clopidogrel and piperidines

clopidogrel has been researched along with piperidines in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bernat, A; Herbert, JM; Hoffmann, P; Savi, P1
Breddin, HK; Graff, J; Harder, S; Kirchmaier, CM; Klinkhardt, U; Mahnel, R; Westrup, D1
Davis, CJ; Lowry, DR; McKenzie, ME; Nair, GV; Serebruany, VL1
Sternon, J1
Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G1
Tendera, M; Wojakowski, W1
Schaerlig, E1
Aboul-Enein, HY; Nakashima, K; Nishiwaki, J; Ohwaki, Y; Wada, M; Yamane, T1
Kawashima, M; Murata, T; Terayama, Y1
Backman, JT; Filppula, AM; Kailari, O; Neuvonen, M; Neuvonen, PJ; Niemi, M; Nyrönen, TH; Tapaninen, T; Tornio, A1
Chen, L; Liu, D; Liu, Y; Tao, Z; Xia, G; Zhi, S1
Balasubramanian, B; Baran, PS; Bonacorsi, S; Cao, K; Chen, BC; Cortes, JC; Dai, J; Decicco, C; Goswami, A; Guo, Z; Hanson, R; Humphreys, WG; Lam, PY; Li, W; Mathur, A; Maxwell, BD; Michaudel, Q; Peng, L; Pudzianowski, A; Qiu, F; Shaw, SA; Su, S; Sun, D; Tymiak, AA; Vokits, BP; Wang, B; Wexler, R; Wu, DR; Zhang, Y; Zhao, R1
Aggarwal, H; Barthwal, MK; Bihan, D; Dhankani, P; Dikshit, DK; Dikshit, M; Farndale, RW; Kumar, S; Misra, A; Pandey, CP; Prakash, P; Pugh, N1
Lin, FJ; Lin, SY; Wang, CC; Wei, Y1
Cao, X; Gu, J; Li, X; Liu, P; Miao, Y; Sun, D; Xu, Z; Zhang, J1
Fujii, K; Hazama, Y; Kosugi, M; Miyoshi, Y; Nagata, S; Obata, Y; Takayama, K; Uehara, Y; Yamaguchi, H; Yasuda, T1

Reviews

3 review(s) available for clopidogrel and piperidines

ArticleYear
Aspirin in patients with coronary artery disease: is it simply irresistible?
    Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Benzamidines; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Diabetes Complications; Dipyridamole; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Endothelium, Vascular; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Oximes; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Thromboxane-A Synthase; Ticlopidine; Vasodilator Agents

2001
[New drugs].
    Revue medicale de Bruxelles, 2001, Volume: 22, Issue:4

    Topics: Amdinocillin; Carbamates; Clopidogrel; Cyclohexanes; Drug Interactions; Humans; Hypoglycemic Agents; Nateglinide; Patient Selection; Penicillins; Phenylalanine; Piperidines; Platelet Aggregation Inhibitors; Pneumococcal Vaccines; Raloxifene Hydrochloride; Safety; Selective Estrogen Receptor Modulators; Ticlopidine

2001
Role of antiplatelet drugs in the prevention of cardiovascular events.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Aspirin; Benzamidines; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stroke; Ticlopidine; Treatment Outcome

2003

Trials

1 trial(s) available for clopidogrel and piperidines

ArticleYear
Glucuronidation converts clopidogrel to a strong time-dependent inhibitor of CYP2C8: a phase II metabolite as a perpetrator of drug-drug interactions.
    Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Carbamates; Catalytic Domain; Clopidogrel; Computer Simulation; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Drug Interactions; Female; Glucuronides; Humans; Hypoglycemic Agents; Male; Metabolic Detoxication, Phase II; Molecular Docking Simulation; Piperidines; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2014

Other Studies

12 other study(ies) available for clopidogrel and piperidines

ArticleYear
Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:3

    Topics: Animals; Aspirin; Benzylamines; Clopidogrel; Hemodynamics; Hemostasis; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombosis; Ticlopidine

