clorazepate dipotassium has been researched along with diazepam in 93 studies
| Studies (clorazepate dipotassium) | Trials (clorazepate dipotassium) | Recent Studies (post-2010) (clorazepate dipotassium) | Studies (diazepam) | Trials (diazepam) | Recent Studies (post-2010) (diazepam) |
|---|---|---|---|---|---|
| 325 | 90 | 11 | 18,377 | 2,329 | 1,790 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (89.25) | 18.7374 |
| 1990's | 5 (5.38) | 18.2507 |
| 2000's | 4 (4.30) | 29.6817 |
| 2010's | 1 (1.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallant, DM; McFarlain, RA; Mielke, DH | 1 |
| Clarke, CH; Ferres, HM; Nicholson, AN; Stone, BM | 1 |
| Solomon, K | 1 |
| Borland, RG; Nicholson, AN | 1 |
| Aliverti, V; Mariani, L | 1 |
| Pilbrant, A; Sundwall, A; Vessman, J; Wretlind, M | 1 |
| Greenblatt, DJ; Shader, RI | 4 |
| Carrigan, PJ; Chun, AH; Hoffman, DJ; Kershner, RP; Stuart, JD | 1 |
| Bertler, A; Lindgren, S; Malmgren, H; Post, C | 1 |
| Curry, SH; Dean, BC; Magnus, RV | 1 |
| Burrows, GD; Dumovic, P; Maguire, K; Norman, T; Smith, JA | 1 |
| Greenblatt, DJ | 1 |
| Henry, P; van den Driessche, J | 1 |
| Allen, MD; Georgotas, A; Greenblatt, DJ; Harmatz, JS; Shader, RI | 1 |
| Cucuianu, M; Cuparencu, B; Hâncu, N; Horák, J; Negrea, S; Seuşan, E; Vincze, J | 1 |
| Challier, JC; d'Athis, P; Guerre-Millo, M; Olive, G; Rey, E; Turquais, JM | 1 |
| Chavinie, J; d'Athis, P; Giraux, P; Olive, G; Rey, E; Turquais, JM | 1 |
| Fabre, LF; Mallette, A; McLendon, DM | 1 |
| Allen, MD; Bodem, G; Greenblatt, DJ; Harmatz, JS; Ochs, HR; Shader, RI | 1 |
| Bailey, D; Dobular, K; Jatlow, P | 1 |
| Georgotas, A; Greenblatt, DJ; Harmatz, JS; Shader, RI | 1 |
| Franzke, HG; Skupin, G | 1 |
| Dureman, I; Norrman, B | 1 |
| Lapierre, YD | 1 |
| Chun, AH; Hoffman, DJ | 1 |
| Keeler, MH; Miller, WC | 1 |
| Wada, JA | 1 |
| Curry, SH; Nicholson, AN; Whelpton, R; Wright, CM | 1 |
| Miller, RR | 1 |
| Kaistha, KK; Tadrus, R | 1 |
| Greenblatt, DJ; Koch-Weser, J; Shader, RI | 1 |
| Danielson, MG; Fowler, GW; Julien, RM | 1 |
| Azcarate, CL; Koepke, HH; Lion, JR | 1 |
| Daubländer, M; Lipp, M | 1 |
| Bertler, A; Lindgren, S; Magnusson, JO; Malmgren, H | 1 |
| Griffith, JL | 1 |
| Ciancio, SG | 1 |
| Alderdice, MT; Marunycz, JD; Napoliello, MJ; Newton, RE | 1 |
| Geller, AM; Lucki, I; Rickels, K | 1 |
| Greenblatt, DJ; Locniskar, A; Ochs, HR; Weinbrenner, J | 1 |
| Boxenbaum, HG; Divoll, MK; Greenblatt, DJ; Harmatz, JS; Shader, RI; Soong, MH | 1 |
| Vining, EP | 1 |
| Case, WG; Downing, RW; Rickels, K; Winokur, A | 1 |
| Curry, SH; Robin, A; Whelpton, R | 1 |
| Davenport, R; Haidukewych, D; Rodin, EA | 1 |
| Baker, WJ; Curry, S; Lader, MH | 1 |
| Allegre, G; Borenstein, P; Brindeau, F; Gekiere, F | 1 |
| Burrows, GD; Fulton, A; Maguire, KP; Norman, TR | 1 |
