clopidogrel and ritonavir

clopidogrel has been researched along with ritonavir in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's9 (90.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Metzger, NL; Momary, KM1
Arya, V; Mishra, P; Reynolds, KS; Younis, IR; Zhao, P1
Backman, JT; Itkonen, MK; Lapatto-Reiniluoto, O; Neuvonen, M; Neuvonen, PJ; Niemi, M; Tornio, A2
Shebley, M1

Reviews

3 review(s) available for clopidogrel and ritonavir

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors

2012
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for clopidogrel and ritonavir

ArticleYear
Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel.
    Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:1

    Topics: 2-Naphthylamine; Adult; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Ritonavir; Sulfonamides; Uracil; Young Adult

2019

Other Studies

6 other study(ies) available for clopidogrel and ritonavir

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
A patient with HIV and tuberculosis with diminished clopidogrel response.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:7

    Topics: Antitubercular Agents; Clopidogrel; Drug Interactions; Drug Resistance; HIV Infections; HIV Protease Inhibitors; Humans; Isoniazid; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Ritonavir; Ticlopidine; Tuberculosis

2014
Utilizing PBPK Modeling to Evaluate the Potential of a Significant Drug-Drug Interaction Between Clopidogrel and Dasabuvir: A Scientific Perspective.
    Clinical pharmacology and therapeutics, 2017, Volume: 102, Issue:4

    Topics: 2-Naphthylamine; Antiviral Agents; Clopidogrel; Cytochrome P-450 CYP2C8; Drug Combinations; Drug Interactions; Glucuronides; Humans; Macrocyclic Compounds; Models, Biological; Ritonavir; Sulfonamides; Ticlopidine; Uracil

2017
Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?
    Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:2

    Topics: 2-Naphthylamine; Clopidogrel; Ritonavir; Sulfonamides; Uracil

2019
Response to "Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?"
    Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:2

    Topics: 2-Naphthylamine; Clopidogrel; Ritonavir; Sulfonamides; Uracil

2019