clopidogrel and thienopyridine

clopidogrel has been researched along with thienopyridine in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's56 (60.87)29.6817
2010's36 (39.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cannon, C1
Berger, PB; Lubbe, DF1
Brinkman, WT; Chaikof, EL; Najibi, S; Terramani, TT1
Blanchard, D; Danchin, N; Demicheli, T1
Tendera, M; Wojakowski, W1
Rodgers, JE; Steinhubl, SR1
Ajani, AE; Waksman, R1
Jacobson, AK1
Bennett, SK; Redberg, RF1
Cattaneo, M1
Berger, P; Grines, C; Harrington, RA; Ohman, EM; Popma, JJ; Weitz, JI1
Ferguson, JJ; Kadakia, RA1
Ambrosini, V; Bolognese, L; Bongo, AS; Gaglione, A; Galassi, AR; Marzocchi, A; Petronio, AS; Savonitto, S; Tolaro, S1
Gachet, C; Hechler, B1
Herbert, JM; Savi, P1
Asai, F; Jakubowski, JA; Niitsu, Y; Sugidachi, A1
Agostoni, P; Airoldi, F; Barbagallo, R; Biondi-Zoccai, GG; Briguori, C; Carlino, M; Chieffo, A; Colombo, A; Falchetti, E; Iakovou, I; Margheri, M; Melzi, G; Michev, I; Montorfano, M; Remigi, E; Sangiorgi, GM; Tamburino, C; Tsagalou, E; Vittori, G1
Antman, EM; Behounek, BD; Braunwald, E; Carney, RJ; Lazzam, C; McCabe, CH; McKay, RG; Murphy, SA; Weerakkody, G; Winters, KJ; Wiviott, SD1
Andre, P; Conley, PB; Phillips, DR; Sinha, U1
Bucha, E; Nowak, G; Schumann, A1
Behar, S; Gottlieb, S; Hammerman, H; Hasdai, D; Hod, H; Iakobishvili, Z; Konstantino, Y; Porter, A; Sandach, A; Zahger, D1
Abbate, A; Agostoni, P; Biondi-Zoccai, GG; Sangiorgi, GM; Valgimigli, M1
Bach, RG; Cohen, DJ; Decker, C; Jones, PG; Kettelkamp, R; Khanal, S; Krumholz, HM; Messenger, JC; Peterson, ED; Rumsfeld, JS; Spertus, JA; Vance, C1
Cofta, S; Elikowski, W; Mańczak, J; Nowicki, A; Psuja, P1
Gurbel, PA; Tantry, US; Wiviott, SD1
Bliden, KP; Gurbel, PA; Tantry, US1
Campbell, ME; Dery, JP; Gibson, CM; Harrington, RA; Madan, M; Mathias, J; O'Shea, JC; Pieper, KS; Tcheng, JE; Tolleson, TR1
Huber, K; Schrör, K; Siller-Matula, J; Wojta, J1
Hamdalla, H; Steinhubl, SR1
Bavry, AA; Bhatt, DL1
Bandarenko, N; Bennett, CL; Buffie, CG; Cursio, JF; Davidson, C; De Masi, D; Fujimura, Y; Kato, S; Kim, B; Kiss, JE; Kwaan, HC; Matsumoto, M; McKoy, JM; Ortel, TL; Pandey, DK; Raife, TJ; Raisch, DW; Sadler, JE; Sarode, R; Tevar, AD; Uemura, M; Yarnold, PR; Zakarija, A; Zheng, XL1
Banares, M; Gollapudi, RR; Lee, SS; Price, MJ; Sawhney, N; Schatz, RA; Teirstein, PS; Valencia, R; Wong, GB1
Alfonso, F; Angiolillo, DJ1
Boden, WE; Hoekstra, J; Miller, CD1
Casterella, PJ; Tcheng, JE1
Choi, SH; Prasad, A; Tsimikas, S1
Klauss, V; Krötz, F; Sohn, HY1
Brandt, JT; Braun, OO; Erlinge, D; Jakubowski, JA; James, S; Siegbahn, A; Sugidachi, A; Varenhorst, C; Wallentin, L; Winters, KJ1
Cairns, JA; Eikelboom, J1
Farid, NA; Hagihara, K; Ikeda, T; Kazui, M; Kurihara, A; Nishiya, Y1
Barragan, P; Bonello, L; Camoin-Jau, L; De Labriolle, A; Dignat-George, F; Lemesle, G; Paganelli, F; Pakala, R; Pichard, AD; Pinto Slottow, TL; Roy, P; Scheinowitz, M; Steinberg, DH; Waksman, R1
Holmes, DR; Prasad, A1
Das, K; Das, P; Koshy, SK; Robinson, A1
Makarov, LM; Serebruany, VL1
Harrington, RA; Sellers, MB; Tricoci, P1
Wallentin, L1
Lovric, D; Milicic, D; Skoric, B1
Kumar, A; Roberts, DH1
Berntsson, P; Björkman, JA; van Giezen, JJ; Zachrisson, H1
Farid, NA; Hagihara, K; Honda, K; Ikeda, T; Kazui, M; Kurihara, A; Okazaki, O; Yoshiike, M1
Kastrati, A; Sibbing, D1
