clopidogrel and hirudin

clopidogrel has been researched along with hirudin in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (4.94)18.2507
2000's41 (50.62)29.6817
2010's35 (43.21)24.3611
2020's1 (1.23)2.80

Authors

AuthorsStudies
Bernat, A; Herbert, JM; Maffrand, JP1
Beretz, A; Cazenave, JP; Freund, M; Gachet, C; Mantz, F; Meyer, L; Mulvihill, J; Nicolini, P1
Topol, EJ1
Boneu, B; Cazenave, JP; Freund, M; Léger, P; Magues, JP1
Bates, SM; Weitz, JI1
Maayani, S; Martinez, R; Schwarz, T; Tagliente, TM1
Moliterno, DJ; Saw, J1
Brener, SJ; Lincoff, AM; Moliterno, DJ; Steinhubl, SR; Topol, EJ; Wolski, KE1
Betriu, A; DeSmet, W; Kleiman, NS; Lincoff, AM; Rutsch, W; Saw, J; Topol, EJ; Wilcox, RG; Wolski, K1
Berger, P; Grines, C; Harrington, RA; Ohman, EM; Popma, JJ; Weitz, JI1
Aude, W; Garza, L; Husain, K; Matin, Z; Pacheco, R; Saucedo, JF; Thorn, B1
Benito, B; Betriu, A; Masotti, M1
Graff, J; Harder, S1
Bhatt, DL; Duffy, B1
Meyer Samama, M1
Krolick, MA1
Feit, F; Yehudai, L1
Spinler, SA1
Daemgen-von Brevern, G; Geisen, C; Klaeffling, C; Lindhoff-Last, E; Luxembourg, B; Mani, H; Strubel, G; Toennes, SW1
Anand, SX; Badimon, JJ; Carbon, F; Cavusoglu, E; Fareed, J; Hoppensteadt, DA; Kamran, M; Kim, MC; Kini, AS; Marmur, JD; Sharma, SK; Varon, D; Viles-Gonzalez, JF1
Horowitz, J; Kaski, JC; McMurray, JJ; Recio-Mayoral, A; Remme, WJ; van Veldhuisen, DJ1
Henry, I; Henry, M; Hugel, M; Polydorou, A1
Ortigosa, J1
Danchin, N; Decalf, V; Durand, E; Lafont, A; Sabbah, L1
Kwa, AT; Rogers, JH1
Iqbal, MB; Swanton, RH; Westwood, MA1
Brodie, BR1
Casterella, PJ; Tcheng, JE1
Braun, S; Busch, G; Jawansky, S; Kastrati, A; Ott, I; Schömig, A; Sibbing, D; von Beckerath, N1
Jennings, LK; Saucedo, JF1
Dovlatova, N; Heptinstall, S; Johnson, A1
Battistone, S; Coons, JC1
Schneider, DJ; Sobel, BE1
Berger, PB; Blankenship, JC; Büttner, HJ; Byrne, RA; Dirschinger, J; Graf, I; Iijima, R; Kastrati, A; Khattab, AA; Mehilli, J; Minners, J; Neumann, FJ; Pache, J; Richardt, G; Schömig, A; Schulz, S; Seyfarth, M; Skelding, KA1
Cohen, M; Giugliano, R; Granger, CB; Gurbel, PA; Hoekstra, J; Hollander, JE; Manoukian, SV; Pollack, CV; Saucedo, JF1
Antonino, MJ; Bassi, AK; Bliden, KP; DiChiara, J; Gesheff, TB; Gurbel, PA; Hennebry, TA; Herzog, WR; Mahla, E; Saucedo, JF; Singla, A; Suarez, TA; Tantry, US1
Bertrand, ME; Chew, D; Cox, DA; Desmet, W; Feit, F; Lincoff, AM; Manoukian, SV; Mehran, R; Ohman, EM; Pollack, CV; Steinhubl, SR; Stone, GW; Ware, JH1
Bergman, G; Feldman, DN; Minutello, RM; Wong, SC1
Gibson, CM; Hollander, JE; Pollack, CV1
Eberli, FR; Roffi, M1
Kereiakes, DJ1
Bett, N; Juneja, M; Ray, MJ; Walters, DL1
Bertrand, ME; Cox, DA; Dangas, GD; Fahy, M; Feit, F; Kirtane, AJ; Lansky, AJ; Lincoff, AM; Manoukian, SV; McLaurin, B; Mehran, R; Moses, JW; Nikolsky, E; Ohman, EM; Stone, GW; White, HD1
Aoki, J; Brodie, BR; Caixeta, A; Dangas, G; Dudek, D; Guagliumi, G; Kornowski, R; Mehran, R; Parise, H; Peruga, JZ; Rabbani, LE; Stone, GW; Witzenbichler, B1
