clonidine has been researched along with yohimbine in 1286 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 670 (52.10) | 18.7374 |
| 1990's | 394 (30.64) | 18.2507 |
| 2000's | 159 (12.36) | 29.6817 |
| 2010's | 57 (4.43) | 24.3611 |
| 2020's | 6 (0.47) | 2.80 |
| Authors | Studies |
|---|---|
| Haubrich, DR; Hlasta, DJ; Luttinger, D; Perrone, MH; Silbernagel, MJ; Ward, SJ | 1 |
| Audiau, F; Benavides, J; Guérémy, C; Le Fur, G; Renault, C; Uzan, A | 1 |
| Counsell, RE; Neubig, R; Van Dort, M | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF | 1 |
| Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Butler, RC; Chapleo, CB; Davis, JA; Doxey, JC; Higgins, SD; Myers, M; Myers, PL; Roach, AG; Smith, CF; Stillings, MR | 1 |
| Timmermans, PB; van Zwieten, PA | 2 |
| Bondinell, W; Hieble, JP; Ruffolo, RR | 1 |
| Blitzer, RD; Cornfeldt, M; Davis, L; Effland, RC; Haroutunian, V; Huger, FP; Klein, JT; Landau, E; Martin, LL; Olsen, GE; Petko, WW; Smith, CP; Wilker, JC; Wong, GS | 1 |
| Harms, GS; Lohse, MJ; Steinmeyer, R; Vilardaga, JP | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benedetti, G; Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F; Varrone, M | 1 |
| Andén, NE; Grabowska, M; Strömbom, U | 1 |
| Andén, NE; Grabowska, M | 1 |
| Doxey, JC; Smith, CF; Walker, JM | 1 |
| Doxey, JC; Everitt, J; Metcalf, G | 1 |
| Kapur, H; Mottram, DR | 1 |
| Grant, JA; Scrutton, MC | 1 |
| Fludder, JM; Leonard, BE | 1 |
| Baraban, JM; Davis, M; Redmond, DE | 1 |
| Paalzow, G; Paalzow, L | 1 |
| Strömbom, U | 1 |
| Andén, N; Grabowska, M | 1 |
| Braestrup, C; Nielsen, M | 1 |
| Davis, GA; Kohl, R | 1 |
| Leppävuori, A; Putkonen, PT; Stenberg, D | 1 |
| Dausse, J; Meyer, P; Miach, PJ | 1 |
| Constantine, JW; McShane, WK; Weeks, RA | 1 |
| Atrens, DM; Becker, FT; Hunt, GE; Paxinos, G | 1 |
| Docherty, JR; McGrath, JC | 3 |
| Tayo, FM | 1 |
| Fu, SX; Wang, LF; Zhang, SS | 1 |
| Koss, MC | 5 |
| Bartholini, G; Dubocovich, ML; Langer, SZ; Pelayo, F; Scatton, B | 1 |
| Hawkins, M; Monti, JM | 1 |
| Baumann, N; Chermat, R; Lachapelle, F; Simon, P | 1 |
| Bernthal, PJ; Koss, MC | 1 |
| Roba, J; van Dorsser, W | 1 |
| Autret, A; Beillevaire, T; Cathala, HP; Minz, M; Schmitt, H | 1 |
| Gomes, C; Svensson, TH; Trolin, G | 1 |
| Van Zwieten, PA | 2 |
| Davison, MA; Koss, MC | 1 |
| Dai, SP; Huang, HY; Xie, PG | 1 |
| Grimaud, N; Jugé, M; Petit, JY; Robert, B; Welin, L | 1 |
| Bradley, ME; Buxton, IL; Keef, KD; Zhang, L | 1 |
| Blatteis, CM; Quan, N; Ungar, AL; Xin, L | 1 |
| Klein, DC; Schaad, NC | 1 |
| Chan, CB; MacPhail, RM | 1 |
| Contin, M; Cortelli, P; Lugaresi, A; Lugaresi, E; Parchi, P; Pasquali, R; Sforza, E | 1 |
| Dinari, G; Kiro, A; Marcus, H; Zahavi, I | 1 |
| Brading, AF; Chen, HI | 1 |
| Hsieh, ST; Kubota, Y; Miyajima, T; Nakajima, M; Saito, K; Saito, N; Sano, H; Tsujino, T; Yokoyama, M | 1 |
| Lin, W; McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Kumakura, K; Ohara-Imaizumi, M | 1 |
| Kawasaki, H; Nakamura, S; Takasaki, K | 1 |
| Coupland, N; Glue, P; Nutt, DJ | 1 |
| Alam, MN; Mallick, BN | 2 |
| Charney, DS; Heninger, GR; Krystal, JH; Nagy, LM; Woods, SW | 1 |
| Goberna, R; Lucas, M; Sánchez-Margalet, V | 1 |
| Celuch, SM; Enero, MA; Ramirez, AJ | 1 |
| Kontani, H; Maruyama, I; Sakai, T | 1 |
| Ray, AK; Sarkar, PK | 1 |
| Okuma, Y; Osumi, Y; Yokotani, K | 2 |
| Nowak, G; Pilc, A; Zak, J | 1 |
| Carlson, DE; Gann, DS | 1 |
| Alburges, ME; Bylund, DB; Hunt, MA; Wamsley, JK | 1 |
| Colado, MI; Martin, MI | 1 |
| Okuma, Y; Reisine, T | 1 |
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Evans, RG; Hayes, IP; Ludbrook, J | 1 |
| Hamada, T; Hamahashi, T; Itoh, T; Kamisaki, Y; Maeda, K | 1 |
| Leidenheimer, NJ; Schechter, MD | 1 |
| Jhamandas, K; Penning, DH | 1 |
| Bapna, JS; Ramaswamy, S; Shewade, DG; Tyagi, MG | 1 |
| Ando, R; Kawamura, S; Kimura, Y; Kisara, K; Tadano, T; Yonezawa, A | 1 |
| Besson, JM; Guilbaud, G; Kayser, V | 1 |
| Sperlágh, B; Vizi, ES | 1 |
| Carratù, MR; De Serio, A; Mitolo-Chieppa, D; Navarra, P; Preziosi, P; Serio, M | 1 |
| Su, C; Su, S; Zheng, S | 1 |
| Brock, JA; Cunnane, TC | 1 |
| Lin, MT; Su, CF | 1 |
| Redman, RS; Yu, JH | 1 |
| Currie, PJ; Wilson, LM | 2 |
| Altiere, RJ; Diamond, L; Thompson, DC | 2 |
| Lasova, L; Mutafova-Yambolieva, V; Petkov, O; Staneva-Stoytcheva, D | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Kempf, J; Molines, A; Stutzman, J | 1 |
| Dawes, P; Rochford, J | 1 |
| Tao, JY; Wang, P; Xu, SY | 1 |
| Garzón, J; Sánchez-Blázquez, P | 1 |
| Black, B; Boulenger, JP; Geraci, M; Gurguis, G; Post, RM; Roscow, DB; Rubinow, DR; Tancer, ME; Uhde, TW; Vittone, B | 1 |
| Dalman, HM; Neubig, RR | 1 |
| Borbujo, J; Diéguez, G; García, JL; García-Villalón, AL; Gómez, B; Nava-Hernández, E; Valle, J | 1 |
| Chan, WF; Hui, KK; Tse, E; Yu, JL | 1 |
| Clark, JT | 1 |
| Drouva, SV; Faivre-Bauman, A; Kordon, C; Laplante, E; Loudes, C | 1 |
| Chang, MS; Chen, SA; Chiang, BN; Kuo, JS; Liu, RH; Ting, TH | 2 |
| Borda, ES; de Bracco, MM; Fernández, J; Finiasz, M; Goin, JC; Sterin-Borda, L | 1 |
| Schultheiss, A; Starke, K; Szabo, B | 1 |
| Jurkiewicz, A; Jurkiewicz, NH | 1 |
| Allgaier, C; Greber, R; Hertting, G | 1 |
| Ger, LP; Tseng, CJ; Tung, CS | 1 |
| McCook, EC; Nemeroff, CB; Seidler, FJ; Slotkin, TA | 1 |
| Berlan, M; Damase-Michel, C; Montastruc, JL; Montastruc, P; Poncet, MF; Tavernier, G; Tran, MA | 1 |
| Patel, KP | 1 |
| Edwards, SR; Smythe, GA | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Dresse, A; Massotte, L; Seutin, V; Verbanck, P | 1 |
| Corboz, M; Palmer, CI; Palmeri, A; Wiesendanger, M | 1 |
| Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J | 1 |
| Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Tibiriça, E | 1 |
| Chen, LQ; Riedel, GL; Shepherd, AP | 1 |
| Guyenet, PG; Nosjean, A | 1 |
| Mori-Okamoto, J; Namii, Y; Tatsuno, J | 1 |
| Breschi, MC; Ciucci, MA; Martinotti, E; Nieri, P; Omini, C; Pani, M | 1 |
| Fujimura, H; Oda, S; Ohneda, A; Sasaki, Y | 1 |
| Devi, K; Hrishikeshavan, HJ; Munonyedi, US; Shanbhogue, RS | 1 |
| Arce, V; Devesa, J; Diaz, MJ; Lima, L; Tresguerres, JA | 1 |
| Andorn, AC; Halaris, A; Piletz, JE; Unnerstall, JR | 1 |
| Bartha, L; Hársing, LG; Kiem, DT; Makara, GB | 1 |
| Downie, JW; Espey, MJ; Gajewski, JB | 1 |
| Chandler, SH; Katakura, N | 1 |
| Ruff, G; Rump, LC; Schollmeyer, P; Wolk, V | 1 |
| Brien, JF; Marks, GS; Nakatsu, K; Pym, J; Witte, S | 1 |
| Guenaneche, F; Lefebvre, RA; Schuurkes, JA | 1 |
| Cassinadri, M; Ferrari, F; Tampieri, A; Tartoni, PL | 1 |
| Bojö, L; Cassuto, J; Nellgård, P | 1 |
| Bhandare, PN; D'Souza, RS; Rataboli, PV | 1 |
| Harris, LT; King, KA; McCall, RB | 1 |
| Horváth, E; Jaszlits, L; Rabloczky, G | 1 |
| Atlas, D; Manolopoulos, VG; Pipili-Synetos, E; Synetos, D | 1 |
| Gleason, MM; Hieble, JP | 1 |
| Deckert, V; Elghozi, JL; Lachaud, V; Parini, A | 1 |
| Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Monassier, L; Tibiriça, E | 1 |
| Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P | 1 |
| Martinelli, B; Morrone, LA; Severini, C; Valeri, P | 1 |
| Abebe, W; Harris, KH; MacLeod, KM | 1 |
| Cumming, P; Damsma, G; Fibiger, HC; Vincent, SR | 1 |
| Dai, S; Wang, Y | 1 |
| Cristòfol, RM; Rodríguez-Farré, E | 1 |
| Heistracher, M; Prast, H | 1 |
| Fukuda, H; Mishima, A; Ono, H; Ono, S; Vasko, MR | 1 |
| Heistracher, M; Philippu, A; Prast, H | 1 |
| Pittaluga, A; Raiteri, M; Torelli, R | 1 |
| Broderick, PA | 2 |
| Foo, H; Westbrook, RF | 1 |
| Hamahashi, T; Itoh, T; Kamisaki, Y; Okada, CM | 1 |
| Grealy, M; O'Donnell, JM | 1 |
| Nakamura, T; Nomura, J; Tsujimura, R | 1 |
| Wong, CL | 2 |
| Bak, JF; Møller-Pedersen, T; Pedersen, SB; Richelsen, B | 1 |
| Ammälä, C; Arkhammar, P; Berggren, PO; Bokvist, K; Larsson, O; Rorsman, P; Wåhlander, K | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H | 1 |
| Danzebrink, RM; Gebhart, GF | 2 |
| Hamilton, CA; Jardine, E; Reid, JL; Yakubu, MA | 1 |
| Elverdin, JC; Kaniucki, MO; Perec, CJ; Stefano, FJ | 1 |
| Nakajima, M; Ueda, M | 1 |
| Opitz, K | 1 |
| Palmeri, A; Wiesendanger, M | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Hashimoto, K; Hayashi, M; Tanii, H | 1 |
| Arvat, E; Bellone, J; Brambilla, F; Camanni, F; Cella, SG; Ghigo, E; Mazza, E; Müller, EE; Revelli, E | 1 |
| Chandranath, SI; Gokhale, SD; Sharif, SI | 1 |
| Glenert, U; Nauntofte, B | 1 |
| Rouse, D; Suki, WN; Williams, S | 1 |
| Gerhardt, MA; Neubig, RR; Wade, SM | 1 |
| Halaris, A; Piletz, JE | 2 |
| Horn, PT; Kohli, JD; Mercuro, G; Orelind, ER | 1 |
| Ferrier, GR; Han, XQ | 1 |
| Crews, FT; Guzman, NJ; Pacitti, AJ; Puig, JF; Raizada, MK; Sumners, C | 1 |
| Iuvone, PM; Zawilska, J | 2 |
| George, SR; Haas, DA; Sturtridge, WC | 1 |
| Arranz, A; Arribas, S; Balfagón, G; Marín, J; Sanchez-Merino, JA | 1 |
| Kigoshi, S; Muramatsu, I; Oshita, M | 1 |
| Arnerić, SP; Tingley, FD | 1 |
| Ayajiki, K; Toda, N | 1 |
| Jäkälä, P; Lammintausta, R; Riekkinen, P; Sirviö, J | 1 |
| Iovino, M; Steardo, L; Vanacore, A | 1 |
| Arts, KS; Fujimoto, JM; Holmes, BB | 1 |
| Bolgos, G; Johnson, J; Sisson, JC | 1 |
| Bradshaw, CM; Morley, MJ; Szabadi, E | 1 |
| Bishop, VS; Hay, M | 1 |
| Cox, HS; Eisenhofer, G; Esler, MD | 1 |
| Reis, CC | 1 |
| Chugh, Y; Saha, N; Sankaranarayanan, A; Sharma, PL | 1 |
| Hertz, L; Subbarao, KV | 1 |
| Gerlich, M; Graefe, KH; Halbrügge, T; Ludwig, J | 1 |
| Burnstock, G; Ellis, JL; Kasakov, L; Vlaskovska, M | 1 |
| Atlas, D; Coupry, I; Parini, A; Podevin, RA; Uzielli, I | 1 |
| Bose, R; Smyth, DD; Stanko, CK; Vandel, MI | 1 |
| Gonon, F; Mermet, C; Suaud-Chagny, MF | 1 |
| Breuiller, M; Ferré, F; Leroy, MJ; Litime, MH; Rouot, B | 1 |
| Hosokawa, T; Kasuya, Y; Tsuchiya, Y | 1 |
| Cameron, O; Grunhaus, LJ; Haskett, RF; Hollingsworth, PJ; Pande, AC; Smith, CB | 1 |
| Burton, MD; Johnson, DC; Kazemi, H | 1 |
| Jumblatt, JE; Ohia, SE | 1 |
| Cameron, OG; Curtis, GC; Hill, EM; Hollingsworth, PJ; Lee, MA; Smith, CB | 1 |
| Liedtke, CM | 1 |
| Rattan, S; Yamato, S | 1 |
| Minneman, KP; Wilson, KM | 1 |
| De Sarro, GB; Nistico', G | 1 |
| Christensen, HD; Koss, MC; Mutzig, M | 1 |
| de Groat, WC; Somogyi, GT | 1 |
| Freedman, RR; Sabharwal, SC; Woodward, S | 1 |
| Culp, DJ; Graham, LA; Marin, MG; McBride, RK | 1 |
| Klaassen, AB; Rodrigues de Miranda, JF; Van Ginneken, CA; Van Megen, YJ; Wentges, BT | 1 |
| Barrett, JA; Edinger, H; Siegel, A | 1 |
| Berlan, M; Estan, L; Montastruc, JL; Senard, JM; Tran, MA | 1 |
| Hamilton, CA; Howie, CA; Jardine, E; Reid, JL; Yakubu, MA | 1 |
| Smith, JB | 1 |
| Camargo, LA; De Luca Junior, LA; Ferrari, AC; Menani, JV; Renzi, A; Saad, WA | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Bian, RL; Lin, B; Mao, LG; Zhao, MH; Zheng, XF | 1 |
| Gross, G; Hanft, G | 1 |
| Izenwasser, S; Kornetsky, C | 1 |
| Ivankovich, AD; Kroin, JS; Lubenow, TR; McCarthy, RJ; Penn, RD | 2 |
| Bevan, JA; Oriowo, MA | 1 |
| Bugajski, J; Gadek-Michalska, A; Połczyńska-Konior, G; Turoń, M | 1 |
| Masuda, Y; Mollace, V; Nisticò, G; Pelaggi, T | 1 |
| Clarenbach, P; Kanno, O | 1 |
| Chahl, LA | 1 |
| Andersson, KE; Hedlund, H; Larsson, B | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Chin, WP; Imai, S; Nakagawa, Y; Nakahara, H | 1 |
| Lepor, H; Shapiro, E | 1 |
| Chance, WT | 1 |
| Dresse, A; Scuvée-Moreau, J | 1 |
| Nance, PW; Sawynok, J | 1 |
| Shaikh, IM; Skala, JP | 1 |
| Atlas, D; Diamant, S; Fales, HM; Pannell, L | 1 |
| Coffman, JD; Cohen, RA | 2 |
| Ilhan, M; Kayaalp, SO; Sarioğlu, Y | 1 |
| Chen, YF; Jin, HK; Oparil, S; Wyss, JM; Yang, RH | 1 |
| Hester, RK; Satake, N; Shibata, S | 1 |
| Riou, JP; Vidal, H | 1 |
| Kotecha, N; Neild, TO | 1 |
| Li, DX; Shen, GS | 1 |
| Angioy, AM; Barbarossa, IT; Crnjar, R; Liscia, A | 1 |
| Hadjiconstantinou, M; Krajnc, D; Neff, NH; Rossetti, Z | 1 |
| Kuczenski, R; Segal, DS; Swick, D | 1 |
| Kazmi, SM; Mishra, RK | 1 |
| Anderson, RJ; Dillingham, MA | 1 |
| Gelenberg, AJ; Lydiard, RB; Wolfe, N | 1 |
| Felder, RB; Feldman, PD | 2 |
| Imura, H; Iwamori, M; Kosugi, S; Mori, T; Nagai, Y | 1 |
| Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Costa, LG; Murphy, SD; Olibet, G; Wu, DS | 1 |
| Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC | 1 |
| Luo, ZP; Yang, XM; Zhou, JH | 4 |
| Collins, JG; Kitahata, LM; Kumeta, Y; Murata, K; Nakagawa, I | 1 |
| Reimann, W; Schneider, F | 1 |
| Komidori, H; Nuki, C; Takasaki, K; Yamamoto, R | 1 |
| Harris, JC; Kehoe, P | 1 |
| Fujiwara, M; Mine, K; Okada, M | 1 |
| Gotoh, K; Hori, M; Inoue, M; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H | 1 |
| Limberger, N; Mayer, A; Singer, EA; Starke, K; Valenta, B; Zier, G | 1 |
| Emilien, G | 1 |
| Chen, HI; Kao, SJ; Shen, CY; Wang, D | 1 |
| Kendall, DA; Robinson, JP | 1 |
| Galitzky, J; Paris, H; Senard, JM | 1 |
| Arrivas, S; Balfagon, G; Barrus, MT; Capilla, MI; Marin, J; Rosa de Sagarra, M | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 2 |
| Coviello, A; Gamundi, SS; Proto, MC | 1 |
| Chernesky, CE; Chou, TC; Felsen, D; Marion, DN; Somers, WJ; Vaughan, ED | 1 |
| Daviaud, D; Mauriège, P; Paris, H; Sénard, JM | 1 |
| Berlan, M; Galitzky, J; Lafontan, M; Paris, H | 1 |
| Carvalho, F; Gonçalves, J; Guimarães, S | 1 |
| De Sarro, A; De Sarro, GB | 1 |
| File, SE; Johnston, AL | 1 |
| Allgaier, C; Habermann, E; Hertting, G; Nakov, R; Wurster, S | 1 |
| Carmel, M; Corcos, J; Galeano, C; Jubelin, B | 1 |
| García-Sevilla, JA; Giralt, MT | 1 |
| Grenhoff, J; Svensson, TH | 1 |
| Boucher, M; Chapuy, E; Duchêne-Marullaz, P; Lefebvre, MA; Mignot, A | 1 |
| Enna, SJ; Nomura, S; Pilc, A; Vetulani, J | 1 |
| Kondo, S; Latifpour, J; Morita, T; O'Hollaren, B; Weiss, RM | 1 |
| Kadota, K; Kuga, T; Moroi, K | 1 |
| Coupry, I; Koenig, E; Lachaud, V; Parini, A; Podevin, RA | 1 |
| Badia, A; Sallés, J | 1 |
| Ladwein, E; Szrama, E; Wessler, I | 1 |
| Carpéné, C; Lafontan, M; Langin, D; Saulnier-Blache, JS | 1 |
| Curtis-Prior, PB; Tan, S | 3 |
| Allgaier, C; Hertting, G; Jäger, T | 1 |
| Ferrari, F; Mangiafico, V; Monti, A; Tartoni, PG | 1 |
| Callaway, E; Halliday, R; Lannon, R | 1 |
| Chover, AJ; Esteban, J; Gibert-Rahola, J; Micó, JA; Sánchez, PA | 1 |
| Hedler, L; Starke, K; Szabo, B | 1 |
| Graefe, KH; Halbrügge, T; Wölfel, R | 1 |
| Carenzi, A; Chiarino, D; Napoletano, M; Reggiani, A; Sala, A; Sala, R | 1 |
| Butkhuzi, SM; Kolchin, VV; Moroz, BT; Sakvarelidze, ZA; Zaĭtsev, AA | 1 |
| Ben-Zvi, Z; Garty, M; Hurwitz, A | 1 |
| Morita, T; Suzuki, T; Tsuchida, S; Wada, I | 1 |
| Berlan, M; Lafontan, M; Montastruc, P; Taouis, M | 1 |
| Tung, CS; Yin, TH | 1 |
| Giesen-Crouse, E; Imbs, JL; Krieger, JP; Schmidt, M | 1 |
| Chiba, S; Haruta, K; Homma, N; Horiuchi, A; Iwatsuki, K | 1 |
| Cheema, IR; Peoples, B; Rahmani, MA; Riley, SR; Sen, S | 1 |
| Blevins, LS; Paul, DJ; Williams, CA | 1 |
| Cheema, IR; Peoples, B; Rahmani, MA; Sen, S | 1 |
| Hölting, T; Limberger, N; Starke, K | 1 |
| Harris, RA; Peris, J; Zahniser, NR | 1 |
| Atlas, D; Diamant, S; Eldor, A | 1 |
| Baldwin, JJ; deSolms, SJ; Guare, JP; Huff, JR; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM | 1 |
| Arner, P; Engfeldt, P; Hellmér, J; Ostman, J; Wennlund, A | 1 |
| Boyes, WK; Moser, VC | 1 |
| Cusolito, S; Donowitz, M; el Sabban, ME; Homaidan, FR; Sharp, WG; Weiland, GA; Wicks, J | 1 |
| Jørum, E | 1 |
| Frambach, DA; Valentine, JL; Weiter, JJ | 1 |
| Beresford, IJ; Clark, CR; Hall, MD; Hill, RG; Hughes, J | 1 |
| Lattimer, N; Rhodes, KF; Sharma, S; Ward, TJ; Waterfall, JF; White, JF | 1 |
| Carpene, C; de Pablos, I; Moratinos, J; Reverte, M | 1 |
| Hori, M; Inoue, M; Iwai, K; Iwakura, K; Kagiya, T; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Jiang, Q; Porreca, F; Sheldon, RJ | 1 |
| Bicknell, RJ; Brown, D; Chapman, C; Zhao, BG | 1 |
| Jaim-Etcheverry, G; Landa, ME; Rubio, MC | 1 |
| Bonacci, F; De Sarro, GB; Nisticò, G | 1 |
| Armah, BI | 1 |
| Hamilton, CA; Howie, CA; Reid, JL; Yakubu, MA | 1 |
| Czuczwar, SJ; Löscher, W | 1 |
| Blandford, DE; Smyth, DD | 1 |
| Abó, V; Barbeito, L; D'Angelo, L; Jantos, H; Monti, JM | 1 |
