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cobalt and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

cobalt has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, RT; Chiang, GG; Giaccia, AJ; Hudson, CC; Kaper, F; Liu, M; Loomis, DC; Otterness, DM1
Choi, SM; Choi, Y; Chung, J; Lee, N; Park, H; Yim, S1
Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G1
Arnold, W; Giese, K; Kaufmann, J; Klippel, A; Schwarzer, R; Tondera, D1
Gonsalves, C; Johnson, C; Kalra, VK; Kim, KS; Rajagopal, V1
Brabant, G; Burrows, N; Cowen, RL; Hoang-Vu, C; Resch, J; von Wasielewski, R; West, CM; Williams, KJ1
Baek, JC; Choi, WS; Jeong, JW; Kang, MY; Lee, JH; Lee, SA; Paik, WY; Park, JK; Shin, JK1
Jeong, E; Joung, SM; Kim, SY; Lee, JY1
Mohamed, MAA; Park, SY; Sun, Z; Yi, TH1
Arai, K; Egawa, N; Ihara, M; Itoh, K; Liang, AC; Lo, EK; Lok, J; Maeda, M; Maki, T; Miyamoto, N; Shindo, A1
Endo, H; Ito, K; Nezu, T; Okada, C; Owada, S; Shida, Y; Tatemichi, M1
Chen, D; Chen, Z; Dai, C; Han, Z; He, F; Li, Y; Tan, R; Tian, H; Wang, G; Wang, M; Wei, L; Yang, B; Yang, H; Zhang, B1
Borin, TF; Carvalho, LGS; de Campos Zuccari, DAP; Ferreira, LC; Gelaleti, GB; Hellmén, E; Jardim-Perassi, BV; Leonel, C; Maschio-Signorini, LB; Moschetta, MG; Sonehara, NM1

Other Studies

13 other study(ies) available for cobalt and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
    Molecular and cellular biology, 2002, Volume: 22, Issue:20

    Topics: Cell Hypoxia; Chromones; Cobalt; DNA-Binding Proteins; Enzyme Inhibitors; Glucose Transporter Type 1; Helix-Loop-Helix Motifs; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Monosaccharide Transport Proteins; Morpholines; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; TOR Serine-Threonine Kinases; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

2002
Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Chromones; Cobalt; Dimerization; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genes, Dominant; Glutathione Transferase; Glycolysis; HeLa Cells; Humans; Hydrogen Peroxide; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Ligases; Luciferases; Mice; Molecular Sequence Data; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Pyrrolidines; Receptors, Aryl Hydrocarbon; RNA; Thiocarbamates; Time Factors; Transcription Factors; Transfection; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein

2003
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
    American journal of respiratory cell and molecular biology, 2004, Volume: 31, Issue:5

    Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin

2004
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
    Oncogene, 2005, Feb-10, Volume: 24, Issue:7

    Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Chromones; Cobalt; Dimethyl Sulfoxide; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; RNA, Antisense; Signal Transduction; Sirolimus; Transcription Factors; Up-Regulation

2005
A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-15, Volume: 177, Issue:10

    Topics: Base Sequence; Cell Line, Transformed; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Chromones; Cobalt; Endothelial Cells; Endothelium, Vascular; Flavonoids; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Imidazoles; Interleukin-8; Molecular Sequence Data; Morpholines; Protein Kinase Inhibitors; Pulmonary Artery; Pyridines; RNA, Messenger

2006
Expression of hypoxia-inducible factor 1 alpha in thyroid carcinomas.
    Endocrine-related cancer, 2010, Volume: 17, Issue:1

    Topics: Adenocarcinoma, Follicular; Anaerobiosis; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Carcinoma, Papillary; Cell Hypoxia; Cell Line, Tumor; Chromones; Cobalt; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; RNA Interference; RNA, Small Interfering; Signal Transduction; Thyroid Neoplasms

2010
Inhibition of the PI3K-Akt pathway suppresses sFlt1 expression in human placental hypoxia models in vitro.
    Placenta, 2010, Volume: 31, Issue:7

    Topics: Cell Line, Tumor; Cell Survival; Chromones; Cobalt; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Pregnancy Proteins; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2010
PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress.
    Biochemical and biophysical research communications, 2012, Mar-16, Volume: 419, Issue:3

    Topics: Animals; Cell Hypoxia; Cell Line; Chromones; Cobalt; Gene Knockdown Techniques; Hypoxia-Inducible Factor 1, alpha Subunit; Isothiocyanates; Macrophages; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger; Stress, Physiological; Sulfoxides; Thiocyanates; Toll-Like Receptor 4; Transcription, Genetic; Up-Regulation

2012
Fucosterol protects cobalt chloride induced inflammation by the inhibition of hypoxia-inducible factor through PI3K/Akt pathway.
    International immunopharmacology, 2015, Volume: 29, Issue:2

    Topics: Cell Line; Chromones; Cobalt; Cytokines; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Keratinocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Stigmasterol

2015
Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Oct-14, Volume: 35, Issue:41

    Topics: Animals; Antimutagenic Agents; Astrocytes; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Chromones; Cobalt; Culture Media, Conditioned; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione S-Transferase pi; Hypoxia-Inducible Factor 1, alpha Subunit; Leukoencephalopathies; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Myelin Basic Protein; Myelin Sheath; Phosphopyruvate Hydratase; Stem Cells

2015
Autophagy‑mediated adaptation of hepatocellular carcinoma cells to hypoxia‑mimicking conditions constitutes an attractive therapeutic target.
    Oncology reports, 2018, Volume: 39, Issue:4

    Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chromones; Cobalt; Gene Knockdown Techniques; Humans; Liver Neoplasms; Macrolides; Morpholines; Oxygen; Signal Transduction

2018
Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice.
    Scientific reports, 2018, 10-02, Volume: 8, Issue:1

    Topics: Adenine; Animals; Autophagosomes; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Chromones; Cobalt; Disease Models, Animal; Erythropoietin; Humans; Liver; Liver Function Tests; Mice; Mice, Inbred C57BL; Morpholines; Peptide Fragments; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2018
Evaluation of Angiogenesis Process after Metformin and LY294002 Treatment in Mammary Tumor.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:5

    Topics: Animals; Cell Line, Tumor; Chromones; Cobalt; Dog Diseases; Dogs; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Mammary Neoplasms, Animal; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Morpholines; Neovascularization, Pathologic; Oxygen; Vascular Endothelial Growth Factor A

2019