Webster, MW1
Butwick, AJ; Carvalho, B1
Tricoci, P; Vergara-Jimenez, J1
Wessely, R1
Aïssaoui, N; Danchin, N1
Bergman, G; Feldman, DN; Minutello, RM; Moussa, I; Wong, SC1
Gilchrist, IC1
El-Atat, F; Jakkulla, M; Karajgikar, R; Kini, A; Kodali, V; Mares, A; Sarkar, K; Sharma, S1
Brodie, BR; Caixeta, A; Cristea, E; Dangas, GD; Dudek, D; Guagliumi, G; Lansky, AJ; Mehran, R; Möeckel, M; Parise, H; Peruga, JZ; Stone, GW; Witzenbichler, B1
Moliterno, DJ1
Amin, AP; Berger, P; Cohen, DJ; Kennedy, KF; Kleiman, N; Lopez, J; Pencina, M; Piana, RN1
Benenati, JF; Geisbüsch, P; Katzen, BT; Peña, C; Uthoff, H1
Basra, SS; Lakkis, NM; Tsai, P1
Elmariah, S; Jang, IK1
Ghosn, S; Sheikh-Taha, M1
Di Sciascio, G; Mangiacapra, F1
Bernlochner, I; Kastrati, A; Massberg, S; Mehilli, J; Schömig, A; Schulz, S; Sibbing, D1
Kim, MH; Yu, LH; Zhang, HZ1
Daly, RL; Dhutia, AJ; Ecob, R; Howgego, KE; Judge, HM; Mehra, S; Morton, AC; Storey, RF; Sumaya, W1
Bergmeijer, TO; Lichtveld, RA; Postma, S; Ten Berg, JM; Van't Hof, AW1
Bhatt, DL1
Acosta, J; Benezet, J; Cubero Gómez, JM; Díaz DE LA Llera, LS; Fernández-Cisnal, A; Parejo, J; Rangel, D; Zafra, F1
Gupta, K; Singh, D; Vacek, JL1
Brener, SJ; El-Omar, M; Gibson, CM; Maehara, A; Mehran, R; Oldroyd, KG; Stone, GW; Witzenbichler, B; Xu, K1
Braun, D; Gershlick, AH; Hauschke, D; Ibrahim, T; Kastrati, A; Laugwitz, KL; Mayer, K; Mehilli, J; Mehran, R; Morath, T; Neudecker, J; Richardt, G; Schulz, S; Schunkert, H; Tölg, R1
Byrne, RA; Kastrati, A; Laugwitz, KL; Ndrepepa, G; Neumann, FJ; Pache, J; Pöhler, A; Richardt, G; Schulz, S1
Abdel-Wahab, M; Anette Fiedler, K; Gershlick, AH; Hoppmann, P; Ibrahim, T; Kastrati, A; Kufner, S; Laugwitz, KL; Mehilli, J; Mehran, R; Morath, T; Neudecker, J; Richardt, G; Schneider, S; Schulz, S; Schunkert, H; Tölg, R1
Stone, GW1
Alexander, KP; Li, S; Magid, DJ; Peterson, ED; Roe, MT; Ting, HH; Wang, TY1
Baber, U; Badimon, JJ; Crippa, M; Giannarelli, C; Mehran, R; Rodriguez, D; Sartori, S; Tewar, MP; Vorchheimer, DA; Zafar, MU1
Clemmensen, P; Danchin, N; Goedicke, J; Goldstein, P; Grieco, N; Ince, H; Ramos, Y; Schmitt, J1
Bhatt, DL; Cortese, B; Deliargyris, EN; Gibson, CM; Hamm, CW; Harrington, RA; Liu, T; Mahaffey, KW; Prats, J; Price, MJ; Steg, PG; Stone, GW; White, HD; Wilensky, M1
Généreux, P; Kirtane, AJ; Madhavan, MV; Mehran, R; Stone, GW; Witzenbichler, B; Xu, K1
Braun, D; Braun, S; Hausleiter, J; Kastrati, A; Knipper, A; Massberg, S; Mehilli, J; Orban, M; Petzold, T; Schulz, S; Sibbing, D1
Baber, U; Berger, PB; Currier, J; Dave, RH; Henry, TD; Mehran, R; Nayyar, P; Rafique, AM; Tobis, J; Wang, TY1
Fichter, AM; Mitchell, DA; Mücke, T; Ritschl, LM; Robitzky, LK; Wagenpfeil, S; Wolff, KD1
Álvarez-Antón, S; Carballeira, D; Concepción, R; Dejuán-Bitriá, C; Del Castillo, H; Delgado-Calva, FA; López-Soberón, E; Marschall, A; Martí, D; Morales, MJ; Palazuelos, J; Pérez-Guzmán, J1

