cloperastine has been researched along with piperidines in 20 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (15.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (15.00) | 29.6817 |
2010's | 7 (35.00) | 24.3611 |
2020's | 7 (35.00) | 2.80 |
Authors | Studies |
---|---|
Borzani, M; Scotti, L | 1 |
Allegra, L; Bossi, R | 1 |
Canti, G; Franco, P; Nicolin, A | 1 |
Aliprandi, P; Bernorio, S; Carrara, M; Castelli, C; Dell'Abate, E | 1 |
Otsuka, M; Sakata, Y; Shiraishi, S; Sumikawa, T; Tanabe, E; Tokudome, Y | 1 |
Fawcett, JP; Gu, J; Jiang, Y; Li, H; Wang, J; Zhang, C | 1 |
Shirasaki, T; Soeda, F; Takahama, K; Yamamoto, G | 2 |
Honda, S; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K | 1 |
Hirakawa, E; Inoue, M; Shirasaki, T; Soeda, F; Takahama, K | 1 |
Barbas, C; Ceppa, F; García, A; Pellati, F; Rupérez, FJ | 1 |
Hayek, LF; Perez-Dueñas, B; Sanz-Cuesta, M; Serrano, M; Villaronga, M | 1 |
Fujiwara, K; Namekata, I; Ohtsuki, A; Oka, T; Takahara, A; Tanaka, H | 1 |
Civardi, C; Collini, A; Enrico, E; Geda, C; Maggio, M | 1 |
Guo, X; Jiang, Z; Lun, J; Song, Y; Zhao, P | 1 |
Cui, N; Jiang, C; Johnson, CM; Wu, Y; Xing, H | 1 |
Cheng, QZ; Fu, HZ; Guo, YF; Liu, HY; Xia, HY; Yu, SS; Zheng, SS; Zhong, ZH | 1 |
Ebihara, M; Fujimoto, Y; Imamura, T; Matsumoto, N; Oishi, S; Okada, T | 1 |
Ekins, S; Puhl, AC; Urbina, F | 1 |
Huang, J; Li, F; Shao, L; Shi, G; Wang, X; Wu, K; Yan, J; Yang, L; Yin, X | 1 |
4 review(s) available for cloperastine and piperidines
Article | Year |
---|---|
Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents.
Topics: Adolescent; Adult; Aged; Antitussive Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Female; Humans; Lung Diseases; Male; Middle Aged; Patient Selection; Piperidines; Propylene Glycols; Stereoisomerism; Treatment Outcome | 2004 |
[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats].
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Cyclopentanes; Disease Models, Animal; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Male; Piperidines; Rats; Rats, Wistar | 2010 |
[Is the GIRK channel a possible target in the development of a novel therapeutic drug of urinary disturbance?].
Topics: Animals; Antitussive Agents; Brain; Cerebral Infarction; Dextromethorphan; Drug Design; Dysuria; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Molecular Targeted Therapy; Piperidines; Rats; Serotonin; Urinary Bladder, Overactive | 2011 |
Recent advances in drug repurposing using machine learning.
Topics: Alzheimer Disease; Antineoplastic Agents; Antiviral Agents; Clemastine; Computational Biology; COVID-19 Drug Treatment; Dipyridamole; Drug Repositioning; Humans; Hydroxychloroquine; Lenalidomide; Machine Learning; Neoplasms; Neuroprotective Agents; Piperazines; Piperidines; Protein Kinase Inhibitors | 2021 |
2 trial(s) available for cloperastine and piperidines
Article | Year |
---|---|
[Cloperastine fendizoate in the treatment of cough-producing diseases in pediatrics].
