clothianidin has been researched along with 1-2-dioctanoylglycerol* in 1 studies
1 other study(ies) available for clothianidin and 1-2-dioctanoylglycerol
| Article | Year |
|---|---|
Effects of the DAG analogue 1,2-dioctanoyl-sn-glycerol (DiC8) on nicotine- and clothianidin-evoked currents through α-bungarotoxin-insensitive nicotinic acetylcholine receptors expressed on cockroach neurosecretory cells.
We previously demonstrated that the cockroach α-bungarotoxin-sensitive nicotinic acetylcholine receptors, nAChR1 and nAChR2 subtypes, are differently sensitive to intracellular calcium pathways. Here, using whole cell patch-clamp recordings, we studied the effects of the diacylglycerol (DAG) analogue 1,2-dioctanoyl-sn-glycerol (DiC8) on nicotine- and clothianidin-evoked currents under an α-bungarotoxin treatment. Our results demonstrated that DiC8 reduced nicotine and clothianidin evoked currents. 10 μM DiC8 suppressed the increase in nicotine-induced currents which was brought about by application of 5 mM caffeine or 9 mM Ca Topics: Animals; Bungarotoxins; Calcium Signaling; Cockroaches; Diglycerides; Guanidines; Male; Membrane Potentials; Neonicotinoids; Neurons; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Thiazoles | 2020 |