Reviews

26 review(s) available for clopidogrel and hirudin

ArticleYear
Evolution of improved antithrombotic and antiplatelet agents: genesis of the Comparison of Abciximab Complications with Hirulog [and back-Up Abciximab] Events Trial (CACHET).
    The American journal of cardiology, 1998, Oct-22, Volume: 82, Issue:8B

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Research Design; Ticlopidine

1998
Beyond heparin and aspirin: new treatments for unstable angina and non-Q-wave myocardial infarction.
    Archives of internal medicine, 2000, Mar-27, Volume: 160, Issue:6

    Topics: Angina, Unstable; Antithrombins; Clopidogrel; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thromboxane; Recombinant Proteins; Thromboxane-A Synthase; Ticlopidine

2000
Contemporary use of antiplatelet therapies in percutaneous coronary interventions.
    Coronary artery disease, 2003, Volume: 14, Issue:5

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Stents; Ticlopidine

2003
Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention.
    Circulation, 2004, Aug-24, Volume: 110, Issue:8

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Comorbidity; Coronary Restenosis; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Incidence; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Peptide Fragments; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recombinant Proteins; Retrospective Studies; Stents; Thrombophilia; Ticlopidine; Tirofiban; Tyrosine

2004
Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
    Chest, 2004, Volume: 126, Issue:3 Suppl

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Contraindications; Coronary Restenosis; Coronary Stenosis; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Risk Assessment; Stents; Ticlopidine

2004
[Advances in adjunctive pharmacological therapy for percutaneous coronary interventions].
    Revista espanola de cardiologia, 2005, Volume: 58, Issue:6

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Cardiac Catheterization; Clopidogrel; Coronary Restenosis; Factor X; Fibrinolytic Agents; Follow-Up Studies; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Immunosuppressive Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Risk Factors; Sirolimus; Stents; Thrombolytic Therapy; Thrombosis; Ticlopidine; Time Factors

2005
Antiplatelet agents in patients undergoing percutaneous coronary intervention: how many and how much?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005, Volume: 5, Issue:5

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clinical Trials as Topic; Clopidogrel; Eptifibatide; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Recombinant Proteins; Ticlopidine; Tirofiban; Tyrosine

2005
[The new antithrombotic agents].
    Presse medicale (Paris, France : 1983), 2005, Oct-22, Volume: 34, Issue:18

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Azetidines; Benzylamines; Clopidogrel; Fibrinolytic Agents; Glycine; Hirudins; Humans; Injections, Subcutaneous; Platelet Aggregation Inhibitors; Polysaccharides; Prodrugs; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine; Time Factors; Venous Thrombosis

2005
Debate of adjunctive pharmacology for percutaneous coronary intervention: thrombin inhibitors and clopidogrel are enough.
    Journal of interventional cardiology, 2006, Volume: 19, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Clopidogrel; Combined Modality Therapy; Coronary Disease; Heparin; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Recombinant Proteins; Ticlopidine

2006
[Optimizing antithrombotic therapy in non-ST-elevation acute coronary syndrome].
    Revista espanola de cardiologia, 2007, Volume: 60 Suppl 3

    Topics: Acute Coronary Syndrome; Anticoagulants; Clopidogrel; Fibrinolytic Agents; Fondaparinux; Hirudins; Humans; Peptide Fragments; Polysaccharides; Recombinant Proteins; Ticlopidine

2007
[Gp IIb/IIIa receptor antagonists in acute coronary syndromes with no ST elevation].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:12

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Hirudins; Humans; Myocardial Infarction; Myocardial Revascularization; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Recombinant Proteins; Ticlopidine; Troponin T

2007
Current update on glycoprotein IIb-IIIa and direct thrombin inhibition in percutaneous coronary intervention for non-ST elevation acute coronary syndromes: balancing bleeding risk and antiplatelet efficacy.
    Journal of interventional cardiology, 2008, Volume: 21, Issue:2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Enoxaparin; Eptifibatide; Fibrinolytic Agents; Heart Conduction System; Hemorrhage; Heparin; Hirudins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Risk Factors; Ticlopidine

2008
Recent developments in acute coronary syndromes.
    Clinical medicine (London, England), 2008, Volume: 8, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antithrombins; Clopidogrel; Fondaparinux; Heparin, Low-Molecular-Weight; Hirudins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Recombinant Proteins; Thrombolytic Therapy; Ticlopidine

2008
Review of the 2005 American College of Cardiology, American Heart Association, and Society for Cardiovascular Interventions guidelines for adjunctive pharmacologic therapy during percutaneous coronary interventions: practical implications, new clinical da
    American heart journal, 2008, Volume: 155, Issue:5

    Topics: American Heart Association; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug-Eluting Stents; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Societies, Medical; Thrombolytic Therapy; Ticlopidine; United States

2008
Antiplatelet and anticoagulant agents: key differences in mechanisms of action, clinical application, and therapeutic benefit in patients with non-ST-segment-elevation acute coronary syndromes.
    Current opinion in cardiology, 2008, Volume: 23, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine

2008
Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.
    Journal of interventional cardiology, 2008, Volume: 21, Issue:4

    Topics: Acute Coronary Syndrome; Algorithms; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Agents; Clinical Trials as Topic; Clopidogrel; Emergency Treatment; Evidence-Based Medicine; Fibrinolytic Agents; Hirudins; Humans; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Hemorrhage; Practice Guidelines as Topic; Prasugrel Hydrochloride; Recombinant Proteins; Risk Assessment; Stents; Thiophenes; Thrombosis; Ticlopidine

