clotrimazole and indomethacin

clotrimazole has been researched along with indomethacin in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.82)18.7374
1990's11 (25.00)18.2507
2000's14 (31.82)29.6817
2010's16 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Al-Deeb, OA; El-Brollosy, NR; El-Emam, AA; Habib, EE; Ibrahim, TM; Kadi, AA1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Al-Abdullah, ES; El-Emam, AA; Habib, EE; Ibrahim, TM; Kadi, AA; Shehata, IA1
Ekins, S; Williams, AJ; Xu, JJ1
Bekhit, AA; El-Din A Bekhit, A; Fahmy, HT; Rostom, SA1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Nagi Reddy, M; Rajam, MV; Rajanarendar, E; Rama Krishna, S; Rama Murthy, K; Reddy, YN1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dieppe, PA; Huskisson, EC; Kirby, JD; Stevens, C; Willoughby, DA1
Cassola, A; Giebisch, G; Wang, W1
Campbell, WB; Falck, JR; Pfister, SL1
McGiff, JC; Oyekan, AO; Quilley, J1
Capdevila, J; Falck, JR; Gil, L; Marnett, LJ; Mason, JI; Orellana, M; Yadagiri, P1
Austen, KF; Corey, EJ; Drazen, JM; Leitch, AG1
Oyekan, AO1
Ekokoski, E; Forss, L; Törnquist, K1
Aussel, C; Bernard, A; Berthe, P; Breittmayer, JP; Cousin, JL1
Davis, SC; Edwards, G; Högestätt, ED; Weston, AH; Zygmunt, PM1
Gimeno, MA; Gonzalez, E; Jawerbaum, A; Novaro, V1
Ishizaka, H; Kuo, L1
McGiff, JC; Oyekan, AO1
Archuleta, I; Kluger, MJ; Kozak, A; Kozak, W; Mayfield, KP; Rudolph, K1
Assmann, G; Junker, R; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Zidek, W1
Linsdell, P1
Bautista, R; Escalante, B; Hernández, J; Oyekan, A; Sánchez, A1
Assreuy, J; Pompermayer, K; Vieira, MA1
Baker, PN; Dunn, WR; Kendall, DA; Kenny, LC; Randall, MD1
Kompanowska-Jezierska, E; Sadowski, J; Walkowska, A1
Canals, S; Casarejos, MJ; de Bernardo, S; Mena, MA; Rodríguez-Martín, E1
Qiu, Y; Quilley, J1
Boban, M; Brizic, I; Budimir, D; Katalinic, V; Modun, D; Vukovic, J1
Leung, SW; Vanhoutte, PM; Zhao, Y1
Delgado, NT; Menezes, JB; Moyses, MR; Rouver, WN; Santos, RL1

Reviews

1 review(s) available for clotrimazole and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

43 other study(ies) available for clotrimazole and indomethacin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:2

    Topics: Adamantane; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Colony Count, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Microbial Sensitivity Tests; Oxadiazoles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiadiazoles

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Candida albicans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Thiadiazoles

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Candida albicans; Carrageenan; Catalytic Domain; Cotton Fiber; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Escherichia coli; Granuloma; Humans; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Thiazoles

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Design, synthesis, antimicrobial, anti-inflammatory and analgesic activity of novel isoxazolyl pyrimido[4,5-b]quinolines and isoxazolyl chromeno[2,3-d]pyrimidin-4-ones.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Behavior, Animal; Chemistry Techniques, Synthetic; Drug Design; Edema; Fungi; Isoxazoles; Microbial Sensitivity Tests; Pyrimidinones; Quinolines; Rats

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Symposium on specific therapy for rheumatoid arthritis: specific therapy in new conventional animal models.
    Rheumatology and rehabilitation, 1976, Volume: 15, Issue:3

    Topics: Animals; Arthritis, Rheumatoid; Clotrimazole; Dexamethasone; Disease Models, Animal; Gold; Indomethacin; Levamisole; Male; Mice; Penicillamine; Rats

1976
Arachidonic acid inhibits the secretory K+ channel of cortical collecting duct of rat kidney.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 2