| Fujiwara, Y; Kazahaya, Y; Otsuki, S; Sandyk, R; Takeda, T | 1 |
| Akasu, T; Nishimura, T; Tokimasa, T; Tsurusaki, M | 1 |
| Huang, ZX; Ma, RC; Ou, L; Shao, QL; Wu, RL | 1 |
| Ascioti, C; Bagetta, G; de Sarro, GB; Libri, V; Nisticò, G | 2 |
| Maura, G; Pittaluga, A; Raiteri, M; Ulivi, M | 1 |
| Bousquet, P; Feldman, J; Tibirica, E | 1 |
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| Bischoff, FP; Braeken, M; Kennis, LE; Leysen, JE; Love, CJ; Megens, AA; Mertens, CJ; Pieters, S; Van den Keybus, FA | 1 |
| Brandeis, D; Callaway, E; Halliday, R; Herzig, K; Naylor, H; Yano, L | 1 |
| Lutz, EA; Shannon, HE | 1 |
| Neuman, MI; Shannon, M | 1 |
| Hayashi, Y; Kagawa, K; Kishi, Y; Kita, T; Mammoto, T; Mashimo, T; Takada, K | 1 |
| Camilleri, M; Malcolm, A | 1 |
| Calzoni, F; Ceroni, L; Cortelli, P; Gambineri, A; Gnudi, U; Menozzi, R; Pasquali, R; Rio, GD; Sinisi, R; Vicennati, V | 1 |
| Dohi, S; Iida, H; Iida, M; Takenaka, M | 1 |
| Ciranna, L; Li Volsi, G; Licata, F; Santangelo, F | 1 |
| Dobie, DJ; Peskind, ER; Petrie, EC; Raskind, MA; Veith, RC | 1 |
| Benamour, K; Chang-Fong, J; Cussac, M; Morand, JM; Szymonski, B; Thomasson, F | 1 |
| Bousquet, P; Brasili, L; Dontenwill, M; Giannella, M; Greney, H; Lugnier, C; Magnier, C; Maranca, F; Pigini, M; Quaglia, W; Rascente, C; Ronde, P | 1 |
| Burton, DD; Camilleri, M; Fett, SL; Kost, L; Malcolm, A; Zinsmeister, AR | 1 |
| Eisenach, JC; Li, X; Pan, HL; Paqueron, X; Zhao, Z | 1 |
| Bradshaw, CM; Phillips, MA; Szabadi, E | 2 |
| Baldwin, J; Chang, CH; Ernsberger, P; Gold, G; Ivanov, TR; Jones, JC; Pickard, RT; Piletz, JE; Reis, DJ; Roth, B; Sharp, JD; Zhu, H | 1 |
| de Arruda Camargo, LA; dos Santos, TA; Ferreira, AC; Guarda, IF; Neto, AF; Saad, WA | 1 |
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| Bosmans, E; Egyed, B; Kenis, G; Lin, A; Maes, M | 1 |
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| Brustein, E; Chau, C; Giroux, N; Marcoux, J; Reader, TA; Rossignol, S | 1 |
| Giroux, N; Reader, TA; Rossignol, S | 1 |
| Lelieveld, H; Nieveen, M; Ponce, MC; Steffens, A; van den Thillart, G; Van Raaij, M; Vianen, G; Zaagsma, J | 1 |
| Bantel, C; Eisenach, JC; Li, X; Paqueron, X; Tobin, JR; Voytko, ML | 1 |
| Miranda, HF; Pinardi, G; Sierralta, F | 1 |
| Chaudry, IH; Koo, DJ; Ornan, DA; Wang, P; Yang, S; Zhou, M | 1 |
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| Chao, HM; Osborne, NN | 1 |
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| Drummond, PD | 2 |
| Brodde, OE; Dhein, S; Giessler, C; Silber, RE; Wangemann, T | 1 |
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| Carvajal, A; Donoso, MV; Huidobro-Toro, JP; Koenig, CS; Paredes, A; Tomic, A | 1 |
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| Guo, S; Hisamitsu, T; Jiao, Y; Umezawa, T | 1 |
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| Chlopicki, S; Gryglewski, RJ; Kozlovski, VI | 1 |
| Lee, B; Platt, DM; Spealman, RD; Tiefenbacher, S | 1 |
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| Diedrich, A; Gross, V; Jordan, J; Luft, FC; Obst, M; Plehm, R; Tank, J | 1 |
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| Braun-Dullaeus, RC; Marquetant, R; Schmeisser, A; Schwencke, C; Strasser, RH; Weinbrenner, C | 1 |
| Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H | 1 |
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| Ignatowski, TA; Reynolds, JL; Spengler, RN; Sud, R | 1 |
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| Fahim, M; Fazli-Tabaei, S; Khoshbaten, A | 1 |
| Gray, KT; Ventura, S | 1 |
| Bay, KD; Garcia-Rill, E; Good, CH; Mamiya, K; Skinner, RD | 1 |
| Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
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| Feliu-Mojer, M; Jiménez-Rivera, CA; Vázquez-Torres, R | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Dohi, S; Iida, H; Oda, A; Osawa, Y; Tanahashi, S; Yamaguchi, S | 1 |
| Kardan, A; Mehr, SE; Samini, M | 1 |
| Ji, JZ; Ji, XH; Li, BM; Zhang, H | 1 |
| Gyires, K; Kató, E; Lipták, L; Mátyus, P; Rónai, AZ; Shujaa, N | 1 |
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| Albarrán-Juárez, JA; Centurión, D; Görnemann, T; Lozano-Cuenca, J; Pertz, HH; Villalón, CM | 1 |
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| Bhuiyan, ME; Cui, H; Gouraud, SS; Kohsaka, A; Maeda, M; Takagishi, M; Waki, H; Yamazaki, T | 1 |
| Hu, CP; Jiang, GL; Jiang, QT; Li, YJ; Peng, J; Zhang, YM | 1 |
| Bains, JS; Kuzmiski, JB; Pittman, QJ | 1 |
| Bilge, SS; Bostanci, MO; Bozkurt, A; Ciftcioglu, E; Dilek, A; Güldogus, F; Ilkaya, F; Ulger, F | 1 |
| Barresi, M; Caldera, M; Grasso, C; Li Volsi, G; Licata, F; Santangelo, F | 1 |
| Doihara, H; Ito, H; Kawabata-Shoda, E; Kojima, R; Nozawa, K; Yokoyama, T | 1 |
| Mokha, SS; Nag, S | 1 |
| Hamasaki, T; Huang, J; Ozoe, Y | 1 |
| Gong, H; Li, Z; Liu, G; Liu, H; Liu, Z; Yang, X | 1 |
| Arszol, C; Bartenstein, P; Böning, G; Cumming, P; Josef Gildehaus, F; Mille, E; Rominger, A; Wängler, B | 1 |
| Heydari, F; Mehr, SE; Samini, M | 1 |
| Dukat, M; Scheinin, M; Vainio, M; Young, S | 1 |
| Gong, H; Li, Z; Liu, G; Liu, Q; Liu, Z; Yang, X | 1 |
| Chopde, CT; Gahane, AY; Kotagale, NR; Taksande, BG; Ugale, RR | 1 |
| Bilanishvili, I; Chachua, T; Khizanishvili, N; Nanobashvili, Z | 1 |
| Ejtemaeimehr, Sh; Fatemeh, A; Mohammadi, A; Naghizadeh, MM; Zangeneh, FZ | 1 |
| Bao, JY; Huang, HW; Huang, Y; Peng, YP; Qiu, YH; Xiao, J | 1 |
| Cowan, A; Hirsch, DD; Kim, J; Lisek, R; Rawls, SM; Raymondi, N; Rosenthal, A | 1 |
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| Andurkar, SV; Bhalla, S; Gulati, A | 1 |
| Chopde, CT; Hirani, K; Kokare, DM; Kotagale, NR; Mali, PD; Nakhate, KT; Subhedar, NK; Taksande, BG; Ugale, RR | 1 |
| Bruzzone, A; Gass, H; Lanari, C; Lüthy, IA; Piñero, CP; Rojas, P; Romanato, M | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Aozuka, Y; Morimoto, Y; Shibata, Y | 1 |
| García-Bueno, B; Hinojosa, AE; Leza, JC; Madrigal, JL | 1 |
| Dong, R; Feng, X; Li, W; Liu, J; Wang, H; Xu, J; Yu, B; Zhang, F | 1 |
| Piri, M; Zarrindast, MR | 1 |
| Muck-Šeler, D; Pivac, N; Švob Štrac, D | 1 |
| Ishii-Nozawa, R; Mita, M; Shoji, M; Takeuchi, K | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Edwards, S; Koob, GF; Park, PE; Schlosburg, JE; Schulteis, G; Vendruscolo, LF | 1 |
| Banafshe, HR; Jafari-Sabet, M; Khodadadnejad, MA | 1 |
| Bahremand, A; Dehpour, AR; Moezi, L; Shafaroodi, H | 1 |
| Lonstein, JS; Olszewicz, J; Piasecki, CC; Smith, CD; Weera, M | 1 |
| Barry, DM; Du, JQ; Huo, FQ; Qu, CL; Tang, JS; Xu, FY; Xu, WJ; Zhao, Y; Zhu, JX | 1 |
| Guo, LJ; Li, CJ; Li, HG; Lv, Q; Xu, XL; Zhou, M | 1 |
| Hodges, GJ; Sparks, PA | 1 |
| Danyali, F; Ebrahimi-Ghiri, M; Oryan, S; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Jung, JS; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW | 1 |
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| Malaty, IA; Malaty, J | 1 |
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| Bertoglio, LJ; Gazarini, L; Piornedo, RR; Stern, CA; Takahashi, RN | 1 |
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| Bahremand, A; Bahremand, T; Dehpour, AR; Ebrahimi, A; Nasrabady, SE; Payandemehr, B; Rahimian, R; Sharifzadeh, M | 1 |
| Hashemi-Hezaveh, SM; Sheidadoust, H; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
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| Ebrahimi-Ghiri, M; Nasehi, M; Zamanparvar, M; Zarrindast, MR | 1 |
| Bashiri, H; Rezayof, A; Sahebgharani, M; Tavangar, SM; Zarrindast, MR | 1 |
| Nasehi, M; Norozpour, Y; Sabouri-Khanghah, V; Torabi-Nami, M; Zarrindast, MR | 1 |
| Beiranvand, A; Moghaddasi, M; Nasehi, M; Zarrindast, MR | 1 |
| Hellmann-Regen, J; Otte, C; Renneberg, B; Roepke, S; Rombold, F; Wingenfeld, K | 1 |
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| Babakordi, F; Elyasi, L; Hooshmand, E; Jahanshahi, M; Nikmahzar, E | 1 |
| Kuzmenko, NV; Pliss, MG; Tsyrlin, VA | 1 |
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| Bertoglio, LJ; Franzen, JM; Giachero, M; Marin, FN; Molina, VA; Troyner, F | 1 |
| Abelson, KSP; Kanui, TI; Mwobobia, RM | 1 |
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20 review(s) available for clonidine and yohimbine
| Article | Year |
|---|---|
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.
Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses | 1982 |
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Molecular Conformation; Molecular Structure; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1995 |
Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders.
Topics: Anxiety; Clonidine; Depression; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hydrocortisone; Norepinephrine; Receptors, Neurotransmitter; Yohimbine | 1992 |
Evidence for hypothalamo-growth hormone dysfunction in panic disorder: profile of growth hormone (GH) responses to clonidine, yohimbine, caffeine, glucose, GRF and TRH in panic disorder patients versus healthy volunteers.
Topics: Caffeine; Clonidine; Glucose; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamus; Panic Disorder; Thyrotropin-Releasing Hormone; Yohimbine | 1992 |
The role of brain and spinal cord norepinephrine in autoanalgesia.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain; Clonidine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Tolerance; Electroshock; Fear; Hydroxyindoleacetic Acid; Male; Methysergide; Nociceptors; Norepinephrine; p-Chloroamphetamine; Phenoxybenzamine; Phentolamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Spinal Cord; Time Factors; Tryptophan; Yohimbine | 1986 |
Neural and molecular mechanisms in anxiety.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Carbolines; Clonidine; Disease Models, Animal; Forecasting; Haplorhini; Humans; Locus Coeruleus; Piperoxan; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Research Design; Yohimbine | 1985 |
Central nervous system mechanisms in blood pressure control.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Disease Models, Animal; Ganglia, Sympathetic; Half-Life; Hypothalamus; Models, Neurological; Naloxone; Neurons; Nitroprusside; Norepinephrine; Phenylethanolamine N-Methyltransferase; Pressoreceptors; Propranolol; Rats; Rats, Inbred SHR; Receptors, Opioid; Reflex; Splanchnic Nerves; Thiophenes; Yohimbine | 1985 |
[Antidepressant drugs and central monoaminergic receptors].
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Blood Platelets; Brain; Brain Chemistry; Cats; Clonidine; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Mianserin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Yohimbine | 1985 |
Heterogeneity of alpha-2 adrenergic receptors.
Topics: Animals; Blood Platelets; Brain; Cerebral Cortex; Clonidine; Corpus Striatum; Dogs; Guinea Pigs; Humans; Oxymetazoline; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Species Specificity; Submandibular Gland; Yohimbine | 1985 |
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors.
Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine | 1986 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
Pharmacology of centrally acting hypotensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methyldopa; Phenylacetates; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1980 |
Biochemical characteristics and regulation of brain alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Epinephrine; Humans; Hydroxydopamines; Hypertension; Methylazoxymethanol Acetate; Oxidopamine; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Species Specificity; Synapses; Tissue Distribution; Yohimbine | 1984 |
Mechanisms of hormonal regulations in brown adipose tissue of developing rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Animals, Newborn; Body Temperature Regulation; Clonidine; Cold Temperature; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Norepinephrine; Phosphoprotein Phosphatases; Protein Kinases; Rats; Receptors, Adrenergic; Yohimbine | 1984 |
Alpha-2 receptors in the gastrointestinal system: a new therapeutic approach.
Topics: Adrenergic alpha-Agonists; Animals; Antidiarrheals; Brain; Carbachol; Clonidine; Cysteamine; Deoxyglucose; Gastric Acid; Gastrins; Gastrointestinal Motility; Humans; Injections, Intraventricular; Norepinephrine; Peptic Ulcer; Phenylurea Compounds; Time Factors; Yohimbine | 1984 |
Alpha-adrenergic receptor subtypes.
Topics: Animals; Binding, Competitive; Clonidine; Dihydroergotoxine; Epinephrine; Heart Rate; Humans; Hypertension; In Vitro Techniques; Models, Biological; Norepinephrine; Phentolamine; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Effect of chronic treatment with tricyclic antidepressant drugs on identified brain noradrenergic and serotonergic neurons.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Clonidine; Drug Interactions; Imipramine; Iontophoresis; Lysergic Acid Diethylamide; Male; Neurons; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Yohimbine | 1980 |
Molecular mechanisms involved in alpha-adrenergic responses.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Calcium; Clonidine; Cyclic AMP; Epinephrine; Glucose; Guanosine Triphosphate; Liver; Nordefrin; Phenylephrine; Phosphatidylinositols; Phosphorylase a; Phosphorylase b; Prazosin; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1981 |
Drug effects on the EEG of various species of laboratory animals.
Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine | 1983 |
Yohimbine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antidotes; Clonidine; Humans; Poisoning; Yohimbine | 2000 |
31 trial(s) available for clonidine and yohimbine
| Article | Year |
|---|---|
Noradrenergic neuronal dysregulation in panic disorder: the effects of intravenous yohimbine and clonidine in panic disorder patients.
Topics: Adult; Arousal; Blood Pressure; Clonidine; Double-Blind Method; Female; Growth Hormone; Humans; Hydrocortisone; Infusions, Intravenous; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Panic Disorder; Personality Inventory; Receptors, Adrenergic; Yohimbine | 1992 |
Evidence that alpha 2-adrenergic pathways play a major role in growth hormone (GH) neuroregulation: alpha 2-adrenergic agonism counteracts the inhibitory effect of muscarinic cholinergic receptor blockade on the GH response to GH-releasing hormone, while
Topics: Adult; Atropine; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Homeostasis; Humans; Hypothalamus; Kinetics; Male; Pyridostigmine Bromide; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Somatostatin; Time Factors; Yohimbine | 1991 |
Effects of clonidine and yohimbine on the pupillary light reflex and carbachol-evoked sweating in healthy volunteers.
Topics: Adult; Affect; Blood Pressure; Carbachol; Clonidine; Double-Blind Method; Hemodynamics; Humans; Light; Male; Reflex, Pupillary; Sweating; Yohimbine | 1991 |
Alpha 2-adrenergic mechanism in menopausal hot flushes.
Topics: Adult; Climacteric; Clonidine; Female; Galvanic Skin Response; Humans; Hypothalamus; Middle Aged; Receptors, Adrenergic, alpha; Skin Temperature; Time Factors; Yohimbine | 1990 |
Effect of clonidine and yohimbine on sleep in man: polygraphic study and EEG analysis by normalized slope descriptors.
Topics: Adult; Brain; Clonidine; Electroencephalography; Humans; Sleep; Sleep, REM; Yohimbine | 1985 |
Alpha 2-adrenergic receptor sensitivity in depressed patients: relation between 3H-yohimbine binding to platelet membranes and clonidine-induced hypotension.
Topics: Adult; Blood Platelets; Blood Pressure; Cell Membrane; Clinical Trials as Topic; Clonidine; Depressive Disorder; Double-Blind Method; Female; Humans; Hypotension; Imipramine; Male; Middle Aged; Receptors, Adrenergic; Tyrosine; Yohimbine | 1989 |
The effects of clonidine and yohimbine on human information processing.
Topics: Adolescent; Adult; Clonidine; Emotions; Hemodynamics; Humans; Male; Mental Processes; Norepinephrine; Reaction Time; Yohimbine | 1989 |
Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder.