2008
Hospitals with and without percutaneous coronary intervention capability: considerations for treating acute coronary syndromes.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Emergency Service, Hospital; Enoxaparin; Fondaparinux; Health Services Accessibility; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Polysaccharides; Recombinant Proteins; Ticlopidine; Triage; United States

2009
Diabetes and acute coronary syndromes.
    Best practice & research. Clinical endocrinology & metabolism, 2009, Volume: 23, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enoxaparin; Hirudins; Humans; Hypoglycemic Agents; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Recombinant Proteins; Thiophenes; Thrombosis; Ticlopidine

2009
Improving adjunctive pharmacotherapy for primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: beyond the HORIZONS-AMI trial.
    Reviews in cardiovascular medicine, 2009,Spring, Volume: 10, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Chemotherapy, Adjuvant; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Heparin; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Recombinant Proteins; Risk Assessment; Thiophenes; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2009
Neuraxial anesthesia in obstetric patients receiving anticoagulant and antithrombotic drugs.
    International journal of obstetric anesthesia, 2010, Volume: 19, Issue:2

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Anticoagulants; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Fondaparinux; Guidelines as Topic; Hematoma, Epidural, Spinal; Heparin; Hirudins; Humans; Polysaccharides; Pregnancy; Ticlopidine; Warfarin

2010
Safety and efficacy of abciximab as an adjunct to percutaneous coronary intervention.
    Vascular health and risk management, 2010, Mar-03, Volume: 6

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Coronary Artery Disease; Electrocardiography; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Recombinant Proteins; Ticlopidine

2010
Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Disease Management; Drug Synergism; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Recombinant Proteins; Thiophenes; Ticagrelor; Ticlopidine

2010
Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
    Journal of the American College of Cardiology, 2011, Nov-22, Volume: 58, Issue:22

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; Kidney Diseases; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Recombinant Proteins; Thiophenes; Ticagrelor; Ticlopidine; Uremia

2011
Prehospital treatment of ST-segment elevated myocardial infarction patients.
    Future cardiology, 2013, Volume: 9, Issue:2

    Topics: Antithrombins; Clopidogrel; Electrocardiography; Emergency Medical Services; Hirudins; Humans; Myocardial Infarction; Myocardial Reperfusion; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recombinant Proteins; Registries; Survival Analysis; Thrombolytic Therapy; Ticlopidine; Time Factors; Treatment Outcome

2013
Anticoagulation and antiplatelet therapy in acute coronary syndromes.
    Cleveland Clinic journal of medicine, 2014, Volume: 81, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Enoxaparin; Fondaparinux; Heparin; Hirudins; Humans; Morpholines; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Thiophenes; Ticagrelor; Ticlopidine; Warfarin

2014
Optimal P2Y12 Inhibitor in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Network Meta-Analysis.
    JACC. Cardiovascular interventions, 2016, 05-23, Volume: 9, Issue:10

    Topics: Adenosine; Antithrombins; Bayes Theorem; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Evidence-Based Medicine; Hirudins; Humans; Markov Chains; Monte Carlo Method; Network Meta-Analysis; Odds Ratio; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Recombinant Proteins; Risk Factors; ST Elevation Myocardial Infarction; Ticagrelor; Ticlopidine; Treatment Outcome

2016

Trials

21 trial(s) available for clopidogrel and hirudin

ArticleYear
Lack of clopidogrel pretreatment effect on the relative efficacy of bivalirudin with provisional glycoprotein IIb/IIIa blockade compared to heparin with routine glycoprotein IIb/IIIa blockade: a REPLACE-2 substudy.
    Journal of the American College of Cardiology, 2004, Sep-15, Volume: 44, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Clopidogrel; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Survival Analysis; Ticlopidine; Treatment Outcome

2004
Inhibition of platelet aggregation with eptifibatide, bivalirudin, and heparin in patients undergoing percutaneous coronary intervention receiving clopidogrel pretreatment (The PharmacoDynamic Evaluation of Angiomax, Clopidogrel with or without INtegrilin
    The American journal of cardiology, 2005, Jun-15, Volume: 95, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Drug Therapy, Combination; Eptifibatide; Female; Follow-Up Studies; Heparin; Hirudins; Humans; Male; Middle Aged; Myocardial Ischemia; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Preoperative Care; Recombinant Proteins; Ticlopidine; Treatment Outcome

2005
Impact of bivalirudin or unfractionated heparin on platelet aggregation in patients pretreated with 600 mg clopidogrel undergoing elective percutaneous coronary intervention.
    European heart journal, 2008, Volume: 29, Issue:12

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Double-Blind Method; Female; Heparin; Hirudins; Humans; Male; Peptide Fragments; Perioperative Care; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Premedication; Recombinant Proteins; Ticlopidine

2008
Bivalirudin versus unfractionated heparin during percutaneous coronary intervention.
    The New England journal of medicine, 2008, Aug-14, Volume: 359, Issue:7

