clotrimazole and heme

clotrimazole has been researched along with heme in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Barbuch, R; Bard, M; Gachotte, D; Koegel, C; Lees, ND; Pierson, CA1
Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Tajima, K; Takano, R; Yamamoto, T1
Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R1
Hara, S; Huy, NT; Kamei, K; Takano, R1
Bandyopadhyay, U; Chand, P; Maulik, PR; Puri, SK; Srivastava, K; Trivedi, V1
Basilico, N; Butini, S; Campiani, G; Coccone, SS; Coletta, M; Croft, S; Fattorusso, C; Fattorusso, E; Fiorini, I; Gemma, S; Joshi, BP; Kukreja, G; Marini, S; Morace, G; Nacci, V; Novellino, E; Parapini, S; Persico, M; Savini, L; Taglialatela-Scafati, O; Taramelli, D; Yardley, V1
Kang, NS; Kang, YK; Lee, JY1
Acharya, D; Goswami, D; Patel, SK; Poojara, L; Prajapati, J; Rao, P; Rawal, RM1
Hsu, MH; Johnson, EF1

Other Studies

9 other study(ies) available for clotrimazole and heme

ArticleYear
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Antifungal Agents; Azoles; Clotrimazole; Genes, Fungal; Genotype; Heme; Itraconazole; Ketoconazole; Lanosterol; Mixed Function Oxygenases; Mutation; Saccharomyces cerevisiae; Sterols; Suppression, Genetic

1997
Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole.
    The Journal of biological chemistry, 2002, Feb-08, Volume: 277, Issue:6

    Topics: Animals; Antimalarials; Clotrimazole; Glutathione; Heme; Hemolysis; Humans; Plasmodium falciparum; Protein Binding; Spectrum Analysis

2002
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
    Journal of biochemistry, 2002, Volume: 131, Issue:3

    Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Erythrocytes; Glutathione; Heme; Hemolysis; Humans; In Vitro Techniques; Ketoconazole; Miconazole; Peptides; Plasmodium falciparum; Spectrum Analysis

2002
Enhancement of heme-induced membrane damage by the anti-malarial clotrimazole: the role of colloid-osmotic forces.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: Animals; Antimalarials; Clotrimazole; Colloids; Erythrocyte Membrane; Heme; Hemolysis; Humans; In Vitro Techniques; Lipid Peroxidation; Osmosis; Oxidation-Reduction; Sucrose

2004
Clotrimazole inhibits hemoperoxidase of Plasmodium falciparum and induces oxidative stress. Proposed antimalarial mechanism of clotrimazole.
    The Journal of biological chemistry, 2005, Dec-16, Volume: 280, Issue:50

    Topics: Animals; Antigens, Protozoan; Antimalarials; Catalysis; Clotrimazole; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Free Radicals; Glutathione; Growth Inhibitors; Heme; Hemeproteins; Hydrogen Peroxide; Kinetics; Lipid Peroxidation; Mass Spectrometry; Models, Chemical; Nitrogen; Oxidative Stress; Oxygen; Peroxidases; Plasmodium falciparum; Protein Binding; Reactive Oxygen Species; Spectrometry, Fluorescence; Spectrophotometry; Time Factors

2005
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Animals; Antifungal Agents; Antimalarials; Cell Line; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Female; Ferric Compounds; Heme; Humans; In Vitro Techniques; Mice; Models, Molecular; Oxidoreductases; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium chabaudi; Plasmodium falciparum; Protoporphyrins; Stereoisomerism; Sterol 14-Demethylase; Structure-Activity Relationship

2008
Binding free energies of inhibitors to iron porphyrin complex as a model for Cytochrome P450.
    Biopolymers, 2012, Volume: 97, Issue:4

    Topics: Biophysics; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Econazole; Enzyme Inhibitors; Heme; Humans; Iron; Models, Molecular; Molecular Mimicry; Piroxicam; Porphyrins; Protein Binding; Protein Conformation; Quantum Theory; Thermodynamics; Water; Xenobiotics

2012
A Comprehensive in vitro and in silico Assessment on Inhibition of CYP51B and Ergosterol Biosynthesis by Eugenol in Rhizopus oryzae.
    Current microbiology, 2022, Dec-20, Volume: 80, Issue:1

    Topics: Antifungal Agents; Clotrimazole; Ergosterol; Eugenol; Heme; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mucormycosis; Rhizopus; Rhizopus oryzae

2022
Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochromes P450 3A5 and 3A4.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:12

    Topics: Clotrimazole; Cytochrome P-450 CYP3A; Heme; Humans; Iron; Phenylalanine; X-Rays

2023