Topics: Adult; Agoraphobia; Anxiety Disorders; Blood Pressure; Clonidine; Fear; Female; Growth Hormone; Humans; Hydrocortisone; Male; Methoxyhydroxyphenylglycol; Panic; Placebos; Posture; Receptors, Adrenergic, alpha; Sleep; Sympathetic Nervous System; Yohimbine | 1986 |
Anxiogenic effect of yohimbine in healthy subjects: comparison with caffeine and antagonism by clonidine and diazepam.
Topics: Adult; Anxiety; Arousal; Caffeine; Clonidine; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Female; Growth Hormone; Humans; Hydrocortisone; Male; Panic; Prolactin; Yohimbine | 1988 |
Bupropion does not antagonize cardiovascular actions of clonidine in normal subjects and spontaneously hypertensive rats.
Topics: Adult; Animals; Blood Platelets; Blood Pressure; Bupropion; Clonidine; Desipramine; Heart Rate; Humans; Imipramine; In Vitro Techniques; Male; Propiophenones; Rats; Rats, Inbred Strains; Tritium; Yohimbine | 1984 |
Melatonin responses to clonidine and yohimbine challenges.
Topics: Adult; Arousal; Circadian Rhythm; Clonidine; Female; Humans; Melatonin; Reference Values; Yohimbine | 1995 |
Effects of Alzheimer's disease and normal aging on cerebrospinal fluid norepinephrine responses to yohimbine and clonidine.
Topics: Adult; Aged; Aging; Alzheimer Disease; Ambulatory Care; Analysis of Variance; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Male; Norepinephrine; Psychiatric Status Rating Scales; Stimulation, Chemical; Yohimbine | 1995 |
Partial reversal of the effects of extradural clonidine by oral yohimbine in postoperative patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesia, Epidural; Blood Pressure; Clonidine; Female; Heart; Humans; Male; Middle Aged; Pain, Postoperative; Time Factors; Yohimbine | 1993 |
Effects of physiological and pharmacological variation of sympathetic nervous system activity on plasma non-esterified fatty acid concentrations in man.
Topics: Adult; Blood Glucose; Catecholamines; Clonidine; Fatty Acids, Nonesterified; Humans; Male; Norepinephrine; Posture; Pressoreceptors; Reflex; Supine Position; Sympathetic Nervous System; Yohimbine | 1993 |
The effect of Yohimbine, an alpha2 adrenergic receptor antagonist, on the growth hormone response to apomorphine in normal subjects.
Topics: Adrenergic alpha-Antagonists; Adult; Apomorphine; Clonidine; Dopamine Agonists; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Placebos; Yohimbine | 1996 |
Effect of clonidine and yohimbine on sleep in healthy men: a double-blind, randomized, controlled trial.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Clonidine; Double-Blind Method; Humans; Male; Middle Aged; Sleep, REM; Yohimbine | 1996 |
Differential effects of noradrenergic drugs on anxiety and arousal in healthy volunteers with high and low anxiety.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Anxiety; Arousal; Clonidine; Cross-Over Studies; Double-Blind Method; Electroencephalography; Humans; Male; Mental Processes; Methoxyhydroxyphenylglycol; Norepinephrine; Psychiatric Status Rating Scales; Yohimbine | 1996 |
Adrenergic modulation of human colonic motor and sensory function.
Topics: Adrenergic Agents; Adult; Anxiety; Blood Pressure; Clonidine; Colon; Depression; Female; Gastrointestinal Motility; Heart Rate; Humans; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Phenylephrine; Postprandial Period; Pressure; Ritodrine; Sensation; Single-Blind Method; Stress, Psychological; Yohimbine | 1997 |
Alpha 2-adrenergic modulation of colonic tone during hyperventilation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Clonidine; Colon; Female; Gastrointestinal Motility; Heart Rate; Humans; Hyperventilation; Male; Muscle Tonus; Muscle, Smooth; Phenylephrine; Receptors, Adrenergic, alpha-2; Ritodrine; Yohimbine | 1997 |
Cerebrospinal fluid epinephrine in Alzheimer's disease and normal aging.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aging; Alzheimer Disease; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Male; Yohimbine | 1998 |
Yohimbine in neurally mediated syncope. Pathophysiological implications.
Topics: Adult; Clonidine; Epinephrine; Female; Hemodynamics; Humans; Male; Norepinephrine; Prospective Studies; Random Allocation; Sympathetic Nervous System; Syncope, Vasovagal; Tilt-Table Test; Yohimbine | 1998 |
Characteristics of norepinephrine and clonidine displacement of [3H]yohimbine binding to platelet alpha2-adrenoreceptors in healthy volunteers.
Topics: Adult; Binding Sites; Blood Platelets; Clonidine; Data Interpretation, Statistical; GTP-Binding Proteins; Humans; Male; Mental Disorders; Norepinephrine; Receptors, Adrenergic, alpha-2; Yohimbine | 1999 |
Increased plasma norepinephrine response to yohimbine in elderly men.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aging; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Humans; Male; Norepinephrine; Yohimbine | 2000 |
Comparison of the effects of clonidine and yohimbine on spontaneous pupillary fluctuations in healthy human volunteers.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Arousal; Blood Pressure; Clonidine; Humans; Male; Mydriatics; Pupil; Salivation; Yohimbine | 2000 |
Comparison of the effects of clonidine and yohimbine on pupillary diameter at different illumination levels.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Clonidine; Cross-Over Studies; Double-Blind Method; Humans; Iris; Light; Male; Peripheral Nervous System; Pupil; Receptors, Adrenergic, alpha-2; Reflex, Pupillary; Yohimbine | 2000 |
Alpha2-noradrenergic effects on ERP and behavioral indices of auditory information processing.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Auditory Perception; Clonidine; Double-Blind Method; Electroencephalography; Evoked Potentials; Humans; Male; Norepinephrine; Receptors, Adrenergic, alpha-2; Yohimbine | 2002 |
Clonidine and yohimbine in opioid-dependent humans responding under a naloxone novel-response discrimination procedure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Clonidine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Surveys and Questionnaires; Yohimbine | 2003 |
Heart rate and QT interval variability: abnormal alpha-2 adrenergic function in patients with panic disorder.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Long QT Syndrome; Male; Panic Disorder; Posture; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Influence of the noradrenergic system on the formation of intrusive memories in women: an experimental approach with a trauma film paradigm.
Topics: Adolescent; Adrenergic Agents; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Clonidine; Double-Blind Method; Female; Humans; Hydrocortisone; Memory, Episodic; Norepinephrine; Psychological Trauma; Yohimbine; Young Adult | 2016 |
Involvement of Opioid Receptors and α
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Blood Pressure; Central Nervous System Sensitization; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Administration Routes; Electric Stimulation; Female; Healthy Volunteers; Heart Rate; Humans; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Psychophysics; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine; Young Adult | 2016 |
Increased Sympathetic Outflow Induces Adaptation to Acute Experimental Pain.
Topics: Acute Pain; Adaptation, Physiological; Adult; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Male; Pain Perception; Pain Threshold; Single-Blind Method; Sympathetic Nervous System; Yohimbine; Young Adult | 2018 |
1235 other study(ies) available for clonidine and yohimbine
| Article | Year |
|---|---|
Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Imidazoles; Indoles; Male; Mice; Nociceptors; Pain; Prazosin; Quinolines; Rats; Structure-Activity Relationship; Vas Deferens | 1987 |
4-Amino-6-chloro-2-piperazinopyrimidines with selective affinity for alpha 2-adrenoceptors.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clonidine; Corpus Striatum; Dioxanes; Idazoxan; Piperazines; Pyrimidines; Rats; Receptors, Adrenergic, alpha; Spiperone; Structure-Activity Relationship | 1986 |
Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor.
Topics: Affinity Labels; Clonidine; Humans; Iodine Radioisotopes; Receptors, Adrenergic, alpha | 1987 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens | 1983 |
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction | 1984 |
Alpha-adrenoreceptor reagents. 2. Effects of modification of the 1,4-benzodioxan ring system on alpha-adrenoreceptor activity.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dioxins; Idazoxan; Indicators and Reagents; Male; Mice; Muscles; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Synapses; Vas Deferens | 1984 |
Synthesis and structure-activity relationships of N-propyl-N-(4-pyridinyl)-1H-indol-1-amine (besipirdine) and related analogs as potential therapeutic agents for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Biogenic Amines; Brain; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Parasympatholytics; Pyridines; Rats; Structure-Activity Relationship | 1996 |
Molecular basis of inverse agonism in a G protein-coupled receptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Cell Line; Fluorescence Resonance Energy Transfer; Humans; Ligands; Protein Binding; Receptors, Adrenergic, alpha-2; Receptors, G-Protein-Coupled; Signal Transduction | 2005 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Low Doses of Allyphenyline and Cyclomethyline, Effective against Morphine Dependence, Elicit an Antidepressant-like Effect.
Topics: | 2012 |
Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System; Clonidine; Dihydroxyphenylalanine; Dioxanes; Dopamine; Female; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Piperidines; Rats; Receptors, Adrenergic; Reflex; Spinal Cord; Tolazoline; Yohimbine | 1976 |
Noradrenaline synthesis and utilization: control by nerve impulse flow under normal conditions and after treatment with alpha-adrenoreceptor blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Brain; Clonidine; Denervation; Dihydroxyphenylalanine; Dioxanes; Dopamine; Haloperidol; Hydrazines; Male; Methyltyrosines; Norepinephrine; Normetanephrine; Phenoxybenzamine; Piperidines; Rats; Spinal Cord; Tolazoline; Tyramine; Yohimbine | 1976 |
Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Synapses; Vas Deferens; Yohimbine | 1977 |
Mianserin--an analysis of its peripheral autonomic actions.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Electric Stimulation; Male; Mianserin; Norepinephrine; Phenoxybenzamine; Phentolamine; Rats; Tyramine; Yohimbine | 1978 |
A comparative study on the pre- and post-synaptic alpha blocking activity of a series of benzodioxanes.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Piperidines; Piperoxan; Rats; Synapses; Yohimbine | 1978 |
Novel alpha2-adrenoreceptors primarily responsible for inducing human platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Humans; Phenylephrine; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Vasopressins; Yohimbine | 1979 |
Chronic effects of mianserin on noradrenaline metabolism in the rat brain: evidence for a pre-synaptic alpha-adrenolytic action in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain Chemistry; Clonidine; Dibenzazepines; Drug Interactions; Male; Mianserin; Norepinephrine; Normetanephrine; Rats; Synapses; Yohimbine | 1979 |
Noradrenergic agonists and antagonists: effects on conditioned fear as measured by the potentiated startle paradigm.
Topics: Animals; Clonidine; Conditioning, Operant; Fear; Male; Norepinephrine; Piperoxan; Propranolol; Rats; Reflex, Startle; Yohimbine | 1979 |
Clonidine antinociceptive activity: effects of drugs influencing central monoaminergic and cholinergic mechanisms in the rat.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Atropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Chlorpromazine; Clonidine; Electroshock; Fenclonine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Naloxone; Parasympathetic Nervous System; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Sympathetic Nervous System; Vocalization, Animal; Yohimbine | 1976 |
On the functional role of pre- and postsynaptic catecholamine receptors in brain.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dopamine; Hydroxylation; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Drug; Receptors, Neurotransmitter; Reserpine; Synapses; Tryptophan; Tyrosine; Yohimbine | 1975 |
Pharmacological evidence for a stimulation of dopamine neurons by noradrenaline neurons in the brain.
Topics: Animals; Brain; Brain Chemistry; Clonidine; Dopamine; In Vitro Techniques; Male; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Reserpine; Yohimbine | 1976 |
Regulation in the central norepinephrine neurotransmission induced in vivo by alpha adrenoceptor active drugs.
Topics: Animals; Brain; Butyrophenones; Clonidine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Transmission; Synaptosomes; Tyrosine; Yohimbine | 1976 |
The influence of alpha-receptors on lordosis in the female rat.
Topics: Animals; Castration; Clonidine; Drug Interactions; Female; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1977 |
Paradoxical sleep inhibition by central alpha-adrenoceptor stimulant clonidine antagonized by alpha-receptor blocker yohimbine.
Topics: Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Receptors, Adrenergic, alpha; Sleep; Sleep, REM; Yohimbine | 1977 |
Direct biochemical demonstration of two types of alpha-adrenoreceptor in rat brain.
Topics: Animals; Binding, Competitive; Brain; Clonidine; Dihydroergotoxine; Dopamine; Male; Phenoxybenzamine; Phentolamine; Piperoxan; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine | 1978 |
Prazosin and presynaptic alpha-receptors in the cardioaccelerator nerve of the dog.
Topics: Animals; Clonidine; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Male; Myocardial Contraction; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vagotomy; Yohimbine | 1978 |
alpha-Adrenergic modulation of hypothalamic self-stimulation: effects of phenoxybenzamine, yohimbine, dexamphetamine and their interactions with clonidine.
Topics: Animals; Clonidine; Dextroamphetamine; Drug Interactions; Electrodes, Implanted; Hypothalamus; Male; Methyltyrosines; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Self Stimulation; Yohimbine | 1978 |
An analysis of some factors influencing alpha-adrenoceptor feed-back at the sympathetic junction in the rat heart.
Topics: Adrenalectomy; Animals; Clonidine; Cocaine; Electric Stimulation; Feedback; Heart; Heart Rate; Male; Neuromuscular Junction; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1979 |
Prejunctional inhibitory alpha-adrenoceptors and dopaminoceptors of the rat vas deferens and the guinea-pig ileum in vitro.
Topics: Animals; Apomorphine; Clonidine; Dopamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Norepinephrine; Oxymetazoline; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Vas Deferens; Yohimbine | 1979 |
Inhibition of sympathetic transmission in rat heart by clonidine: the roles of stimulation frequency, endogenous feedback and noradrenaline re-uptake.
Topics: Animals; Clonidine; Cocaine; Electric Stimulation; Feedback; Heart; Heart Rate; Male; Myocardium; Norepinephrine; Rats; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 1979 |
[An analysis of the discrepancy between the effects of central and peripheral alpha-adrenoceptor stimulations (author's transl)].
Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hypotension; Picrotoxin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1979 |
Topical clonidine produces mydriasis by a central nervous system action.
Topics: Administration, Topical; Animals; Blood Pressure; Cats; Central Nervous System; Ciliary Body; Clonidine; Epinephrine; Female; Heart Rate; Iris; Male; Mydriatics; Parasympathetic Nervous System; Pupil; Sympathetic Nervous System; Yohimbine | 1979 |
Effect of clonidine on utilization and potassium-evoked release of adrenaline in rat brain areas.
Topics: Animals; Brain; Clonidine; Epinephrine; Hypothalamus; Male; Organ Specificity; Potassium; Prazosin; Rats; Yohimbine | 1979 |
Effects of pretreatment with 6-hydroxydopamine or noradrenergic receptor blockers on the clonidine-induced distruption of conditioned avoidance responding.
Topics: Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Hydroxydopamines; Male; Phentolamine; Propranolol; Rats; Sympatholytics; Yohimbine | 1979 |
Anticonvulsant effect of yohimbine in quaking mice: antagonism by clonidine and prazosine.
Topics: Animals; Anticonvulsants; Clonidine; Male; Mice; Mice, Quaking; Phentolamine; Prazosin; Quinazolines; Seizures; Yohimbine | 1979 |
Effects of clonidine and chlorpromazine on a sympathetic-cholinergic reflex.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Clonidine; Galvanic Skin Response; Parasympathetic Nervous System; Reflex; Sympathetic Nervous System; Yohimbine | 1979 |
Clonidine mydriasis in the cat. Further evidence for a CNS postsynaptic action.
Topics: Animals; Biogenic Amines; Cats; Central Nervous System; Clonidine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Hexamethonium Compounds; Male; Methyltyrosines; Mydriatics; Pupil; Synapses; Yohimbine | 1979 |
Modification by antihypertensive drugs of amphetamine-induced stereotypy in rats.
Topics: Animals; Antihypertensive Agents; Behavior; Clonidine; Dextroamphetamine; Drug Interactions; Humans; Male; Mianserin; Prazosin; Rats; Stereotyped Behavior; Yohimbine | 1979 |
Effect of clonidine on sleep patterns in man.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Male; Sleep; Sleep Stages; Yohimbine | 1977 |
Effect of pre-synaptic alpha-adrenoceptor blockade on the chronotropic response to cardiac sympathetic nerve stimulation in the pithed rat [proceedings].
Topics: Animals; Clonidine; Heart; Heart Rate; Rats; Sympathetic Nervous System; Yohimbine | 1977 |
Effect of clonidine and chlorpromazine on centrally evoked electrodermal responses and their interaction with yohimbine.
Topics: Animals; Cats; Chlorpromazine; Clonidine; Drug Interactions; Electric Stimulation; Galvanic Skin Response; Hypothalamus; Time Factors; Yohimbine | 1977 |
Evidence for involvement of central noradrenergic neurons in the cardiovascular depression induced by morphine in the rat.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Brain; Cardiovascular System; Clonidine; Heart Rate; Male; Morphine; Naloxone; Norepinephrine; Protriptyline; Rats; Reflex; Yohimbine | 1976 |
A benzodioxanhydroxyethylpiperidine derivative with an acute central hypotensive action, different from that of clonidine. A comparison with neuroleptic agents.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cats; Clonidine; Dioxanes; Drug Interactions; Female; Male; Piperidines; Stellate Ganglion; Stereoisomerism; Sympathectomy; Time Factors; Tranquilizing Agents; Vagotomy; Yohimbine | 1975 |
The electrodermal response as a model for central sympathetic reactivity: the action of clonidine.
Topics: Animals; Blood Pressure; Cats; Clonidine; Electric Stimulation; Female; Galvanic Skin Response; Heart Rate; Hypothalamus; Male; Models, Neurological; Peripheral Nerves; Sympathetic Nervous System; Yohimbine | 1976 |
[Modulation of 3,4-diaminopyridine-evoked norepinephrine release from rat hippocampal slices by activation of alpha 2-adrenoceptor].
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium Channel Blockers; Clonidine; Hippocampus; In Vitro Techniques; Male; Norepinephrine; omega-Conotoxin GVIA; Peptides, Cyclic; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Ruthenium Red; Yohimbine | 1992 |
Effect of clonidine on experimental brain edema in the rat.
Topics: Animals; Blood Pressure; Brain; Brain Edema; Clonidine; Copper; Dexamethasone; Indomethacin; Male; Phospholipases A; Phospholipases A2; Potassium; Rats; Rats, Wistar; Sodium; Yohimbine | 1992 |
Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon.
Topics: Adenylate Cyclase Toxin; Animals; Binding, Competitive; Cell Membrane; Clonidine; Colforsin; Colon; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 1992 |
Preoptic norepinephrine-induced hypothermia is mediated by alpha 2-adrenoceptors.
Topics: Animals; Atenolol; Body Temperature; Body Temperature Regulation; Clonidine; Dialysis; Dobutamine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Norepinephrine; Practolol; Preoptic Area; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Skin Temperature; Yohimbine | 1992 |
Characterization of alpha 2-adrenergic receptors on rat pinealocytes.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Iodine Radioisotopes; Kinetics; Male; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1992 |
Functional characterization of alpha-adrenoceptors on pancreatic islets of fa/fa Zucker rats.
Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Glucose; Insulin; Islets of Langerhans; Obesity; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Isolated failure of noradrenergic transmission in a case with orthostatic hypotension and hyperactivity of gastro-colic reflex.
Topics: Adult; Atropine; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Colon; Defecation; Edrophonium; Epinephrine; Heart Rate; Humans; Hypotension, Orthostatic; Male; Norepinephrine; Reference Values; Stomach; Synaptic Transmission; Tyramine; Valsalva Maneuver; Yohimbine | 1992 |
L-dopa is protective against indomethacin-induced small intestinal ulceration in the rat: possible role of an alpha-2-adrenergic mechanism.
Topics: Animals; Clonidine; Haloperidol; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Ulcer; Yohimbine | 1992 |
The contribution of alpha-adrenoceptors to neurally-mediated contractions of the rabbit urethral smooth muscle.
Topics: Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Urethra; Yohimbine | 1992 |
Expression of Fos-like immunoreactivity by yohimbine and clonidine in the rat brain.
Topics: Animals; Brain; Clonidine; Genes, fos; Guanabenz; Immunoenzyme Techniques; Immunohistochemistry; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Overexpression of alpha 2-adrenergic receptors in fetal rat heart: receptors in search of a function.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Clonidine; Colforsin; Fetal Heart; Gestational Age; In Vitro Techniques; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Effects of imidazole compounds on catecholamine release in adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Clonidine; Guanabenz; Imidazoles; Phenoxybenzamine; Receptors, Adrenergic, alpha; Tolazoline; Yohimbine | 1992 |
Central alpha 2-adrenoceptor-mediated pressor response to clonidine in conscious, spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Furosemide; Heart Rate; Hypertension; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Water Deprivation; Yohimbine | 1992 |
Different types of norepinephrinergic receptors are involved in preoptic area mediated independent modulation of sleep-wakefulness and body temperature.