    Topics: Aged; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Double-Blind Method; Female; Hemorrhage; Heparin; Hirudins; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Premedication; Recombinant Proteins; Recurrence; Risk; Stents; Thrombosis; Ticlopidine

2008
Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to
    Journal of the American College of Cardiology, 2009, Feb-24, Volume: 53, Issue:8

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Blood Coagulation; Blood Platelets; Clopidogrel; Collagen; Drug Therapy, Combination; Eptifibatide; Female; Hemorheology; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Recombinant Proteins; Stents; Thrombelastography; Ticlopidine

2009
Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention: an analysis of the ACUITY (Acute Catheterization and U
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Troponin; Young Adult

2008
A comparison of anticoagulation with bivalirudin and provisional GPIIb/IIIa inhibition with unfractionated heparin and mandatory GPIIb/IIIa inhibition during percutaneous coronary intervention in relation to platelet activation and the inhibition of coagu
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 5, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Biomarkers; Blood Coagulation; CD40 Ligand; Clopidogrel; Drug Therapy, Combination; Female; Fibrinogen; Heparin; Hirudins; Humans; Lipoproteins; Male; Membrane Glycoproteins; Middle Aged; Monocytes; Peptide Fragments; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prothrombin; Recombinant Proteins; Thromboplastin; Thrombosis; Ticlopidine; Treatment Outcome

2009
Gastrointestinal bleeding in patients with acute coronary syndromes: incidence, predictors, and clinical implications: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.
    Journal of the American College of Cardiology, 2009, Sep-29, Volume: 54, Issue:14

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Coronary Artery Bypass; Female; Gastrointestinal Hemorrhage; Heparin; Hirudins; Humans; Incidence; Ischemia; Length of Stay; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Sex Factors; Stents; Thrombosis; Ticlopidine

2009
Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty: results from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial.
    Journal of the American College of Cardiology, 2009, Oct-06, Volume: 54, Issue:15

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon; Anticoagulants; Clopidogrel; Confidence Intervals; Female; Hirudins; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recombinant Proteins; Ticlopidine; Treatment Outcome

2009
A randomized pilot trial for aggressive therapeutic approaches in aspirin-resistant patients undergoing percutaneous coronary intervention.
    The Journal of invasive cardiology, 2011, Volume: 23, Issue:1

    Topics: Adult; Angioplasty, Balloon, Coronary; Antithrombins; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine

2011
Frequency and predictors of stent thrombosis after percutaneous coronary intervention in acute myocardial infarction.
    Circulation, 2011, Apr-26, Volume: 123, Issue:16

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Heparin; Hirudins; Humans; Male; Metals; Middle Aged; Myocardial Infarction; Paclitaxel; Peptide Fragments; Platelet Aggregation Inhibitors; Predictive Value of Tests; Recombinant Proteins; Risk Factors; Ticlopidine; Treatment Outcome; Tubulin Modulators

2011
A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: the tirofiban evaluation of novel dosing versus abciximab wi
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011, Jun-01, Volume: 77, Issue:7

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine; United States

2011
Prognostic value of a high on-clopidogrel treatment platelet reactivity in bivalirudin versus abciximab treated non-ST-segment elevation myocardial infarction patients. ISAR-REACT 4 (Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action fo
    Journal of the American College of Cardiology, 2012, Jul-31, Volume: 60, Issue:5

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Clopidogrel; Cohort Studies; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Recombinant Proteins; Signal Processing, Computer-Assisted; Stents; Survival Analysis; Ticlopidine

2012
Outcomes in patients with ST-segment elevation acute myocardial infarction treated with clopidogrel versus prasugrel (from the INFUSE-AMI trial).
    The American journal of cardiology, 2014, May-01, Volume: 113, Issue:9

    Topics: Antithrombins; Clopidogrel; Coronary Angiography; Electrocardiography; Female; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Recombinant Proteins; Thiophenes; Ticlopidine; Treatment Outcome

2014
Comparison of prasugrel and bivalirudin vs clopidogrel and heparin in patients with ST-segment elevation myocardial infarction: Design and rationale of the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 trial.
    Clinical cardiology, 2014, Volume: 37, Issue:5

    Topics: Anticoagulants; Clopidogrel; Drug Therapy, Combination; Female; Heparin; Hirudins; Humans; Male; Myocardial Infarction; Peptide Fragments; Percutaneous Coronary Intervention; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Recombinant Proteins; Thiophenes; Ticlopidine; Treatment Outcome

2014
Prasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction.
    European heart journal, 2014, Sep-07, Volume: 35, Issue:34

    Topics: Aged; Anticoagulants; Clopidogrel; Coronary Angiography; Coronary Stenosis; Drug Therapy, Combination; Early Termination of Clinical Trials; Heparin; Hirudins; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recombinant Proteins; Thiophenes; Ticlopidine; Treatment Outcome