Antman, EM; Bates, ER; Braunwald, E; Close, SL; Hautvast, RW; Mega, JL; Michelson, AD; Murphy, SA; O'Donoghue, ML; Rozenman, Y; Sabatine, MS; Shen, L; Ver Lee, PN; Wiviott, SD1
Avsar, O; Batyraliev, TA; Islek, M; Preobrazhenskiĭ, DV; Sidorenko, BA; Vural, A1
Goto, S; Toda, E1
Farid, NA; Kurihara, A; Wrighton, SA1
Avsar, O; Batyraliev, TA; Fettser, DV; Islek, M; Preobrazhenskiĭ, DV; Sidorenko, BA; Vural, A1
Jilma, B; Krumphuber, J; Siller-Matula, JM1
Steinhubl, SR1
Solomon, S; Vacek, JL1
Gurbel, PA; Tantry, US1
Ebina, T; Hashiba, K; Hibi, K; Iwahashi, N; Kimura, K; Kosuge, M; Maejima, N; Morita, S; Nakachi, T; Ohtsuka, F; Okuda, J; Sugano, T; Tahara, Y; Tsukahara, K; Umemura, S1
Islam, AM; Patel, PM1
Chew, DP; Prakash, R; Wong, YW1
Angiolillo, DJ; Vivas, D1
Le Lorier, J; Potter, BJ1
Gurbel, PA; Mahla, E; Metzler, H; Tantry, US1
Batyraliev, TA; Besnili, F; Fettser, DV; Niiazova-Karben, ZA; Preobrazhenskiĭ, DV; Sidorenko, BA1
Marcucci, R1
Fujita, M; Haruma, K; Honda, K; Ishii, M; Kamada, T; Matsumoto, H; Murao, T; Sakakibara, T; Shiotani, A; Tarumi, K1
Fantoni, C; Inglese, L1
Caglayan, E; Er, F; Erdmann, E; Gassanov, N1
Collet, JP; Hulot, JS; Montalescot, G1
Abe, M; Araki, M; Byrne, RA; Ehara, N; Eizawa, H; Fujiwara, H; Furukawa, Y; Inada, T; Iwabuchi, M; Kaburagi, S; Kadota, K; Kastrati, A; Kimura, T; Kita, T; Mitsudo, K; Mitsuoka, H; Mizoguchi, T; Morimoto, T; Nakagawa, Y; Nakano, A; Natsuaki, M; Nobuyoshi, M; Nohara, R; Shiomi, H; Shizuta, S; Suwa, S; Tada, T; Takizawa, A; Taniguchi, R; Tazaki, J1
Cho, KI; Jang, JS; Je, HG; Jeong, YH; Jin, HY; Kim, BH; Kim, DI; Kim, DK; Kim, DS; Kim, WJ; Lee, JY; Lee, SW; Park, YH; Seo, JS; Seol, SH; Yang, TH1
Abtan, J; Aubry, P; Barthélémy, O; Belle, L; Beygui, F; Boueri, Z; Carrié, D; Cayla, G; Collet, JP; Cuisset, T; Elhadad, S; Henry, P; Kerneis, M; Monségu, J; Montalescot, G; Motreff, P; O'Connor, SA; Pouillot, C; Rangé, G; Rousseau, H; Sabouret, P; Saint-Etienne, C; Silvain, J; Van Belle, E; Vicaut, E1
Henderson, SO; Levine, M; Markland, FS; McCormick, T; Swenson, S; Thomas, SH1
Fareed, J; Jeske, W; Thethi, I1
Beigel, R; Elian, D; Fefer, P; Fink, N; Guetta, V; Hod, H; Matetzky, S; Novikov, I; Rosenberg, N; Segev, A1
Angiolillo, DJ; Braun, OÖ; Costigan, TM; Duvvuru, S; Effron, MB; Ferreiro, JL; Jakubowski, JA; Kleiman, NS; Saucedo, JF; Sundseth, S; Varenhorst, C; Walker, JR; Winters, KJ1
Chua, D; Nishi, C1
Becker, RC; Breithardt, G; Califf, RM; Fox, KA; Goodman, SG; Hacke, W; Halperin, JL; Hankey, GJ; Mahaffey, KW; Nessel, CC; Patel, MR; Piccini, JP; Singer, DE; Stevens, SR; White, HD1
Angiolillo, DJ; Baker, BA; Heiselman, DE; Jakubowski, JA; Li, W; Price, MJ1
Hartung, P; Hill, K; Schaefer, M; Schulze, A1
Alexander, KP; Li, S; Magid, DJ; Peterson, ED; Roe, MT; Ting, HH; Wang, TY1
Anderson, RA; Bundhoo, S; James, PE1
Chen, L; Liu, D; Liu, Y; Tao, Z; Xia, G; Zhi, S1
Ansell, J; Chang, P; Fonarow, GC; Gersh, BJ; Go, AS; Hylek, EM; Kowey, P; Lopes, RD; Mahaffey, KW; Peterson, ED; Piccini, JP; Rao, M; Simon, DN; Singer, DE; Thomas, L1
Ebina, T; Hibi, K; Imoto, K; Karube, N; Kimura, K; Nagashima, Z; Tsukahara, K; Uchida, K; Umemura, S1
Ann, SH; Cho, YR; De Jin, C; Guo, LZ; Kim, MH; Lee, MS; Park, JS; Park, K; Park, TH; Serebruany, VL; Shin, ES1
Haag, E; Lee, MS; Pollack, S; Reichek, N; Santiago, L; Shlofmitz, E; Shlofmitz, RA1
Barbato, E; Bartunek, J; Bressi, E; Bruyne, B; Di Gioia, G; Di Serafino, L; Mangiacapra, F; Morisco, C; Peace, AJ; Pellicano, M; Wijns, W1