| Ciraulo, DA; Divoll, M; Georgotas, A; Greenblatt, DJ; Harmatz, JS; Shader, RI | 1 |
| Franzke, HG; Henschel, WF; Skubella, U | 1 |
| Ciraulo, DA; Greenblatt, DJ; Harmatz, JS; Shader, RI | 1 |
| Kanto, JH | 1 |
| Greenblatt, DJ; Knüchel, M; Locniskar, A; Ochs, HR; Steinhaus, E | 1 |
| Nicholson, AN | 1 |
| Berthe, J; Gouy, D; Mazue, G; Remandet, B; Roncucci, R; Williams, GM | 1 |
| Wheatley, D | 1 |
| Henderson, JG | 1 |
| Alms, DR; Benes, CO; Casten, GP; Marunycz, JD; Newton, RE | 1 |
| Gershon, S | 1 |
| Allen, RM | 1 |
| Colin, P; Lelorier, J; Sirois, G | 1 |
| Carrasco Prieto, A; Castillo-Ferrando, JR; De La Torre Brasas, F | 1 |
| Käferstein, H; Norpoth, T; Staak, M; Sticht, G | 1 |
| Healey, M; McKenna, T; Meisch, R; Pickens, R | 1 |
| Belghiti, J; Boivin, P; Gautero, H; Goldfarb, G | 1 |
| Harris, PG | 1 |
| Olive, G; Rey, E | 1 |
| Greenblatt, DJ; Kaschell, HJ; Ochs, HR; Rauh, HW | 1 |
| Brown, J; Burrows, G; Callan, A; Dennerstein, L; Fulton, A; Montalto, J; Notelovitz, M; Warne, G | 1 |
| Allison, S; Greenblatt, DJ; Harmatz, JS; Locniskar, A; Pary, RJ; Shader, RI | 1 |
| Greenblatt, DJ; Locniskar, A; Ochs, HR; Verburg-Ochs, B | 1 |
| Itoh, N; Mimaki, T; Ono, J; Tagawa, T; Tanaka, J; Terada, H; Yabuuchi, H | 1 |
| Diehl, LW; Werner, V | 1 |
| Loiseau, P | 1 |
| Colburn, WA; Jack, ML | 1 |
| Finnerty, R; Goldberg, HL | 1 |
| Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI | 1 |
| Dvorchik, BH | 1 |
| Abdelmalik, OM; Airaudo, CB; Gayte-Sorbier, A; Guerri, J; Tchiakpé, L; Verdier, M | 1 |
| Airaudo, CB; Bianchi, C; Gayte-Sorbier, A; Verdier, M | 1 |
| Boothe, DM | 1 |
| Berman, ME; Taylor, SP; Weisman, AM | 1 |
| Carda-Broch, S; Esteve-Romero, J; García-Alvarez-Coque, MC; Gil-Agustí, M | 1 |
| Amano, K; Deshimaru, M; Katsuragi, S; Miyakawa, T; Miyazaki, C; Ogata, A; Takamatsu, J | 1 |
| Durand Alegría, JS; Fernández Hernando, P; Gil Tejedor, AM | 1 |
| O'Brien, GS; Plotnikoff, NP | 1 |
| Dervaux, A; Kanit, M; Laqueille, X; Launay, C | 1 |
| Bourgine, J; Coquerel, A; Freret, T; Lange, M; Lelong-Boulouard, V; Ma, LL | 1 |
13 review(s) available for clorazepate dipotassium and diazepam
| Article | Year |
|---|---|
Benzodiazepines and neurotic anxiety. Critique.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lethal Dose 50; Oxazepam; Psychiatric Status Rating Scales | 1976 |
Selection among benzodiazepines for alcohol withdrawal.
Topics: Administration, Oral; Benzodiazepines; Central Nervous System; Chlordiazepoxide; Clorazepate Dipotassium; Depression, Chemical; Diazepam; Drug Synergism; Ethanol; Half-Life; Humans; Oxazepam; Seizures; Substance Withdrawal Syndrome; Time Factors | 1977 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Pharmacokinetics in clinical medicine: oxazepam versus other benzodiazepines.
