clopidogrel and thromboxane a2

clopidogrel has been researched along with thromboxane a2 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, HV; Benedict, CR; Buja, LM; Campbell, WB; Cui, K; Maffrand, JP; McNatt, J; Ober, JC; Rosolowsky, M; Yao, SK1
Ishihara, H; Kawai, H; Nakashima, M; Umemura, K1
Anderson, HV; Buja, LM; Cui, K; Maffrand, JP; McNatt, J; Willerson, JT; Yao, SK1
Antman, EM; Wiviott, SD1
Garcia, A; Kim, S; Kunapuli, SP; Prabhakar, J; Shankar, H1
Barst, RJ; Christman, BW; Cunningham, G; Kawut, SM; Kimmel, SE; Lloyd, W; Loscalzo, J; Reilly, MP; Robbins, IM; Yung, D1
Fitzgerald, DJ; Maree, AO1
Alberts, P; Bounameaux, H; Fontana, P; Mann, J; Sakariassen, KS; Sorensen, AS1
Armstrong, PC; Dhanji, AR; Mitchell, JA; Tucker, AT; Warner, TD1
Aylward, PE; Behan, MW; Chew, DP1
Coimbra, LS; Gerlach, RF; GuimarĂ£es, MR; Herrera, BS; MuscarĂ¡, MN; Rossa, C; Spolidorio, DM; Spolidorio, LC1
Al-Asady, N; Caro, J; Clavijo, LC; Dhillon, A; Matthews, RV; Rowe, V; Shavelle, DM; Tun, H1

Reviews

3 review(s) available for clopidogrel and thromboxane a2

ArticleYear
Variable platelet response to aspirin and clopidogrel in atherothrombotic disease.
    Circulation, 2007, Apr-24, Volume: 115, Issue:16

    Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Biomarkers; Biotransformation; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resistance; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Thromboxane A2; Thromboxane B2; Ticlopidine; Treatment Failure

2007
Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases.
    Future cardiology, 2009, Volume: 5, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Humans; Kidney Diseases; Platelet Aggregation Inhibitors; Proteinuria; Receptors, Thrombin; Thrombosis; Thromboxane A2; Thromboxane-A Synthase; Ticlopidine

2009
The role of antiplatelet therapy in the secondary prevention of coronary artery disease.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Secondary Prevention; Thiophenes; Thromboxane A2; Ticagrelor; Ticlopidine

2010

Trials

2 trial(s) available for clopidogrel and thromboxane a2

ArticleYear
A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension.
    The European respiratory journal, 2006, Volume: 27, Issue:3

    Topics: Adult; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; Ticlopidine

2006
Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aspirin; Blood Platelets; Clopidogrel; Down-Regulation; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thromboxane A2; Thromboxane B2; Ticlopidine; Young Adult

2010

Other Studies

7 other study(ies) available for clopidogrel and thromboxane a2

ArticleYear
ADP plays an important role in mediating platelet aggregation and cyclic flow variations in vivo in stenosed and endothelium-injured canine coronary arteries.
    Circulation research, 1992, Volume: 70, Issue:1

    Topics: Adenosine Diphosphate; Animals; Apyrase; Bridged Bicyclo Compounds, Heterocyclic; Clopidogrel; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Thromboxane A2; Ticlopidine

1992
Inhibitory effect of clopidogrel, vapiprost and argatroban on the middle cerebral artery thrombosis in the rat.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:3

    Topics: Animals; Arginine; Biphenyl Compounds; Cerebral Arteries; Cerebrovascular Circulation; Clopidogrel; Fibrinolytic Agents; Heptanoic Acids; Intracranial Embolism and Thrombosis; Male; Photic Stimulation; Pipecolic Acids; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Receptors, Thromboxane; Regional Blood Flow; Sulfonamides; Thromboxane A2; Ticlopidine

1995
Combined ADP and thromboxane A2 antagonism prevents cyclic flow variations in stenosed and endothelium-injured arteries in nonhuman primates.
    Circulation, 1993, Volume: 88, Issue:6

    Topics: Adenosine Diphosphate; Animals; Clopidogrel; Constriction, Pathologic; Coronary Vessels; Dogs; Endothelium, Vascular; Female; Femoral Artery; Hemodynamics; Humans; In Vitro Techniques; Papio; Platelet Aggregation; Regional Blood Flow; Thromboxane A2; Ticlopidine

1993
Clopidogrel resistance: a new chapter in a fast-moving story.
    Circulation, 2004, Jun-29, Volume: 109, Issue:25

    Topics: Angioplasty; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Eptifibatide; Heparin; Humans; Peptides; Platelet Aggregation Inhibitors; Stents; Thromboxane A2; Ticlopidine; Treatment Outcome

2004
P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:3

    Topics: Adenosine Monophosphate; Animals; Blood Platelets; Butadienes; Clopidogrel; Enzyme Inhibitors; Humans; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Nitriles; Phospholipases A; Phospholipases A2; Platelet Aggregation Inhibitors; Pyrimidines; Receptor, PAR-1; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Signal Transduction; src-Family Kinases; Thrombin; Thromboxane A2; Ticlopidine

2006
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
    Journal of periodontology, 2011, Volume: 82, Issue:5

    Topics: Alveolar Bone Loss; Animals; Aspirin; Blood Platelets; Bone Density; Bone Regeneration; Clopidogrel; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Interleukin-6; Leukocytes; Male; Mandibular Diseases; Periodontal Attachment Loss; Periodontitis; Periodontium; Platelet Activation; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Ticlopidine; Time Factors; Tumor Necrosis Factor-alpha; Wound Healing; X-Ray Microtomography

2011
Prevalence of high on-treatment (aspirin and clopidogrel) platelet reactivity in patients with critical limb ischemia.
    Cardiovascular revascularization medicine : including molecular interventions, 2018, Volume: 19, Issue:5 Pt A

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Critical Illness; Drug Therapy, Combination; Female; Humans; Ischemia; Male; Microfilament Proteins; Middle Aged; Peripheral Arterial Disease; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thromboxane A2; Time Factors; Treatment Outcome

2018