Reviews

41 review(s) available for clopidogrel and thienopyridine

ArticleYear
The thienopyridines.
    Journal of interventional cardiology, 2002, Volume: 15, Issue:1

    Topics: Clopidogrel; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine

2002
Platelets: is aspirin sufficient or must we know how to pronounce abciximab?
    Seminars in vascular surgery, 2002, Volume: 15, Issue:4

    Topics: Abciximab; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Blood Platelets; Clopidogrel; Endarterectomy, Carotid; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine; Tirofiban; Tyrosine

2002
Role of antiplatelet drugs in the prevention of cardiovascular events.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Aspirin; Benzamidines; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stroke; Ticlopidine; Treatment Outcome

2003
Clopidogrel's role in the management of atherosclerotic disease: a focus on acute coronary syndromes.
    Expert review of cardiovascular therapy, 2003, Volume: 1, Issue:4

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Stents; Ticlopidine; Treatment Outcome; Vascular Diseases

2003
Platelet ADP receptor antagonists: ticlopidine and clopidogrel.
    Best practice & research. Clinical haematology, 2004, Volume: 17, Issue:1

    Topics: Arteriosclerosis; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Ticlopidine; Treatment Outcome

2004
Acute coronary syndromes in women: is treatment different? Should it be?
    Current cardiology reports, 2004, Volume: 6, Issue:4

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Bypass; Female; Fibrinolytic Agents; Humans; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stents; Syndrome; Thrombin; Ticlopidine; Women's Health

2004
Antiplatelet agents.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5 Suppl 3

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Design; Drug Resistance; Drug Therapy, Combination; Humans; Meta-Analysis as Topic; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine

2004
Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
    Chest, 2004, Volume: 126, Issue:3 Suppl

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Contraindications; Coronary Restenosis; Coronary Stenosis; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Risk Assessment; Stents; Ticlopidine

2004
Optimal antithrombotic treatment for percutaneous coronary intervention.
    Minerva cardioangiologica, 2005, Volume: 53, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Coagulation; Clinical Trials as Topic; Clopidogrel; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stents; Thrombin; Thrombosis; Ticlopidine; Treatment Outcome

2005
The platelet P2 receptors in thrombosis.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:2

    Topics: Adenosine Diphosphate; Animals; Blood Vessels; Clinical Trials as Topic; Clopidogrel; Fibrinolytic Agents; Hemorrhagic Disorders; Humans; Membrane Proteins; Mice; Mice, Knockout; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Ticlopidine

