clotrimazole and voriconazole

clotrimazole has been researched along with voriconazole in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (22.22)29.6817
2010's18 (66.67)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Bergès, T; Bouchara, JP; Chabasse, D; Hennequin, C; Tronchin, G; Vandeputte, P1
Deising, HB; Serfling, A; Wohlrab, J1
Kelly, DE; Kelly, SL; Manning, NJ; Merkamm, M; Parker, JE; Pompon, D1
Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC; Marczylo, TH; Parker, JE; Warrilow, AG1
Bergès, T; Bouchara, JP; Chabasse, D; Renier, G; Rocher, F; Tronchin, G; Vandeputte, P1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Warrilow, AG; Weig, M1
Kelly, DE; Kelly, SL; Martel, CM; Melo, N; Nes, WD; Parker, JE; Warrilow, AG1
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M1
Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, NJ; Warrilow, AG1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Driscoll, MD; Lafite, P; Levy, C; Leys, D; Mast, N; McLean, KJ; Munro, AW; Pikuleva, IA; Rigby, SE1
Avery, VM; Sykes, ML1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Emami, S; Keighobadi, M; Tavangar, P1
Wang, SQ; Wang, YF; Xu, Z1
Benhamou, RI; Dorot, O; Elias, R; Fridman, M; Jaber, QZ; Oved, K; Pichinuk, E; Zada, SL1
Crego, AL; Gómez, J; Lavandera, JL; Marina, ML1
Charvet, C; Mast, N; Pikuleva, IA; Stout, CD1
Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG1
Mast, N; Pikuleva, IA; Stout, CD; Zheng, W1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG1
Holman, TR; Hughes, DD; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Rolley, NJ; Smyrniotis, CJ; Thoss, V; Warrilow, AG1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AGS; Wiederhold, NP1
Harada, K; Inagaki, K; Kampirapap, K; Koga, H; Maeda, J; Makimura, K; Nanjoh, Y; Neki, D; Reangchainam, S; Tsuboi, R; Yuasa, K1
Abou El-Alamin, MM; Aboul-Enein, HY; Atia, MA; Sultan, MA1
Abastabar, M; Aghili, SR; Badali, H; Haghani, I; Hedayati, MT; Javidnia, J; Khojasteh, S; Meis, JF; Moazeni, M; Nargesi, S; Nosratabadi, M; Shabanzadeh, S; Shokohi, T; Zaedi, A1

Reviews

4 review(s) available for clotrimazole and voriconazole

ArticleYear
Approaches to protozoan drug discovery: phenotypic screening.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2013
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: 14-alpha Demethylase Inhibitors; Antiprotozoal Agents; Azoles; Humans; Leishmania; Molecular Structure; Sterol 14-Demethylase

2017
Tetrazole hybrids and their antifungal activities.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antifungal Agents; Azoles; Fungi; Humans; Mycoses; Pyridines; Pyrimidines; Quinolines; Structure-Activity Relationship; Tetrazoles

2019

Other Studies

23 other study(ies) available for clotrimazole and voriconazole

ArticleYear
Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Antifungal Agents; Candida glabrata; Candidiasis; DNA Primers; Genes, Fungal; Genetic Complementation Test; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation, Missense; Phenotype; Polyenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal; RNA, Messenger; Sterols

2007
Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Amphotericin B; Antifungal Agents; Azoles; Caspofungin; Colletotrichum; Drug Resistance, Fungal; Drug Synergism; Echinocandins; Fungi; Fungicides, Industrial; Humans; In Vitro Techniques; Lipopeptides; Microbial Sensitivity Tests; Microscopy, Fluorescence; Nystatin; Plant Diseases; Skin; Triazoles

2007
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Antifungal Agents; Azoles; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Fungal; Drug Resistance, Fungal; Genes, Fungal; Humans; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Sterol 14-Demethylase

2008
Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Azoles; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mycobacterium leprae; Mycobacterium smegmatis; Osmolar Concentration; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride

2009
Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Adult; Aerobiosis; Antifungal Agents; Azoles; Candida glabrata; Chromatography, High Pressure Liquid; Ergosterol; Female; Flow Cytometry; Genes, Fungal; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular Sequence Data; Polyenes

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Drug Resistance, Fungal; Fungal Proteins; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction

2010
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Amino Acid Sequence; Aspergillus fumigatus; Azoles; Clotrimazole; Drug Resistance, Multiple, Fungal; Fluconazole; Fungal Proteins; Isoenzymes; Itraconazole; Lanosterol; Molecular Sequence Data; Protein Binding; Pyrimidines; Sequence Homology, Amino Acid; Sterol 14-Demethylase; Substrate Specificity; Triazoles; Voriconazole

2010
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole

2010
Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Aspergillus fumigatus; Azoles; Clotrimazole; Cytochrome P-450 Enzyme System; Doxycycline; Ergosterol; Fluconazole; Fungal Proteins; Genetic Complementation Test; Itraconazole; Pyrimidines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triazoles; Voriconazole

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
    The Journal of biological chemistry, 2010, Dec-03, Volume: 285, Issue:49

    Topics: Cholesterol; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Host-Pathogen Interactions; Humans; Hydroxylation; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Structure, Tertiary

2010
Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Antifungal Agents; Azoles; Candida; Cell Survival; Coumarins; Dose-Response Relationship, Drug; HEK293 Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Optical Imaging; Structure-Activity Relationship

2019
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.
    Electrophoresis, 2001, Volume: 22, Issue:12

    Topics: Acetic Acid; Acetonitriles; Antifungal Agents; Clotrimazole; Drug Stability; Electrophoresis, Capillary; Fluconazole; Humans; Itraconazole; Ketoconazole; Methanol; Microsomes, Liver; Molecular Structure; Molecular Weight; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Triazoles; Verapamil; Voriconazole

2001
Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain.
    The Journal of biological chemistry, 2010, Oct-08, Volume: 285, Issue:41

    Topics: Amino Acid Substitution; Anticonvulsants; Antidepressive Agents; Antifungal Agents; Brain; Catalytic Domain; Cholesterol; Cholesterol 24-Hydroxylase; Clotrimazole; Crystallography, X-Ray; Humans; Mutation, Missense; Piperidines; Protein Binding; Pyrimidines; Steroid Hydroxylases; Structure-Activity Relationship; Tranylcypromine; Triazoles; Voriconazole

2010
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole

2013
Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1.
    Molecular pharmacology, 2013, Volume: 84, Issue:1

    Topics: Antifungal Agents; Azoles; Binding Sites; Cholesterol; Cholesterol 24-Hydroxylase; Clotrimazole; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Humans; Protein Binding; Pyrimidines; Steroid Hydroxylases; Sterol 14-Demethylase; Triazoles; Voriconazole

2013
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole

2016
Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.
    Scientific reports, 2016, 06-13, Volume: 6

    Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Cytochrome P450 Family 51; Drug Evaluation, Preclinical; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Kinetics; Lipids; Malassezia; Spectrophotometry; Sterol 14-Demethylase; Sterols; Voriconazole

2016
The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7

    Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Substrate Specificity; Tetrazoles; Trichophyton; Voriconazole

2017
In vitro antifungal activity of luliconazole against nondermatophytic moulds.
    Medical mycology, 2020, Jul-01, Volume: 58, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Fluconazole; Fungi; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Morpholines; Sequence Analysis, DNA; Terbinafine; Triazoles; Voriconazole

2020
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
    Combinatorial chemistry & high throughput screening, 2020, Volume: 23, Issue:10

    Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Humans; Hydrocarbons, Brominated; Imidazoles; Ketoconazole; Liquid-Liquid Extraction; Molecular Structure; Thiophenes; Triazoles; Voriconazole

2020
In vitro activity of 23 antifungal drugs against 54 clinical and environmental Aspergillus oryzae isolates.
    Mycoses, 2022, Volume: 65, Issue:11

    Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Aspergillus oryzae; Clotrimazole; Econazole; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Terbinafine; Tolnaftate; Voriconazole

2022