2014
Ticagrelor reduces thrombus formation more than clopidogrel, even when co-administered with bivalirudin.
    Thrombosis and haemostasis, 2014, Volume: 112, Issue:5

    Topics: Adenosine; Adult; Antithrombins; Aspirin; Blood Coagulation; Clopidogrel; Cross-Over Studies; Drug Synergism; Female; Healthy Volunteers; Hirudins; Humans; Male; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Recombinant Proteins; Thrombelastography; Ticagrelor; Ticlopidine

2014
MULTInational non-interventional study of patients with ST-segment elevation myocardial infarction treated with PRimary Angioplasty and Concomitant use of upstream antiplatelet therapy with prasugrel or clopidogrel--the European MULTIPRAC Registry.
    European heart journal. Acute cardiovascular care, 2015, Volume: 4, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Antithrombins; Clopidogrel; Drug Therapy, Combination; Europe; Female; Hemorrhage; Hirudins; Humans; Internationality; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Recombinant Proteins; Ticlopidine; Treatment Outcome

2015
Outcomes with cangrelor versus clopidogrel on a background of bivalirudin: insights from the CHAMPION PHOENIX (A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention [PCI]).
    JACC. Cardiovascular interventions, 2015, Volume: 8, Issue:3

    Topics: Adenosine Monophosphate; Aged; Anticoagulants; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Female; Hemorrhage; Hirudins; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recombinant Proteins; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2015
Is routine post-procedural anticoagulation warranted after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction? Insights from the HORIZONS-AMI trial.
    European heart journal. Acute cardiovascular care, 2017, Volume: 6, Issue:7

    Topics: Aged; Antithrombins; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Care; Postoperative Complications; Prospective Studies; Recombinant Proteins; Secondary Prevention; ST Elevation Myocardial Infarction; Survival Rate; Thrombolytic Therapy; Ticlopidine; Treatment Outcome

2017
Platelet function and coagulation in patients with STEMI and peri-interventional clopidogrel plus heparin vs. prasugrel plus bivalirudin therapy (BRAVE 4 substudy).
    Thrombosis research, 2016, Volume: 137

    Topics: Antithrombins; Clopidogrel; Drug Therapy, Combination; Female; Heparin; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Thrombelastography; Ticlopidine; Treatment Outcome

2016

Other Studies

34 other study(ies) available for clopidogrel and hirudin

ArticleYear
Importance of platelets in experimental venous thrombosis in the rat.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Animals; Blood Platelets; Clopidogrel; Disease Models, Animal; Heparin; Hirudins; Leukopenia; Male; Mechlorethamine; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Thrombophlebitis; Thromboplastin; Ticlopidine

1992
Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition.
    Thrombosis and haemostasis, 1993, May-03, Volume: 69, Issue:5

    Topics: Animals; Anticoagulants; Arterio-Arterial Fistula; Aspirin; Carotid Artery Thrombosis; Clopidogrel; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrin; Fibrinogen; Fibrinolytic Agents; Glass; Heparin; Hirudin Therapy; Hirudins; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Polyethylenes; Rats; Rats, Wistar; Recombinant Proteins; Regional Blood Flow; Silicones; Thrombin; Ticlopidine

1993
Comparison of the antithrombotic effects of heparin, hirudin and clopidogrel according to the nature of the thrombogenic surface in an arterioarterial shunt in rats.
    Thrombosis and haemostasis, 1999, Volume: 82, Issue:3

    Topics: Animals; Clopidogrel; Disease Models, Animal; Female; Fibrinolytic Agents; Heparin; Hirudins; Rats; Rats, Wistar; Thrombosis; Ticlopidine

1999
Activation of Gi-coupled receptors releases a tonic state of inhibited platelet aggregation.
    Platelets, 2001, Volume: 12, Issue:2

    Topics: Adaptation, Physiological; Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Clopidogrel; Epinephrine; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Hirudins; Humans; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Receptor Agonists; Ticlopidine

2001
Investigation of the PADA as a method for monitoring GPIIb/IIIa inhibitors and other antiplatelet agents.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:4

    Topics: Abciximab; Adenosine Monophosphate; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Eptifibatide; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Sensitivity and Specificity; Ticlopidine

2005
Successful percutaneous coronary intervention using bivalirudin in a patient with chronic lymphocytic leukemia and thrombocytopenia.
    European journal of haematology, 2006, Volume: 77, Issue:4

    Topics: Aged; Cardiac Catheterization; Clopidogrel; Hirudins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Peptide Fragments; Recombinant Proteins; Thrombocytopenia; Ticlopidine

2006
Managing acute coronary syndrome: evidence-based approaches.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Jun-01, Volume: 64, Issue:11 Suppl 7

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Clinical Protocols; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Outcome Assessment, Health Care; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Recombinant Proteins; Ticlopidine

2007
Factitious anticoagulant-resistance as a cause of recurrent arterial bypass graft occlusions.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:6