2005
Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:2

    Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Cohort Studies; Double-Blind Method; Drug Resistance; Fibrinolytic Agents; Forecasting; Humans; Membrane Proteins; Meta-Analysis as Topic; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombophilia; Thrombosis; Ticlopidine

2005
Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:2

    Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Biotransformation; Clinical Trials, Phase I as Topic; Clopidogrel; Collagen; Drug Evaluation, Preclinical; Drug Synergism; Fibrinolytic Agents; Hemostasis; Humans; Male; Membrane Proteins; Molecular Structure; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Thrombin; Thrombosis; Ticlopidine

2005
Therapeutic approaches in arterial thrombosis.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Coronary Thrombosis; Disease Models, Animal; Disease Progression; Fibrinolytic Agents; Humans; Mice; Models, Biological; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Risk; Signal Transduction; Thrombosis; Ticlopidine; Time Factors

2005
Clinical applications of antiplatelet therapy.
    Reviews in cardiovascular medicine, 2006,Summer, Volume: 7, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine

2006
Prasugrel.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:12

    Topics: Adenosine Diphosphate; Animals; Aspirin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Clopidogrel; Collagen; Coronary Disease; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Drugs, Investigational; Humans; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2006
Thienopyridines in cardiovascular disease: focus on clopidogrel resistance.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:3

    Topics: Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Design; Drug Resistance; Drugs, Investigational; Humans; Membrane Proteins; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2007
Oral antiplatelet therapy for percutaneous coronary revascularization.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Apr-01, Volume: 69, Issue:5

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine

2007
ST-elevation myocardial infarction: the role of adjunctive antiplatelet therapy.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:2

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Clopidogrel; Electrocardiography; Eptifibatide; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine; Tirofiban; Tyrosine

2008
Review of the 2005 American College of Cardiology, American Heart Association, and Society for Cardiovascular Interventions guidelines for adjunctive pharmacologic therapy during percutaneous coronary interventions: practical implications, new clinical da
    American heart journal, 2008, Volume: 155, Issue:5

    Topics: American Heart Association; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug-Eluting Stents; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Societies, Medical; Thrombolytic Therapy; Ticlopidine; United States

2008
Antiplatelet drugs in cardiological practice: established strategies and new developments.
    Vascular health and risk management, 2008, Volume: 4, Issue:3

    Topics: Atherosclerosis; Clopidogrel; Drug-Eluting Stents; Humans; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Thromboxane; Signal Transduction; Thiophenes; Thrombosis; Ticlopidine

2008
Emergence of the concept of platelet reactivity monitoring of response to thienopyridines.
    Heart (British Cardiac Society), 2009, Volume: 95, Issue:15

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Thrombosis; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Antagonists; Pyridines; Ticlopidine

2009
Prasugrel: newest antiplatelet agent and its emerging role in management of acute coronary syndrome and percutaneous coronary intervention.
    Future cardiology, 2009, Volume: 5, Issue:3

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine

2009
A new generation of antiplatelet agents.
    Current opinion in cardiology, 2009, Volume: 24, Issue:4

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Ticlopidine; von Willebrand Factor

2009
P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use.
    European heart journal, 2009, Volume: 30, Issue:16

    Topics: Acute Coronary Syndrome; Clopidogrel; Cytochrome P-450 Enzyme System; Humans; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Thiophenes; Ticlopidine

2009
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.
    Lancet (London, England), 2009, Sep-19, Volume: 374, Issue:9694

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Proton Pump Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticlopidine; Treatment Outcome

2009
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part II. Clinical pharmacology of clopidogrel].
    Kardiologiia, 2009, Volume: 49, Issue:10

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Treatment Outcome

2009
Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:2

    Topics: Acute Coronary Syndrome; Aryl Hydrocarbon Hydroxylases; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine

2010
[Thienopyridines in the treatment and prevention of cardiovascular diseases. III. therapeutic application of clopidogrel as monotherapy (without acetylsalicylic acid)].
    Kardiologiia, 2009, Volume: 49, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Ticlopidine; Ulcer

2009
Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Benzofurans; Blood Platelets; Carbamates; Clinical Trials as Topic; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Receptor, PAR-1; Receptors, Proteinase-Activated; Thiophenes; Ticagrelor; Ticlopidine; von Willebrand Factor

