cobalt has been researched along with acetylcysteine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.12) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 16 (48.48) | 24.3611 |
| 2020's | 4 (12.12) | 2.80 |
| Authors | Studies |
|---|---|
| Mitchell, JR; Timbrell, JA | 1 |
| Corbella, J; Domingo, JL; Llobet, JM | 2 |
| Domingo, JL; Llobet, JM; Tomás, JM | 1 |
| Faller, DV; Phelan, MW | 1 |
| Gräslund, A; Karlberg, AT; Nilsson, JL; Scheynius, A; Van den Broeke, LT; Wahlberg, JE | 1 |
| Chandel, NS; Schumacker, PT; Thompson, CB; Vander Heiden, MG | 1 |
| Choi, Y; Chung, WJ; Kim, HH; Kim, MS; Kim, SW; Kwack, K; Lee, SE; Lee, ZH; Park, H | 1 |
| Hebert, C; Nikitakis, NG; Norris, K; Sauk, JJ; Siavash, H; Stewart, J | 1 |
| Wang, H; Xu, H; Yang, X; Zhang, Z | 1 |
| Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G | 1 |
| Bockmühl, U; Fuchs, J; Gross, J; Jahnke, V; Kietzmann, T; Machulik, A | 1 |
| Giles, GI; Gillespie, GY; Griguer, CE; Kelley, EE; Lancaster, JR; Oliva, CR | 1 |
| Chen, JK; Tzeng, SF; Yang, CS; Zhan, YJ | 1 |
| Adachi, T; Aida, K; Hara, H; Kamiya, T; Nishihara, H | 1 |
| Chen, P; Feng, J; Hu, F; Lan, A; Liao, X; Mo, L; Wang, X; Xiao, L; Yang, C; Yang, Z; Zheng, D | 1 |
| Lynch, C; Patel, E; Reynolds, M; Ruff, V | 1 |
| Hashemi, HS; Nezamzadeh-Ejhieh, A | 1 |
| Chien, S; Feng, L; Mo, Y; Tollerud, DJ; Wan, R; Zhang, Q | 1 |
| Chen, H; Cui, Y; Fan, X; Feng, X; Gu, P; Qi, H; Tan, P; Yang, L; Zheng, J; Zhou, W; Zhu, L; Zhu, X | 1 |
| Czyzyk-Krzeska, M; Gozal, D; Kawedia, JD; Menon, AG; Sartor, MA; Yang, F | 1 |
| Bian, W; Dong, C; Li, Y; Liu, Q; Ma, J; Shuang, S; Wei, Y | 1 |
| Luczak, MW; Zhitkovich, A | 1 |
| Cai, D; Li, S; Li, X; Li, Y; Liao, X; Lin, Y; Liu, G; Pan, B; Wang, H; Zhu, L | 1 |
| Chattopadhyay, S; Das, B; Dash, SK; Mandal, D; Pramanik, P; Roy, S; Tripathy, S | 1 |
| Bian, W; Choi, MM; Dong, W; Liu, Q; Shuang, S; Wang, F; Wang, L; Wei, Y | 1 |
| Chattopadhyay, S; Das, B; Dash, SK; Kar Mahapatra, S; Pramanik, P; Roy, S; Tripathy, S | 1 |
| Ahamed, M; Akhtar, MJ; Alhadlaq, HA; Alshamsan, A | 1 |
| Liu, F; Liu, YK; Wang, MH; Wang, W; Yang, HL; Yang, HW | 1 |
| Grulli, F; Locatelli, CA; Lonati, D; Perotti, F; Ronchi, A; Spinillo, A | 1 |
| Ge, X; He, C; Huang, C; Liu, S; Yang, C; Yang, S; Zhang, X | 1 |
| Lach, K; Pelclova, D | 1 |
| Carnovale, M; Locatelli, CA; Lonati, D; Petrolini, VM; Schicchi, A | 1 |
33 other study(ies) available for cobalt and acetylcysteine
| Article | Year |
|---|---|
Toxicity-related changes in benzene metabolism in vivo.
Topics: Acetylcysteine; Animals; Benzene; Breath Tests; Cobalt; Male; Phenobarbital; Phenols; Piperonyl Butoxide; Rats | 1977 |
Comparative effects of repeated parenteral administration of several chelators on the distribution and excretion of cobalt.
Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Edetic Acid; Glutathione; Injections, Intraperitoneal; Male; Pentetic Acid; Rats; Rats, Inbred Strains; Succimer | 1988 |
Comparison of the effectiveness of several chelators after single administration on the toxicity, excretion and distribution of cobalt.
Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Cysteine; Edetic Acid; Glutathione; Male; Mice; Pentetic Acid; Tissue Distribution | 1986 |
N-acetyl-L-cysteine in acute cobalt poisoning.
Topics: Acetylcysteine; Animals; Cobalt; Male; Rats; Rats, Inbred Strains | 1985 |
Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells.