1997
Ex vivo--in vitro interaction between aspirin, clopidogrel, and the glycoprotein IIb/IIIa inhibitors abciximab and SR121566A.
    Clinical pharmacology and therapeutics, 2000, Volume: 67, Issue:3

    Topics: Abciximab; Administration, Oral; Adult; Analysis of Variance; Antibodies, Monoclonal; Aspirin; Benzylamines; Bleeding Time; Clopidogrel; Drug Administration Schedule; Drug Interactions; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Male; Nephelometry and Turbidimetry; P-Selectin; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Thiazoles; Ticlopidine

2000
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
    British journal of haematology, 2003, Volume: 120, Issue:4

    Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine

2003
[Highlights from the American College of Cardiology Annual Scientific Session 2005: March 5-9, 2005, Orlando, Florida].
    Revue medicale suisse, 2005, May-04, Volume: 1, Issue:18

    Topics: Aspirin; Cardiovascular Diseases; Cholesterol, LDL; Clopidogrel; Humans; Hypercholesterolemia; Obesity; Piperidines; Platelet Aggregation Inhibitors; Pyrazoles; Rimonabant; Stroke; Ticlopidine

2005
Interaction study of aspirin or clopidogrel on pharmacokinetics of donepezil hydrochloride in rats by HPLC-fluorescence detection.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:6

    Topics: Administration, Oral; Animals; Aspirin; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Clopidogrel; Donepezil; Drug Interactions; Fluorescence; Indans; Injections, Intraperitoneal; Male; Molecular Structure; Piperidines; Rats; Rats, Wistar; Ticlopidine

2007
[Case report: patient with central nervous system side effects due to lafutidine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012, Jul-10, Volume: 101, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetamides; Anti-Ulcer Agents; Central Nervous System Diseases; Clopidogrel; Histamine H2 Antagonists; Humans; Middle Aged; Piperidines; Pyridines; Rabeprazole; Stomach Ulcer; Ticlopidine

2012
Synthesis of the alkylated active metabolite of tipidogrel.
    Bioorganic & medicinal chemistry letters, 2015, Apr-15, Volume: 25, Issue:8

    Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; Clopidogrel; Half-Life; Piperidines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2Y12; Tandem Mass Spectrometry; Thiophenes; Ticlopidine

2015
Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development.
    The Journal of organic chemistry, 2015, Jul-17, Volume: 80, Issue:14

    Topics: Biological Phenomena; Clopidogrel; Humans; Microsomes, Liver; Piperidines; Platelet Aggregation Inhibitors; Prodrugs; Stereoisomerism; Ticlopidine

2015
Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.
    Biochemical pharmacology, 2018, Volume: 148

    Topics: Animals; Aspirin; Blood Coagulation; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thrombosis

2018
Risk of Hypoglycemia and Concomitant Use of Repaglinide and Clopidogrel: A Population-Based Nested Case-Control Study.
    Clinical pharmacology and therapeutics, 2019, Volume: 106, Issue:6

    Topics: Aged; Aspirin; Carbamates; Case-Control Studies; Clopidogrel; Drug Interactions; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Nateglinide; Piperidines; Platelet Aggregation Inhibitors

2019
A Pharmacodynamic Study of CN-218, a Novel Antiplatelet and Antithrombotic Agent Primarily Targeting the P2Y
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:1

    Topics: Animals; Blood Coagulation; Blood Platelets; Carrageenan; Clopidogrel; Cyclic AMP; Disease Models, Animal; Fibrinolytic Agents; Hemorrhage; Male; Mice; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Rats, Wistar; Receptors, Purinergic P2Y12; Thiophenes; Thrombosis

2020
Hypoglycemia during the Concomitant Use of Repaglinide and Clopidogrel in an Elderly Patient with Type 2 Diabetes and Severe Renal Insufficiency.
    Internal medicine (Tokyo, Japan), 2021, Volume: 60, Issue:6

    Topics: Aged; Blood Glucose; Carbamates; Clopidogrel; Diabetes Mellitus, Type 2; Humans; Hypoglycemia; Hypoglycemic Agents; Piperidines; Renal Insufficiency

2021