Topics: Administration, Oral; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Injections, Intravenous; Male; Mathematics; Models, Biological; Oxazepam; Time Factors | 1975 |
Review of the side-effect profile of buspirone.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Dizziness; Double-Blind Method; Drug Evaluation; Fatigue; Headache; Humans; Lorazepam; Pyrimidines | 1986 |
Use of barbiturates and benzodiazepines in treatment of epilepsy.
Topics: Adult; Barbiturates; Benzodiazepines; Child; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Lorazepam; Phenobarbital; Primidone | 1986 |
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Lorazepam; Maternal-Fetal Exchange; Nitrazepam; Oxazepam; Pregnancy | 1982 |
The use of benzodiazepines in clinical practice.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lorazepam; Metabolic Clearance Rate; Oxazepam; Prazepam; Substance Withdrawal Syndrome | 1981 |
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Kinetics; Lorazepam; Maternal-Fetal Exchange; Milk, Human; Nitrazepam; Oxazepam; Postpartum Period; Pregnancy | 1983 |
[The state of psychopharmacotherapy in geriatrics 2].
Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; Delirium; Dementia; Depression; Dextrans; Diazepam; Glucose; Humans; Imipramine; Nitrazepam; Oxygen Consumption; Paranoid Disorders; Promethazine; Psychotropic Drugs; Sleep Wake Disorders; Trimeprazine | 1980 |
[Benzodiazepines in the treatment of epilepsy].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child, Preschool; Clobazam; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy; Epilepsy, Temporal Lobe; Humans; Injections, Intravenous; Nitrazepam; Status Epilepticus; Suppositories | 1983 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature].
Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium; Comorbidity; Controlled Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; Euphoria; Flunitrazepam; Heroin Dependence; Humans; Metabolic Clearance Rate; Methadone; Narcotics; Substance-Related Disorders; Young Adult | 2009 |
31 trial(s) available for clorazepate dipotassium and diazepam
| Article | Year |
|---|---|
Clorazepate dipotassium (Tranxene): a controlled evaluation in alcoholic patients after withdrawal.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Middle Aged; Placebos; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome | 1976 |
Effect of N-desmethyldiazepam (nordiazepam) and a precursor, potassium clorazepate, on sleep in man.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Male; Nordazepam; Sleep; Sleep Stages; Time Factors | 1976 |
Benzodiazepines and neurotic anxiety. Critique.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lethal Dose 50; Oxazepam; Psychiatric Status Rating Scales | 1976 |
Residual effects of potassium clorazepate, a precursor of nordiazepam.
Topics: Adult; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Humans; Motor Skills; Placebos; Time Factors; Vision, Ocular | 1977 |
Effect of antacids on absorption of clorazepate.
Topics: Adult; Aluminum Hydroxide; Antacids; Anti-Anxiety Agents; Biopharmaceutics; Clorazepate Dipotassium; Diazepam; Half-Life; Humans; Magnesium Hydroxide; Male; Middle Aged; Oxazepam | 1977 |
Clorazepate: double blind crossover comparison of a single nightly dose with diazepam thrice daily in anxiety.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Humans; Male; Middle Aged; Placebos | 1977 |
A controlled comparative trial of clorazepate (Tranxene) and diazepam (Valium) for anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales | 1977 |
Impaired absorption of desmethyldiazepam from clorazepate by magnesium aluminum hydroxide.
Topics: Adult; Aged; Aluminum Hydroxide; Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Intestinal Absorption; Kinetics; Magnesium; Magnesium Hydroxide; Male; Middle Aged; Nordazepam; Time Factors | 1978 |
A double-blind comparison of prazepam with diazepam, chlorazepate dipotassium and placebo in anxious out-patients.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Drug Evaluation; Evaluation Studies as Topic; Humans; Middle Aged; Outpatients; Placebos; Prazepam; Sleep Stages | 1979 |
[Tranxillium 20 (dipotassium chlorazepate) as a 24-hr tranquilizer].
