cnicin has been researched along with sesquiterpenes in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Vanhaelen, M; Vanhaelen-Fastré, R | 1 |
| Lachner, I; Schneider, G | 1 |
| Alvarez, M; Barrero, AF; Morales, V; Oltra, JE; Rodríguez-García, I | 1 |
| Bruno, M; Maggio, A; Napolitano, F; Raccuglia, RA; Rosselli, S; Senatore, F | 1 |
| Lax, A; Meepagala, KM; Osbrink, W; Sturtz, G | 1 |
| Bachelier, A; Klein, CD; Mayer, R | 1 |
| Klein, CD; Scheidig, AJ; Steinbach, A | 1 |
| Bastow, KF; Bruno, M; Lee, KH; Maggio, AM; Morris-Natschke, SL; Raccuglia, RA; Rosselli, S | 1 |
| Attarian, R; Av-Gay, Y; Bach, H; Bach, SM; Catalán, CA; de Trimarco, JT; Fortuna, MA | 1 |
| Bedir, E; Erel, SB; Glasl, S; Kaehlig, H; Karaalp, C; Khan, S; Krenn, L | 1 |
| Greil, R; Hamacher, F; Hermann, M; Jöhrer, K; Kern, J; Maizner, E; Merkel, O; Neureiter, D; Obkircher, M; Parteli, J; Scheideler, M; Wacht, N; Zelle-Rieser, C; Zidorn, C | 1 |
| Brandán, SA; Catalán, CA; Chain, FE; Fortuna, M; Leyton, P; Paipa, C; Romano, E | 1 |
| Andreadaki, A; Diekmann, H; Fischer, D; Gobrecht, P; Heskamp, A; Leibinger, M | 1 |
| Albayrak, G; Baykan, S; Demiroz, T; Gocmen, B; Nalbantsoy, A | 1 |
| Almeida, ADC; Coimbra, ES; Da Silva Filho, AA; de Moraes, J; Denadai, ÂML; Ferreira, EA; Mengarda, AC; Pinto, PF; Queiroz, LS | 1 |
15 other study(ies) available for cnicin and sesquiterpenes
| Article | Year |
|---|---|
[Antibiotic and cytotoxic activity of cnicin and of its hydrolysis products. Chemical structure - biological activity relationship (author's transl)].
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Chemical Phenomena; Chemistry; Hydrolysis; Lactones; Male; Mice; Microbial Sensitivity Tests; Sesquiterpenes | 1976 |
[Analysis and action of cnicin].
Topics: Animals; Anti-Inflammatory Agents; Lethal Dose 50; Male; Plants, Medicinal; Rats; Rats, Inbred Strains; Sesquiterpenes | 1987 |
Biomimetic cyclization of cnicin to malacitanolide, a cytotoxic eudesmanolide from Centaurea malacitana.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclization; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mice; Plant Leaves; Sesquiterpenes; Tumor Cells, Cultured | 1997 |
Antibacterial evaluation of cnicin and some natural and semisynthetic analogues.
Topics: Anti-Bacterial Agents; Centaurea; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Phytotherapy; Plant Preparations; Sesquiterpenes | 2003 |
Plant-derived natural products exhibiting activity against formosan subterranean termites (Coptotermes formosanus).
Topics: Animals; Artemisia; Centaurea; Chromatography, Gel; Dioxoles; Insecticides; Isoptera; Ligusticum; Plant Extracts; Sesquiterpenes | 2006 |
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.
Topics: Alkyl and Aryl Transferases; Enzyme Inhibitors; Escherichia coli; Lactones; Peptidoglycan; Pseudomonas aeruginosa; Sesquiterpenes; Structure-Activity Relationship | 2006 |
The unusual binding mode of cnicin to the antibacterial target enzyme MurA revealed by X-ray crystallography.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Sesquiterpenes; Uridine Diphosphate N-Acetylglucosamine | 2008 |
Acid rearrangment of epoxy-germacranolides and absolute configuration of 1beta,10alpha-epoxy-salonitenolide.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Centaurea; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Germacrane; Sicily | 2010 |
Antibacterial and cytotoxic activities of the sesquiterpene lactones cnicin and onopordopicrin.
Topics: Anti-Bacterial Agents; Cell Line; Cell Survival; Centaurea; Lactones; Methicillin-Resistant Staphylococcus aureus; Monocytes; Sesquiterpenes | 2011 |
Secondary metabolites of Centaurea calolepis and evaluation of cnicin for anti-inflammatory, antioxidant, and cytotoxic activities.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Cell Line; Cell Line, Tumor; Centaurea; Cytotoxins; Glycosides; Haplorhini; Humans; NF-kappa B; Nitric Oxide Synthase Type II; Phytotherapy; Plant Components, Aerial; Plant Extracts; Reactive Oxygen Species; Sesquiterpenes; Swine; Turkey | 2011 |
Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Humans; Microarray Analysis; Multiple Myeloma; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Sesquiterpenes | 2012 |
Vibrational and structural study of onopordopicrin based on the FTIR spectrum and DFT calculations.
Topics: Lactones; Models, Molecular; Molecular Conformation; Quantum Theory; Sesquiterpenes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Vibration | 2015 |
Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Axons; Dose-Response Relationship, Drug; Gene Knock-In Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Mice, Inbred C57BL; Microtubules; Nerve Regeneration; Nocodazole; Paclitaxel; Peripheral Nerves; Phosphorylation; Sciatic Nerve; Sesquiterpenes; Tyrosine | 2016 |
Anti-inflammatory properties of Centaurea calolepis Boiss. and cnicin against Macrovipera lebetina obtusa (Dwigubsky, 1832) and Montivipera xanthina (Gray, 1849) venoms in rat.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Centaurea; Edema; Female; Inflammation; Male; Mice; Plant Extracts; Rats, Wistar; Sesquiterpenes; Turkey; Viper Venoms; Viperidae | 2018 |
In vitro and in vivo evaluation of cnicin from blessed thistle (Centaurea benedicta) and its inclusion complexes with cyclodextrins against Schistosoma mansoni.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; Animals; beta-Cyclodextrins; Centaurea; Disease Models, Animal; Drug Compounding; Feces; Female; Injections, Intraperitoneal; Male; Mice; Parasite Egg Count; Parasite Load; Permeability; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Sesquiterpenes; Solubility | 2021 |