Topics: Acetylcysteine; Animals; Bradykinin; Cattle; Cell Hypoxia; Cells, Cultured; Cobalt; Dactinomycin; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Nitric Oxide Synthase; Oxygen; Proline; Protein Precursors; RNA, Messenger; Suppression, Genetic; Thiocarbamates; Umbilical Veins | 1996 |
Free radicals as potential mediators of metal-allergy: Ni2+- and Co2+-mediated free radical generation.
Topics: Acetylcysteine; Adult; Ascorbic Acid; Carnosine; Cells, Cultured; Cobalt; Cysteine; Dermatitis, Allergic Contact; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Glutathione; Histidine; Humans; Hydrogen Peroxide; Middle Aged; Monocytes; Nickel | 1998 |
Redox regulation of p53 during hypoxia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcysteine; Animals; Antioxidants; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Death; Cell Division; Cell Hypoxia; Cells, Cultured; Chick Embryo; Cobalt; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ditiocarb; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Mice; Mitochondria; Myocardium; Reactive Oxygen Species; Rotenone; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uncoupling Agents | 2000 |
Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells.
Topics: Acetylcysteine; Blotting, Western; Calcitriol; Cell Line; Cobalt; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Free Radical Scavengers; Gene Expression; Glucocorticoids; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Lymphokines; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Phenotypic switching of VEGF and collagen XVIII during hypoxia in head and neck squamous carcinoma cells.
Topics: Acetylcysteine; Androstadienes; Antimutagenic Agents; Biomarkers; Cell Hypoxia; Cell Line, Tumor; Cobalt; Collagen Type XVIII; Enzyme Inhibitors; Head and Neck Neoplasms; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Humans; Imidazoles; MAP Kinase Signaling System; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Vascular Endothelial Growth Factor A; Wortmannin | 2003 |
Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.
Topics: Acetylcysteine; Aniline Compounds; Apoptosis; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; Cell Line, Tumor; Cell Size; Cell Survival; Cobalt; Colonic Neoplasms; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Fluoresceins; Glutathione; Humans; Membrane Potentials; Mitochondria; Reactive Oxygen Species; Ruthenium Red; Sodium Selenite; Xanthenes | 2003 |
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin | 2004 |
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cell Shape; Cobalt; Deferoxamine; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Necrosis; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors | 2005 |
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells.
Topics: Acetylcysteine; Cell Line, Tumor; Cobalt; Free Radicals; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Xanthine Oxidase | 2006 |
Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes.
Topics: Acetylcysteine; Animals; Astrocytes; Cells, Cultured; Cobalt; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Reactive Oxygen Species; RNA, Messenger; Thrombospondin 1 | 2011 |
Effect of hypoxia mimetic cobalt chloride on the expression of extracellular-superoxide dismutase in retinal pericytes.
Topics: Acetylcysteine; Animals; Apoptosis; Butyric Acid; Caspase 3; Cobalt; Diabetic Retinopathy; DNA Fragmentation; Down-Regulation; Free Radical Scavengers; Hypoxia; Pericytes; Rats; Reactive Oxygen Species; Retina; Superoxide Dismutase | 2011 |
Hydrogen sulfide protects against chemical hypoxia-induced injury by inhibiting ROS-activated ERK1/2 and p38MAPK signaling pathways in PC12 cells.
Topics: Acetylcysteine; Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cobalt; Cystathionine beta-Synthase; Down-Regulation; Enzyme Activation; Hydrogen Sulfide; Hypoxia-Inducible Factor 1, alpha Subunit; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Rats; Reactive Oxygen Species; Up-Regulation | 2011 |
Co-exposure to nickel and cobalt chloride enhances cytotoxicity and oxidative stress in human lung epithelial cells.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspase 7; Cell Survival; Cells, Cultured; Cobalt; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Lung; Nickel; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species | 2012 |
Voltammetric determination of cysteine using carbon paste electrode modified with Co(II)-Y zeolite.
Topics: Acetylcysteine; Carbon; Cobalt; Cysteine; Electrochemistry; Electrodes; Humans; Hydrogen-Ion Concentration; Limit of Detection; Oxidation-Reduction; Reproducibility of Results; Tablets; Zeolites | 2012 |
DNA damage caused by metal nanoparticles: involvement of oxidative stress and activation of ATM.
Topics: Acetylcysteine; Ataxia Telangiectasia Mutated Proteins; Catalase; Cell Cycle Proteins; Cell Line, Tumor; Cobalt; DNA; DNA Damage; DNA-Binding Proteins; Histones; Humans; Metal Nanoparticles; Morpholines; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Pyrones; Rad51 Recombinase; Reactive Oxygen Species; Titanium; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
N-acetylcysteine protects against hypoxia mimetic-induced autophagy by targeting the HIF-1α pathway in retinal ganglion cells.
Topics: Acetylcysteine; Animals; Animals, Newborn; Autophagy; Cell Hypoxia; Cell Line; Cell Line, Transformed; Cell Survival; Cobalt; Dose-Response Relationship, Drug; Drug Delivery Systems; Hypoxia-Inducible Factor 1, alpha Subunit; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retinal Ganglion Cells | 2012 |
Hypoxia and hypoxia mimetics decrease aquaporin 5 (AQP5) expression through both hypoxia inducible factor-1α and proteasome-mediated pathways.
