clotrimazole has been researched along with rifampin in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.16) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 17 (44.74) | 29.6817 |
| 2010's | 13 (34.21) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, WT; Schuetz, EG; Schuetz, JD | 1 |
| Burk, O; Eichelbaum, M; Geick, A | 1 |
| Benz, A; Kauffmann, HM; Pfannschmidt, S; Schrenk, D; Vorderstemann, B; Webster, JI; Zöller, H | 1 |
| Jekerle, V; Piquette-Miller, M; Teng, S | 1 |
| Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
| Brouillette, CG; Brouillette, WJ; DeLucas, LJ; Luan, CH; Mou, L; Velu, SE; Yang, ZW | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chitra, S; Manisankar, P; Muthusubramanian, S; Paul, N; Sriram, D; Yogeeswari, P | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Abell, C; Blankley, RT; Campbell, B; Charoensutthivarakul, S; Coyne, AG; de Carvalho, LPS; Evangelopoulos, D; Frederickson, M; Katariya, MM; Kavanagh, ME; Levy, CW; Leys, D; McLean, KJ; Munro, AW; Selvam, IR; Tunnicliffe, RB | 1 |
| Freerksen, E; Freerksen, R; Krüger-Thiemer, M; Rosenfeld, M | 1 |
| Piersantelli, N; Robert, L | 1 |
| Braito, A; Campelli, A; Corradi, GN | 1 |
| Brucker, G; Danis, M; Felix, H; Gentilini, M; Lebas, J; Mogahed, A | 1 |
| Hirata, M; Nishibe, Y | 1 |
| Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J | 1 |
| Furukawa, M; Nagata, K; Ogino, M; Okubo, T; Shimada, M; Yamazaki, T; Yamazoe, Y | 1 |
| Faucette, SR; Gilbert, D; Jolley, SL; LeCluyse, EL; Negishi, M; Sueyoshi, T; Wang, H | 1 |
| Akasawa, A; Hasegawa, R; Kamakura, S; Kitakaze, M; Komamura, K; Koyano, S; Kurose, K; Matsumoto, K; Nakajima, T; Ozawa, S; Saito, H; Saito, Y; Sawada, J; Ueno, K | 1 |
| Chirulli, V; Fiorio, R; Gervasi, PG; Longo, V; Marini, S; Mazzaccaro, A | 1 |
| Ahmad, Z; Khuller, GK; Sharma, S | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
| Huang, JD; Lim, YP | 1 |
| Gui, C; Hagenbuch, B; Miao, Y; Mock, M; Stieger, B; Thompson, L; Wahlgren, B | 1 |
| Aikawa, K; Matsunaga, T; Nakamura, K; Ohmori, S; Takezawa, T | 1 |
2 review(s) available for clotrimazole and rifampin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Special therapeutic aspects of cryptococcal meningoencephalitis].
Topics: Amphotericin B; Antifungal Agents; Child; Clotrimazole; Cryptococcosis; Cryptococcus neoformans; Drug Therapy, Combination; Estrogens; Female; Flucytosine; Humans; Immunologic Techniques; Male; Meningoencephalitis; Miconazole; Middle Aged; Phagocytosis; Rifampin; Transfer Factor | 1976 |
36 other study(ies) available for clotrimazole and rifampin
| Article | Year |
|---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil | 1996 |
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors | 2001 |
Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression.
Topics: Arsenites; Cell Line; Clotrimazole; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Humans; Hydroquinones; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Oxidation-Reduction; Pregnane X Receptor; Quercetin; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Ribosomal Proteins; Rifampin; RNA, Messenger; Saccharomyces cerevisiae Proteins | 2002 |
Induction of ABCC3 (MRP3) by pregnane X receptor activators.
Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger | 2003 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups.
Topics: Amide Synthases; Amides; Amino Acids; Anti-Bacterial Agents; Bacillus subtilis; Detergents; Dimerization; Ethers; Gram-Positive Bacteria; Microbial Sensitivity Tests; NAD; Octoxynol; Structure-Activity Relationship | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies.
Topics: Anti-Bacterial Agents; Azoles; Candida albicans; Chemistry Techniques, Synthetic; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen).
Topics: Antitubercular Agents; Drug Design; Humans; Mycobacterium tuberculosis; Tuberculosis; X-Rays | 2022 |
[New methods for clearing salmonella excretors (author's transl)].
