Compounds > clotrimazole

clotrimazole and tram 34

clotrimazole has been researched along with tram 34 in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (58.33)29.6817
2010's10 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cahalan, MD; Chandy, KG; Grissmer, S; Hansel, W; Miller, MJ; Wulff, H1
Dreker, T; Feurle, J; Grissmer, S; Hamm, S; Kraus, J; Kuras, Z; Lang, M; Meere, C; Pegoraro, S; Prütting, S; Tasler, S; Visan, V1
Cahalan, MD; Chandy, KG; Gutman, GA; Wulff, H1
Borner, K; Brakemeier, S; Chandy, KG; Eichler, I; Grgic, I; Hoyer, J; Kämpfe, D; Kneifel, M; Knorr, A; Köhler, R; Neumann, D; Orzechowski, HD; Paul, M; Real, R; Reusch, HP; Si, H; Wibawa, J; Wulff, H1
Bauer, AL; Kobayashi, M; Manaves, V; Qin, W; Rane, SG; Rossie, S1
Berger, P; Bolton, SJ; Bradding, P; Cruse, G; Mark Duffy, S; Yang, W1
Brakemeier, S; Eichler, I; Grgic, I; Heinau, P; Hoyer, J; Köhler, R; Si, H1
Baell, J; Fowler, CJ; Furness, JB; Hunne, B; Matsuyama, H; Nguyen, TV; Nurgali, K; Smith, JE1
Feng, YJ; Jia, YC; Ren, J; Shen, B; Wang, YZ; Wang, ZH; Yao, HL1
Adragna, NC; Chimote, AA; Lauf, PK; Misri, S1
Hasegawa, Y; Lee, EL; Okada, Y; Shimizu, T1
Azam, P; Chandy, KG; Das, S; Fujiwara, Y; Gutterman, DD; Harder, DR; Hatoum, OA; Mattson, DL; Melvin, JE; Miura, H; Pratt, PF; Raman, G; Saito, T; Toyama, K; Wulff, H1
Chantome, A; Collin, C; Girault, A; Joulin, V; Pagès, JC; Potier, M; Vandier, C; Vaudin, P1
Ahidouch, A; Chopin, V; Faouzi, M; Ouadid-Ahidouch, H1
Dutta, AK; Esser, V; Feranchak, AP; Khimji, AK; Kresge, C; Parameswara, V; Rockey, DC; Sathe, M1
Hunter, M; Linley, JE; Lodge, JP; Loganathan, A; Rajput, I; Sandle, GI1
Bornstein, JC; Chambers, JD; Thomas, EA1
Maniak, PJ; O'Grady, SM; Palmer, ML; Peitzman, ER; Prakash, YS; Sieck, GC1
Colledge, WH; Mason, MJ; Shivakumar, O; Stoneking, CJ; Thomas, DN1
Sontheimer, H; Turner, KL1
Asslaber, D; Egle, A; Greil, R; Grössinger, EM; Hainzl, S; Hartmann, TN; Hinterseer, E; Kerschbaum, HH; Krenn, PW; Neureiter, D; Piñón-Hofbauer, J; Rebhandl, S; Schmölzer, J; Weiss, L; Zierler, S1
Huang, MH; Huang, YM; Wu, SN1
Liu, J; Shen, W; Yang, X; Yi, J; Yin, Q; Zhang, P; Zhao, L; Zhu, Z1
Bonito, B; Djamgoz, MB; Novak, I; Sauter, DR; Schwab, A1

Other Studies

24 other study(ies) available for clotrimazole and tram 34

ArticleYear
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, 07-05, Volume: 97, Issue:14

    Topics: Calcium Channel Blockers; Calcium Channels; Clotrimazole; Cyclosporine; Cytochrome P-450 Enzyme System; Drug Design; Drug Interactions; Electric Conductivity; Humans; Immunosuppressive Agents; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Channel Gating; Ionomycin; Lymphocyte Activation; Potassium Channels; Pyrazoles; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate

2000
Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants.
    Bioorganic & medicinal chemistry letters, 2009, Apr-15, Volume: 19, Issue:8

    Topics: Animals; Calcium Signaling; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Intermediate-Conductance Calcium-Activated Potassium Channels; Keratinocytes; Kv1.3 Potassium Channel; Patch-Clamp Techniques; Potassium Channel Blockers

2009
Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1.
    The Journal of biological chemistry, 2001, Aug-24, Volume: 276, Issue:34