Topics: Acetamides; Animals; Body Temperature Regulation; Clonidine; Isoproterenol; Male; Methoxamine; Prazosin; Preoptic Area; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic; Sleep; Sodium Chloride; Wakefulness; Yohimbine | 1992 |
Pancreastatin increases cytosolic Ca2+ in insulin secreting RINm5F cells.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cell Line; Chromogranin A; Clonidine; Cytosol; Flow Cytometry; Insulin; Insulin Secretion; Pancreatic Hormones; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Activation of 5-HT2 receptors inhibits the evoked release of [3H]noradrenaline in the rat spinal cord.
Topics: Amphetamines; Animals; Clonidine; Electric Stimulation; Female; Hallucinogens; In Vitro Techniques; Ketanserin; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Serotonin Receptor Agonists; Spinal Cord; Yohimbine | 1992 |
Involvement of alpha 2-adrenoceptors in the sacral micturition reflex in rats.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Injections, Spinal; Male; Neurons; Phenylephrine; Pons; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Reflex; Urinary Bladder; Yohimbine | 1992 |
A simple biochemical approach to differentiate synaptosomes and non-synaptic mitochondria from rat brain.
Topics: Animals; Brain; Cell Fractionation; Centrifugation, Density Gradient; Clonidine; In Vitro Techniques; Isoproterenol; Mitochondria; Propranolol; Rats; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Yohimbine | 1992 |
Release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.
Topics: Animals; Butoxamine; Calcium; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Ganglionic Blockers; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Metoprolol; Norepinephrine; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Splanchnic Nerves; Stomach; Tetrodotoxin; Yohimbine | 1992 |
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible receptor inactivator, as a tool for measurement of alpha 2-adrenoceptor occupancy in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Male; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Alpha-adrenergic input in the locus coeruleus modulates plasma adrenocorticotropin in cats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Cats; Clonidine; Female; Glutamates; Glutamic Acid; Kinetics; Locus Coeruleus; Male; Microinjections; Phenylephrine; Pons; Prazosin; Radioimmunoassay; Receptors, Adrenergic, alpha; Reference Values; Time Factors; Yohimbine | 1992 |
Differential localization of alpha 2-adrenergic receptor subtypes in brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain Chemistry; Clonidine; Dioxanes; Guanylyl Imidodiphosphate; Idazoxan; Male; Perfusion; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1992 |
Effects of opioid and alpha 2-adrenoceptor agonists on the isolated ileum of morphine-dependent guinea-pigs during withdrawal and after clonidine treatment.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Drug Tolerance; Electric Stimulation; Guinea Pigs; Ileum; Male; Morphine; Morphine Dependence; Myenteric Plexus; Naloxone; Narcotics; Neuromuscular Junction; Substance Withdrawal Syndrome; Yohimbine | 1992 |
Immunoprecipitation of alpha 2a-adrenergic receptor-GTP-binding protein complexes using GTP-binding protein selective antisera. Changes in receptor/GTP-binding protein interaction following agonist binding.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Line; Clonidine; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immune Sera; Iodine Radioisotopes; Precipitin Tests; Quinoxalines; Receptors, Adrenergic, alpha; Swine; Yohimbine | 1992 |
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
Effects of alpha-adrenoceptor antagonists and clonidine on the haemodynamic response to acute hypovolaemia in conscious rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemorrhage; Injections, Intravenous; Pharmaceutical Vehicles; Plasma Volume; Quinazolines; Rabbits; Yohimbine | 1992 |
Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Clonidine; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Nerve Endings; Neurotransmitter Agents; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1992 |
Evidence for noradrenergic involvement in mediating the FG 7142 discriminative stimulus.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Carbolines; Clonidine; Dioxanes; Discrimination, Psychological; Electroshock; Generalization, Stimulus; Idazoxan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Stress, Psychological; Yohimbine | 1992 |
Yohimbine-precipitated clonidine withdrawal: an experimental model of the antihypertensive drug withdrawal syndrome.
Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Central Nervous System; Choline; Clonidine; Ganglia, Sympathetic; Ganglionic Blockers; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Injections, Intraventricular; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Yohimbine | 1992 |
Further studies on the anti-nociceptive effect of vasopressin.
Topics: Analgesics; Animals; Arginine Vasopressin; Clonidine; Male; Mice; Naloxone; Yohimbine | 1992 |
Chronic clonidine treatment and its termination: effects on penile erection and ejaculation in the dog.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Ejaculation; Imidazoles; Male; Naloxone; Penile Erection; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1992 |
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat.
Topics: Adrenergic beta-Antagonists; Analgesics; Analysis of Variance; Animals; Arthritis, Experimental; Clonidine; Dioxanes; Idazoxan; Injections, Intravenous; Male; Pain; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Vocalization, Animal; Yohimbine | 1992 |
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation?
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine | 1992 |
The effects of (+/-)-idazoxan and its stereoisomers on mouse vas deferens motility in vitro. A comparison with yohimbine.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Male; Mice; Norepinephrine; Stereoisomerism; Vas Deferens; Yohimbine | 1992 |
[Effects of four adrenergic drugs on electroacupuncture analgesia].
Topics: Acupuncture Analgesia; Adrenergic alpha-Agonists; Animals; Clonidine; Electroacupuncture; Female; Methoxamine; Pain Threshold; Prazosin; Rats; Yohimbine | 1992 |
Local application of drugs to sympathetic nerve terminals: an electrophysiological analysis of the role of prejunctional alpha-adrenoceptors in the guinea-pig vas deferens.
Topics: Adenosine Triphosphate; Animals; Clonidine; Guinea Pigs; In Vitro Techniques; Male; Neurotransmitter Agents; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Tyramine; Vas Deferens; Yohimbine | 1991 |
Spinal 5-HT pathways and the antinociception induced by intramedullary clonidine in rats.
Topics: 5,7-Dihydroxytryptamine; Analgesics; Animals; Clonidine; Cyproheptadine; Injections, Spinal; Male; Medulla Oblongata; Microinjections; Neural Pathways; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Yohimbine | 1992 |
Effects of clonidine on the calcium content and morphology of rat salivary glands.
Topics: Animals; Calcium; Clonidine; Cytoplasmic Granules; Dopamine; Male; Norepinephrine; Parotid Gland; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Salivary Glands; Sublingual Gland; Submandibular Gland; Yohimbine | 1992 |
Yohimbine attenuates clonidine-induced feeding and macronutrient selection in genetically obese (ob/ob) mice.
Topics: Animals; Clonidine; Diet; Dietary Carbohydrates; Energy Intake; Feeding Behavior; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Yohimbine | 1992 |
Atypical presynaptic alpha-adrenoceptor modulation of neurally-mediated cholinergic responses in guinea-pig tracheal smooth muscle.
Topics: Animals; Clonidine; Drug Interactions; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Trachea; Yohimbine | 1992 |
Interactions between the effects of endothelin-1, clonidine and yohimbine on electrically-induced contractions in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Clonidine; Electric Stimulation; Endothelins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1992 |
Production and characterization of an iminoimidazolidine specific monoclonal antibody using para-aminoclonidine as antigen.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Antigens; Binding, Competitive; Brain; Clonidine; Female; Glutaral; Hemocyanins; Humans; Imidazoles; Kinetics; Mice; Mice, Inbred BALB C; Prazosin; Tissue Extracts; Vaccines, Synthetic; Yohimbine | 1992 |
Clonidine and yohimbine modulate the effects of naloxone on novelty-induced hypoalgesia.
Topics: Animals; Clonidine; Environment; Male; Naloxone; Pain; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1992 |
[Inhibitory effect of clonidine on hemolysis after thermal injury in animals].
Topics: Animals; Burns; Clonidine; Glutathione; Glutathione Peroxidase; Hemolysis; Male; Mice; Norepinephrine; Osmotic Fragility; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1992 |
alpha N-acetyl human beta-endorphin-(1-31) alleviates the morphine withdrawal syndrome in rodents: a comparative study with clonidine.
Topics: Animals; beta-Endorphin; Clonidine; Disease Models, Animal; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine | 1992 |
Two peptides from the alpha 2A-adrenergic receptor alter receptor G protein coupling by distinct mechanisms.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blood Platelets; Cell Line; Cell Membrane; Clonidine; Glioma; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Kinetics; Molecular Sequence Data; Neuroblastoma; Peptides; Protein Conformation; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Alpha 1- and alpha 2-adrenergic response in human isolated skin arteries during cooling.
Topics: Adult; Aged; Arteries; Clonidine; Cold Temperature; Drug Interactions; Humans; In Vitro Techniques; Isometric Contraction; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Phenylephrine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Regional Blood Flow; Skin; Yohimbine | 1991 |
Interaction of berberine with human platelet alpha 2 adrenoceptors.
Topics: Adult; Alprostadil; Berberine; Blood Platelets; Clonidine; Cyclic AMP; Epinephrine; Humans; Norepinephrine; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Suppression of copulatory behavior in male rats following central administration of clonidine.
Topics: Animals; Clonidine; Copulation; Hypothalamus; Injections; Injections, Intraventricular; Male; Preoptic Area; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Alpha 1-adrenergic receptor coupling with phospholipase-C is negatively regulated by protein kinase-C in primary cultures of hypothalamic neurons and glial cells.
Topics: Animals; Astrocytes; Calcium Channels; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Clonidine; Diglycerides; Feedback; GTP-Binding Proteins; Hypothalamus; Inositol Phosphates; Kinetics; Membrane Lipids; Mice; Neurons; Norepinephrine; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Propranolol; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Type C Phospholipases; Yohimbine | 1991 |
Termination of digitalis-induced ventricular tachycardias by clonidine involves central alpha 2-adrenoceptors in cats.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cats; Clonidine; Digitalis Glycosides; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Male; Receptors, Adrenergic, alpha; Strophanthidin; Tachycardia; Yohimbine | 1991 |
Active alpha 2 and beta adrenoceptors in lymphocytes from patients with chronic lymphocytic leukemia.
Topics: Aged; Aged, 80 and over; Clonidine; Cyclic AMP; Female; Humans; Isoproterenol; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Middle Aged; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Temperature; Yohimbine | 1991 |
The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (-)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Ganglia, Sympathetic; Heart Rate; Kidney; Maprotiline; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Stereoisomerism; Sympathetic Nervous System; Yohimbine | 1991 |
Release of contractile agents from rat vas deferens by clonidine.
Topics: Animals; Clonidine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Uterus; Vas Deferens; Yohimbine | 1991 |
Studies on the interaction between presynaptic alpha 2-adrenoceptors and adenosine A1 receptors located on noradrenergic nerve terminals.
Topics: Animals; Clonidine; Electric Stimulation; Female; Hippocampus; In Vitro Techniques; Male; Nerve Endings; Norepinephrine; Phenylisopropyladenosine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Purinergic; Xanthines; Yohimbine | 1991 |
Interrelation between alpha 2-adrenoreceptor system and neuropeptide Y in rat nucleus tractus solitarii.
Topics: Animals; Blood Pressure; Clonidine; Dioxanes; Heart Rate; Idazoxan; Immunization, Passive; Kinetics; Male; Medulla Oblongata; Neuropeptide Y; Nordefrin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Alprostadil; Animals; Blood Platelets; Clonidine; Colforsin; Down-Regulation; Humans; Male; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Statistics as Topic; Yohimbine | 1991 |
[Neuropeptide Y, orthosympathetic nervous system, hypertension and alpha-2 adrenergic receptors].
Topics: Animals; Clinical Protocols; Clonidine; Dogs; Hypertension; Neuropeptide Y; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1991 |
Central alpha-2 adrenergic mechanisms in the renal nerve mediated natriuresis and diuresis produced by acute volume expansion.
Topics: Animals; Blood Pressure; Brain; Clonidine; Denervation; Diuresis; Isotonic Solutions; Kidney; Male; Natriuresis; Nervous System Physiological Phenomena; Plasma Substitutes; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Chloride; Yohimbine | 1991 |
A role for central postsynaptic alpha 2-adrenoceptors in glucoregulation.
Topics: Animals; Blood Glucose; Brain; Clonidine; Gas Chromatography-Mass Spectrometry; Guanethidine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1991 |
Participation of an alpha 2-mediated mechanism in the production of forced swimming-stress induced analgesia in mice.
Topics: Analgesia; Animals; Clonidine; Drug Tolerance; Male; Mice; Naloxone; Physical Exertion; Receptors, Adrenergic, alpha; Stress, Physiological; Swimming; Yohimbine | 1991 |
Yohimbine can induce ethanol tolerance in an in vitro preparation of rat locus coeruleus.
Topics: Animals; Clonidine; Culture Techniques; Drug Tolerance; Ethanol; Locus Coeruleus; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1991 |
Tizanidine-induced depression of polysynaptic cutaneous reflexes in nonanesthetized monkeys is mediated by an alpha 2-adrenergic mechanism.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Electromyography; Macaca; Receptors, Adrenergic, alpha; Reflex; Skin; Synapses; Yohimbine | 1991 |
Bronchial effects of alpha 2-adrenoceptor antagonists in asthma.
Topics: Adrenergic alpha-Antagonists; Animals; Asthma; Clonidine; Dogs; Humans; Imidazoles; Yohimbine | 1991 |
An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain Stem; Clonidine; Dioxanes; Heart Rate; Idazoxan; Locus Coeruleus; Male; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Norepinephrine release during autoregulatory escape: effects of alpha 2-receptor blockade.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Homeostasis; Intestinal Mucosa; Intestines; Male; Norepinephrine; Phenylephrine; Regional Blood Flow; Sympathetic Nervous System; Yohimbine | 1991 |
Role of ventrolateral medulla in sympatholytic effect of 8-OHDPAT in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Lumbosacral Region; Male; Medulla Oblongata; Neurons; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Sympatholytics; Tetrahydronaphthalenes; Yohimbine | 1991 |
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine | 1991 |
Comparative study of postsynaptic alpha-adrenoceptors in aorta obtained from human and other mammalian species.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Clonidine; Guinea Pigs; Humans; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1991 |
Alpha 2-adrenergic modulation of glucagon and insulin secretions in sheep.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Clonidine; Dose-Response Relationship, Drug; Glucagon; Imidazoles; Insulin; Male; Pancreas; Radioimmunoassay; Receptors, Adrenergic, alpha; Sheep; Yohimbine | 1991 |
Potentiation of poststartle activity by conditioned fear: effects of anxiolytic and anxiogenic drugs.
Topics: Animals; Anti-Anxiety Agents; Arousal; Buspirone; Clonidine; Conditioning, Classical; Diazepam; Dose-Response Relationship, Drug; Fear; Male; Rats; Rats, Inbred Strains; Reflex, Startle; Xylazine; Yohimbine | 1991 |
Binding of [3H]-p-aminoclonidine to alpha 2-adrenoceptor states plus a non-adrenergic site on human platelet plasma membranes.
Topics: Adrenergic alpha-Agonists; Binding Sites; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Epinephrine; Humans; Norepinephrine; Radioligand Assay; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1991 |
Reevaluation of the role of alpha 2-adrenoreceptors in morphine-stimulated release of growth hormone.
Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Growth Hormone; Male; Morphine; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Testosterone; Yohimbine | 1991 |
Alpha 2-adrenoceptors not imidazole receptors mediate depression of a sacral spinal reflex in the cat.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cats; Clonidine; Female; Guanabenz; Imidazoline Receptors; Male; Receptors, Adrenergic, alpha; Receptors, Drug; Reflex; Spinal Cord; Yohimbine | 1991 |
Iontophoretic analysis of the pharmacologic mechanisms responsible for initiation and modulation of trigeminal motoneuronal discharge evoked by intra-oral afferent stimulation.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Clonidine; Dental Pulp; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Motor Neurons; Mouth Mucosa; Neck Muscles; Nerve Fibers; Norepinephrine; Phenylephrine; Prazosin; Synapses; Synaptic Transmission; Tongue; Trigeminal Nerve; Yohimbine | 1991 |
Alpha 2-adrenoceptor activation inhibits noradrenaline release in human and rabbit isolated renal arteries.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Animals; Brimonidine Tartrate; Clonidine; Female; Humans; In Vitro Techniques; Kidney; Male; Middle Aged; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renal Artery; Sympathetic Nervous System; Tetrodotoxin; Yohimbine | 1991 |
Adrenoceptors of the human internal thoracic artery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Clonidine; Dinoprostone; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic; Serotonin; Thoracic Arteries; Yohimbine | 1991 |
Influence of fenoldopam and quinpirole in the guinea-pig stomach.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clonidine; Dopamine; Dopamine Agents; Electric Stimulation; Ergolines; Female; Fenoldopam; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Methysergide; Muscle Contraction; Muscle Relaxation; Prazosin; Quinpirole; Stomach; Yohimbine | 1991 |
Effects of B-HT 920 in the tail-suspension test.
Topics: Adrenergic alpha-Agonists; Animals; Apomorphine; Azepines; Clonidine; Depressive Disorder; Dopamine Agents; Imipramine; Male; Mice; Motor Activity; Yohimbine | 1991 |
Effects of selective adrenergic agonists and antagonists on gastric tone in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Clonidine; Dose-Response Relationship, Drug; Phenylephrine; Prazosin; Prenalterol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stomach; Yohimbine | 1991 |
Dual action of clonidine on ethanol-induced gastric lesions: is the imidazoline-preferring receptor involved?
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Ethanol; Guanabenz; Imidazoline Receptors; Male; Methyldopa; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Stomach; Yohimbine | 1991 |
Sympatholytic action of yohimbine mediated by 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Heart Rate; Injections, Intravenous; Receptors, Serotonin; Spiperone; Sympathetic Nervous System; Tetrahydronaphthalenes; Yohimbine | 1991 |
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Heart Rate; Idazoxan; Phentolamine; Phenylephrine; Pyridazines; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Human plasma-derived material with clonidine displacing substance (CDS)-like properties contracts the isolated rat aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood; Brain; Clonidine; Dioxanes; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Prazosin; Rats; Rats, Inbred WKY; Yohimbine | 1991 |
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine | 1991 |
Contribution of alpha 2-adrenoceptors to the central cardiovascular effects of clonidine and S 8350 in anaesthetized rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Cardiovascular System; Cerebral Cortex; Clonidine; Heart Rate; Male; Oxazoles; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Catecholamines; Clonidine; Dioxanes; Electrochemistry; Hemodynamics; Idazoxan; Imidazoline Receptors; Male; Medulla Oblongata; Neurons; Oxazoles; Piperoxan; Rats; Rats, Inbred WKY; Receptors, Drug; Reticular Formation; Rilmenidine; Stereotaxic Techniques; Yohimbine | 1991 |
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine | 1990 |
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine | 1990 |
Enhanced contractile responses of arteries from diabetic rats to alpha 1-adrenoceptor stimulation in the absence and presence of extracellular calcium.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arteries; Calcium; Clonidine; Diabetes Mellitus, Experimental; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Characterization of extracellular histamine in the striatum and bed nucleus of the stria terminalis of the rat: an in vivo microdialysis study.
Topics: Animals; Clonidine; Corpus Striatum; Dialysis; Extracellular Space; Histamine; Histamine Release; Male; Methylhistidines; Rats; Rats, Inbred Strains; Tetrodotoxin; Thalamic Nuclei; Yohimbine | 1991 |
Naloxone-induced cardiovascular depression in rats that had received chronic morphine-treatment.
Topics: Anesthesia; Animals; Arteries; Atropine; Blood Pressure; Cardiac Complexes, Premature; Clonidine; Heart; Hemodynamics; In Vitro Techniques; Male; Morphine; Muscle, Smooth, Vascular; Naloxone; Rats; Rats, Inbred Strains; Tail; Yohimbine | 1991 |
Differential presynaptic effects of hexachlorocyclohexane isomers on noradrenaline release in cerebral cortex.
Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Hexachlorocyclohexane; In Vitro Techniques; Isomerism; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Statistics as Topic; Yohimbine | 1991 |
Influence of catecholamines on the in vivo release of histamine in the hypothalamus.
Topics: Animals; Catecholamines; Clonidine; Histamine Antagonists; Histamine Release; Hypothalamus; Kinetics; Male; Methylhistidines; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Inhibitory effects of clonidine and tizanidine on release of substance P from slices of rat spinal cord and antagonism by alpha-adrenergic receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Parasympatholytics; Piperoxan; Prazosin; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Veratridine; Yohimbine | 1991 |
In vivo modulation of the histamine release in the hypothalamus by adrenoreceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Histamine Release; Hypothalamus; Idazoxan; Male; Norepinephrine; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Clonidine differentially modulates the release of endogenous GABA in various rat brain areas.
Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; In Vitro Techniques; Male; Medulla Oblongata; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1991 |
Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Clonidine; Dose-Response Relationship, Drug; Hippocampus; Male; Neurons; Norepinephrine; Propylene Glycol; Propylene Glycols; Pyramidal Tracts; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Yohimbine | 1991 |
Naloxone-induced hypoalgesia: effects of noradrenergic antagonists and agonist.
Topics: Animals; Clonidine; Hot Temperature; Male; Naloxone; Norepinephrine; Pain; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds; Yohimbine | 1991 |
Clonidine inhibition of potassium-evoked release of glutamate and aspartate from rat cortical synaptosomes.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cerebral Cortex; Clonidine; Dioxanes; gamma-Aminobutyric Acid; Glutamates; Idazoxan; Kinetics; Male; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1991 |
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat.
Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Interaction between alpha 2- and beta-adrenergic receptors in rat cerebral cortical membranes: clonidine-induced reduction in agonist and antagonist affinity for beta-adrenergic receptors.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clonidine; Dihydroalprenolol; Guanosine Triphosphate; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathomimetics; Yohimbine | 1991 |
Interaction between the inhibitory effects of morphine and clonidine on intestinal transit in mice.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Female; Gastrointestinal Transit; Intestines; Mice; Mice, Inbred ICR; Morphine; Naloxone; Time Factors; Yohimbine | 1991 |
Regional differences in triglyceride breakdown in human adipose tissue: effects of catecholamines, insulin, and prostaglandin E2.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Buttocks; Clonidine; Dinoprostone; Epinephrine; Female; Humans; Insulin; Lipolysis; Male; Sex Characteristics; Triglycerides; Yohimbine | 1991 |
Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells.
Topics: Animals; Clonidine; Epinephrine; Glucose; Glyburide; Islets of Langerhans; Membrane Potentials; Mice; Potassium Channels; Tolbutamide; Yohimbine | 1991 |
Desipramine enhances isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; Clonidine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Prazosin; Social Isolation; Yohimbine | 1991 |
Intrathecal coadministration of clonidine with serotonin receptor agonists produces supra-additive visceral antinociception in the rat.
Topics: Amphetamines; Analgesics; Animals; Biogenic Monoamines; Clonidine; Dose-Response Relationship, Drug; Indoles; Injections, Spinal; Male; Methysergide; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Yohimbine | 1991 |
Imidazole binding sites in rabbit kidney and forebrain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Clonidine; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Norepinephrine; Parasympathetic Nervous System; Rabbits; Sympathetic Nervous System; Yohimbine | 1991 |
Physiological role of alpha-adrenoceptors in salivary secretion.
Topics: Animals; Autonomic Nervous System; Clonidine; Dose-Response Relationship, Drug; Female; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Submandibular Gland; Yohimbine | 1990 |
Effects of dilevalol on adrenoceptors in isolated cat arteries.
Topics: Animals; Arteries; Cats; Clonidine; Dinoprost; Electric Stimulation; Female; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction; Yohimbine | 1990 |
The effect of clonidine and related substances on voluntary ethanol consumption in rats.
Topics: Adrenergic alpha-Agonists; Alcohol Drinking; Animals; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Eating; Guanfacine; Guanidines; Phenylacetates; Rats; Rats, Inbred Strains; Thiophenes; Yohimbine | 1990 |
Concomitant depression of locus coeruleus neurons and of flexor reflexes by an alpha 2-adrenergic agonist in rats: a possible mechanism for an alpha 2-mediated muscle relaxation.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Locus Coeruleus; Male; Muscle Contraction; Muscle Relaxation; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Blood Vessels; Clonidine; Dioxanes; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1990 |
Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Idazoxan; Male; Pain; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Effects of neurotropic agents with a selectivity for alpha-adrenoceptors on nitrile-induced dyskinetic syndrome in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dyskinesia, Drug-Induced; Male; Mice; Nitriles; Phenylephrine; Prazosin; Yohimbine | 1990 |
Effects of alpha- and beta-adrenergic agonists and antagonists on growth hormone secretion in man.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; Clonidine; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Methoxamine; Phentolamine; Yohimbine | 1990 |
Pharmacological characterization of the postjunctional alpha-adrenoceptors of the rat isolated seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Naphazoline; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seminal Vesicles; Yohimbine | 1990 |
Adrenoceptor-activation of oxygen consumption in rat parotid acini.
Topics: Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Isoproterenol; Male; Microbial Collagenase; Oxygen Consumption; Parotid Gland; Pertussis Toxin; Phenylephrine; Rats; Receptors, Adrenergic; Virulence Factors, Bordetella; Yohimbine | 1990 |
Clonidine inhibits fluid absorption in the rabbit proximal convoluted renal tubule.
Topics: Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Clonidine; Female; Kidney Tubules, Proximal; Pertussis Toxin; Rabbits; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Water-Electrolyte Balance; Yohimbine | 1990 |
p-[125I]iodoclonidine is a partial agonist at the alpha 2-adrenergic receptor.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Blood Platelets; Cell Membrane; Chromatography, Thin Layer; Clonidine; GTP-Binding Proteins; Humans; Iodine Radioisotopes; Kinetics; Platelet Aggregation; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Comparison of 3H-para-aminoclonidine binding to different platelet preparations.
Topics: Adrenergic alpha-Agonists; Blood Platelets; Cell Membrane; Clonidine; Humans; Tritium; Yohimbine | 1990 |
Inhibitory effects of catecholamines in the paravertebral sympathetic ganglia of the anesthetized dog.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Catecholamines; Clonidine; Dogs; Ganglia, Sympathetic; Hexamethonium Compounds; Male; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Regional Blood Flow; Vascular Resistance; Yohimbine | 1990 |
Effects of alpha-adrenergic agents on generation of oscillatory afterpotentials and triggered activity in rabbit Purkinje fibers.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Male; Membrane Potentials; Phenylephrine; Potassium; Prazosin; Propranolol; Purkinje Fibers; Rabbits; Receptors, Adrenergic, alpha; Strophanthidin; Yohimbine | 1990 |
Alpha 1-adrenergic receptors in the brain: characterization in astrocytic glial cultures and comparison with neuronal cultures.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Astrocytes; Binding, Competitive; Brain; Cells, Cultured; Clonidine; Kinetics; Neurons; Norepinephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Alpha-2 adrenergic activity of bromocriptine and quinpirole in chicken pineal gland. Effects on melatonin synthesis and [3H]rauwolscine binding.
Topics: Animals; Arylamine N-Acetyltransferase; Binding Sites; Bromocriptine; Chickens; Clonidine; Dopamine Agents; Ergolines; Male; Melatonin; Membranes; Pineal Gland; Quinpirole; Receptors, Adrenergic, alpha; Retina; Tritium; Yohimbine | 1990 |
Differential alpha-1 and alpha-2 adrenergic effects on hypothalamic corticotropin-releasing factor and plasma adrenocorticotropin.
Topics: Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Animals; Anisomycin; Clonidine; Corticotropin-Releasing Hormone; Hypothalamus; Male; Methoxamine; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1990 |
Regulation of noradrenaline release in human cerebral arteries via presynaptic alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Azepines; Cerebral Arteries; Clonidine; Electric Stimulation; Humans; Methoxamine; Norepinephrine; Receptors, Adrenergic, alpha; Time Factors; Tritium; Yohimbine | 1990 |
Two distinct alpha 1-adrenoceptor subtypes involved in noradrenaline contraction of the rabbit thoracic aorta.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Female; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 1990 |
Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.
Topics: Amino Acids; Animals; Aspartic Acid; Clonidine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypertension; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synapses; Synaptic Transmission; Synaptosomes; Yohimbine | 1990 |
Isolated bovine cerebral arteries from rostral and caudal regions: distinct responses to adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Basilar Artery; Carotid Arteries; Cattle; Cerebral Arteries; Clonidine; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Yohimbine | 1990 |
Effect of alpha2 antagonists and an agonist on EEG slowing induced by scopolamine and lesion of the nucleus basalis.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Clonidine; Electroencephalography; Imidazoles; Norepinephrine; Occipital Lobe; Olivary Nucleus; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Yohimbine | 1990 |
Alpha 2-adrenergic stimulation within the nucleus tractus solitarius attenuates vasopressin release induced by depletion of cardiovascular volume.
Topics: Adrenergic alpha-Agonists; Animals; Arginine Vasopressin; Blood Volume; Clonidine; Male; Medulla Oblongata; Microinjections; Polyethylene Glycols; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Vasopressins; Yohimbine | 1990 |
Differential contribution of descending serotonergic and noradrenergic systems to central Tyr-D-Ala2-Gly-NMePhe4-Gly-ol5 (DAMGO) and morphine-induced antinociception in mice.
Topics: Analgesia; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Morphine; Serotonin; Yohimbine | 1991 |
Measuring acute changes in adrenergic nerve activity of the heart in the living animal.
Topics: 3-Iodobenzylguanidine; Adrenergic Fibers; Animals; Clonidine; Dogs; Female; Heart; Iodine Radioisotopes; Iodobenzenes; Neurons; Norepinephrine; Radionuclide Imaging; Rats; Rats, Inbred Strains; Time Factors; Tritium; Yohimbine | 1991 |
Interactions of area postrema and solitary tract in the nucleus tractus solitarius.
Topics: Action Potentials; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Medulla Oblongata; Neurons; Rabbits; Reaction Time; Rhombencephalon; Yohimbine | 1991 |
Noradrenaline reuptake and plasma dihydroxyphenylglycol during sustained changes in sympathetic activity in rabbits.
Topics: Animals; Blood Pressure; Brain; Clonidine; Desipramine; Heart Rate; Injections; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rabbits; Sympathetic Nervous System; Time Factors; Yohimbine | 1991 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Practolol; Prazosin; Yohimbine | 1991 |
Possible mechanism of haloperidol-induced enhancement of memory retrieval.
Topics: Animals; Avoidance Learning; Clonidine; Haloperidol; Injections, Intraperitoneal; Male; Memory; Rats; Rats, Inbred Strains; Scopolamine; Yohimbine | 1991 |
Effect of adrenergic agonists on glycogenolysis in primary cultures of astrocytes.
Topics: Alprenolol; Animals; Astrocytes; Cells, Cultured; Clonidine; Glycogen; Isoproterenol; Mice; Norepinephrine; Potassium; Prazosin; Yohimbine | 1990 |
The importance of plasma 3,4-dihydroxyphenylglycol (DOPEG) in analyses of the sympathetic nervous system in vivo.
Topics: Adolescent; Adult; Aged; Animals; Clonidine; Desipramine; Female; Humans; Hypertension; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Rabbits; Sympathetic Nervous System; Synapses; Yohimbine | 1990 |
Prejunctional alpha 1-adrenoceptors modify release of [3H]noradrenaline in the guinea-pig vas deferens.
Topics: Animals; Clonidine; Cocaine; Desoxycorticosterone; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1990 |
Imidazoline-guanidinium receptive site in renal proximal tubule: asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance.
Topics: Amiloride; Animals; Binding Sites; Clonidine; Dioxanes; Dioxins; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Kidney Tubules, Proximal; Magnesium; Male; Potassium; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Yohimbine | 1990 |
Characterization of alpha 2-adrenoceptors in the rat: proximal tubule, renal membrane and whole kidney studies.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Clonidine; In Vitro Techniques; Kidney; Kidney Function Tests; Kidney Tubules, Proximal; Kinetics; Male; Membranes; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Electrically evoked noradrenaline release in the rat hypothalamic paraventricular nucleus studied by in vivo electrochemistry: autoregulation by alpha-2 receptors.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Functional coupling of the alpha 2-adrenergic receptor-adenylate cyclase complex in the pregnant human myometrium.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Binding, Competitive; Clonidine; Colforsin; Cyclic AMP; Dioxanes; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Humans; Idazoxan; Myometrium; Norepinephrine; Pertussis Toxin; Pregnancy; Pregnancy Trimester, Third; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1990 |
Involvement of alpha 2-adrenergic receptors in the vagal reflex-induced tracheal constriction.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Infusions, Intra-Arterial; Injections, Intra-Arterial; Male; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, alpha; Reflex; Trachea; Tracheal Stenosis; Vagus Nerve; Yohimbine | 1990 |
Comorbidity of panic disorder and major depressive disorder: effects on platelet alpha 2 adrenergic receptors.
Topics: Adult; Anxiety Disorders; Binding, Competitive; Blood Platelets; Clonidine; Depressive Disorder; Fear; Female; Humans; Male; Panic; Psychiatric Status Rating Scales; Receptors, Adrenergic; Yohimbine | 1990 |
Adrenergic and cholinergic interaction in central ventilatory control.
Topics: Acetylcholine; Animals; Atropine; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Medulla Oblongata; Propanolamines; Receptors, Adrenergic; Receptors, Cholinergic; Respiration; Respiratory Center; Second Messenger Systems; Yohimbine | 1990 |
Presynaptic alpha adrenoceptor modulation of neurally mediated cholinergic excitatory and nonadrenergic noncholinergic inhibitory responses in guinea pig trachea.
Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Male; Parasympathetic Nervous System; Prazosin; Receptors, Adrenergic, alpha; Trachea; Yohimbine | 1990 |
Inhibitory effects of neuropeptide Y on sympathetic neurotransmission in the rabbit iris-ciliary body.
Topics: Animals; Atropine; Carbachol; Ciliary Body; Clonidine; Drug Interactions; Female; Iris; Male; Neuropeptide Y; Norepinephrine; Pancreatic Polypeptide; Peptide YY; Peptides; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 1990 |
Adrenergic status in anxiety disorders: platelet alpha 2-adrenergic receptor binding, blood pressure, pulse, and plasma catecholamines in panic and generalized anxiety disorder patients and in normal subjects.
Topics: Adult; Agoraphobia; Anxiety Disorders; Arousal; Blood Platelets; Blood Pressure; Clonidine; Epinephrine; Fear; Female; Heart Rate; Humans; Male; Norepinephrine; Panic; Receptors, Adrenergic; Yohimbine | 1990 |
Calcium and alpha-adrenergic regulation of Na-Cl(K) cotransport in rabbit tracheal epithelial cells.
Topics: Animals; Bumetanide; Calcium; Carrier Proteins; Cells, Cultured; Chlorides; Clonidine; Epinephrine; Epithelium; Furosemide; Isoproterenol; Kinetics; Rabbits; Receptors, Adrenergic, alpha; Sodium; Sodium-Potassium-Chloride Symporters; Trachea; Yohimbine | 1990 |
Role of alpha adrenoceptors in opossum internal anal sphincter.
Topics: Anal Canal; Animals; Clonidine; Muscle Contraction; Naphazoline; Opossums; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Pertussis toxin inhibits norepinephrine-stimulated inositol phosphate formation in primary brain cell cultures.
Topics: Animals; Brain; Calcium; Carbachol; Cells, Cultured; Clonidine; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Inositol Phosphates; Norepinephrine; Pertussis Toxin; Phenethylamines; Prazosin; Rats; Receptors, Adrenergic, alpha; Tetralones; Virulence Factors, Bordetella; Yohimbine | 1990 |
Altered responsiveness of central alpha 2-adrenoceptors in aging.
Topics: Aging; Animals; Behavior, Animal; Clonidine; Electroencephalography; Locus Coeruleus; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Clonidine suppresses digitalis-induced ventricular tachycardia in cats.
Topics: Animals; Anti-Arrhythmia Agents; Cats; Clonidine; Digitalis; Female; Heart Ventricles; Male; Plants, Medicinal; Plants, Toxic; Receptors, Adrenergic, alpha; Strophanthidin; Tachycardia; Yohimbine | 1990 |
CNS alpha 2-adrenoceptor induced mydriasis in conscious rats.
Topics: Anesthesia; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Central Nervous System; Clonidine; Light; Male; Methyldopa; Premedication; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Modulation of the release of [3H]norepinephrine from the base and body of the rat urinary bladder by endogenous adrenergic and cholinergic mechanisms.
Topics: Acetylcholine; Animals; Clonidine; In Vitro Techniques; Male; Norepinephrine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Tritium; Urinary Bladder; Yohimbine | 1990 |
Alpha-adrenergic regulation of secretion by tracheal glands.
Topics: Animals; Cats; Clonidine; Dihydroergotoxine; Epinephrine; Female; Glycoconjugates; Isoproterenol; Kinetics; Male; Organ Culture Techniques; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Trachea; Yohimbine | 1990 |
Alpha 2-adrenoceptors in homogenates of rat nasal mucosa.
Topics: Animals; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Nasal Mucosa; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Yohimbine | 1990 |
Intrahypothalamic injections of norepinephrine facilitate feline affective aggression via alpha 2-adrenoceptors.
Topics: Affect; Aggression; Animals; Cats; Clonidine; Electric Stimulation; Female; Hypothalamus; Hypothalamus, Anterior; Male; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Terbutaline; Ventromedial Hypothalamic Nucleus; Vocalization, Animal; Yohimbine | 1990 |
Reserpine induces vascular alpha 2-adrenergic supersensitivity and platelet alpha 2-adrenoceptor up-regulation in dog.
Topics: Adipose Tissue; Animals; Blood Platelets; Blood Pressure; Cardiovascular System; Catecholamines; Cell Membrane; Clonidine; Dioxanes; Dogs; Heart Rate; Idazoxan; Male; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Up-Regulation; Yohimbine | 1990 |
Desensitization and down-regulation of brain alpha 2-adrenoceptors by centrally acting antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Brain; Central Nervous System; Clonidine; Down-Regulation; Guanabenz; Hemodynamics; In Vitro Techniques; Male; Oxazoles; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Yohimbine | 1990 |
Associative influences on tolerance to decreased fixed-interval responding by clonidine.
Topics: Animals; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Male; Rats; Rats, Inbred F344; Reinforcement Schedule; Yohimbine | 1990 |
Clonidine and phenylephrine injected into the lateral hypothalamus inhibits water intake in rats.
Topics: Angiotensin II; Animals; Clonidine; Dehydration; Drinking; Eating; Hypothalamic Area, Lateral; In Vitro Techniques; Injections; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Rats; Yohimbine | 1990 |
In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Dialysis; Electrochemistry; Extracellular Space; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Mianserin; Microchemistry; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine | 1990 |
[Effects of clonidine and norepinephrine on rabbit pulmonary artery strips with or without endothelium].
Topics: Animals; Clonidine; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propranolol; Pulmonary Artery; Rabbits; Yohimbine | 1990 |
Does lithium in vitro and ex vivo alter the release of [3H]noradrenaline from brain tissue and the sensitivity of presynaptic autoreceptors?
Topics: Animals; Brain; Cerebral Cortex; Clonidine; Electric Stimulation; Hippocampus; In Vitro Techniques; Lithium; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Synapses; Yohimbine | 1990 |
Effects of clonidine and yohimbine, alone and in combination with morphine, on supraspinal analgesia.
Topics: Analgesics; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Rats; Rats, Inbred F344; Yohimbine | 1990 |
Effect of intrathecal tizanidine on antinociception and blood pressure in the rat.
Topics: Analgesics; Animals; Blood Pressure; Clonidine; Injections, Spinal; Male; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1990 |
Chloroethylclonidine unmasks a non-alpha-adrenoceptor noradrenaline binding site in the rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic; Yohimbine | 1990 |
Effects of systemic and intracerebroventricular phenylephrine and clonidine on corticosterone secretion in rats.
Topics: Animals; Clonidine; Corticosterone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
The effects of phosphatidylserine on the decreased cardiovascular response to clonidine microinfused into the nucleus tractus solitarii of old rats.
Topics: Aging; Animals; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Infusions, Intravenous; Male; Medulla Oblongata; Methoxamine; Phentolamine; Phosphatidylserines; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
The properties of the clonidine withdrawal response of guinea-pig isolated ileum.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Enkephalin, Methionine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Norepinephrine; Phentolamine; Substance P; Substance Withdrawal Syndrome; Yohimbine | 1985 |
Alpha-adrenoceptors and muscarinic receptors in the isolated human prostate.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prostate; Prostatic Hyperplasia; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Yohimbine | 1985 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Labetalol; Male; Phenylephrine; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Vasodilation; Yohimbine | 1985 |
Alpha 2 adrenergic receptors in hyperplastic human prostate: identification and characterization using [3H] rauwolscine.
Topics: Binding, Competitive; Cerebral Cortex; Clonidine; DNA; Humans; Kinetics; Male; Nordefrin; Prazosin; Prostate; Prostatic Hyperplasia; Radioligand Assay; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1986 |
Influence of the alpha-2 agonist oxaminozoline (S3341) on firing rate of central noradrenergic and serotonergic neurons in the rat. Comparison with clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Electrophysiology; Iontophoresis; Locus Coeruleus; Male; Neurons; Norepinephrine; Oxazoles; Prazosin; Raphe Nuclei; Rats; Rilmenidine; Serotonin; Yohimbine | 1986 |
Substance P-induced long-term blockade of spinal adrenergic analgesia: reversal by morphine and naloxone.
Topics: Analgesia; Animals; Clonidine; Kinetics; Male; Morphine; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors; Yohimbine | 1987 |
Alpha 2-adrenergic receptors in brown adipose tissue of infant rats--II. Studies on function and regulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adipose Tissue, Brown; Animals; Clonidine; Colforsin; Hydroxydopamines; Kinetics; Lipolysis; Oxidopamine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy, Chemical; Virulence Factors, Bordetella; Yohimbine | 1988 |
The brain's own clonidine: purification and characterization of endogenous clonidine displacing substance from brain.
Topics: Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Clonidine; Electric Stimulation; Membranes; Molecular Weight; Platelet Aggregation; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Alpha-adrenergic and serotonergic mechanisms in the human digit.
Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Fingers; Humans; Ketanserin; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reflex; Regional Blood Flow; Serotonin; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction; Yohimbine | 1988 |
An evidence for presynaptic excitatory alpha 2-adrenergic receptors in frog myocardium.