2010
Combination antithrombotic therapies.
    Circulation, 2010, Feb-02, Volume: 121, Issue:4

    Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Pyridines; Thrombosis; Ticlopidine

2010
Preventing serious sequelae after an acute coronary syndrome: the consequences of thrombosis versus bleeding with antiplatelet therapy.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:6

    Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Thrombosis; Ticlopidine

2010
Antiplatelet therapy in percutaneous coronary intervention: recent advances in oral antiplatelet agents.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2010
Platelet P2Y₁₂ receptor inhibition: an update on clinical drug development.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:4

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2Y12; Ticlopidine

2010
Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery.
    The Annals of thoracic surgery, 2010, Volume: 90, Issue:3

    Topics: Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Thrombosis; Ticlopidine

2010
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part V. Combination of clopidogrel and acetylsalicylic acid in the treatment of stable patients with atherothrombotic cardiovascular diseases].
    Kardiologiia, 2010, Volume: 50, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Circulation; Death, Sudden, Cardiac; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Streptokinase; Stroke; Thrombosis; Ticlopidine; Time Factors

2010
[ST-elevation myocardial infarction: reperfusion strategy based on the results from large clinical trials].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:10 Suppl 1

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Fibrinolytic Agents; Guidelines as Topic; Heparin; Humans; Meta-Analysis as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Quality of Life; Randomized Controlled Trials as Topic; Thrombolytic Therapy; Ticlopidine; Time Factors

2010
[ADP receptor blockers: new insights in the therapy and prophylaxis of ischemic heart disease].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:27

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Stents; Ticlopidine

2011
Thienopyridine-associated drug-drug interactions: pharmacologic mechanisms and clinical relevance.
    Current cardiology reports, 2011, Volume: 13, Issue:5

    Topics: Clopidogrel; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Pyridines; Ticlopidine

2011
A meta-analysis of randomized controlled trials appraising the efficacy and safety of cilostazol after coronary artery stent implantation.
    Cardiology, 2012, Volume: 122, Issue:3

    Topics: Aspirin; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cilostazol; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Stents; Tetrazoles; Ticlopidine; Treatment Outcome

2012
Metabolic differences of current thienopyridine antiplatelet agents.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:3

    Topics: Acute Coronary Syndrome; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Fibrinolytic Agents; Hemorrhage; Humans; Inactivation, Metabolic; Pharmacogenetics; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Pyridines; Thiophenes; Ticlopidine

2013
New antiplatelet agents for cardiovascular disease.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Nov-05, Volume: 185, Issue:16

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2013

Trials

13 trial(s) available for clopidogrel and thienopyridine

ArticleYear
Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial.
    Circulation, 2005, Jun-28, Volume: 111, Issue:25

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemorrhage; Humans; Incidence; Male; Membrane Proteins; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2005
Aspirin, warfarin and a thienopyridine for acute coronary syndromes.
    Cardiology, 2006, Volume: 105, Issue:2

    Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Hematologic Agents; Humans; Male; Pyridines; Risk Factors; Syndrome; Ticlopidine; Ventricular Function; Warfarin

2006
Complementary effects of thienopyridine pretreatment and platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention; results from the ESPRIT trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Jul-01, Volume: 70, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Eptifibatide; Female; Hemorrhage; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Retrospective Studies; Risk Assessment; Stents; Ticlopidine; Time Factors; Treatment Outcome

2007
Efficacy and safety of triple antiplatelet therapy with and without concomitant anticoagulation during elective percutaneous coronary intervention (the REMOVE trial).
    The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Eptifibatide; Female; Heparin; Humans; Male; Middle Aged; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Pyridines; Ticlopidine; Treatment Outcome

2007
Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Adult; Aged; Clopidogrel; Comorbidity; Coronary Artery Disease; Diabetes Complications; Double-Blind Method; Drug Resistance; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prevalence; Pyridines; Thiophenes; Ticlopidine; Treatment Failure; Treatment Outcome

2008
Reducing cardiac ischemic events in patients with ACS: prasugrel versus clopidogrel. Commentary.
    Postgraduate medicine, 2010, Volume: 122, Issue:1

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Confidence Intervals; Double-Blind Method; Drug Therapy, Combination; Humans; Myocardial Ischemia; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine

2010
Bedside monitoring to adjust antiplatelet therapy for coronary stenting.
    The New England journal of medicine, 2012, Nov-29, Volume: 367, Issue:22

    Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Monitoring; Female; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Retreatment; Stents; Thiophenes; Ticlopidine

