sports; Erythropoietin; Female; Humans; Male; Mass Spectrometry; Middle Aged; Substance Abuse Detection; Tandem Mass Spectrometry; Vitamin B 12; Young Adult

2020