Topics: Adrenergic Fibers; Animals; Clonidine; Electric Stimulation; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Myocardium; Rana temporaria; Receptors, Adrenergic, alpha; Synaptic Transmission; Ventricular Function; Yohimbine | 1988 |
Dietary Ca2+ supplementation prevents the exaggerated responsiveness of anterior hypothalamic alpha 2-adrenoceptors in NaCl-loaded spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium, Dietary; Clonidine; Diet; Heart Rate; Hypertension; Hypothalamus, Anterior; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Sodium Chloride; Yohimbine | 1989 |
Differential inhibitory effects of nitroglycerin on contractile responses to the alpha-adrenoceptor agonists, methoxamine and clonidine, in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Radioisotopes; Clonidine; Egtazic Acid; In Vitro Techniques; Lanthanum; Male; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Phenoxybenzamine; Potassium; Prazosin; Rabbits; Yohimbine | 1989 |
Alpha 2-adrenergic stimulation counteracts the metabolic effects of vasoactive intestinal peptide in isolated rat enterocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetyl-CoA Carboxylase; Animals; Cells, Cultured; Clonidine; Epinephrine; Intestinal Mucosa; Male; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Propranolol; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
[Inhibitory action of intracerebroventricular injections of norepinephrine and clonidine on ventricular extrasystoles induced by stimulating hypothalamus in rabbits].
Topics: Animals; Cardiac Complexes, Premature; Clonidine; Electric Stimulation; Female; Hypothalamus; Injections, Intraventricular; Male; Norepinephrine; Phentolamine; Prazosin; Rabbits; Yohimbine | 1989 |
Effects of octopaminergic substances on the labellar lobe spreading response in the blowfly Protophormia terraenovae.
Topics: Action Potentials; Animals; Central Nervous System; Clonidine; Diptera; Eating; Electrophysiology; Muscles; Octopamine; Receptors, Adrenergic; Receptors, Biogenic Amine; Taste Buds; Yohimbine | 1989 |
Modulation of retinal aromatic L-amino acid decarboxylase via alpha 2 adrenoceptors.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Clonidine; Cycloheximide; Darkness; Dihydroxyphenylalanine; Kinetics; Light; Male; Oxymetazoline; Phentolamine; Piperoxan; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Retina; Yohimbine | 1989 |
Audiogenic stress response: behavioral characteristics and underlying monoamine mechanisms.
Topics: Adrenergic Fibers; Animals; Auditory Pathways; Behavior, Animal; Clonidine; Hippocampus; Male; Motor Activity; Nitrogen Mustard Compounds; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stress, Physiological; Yohimbine | 1989 |
Identification of alpha 2-adrenergic receptor sites in human retinoblastoma (Y-79) and neuroblastoma (SH-SY5Y) cells.
Topics: Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; Humans; Neuroblastoma; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Retinoblastoma; Sodium; Tritium; Tumor Cells, Cultured; Yohimbine | 1989 |
Mechanism of neuropeptide Y inhibition of vasopressin action in rat cortical collecting tubule.
Topics: Animals; Arginine Vasopressin; Clonidine; Cyclic AMP; Drug Interactions; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Neuropeptide Y; Pertussis Toxin; Prazosin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella; Yohimbine | 1989 |
Alpha 2-adrenergic modulation of synaptic excitability in the rat nucleus tractus solitarius.
Topics: Action Potentials; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Medulla Oblongata; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Alpha 2- and beta-adrenergic receptors and adenosine A1 receptor of FRTL-5 rat thyroid cells in relation to fucosyl GM1 ganglioside.
Topics: Animals; Cell Line; Clonidine; Cyclic AMP; G(M1) Ganglioside; Isoproterenol; Kinetics; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Purinergic; Thyroid Gland; Thyrotropin; Yohimbine | 1989 |
Effects of Bordetella pertussis toxin on catecholamine inhibition of insulin release from intact and electrically permeabilized rat islets.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cells, Cultured; Clonidine; Cyclic AMP; Female; Insulin; Islets of Langerhans; Male; Norepinephrine; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella; Yohimbine | 1989 |
Acute and chronic effects of the pesticide amitraz on alpha 2-adrenoceptors in mouse brain.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Insecticides; Male; Mice; Receptors, Adrenergic, alpha; Toluidines; Tritium; Yohimbine | 1989 |
Modulation of histamine release and synthesis in the brain mediated by alpha 2-adrenoceptors.
Topics: Animals; Brain; Clonidine; Histamine; Histamine Antagonists; In Vitro Techniques; Norepinephrine; Potassium; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate.
Topics: Animals; Carbolines; Chlorpromazine; Clonidine; Conditioning, Operant; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Yohimbine | 1989 |
Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats.
Topics: Analgesics; Animals; Blood Pressure; Cats; Clonidine; Decerebrate State; Drug Combinations; Female; Injections, Spinal; Male; Morphine; Neurons; Pain; Receptors, Adrenergic, alpha; Spinal Cord; Spinothalamic Tracts; Synaptic Transmission; Yohimbine | 1989 |
Presynaptic alpha 2-adrenoceptors modulate the release of [3H]noradrenaline from rat spinal cord dorsal horn neurones.
Topics: Animals; Benzylamines; Calcium; Clonidine; Cocaine; Male; Neurons; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Spinal Cord; Tetrodotoxin; Tritium; Yohimbine; Zimeldine | 1989 |
Effect of l-ephedrine on cholinergic neurotransmission in the isolated guinea pig ileum.
Topics: Animals; Clonidine; Ephedrine; Female; Guinea Pigs; Hydroxydopamines; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Oxidopamine; Parasympathetic Nervous System; Sulpiride; Synaptic Transmission; Tyramine; Yohimbine | 1989 |
[Effect of clonidine on the schedule-controlled performance action of two benzodiazepine receptor agonists].
Topics: Animals; Bicuculline; Clonidine; Conditioning, Operant; Diazepam; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reinforcement Schedule; Yohimbine | 1989 |
Ontogeny of noradrenergic effects on ultrasonic vocalizations in rat pups.
Topics: Aging; Animals; Animals, Newborn; Arousal; Brain; Clonidine; Emotions; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Social Isolation; Ultrasonics; Vocalization, Animal; Yohimbine | 1989 |
Relationship of calcium and adenylate cyclase messenger systems in rat brain synaptosomes.
Topics: Adenylyl Cyclases; Animals; Brain; Calcium; Clonidine; Cyclic AMP; Male; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Second Messenger Systems; Synaptosomes; Yohimbine | 1989 |
Alpha-adrenergic influences on neuronal responses to visceral afferent input in the nucleus tractus solitarius.
Topics: Animals; Clonidine; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; In Vitro Techniques; Male; Medulla Oblongata; Methoxamine; Neurons, Afferent; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Beneficial effects of alpha 2-adrenoceptor activity on ischemic myocardium during coronary hypoperfusion in dogs.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Disease; Cyclic AMP; Dogs; Hemodynamics; Lactates; Myocardial Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Propranolol; Receptors, Adrenergic, alpha; Theophylline; Vasodilation; Yohimbine | 1989 |
Estimation of pA2 values at presynaptic alpha 2-autoreceptors in rabbit and rat brain cortex in the absence of autoinhibition.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Kinetics; Male; Nordefrin; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1989 |
Effect of drugs acting on monoaminergic and cholinergic systems on the quantified EEG of rats.
Topics: Animals; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Haloperidol; Locus Coeruleus; Male; Physostigmine; Piracetam; Psychotropic Drugs; Rats; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1989 |
The effects of alpha 2-adrenergic agonism with clonidine on the pulmonary and collateral resistances in the canine lung challenged with histamine.
Topics: Airway Resistance; Animals; Clonidine; Dogs; Histamine; Isoproterenol; Lung; Male; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Inositol phospholipid hydrolysis and potentiation of cyclic AMP formation by noradrenaline in rat cerebral cortex slices are not mediated by the same alpha-adrenoceptor subtypes.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Hydrolysis; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sugar Phosphates; Theophylline; Yohimbine | 1989 |
Interactions of full and partial agonists with HT29 cell alpha 2-adrenoceptor: comparative study of [3H]UK-14,304 and [3H]clonidine binding.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guanylyl Imidodiphosphate; Kinetics; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Tritium; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Yohimbine | 1989 |
Effect of phorbol esters on noradrenaline release from cerebral arteries.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Cats; Cerebral Arteries; Clonidine; Electric Stimulation; Female; Male; Norepinephrine; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Yohimbine | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
Effect of alpha-2 adrenergic receptor stimulation on short-circuit current across isolated skin of the toad Bufo arenarum.
Topics: Animals; Bufo arenarum; Clonidine; Dose-Response Relationship, Drug; Electricity; Female; In Vitro Techniques; Male; Receptors, Adrenergic, alpha; Skin; Skin Physiological Phenomena; Yohimbine | 1989 |
An in vivo evaluation of alpha adrenergic receptors in canine prostate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Clonidine; Dogs; Dose-Response Relationship, Drug; Epinephrine; Male; Prazosin; Pressure; Prostate; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Alpha 2-adrenoceptor in HT29 human colon adenocarcinoma cell-line: study of [3H](-)-adrenaline binding.
Topics: Adenocarcinoma; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Cell Line; Cell Membrane; Clonidine; Colonic Neoplasms; Epinephrine; Guanylyl Imidodiphosphate; Humans; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Human fat cell alpha-2 adrenoceptors. II. Comparative study of partial and full agonist binding parameters using [3H]clonidine and [3H]UK-14,304.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Allosteric Regulation; Binding, Competitive; Brimonidine Tartrate; Clonidine; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Magnesium; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Uptake inhibitors do not change the effect of imidazoline alpha 2-adrenoceptor agonists on transmitter release evoked by single pulse stimulation in mouse vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Desipramine; Imidazoles; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Normetanephrine; Phenethylamines; Vas Deferens; Yohimbine | 1989 |
Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice.
Topics: Adenosine; Adrenergic alpha-Antagonists; Aminophylline; Animals; Anticonvulsants; Clonidine; Habituation, Psychophysiologic; Methysergide; Mice; Mice, Inbred DBA; Piperoxan; Yohimbine | 1989 |
Yohimbine's anxiogenic action: evidence for noradrenergic and dopaminergic sites.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Animals; Anxiety; Apomorphine; Azepines; Benzazepines; Clonidine; Dopamine Agents; Ergolines; Guanfacine; Guanidines; Learning; Male; Norepinephrine; Phenylacetates; Phenylephrine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Yohimbine | 1989 |
Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2-dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland.
Topics: Acetyltransferases; Adrenergic beta-Antagonists; Animals; Apomorphine; Arylamine N-Acetyltransferase; Chickens; Clonidine; Darkness; Dopamine Antagonists; Light; Male; Melatonin; Pineal Gland; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Reference Values; Retina; Spiperone; Yohimbine | 1989 |
Effects of botulinum A toxin on presynaptic modulation of evoked transmitter release.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Botulinum Toxins; Clonidine; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Rabbits; Serotonin; Synapses; Yohimbine | 1989 |
Action of clonidine on micturitional reflexes in decerebrate cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Central Nervous System; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Reflex; Urination; Yohimbine | 1989 |
Acute and long-term regulation of brain alpha 2-adrenoceptors after manipulation of noradrenergic transmission in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Clonidine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptic Transmission; Yohimbine | 1989 |
Clonidine modulates dopamine cell firing in rat ventral tegmental area.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dopamine; Idazoxan; Male; Neurons; Rats; Tegmentum Mesencephali; Yohimbine | 1989 |
Mechanisms of chronotropic cardiac effects of alinidine and plasma concentration-response relationships in the conscious dog with chronic atrioventricular block.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Clonidine; Dogs; Drug Interactions; Electrocardiography; Female; Heart Block; Heart Rate; Male; Phenoxybenzamine; Phentolamine; Receptors, Muscarinic; Yohimbine | 1989 |
An in vivo procedure for the selective inactivation of rat brain cerebral cortical alpha-adrenoceptors using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ).
Topics: Adrenergic alpha-Antagonists; Animals; Cell Membrane; Cerebral Cortex; Clonidine; Cyclic AMP; Dihydroalprenolol; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Prazosin; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Characterization of autonomic receptors in neonatal urinary tract smooth muscle.
Topics: Adrenergic Agonists; Animals; Animals, Newborn; Carbachol; Clonidine; Dihydroalprenolol; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prazosin; Quinuclidinyl Benzilate; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Urinary Tract; Yohimbine | 1989 |
Detection and characterization of 3H-clonidine binding sites in coated vesicles isolated from bovine brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Cattle; Clonidine; Imidazoline Receptors; In Vitro Techniques; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Subcellular Fractions; Yohimbine | 1989 |
[Selectivity of alpha 2-adrenergic agonists for the imidazoline-guanidine and alpha 2-adrenergic receptors].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Guanfacine; Guanidines; Idazoxan; Kidney Tubules, Proximal; Male; Oxazoles; Phenylacetates; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Yohimbine | 1989 |
Effects of St-587 on the alpha-adrenoceptors in the bisected rat vas deferens.
Topics: Animals; Clonidine; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Prazosin; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1989 |
The paradox of alpha 2 adrenergic regulation of prolactin (PRL) secretion. II. PRL-releasing action of the alpha 2 receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Growth Hormone; Male; Nervous System; Prolactin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Stimulation of alpha 1-adrenoceptors increases electrically evoked [3H]acetylcholine release from the rat phrenic nerve.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; Oxymetazoline; Phenylephrine; Phrenic Nerve; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Imidazolinic radioligands for the identification of hamster adipocyte alpha 2-adrenoceptors.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cricetinae; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipolysis; Male; Mesocricetus; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Prostaglandins, alpha-adrenergic receptors and lipolysis in hamster fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dinoprostone; Epididymis; Epoprostenol; Isoproterenol; Lipolysis; Male; Prostaglandins E; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Endogenous noradrenaline impairs the prostaglandin-induced inhibition of noradrenaline release.
Topics: Animals; Cerebral Cortex; Clonidine; Dinoprostone; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Male; Norepinephrine; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Does anxiety underly imidazole-induced behavioural effects in the rat?
Topics: Animals; Anxiety; Arousal; Behavior, Animal; Blood Pressure; Clonidine; Diazepam; Emotions; Hemodynamics; Imidazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Social Behavior; Yohimbine | 1989 |
Central administration of neuropeptide Y induces hypothermia in mice. Possible interaction with central noradrenergic systems.
Topics: Animals; Body Temperature; Cerebral Ventricles; Clonidine; Injections, Intraventricular; Male; Mice; Neuropeptide Y; Norepinephrine; Reference Values; Yohimbine | 1989 |
Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits.
Topics: Animals; Blood Pressure; Brain; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Nitroprusside; Norepinephrine; Peripheral Nerves; Phenylephrine; Pressoreceptors; Rabbits; Sympathetic Nervous System; Synapses; Yohimbine | 1989 |
Plasma 3,4-dihydroxyphenylglycol as a tool to assess the role of neuronal uptake in the anaesthetized rabbit.
Topics: Anesthesia; Animals; Clonidine; Female; Glycols; Half-Life; Kinetics; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rabbits; Yohimbine | 1989 |
New isoxazole derivatives provided with antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Chemical Phenomena; Chemistry; Clonidine; In Vitro Techniques; Isoxazoles; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxazoles; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vas Deferens; Yohimbine | 1989 |
[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord].
Topics: Animals; Cats; Clonidine; Mesencephalon; Naloxone; Neurons; Nociceptors; Pain; Prazosin; Spinal Cord; Yohimbine | 1989 |
Interaction of clonidine and morphine with lidocaine in mice and rats.
Topics: Animals; Blood Gas Analysis; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Hypoxia; Lethal Dose 50; Lidocaine; Male; Mice; Morphine; Rats; Yohimbine | 1989 |
Characterization of alpha-adrenoceptor subtypes involved in regulation of ureteral fluid transport.
Topics: Animals; Clonidine; Dogs; Female; Male; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Ureter; Yohimbine | 1987 |
Characterization of dog fat cell adrenoceptors: variations in alpha-2 and beta adrenergic receptors distribution according to the extent of the fat deposits and the anatomical location.
Topics: Adipose Tissue; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dihydroalprenolol; Dogs; Epinephrine; Humans; Isoproterenol; Lipolysis; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1987 |
Clonidine suppression and its adrenoreceptor mediation in schedule-induced polydipsia.
Topics: Adrenal Medulla; Animals; Behavior, Animal; Catecholamines; Cerebral Cortex; Clonidine; Drinking Behavior; Injections, Intraventricular; Male; Rats; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1987 |
Characterisation of the alpha-adrenoceptors of the rat renal vascular bed.
Topics: Animals; Azepines; Clonidine; Dopamine; In Vitro Techniques; Kidney; Male; Nordefrin; Perfusion; Phenylephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1987 |
Central alpha 2 adrenoceptor-mediated pancreatic exocrine response to yohimbine in anesthetized dog.
Topics: Animals; Bicarbonates; Clonidine; Deoxyglucose; Dogs; Dose-Response Relationship, Drug; Female; Male; Pancreas; Pancreatic Juice; Proteins; Receptors, Adrenergic, alpha; Secretin; Stimulation, Chemical; Yohimbine | 1987 |
The effect of hyperthyroidism and hypothyroidism on alpha 1- and alpha 2-adrenergic responsiveness in rat aortic smooth muscle.
Topics: Animals; Aorta; Clonidine; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Thyroid Hormones; Thyroxine; Yohimbine | 1987 |
Possible catecholaminergic-opioidergic control of blood pressure during muscular contraction.
Topics: Animals; Blood Pressure; Cats; Clonidine; Dose-Response Relationship, Drug; Isometric Contraction; Muscle Contraction; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Opioid; Yohimbine | 1987 |
Evaluation of isomers of octopamine for in vitro alpha-adrenergic stimulation of the aortic smooth muscle from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Clonidine; Isomerism; Kinetics; Muscle, Smooth, Vascular; Norepinephrine; Octopamine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine | 1987 |
Protection of presynaptic alpha-adrenoceptors against irreversible blockade by phenoxybenzamine: preservation of the modulatory effects of exogenous noradrenaline and yohimbine.
Topics: Animals; Binding Sites; Cerebral Cortex; Clonidine; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Norepinephrine; Phenoxybenzamine; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Modulation of gamma-[3H]aminobutyric acid release from rat cortical slices by alpha 2-adrenoceptors.
Topics: Animals; Calcium; Clonidine; gamma-Aminobutyric Acid; Guanabenz; In Vitro Techniques; Male; Norepinephrine; Occipital Lobe; Parietal Lobe; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
A low molecular weight brain substance interacts, similarly to clonidine, with alpha 2-adrenoceptors of human platelets.
Topics: Animals; Binding, Competitive; Blood Platelets; Brain; Cattle; Clonidine; Cyclic AMP; Humans; In Vitro Techniques; Molecular Weight; Platelet Aggregation; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.
Topics: Algorithms; Animals; Binding, Competitive; Cattle; Clonidine; Hydrogen-Ion Concentration; Prazosin; Quinolizines; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine | 1988 |
Adrenoceptor occupancy in isolated human fat cells and its relationship with lipolysis rate.
Topics: Adipose Tissue; Adult; Clonidine; Female; Humans; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kinetics; Lipolysis; Male; Middle Aged; Phenoxybenzamine; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1988 |
An alpha 2-adrenergic mode of action of chlordimeform on rat visual function.
Topics: Amidines; Animals; Body Temperature; Chlorphenamidine; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials, Visual; Insecticides; Male; Rats; Reaction Time; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Ca2+ channel blockers interact with alpha 2-adrenergic receptors in rabbit ileum.
Topics: Animals; Calcium Channel Blockers; Clonidine; Diltiazem; Egtazic Acid; Electrolytes; Ileum; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Membrane Potentials; Nifedipine; Rabbits; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1988 |
Noradrenergic mechanisms in mediation of stress-induced hyperalgesia in rats.
Topics: Analgesia; Animals; Clonidine; Diazepam; Norepinephrine; Pain; Rats; Receptors, Adrenergic, alpha; Stress, Physiological; Vibration; Yohimbine | 1988 |
Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Conductivity; Epinephrine; Isoproterenol; Phenylephrine; Pigment Epithelium of Eye; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Cholecystokinin modulation of [3H]noradrenaline release from superfused hypothalamic slices.
Topics: Animals; Clonidine; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sincalide; Yohimbine | 1988 |
Synthesis and structure-activity relationships of 2-sulfonamido-1,3,4,6,7,11b alpha-hexahydro-2H-benzo[a]quinolizines as alpha 2-adrenoceptor antagonists.
Topics: Animals; Chemical Phenomena; Chemistry; Clonidine; Dioxanes; Idazoxan; Male; Methoxamine; Molecular Conformation; Muscle Contraction; Muscles; Quinolizines; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Vas Deferens; Yohimbine | 1988 |
Role of alpha 1- and alpha 2-adrenoceptors in catecholamine-induced hyperglycaemia, lipolysis and insulin secretion in conscious fasted rabbits.
Topics: Animals; Catecholamines; Clonidine; Hyperglycemia; Insulin; Insulin Secretion; Lipolysis; Male; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Alpha 2-adrenoceptor activity exerts dual control of coronary blood flow in canine coronary artery.
