cm 7116 and flurazepam

cm 7116 has been researched along with flurazepam in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (72.22)	18.7374
1990's	2 (11.11)	18.2507
2000's	1 (5.56)	29.6817
2010's	2 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aoyama, T; Ichikawa, H; Suzuki, Y	1
Babbini, M; Barbaro, AM; Bartoletti, M; Biagi, GL; Borea, PA; Gaiardi, M; Guerra, MC	1
Battista, D; Hilbert, JM	1
Kauert, G; Klausnitzer, W; Schaffler, K; Wauschkuhn, CH	1
Namima, M; Sakai, Y	1
Bradbrook, I; Fazackerley, EJ; Mawer, GE; Pleuvry, BJ; Randall, NP	1
Ellinwood, EH; Gupta, SK	1
Aizawa, K; Fujita, M; Ito, M; Komiya, I; Miyagi, K; Umemura, K	1
Furukawa, T; Izawa, M; Kushiku, K; Morishita, H; Shibata, U; Shibazaki, Y; Yamaki, Y	1
Sieghart, W	1
Ikeda, K; Kiyota, Y; Ohta, H; Sato, Y; Shibata, K; Shibata, S; Ueki, S; Watanabe, S; Yamamoto, T	1
Gural, RP; Hilbert, JM; Symchowicz, S; Zampaglione, N	1
Chung, M; Gural, R; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N	1
Chung, M; Gural, RP; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N	1
Chung, M; Gural, R; Hilbert, JM; Maier, G; Symchowicz, S; Zampaglione, N	1
Aoshima, T; Fukasawa, T; Kanno, M; Kato, K; Otani, K; Suzuki, A; Yasui-Furukori, N	1
Ohno, Y; Yamaguchi, K; Zhou, J	1
Angerer, V; Auwärter, V; Bisel, P; Kempf, J; Moosmann, B; Westphal, F; Wilde, M	1

Reviews

2 review(s) available for cm 7116 and flurazepam

Article	Year
Neural networks applied to quantitative structure-activity relationship analysis. Journal of medicinal chemistry, 1990, Volume: 33, Issue:9 Topics: Animals; Azirines; Benzodiazepines; Carbazilquinone; Nerve Net; Nervous System; Regression Analysis; Structure-Activity Relationship	1990
Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics. The Journal of clinical psychiatry, 1991, Volume: 52 Suppl Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cricetinae; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Mice; Molecular Structure; Rats; Saimiri; Sleep Initiation and Maintenance Disorders; Tissue Distribution	1991

Trials

2 trial(s) available for cm 7116 and flurazepam

Article	Year
The respiratory effects of oral ethyl loflazepate in volunteers. British journal of clinical pharmacology, 1987, Volume: 23, Issue:2 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Female; Flurazepam; Hemodynamics; Humans; Male; Respiration; Respiratory Function Tests	1987
Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug. Therapeutic drug monitoring, 2003, Volume: 25, Issue:4 Topics: Administration, Oral; Adult; Area Under Curve; Benzodiazepines; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Itraconazole; Male; Psychomotor Performance; Sleep	2003

Article

Year

The respiratory effects of oral ethyl loflazepate in volunteers.

British journal of clinical pharmacology, 1987, Volume: 23, Issue:2

Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Female; Flurazepam; Hemodynamics; Humans; Male; Respiration; Respiratory Function Tests

1987

Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug.

Therapeutic drug monitoring, 2003, Volume: 25, Issue:4

Topics: Administration, Oral; Adult; Area Under Curve; Benzodiazepines; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Itraconazole; Male; Psychomotor Performance; Sleep

2003

Other Studies

14 other study(ies) available for cm 7116 and flurazepam

Article	Year
Rm values and structure-activity relationship of benzodiazepines. Journal of medicinal chemistry, 1980, Volume: 23, Issue:2 Topics: Animals; Benzodiazepines; Chromatography, Thin Layer; Conflict, Psychological; Exploratory Behavior; Models, Biological; Rats; Solubility; Structure-Activity Relationship	1980
Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam. Arzneimittel-Forschung, 1989, Volume: 39, Issue:2 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Electrooculography; Flurazepam; Hemodynamics; Humans; Male; Psychomotor Performance; Reaction Time; Respiration; Substance Withdrawal Syndrome	1989
Inhibitory effect on 3H-diazepam binding and potentiating action on GABA of ethyl loflazepate, a new minor tranquilizer. Japanese journal of pharmacology, 1985, Volume: 37, Issue:4 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Guinea Pigs; Male; Purkinje Cells	1985
Liquid chromatographic assay and pharmacokinetics of quazepam and its metabolites following sublingual administration of quazepam. Pharmaceutical research, 1988, Volume: 5, Issue:6 Topics: Administration, Sublingual; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Flurazepam; Humans; Male	1988
[Pharmacokinetics of the two major metabolites of ethyl loflazepate (CM6912) in dogs and humans. Simulation by a digital computer]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1986, Volume: 106, Issue:8 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Computer Simulation; Dogs; Flurazepam; Humans; Kinetics; Models, Biological	1986
[Pharmacological effects of CM6912 and its main metabolites]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1 Topics: Animals; Anti-Anxiety Agents; Autonomic Nervous System; Benzodiazepines; Benzodiazepinones; Cardiovascular System; Chemical Phenomena; Chemistry; Dogs; Female; Flurazepam; Guinea Pigs; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Neuromuscular Junction; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Respiration; Uterus	1985
Several new benzodiazepines selectively interact with a benzodiazepine receptor subtype. Neuroscience letters, 1983, Jul-15, Volume: 38, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebellum; Flunitrazepam; Flurazepam; Hippocampus; Membranes; Rats; Receptors, Cell Surface; Receptors, GABA-A	1983
[Behavioral effects of ethyl loflazepate and its metabolites]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 82, Issue:5 Topics: Aggression; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Conflict, Psychological; Diazepam; Drug Synergism; Flurazepam; Humans; Lorazepam; Male; Mice; Motor Activity; Nitrazepam; Rats; Rats, Inbred Strains; Thiopental	1983
Excretion of quazepam into human breast milk. Journal of clinical pharmacology, 1984, Volume: 24, Issue:10 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Female; Flurazepam; Humans; Milk, Human	1984
Quazepam kinetics in the elderly. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4 Topics: Absorption; Administration, Oral; Aged; Aging; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chromatography, Gas; Female; Flurazepam; Half-Life; Humans; Kinetics; Male	1984
Multiple-dose quazepam kinetics. Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:4 Topics: Absorption; Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Humans; Kinetics; Male	1984
Effect of sleep on quazepam kinetics. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1 Topics: Absorption; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Half-Life; Humans; Kinetics; Male; Random Allocation; Sleep; Time Factors	1984
Quantitative analysis of quazepam and its metabolites in human blood, urine, and bile by liquid chromatography-tandem mass spectrometry. Forensic science international, 2014, Volume: 241 Topics: Benzodiazepines; Benzodiazepinones; Bile; Chromatography, Liquid; Flurazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Male; Middle Aged; Molecular Structure; Tandem Mass Spectrometry	2014
Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines: An update comprising flunitrazolam, norflurazepam, and 4'-chlorodiazepam (Ro5-4864). Drug testing and analysis, 2019, Volume: 11, Issue:3 Topics: Benzodiazepines; Benzodiazepinones; Biotransformation; Chromatography, Liquid; Designer Drugs; Flurazepam; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Metabolic Detoxication, Phase I; Microsomes, Liver; Substance Abuse Detection; Tandem Mass Spectrometry	2019