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Factitious Disorders; Female; Graft Occlusion, Vascular; Heparin, Low-Molecular-Weight; Hirudins; Humans; Iliac Artery; Middle Aged; Munchausen Syndrome; Phenprocoumon; Platelet Aggregation Inhibitors; Recombinant Proteins; Recurrence; Reoperation; Ticlopidine; Treatment Refusal; Vascular Surgical Procedures

2007
Comparison of platelet function and morphology in patients undergoing percutaneous coronary intervention receiving bivalirudin versus unfractionated heparin versus clopidogrel pretreatment and bivalirudin.
    The American journal of cardiology, 2007, Aug-01, Volume: 100, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Blood Platelets; CD40 Ligand; Clopidogrel; Coronary Angiography; Dose-Response Relationship, Drug; Female; Heparin; Hirudins; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Peptide Fragments; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Ticlopidine

2007
Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:6

    Topics: Abciximab; Acute Coronary Syndrome; Amides; Antibodies, Monoclonal; Benzazepines; Clinical Trials as Topic; Clopidogrel; Electrocardiography; Europe; Fumarates; Heart Diseases; Heart Failure; Hirudins; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptide Fragments; Probucol; Recombinant Proteins; Ticlopidine; Tolvaptan

2007
Endovascular treatment of a renal artery stenosis: techniques, indications, results. Role of embolic protection devices (part 2).
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2007, Volume: 13, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catheterization; Clopidogrel; Embolism; Fibrinolytic Agents; Heparin; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Recombinant Proteins; Renal Artery Obstruction; Ticlopidine

2007
What anti-thrombotic therapy is best with primary PCI for acute ST elevation myocardial infarction: how should the HORIZONS trial change current practice?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, May-01, Volume: 71, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Myocardial Infarction; Patient Selection; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Recombinant Proteins; Research Design; Stents; Thrombin; Thrombosis; Ticlopidine; Treatment Outcome

2008
Multiple electrode aggregometry and P2Y(12) antagonists.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Anticoagulants; Clopidogrel; Dose-Response Relationship, Drug; Electrodes; Equipment Design; Hirudins; Humans; Peptide Fragments; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2008
2007 Guideline update for unstable angina/non-ST-segment elevation myocardial infarction: focus on antiplatelet and anticoagulant therapies.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:7

    Topics: American Heart Association; Angina, Unstable; Anticoagulants; Clopidogrel; Drug-Eluting Stents; Enoxaparin; Fondaparinux; Heparin; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Practice Guidelines as Topic; Recombinant Proteins; Ticlopidine; United States

2008
Lack of early augmentation of platelet reactivity after coronary intervention in patients treated with bivalirudin.
    Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:1

    Topics: Adenosine Diphosphate; Angina Pectoris; Anticoagulants; Aspirin; Cardiac Catheterization; Clopidogrel; Elective Surgical Procedures; Hemostatics; Hirudins; Humans; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Period; Recombinant Proteins; Thrombin; Ticlopidine; Time Factors

2009
Frequency and outcomes of provisional glycoprotein IIb/IIIa blockade in patients receiving bivalirudin during percutaneous coronary intervention.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:6

    Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Embolism; Eptifibatide; Female; Follow-Up Studies; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Registries; Regression Analysis; Retrospective Studies; Thrombosis; Ticlopidine; Treatment Outcome

2009
HORIZONS-AMI.
    Lancet (London, England), 2010, Jan-30, Volume: 375, Issue:9712

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Heparin; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Stents; Ticlopidine; Treatment Outcome

2010
Initial experience with an institutional bridging protocol for patients with recent coronary stent implantation requiring discontinuation of dual antiplatelet therapy resulting from urgent surgery.
    American journal of therapeutics, 2011, Volume: 18, Issue:6

    Topics: Antithrombins; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Recombinant Proteins; Stents; Surgical Procedures, Operative; Ticlopidine; Time Factors

2011
Efficacy and safety of bivalirudin in patients receiving clopidogrel therapy after diagnostic angiography for percutaneous coronary intervention in acute coronary syndromes.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, Oct-01, Volume: 76, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antithrombins; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Diseases; Hemorrhage; Heparin; Hirudins; Hospital Mortality; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; New York City; Odds Ratio; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Propensity Score; Proportional Hazards Models; Recombinant Proteins; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2010
It is standard practice, but is it really best practice or clinical biocreep?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, Oct-01, Volume: 76, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antithrombins; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Drug Therapy, Combination; Heart Diseases; Hemorrhage; Heparin; Hirudins; Hospital Mortality; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2010
Effect of clopidogrel pretreatment on ischemic complications of percutaneous coronary intervention among bivalirudin-treated patients (from the EVENT registry).
    The American journal of cardiology, 2011, Jun-15, Volume: 107, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Antithrombins; Clopidogrel; Female; Hemorrhage; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Premedication; Recombinant Proteins; Thrombosis; Ticlopidine

2011
Bivalirudin used as alternative anticoagulant in carotid artery stenting: a single center observational study.
    Journal of interventional cardiology, 2012, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antithrombins; Carotid Stenosis; Clopidogrel; Female; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation Inhibitors; Recombinant Proteins; Ticlopidine

