cloperastine and diphenhydramine hydrochloride

cloperastine has been researched along with diphenhydramine hydrochloride in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Borzani, M; Scotti, L1
Allegra, L; Bossi, R1
Canti, G; Franco, P; Nicolin, A1
Aliprandi, P; Bernorio, S; Carrara, M; Castelli, C; Dell'Abate, E1
Otsuka, M; Sakata, Y; Shiraishi, S; Sumikawa, T; Tanabe, E; Tokudome, Y1
Shirasaki, T; Soeda, F; Takahama, K; Yamamoto, G2
Hirakawa, E; Inoue, M; Shirasaki, T; Soeda, F; Takahama, K1
Hayek, LF; Perez-DueƱas, B; Sanz-Cuesta, M; Serrano, M; Villaronga, M1
Fujiwara, K; Namekata, I; Ohtsuki, A; Oka, T; Takahara, A; Tanaka, H1
Cui, N; Jiang, C; Johnson, CM; Wu, Y; Xing, H1

Reviews

2 review(s) available for cloperastine and diphenhydramine hydrochloride

ArticleYear
Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents.
    Drugs under experimental and clinical research, 2004, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antitussive Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Female; Humans; Lung Diseases; Male; Middle Aged; Patient Selection; Piperidines; Propylene Glycols; Stereoisomerism; Treatment Outcome

2004
[Is the GIRK channel a possible target in the development of a novel therapeutic drug of urinary disturbance?].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:4

    Topics: Animals; Antitussive Agents; Brain; Cerebral Infarction; Dextromethorphan; Drug Design; Dysuria; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Molecular Targeted Therapy; Piperidines; Rats; Serotonin; Urinary Bladder, Overactive

2011

Trials

2 trial(s) available for cloperastine and diphenhydramine hydrochloride

ArticleYear
[Cloperastine fendizoate in the treatment of cough-producing diseases in pediatrics].
    Minerva pediatrica, 1988, Volume: 40, Issue:5

    Topics: Acute Disease; Antitussive Agents; Bronchitis; Child; Child, Preschool; Clinical Trials as Topic; Cough; Double-Blind Method; Female; Humans; Male; Piperidines; Random Allocation

1988
Clinical trials with the new antitussive levodropropizine in adult bronchitic patients.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitussive Agents; Benzophenones; Bronchitis; Clinical Trials as Topic; Cough; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Piperidines; Propylene Glycols

1988

Other Studies

7 other study(ies) available for cloperastine and diphenhydramine hydrochloride

ArticleYear
[The pharmacologic activity of 1(2-(p-chloro-alpha-phenylbenzyloxy)ethyl)piperidine (cloperastine)].
    Bollettino chimico farmaceutico, 1983, Volume: 122, Issue:8

    Topics: Animals; Antitussive Agents; Female; Guinea Pigs; Histamine H1 Antagonists; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Sleep

1983
Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations.
    International journal of pharmaceutics, 2007, Apr-20, Volume: 335, Issue:1-2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Combinations; Drug Stability; Hardness; Hydrogen Bonding; Microscopy, Electron, Scanning; Phase Transition; Piperidines; Powders; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; Temperature; Time Factors

2007
Ameliorating effects of cloperastine on dysfunction of the urinary bladder caused by cerebral infarction in conscious rats.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:11

    Topics: Animals; Antitussive Agents; Ataxia; Dextromethorphan; Diagnostic Techniques, Urological; Infarction, Middle Cerebral Artery; Male; Piperidines; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder, Overactive; Urination

2009
Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol.
    Environmental toxicology, 2014, Volume: 29, Issue:2

    Topics: Animals; Antitussive Agents; Avoidance Learning; Brain-Derived Neurotrophic Factor; Diethylstilbestrol; Endocrine Disruptors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Hippocampus; Learning Disabilities; Male; Mice; Neuroprotective Agents; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Serotonin, 5-HT1A

2014
Cloperastine-based cough syrup and acute dystonic reactions.
    Developmental medicine and child neurology, 2012, Volume: 54, Issue:3

    Topics: Antitussive Agents; Child; Cough; Dystonia; Female; Humans; Piperidines

2012
Effects of the antitussive drug cloperastine on ventricular repolarization in halothane-anesthetized guinea pigs.
    Journal of pharmacological sciences, 2012, Volume: 120, Issue:3

    Topics: Action Potentials; Amino Alcohols; Animals; Animals, Inbred Strains; Anti-Arrhythmia Agents; Antitussive Agents; Diphenhydramine; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Ventricles; HEK293 Cells; Humans; Long QT Syndrome; Membrane Potentials; Osmolar Concentration; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Recombinant Proteins; Structure-Activity Relationship

2012
The antitussive cloperastine improves breathing abnormalities in a Rett Syndrome mouse model by blocking presynaptic GIRK channels and enhancing GABA release.
    Neuropharmacology, 2020, 10-01, Volume: 176

    Topics: Animals; Antitussive Agents; Brain Stem; Dose-Response Relationship, Drug; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Mice; Mice, Transgenic; Organ Culture Techniques; Piperidines; Potassium Channel Blockers; Presynaptic Terminals; Rats; Respiration; Rett Syndrome

2020