Topics: Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Vessels; Dogs; Norepinephrine; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Vasodilation; Yohimbine | 1988 |
Role of alpha-adrenoceptor subtypes mediating sympathetic vasoconstriction in human digits.
Topics: Adult; Clonidine; Female; Fingers; Humans; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1988 |
Sites of clonidine action to inhibit gut propulsion in mice: demonstration of a central component.
Topics: Animals; Clonidine; Gastrointestinal Transit; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Prazosin; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1988 |
Opioid-noradrenergic interactions in the neurohypophysis. II. Does noradrenaline mediate the actions of endogenous opioids on oxytocin and vasopressin release?
Topics: Animals; Arginine Vasopressin; Clonidine; Electric Stimulation; Endorphins; In Vitro Techniques; Isoproterenol; Male; Naloxone; Norepinephrine; Oxytocin; Pituitary Gland, Posterior; Rats; Receptors, Opioid; Yohimbine | 1988 |
[N-2-chloroethyl-N-ethyl-2-bromobenzylamine (DSP4) increases the liberation of 3H-noradrenaline produced by depolarization of the nerve ending].
Topics: Animals; Benzylamines; Cerebral Cortex; Clonidine; Female; Male; Nerve Endings; Norepinephrine; Phentolamine; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Secretory Rate; Stimulation, Chemical; Vas Deferens; Yohimbine | 1988 |
Behavioural and electrocortical spectrum-power effects of clonidine and related drugs given into several areas of the rat brain.
Topics: Animals; Behavior, Animal; Clonidine; Electroencephalography; Injections, Intraventricular; Locus Coeruleus; Male; Methoxamine; Microinjections; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1988 |
Unique presynaptic alpha 2-receptor selectivity and specificity of the antihypertensive agent moxonidine.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cerebral Cortex; Chemical Phenomena; Chemistry; Clonidine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Heart Rate; Imidazoles; Ligands; Male; Norepinephrine; Papillary Muscles; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Venae Cavae; Yohimbine | 1988 |
Idazoxan and brain alpha 2-adrenoceptors in the rabbit.
Topics: Animals; Brain; Clonidine; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Injections, Intravenous; Rabbits; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1988 |
Comparison of drugs with different selectivity for central alpha 1-and alpha 2-adrenoceptors in animal models of epilepsy.
Topics: Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1987 |
Dose selective dissociation of water and solute excretion after renal alpha-2 adrenoceptor stimulation.
Topics: Animals; Blood Pressure; Body Water; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasopressins; Yohimbine | 1988 |
Effect of DSP-4, a noradrenergic neurotoxin, on sleep and wakefulness and sensitivity to drugs acting on adrenergic receptors in the rat.
Topics: Animals; Benzylamines; Brain; Circadian Rhythm; Clenbuterol; Clonidine; Male; Methoxamine; Neurotoxins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sleep Stages; Sleep, REM; Wakefulness; Yohimbine | 1988 |
Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.
Topics: Adenosine; Aggression; Animals; Behavior, Animal; Caffeine; Carbamazepine; Clonidine; Haloperidol; Male; Mice; Prazosin; Receptors, Cell Surface; Yohimbine | 1988 |
Alpha-2-adrenoceptor-mediated inhibition of vagally induced gastric acid secretion with the anti-ulcer agent DQ-2511.
Topics: Animals; Anti-Ulcer Agents; Benzamides; Clonidine; Gastric Acid; Gastric Mucosa; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Vagus Nerve; Yohimbine | 1988 |
Norepinephrine inhibits calcium action potential through alpha 2-adrenoceptors in rabbit vesical parasympathetic neurons.
Topics: Action Potentials; Animals; Brimonidine Tartrate; Calcium; Clonidine; Ganglia, Parasympathetic; Male; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1988 |
[Clonidine inhibition effect on synaptic transmission of guinea pig celiac ganglia].
Topics: Animals; Clonidine; Female; Ganglia, Sympathetic; Guinea Pigs; Male; Synaptic Transmission; Yohimbine | 1988 |
Microinfusion of clonidine and yohimbine into locus coeruleus alters EEG power spectrum: effects of aging and reversal by phosphatidylserine.
Topics: Aging; Animals; Clonidine; Cortical Synchronization; Electroencephalography; Locus Coeruleus; Male; Phosphatidylserines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Enhancement of endogenous GABA release from rat synaptosomal preparations is mediated by alpha 2-adrenoceptors pharmacologically different from alpha 2-autoreceptors.
Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Male; Mianserin; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1988 |
Differences in the ability of yohimbine to antagonize the hypotensive effect of clonidine in normotensive and spontaneously hypertensive anesthetized rats.
Topics: Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
[Effects of agonist and inverse agonist of central benzodiazepine receptors on discriminative yohimbine stimulation].
Topics: Animals; Carbolines; Clonidine; Convulsants; Diazepam; Discrimination Learning; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Yohimbine | 1988 |
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine | 1985 |
Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Calcium Chloride; Clonidine; Endothelium; In Vitro Techniques; Male; Methoxamine; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Yohimbine | 1985 |
Antagonism by clonidine of the adenosine-induced inhibition of the twitch contraction of the guinea-pig Oddi sphincter.
Topics: Adenosine; Alprostadil; Ampulla of Vater; Animals; Clonidine; Dipyridamole; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Prostaglandins E; Reserpine; Sphincter of Oddi; Theophylline; Yohimbine | 1985 |
Interaction between the inhibitory action of acetylcholine and the alpha-adrenoceptor autoinhibitory feedback system on release of [3H]-noradrenaline from rat atria and rabbit ear artery.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Arteries; Catecholamines; Clonidine; Dioxanes; Ear; Electric Stimulation; Feedback; Female; Heart Atria; Idazoxan; Imidazolines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Norepinephrine; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Increased investigative activity after presynaptic dopaminergic stimulation measured by a fixed-interval recording procedure.
Topics: Adrenergic alpha-Agonists; alpha-Methyltyrosine; Animals; Apomorphine; Azepines; Clonidine; Drug Interactions; Exploratory Behavior; Haloperidol; Male; Methyltyrosines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Stimulation, Chemical; Yohimbine | 1985 |
Affinities of adrenergic drugs for alpha 2-adrenoceptors in dog saphenous vein in comparison with those in rat brain or human platelets.
Topics: Adrenergic alpha-Agonists; Animals; Blood Platelets; Brain; Clonidine; Dogs; Epinephrine; Guanabenz; Humans; Naphazoline; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Saphenous Vein; Tolazoline; Tritium; Yohimbine | 1985 |
Characterization of dog platelet alpha-adrenergic receptor: lack of in vivo down regulation by adrenergic agonist treatments.
Topics: Adenosine Diphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Platelets; Cell Membrane; Clonidine; Dogs; Female; Kinetics; Male; Platelet Aggregation; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Sodium chloride-induced partial inhibition in vivo of alpha 2-adrenoceptor agonist function.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Male; Mannitol; Nephrectomy; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Chloride; Yohimbine | 1985 |
Peripheral cardiovascular alpha- and beta-adrenergic effects of some hypotensive and bradycardic arylalkyl imidazole derivatives in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart; Imidazoles; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1985 |
Subsensitivity of enteric cholinergic neurones to alpha 2-adrenoceptor agonists after chronic sympathetic denervation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Clonidine; Colon; Dopamine; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle Denervation; Norepinephrine; Sympathetic Nervous System; Yohimbine | 1985 |
Apparent pA2 estimates for an antinociceptive receptor.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Mice; Morphine; Naloxone; Nociceptors; Reaction Time; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Pharmacological characterization of alpha-adrenergic receptor subtypes mediating contraction in human mesenteric arteries and veins.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Drug Interactions; Female; Humans; Male; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phentolamine; Prazosin; Vasodilation; Yohimbine | 1985 |
Location of the mechanism of the clonidine withdrawal tachycardia in rats.
Topics: Animals; Blood Pressure; Clonidine; Injections, Intraventricular; Injections, Subcutaneous; Male; Oxymetazoline; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tachycardia; Time Factors; Yohimbine | 1985 |
Autoregulation of endogenous epinephrine release via presynaptic adrenoceptors in the rat hypothalamic slice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzylamines; Butoxamine; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Epinephrine; Homeostasis; Hypothalamus; Isoproterenol; Male; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sulpiride; Yohimbine | 1985 |
Arylazide photoaffinity probe for alpha 2-adrenoceptors.
Topics: Absorption; Adrenergic alpha-Antagonists; Benzazepines; Binding, Competitive; Blood Platelets; Clonidine; Humans; Membranes; Phentolamine; Photolysis; Prazosin; Receptors, Adrenergic, alpha; Tritium; Ultraviolet Rays; Yohimbine | 1985 |
Discriminative stimulus properties of xylazine in rat: discriminability and effects of putative alpha-2 adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Discrimination Learning; Idazoxan; Lisuride; Lysergic Acid Diethylamide; Male; Piperoxan; Rats; Rats, Inbred Strains; Thiazines; Xylazine; Yohimbine | 1985 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Agonist and antagonist binding to alpha 2-adrenergic receptors in purified membranes from human platelets. Implications of receptor-inhibitory nucleotide-binding protein stoichiometry.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Clonidine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; NAD; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Alpha 1-adrenergic blockade increases coronary blood flow during coronary hypoperfusion.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Coronary Circulation; Dogs; Drug Synergism; Female; Male; Methoxamine; Perfusion; Prazosin; Propranolol; Yohimbine | 1985 |
Effects of alpha-adrenoceptor agonists and antagonists on insulin secreting cells and pancreatic blood vessels: comparative study.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Clonidine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Yohimbine | 1985 |
Rat brain alpha 2-pre- and postsynaptic receptors are different or differently modulated?
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Drug Administration Schedule; Male; Mianserin; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Synaptosomes; Yohimbine | 1985 |
Alpha 2-adrenergic binding and action in human adipocytes. Comparison between binding to plasma membrane preparations and to intact adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Humans; In Vitro Techniques; Kinetics; Lipolysis; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Responses to norepinephrine resistant to inhibition by alpha and beta adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Nordefrin; Norepinephrine; Receptors, Adrenergic; Reserpine; Yohimbine | 1986 |
Imidazole has similar behavioural effects to yohimbine.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Azepines; Behavior, Animal; Body Temperature; Chickens; Clonidine; Haloperidol; Hypnotics and Sedatives; Imidazoles; Male; Penile Erection; Prazosin; Rats; Sexual Behavior, Animal; Sleep; Time Factors; Yohimbine | 1986 |
Evidence that serotonin receptors are involved in the anticonvulsant effect of yohimbine in mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Azepines; Clonidine; Dioxanes; Electroshock; Idazoxan; Male; Metergoline; Methysergide; Mice; Quipazine; Receptors, Serotonin; Serotonin Antagonists; Yohimbine | 1986 |
Plasma thyrotrophin (TSH) response to intrahypothalamic injection of an alpha 2-adrenergic receptor agonist (clonidine).
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Hypothalamus; Male; Microinjections; Phenoxybenzamine; Rats; Rats, Inbred Strains; Thyrotropin; Yohimbine | 1986 |
Discriminative stimulus properties of clonidine: substitution by ergot derivatives.
Topics: Adrenergic alpha-Agonists; Animals; Apomorphine; Blood Pressure; Clonidine; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Lisuride; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists; Yohimbine | 1985 |
Phenoxybenzamine partially inhibits alpha 2-adrenoceptors without affecting their presynaptic function.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; In Vitro Techniques; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
The effects of yohimbine on exploratory and locomotor behaviour are attributable to its effects at noradrenaline and not at benzodiazepine receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepinones; Chlordiazepoxide; Clonidine; Drug Interactions; Exploratory Behavior; Flumazenil; Male; Motor Activity; Rats; Receptors, GABA-A; Yohimbine | 1986 |
Does alprazolam, in contrast to diazepam, activate alpha 2-adrenoceptors involved in the regulation of rat growth hormone secretion?
Topics: Adrenergic alpha-Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Clonidine; Diazepam; Dioxanes; Growth Hormone; Idazoxan; Kinetics; Male; Rats; Receptors, Adrenergic, alpha; Reserpine; Yohimbine | 1986 |
Critical assessment of the platelet adenylate cyclase system as a potential model for testing alpha 2 adrenergic activity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Clonidine; Humans; Kinetics; Pertussis Toxin; Platelet Aggregation; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1986 |
Presynaptic alpha-adrenoceptor mediated inhibition of the neurogenic cholinergic contraction in the isolated intestinal bulb of the carp (Cyprinus carpio).
Topics: Animals; Atropine; Carps; Catecholamines; Clonidine; Cyprinidae; Electric Stimulation; Epinephrine; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Yohimbine | 1986 |
Secretion of catecholamines from the perfused adrenal gland of the rat is not regulated by alpha-adrenoceptors.
Topics: Adrenal Glands; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Catecholamines; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Nicotine; Perfusion; Phentolamine; Phenylephrine; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Effects of morphine and clonidine on sulphobromophthalein disposition in mice.
Topics: Animals; Bile; Clonidine; Liver; Male; Mice; Morphine; Naloxone; Sulfobromophthalein; Yohimbine | 1986 |
Alpha-2 adrenergic agonists inhibit basal and stimulated osmotic water permeability in toad skin.
Topics: Adrenergic alpha-Agonists; Animals; Bufo arenarum; Clonidine; Female; In Vitro Techniques; Male; Norepinephrine; Osmolar Concentration; Oxytocin; Permeability; Prazosin; Propranolol; Skin; Skin Physiological Phenomena; Water; Yohimbine | 1986 |
Noradrenaline modulates the release of [14C]glutamate from dentate but not from CA1/CA3 slices of rat hippocampus.
Topics: Animals; Calcium; Clonidine; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phenylephrine; Potassium; Propranolol; Pyramidal Tracts; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Male; Mydriatics; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Vas Deferens; Yohimbine | 1986 |
The effects of alpha-2 agonists and antagonists on gastric acid secretion.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Gastric Juice; Guanabenz; Guinea Pigs; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tolazoline; Xylazine; Yohimbine | 1986 |
Pharmacological characterization of the postsynaptic alpha-adrenoceptors in human uterine artery.
Topics: Arteries; Clonidine; Drug Interactions; Female; Humans; Kinetics; Naphazoline; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Uterus; Vasoconstriction; Yohimbine | 1986 |
Dissociation of locomotor impairment from mydriasis evoked by clonidine injected into cat's rostral hypothalamus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Female; Injections; Motor Activity; Phentolamine; Preoptic Area; Pupil; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1986 |
Possible involvement of presynaptic alpha 1-adrenoceptors in the effects of idazoxan and prazosin on 3H-noradrenaline release from tail arteries of SHR.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Reversal by alpha-2 agonists of diazepam withdrawal hyperactivity in rats.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Diazepam; Guanfacine; Guanidines; Male; Motor Activity; Phenylacetates; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine | 1986 |
Effects of alpha 2-adrenergic agonists and antagonists on photoreceptor membrane currents.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Evoked Potentials, Visual; Light; Membrane Potentials; Photoreceptor Cells; Yohimbine | 1987 |
Pharmacological characterization of spinal alpha adrenoceptors related to blood pressure control in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain Stem; Clonidine; Dopamine; Guanabenz; Hydroxydopamines; Injections, Spinal; Male; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1987 |
Alpha 2-adrenergic receptor turnover in adipose tissue and kidney: irreversible blockade of alpha 2-adrenergic receptors by benextramine.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Clonidine; Cricetinae; Cystamine; Dose-Response Relationship, Drug; Kidney; Lipid Mobilization; Male; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine | 1986 |
The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dioxanes; Female; Idazoxan; Isoquinolines; Male; Medulla Oblongata; Piperazines; Prazosin; Yohimbine | 1987 |
Celiprolol, a compound possessing weak alpha 2-adrenergic antagonist properties in the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Catecholamines; Celiprolol; Clonidine; Coronary Circulation; Dogs; Heart Rate; In Vitro Techniques; Methoxamine; Propanolamines; Propranolol; Saphenous Vein; Vasoconstriction; Yohimbine | 1986 |
Pharmacological manipulations of alpha-adrenoceptors in the infant rat and effects on growth hormone secretion. Study of the underlying mechanisms of action.
Topics: Animals; Animals, Newborn; Clonidine; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Immune Sera; Male; Methoxamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Somatostatin; Yohimbine | 1987 |
Neurotransmitters in "the smoke reflex" in rabbits.
Topics: Amitriptyline; Animals; Atropine; Clonidine; Heart Rate; Neurotransmitter Agents; Nicotiana; Norepinephrine; Plants, Toxic; Rabbits; Reflex; Smoke; Yohimbine | 1987 |
Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Electric Stimulation; Enkephalin, Leucine; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1987 |
Effects of alpha 1- and alpha 2-adrenoceptor stimulation and blockade on plasma insulin levels in the mouse.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Female; Glucose; Insulin; Insulin Secretion; Mice; Phenylephrine; Prazosin; Radioimmunoassay; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Dimaprit; Gastric Acid; Gastric Mucosa; Indomethacin; Ligation; Male; Muscle Contraction; Norepinephrine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Reserpine; Stomach Ulcer; Stress, Physiological; Thiourea; Yohimbine | 1987 |
Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Arousal; Clonidine; Electroencephalography; Injections, Intraventricular; Locus Coeruleus; Male; Methoxamine; Microinjections; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1987 |
Depression of reticulo-ruminal motor functions through the stimulation of alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Cattle; Clonidine; Female; Imidazoles; Muscle Contraction; Reticulum; Rumen; Sheep; Tolazoline; Xylazine; Yohimbine | 1987 |
Mediation of separation distress by alpha 2-adrenergic mechanisms in a non-human primate.
Topics: Adrenergic alpha-Agonists; Animals; Anxiety, Separation; Clonidine; Imipramine; Male; Prazosin; Receptors, Adrenergic, alpha; Saimiri; Vocalization, Animal; Yohimbine | 1987 |
Alpha-2 receptors mediate an endogenous noradrenergic suppression of kindling development.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Kindling, Neurologic; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
[Quantified electroencephalogram: value in the evaluation of therapy of cerebral aging].
Topics: Almitrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Stimulants; Cerebral Cortex; Clonidine; Dementia; Drug Combinations; Drug Evaluation; Electroencephalography; Humans; Piperazines; Rats; Secologanin Tryptamine Alkaloids; Yohimbine | 1987 |
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1987 |
Ca2+ channel-blocking effect of the yohimbine derivatives, 14 beta-benzoyloxyyohimbine and 14 beta-pho-nitrobenzoyloxyyohimbine.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Calcium Chloride; Clonidine; Male; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasoconstriction; Yohimbine | 1987 |
Effects of DJ-7141, a new peripherally acting alpha-2 adrenoceptor agonist, on blood pressure and gastric acid output in rats: evidence for the heterogeneity of alpha-2 adrenoceptors in different organs.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Gastric Acid; Imidazoles; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Splanchnic Nerves; Yohimbine | 1987 |
Comparison of the butyrate effects on neurotransmitter receptors in neurohybrids NG108-15 and NCB-20 cells.
Topics: Animals; Butyrates; Cell Line; Cell Membrane; Clonidine; Cricetinae; Cycloheximide; Hybrid Cells; Mice; Neurotransmitter Agents; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Opioid; Sensory Receptor Cells; Yohimbine | 1987 |
Possible role of alpha-2-noradrenergic receptors in modulation of sexual behavior in female guinea pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Estradiol; Female; Guinea Pigs; Idazoxan; Methoxamine; Ovariectomy; Phenylephrine; Posture; Progesterone; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1987 |
Alpha-adrenergic inhibition of rat cerebellar Purkinje cells in vitro: a voltage-clamp study.
Topics: Adrenergic alpha-Agonists; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cerebellum; Clonidine; Electric Conductivity; Membrane Potentials; Phentolamine; Prazosin; Purkinje Cells; Rats; Tetrodotoxin; Yohimbine | 1987 |
Postsynaptic effects of alpha agonists on adrenoceptors of the reserpinized rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Drug Interactions; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reserpine; Vas Deferens; Yohimbine | 1987 |
Alpha-adrenergic receptor regulation of Ca2+/Mg2+-ATPase in brain synaptic membranes.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Cerebral Cortex; Clonidine; Kinetics; Neurotransmitter Agents; Phenylephrine; Rats; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1987 |
Effects of alpha 2-adrenergic agonists on carbachol-stimulated catecholamine synthesis in cultured bovine adrenal medullary cells.
Topics: 2-Hydroxyphenethylamine; Adrenal Medulla; Adrenergic alpha-Agonists; Animals; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Guanidines; Octopamine; Oxymetazoline; Phenylacetates; Tyrosine; Tyrosine 3-Monooxygenase; Yohimbine | 1987 |
Is there a role for renal alpha 2-adrenoceptors in the pathogenesis of hypertension?
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Gluconeogenesis; Guanfacine; Guanidines; Hypertension; In Vitro Techniques; Kidney; Methoxamine; Norepinephrine; Parathyroid Glands; Phenylacetates; Prazosin; Pyruvates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Vascular Resistance; Yohimbine | 1987 |
Central versus peripheral effect of clonidine on hepatic venous plasma glucose concentrations in fasted rats.