2012
Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:6

    Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Piperazines; Platelet Activation; Polymorphism, Genetic; Prasugrel Hydrochloride; Prospective Studies; Pyridines; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2013
Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial.
    European heart journal, 2014, Volume: 35, Issue:4

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Double-Blind Method; Embolism; Female; Humans; Kaplan-Meier Estimate; Male; Morpholines; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Rivaroxaban; Stroke; Thiophenes; Ticlopidine; Treatment Outcome; Warfarin

2014
Detecting a thienopyridine effect by platelet reactivity assessment and its implications for risk stratification.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:4

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome

2014
Thienopyridine reloading in clopidogrel-loaded patients undergoing percutaneous coronary interventions: The PRAISE study.
    International journal of cardiology, 2016, Nov-01, Volume: 222

    Topics: Aged; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Pyridines; Ticlopidine

2016
Optimal Same-Day Platelet Inhibition in Patients Receiving Drug-Eluting Stents With or Without Previous Maintenance Thienopyridine Therapy: from the Evaluation of Platelet Inhibition in Patients Having A VerifyNow Assay (EPIPHANY) Trial.
    The American journal of cardiology, 2017, Apr-01, Volume: 119, Issue:7

    Topics: Clopidogrel; Coronary Disease; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Pyridines; Risk Factors; Ticlopidine; Treatment Outcome

2017
Platelet reactivity and coronary microvascular impairment after percutaneous revascularization in stable patients receiving clopidogrel or prasugrel.
    Atherosclerosis, 2018, Volume: 278

    Topics: Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Double-Blind Method; Female; Humans; Male; Microcirculation; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Pyridines; Troponin T

2018

Other Studies

38 other study(ies) available for clopidogrel and thienopyridine

ArticleYear
Clopidogrel and percutaneous coronary intervention.
    Lancet (London, England), 2002, Jan-12, Volume: 359, Issue:9301

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Combined Modality Therapy; Coronary Disease; Double-Blind Method; Humans; Platelet Aggregation Inhibitors; Premedication; Pyridines; Research Design; Stents; Survival Analysis; Ticlopidine; Treatment Outcome

2002
[Premedication by thienopyridine before percutaneous coronary interventions in unstable angina].
    Annales de cardiologie et d'angeiologie, 2003, Volume: 52, Issue:3

    Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Clopidogrel; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Premedication; Pyridines; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2003
Paclitaxel-eluting coronary stents.
    The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Pyridines; Stents; Thrombosis; Ticlopidine

2004
Drug therapy during percutaneous coronary interventions in stable and unstable coronary artery disease: the Italian Drug Evaluation in Angioplasty (IDEA) study.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2005, Volume: 6, Issue:2

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Utilization Review; Female; Health Care Surveys; Heparin; Humans; Italy; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Registries; Ticlopidine

2005
Validation of predictors of intraprocedural stent thrombosis in the drug-eluting stent era.
    The American journal of cardiology, 2005, Jun-15, Volume: 95, Issue:12

    Topics: Acute Disease; Anticoagulants; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation; Clopidogrel; Coated Materials, Biocompatible; Coronary Angiography; Coronary Stenosis; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Female; Heparin; Humans; Intraoperative Complications; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Predictive Value of Tests; Pyridines; Retrospective Studies; Stents; Thrombolytic Therapy; Ticlopidine; Treatment Outcome

2005
Is platelet adhesion assay able to quantify drug-induced platelet dysfunction?
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:4

    Topics: Abciximab; Aged; Antibodies, Monoclonal; Blood Platelet Disorders; Blood Platelets; Cell Separation; Clopidogrel; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Flow Cytometry; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Polymers; Pyridines; Ticlopidine; Tirofiban; Tyrosine

2005
Drawbacks of nonrandomized trials in acute coronary syndromes.
    The American journal of cardiology, 2006, Jan-01, Volume: 97, Issue:1

    Topics: Angina, Unstable; Cardiac Catheterization; Clinical Trials as Topic; Clopidogrel; Coronary Angiography; Data Interpretation, Statistical; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stents; Syndrome; Ticlopidine; Time Factors

2006
Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry.
    Circulation, 2006, Jun-20, Volume: 113, Issue:24

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Cause of Death; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Drug Administration Schedule; Drug Implants; Female; Follow-Up Studies; Hospitalization; Humans; Life Tables; Male; Middle Aged; Mortality; Myocardial Infarction; Patient Education as Topic; Platelet Aggregation Inhibitors; Prevalence; Proportional Hazards Models; Prospective Studies; Pyridines; Registries; Sirolimus; Stents; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome; Treatment Refusal

