clotrimazole has been researched along with metyrapone in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jekerle, V; Piquette-Miller, M; Teng, S | 1 |
| Pratim Roy, P; Roy, K | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Campbell, WB; Falck, JR; Pfister, SL | 1 |
| Napoli, JL; Williams, JB | 1 |
| DePierre, JW; Guenthner, TM; Oesch, F; Seidegård, J | 1 |
| Bernhardt, R; Denner, K; Doehmer, J; Schmalix, W; Vogel, R | 1 |
| Hänninen, O; Kaliste-Korhonen, E; Kärenlampi, S; Laaksonen, M | 1 |
| Alvinerie, M; Dupuy, J; Eeckhoutte, C; Escudero, E; Galtier, P; Sutra, JF | 1 |
| Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J | 1 |
| Linster, CL; Van Schaftingen, E | 1 |
1 review(s) available for clotrimazole and metyrapone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
13 other study(ies) available for clotrimazole and metyrapone
| Article | Year |
|---|---|
Induction of ABCC3 (MRP3) by pregnane X receptor activators.
Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger | 2003 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acids; Carbon Radioisotopes; Cholesterol, Dietary; Clotrimazole; Diet, Atherogenic; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Kinetics; Masoprocol; Metyrapone; Muscle, Smooth, Vascular; Rabbits; Reference Values; Stereoisomerism | 1991 |
Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells.
Topics: Cell Line; Clotrimazole; Embryonal Carcinoma Stem Cells; Imidazoles; Ketoconazole; Metyrapone; Miconazole; Neoplastic Stem Cells; Tretinoin | 1987 |
The effects of metyrapone, chalcone epoxide, benzil, clotrimazole and related compounds on the activity of microsomal epoxide hydrolase in situ, in purified form and in reconstituted systems towards different substrates.
Topics: Aldehydes; Animals; Chalcone; Chalcones; Clotrimazole; Dose-Response Relationship, Drug; Enzyme Activation; Epoxide Hydrolases; Humans; Hydrogen-Ion Concentration; Imidazoles; Liposomes; Male; Metyrapone; Mice; Microsomes; Phenylglyoxal; Propiophenones; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Cloning and stable expression of the human mitochondrial cytochrome P45011B1 cDNA in V79 Chinese hamster cells and their application for testing of potential inhibitors.
Topics: Adrenal Glands; Animals; Base Sequence; Cell Line; Cloning, Molecular; Clotrimazole; Cricetinae; Cricetulus; DNA Primers; DNA, Complementary; Fluconazole; Gene Expression; Hydrocortisone; Hydroxylation; Ketoconazole; Kinetics; Metyrapone; Miconazole; Mitochondria; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Spironolactone; Steroid 11-beta-Hydroxylase; Transfection | 1995 |
P450 enzyme CYP2B catalyzes the detoxification of diisopropyl fluorophosphate.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Clotrimazole; Cricetinae; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Isoflurophate; Isoquinolines; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases | 1995 |
In vitro metabolism of 14C-moxidectin by hepatic microsomes from various species.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antinematodal Agents; Benzoflavones; Carbon Radioisotopes; Cattle; Clotrimazole; Deer; Enzyme Inhibitors; Female; Macrolides; Male; Metyrapone; Microsomes, Liver; Pesticide Synergists; Piperonyl Butoxide; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Sheep; Swine | 2001 |
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors | 2001 |
Rapid stimulation of free glucuronate formation by non-glucuronidable xenobiotics in isolated rat hepatocytes.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Ascorbic Acid; Barbital; Buthionine Sulfoximine; Cells, Cultured; Chlorobutanol; Chromatography, High Pressure Liquid; Clotrimazole; Diamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactosamine; Glucuronates; Glucuronic Acid; Hepatocytes; Imidazoles; Imidazolidines; Metyrapone; Models, Chemical; Preservatives, Pharmaceutical; Proadifen; Rats; Rats, Wistar; Resorcinols; Time Factors; Xenobiotics; Xylulose | 2003 |