clopidogrel and prasugrel

clopidogrel has been researched along with prasugrel in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H1
Gong, Y; Jiao, B; Lv, F; Qi, X; Shan, J; Sun, H; Yuan, F; Zhang, B; Zheng, W; Zhu, Y1
Chen, XQ; Crain, E; Hua, J; Huang, CS; Lai, A; Lam, PY; Price, LA; Qiao, JX; Rehfuss, R; Seiffert, DA; Shen, H; Wang, TC; Wang, Y; Watson, C; Wexler, RR; Wong, P; Yang, W1
Badorc, A; Barré, G; Besse, A; Boldron, C; Bonnet-Lignon, S; Bono, F; Bordes, MF; Briot, C; Delesque, N; Dol, F; Fossey, V; Gau, B; Hérault, JP; Herbert, JM; Lassalle, G; Meneyrol, J; Millet, L; Nazare, M; Pflieger, AM; Rousseaux, T; Savi, P; Tissandié, S; Yvon, X; Zech, G1
Chen, B; Danon, JJ; Kassiou, M; Ma, BB; Montgomery, AP1

Reviews

2 review(s) available for clopidogrel and prasugrel

ArticleYear
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors

2012
Strategies for targeting the P2Y
    Bioorganic & medicinal chemistry letters, 2022, 09-01, Volume: 71

    Topics: Central Nervous System; Ligands; Microglia; Platelet Aggregation; Receptors, Purinergic P2Y12; Signal Transduction

2022

Other Studies

3 other study(ies) available for clopidogrel and prasugrel

ArticleYear
Overcoming clopidogrel resistance: discovery of vicagrel as a highly potent and orally bioavailable antiplatelet agent.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Administration, Oral; Animals; Biological Availability; Clopidogrel; Drug Resistance; Female; In Vitro Techniques; Male; Mice; Microsomes, Liver; Phenylacetates; Platelet Aggregation Inhibitors; Prodrugs; Rats; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Ticlopidine

2012
Discovery of 4-aryl-7-hydroxyindoline-based P2Y1 antagonists as novel antiplatelet agents.
    Journal of medicinal chemistry, 2014, Jul-24, Volume: 57, Issue:14

    Topics: Animals; Blood Coagulation; Dose-Response Relationship, Drug; Drug Discovery; Humans; Indoles; Mice; Microsomes, Liver; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Rabbits; Rats; Receptors, Purinergic P2Y1; Structure-Activity Relationship; Thrombosis

2014
N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
    Journal of medicinal chemistry, 2014, Sep-11, Volume: 57, Issue:17

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Indoles; Injections, Intravenous; Male; Models, Chemical; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y12; Thrombosis

2014