2006
[Recurrent hemoptysis following thienopyridines and amiodarone administration. therapeutic dilemma].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:2

    Topics: Aged; Amiodarone; Cardiovascular Agents; Clopidogrel; Coronary Disease; Drug Interactions; Drug Therapy, Combination; Hemoptysis; Humans; Male; Platelet Aggregation Inhibitors; Pyridines; Recurrence; Ticlopidine

2005
Drug-eluting stents: dual antiplatelet therapy for every survivor?
    Circulation, 2007, Aug-14, Volume: 116, Issue:7

    Topics: Algorithms; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Incidence; Paclitaxel; Platelet Aggregation Inhibitors; Pyridines; Sirolimus; Stents; Survivors; Thrombosis; Ticlopidine

2007
Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR Project.
    Journal of the American College of Cardiology, 2007, Sep-18, Volume: 50, Issue:12

    Topics: Adverse Drug Reaction Reporting Systems; Age Distribution; Aged; Analysis of Variance; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Plasma Exchange; Platelet Aggregation Inhibitors; Probability; Purpura, Thrombotic Thrombocytopenic; Pyridines; Risk Assessment; Severity of Illness Index; Sex Distribution; Survival Analysis; Ticlopidine

2007
Platelet function testing and cardiovascular outcomes: steps forward in identifying the best predictive measure.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:4

    Topics: Adenosine Diphosphate; Cardiovascular Diseases; Clopidogrel; Flow Cytometry; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Pyridines; ROC Curve; Sensitivity and Specificity; Ticlopidine; Treatment Outcome

2007
The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents.
    Journal of the American College of Cardiology, 2008, Jun-10, Volume: 51, Issue:23

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Disease Progression; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Time Factors; Treatment Outcome

2008
The pursuit of clinically relevant measures of platelet function after antiplatelet drug therapy.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticlopidine; Treatment Failure

2008
Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine.
    Drug metabolism and pharmacokinetics, 2008, Volume: 23, Issue:6

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Oxidoreductases, N-Demethylating; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine

2008
Update on dual antiplatelet therapy for percutaneous coronary intervention.
    Heart (British Cardiac Society), 2009, Volume: 95, Issue:11

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pyridines; Stents; Thrombosis; Ticlopidine

2009
Future of oral antiplatelet therapy: four challenged hypotheses.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:6

    Topics: Adenosine; Clinical Trials as Topic; Clopidogrel; Coronary Thrombosis; Cost-Benefit Analysis; Hemorrhage; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Prognosis; Purinergic P2 Receptor Antagonists; Pyridines; Risk Assessment; Survival Rate; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2009
Drug-specific thienopyridine resistance in patient with recurrent coronary stent thrombosis.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Thrombosis; Drug Resistance; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Secondary Prevention; Stents; Ticlopidine

2009
Test before you stop.
    Archives of surgery (Chicago, Ill. : 1960), 2009, Volume: 144, Issue:8

    Topics: Adenosine; Algorithms; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Perioperative Care; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2009
Comparison of ticagrelor and thienopyridine P2Y(12) binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis.
    Thrombosis research, 2009, Volume: 124, Issue:5

    Topics: Adenosine; Animals; CHO Cells; Clopidogrel; Cricetinae; Cricetulus; Disease Models, Animal; Dogs; Hemostasis; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine; Transfection

2009
A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:11

    Topics: Clopidogrel; Cytochrome P-450 Enzyme System; Genetic Variation; Humans; Microsomes, Liver; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine

2009
Risk of combining PPIs with thienopyridines: fact or fiction?
    Lancet (London, England), 2009, Sep-19, Volume: 374, Issue:9694

    Topics: Biotransformation; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Pyridines; Thiophenes; Ticlopidine

2009
Antiplatelet therapy after coronary intervention in Asia and Japan: the Asian perspective of antiplatelet intervention.
    Hamostaseologie, 2009, Volume: 29, Issue:4

    Topics: Asia; Cerebral Hemorrhage; Cerebrovascular Disorders; Cilostazol; Clopidogrel; Coronary Disease; Europe; Humans; Liver; North America; Platelet Aggregation Inhibitors; Pyridines; Tetrazoles; Ticlopidine

2009
Clinical trial update II: TRITON-TIMI 38 provides reassurance on concomitant use of proton pump inhibitors and thienopyridines.
    European heart journal, 2009, Volume: 30, Issue:23