2012
Acute stent thrombosis: technical complication or inadequate antithrombotic therapy? An optical coherence tomography study.
    JACC. Cardiovascular interventions, 2012, Volume: 5, Issue:2

    Topics: Acute Disease; Aged; Antithrombins; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Eptifibatide; Female; Fibrinolytic Agents; Heparin; Hirudins; Humans; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Recombinant Proteins; Risk Factors; Ticlopidine; Tomography, Optical Coherence

2012
Comparison of bolus only with bolus plus infusion of bivalirudin in patients undergoing elective percutaneous coronary intervention: a retrospective observational study.
    Journal of pharmacy practice, 2012, Volume: 25, Issue:5

    Topics: Aged; Alabama; Antithrombins; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Elective Surgical Procedures; Female; Hemorrhage; Hirudins; Humans; Incidence; Infusions, Intravenous; Injections, Intravenous; Ischemia; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recombinant Proteins; Retrospective Studies; Severity of Illness Index; Thrombosis; Ticlopidine

2012
Platelet reactivity and percutaneous coronary intervention: another clue in the quest for the Holy Grail of tailored antithrombotic therapy?
    Journal of the American College of Cardiology, 2012, Jul-31, Volume: 60, Issue:5

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Clopidogrel; Female; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Myocardial Infarction; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Stents; Ticlopidine

2012
Effect of different anticoagulants on multiple electrode platelet aggregometry after clopidogrel and aspirin administration in patients undergoing coronary stent implantation: a comparison between citrate and hirudin.
    Platelets, 2013, Volume: 24, Issue:5

    Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Arachidonic Acid; Aspirin; Citric Acid; Clopidogrel; Female; Hirudins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Ticlopidine

2013
Hirudin anticoagulation allows more rapid determination of P2Y₁₂ inhibition by the VerifyNow P2Y12 assay.
    Thrombosis and haemostasis, 2013, Volume: 109, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Antithrombins; Area Under Curve; Cations; Citrates; Clopidogrel; Coronary Angiography; Female; Hematologic Tests; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Function Tests; Prasugrel Hydrochloride; Receptors, Purinergic P2Y12; Sodium Citrate; Thiophenes; Ticlopidine; Treatment Outcome

2013
Bleeding complications during percutaneous coronary intervention.
    The Journal of invasive cardiology, 2004, Volume: 16, Issue:7 Suppl

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine

2004
A comparative study of bivalirudin plus clopidogrel versus bivalirudin plus prasugrel in primary angioplasty using propensity score matching.
    Journal of interventional cardiology, 2013, Volume: 26, Issue:5

    Topics: Angioplasty; Antithrombins; Clopidogrel; Cohort Studies; Drug Combinations; Female; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Piperazines; Postoperative Complications; Prasugrel Hydrochloride; Recombinant Proteins; Retrospective Studies; Thiophenes; Thrombosis; Ticlopidine

2013
Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Volume: 10, Issue:1

    Topics: Abciximab; Aged; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Logistic Models; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Proportional Hazards Models; Recombinant Proteins; Risk Factors; Stents; Ticlopidine

2014
Improving outcomes with bivalirudin in primary percutaneous coronary intervention.
    European heart journal, 2014, Sep-07, Volume: 35, Issue:34

    Topics: Anticoagulants; Clopidogrel; Heparin; Hirudins; Humans; Male; Myocardial Infarction; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recombinant Proteins; Thiophenes; Ticlopidine

2014
The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention.
    American heart journal, 2014, Volume: 167, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Early Medical Intervention; Female; Guideline Adherence; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Patient Transfer; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Retrospective Studies; Ticlopidine; Time-to-Treatment

2014
Impact of different antithrombotics on the microcirculation and viability of perforator-based ischaemic skin flaps in a small animal model.
    Scientific reports, 2016, 10-21, Volume: 6

    Topics: Animals; Aspirin; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Graft Survival; Heparin; Hirudins; Ischemia; Laser-Doppler Flowmetry; Male; Microcirculation; Pentoxifylline; Postoperative Complications; Rats; Rats, Wistar; Skin Diseases; Skin Transplantation; Surgical Flaps; Ticlopidine

2016
Impact of Anemia on the Risk of Bleeding Following Percutaneous Coronary Interventions in Patients ≥75 Years of Age.
    The American journal of cardiology, 2020, 04-15, Volume: 125, Issue:8

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anemia; Angina, Unstable; Anticoagulants; Antithrombins; Aspirin; Cause of Death; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug-Eluting Stents; Female; Gastrointestinal Hemorrhage; Hemorrhage; Heparin; Hirudins; Humans; Intracranial Hemorrhages; Kaplan-Meier Estimate; Male; Myocardial Infarction; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Prasugrel Hydrochloride; Proportional Hazards Models; Prospective Studies; Recombinant Proteins; Risk Assessment; Stents; Ticagrelor; Urologic Diseases

2020