    Topics: Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Clotrimazole; Cytoplasm; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Models, Molecular; Molecular Sequence Data; Potassium Channels; Protein Conformation; Pyrazoles; Sequence Homology, Amino Acid

2001
Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis.
    Circulation, 2003, Sep-02, Volume: 108, Issue:9

    Topics: Angioplasty, Balloon; Animals; Cell Line; Cells, Cultured; Clotrimazole; Epidermal Growth Factor; Graft Occlusion, Vascular; Hyperplasia; Intermediate-Conductance Calcium-Activated Potassium Channels; Large-Conductance Calcium-Activated Potassium Channels; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tunica Intima

2003
Calcium and Vitamin D increase mRNA levels for the growth control hIK1 channel in human epidermal keratinocytes but functional channels are not observed.
    BMC dermatology, 2004, Jun-16, Volume: 4

    Topics: Adult; Base Sequence; Benzimidazoles; Biopsy; Calcimycin; Calcitriol; Calcium; Cell Differentiation; Cells, Cultured; Charybdotoxin; Clotrimazole; DNA-Binding Proteins; Epidermal Cells; Humans; Ikaros Transcription Factor; Keratinocytes; Patch-Clamp Techniques; Pyrazoles; RNA, Messenger; Transcription Factors; Vitamin D

2004
The K+ channel iKCA1 potentiates Ca2+ influx and degranulation in human lung mast cells.
    The Journal of allergy and clinical immunology, 2004, Volume: 114, Issue:1

    Topics: Benzimidazoles; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Degranulation; Cells, Cultured; Clotrimazole; Histamine; Humans; Immunoglobulin E; Intermediate-Conductance Calcium-Activated Potassium Channels; Lung; Mast Cells; Patch-Clamp Techniques; Potassium Channels; Pyrazoles

2004
Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:4

    Topics: Cell Division; Cells, Cultured; Clotrimazole; Endothelium, Vascular; Gene Expression; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Microcirculation; Neovascularization, Physiologic; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Pyrazoles; RNA, Messenger; Umbilical Veins

2005
Effects of compounds that influence IK (KCNN4) channels on afterhyperpolarizing potentials, and determination of IK channel sequence, in guinea pig enteric neurons.
    Journal of neurophysiology, 2007, Volume: 97, Issue:3

    Topics: Animals; Benzimidazoles; Clotrimazole; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gene Expression; Guinea Pigs; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Channel Gating; Male; Membrane Potentials; Myenteric Plexus; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, Protein

2007
Blockage of intermediate-conductance-Ca(2+) -activated K(+) channels inhibits progression of human endometrial cancer.
    Oncogene, 2007, Aug-02, Volume: 26, Issue:35

    Topics: Animals; Cell Cycle; Cell Proliferation; Charybdotoxin; Clotrimazole; Endometrial Neoplasms; Female; G1 Phase; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Mice; Mice, Nude; Pyrazoles; Resting Phase, Cell Cycle; RNA, Small Interfering

2007
Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cells.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:3

    Topics: Acetates; Blotting, Western; Bumetanide; Cell Line; Cell Membrane Permeability; Cell Size; Chloride Channels; Clotrimazole; Cyclopentanes; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Immunohistochemistry; Indans; Indenes; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Channel Gating; K Cl- Cotransporters; Kinetics; Lens, Crystalline; Niflumic Acid; Nitrobenzoates; Osmosis; Ouabain; Phloretin; Potassium; Potassium Channel Blockers; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Rubidium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Spectrophotometry, Atomic; Symporters; Voltage-Dependent Anion Channels

2008
IK1 channel activity contributes to cisplatin sensitivity of human epidermoid cancer cells.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Calcium; Carcinoma, Squamous Cell; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Size; Cell Survival; Cisplatin; Clotrimazole; Drug Resistance, Neoplasm; Humans; Hypotonic Solutions; Immunochemistry; Intermediate-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction

2008
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:9

    Topics: Animals; Aorta; Atherosclerosis; Clotrimazole; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Macrophages; Mice; Mice, Transgenic; Models, Biological; Oxidative Stress; Pyrazoles; T-Lymphocytes

2008
KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility.
    Experimental cell research, 2009, Dec-10, Volume: 315, Issue:20

    Topics: Apamin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Clotrimazole; Electrophysiological Phenomena; Gene Expression; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Melanocytes; Melanoma; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrazoles; RNA, Antisense; Small-Conductance Calcium-Activated Potassium Channels; Transfection

