clozapine and hydrazine

clozapine has been researched along with hydrazine* in 1 studies

Other Studies

1 other study(ies) available for clozapine and hydrazine

Article	Year
Hydrazides of clozapine: a new class of D1 dopamine receptor subtype selective antagonists. Bioorganic & medicinal chemistry letters, 2006, Sep-01, Volume: 16, Issue:17 Acylated and aroylated hydrazinoclozapines are highly potent dopamine D(1) antagonists that show remarkable selectivity over other dopamine receptors. The most potent compound in this series is the 2,6-dimethoxybenzhydrazide 33 with a D(1)K(i) of 1.6 nM and 212-fold selectivity over D(2) receptor. Topics: Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hydrazines; Molecular Structure; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship	2006

Article

Year

Hydrazides of clozapine: a new class of D1 dopamine receptor subtype selective antagonists.

Bioorganic & medicinal chemistry letters, 2006, Sep-01, Volume: 16, Issue:17

Acylated and aroylated hydrazinoclozapines are highly potent dopamine D(1) antagonists that show remarkable selectivity over other dopamine receptors. The most potent compound in this series is the 2,6-dimethoxybenzhydrazide 33 with a D(1)K(i) of 1.6 nM and 212-fold selectivity over D(2) receptor.

Topics: Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hydrazines; Molecular Structure; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship

2006