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Depression; Diazepam; Headache; Humans; Placebos; Sleep Wake Disorders | 1975 |
Clinical and experimental comparison of diazepam, chlorazepate and placebo.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Automobile Driving; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Galvanic Skin Response; Heart Rate; Humans; Motor Skills; Placebos; Respiration | 1975 |
Clinical and physiological assessment of chlorazepate, diazepam and placebo in anxious neurotics.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety Disorders; Arousal; Blood Pressure; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Female; Galvanic Skin Response; Heart Rate; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Reaction Time; Respiration | 1975 |
A single-dose anti-anxiety drug. A report from the General Practitioner Research Group.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Female; Humans; Libido; Male; Middle Aged | 1975 |
Review of the side-effect profile of buspirone.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Dizziness; Double-Blind Method; Drug Evaluation; Fatigue; Headache; Humans; Lorazepam; Pyrimidines | 1986 |
Influence of propranolol coadministration or cigarette smoking on the kinetics of desmethyldiazepam following intravenous clorazepate.
Topics: Adult; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Drug Interactions; Female; Humans; Infusions, Intravenous; Kinetics; Male; Metabolic Clearance Rate; Nordazepam; Propranolol; Smoking | 1986 |
Indications and contraindications for chronic anxiolytic treatment: is there tolerance to the anxiolytic effect?
Topics: Anxiety; Chronic Disease; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Drug Tolerance; Humans; Lorazepam; Substance Withdrawal Syndrome | 1985 |
Clinical and biochemical comparison of clorazepate and diazepam.
Topics: Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Outpatient Clinics, Hospital; Placebos; Self-Assessment; Structure-Activity Relationship | 1974 |
Physiological and psychological effects of clorazepate in man.
Topics: Adult; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Electroencephalography; Evoked Potentials; Flicker Fusion; Galvanic Skin Response; Humans; Male; Motor Skills; Reaction Time; Time Factors; Tremor | 1980 |
[Night-time premedication with Di-potassium-clorazepate, diazepam or a placebo before anaesthesia; a double-blind trial (author' transl)].
Topics: Adult; Anti-Anxiety Agents; Anxiety; Blood Pressure; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Heart Rate; Humans; Preanesthetic Medication; Sleep Stages | 1981 |
Steady-state plasma desmethyldiazepam during long-term clorazepate use: effects of antacids.
Topics: Adult; Aluminum Hydroxide; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Drug Combinations; Drug Interactions; Female; Gastric Acid; Humans; Magnesium; Magnesium Hydroxide; Male; Nordazepam; Time Factors | 1982 |
Desmethyldiazepam kinetics after intravenous, intramuscular, and oral administration of clorazepate dipotassium.
Topics: Administration, Oral; Adult; Aged; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Female; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Nordazepam | 1982 |
The value of anti-anxiety drugs in the management of cardiac disease.
Topics: Anti-Anxiety Agents; Antihypertensive Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Coronary Disease; Diazepam; Double-Blind Method; Female; Humans; Hypertension; Male; Verapamil | 1982 |
Value of a single night-time dose of potassium clorazepate in anxiety: a controlled trial comparison with diazepam.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Blood Pressure; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Nordazepam; Patient Compliance; Psychological Tests | 1982 |
The side effect profile of buspirone in comparison to active controls and placebo.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium; Depression; Diazepam; Double-Blind Method; Headache; Humans; Nausea; Placebos; Pyrimidines; Sleep Stages | 1982 |
Drug interactions in controlled clinical trials.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Drug Interactions; Drug Therapy, Combination; Humans; Placebos; Pyrimidines; Sleep Stages | 1982 |
[Comparative studies on the pharmacologic profile of Valium, Tranxilium and Dociton].
Topics: Adult; Anti-Anxiety Agents; Attention; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Humans; Male; Propranolol | 1983 |
Effects of clorazepate, diazepam, lorazepam, and placebo on human memory.
Topics: Administration, Oral; Adult; Amnesia; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lorazepam; Male; Memory; Mental Recall; Placebos | 1983 |
The role of general practitioner research groups in the study of benzodiazepines.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Family Practice; Half-Life; Humans; Lorazepam; Middle Aged; Sleep Initiation and Maintenance Disorders | 1983 |
Plasma concentrations and clinical effects after single oral doses of prazepam, clorazepate, and diazepam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Emotions; Female; Humans; Intestinal Absorption; Kinetics; Male; Nordazepam; Prazepam; Sleep | 1984 |
Comparison of buspirone in two separate studies.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium; Depression; Diazepam; Double-Blind Method; Female; Humans; Male; Personality Inventory; Psychiatric Status Rating Scales; Pyrimidines | 1982 |
Effects of clorazepate, diazepam, and oxazepam on a laboratory measurement of aggression in men.
