clopidogrel and vorapaxar

clopidogrel has been researched along with vorapaxar in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's17 (73.91)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Akram, F; Akram, S; Postuła, M1
Colombo, A; Merlini, P1
Butt, M; Lip, GY; Shantsila, E; Siddique, A1
Banach, M; Hannam, S; Kowalczyk, M; Mikhailidis, DP; Rysz, J1
del Río, A; Heras, M1
Jilma, B; Krumphuber, J; Siller-Matula, JM1
Goto, S; Ikeda, Y; Jensen, P; Kato, K; Yamaguchi, H; Yamaguchi, T1
Diener, HC; Weber, R1
Pollack, CV1
Ağırbaşlı, M; Cinçin, A; Güvenç, H1
White, HD1
Armstrong, PW; Aylward, PE; Chen, E; Cornel, JH; Harrington, RA; Held, C; Huang, Z; Jennings, LK; Lokhnygina, Y; Mahaffey, KW; Moliterno, DJ; Strony, J; Tricoci, P; Van de Werf, F; Wallentin, L; White, HD1
Cai, TQ; Chintala, M; Forrest, M; Handt, L; Michener, MS; Raubertas, R; Seiffert, D; Sitko, G; Wickham, LA1
Serebruany, VL1
Arif, SA; D'Souza, J; Gil, M; Gim, S1
Akins, S; Bhal, V; Dixon, M; Herr, MJ; Hord, E; Jennings, LK; Kotha, J; Seiffert, D; White, MM1
Kim, MH; Pokov, AN; Serebruany, VL; Tomek, A1
Cabrera-Fuentes, HA; Cherepanov, V; Kim, MH; Serebruany, VL1
Can, M; Fortmann, SD; Hanley, DF; Kim, MH; Lordkipanidze, M; Marciniak, TA; Rao, SV; Serebruany, VL; Tanguay, JF1
Bekbossynova, M; Cattaneo, M; Golukhova, E; Kim, MH; Marciniak, TA; Pya, Y; Serebruany, VL1
Bash, LD; Davies, G; Du, M; Oguz, M; Ozer-Stillman, I; Whalen, JD1
Chase, M; Davies, G; Du, M; Oguz, M1
Aedma, SK; Combs, WG; Gupta, R; Kluck, B; Lin, M; Mehta, A; Patel, NC; Ranchal, P; Shah, R; Singh, S; Vyas, AV1

Reviews

12 review(s) available for clopidogrel and vorapaxar

ArticleYear
Current problems, new opportunities and future directions of anti-platelet therapy - increasing role of novel antiplatelet agents in cardiovascular diseases.
    Recent patents on cardiovascular drug discovery, 2009, Volume: 4, Issue:1

    Topics: Adenosine; Adenosine Monophosphate; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Imines; Lactones; Patents as Topic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thiophenes; Ticagrelor; Ticlopidine

2009
New antiplatelet drugs: beyond aspirin and clopidogrel.
    International journal of clinical practice, 2009, Volume: 63, Issue:5

    Topics: Adenosine; Adenosine Monophosphate; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Imines; Lactones; Naphthalenes; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Propionates; Purinergic P2 Receptor Antagonists; Pyridines; Thiophenes; Ticagrelor; Ticlopidine

2009
Ticagrelor--a new platelet aggregation inhibitor in patients with acute coronary syndromes. An improvement of other inhibitors?
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:12

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Biotransformation; Clinical Trials as Topic; Clopidogrel; Hemorrhage; Humans; Lactones; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine

2009
Update on antiplatelet therapy in acute coronary syndromes: what do new drugs bring into clinical practice?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2009, Volume: 9 Suppl 1

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticagrelor; Ticlopidine

2009
Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Benzofurans; Blood Platelets; Carbamates; Clinical Trials as Topic; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Receptor, PAR-1; Receptors, Proteinase-Activated; Thiophenes; Ticagrelor; Ticlopidine; von Willebrand Factor

2010
Controversies and future perspectives of antiplatelet therapy in secondary stroke prevention.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10

    Topics: Aspirin; Blood-Brain Barrier; Cilostazol; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Humans; Lactones; Naphthalenes; Platelet Aggregation Inhibitors; Propionates; Pyridines; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Succinates; Tetrazoles; Thrombosis; Ticlopidine

2010
[Novel agents in antiplatelet therapy].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2010, Volume: 38, Issue:5

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Pyridines; Receptors, Thrombin; Thiophenes; Ticagrelor; Ticlopidine

2010
Vorapaxar for reduction of thrombotic cardiovascular events in myocardial infarction and peripheral artery disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Oct-01, Volume: 72, Issue:19

    Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Half-Life; Hemorrhage; Humans; Lactones; Myocardial Infarction; Myocardial Ischemia; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptor, PAR-1; Secondary Prevention; Stroke; Thrombosis; Ticlopidine

2015
Clopidogrel, prasugrel, ticagrelor or vorapaxar in patients with renal impairment: do we have a winner?
    Expert review of cardiovascular therapy, 2015, Volume: 13, Issue:12

    Topics: Acute Coronary Syndrome; Adenosine; Clinical Trials as Topic; Clopidogrel; Comparative Effectiveness Research; Glomerular Filtration Rate; Hemorrhage; Humans; Lactones; Patient Selection; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Renal Insufficiency; Ticagrelor; Ticlopidine