    Topics: Animals; Arachidonic Acid; Clotrimazole; Female; Indomethacin; Kidney Cortex; Kidney Tubules, Collecting; Male; Masoprocol; Oleic Acid; Oleic Acids; Potassium Channels; Rats; Rats, Inbred Strains; Stereoisomerism

1992
Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acids; Carbon Radioisotopes; Cholesterol, Dietary; Clotrimazole; Diet, Atherogenic; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Kinetics; Masoprocol; Metyrapone; Muscle, Smooth, Vascular; Rabbits; Reference Values; Stereoisomerism

1991
Cytochrome P-450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat.
    Circulation research, 1991, Volume: 68, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Clotrimazole; Cytochrome P-450 Enzyme System; In Vitro Techniques; Indomethacin; Kidney; Male; Oxazines; Phenylephrine; Rats; Rats, Inbred Strains; Renal Circulation; Sulfonamides; Vasoconstriction; Vasodilation; Vasodilator Agents

1991
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
    Archives of biochemistry and biophysics, 1988, Volume: 261, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains

1988
The effect of indomethacin on the contractile response of the guinea-pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4.
    British journal of pharmacology, 1983, Volume: 80, Issue:1

    Topics: Animals; Clotrimazole; Drug Interactions; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; SRS-A

1983
Role of the cytochrome P450 enzyme system as a humoral modulator of vasomotor responses in rat renal vasculature.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:2

    Topics: Animals; Arachidonic Acid; Benzoflavones; Calcium; Clotrimazole; Cytochrome P-450 Enzyme System; Indomethacin; Kidney; Male; Perfusion; Rats; Vasoconstriction

1994
Thapsigargin-induced calcium entry in FRTL-5 cells: possible dependence on phospholipase A2 activation.
    Journal of cellular physiology, 1994, Volume: 160, Issue:1

    Topics: Acetophenones; Animals; Arachidonic Acid; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Enzyme Activation; Indomethacin; Leukotrienes; Masoprocol; Phospholipases A; Phospholipases A2; Rats; Terpenes; Thapsigargin; Thyroid Gland

1994
CD3 monoclonal antibodies evoke the same cytochrome P450-regulated capacitative entry of calcium as thapsigargin in Jurkat T cells.
    Cellular immunology, 1993, Volume: 152, Issue:1

    Topics: Calcium; Cell Line; Cell Membrane Permeability; Clotrimazole; Econazole; Humans; Indoles; Indomethacin; Masoprocol; Membrane Potentials; Muromonab-CD3; T-Lymphocytes; Terpenes; Thapsigargin

1993
Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Acetylcholine; Animals; Benzopyrans; Biological Factors; Clotrimazole; Cromakalim; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hepatic Artery; Indomethacin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Potassium Channels; Proadifen; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents

1996
Influence of epoxyeicosatrienoic acids on uterine function.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Estradiol; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Ovariectomy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Uterine Contraction

1997
Endothelial ATP-sensitive potassium channels mediate coronary microvascular dilation to hyperosmolarity.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Animals; Apamin; Arterioles; Clotrimazole; Coronary Circulation; Cytochrome P-450 Enzyme Inhibitors; Endothelium, Vascular; Glucose; Glyburide; Hypertonic Solutions; In Vitro Techniques; Indomethacin; Kinetics; Microcirculation; NG-Nitroarginine Methyl Ester; Nitroprusside; Peptides; Potassium Channels; Potassium Chloride; Sucrose; Swine; Vasodilation

1997
Cytochrome P-450-derived eicosanoids participate in the renal functional effects of ET-1 in the anesthetized rat.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Anesthesia, General; Animals; Clotrimazole; Cobalt; Cytochrome P-450 Enzyme System; Eicosanoids; Endothelin-1; Fatty Acids, Monounsaturated; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Vascular Resistance

1998
Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Antioxidants; Arachidonic Acid; Body Temperature; Body Temperature Regulation; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Fever; Indomethacin; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Proadifen; Pyrazoles; Time Factors; Umbelliferones

1998
Phospholipase A(2) is involved in thapsigargin-induced sodium influx in human lymphocytes.
    Archives of biochemistry and biophysics, 2000, Feb-15, Volume: 374, Issue:2