Topics: Adult; Aggression; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Humans; Male; Oxazepam; Reaction Time | 1998 |
51 other study(ies) available for clorazepate dipotassium and diazepam
| Article | Year |
|---|---|
[Therapeutic notes: benzodiazepines].
Topics: Anti-Anxiety Agents; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; Nitrazepam; Oxazepam | 1976 |
Disposition of three benzodiazepines after single oral administration in man.
Topics: Administration, Oral; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Male; Oxazepam | 1977 |
Clinical implications of benzodiazepine pharmacokinetics.
Topics: Administration, Oral; Adult; Age Factors; Aged; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Humans; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Liver; Lorazepam; Medazepam; Oxazepam | 1977 |
Pharmacokinetics of N-desmethyldiazepam in healthy volunteers after single daily doses of dipotassium chlorazepate.
Topics: Adult; Anti-Anxiety Agents; Body Weight; Clorazepate Dipotassium; Diazepam; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Nordazepam | 1977 |
Determination of desmethyldiazepam in plasma by electron-capture GLC: application to pharmacokinetic studies of clorazepate.
Topics: Anti-Anxiety Agents; Chromatography, Gas; Clorazepate Dipotassium; Diazepam; Female; Humans; Kinetics; Nordazepam; Time Factors | 1978 |
[Interactions between alcohol, diazepam or clorazepate dipotassium and mepivacaine local anesthesia in rabbits].
Topics: Anesthesia, Local; Animals; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Drug Interactions; Ethanol; Mepivacaine; Rabbits | 1976 |
Pharmacokinetic understanding of antianxiety drug therapy.
Topics: Adult; Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Humans; Nordazepam; Oxazepam; Prazepam | 1978 |
Effects of some benzodiazepine derivatives on fibrinolysis and serum lipids in normolipidaemic rats and in humans.
Topics: Adult; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Cholesterol; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Female; Fibrinolysis; Humans; Lipids; Lorazepam; Male; Middle Aged; Rats; Triglycerides | 1978 |
Transfer in vitro of three benzodiazepines across the human placenta.
Topics: Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Female; Fetus; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy | 1979 |
Pharmacokinetics of the placental transfer and distribution of clorazepate and its metabolite nordiazepam in the feto-placental unit and in the neonate.
Topics: Adult; Amniotic Fluid; Anti-Anxiety Agents; Biotransformation; Clorazepate Dipotassium; Diazepam; Female; Fetus; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Placenta; Pregnancy; Time Factors | 1979 |
Effect of age and Billroth gastrectomy on absorption of desmethyldiazepam from clorazepate.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Female; Gastrectomy; Humans; Intestinal Absorption; Male; Middle Aged; Nordazepam | 1979 |
Serum diazepam concentrations in overdose. Their significance.
Topics: Alcohol Drinking; Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Clorazepate Dipotassium; Coma; Diazepam; Humans; Spectrophotometry | 1979 |
Self-rated sedation and plasma concentrations of desmethyldiazepam following single doses of clorazepate.
Topics: Adult; Aged; Anti-Anxiety Agents; Biotransformation; Clorazepate Dipotassium; Diazepam; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nordazepam | 1979 |
Benzodiazepines: some aspects of their clinical pharmacology.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Lorazepam; Oxazepam; Prazepam | 1979 |
GLC determination of plasma drug levels after oral administration of clorazepate potassium salts.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Biological Availability; Chromatography, Gas; Clorazepate Dipotassium; Diazepam; Dogs; Female; Time Factors | 1975 |
Behavioural and pharmacokinetic studies in the monkey (Macaca mulatta) with diazepam, nordiazepam and related 1,4-benzodiazepines.
Topics: Animals; Behavior, Animal; Clorazepate Dipotassium; Diazepam; Discrimination, Psychological; Half-Life; Haplorhini; Kinetics; Macaca mulatta; Male; Time Factors | 1977 |
A guide to the use of hypnotic drugs.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Flurazepam; Humans; Hypnotics and Sedatives; Sleep Wake Disorders; Substance-Related Disorders | 1979 |
Thin-layer detection of diazepam and/or chilordiazepoxide alone or in combination with major drugs of abuse in drug abuse urine screening programs.