Topics: Acetylcysteine; Animals; Aquaporin 5; Cell Hypoxia; Cell Line; Cobalt; Epithelial Cells; Gene Expression; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Mice; Oxygen; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Respiratory Mucosa; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Water | 2013 |
A novel phosphorescence sensor for Co2+ ion based on Mn-doped ZnS quantum dots.
Topics: Acetylcysteine; Cobalt; Ions; Luminescent Agents; Luminescent Measurements; Manganese; Quantum Dots; Sulfides; Zinc Compounds | 2014 |
Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II).
Topics: Acetylcysteine; Antioxidants; Blotting, Western; Cadmium; Cell Line; Chromium; Cobalt; Cytoprotection; Humans; Oxidative Stress | 2013 |
H2S inhibition of chemical hypoxia-induced proliferation of HPASMCs is mediated by the upregulation of COX-2/PGI2.
Topics: Acetylcysteine; Cell Hypoxia; Cell Line; Cell Proliferation; Cobalt; Cyclooxygenase 2; Down-Regulation; Epoprostenol; Familial Primary Pulmonary Hypertension; Humans; Hydrogen Peroxide; Hydrogen Sulfide; Hypertension, Pulmonary; Myocytes, Smooth Muscle; Oxidative Stress; Pulmonary Artery; Reactive Oxygen Species; Sulfides | 2014 |
Toxicity of cobalt oxide nanoparticles to normal cells; an in vitro and in vivo study.
Topics: Acetylcysteine; Animals; Apoptosis; Biological Transport; Biomarkers; Cobalt; Cytokines; Hemolysis; Humans; Mice; Nanoparticles; Oxidative Stress; Oxides; Reactive Oxygen Species; Toxicity Tests | 2015 |
Doped zinc sulfide quantum dots based phosphorescence turn-off/on probe for detecting histidine in biological fluid.
Topics: Acetylcysteine; Adsorption; Adult; Cobalt; Histidine; Humans; Hydrogen-Ion Concentration; Limit of Detection; Luminescent Agents; Luminescent Measurements; Manganese; Quantum Dots; Sulfides; Time Factors; Urinalysis; Zinc Compounds | 2015 |
Cobalt oxide nanoparticles induced oxidative stress linked to activation of TNF-α/caspase-8/p38-MAPK signaling in human leukemia cells.
Topics: Acetylcysteine; Animals; Apoptosis; Caspase 8; Cell Death; Cell Line, Tumor; Cobalt; Humans; Leukemia, Experimental; MAP Kinase Signaling System; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Neoplasm Transplantation; Oxidative Stress; Oxides; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Tumor Necrosis Factor-alpha | 2015 |
Nanotoxicity of cobalt induced by oxidant generation and glutathione depletion in MCF-7 cells.
Topics: Acetylcysteine; Antioxidants; Buthionine Sulfoximine; Caspase 3; Cell Survival; Cobalt; Glutathione; Humans; Lipid Peroxidation; MCF-7 Cells; Membrane Potential, Mitochondrial; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Oxidative Stress; Reactive Oxygen Species; Solubility; X-Ray Diffraction | 2017 |
N-acetylcysteine Attenuates Cobalt Nanoparticle-Induced Cytotoxic Effects through Inhibition of Cell Death, Reactive Oxygen Species-related Signaling and Cytokines Expression.
Topics: Acetylcysteine; Animals; Apoptosis; Biomarkers; Blotting, Western; Cell Line; Cobalt; Cytokines; Free Radical Scavengers; Hip Prosthesis; Metal-on-Metal Joint Prostheses; Mice; Nanoparticles; Reactive Oxygen Species; Signal Transduction | 2016 |
Management of high concentrations of cobalt and chromium in blood due to metal-on-metal hip arthroplasty in a pregnant woman.
Topics: Abortion, Spontaneous; Acetylcysteine; Adult; Arthroplasty, Replacement, Hip; Chelating Agents; Chromium; Cobalt; Female; Hip Prosthesis; Humans; Live Birth; Maternal Age; Metal-on-Metal Joint Prostheses; Middle Aged; Pregnancy; Pregnancy Complications; Prosthesis Design; Risk Factors; Treatment Outcome; Up-Regulation | 2021 |
N-Acetylcysteine protects against cobalt chloride-induced endothelial dysfunction by enhancing glucose-6-phosphate dehydrogenase activity.
Topics: Acetylcysteine; Cobalt; Glucosephosphate Dehydrogenase; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Vascular Diseases | 2022 |
Efficacy of unithiol (2,3-dimercaptopropanesulfonate) and acetylcysteine in a patient with arthroplastic cobalt toxicity.
Topics: Acetylcysteine; Antidotes; Cobalt; Humans; Unithiol | 2023 |
Reply to "Efficacy of unithiol (2,3-dimercaptopropanesulfonate) and acetylcysteine in a patient with arthroplastic cobalt toxicity".
Topics: Acetylcysteine; Antidotes; Cobalt; Humans; Unithiol | 2023 |