2015
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
    Thrombosis and haemostasis, 2015, Nov-25, Volume: 114, Issue:6

    Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopidogrel; Colonic Neoplasms; Drug Therapy, Combination; Female; Humans; Lactones; Male; Mice; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Randomized Controlled Trials as Topic; Rivaroxaban; Sex Factors; Species Specificity; Ticagrelor; Ticlopidine; Time Factors

2015
Vorapaxar and diplopia: Possible off-target PAR-receptor mismodulation.
    Thrombosis and haemostasis, 2016, 05-02, Volume: 115, Issue:5

    Topics: Animals; Aspirin; Clopidogrel; Diplopia; Drug Approval; Eye; Humans; Lactones; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptor, PAR-1; Receptors, Proteinase-Activated; Ticlopidine; United States; United States Food and Drug Administration

2016
Protease-Activated Receptor Antagonist for Reducing Cardiovascular Events - A Review on Vorapaxar.
    Current problems in cardiology, 2023, Volume: 48, Issue:3

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Receptors, Proteinase-Activated; Stroke; Treatment Outcome

2023

Trials

2 trial(s) available for clopidogrel and vorapaxar

ArticleYear
Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome.
    Journal of atherosclerosis and thrombosis, 2010, Feb-26, Volume: 17, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Double-Blind Method; Female; Heparin; Humans; Japan; Lactones; Male; Middle Aged; Placebos; Pyridines; Receptor, PAR-1; Ticlopidine

2010
Vorapaxar with or without clopidogrel after non-ST-segment elevation acute coronary syndromes: results from the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome trial.
    American heart journal, 2014, Volume: 168, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Electrocardiography; Female; Hemorrhage; Humans; Lactones; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Secondary Prevention; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome

2014

Other Studies

9 other study(ies) available for clopidogrel and vorapaxar

ArticleYear
The ischaemia/bleeding balance in PCI.
    Lancet (London, England), 2009, Mar-14, Volume: 373, Issue:9667

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Lactones; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptors, Thrombin; Severity of Illness Index; Thrombin; Ticlopidine

2009
Emerging oral antiplatelet therapies for acute coronary syndromes.
    Hospital practice (1995), 2010, Volume: 38, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Aspirin; Cardiology; Clopidogrel; Drug Therapy, Combination; Emergency Medicine; Hemorrhage; Hospitalists; Humans; Imines; Lactones; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; Pyridines; Receptor, PAR-1; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome

2010
Oral antiplatelet therapy for atherothrombotic disease: current evidence and new directions.
    American heart journal, 2011, Volume: 161, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Lactones; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyridines; Quinazolinones; Randomized Controlled Trials as Topic; Receptor, PAR-1; Sulfonamides; Ticagrelor; Ticlopidine

2011
Platelet transfusion reverses bleeding evoked by triple anti-platelet therapy including vorapaxar, a novel platelet thrombin receptor antagonist.
    European journal of pharmacology, 2015, Jul-05, Volume: 758

    Topics: Animals; Aspirin; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Lactones; Macaca fascicularis; Platelet Aggregation Inhibitors; Platelet Transfusion; Pyridines; Receptors, Thrombin; Ticlopidine

2015
Redesigning TRACER trial after TRITON.
    International journal of cardiology, 2015, Oct-15, Volume: 197

    Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Evaluation; Drug Therapy, Combination; Hemorrhage; Humans; Lactones; Neoplasms; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Research Design; Ticlopidine

2015
Platelet function recovery following exposure to triple anti-platelet inhibitors using an in vitro transfusion model.
    Thrombosis research, 2015, Volume: 136, Issue:6

    Topics: Apoptosis Regulatory Proteins; Arachidonic Acid; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Flow Cytometry; Hemorrhage; Humans; Lactones; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Purinergic P2Y Receptor Antagonists; Pyridines; Receptors, Proteinase-Activated; Receptors, Purinergic P2Y12; Ticlopidine

2015
Continued vorapaxar versus withdrawed clopidogrel both on top of low dose aspirin in patients undergoing heart surgery: A call for randomized trial.
    International journal of cardiology, 2016, Jul-15, Volume: 215

    Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Lactones; Male; Myocardial Infarction; Postoperative Hemorrhage; Pyridines; Survival Analysis; Ticlopidine; Treatment Outcome

2016
A State Transition Model for Health Outcomes Associated with Vorapaxar Treatment as an Add-on to Standard Care Antiplatelet Therapy in the Prevention of Thrombotic Events for Patients with a Recent Myocardial Infarction.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:4

    Topics: Aspirin; Cardiovascular System; Clopidogrel; Hemorrhage; Humans; Lactones; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Secondary Prevention; Stroke; Thrombosis; Ticlopidine; Treatment Outcome

2016
State transition model: vorapaxar added to standard antiplatelet therapy to prevent thrombosis post myocardial infarction or peripheral artery disease.
    Current medical research and opinion, 2017, Volume: 33, Issue:9

    Topics: Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Lactones; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Quality of Life; Quality-Adjusted Life Years; Secondary Prevention; Stroke; Thrombosis; Ticlopidine

2017