Topics: Chlordiazepoxide; Chromatography, Thin Layer; Clorazepate Dipotassium; Diazepam; Humans; Indicators and Reagents; Mass Screening; Oxazepam; Substance-Related Disorders | 1978 |
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione | 1975 |
"Paradoxical rage reactions" during psychotropic medication.
Topics: Adult; Aggression; Anger; Child; Clorazepate Dipotassium; Diazepam; Ethanol; Female; Humans; Individuality; Male; Oxazepam; Psychotropic Drugs; Rage | 1975 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; Lorazepam; Meperidine; Midazolam; Morphine; Oxazepam; Pain; Pentazocine; Pirinitramide; Preanesthetic Medication | 1991 |
Intramuscular bioavailability of chlorazepate as compared to diazepam.
Topics: Adult; Anti-Anxiety Agents; Biological Availability; Clorazepate Dipotassium; Diazepam; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male | 1985 |
Treatment of episodic behavioral disorders with rapidly absorbed benzodiazepines.
Topics: Administration, Oral; Adult; Aggression; Anger; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Female; Humans; Kinetics; Male; Mental Disorders; Rage; Seizures; Triazolam | 1985 |
Drugs in dentistry. Agents for anxiety disorders.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Dental Care; Diazepam; Humans; Oxazepam | 1985 |
Chronic use of benzodiazepines and psychomotor and cognitive test performance.
Topics: Adult; Affect; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Clorazepate Dipotassium; Cognition Disorders; Diazepam; Female; Flicker Fusion; Humans; Lorazepam; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Psychomotor Disorders | 1986 |
Desmethyldiazepam pharmacokinetics: studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam.
Topics: Administration, Oral; Adult; Aged; Anti-Anxiety Agents; Biological Availability; Clorazepate Dipotassium; Diazepam; Female; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Nordazepam | 1988 |
Monitoring clorazepate dipotassium as desmethyldiazepam in plasma by electron-capture gas--liquid chromatography.
Topics: Anti-Anxiety Agents; Chromatography, Gas; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Humans; Nordazepam | 1980 |
[Benzodiazepines and limbic system. Anxiety and vigilance (author's transl)].
Topics: Animals; Anti-Anxiety Agents; Arousal; Behavior, Animal; Cats; Circadian Rhythm; Clorazepate Dipotassium; Diazepam; Electroencephalography; Hippocampus; Humans; Limbic System; Lorazepam; Nitrazepam; Sleep | 1980 |
Pharmacokinetics of N-desmethyldiazepam after a single oral dose of clorazepate: the effect of smoking.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Male; Nordazepam; Smoking | 1981 |
Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Biotransformation; Clorazepate Dipotassium; Diazepam; Female; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Nordazepam; Sex Factors | 1981 |
[Anxiolytics in man: studies on sleep and performance (author's transl)].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Arousal; Attention; Benzodiazepines; Benzodiazepinones; Clobazam; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Humans; Motor Skills; Nordazepam; Sleep Stages; Visual Perception | 1982 |
Limited in vivo bioassays on some benzodiazepines: lack of experimental initiating or promoting effect of the benzodiazepine tranquillizers diazepam, clorazepate, oxazepam and lorazepam.
Topics: 2-Acetylaminofluorene; Animals; Anti-Anxiety Agents; Biological Assay; Carcinogens; Clorazepate Dipotassium; Diazepam; Lorazepam; Male; Oxazepam; Rats; Rats, Inbred F344; Time Factors | 1982 |
Attenuation of drug-induced anxiety dreams and pavor nocturnus by benzodiazepines.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Anxiety; Clorazepate Dipotassium; Diazepam; Female; Humans; Male; Sleep Wake Disorders | 1983 |
High-performance liquid chromatography determination of dipotassium clorazepate and its major metabolite nordiazepam in plasma.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Clorazepate Dipotassium; Diazepam; Dogs; Half-Life; Humans; Kinetics; Nordazepam | 1983 |
Effects of benzodiazepines on digoxin tissue concentrations and plasma protein binding.
Topics: Animals; Anti-Anxiety Agents; Blood Proteins; Clorazepate Dipotassium; Diazepam; Digoxin; Dogs; Drug Interactions; Humans; In Vitro Techniques; Protein Binding | 1983 |
In vitro effect of benzodiazepines on polymorphonuclear leukocyte oxidative activity.