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Thiophenes; Ticlopidine

2009
Genotyping, clopidogrel metabolism, and the search for the therapeutic window of thienopyridines.
    Circulation, 2010, Feb-02, Volume: 121, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Gene Frequency; Genotype; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Pyridines; Ticlopidine

2010
Impact of high-responsiveness to dual antiplatelet therapy on bleeding complications in patients receiving drug-eluting stents.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:4

    Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyridines; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome

2010
Letter by Potter and Le Lorier regarding article, "Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome".
    Circulation, 2010, Aug-03, Volume: 122, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Clopidogrel; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Pyridines; Selection Bias; Ticlopidine

2010
[Does dual antiplatelet therapy always require gastroprotection? Tailored medical therapy should prevail over the generalized prescription of proton pump inhibitors in patients on dual antiplatelet therapy].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:6

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Myocardial Revascularization; Odds Ratio; Peptic Ulcer; Platelet Aggregation Inhibitors; Prognosis; Proton Pump Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Ticlopidine; Time Factors

2010
Combination of low-dose aspirin and thienopyridine exacerbates small bowel injury.
    Scandinavian journal of gastroenterology, 2011, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Capsule Endoscopy; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Pyridines; Retrospective Studies; Ticlopidine; Ulcer; Warfarin

2011
Duration of dual antiplatelet therapy and long-term clinical outcome after coronary drug-eluting stent implantation: landmark analyses from the CREDO-Kyoto PCI/CABG Registry Cohort-2.
    Circulation. Cardiovascular interventions, 2012, Volume: 5, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Pyridines; Registries; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2012
Reversal of thienopyridine-induced platelet dysfunction following desmopressin administration.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:2

    Topics: Animals; Antidiuretic Agents; Bleeding Time; Clopidogrel; Deamino Arginine Vasopressin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Hemostatics; Injections, Intravenous; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Purinergic P2Y Receptor Antagonists; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Ticlopidine

2013
Antiplatelet effect of thienopyridine (clopidogrel or prasugrel) pretreatment in patients undergoing primary percutaneous intervention for ST elevation myocardial infarction.
    The American journal of cardiology, 2013, Nov-15, Volume: 112, Issue:10

    Topics: Clopidogrel; Coronary Angiography; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Pyridines; Thiophenes; Ticlopidine; Treatment Outcome

2013
Transient receptor potential ankyrin 1 (TRPA1) channel activation by the thienopyridine-type drugs ticlopidine, clopidogrel, and prasugrel.
    Cell calcium, 2014, Volume: 55, Issue:4

    Topics: Calcium; Calcium Channels; Cell Line; Clopidogrel; Enterochromaffin-like Cells; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Nerve Tissue Proteins; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Serotonin; Thiophenes; Ticlopidine; Time-Lapse Imaging; Transient Receptor Potential Channels; TRPA1 Cation Channel

2014
The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention.
    American heart journal, 2014, Volume: 167, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Early Medical Intervention; Female; Guideline Adherence; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Patient Transfer; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Retrospective Studies; Ticlopidine; Time-to-Treatment

2014
A new mechanism of action of thienopyridine antiplatelet drugs - a role for gastric nitrosthiol metabolism?
    Atherosclerosis, 2014, Volume: 237, Issue:1

    Topics: Acute Coronary Syndrome; Blood Platelets; Clopidogrel; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Models, Biological; Nitrates; Nitric Oxide; Nitrogen; Oxygen; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2Y12; S-Nitrosothiols; Sulfhydryl Compounds; Ticlopidine

2014
Synthesis of the alkylated active metabolite of tipidogrel.
    Bioorganic & medicinal chemistry letters, 2015, Apr-15, Volume: 25, Issue:8

    Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; Clopidogrel; Half-Life; Piperidines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2Y12; Tandem Mass Spectrometry; Thiophenes; Ticlopidine

2015
Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease.
    The American journal of medicine, 2016, Volume: 129, Issue:6

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hospitalization; Humans; Male; Markov Chains; Monte Carlo Method; Myocardial Infarction; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Pyridines; Registries; Stroke; Ticlopidine; Warfarin

2016
Impact of preoperative dual antiplatelet therapy on bleeding complications in patients with acute coronary syndromes who undergo urgent coronary artery bypass grafting.
    Journal of cardiology, 2017, Volume: 69, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Emergencies; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Pyridines; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome

2017