2009
Intermediate Ca2+-sensitive K+ channels are necessary for prolactin-induced proliferation in breast cancer cells.
    The Journal of membrane biology, 2010, Volume: 234, Issue:1

    Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Clotrimazole; Female; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Janus Kinase 2; Prolactin; Pyrazoles; Receptors, Prolactin; Tyrphostins

2010
Identification and functional characterization of the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) in biliary epithelium.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:5

    Topics: Adenosine Triphosphate; Animals; Apamin; Barium; Benzimidazoles; Biliary Tract; Buffers; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Chelating Agents; Clotrimazole; Egtazic Acid; Electrophysiological Phenomena; Epithelial Cells; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intermediate-Conductance Calcium-Activated Potassium Channels; Models, Biological; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyrazoles; Rats; Signal Transduction; Suramin

2009
Basolateral potassium (IKCa) channel inhibition prevents increased colonic permeability induced by chemical hypoxia.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:1

    Topics: Clotrimazole; Colon; Deoxyglucose; Dinitrophenols; Glycolysis; Humans; Hypoxia; Intermediate-Conductance Calcium-Activated Potassium Channels; Intestinal Mucosa; Liver; Oxidative Phosphorylation; Patch-Clamp Techniques; Permeability; Pyrazoles

2011
Multiple neural oscillators and muscle feedback are required for the intestinal fed state motor program.
    PloS one, 2011, May-05, Volume: 6, Issue:5

    Topics: Action Potentials; Animals; Clotrimazole; Excitatory Postsynaptic Potentials; Feedback, Physiological; Feeding Behavior; Guinea Pigs; In Vitro Techniques; Jejunum; Models, Neurological; Motor Activity; Motor Neurons; Muscle Contraction; Muscles; Nerve Net; Neural Inhibition; Piperazines; Pyrazoles; Sensory Receptor Cells

2011
K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation.
    The Journal of physiology, 2011, Jul-15, Volume: 589, Issue:Pt 14

    Topics: Absorption; Adenosine Triphosphate; Apamin; Calcium; Cells, Cultured; Charybdotoxin; Clotrimazole; Egtazic Acid; Epithelial Cells; Humans; Ion Transport; Mammary Glands, Human; Membrane Potentials; Peptides; Potassium; Potassium Channels, Calcium-Activated; Purinergic Agonists; Pyrazoles; Receptors, Purinergic P2Y; Signal Transduction; Sodium; Uridine Triphosphate

2011
Voltage dependence of the Ca(2+)-activated K(+) channel K(Ca)3.1 in human erythroleukemia cells.
    American journal of physiology. Cell physiology, 2013, May-01, Volume: 304, Issue:9

    Topics: Calcium; Cell Line, Tumor; Charybdotoxin; Clotrimazole; Electric Stimulation; Gene Expression; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Leukemia, Erythroblastic, Acute; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Pyrazoles

2013
KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo.
    Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:9

    Topics: Animals; Brain; Calcium; Cell Movement; Central Nervous System Agents; Clotrimazole; Female; Immunohistochemistry; Intermediate-Conductance Calcium-Activated Potassium Channels; Intracellular Space; Male; Mice, Transgenic; Microscopy, Confocal; Neural Stem Cells; Olfactory Bulb; Patch-Clamp Techniques; Potassium; Pyrazoles; Tissue Culture Techniques; TRPC Cation Channels

2014
Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Antigens, CD19; Cell Proliferation; Clotrimazole; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Ki-67 Antigen; Leukemia, Lymphocytic, Chronic, B-Cell; Potassium Channel Blockers; Pyrazoles

2014
The Inhibition by Oxaliplatin, a Platinum-Based Anti-Neoplastic Agent, of the Activity of Intermediate-Conductance Ca²⁺-Activated K⁺ Channels in Human Glioma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 37, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Clotrimazole; Glioma; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Organoplatinum Compounds; Oxaliplatin; Patch-Clamp Techniques; Platinum; Pyrazoles; RNA, Messenger

2015
Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Clotrimazole; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; MCF-7 Cells; Pyrazoles; Triple Negative Breast Neoplasms; Up-Regulation

2016
K
    Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:11-12

    Topics: Action Potentials; Adenocarcinoma; Benzimidazoles; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Clotrimazole; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Pancreatic Neoplasms; Potassium Channel Blockers; Pyrazoles

2016