Topics: Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; In Vitro Techniques; Lymphocyte Activation; Neutrophils; Nitroblue Tetrazolium; Oxygen Consumption; Stimulation, Chemical; Zymosan | 1984 |
Clorazepate dipotassium and diazepam in renal insufficiency: serum concentrations and protein binding of diazepam and desmethyldiazepam.
Topics: Adult; Aged; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Nordazepam; Protein Binding | 1984 |
The effects of benzodiazepines on hormones in women with idiopathic hirsutism.
Topics: Adult; Androgens; Androstenedione; Anti-Anxiety Agents; Clorazepate Dipotassium; Dehydroepiandrosterone; Diazepam; Female; Hirsutism; Humans; Sex Hormone-Binding Globulin; Testosterone | 1984 |
Comparative single-dose kinetics of oxazolam, prazepam, and clorazepate: three precursors of desmethyldiazepam.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clorazepate Dipotassium; Diazepam; Female; Humans; Kinetics; Male; Molecular Weight; Nordazepam; Prazepam | 1984 |
Antiepileptic effect and serum levels of clorazepate on children with refractory seizures.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Child; Child, Preschool; Clorazepate Dipotassium; Diazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Infant; Nordazepam; Spasms, Infantile | 1984 |
Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration.
Topics: Adult; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Male; Models, Biological; Nordazepam | 1983 |
Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).
Topics: Adult; Aged; Body Weight; Clorazepate Dipotassium; Diazepam; Female; Half-Life; Humans; Male; Middle Aged; Nordazepam; Obesity | 1982 |
Drug disposition during pregnancy.
Topics: Anti-Bacterial Agents; Clorazepate Dipotassium; Diazepam; Digoxin; Female; Furosemide; Humans; Kidney; Kinetics; Lithium; Liver; Meperidine; Pharmaceutical Preparations; Phenytoin; Pregnancy | 1982 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; Medazepam; Nitrazepam; Oxazepam; Safety; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam; Triazolam | 1980 |
Stedim 6 and Clearflex, two new multilayer materials for infusion containers. Comparative study of their compatibility with five drugs versus glass flasks and polyvinyl chloride bags.
Topics: Adsorption; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clodronic Acid; Clorazepate Dipotassium; Diazepam; Glass; Infusion Pumps; Maprotiline; Polyethylenes; Polyvinyl Chloride; Silicates; Structure-Activity Relationship | 1995 |
Interactions between six psychotherapeutic drugs and plastic containers. Influence of plastic material and infusion solutions.
Topics: Chlorpromazine; Clomipramine; Clorazepate Dipotassium; Diazepam; Humans; Infusions, Parenteral; Maprotiline; Polyethylenes; Polyvinyl Chloride; Psychotropic Drugs; Viloxazine | 1993 |
Use of micellar mobile phases for the chromatographic determination of clorazepate, diazepam, and diltiazem in pharmaceuticals.
Topics: Calibration; Chromatography, Liquid; Clorazepate Dipotassium; Diazepam; Diltiazem; Micelles; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet | 2000 |
Differences between the tolerance characteristics of two anticonvulsant benzodiazepines in the amygdaloid-kindled rat.
Topics: Amygdala; Animals; Anticonvulsants; Clorazepate Dipotassium; Diazepam; Drug Tolerance; Electric Stimulation; Evoked Potentials; Injections, Intraperitoneal; Kindling, Neurologic; Male; Rats; Rats, Wistar; Seizures; Time Factors | 2001 |
A rapid fluorimetric screening method for the 1,4-benzodiazepines: determination of their metabolite oxazepam in urine.
Topics: Clorazepate Dipotassium; Diazepam; Humans; Oxazepam; Sensitivity and Specificity; Spectrometry, Fluorescence | 2007 |
Comparison of anticonvulsant effects of clorazepate dipotassium and diazepam. Four week anticonvulsant study in Rhesus monkeys.
Topics: Animals; Anticonvulsants; Clorazepate Dipotassium; Convulsants; Diazepam; Macaca mulatta; Pentylenetetrazole; Seizures; Time Factors; Treatment Outcome | 1974 |
Benzodiazepines increase the reward effects of buprenorphine in a conditioned place preference test in the mouse.
Topics: Amphetamine; Animals; Bromazepam; Buprenorphine; Clorazepate Dipotassium; Conditioning, Psychological; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Reward | 2014 |