clopidogrel has been researched along with clopidogrel carboxylic acid in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, ED; Farha, MA; Gale, RT; Koteva, K; Sewell, EW; Wright, GD | 1 |
| Kauert, GF; Lindhoff-Last, E; Linnemann, B; Mani, H; Schwonberg, J; Toennes, SW; Urbanek, DA | 1 |
| Al-Zumyli, R; Arafat, T; Bulatova, NR; Yousef, AM | 1 |
| Lindhoff-Last, E; Linnemann, B; Mani, H; Schwonberg, J; Toennes, SW | 1 |
| Ciuca, V; Gheorghe, M; Iordachescu, A; Rizea Savu, S; Silvestro, L; Tarcomnicu, I; Tudoroniu, A | 1 |
| Adams, MP; Cooper, WD; Cushing, DJ; Kowey, PR; Machatha, S; Mosher, GL; Souney, PF; Zhang, B | 1 |
| Brecht, K; Donzelli, M; Krähenbühl, S; Maseneni, S; Taegtmeyer, AB | 1 |
| Danielak, D; Główka, F; Karaźniewicz-Łada, M; Teżyk, A; Tuffal, G; Zaba, C | 1 |
| Elsinghorst, PW | 1 |
| Jiang, H; Li, L; Song, F; Tu, M; Wang, K; Wu, X; Xia, Z; Zhao, L; Zhou, H | 1 |
| Chen, GM; Lu, J; Shao, H; Xu, YT; Zhan, Y; Zhang, HJ | 1 |
| Court, MH; Lee, PM; Lyngby, JG | 1 |
| Adamiak-Giera, U; Czerkawska, A; Gawrońska-Szklarz, B; Jastrzębska, M; Kurzawski, M; Olędzki, S; Safranow, K | 1 |
| Tang, X; Tian, Y; Zhang, Y; Zhang, YY; Zhang, Z | 1 |
1 review(s) available for clopidogrel and clopidogrel carboxylic acid
| Article | Year |
|---|---|
Quantitative determination of clopidogrel and its metabolites in biological samples: a mini-review.
Topics: Chromatography, Liquid; Clopidogrel; Humans; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2013 |
2 trial(s) available for clopidogrel and clopidogrel carboxylic acid
| Article | Year |
|---|---|
Smoking behaviour modulates pharmacokinetics of orally administered clopidogrel.
Topics: Administration, Oral; Adult; Area Under Curve; Body Weight; Clopidogrel; Drug Interactions; Half-Life; Humans; Male; Platelet Aggregation Inhibitors; Smoking; Ticlopidine | 2008 |
Pharmacokinetics and platelet aggregation inhibitory effects of a novel intravenous formulation of clopidogrel in humans.
Topics: Adult; beta-Cyclodextrins; Biotransformation; Clopidogrel; Dose-Response Relationship, Drug; Drug Compounding; Excipients; Female; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2012 |
11 other study(ies) available for clopidogrel and clopidogrel carboxylic acid
| Article | Year |
|---|---|
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites.
Topics: Clopidogrel; Drug Design; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Molecular Structure; Oxidation-Reduction; Teichoic Acids; Ticlopidine | 2014 |
Determination of clopidogrel main metabolite in plasma: a useful tool for monitoring therapy?
Topics: Aged; Chromatography, High Pressure Liquid; Clopidogrel; Female; Humans; Male; Mass Spectrometry; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Variability of residual platelet function despite clopidogrel treatment in patients with peripheral arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Patient Compliance; Peripheral Vascular Diseases; Platelet Aggregation; Ticlopidine | 2010 |
Development and validation of an HPLC-MS/MS method to quantify clopidogrel acyl glucuronide, clopidogrel acid metabolite, and clopidogrel in plasma samples avoiding analyte back-conversion.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Clopidogrel; Humans; Reproducibility of Results; Tandem Mass Spectrometry; Ticlopidine | 2011 |
Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites.
Topics: Cell Survival; Clopidogrel; Colony-Forming Units Assay; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Humans; Myeloid Progenitor Cells; Peroxidase; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
HPLC-MS/MS method for the simultaneous determination of clopidogrel, its carboxylic acid metabolite and derivatized isomers of thiol metabolite in clinical samples.
Topics: Aged; Chromatography, High Pressure Liquid; Clopidogrel; Drug Stability; Female; Humans; Isomerism; Linear Models; Male; Reproducibility of Results; Sulfhydryl Compounds; Tandem Mass Spectrometry; Ticlopidine | 2012 |
In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
Topics: Animals; Biotransformation; Clopidogrel; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Hepatocytes; Humans; Hydrolysis; Kidney; Madin Darby Canine Kidney Cells; Organic Anion Transport Protein 1; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Ticlopidine; Transfection | 2014 |
Metabolic Interaction Potential between Clopidogrel and Sulfonylurea Antidiabetic Agents: Effects on Clopidogrel Bioactivation.
Topics: Carboxylic Ester Hydrolases; Clopidogrel; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9 Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Gliclazide; Glipizide; Humans; Hypoglycemic Agents; Intestines; Liver; Microsomes; Sulfonylurea Compounds; Ticlopidine | 2016 |
Validation of a method for quantitation of the clopidogrel active metabolite, clopidogrel, clopidogrel carboxylic acid, and 2-oxo-clopidogrel in feline plasma.
Topics: Animals; Cats; Chromatography, High Pressure Liquid; Clopidogrel; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2017 |
Impact of selected genetic factors on clopidogrel inactive metabolite level and antiplatelet response in patients after percutaneous coronary intervention.
Topics: Aged; Alleles; Chromatography, High Pressure Liquid; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine | 2021 |
Development and validation of a sensitive LC-MS/MS method for simultaneous analysis of clopidogrel and simvastatin and their main metabolites in beagles: Application to pharmacokinetic drug interactions.
Topics: Animals; Chromatography, Liquid; Clopidogrel; Dogs; Drug Interactions; Pharmaceutical Preparations; Reproducibility of Results; Simvastatin; Tandem Mass Spectrometry | 2023 |