    Topics: Acetophenones; Acrylates; Arachidonic Acid; Benzoates; Cell Membrane; Clotrimazole; Econazole; Humans; In Vitro Techniques; Indomethacin; Kinetics; Lymphocytes; Masoprocol; Naphthalenes; Phosphodiesterase Inhibitors; Phospholipases A; Pyrones; Sodium; Thapsigargin

2000
Inhibition of cystic fibrosis transmembrane conductance regulator chloride channel currents by arachidonic acid.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:6

    Topics: Animals; Arachidonic Acid; Cell Line; Clotrimazole; Cricetinae; Cyclooxygenase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Fatty Acids; Growth Inhibitors; Indomethacin; Kidney; Masoprocol; Membrane Potentials

2000
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation

2001
Involvement of nitric oxide and potassium channels in the bradykinin-induced vasodilatation in the rat kidney perfused ex situ.
    Regulatory peptides, 2002, May-30, Volume: 105, Issue:3

    Topics: Animals; Bradykinin; Clotrimazole; Hemodynamics; In Vitro Techniques; Indomethacin; Ion Channels; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Vascular Resistance; Vasodilation

2002
The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women.
    British journal of pharmacology, 2002, Volume: 136, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Biological Factors; Bradykinin; Cannabinoids; Carbenoxolone; Clotrimazole; Cyclooxygenase Inhibitors; Endothelium, Vascular; Fatty Acids, Monounsaturated; Female; Gap Junctions; Glycyrrhetinic Acid; Humans; In Vitro Techniques; Indomethacin; Myometrium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Pregnancy; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vasoconstrictor Agents; Vasodilation

2002
Role of prostaglandin cyclooxygenase and cytochrome P450 pathways in the mechanism of natriuresis which follows hypertonic saline infusion in the rat.
    Acta physiologica Scandinavica, 2003, Volume: 177, Issue:1

    Topics: Animals; Clotrimazole; Cytochrome P-450 Enzyme System; Indomethacin; Infusions, Intra-Arterial; Kidney; Male; Natriuresis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Renal Circulation; Saline Solution, Hypertonic

2003
Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase.
    The Journal of biological chemistry, 2003, Jun-13, Volume: 278, Issue:24

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 12-Lipoxygenase; Blotting, Western; Brain; Cell Membrane; Cell Survival; Cells, Cultured; Clotrimazole; Culture Media; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Flavonoids; Free Radical Scavengers; Glutathione; Growth Inhibitors; Immunohistochemistry; Indomethacin; Inhibitory Concentration 50; Leukotrienes; Masoprocol; Mesencephalon; Microscopy, Fluorescence; Nitric Oxide; Platelet Aggregation Inhibitors; Protein Binding; Rats; Signal Transduction; Time Factors

2003
K(+)-induced vasodilation in the rat kidney is dependent on the endothelium and activation of K+ channels.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Barium Compounds; Bradykinin; Carbenoxolone; Chlorides; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium; Glyburide; Indomethacin; Kidney; Male; Muscle Contraction; Nitric Oxide; Nitroarginine; Nitroprusside; Phenylephrine; Potassium; Potassium Channels; Prostaglandins; Rats; Rats, Wistar; Tetraethylammonium

2005
Differences in vasodilatory response to red wine in rat and guinea pig aorta.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Clotrimazole; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Species Specificity; Vasodilation; Vasodilator Agents; Wine

2009
Endothelial nitric oxide synthase-independent release of nitric oxide in the aorta of the spontaneously hypertensive rat.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1

    Topics: Animals; Aorta, Thoracic; Clotrimazole; Cyclooxygenase Inhibitors; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Humans; In Vitro Techniques; Indomethacin; Male; NADPH-Ferrihemoprotein Reductase; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Onium Compounds; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Vasoconstrictor Agents

2013
Testosterone Replacement Therapy Prevents Alterations of Coronary Vascular Reactivity Caused by Hormone Deficiency Induced by Castration.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Animals; Blood Pressure; Bradykinin; Cardiovascular System; Castration; Clotrimazole; Coronary Vessels; Endothelium, Vascular; Heart; Hormone Replacement Therapy; Indomethacin; Lipids; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Testosterone; Vasodilation; Vasodilator Agents

2015