Topics: Carrier State; Clotrimazole; Feces; Humans; Rifampin; Salmonella Infections | 1977 |
Drugs for the treatment of systemic fungal infections.
Topics: Amphotericin B; Clotrimazole; Drug Therapy, Combination; Flucytosine; Humans; Kidney Diseases; Meningitis; Miconazole; Mycoses; Rifampin; Thrombophlebitis | 1978 |
[A case of generalized Candida albicans infection].
Topics: Adolescent; Antifungal Agents; Candidiasis; Candidiasis, Oral; Candidiasis, Vulvovaginal; Cefazolin; Clotrimazole; Female; Gastrointestinal Diseases; Humans; Lung Diseases, Fungal; Prednisolone; Rifampin | 1975 |
[Histoplasmosis: clinical, biological, and therapeutic aspects in ten cases (author's transl)].
Topics: Adolescent; Adult; Africa; Aged; Amphotericin B; Child; Child, Preschool; Clotrimazole; Female; Histoplasmosis; Humans; Infant; Lymph Node Excision; Male; Miconazole; Middle Aged; Mouth Diseases; Rifampin | 1980 |
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases | 1995 |
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors | 2001 |
Adenovirus vector-mediated reporter system for in vivo analyses of human CYP3A4 gene activation.
Topics: Adenoviridae; Animals; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Glucocorticoids; Growth Inhibitors; Humans; Liver; Luciferases; Male; Mice; Mixed Function Oxygenases; Promoter Regions, Genetic; Rifampin; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Topics: Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Clotrimazole; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Gene Expression Regulation; Hepatocytes; Humans; Hydroxylation; Immunoblotting; Ligands; Oxidoreductases, N-Demethylating; Phenytoin; Polymerase Chain Reaction; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Receptors, Steroid; Rifampin; RNA, Messenger; Transcription Factors | 2003 |
Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Topics: Amino Acid Sequence; Animals; Biotransformation; Blotting, Western; Cell Line, Tumor; Chlorocebus aethiops; Clotrimazole; COS Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA; Electrophoretic Mobility Shift Assay; Enhancer Elements, Genetic; Exons; Genes, Reporter; Humans; Immunohistochemistry; Luciferases; Molecular Sequence Data; Paclitaxel; Plasmids; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Transcriptional Activation | 2004 |
CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.
Topics: Air Pollutants; Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Calcium-Binding Proteins; Clotrimazole; Cytochrome P-450 CYP3A; Dexamethasone; Enzyme Induction; Eye Proteins; Isoenzymes; Lipoproteins; Lung; Male; Organ Specificity; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Pregnane X Receptor; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recoverin; Rifampin; Species Specificity | 2005 |
In vitro and ex vivo antimycobacterial potential of azole drugs against Mycobacterium tuberculosis H37Rv.
Topics: Anti-Bacterial Agents; Clotrimazole; Colony Count, Microbial; Drug Synergism; Econazole; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin | 2005 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |
Pregnane X receptor polymorphism affects CYP3A4 induction via a ligand-dependent interaction with steroid receptor coactivator-1.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, Affinity; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Growth Inhibitors; Histone Acetyltransferases; Humans; Immunoprecipitation; Ligands; Mutagenesis, Site-Directed; Mutation; Nuclear Receptor Coactivator 1; Paclitaxel; Plasmids; Polymorphism, Genetic; Pregnane X Receptor; Receptors, Steroid; Rifampin; Transcription Factors; Transcriptional Activation; Two-Hybrid System Techniques | 2007 |
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
Topics: Animals; CHO Cells; Chromans; Clotrimazole; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrone; Humans; Kinetics; Ligands; Liver-Specific Organic Anion Transporter 1; Mifepristone; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Pregnane X Receptor; Receptors, Steroid; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Thiazolidinediones; Transfection; Troglitazone; Xenobiotics | 2008 |
Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
Topics: Clotrimazole; CREB-Binding Protein; Cytochrome P-450 CYP3A; Dexamethasone; Down-Regulation; Enzyme Induction; Genes, Reporter; Heat-Shock Proteins; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Humans; Liver; Mifepristone; Nuclear Receptor Coactivator 1; p300-CBP Transcription Factors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnane X Receptor; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Transcription Factors; Transfection; Up-Regulation | 2012 |