Topics: Acute Disease; Antitussive Agents; Bronchitis; Child; Child, Preschool; Clinical Trials as Topic; Cough; Double-Blind Method; Female; Humans; Male; Piperidines; Random Allocation | 1988 |
Clinical trials with the new antitussive levodropropizine in adult bronchitic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitussive Agents; Benzophenones; Bronchitis; Clinical Trials as Topic; Cough; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Piperidines; Propylene Glycols | 1988 |
14 other study(ies) available for cloperastine and piperidines
Article | Year |
---|---|
[The pharmacologic activity of 1(2-(p-chloro-alpha-phenylbenzyloxy)ethyl)piperidine (cloperastine)].
Topics: Animals; Antitussive Agents; Female; Guinea Pigs; Histamine H1 Antagonists; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Sleep | 1983 |
Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Combinations; Drug Stability; Hardness; Hydrogen Bonding; Microscopy, Electron, Scanning; Phase Transition; Piperidines; Powders; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; Temperature; Time Factors | 2007 |
Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Acetaminophen; Caffeine; Chlorpheniramine; Chromatography, Liquid; Evaluation Studies as Topic; Humans; Male; Piperidines; Pseudoephedrine; Tandem Mass Spectrometry | 2010 |
Ameliorating effects of cloperastine on dysfunction of the urinary bladder caused by cerebral infarction in conscious rats.
Topics: Animals; Antitussive Agents; Ataxia; Dextromethorphan; Diagnostic Techniques, Urological; Infarction, Middle Cerebral Artery; Male; Piperidines; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2009 |
Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol.
Topics: Animals; Antitussive Agents; Avoidance Learning; Brain-Derived Neurotrophic Factor; Diethylstilbestrol; Endocrine Disruptors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Hippocampus; Learning Disabilities; Male; Mice; Neuroprotective Agents; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Serotonin, 5-HT1A | 2014 |
Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate.
Topics: Chromatography; Chromatography, High Pressure Liquid; Drug Contamination; Gas Chromatography-Mass Spectrometry; Mutagenicity Tests; Piperidines | 2012 |
Cloperastine-based cough syrup and acute dystonic reactions.
Topics: Antitussive Agents; Child; Cough; Dystonia; Female; Humans; Piperidines | 2012 |
Effects of the antitussive drug cloperastine on ventricular repolarization in halothane-anesthetized guinea pigs.
Topics: Action Potentials; Amino Alcohols; Animals; Animals, Inbred Strains; Anti-Arrhythmia Agents; Antitussive Agents; Diphenhydramine; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Ventricles; HEK293 Cells; Humans; Long QT Syndrome; Membrane Potentials; Osmolar Concentration; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Recombinant Proteins; Structure-Activity Relationship | 2012 |
Induced hemichorea by cloperastine overuse.
Topics: Chorea; Humans; Piperidines | 2020 |
Enantioselective LC-MS/MS method for the determination of cloperastine enantiomers in rat plasma and its pharmacokinetic application.
Topics: Animals; Chromatography, Liquid; Limit of Detection; Piperidines; Rats; Stereoisomerism; Tandem Mass Spectrometry; Tissue Distribution | 2020 |
The antitussive cloperastine improves breathing abnormalities in a Rett Syndrome mouse model by blocking presynaptic GIRK channels and enhancing GABA release.
Topics: Animals; Antitussive Agents; Brain Stem; Dose-Response Relationship, Drug; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Mice; Mice, Transgenic; Organ Culture Techniques; Piperidines; Potassium Channel Blockers; Presynaptic Terminals; Rats; Respiration; Rett Syndrome | 2020 |
Identification and quantification of five impurities in cloperastine hydrochloride.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Magnetic Resonance Spectroscopy; Piperidines | 2021 |
Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Fibroblast Growth Factors; Gene Expression; Gene Expression Regulation, Neoplastic; HeLa Cells; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Neoplasms; Piperidines; Receptors, Histamine H1 | 2021 |
Efficient synthesis of bepotastine and cloperastine intermediates using engineered alcohol dehydrogenase with a hydrophobic pocket.
Topics: Alcohol Dehydrogenase; Biocatalysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Piperidines; Pyridines; Stereoisomerism | 2021 |