Compounds > clotrimazole

clotrimazole and lanosterol

clotrimazole has been researched along with lanosterol in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL1
Kelly, DE; Kelly, SL; Martel, CM; Melo, N; Nes, WD; Parker, JE; Warrilow, AG1
Feingold, DS; Sud, IJ2
Barbuch, R; Bard, M; Gachotte, D; Koegel, C; Lees, ND; Pierson, CA1
Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG1

Other Studies

7 other study(ies) available for clotrimazole and lanosterol

ArticleYear
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3

    Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase

2007
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Amino Acid Sequence; Aspergillus fumigatus; Azoles; Clotrimazole; Drug Resistance, Multiple, Fungal; Fluconazole; Fungal Proteins; Isoenzymes; Itraconazole; Lanosterol; Molecular Sequence Data; Protein Binding; Pyrimidines; Sequence Homology, Amino Acid; Sterol 14-Demethylase; Substrate Specificity; Triazoles; Voriconazole

2010
Heterogeneity of action of mechanisms among antimycotic imidazoles.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Antifungal Agents; Clotrimazole; Ergosterol; Imidazoles; Ketoconazole; Lanosterol; Miconazole; Piperazines; Saccharomyces cerevisiae

1981
Mechanisms of action of the antimycotic imidazoles.
    The Journal of investigative dermatology, 1981, Volume: 76, Issue:6

    Topics: Clotrimazole; Dose-Response Relationship, Drug; Ergosterol; Imidazoles; Lanosterol; Miconazole; Microbial Sensitivity Tests; Saccharomyces cerevisiae

1981
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Antifungal Agents; Azoles; Clotrimazole; Genes, Fungal; Genotype; Heme; Itraconazole; Ketoconazole; Lanosterol; Mixed Function Oxygenases; Mutation; Saccharomyces cerevisiae; Sterols; Suppression, Genetic

1997
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole

2013
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole

2016