clopidogrel and efavirenz

clopidogrel has been researched along with efavirenz in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (14.29)	29.6817
2010's	6 (85.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Desta, Z; Guo, Y; Ogburn, ET; Xu, C	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Astuccio, AV; Obach, RS; Walsky, RL	1
Bae, SK; Desta, Z; Flockhart, DA; Jiang, F; Kim, HS; Lee, SS; Liu, KH; Shin, JG; Shon, JH; Yeo, CW	1
Abdelhady, AM; Desta, Z; Jiang, F; Overholser, BR; Shin, JG; Yeo, CW	1
Granero, GE; Mora, MJ; Onnainty, R	1

Reviews

1 review(s) available for clopidogrel and efavirenz

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for clopidogrel and efavirenz

Article	Year
Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index. British journal of clinical pharmacology, 2013, Volume: 75, Issue:1 Topics: Alkynes; Anti-HIV Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Clopidogrel; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Genotype; Humans; Hydroxylation; Itraconazole; Male; Oxidoreductases, N-Demethylating; Phenotype; Platelet Aggregation Inhibitors; Ticlopidine	2013
Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz. Journal of clinical pharmacology, 2014, Volume: 54, Issue:1 Topics: Adult; Algorithms; Alkynes; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Chromatography, High Pressure Liquid; Clopidogrel; Computer Simulation; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 Enzyme System; DNA; Drug Interactions; Humans; Male; Models, Biological; Pharmacogenetics; Population; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Ticlopidine; Treatment Outcome; Young Adult	2014

Article

Year

Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index.

British journal of clinical pharmacology, 2013, Volume: 75, Issue:1

Topics: Alkynes; Anti-HIV Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Clopidogrel; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Genotype; Humans; Hydroxylation; Itraconazole; Male; Oxidoreductases, N-Demethylating; Phenotype; Platelet Aggregation Inhibitors; Ticlopidine

2013

Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz.

Journal of clinical pharmacology, 2014, Volume: 54, Issue:1

Topics: Adult; Algorithms; Alkynes; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Chromatography, High Pressure Liquid; Clopidogrel; Computer Simulation; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 Enzyme System; DNA; Drug Interactions; Humans; Male; Models, Biological; Pharmacogenetics; Population; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Ticlopidine; Treatment Outcome; Young Adult

2014

Other Studies

4 other study(ies) available for clopidogrel and efavirenz

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of the CYP2B66 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4* Topics: Alkynes; Alleles; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Biotransformation; Bupropion; Catalysis; Clopidogrel; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochromes b5; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyrimidines; Substrate Specificity; Ticlopidine; Triazoles; Voriconazole	2012
Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6. Journal of clinical pharmacology, 2006, Volume: 46, Issue:12 Topics: Algorithms; Alkynes; Antidepressive Agents, Second-Generation; Antifungal Agents; Area Under Curve; Benzoxazines; Bupropion; Clopidogrel; Clotrimazole; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Itraconazole; Kinetics; Microsomes, Liver; Molecular Structure; Oxazines; Platelet Aggregation Inhibitors; Raloxifene Hydrochloride; Reverse Transcriptase Inhibitors; Selective Estrogen Receptor Modulators; Selective Serotonin Reuptake Inhibitors; Sertraline; Ticlopidine; Xenobiotics	2006
Comparative Oral Drug Classification Systems: Acetazolamide, Azithromycin, Clopidogrel, and Efavirenz Case Studies. Molecular pharmaceutics, 2018, 08-06, Volume: 15, Issue:8 Topics: Acetazolamide; Administration, Oral; Alkynes; Animals; Azithromycin; Benzoxazines; Biological Assay; Biological Availability; Biopharmaceutics; Clopidogrel; Cyclopropanes; Drug Evaluation, Preclinical; Feasibility Studies; Intestinal Absorption; Intestinal Mucosa; Perfusion; Permeability; Rats; Solubility	2018