Topics: Animals; Blood Glucose; Clonidine; Fasting; Glucagon; Hepatic Veins; Injections, Intravenous; Injections, Intraventricular; Insulin; Kinetics; Male; Phentolamine; Rats; Rats, Inbred Strains; Somatostatin; Yohimbine | 1988 |
Postnatal treatment of rats with adrenergic receptor agonists or antagonists influences differentiation of sexual behavior.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Body Weight; Clonidine; Female; Male; Organ Size; Ovariectomy; Ovary; Posture; Prazosin; Rats; Rats, Inbred Strains; Sex Characteristics; Sexual Behavior, Animal; Testosterone; Yohimbine | 1987 |
Inhibition of glucose-stimulated insulin release by alpha 2-adrenoceptor activation is parallelled by both a repolarization and a reduction in cytoplasmic free Ca2+ concentration.
Topics: Adrenergic alpha-Agonists; Aminoquinolines; Animals; Calcium; Clonidine; Cytoplasm; Diazoxide; Female; Glucose; Insulin; Male; Membrane Potentials; Mice; Ouabain; Potassium; Yohimbine | 1988 |
Further evidence of noradrenergic regulation of rat hypothalamic estrogen receptor concentration: possible non-functional increase and functional decrease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cytosol; Dioxanes; Female; Hypothalamus; Idazoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Estrogen; Yohimbine | 1987 |
Alpha 2-adrenergic receptors in brown adipose tissue of infant rats--I. Identification and characteristics of binding sites in isolated plasma membranes.
Topics: Adipose Tissue, Brown; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Membrane; Clonidine; Dihydroalprenolol; Dioxanes; Idazoxan; Kinetics; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
The adrenergic agonist tizanidine has differential effects on flexor reflexes of intact and spinalized rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electromyography; Muscle Contraction; Prazosin; Reaction Time; Reflex; Spinal Cord; Yohimbine | 1987 |
A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood-Brain Barrier; Callitrichinae; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Gastrointestinal Motility; Male; Muscle Contraction; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1988 |
Blocking action of berberine on alpha 2- and alpha 1-adrenoceptors in rat vas deferens and anococcygeus muscle.
Topics: Adrenergic alpha-Antagonists; Anal Canal; Animals; Berberine; Berberine Alkaloids; Clonidine; Dose-Response Relationship, Drug; Male; Muscle, Smooth; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1987 |
Prejunctional alpha 2-adrenergic properties of S-3341 (dicyclopropylmethyl)amino-2-delta-2-oxazoline: a comparison with clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Oxazoles; Prazosin; Rats; Rats, Inbred WKY; Rilmenidine; Vas Deferens; Yohimbine | 1987 |
Blockade of alpha 2-adrenoceptors by 1-(2-pyrimidinyl)-piperazine (PmP) in vivo and its relation to the activity of buspirone.
Topics: Adrenergic alpha-Antagonists; Animals; Buspirone; Cerebral Cortex; Clonidine; Gastrointestinal Transit; Hypnotics and Sedatives; Male; Methoxyhydroxyphenylglycol; Rats; Reflex; Yohimbine | 1988 |
Alpha 2-antagonistic effect of N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON-954).
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Dopamine Antagonists; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Myenteric Plexus; Pentylenetetrazole; Rats; Seizures; Urea; Vas Deferens; Yohimbine | 1988 |
Precontraction-induced contractile response of isolated canine portal vein to alpha-2 adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcimycin; Cats; Clonidine; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Yohimbine | 1988 |
Behavioral evidence for the role of noradrenaline in putative anxiolytic and sedative effects of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Clonidine; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Male; Norepinephrine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Yohimbine | 1988 |
Presynaptic alpha 2-adrenoceptors mediate inhibition of cholinergic transmission in rabbit vesical parasympathetic ganglia.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; Ganglia, Parasympathetic; Idazoxan; Rabbits; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1987 |
Antagonism of clonidine-induced hypothermia by alpha adrenoceptor antagonists in electrically stimulated mice.
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Electroshock; Fever; Male; Mice; Mice, Inbred Strains; Phenoxybenzamine; Prazosin; Yeasts; Yohimbine | 1988 |
Tonic descending inhibition of the spinal cardio-sympathetic reflex in the cat.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Denervation; Differential Threshold; Electric Stimulation; Heart Conduction System; Nerve Block; Neural Conduction; Neural Inhibition; Neurons, Afferent; Pressoreceptors; Reflex; Spinal Cord; Sympathetic Nervous System; Yohimbine | 1988 |
Release of [3H]-noradrenaline from the sympathetic nerves to bovine mesenteric lymphatic vessels and its modification by alpha-agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cocaine; Electric Stimulation; Feedback; Lymphatic System; Mesentery; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Xylazine; Yohimbine | 1988 |
Selective alpha-2 adrenoceptor agonists alter fluid and electrolyte transport in mammalian small intestine.
Topics: 16,16-Dimethylprostaglandin E2; Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Intestine, Small; Male; Rabbits; Yohimbine | 1988 |
Enhanced vascular alpha-adrenergic neuroeffector system in diabetes: importance of calcium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; Guanabenz; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Stereoselective blockade of alpha-adrenoceptors by berbine derivatives.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Berberine Alkaloids; Binding, Competitive; Blood Pressure; Chemical Phenomena; Chemistry; Clonidine; Heart Rate; Ligands; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
[3H]L-654,284 as a probe of the central alpha 2 adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Cerebral Cortex; Clonidine; In Vitro Techniques; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Presynaptic alpha 2-adrenoceptor, opioid kappa-receptor and adenosine A1-receptor interactions on noradrenaline release in rabbit brain cortex.
Topics: Analgesics, Opioid; Animals; Cadmium; Cerebral Cortex; Clonidine; Cocaine; Cyclazocine; Drug Interactions; Electric Stimulation; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Norepinephrine; Phenylisopropyladenosine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Purinergic; Tetrodotoxin; Yohimbine | 1988 |
Alpha noradrenergic agonists promote catalepsy in the mouse.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Catalepsy; Clonidine; Isoproterenol; Mice; Models, Biological; Motor Activity; Phenoxybenzamine; Phenylephrine; Timolol; Yohimbine | 1988 |
No evidence for more than one type of alpha 1-adrenoreceptor in rabbit pulmonary artery.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Male; Methoxamine; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1988 |
Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice.
Topics: Animals; Behavior, Animal; Brain; Clonidine; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Piperazines; Substance Withdrawal Syndrome; Triazoles; Yohimbine | 1989 |
Effects of pertussis toxin on the behavioural and ECoG spectrum changes induced by clonidine and yohimbine after their microinfusion into the locus coeruleus.
Topics: Animals; Behavior, Animal; Clonidine; Electroencephalography; Infusions, Parenteral; Locus Coeruleus; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella; Yohimbine | 1989 |
Evidence of norepinephrine-mediated suppression of para-chlorophenylalanine-induced muricidal behavior.
Topics: Aggression; Animals; Clonidine; Electric Stimulation; Electrodes, Implanted; Fenclonine; Locus Coeruleus; Male; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Yohimbine | 1985 |
Biochemically stimulated release of atrial natriuretic factor from heart-lung preparation of Dahl rats.
Topics: Animals; Atrial Natriuretic Factor; Clonidine; Hemodynamics; Lung; Myocardium; Phenylephrine; Radioimmunoassay; Rats; Sodium Chloride; Yohimbine | 1988 |
Decrease of clonidine binding affinity to alpha 2-adrenoceptor by ADP-ribosylation of 41,000-dalton proteins in rat cerebral cortical membranes by islet-activating protein.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Toxins; Binding, Competitive; Cell Membrane; Cerebral Cortex; Clonidine; GTP-Binding Proteins; Guanosine Triphosphate; Male; Membrane Proteins; NAD; Nucleoside Diphosphate Sugars; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1985 |
Postjunctional alpha-1 and alpha-2 adrenoceptors in the coronaries of the perfused guinea-pig heart.
Topics: Animals; Azepines; Clonidine; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nordefrin; Norepinephrine; Perfusion; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1985 |
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Tolazoline; Yohimbine | 1985 |
Characterization of the alpha adrenergic receptor population in hippocampus up regulated by serotonergic raphe deafferentiation.
Topics: Animals; Clonidine; Dioxanes; Female; Guanylyl Imidodiphosphate; Hippocampus; Kinetics; Norepinephrine; Prazosin; Propranolol; Raphe Nuclei; Rats; Receptors, Adrenergic, alpha; Serotonin; Sodium; Yohimbine | 1985 |
Alpha 2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet. Evidence for a receptor reserve.
Topics: Adenylyl Cyclases; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Cyclic AMP; Epinephrine; Humans; Kinetics; Norepinephrine; Phenoxybenzamine; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Significant role of alpha 2-adrenoceptors in coronary artery spasm.
Topics: Animals; Clonidine; Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Dogs; Electrocardiography; Ergonovine; Female; Male; Methoxamine; Norepinephrine; Phentolamine; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1985 |
Epinephrine release and presynaptic alpha 2-adrenoceptic regulation in the guinea pig hypothalamus.
Topics: Animals; Clonidine; Epinephrine; Guinea Pigs; Hypothalamus; Receptors, Adrenergic, alpha; Synaptic Transmission; Yohimbine | 1985 |
beta-Adrenoceptor stimulation-induced increase in the number of alpha 2-adrenoceptors of cerebral cortical membranes in rats.
Topics: Animals; Cerebral Cortex; Cholera Toxin; Clonidine; Guanosine Triphosphate; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Synaptic Membranes; Yohimbine | 1985 |
Lesioning of serotoninergic and noradrenergic nerve fibres of the rat brain does not decrease binding of 3H-clonidine and 3H-rauwolscine to cortical membranes.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Fibers; Animals; Cerebral Cortex; Clonidine; Hydroxydopamines; In Vitro Techniques; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Tritium; Yohimbine | 1985 |
Studies on the mechanism of clonidine-induced mydriasis in the rat.
Topics: Animals; Brain; Clonidine; Electric Stimulation; Female; Iris; Male; Norepinephrine; Parasympathetic Nervous System; Pupil; Rats; Receptors, Adrenergic, alpha; Reflex; Yohimbine | 1985 |
Platelet alpha-2-adrenergic dysfunction in negative symptom schizophrenia: a preliminary study.
Topics: Blood Platelets; Chlorpromazine; Clonidine; Humans; Kinetics; Psychiatric Status Rating Scales; Receptors, Adrenergic, alpha; Schizophrenia; Schizophrenic Psychology; Yohimbine | 1985 |
Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors?
Topics: Animals; Arousal; Benzodiazepinones; Brain; Chlordiazepoxide; Clonidine; Dose-Response Relationship, Drug; Flumazenil; Male; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Social Behavior; Social Environment; Yohimbine | 1985 |
Characterization of platelet alpha 2 adrenoceptors and measurement in control and depressed subjects.
Topics: Adult; Aged; Blood Platelets; Clonidine; Depressive Disorder; Dihydroergotoxine; Epinephrine; Female; Humans; Male; Middle Aged; Physical Exertion; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1985 |
Lack of desensitization of alpha-2-mediated inhibition of lipolysis in fat cells after acute and chronic treatment with clonidine.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Clonidine; Cricetinae; Humans; In Vitro Techniques; Isoproterenol; Lipolysis; Nucleoside Deaminases; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Selective interaction of DG-5128 with a low agonist affinity state of alpha-2 adrenoceptor.
Topics: Animals; Cerebral Cortex; Clonidine; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT-receptor agonists.
Topics: Animals; Clonidine; Hippocampus; In Vitro Techniques; Maprotiline; Norepinephrine; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Serotonin; Yohimbine | 1985 |
Evidence for the modulation of sexual behavior by alpha-adrenoceptors in male rats.
Topics: Animals; Clonidine; Copulation; Drug Interactions; Ejaculation; Kinetics; Male; Prazosin; Rats; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1985 |
Clonidine-induced desensitization differentiates presynaptic alpha-2 adrenoceptors of the guinea-pig ileum and rat vas deferens.
Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Oxymetazoline; Rats; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1985 |
Clonidine and presynaptic adrenoceptor theory.
Topics: Animals; Clonidine; Drug Interactions; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Norepinephrine; Receptors, Adrenergic; Receptors, Neurotransmitter; Yohimbine | 1985 |
Yohimbine and clonidine recognize different states of adrenergic receptors on human platelets: reconsideration of studies on platelet alpha-2 receptors in depressive illness.
Topics: Blood Platelets; Clonidine; Depressive Disorder; Humans; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Postsynaptic alpha 2-noradrenergic receptors mediate feeding induced by paraventricular nucleus injection of norepinephrine and clonidine.
Topics: Animals; Clonidine; Injections; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tryptamines; Yohimbine | 1985 |
Postsynaptic alpha adrenoceptors in baboon cerebral and mesenteric arteries.
Topics: Animals; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Norepinephrine; Papio; Phentolamine; Phenylephrine; Potassium Chloride; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1985 |
Dual effects of clonidine on micturition reflex in urethane anesthetized rats.
Topics: Anesthesia; Animals; Clonidine; Electric Stimulation; Hydroxydopamines; Injections, Intraventricular; Male; Muscle Contraction; Oxidopamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sympathectomy, Chemical; Synaptic Transmission; Urethane; Urinary Bladder; Urination; Yohimbine | 1985 |
Epinephrine-stimulated maintained rubidium efflux from guinea pig hepatocytes may involve alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Calcium; Clonidine; Epinephrine; Guinea Pigs; In Vitro Techniques; Liver; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Rubidium; Yohimbine | 1985 |
Abnormality of alpha 1-adrenergic receptors in the frontal cortex of epileptic rats.
Topics: Animals; Carbachol; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Inferior Colliculi; Male; Norepinephrine; Phentolamine; Phosphatidylinositols; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine | 1986 |
N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin -2-yl)-N- methyl-2-hydroxyethane-sulfonamide: a potent and selective alpha 2-adrenoceptor antagonist.
Topics: Animals; Binding, Competitive; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Clonidine; Male; Prazosin; Pupil; Quinolizines; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Yohimbine | 1985 |
One-way generalization of clonidine to the discriminative stimulus produced by cocaine.
Topics: Animals; Clonidine; Cocaine; Discrimination, Psychological; Generalization, Stimulus; Male; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates.
Topics: Aging; Animals; Cerebral Cortex; Clonidine; Cognition; Female; Hydroxydopamines; Macaca mulatta; Memory; Oxidopamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Alpha adrenoceptor subtype mediating sympathetic mobilization of blood from the hepatic venous system in anesthetized cats.
Topics: Anesthesia; Animals; Blood Volume; Cats; Clonidine; Electric Stimulation; Hepatic Veins; Nordefrin; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1986 |
Large-scale purification of alpha 2-adrenergic receptor-enriched membranes from human platelets. Persistent association of guanine nucleotides with nonpurified membranes.
Topics: Adenylyl Cyclases; Blood Platelets; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Clonidine; Colforsin; Epinephrine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Norepinephrine; Receptors, Adrenergic, beta; Tritium; Yohimbine | 1986 |
p-Azidoclonidine: a photoaffinity label for the alpha 2-adrenoceptor.
Topics: Affinity Labels; Animals; Cerebral Cortex; Clonidine; Female; In Vitro Techniques; Kinetics; Membranes; Norepinephrine; Photochemistry; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1985 |
Involvement of guanine nucleotide and sodium in regulation of yohimbine and clonidine binding sites in the HT29 human colon adenocarcinoma cell-line.
Topics: Adenocarcinoma; Binding, Competitive; Cell Line; Clonidine; Colonic Neoplasms; Epinephrine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1985 |
Central adrenergic receptor control of renal function in conscious hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urodynamics; Yohimbine | 1986 |
Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission.
Topics: Afferent Pathways; Animals; Central Nervous System; Cerebral Cortex; Clonidine; gamma-Aminobutyric Acid; Hypothalamus; Ibotenic Acid; Methoxyhydroxyphenylglycol; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spinal Cord; Synaptic Transmission; Yohimbine | 1985 |
Islet-activating protein (pertussis toxin) diminishes alpha 2-adrenoceptor mediated effects on noradrenaline release.
Topics: Adenylate Cyclase Toxin; Animals; Clonidine; Cyclic AMP; Electric Stimulation; Hemagglutination Tests; Hippocampus; In Vitro Techniques; Norepinephrine; Pertussis Toxin; Rabbits; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1985 |
An endogenous brain substance, CDS (clonidine-displacing-substance), inhibits the twitch response of rat vas deferens.
Topics: Animals; Binding, Competitive; Brain Chemistry; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Imidazoline Receptors; Male; Muscle Contraction; Phentolamine; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine | 1986 |
Effect of clonidine on platelet alpha 2-adrenoreceptors and plasma norepinephrine of children with Tourette syndrome.
Topics: Blood Platelets; Child; Clonidine; Humans; Kinetics; Male; Norepinephrine; Radioligand Assay; Receptors, Adrenergic; Tourette Syndrome; Yohimbine | 1985 |
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Selective inhibition of responses of feline dorsal horn neurones to noxious cutaneous stimuli by tizanidine (DS103-282) and noradrenaline: involvement of alpha 2-adrenoceptors.
Topics: Animals; Cats; Clonidine; Female; Male; Neurons, Afferent; Norepinephrine; Pain; Receptors, Adrenergic, alpha; Sensation; Skin; Spinal Cord; Yohimbine | 1985 |
[Epinephrine uptake and release and presynaptic alpha 2-adrenoceptic regulation in the guinea pig hypothalamus].
Topics: Animals; Clonidine; Electric Stimulation; Epinephrine; Female; Guinea Pigs; Hypothalamus; In Vitro Techniques; Kinetics; Norepinephrine; Receptors, Adrenergic, alpha; Synaptic Transmission; Yohimbine | 1986 |
Isolated failure of autonomic noradrenergic neurotransmission. Evidence for impaired beta-hydroxylation of dopamine.
Topics: Adrenergic Fibers; Adult; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Dopamine; Female; Humans; Hydroxylation; Hypotension, Orthostatic; Norepinephrine; Synaptic Transmission; Tyramine; Yohimbine | 1986 |
Postsynaptic alpha 1- and alpha 2-adrenoceptors mediating the action of the sympathetic system on muscle spindles, in the rabbit.
Topics: Animals; Clonidine; Epinephrine; In Vitro Techniques; Male; Muscles; Neck Muscles; Norepinephrine; Phenoxybenzamine; Phenylephrine; Rats; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1986 |
[3H]clonidine and [3H]yohimbine binding to solubilized alpha 2-adrenoceptors from rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Cholic Acids; Clonidine; GTP-Binding Proteins; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Solubility; Yohimbine | 1986 |
Increased sympatho-adrenal tone and adrenal medulla reactivity in DOCA-salt hypertensive rats.
Topics: Adrenal Medulla; Animals; Carotid Arteries; Clonidine; Desoxycorticosterone; Epinephrine; Hypertension; Male; Nerve Fibers; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Chloride; Sympathetic Nervous System; Vagotomy; Vagus Nerve; Yohimbine | 1986 |
Effects of clonidine and yohimbine on plasma cyclic nucleotide levels in clonidine-naive and clonidine-treated mice.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Hexamethonium Compounds; Injections, Intraperitoneal; Male; Mice; Oxymetazoline; Propranolol; Time Factors; Yohimbine | 1986 |
Studies that question the existence of alpha-2 adrenoceptors in tail arteries of normotensive Sprague-Dawley rats.
Topics: Animals; Arteries; Azepines; Clonidine; Dose-Response Relationship, Drug; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tail; Vasoconstriction; Yohimbine | 1986 |
Long-term amitriptyline treatment alters the affinity state of alpha 2 adrenoceptors in rabbit hindbrain.
Topics: Amitriptyline; Animals; Blood Pressure; Body Weight; Brain Stem; Cerebellum; Clonidine; Dioxanes; Epinephrine; Heart Rate; Idazoxan; Male; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
3H-clonidine and 3H-yohimbine binding to glass fiber filters: implications for studies with platelet membranes.
Topics: Binding Sites; Blood Platelets; Cell Membrane; Chemical Phenomena; Chemistry; Clonidine; Filtration; Glass; Humans; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Evidence for alpha adrenoceptor modulation of the nociceptive jaw-opening reflex in rats and rabbits.
Topics: Analgesia; Animals; Clonidine; Dental Pulp; Electromyography; Jaw; Male; Pain; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Yohimbine | 1986 |
Decreased alpha 2-adrenergic receptors on platelet membranes from diabetic patients with autonomic neuropathy and orthostatic hypotension.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Platelets; Catecholamines; Clonidine; Diabetic Neuropathies; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Receptors, Adrenergic, alpha; Renin; Yohimbine | 1986 |
Involvement of postsynaptic alpha 1- and alpha 2-adrenoceptors in the flexor reflex activity in the spinal rats.
Topics: Animals; Clonidine; Clozapine; Decerebrate State; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Spinal Cord; Yohimbine | 1986 |
N-ethylmaleimide (NEM) diminishes alpha 2-adrenoceptor mediated effects on noradrenaline release.
Topics: Animals; Biological Transport; Clonidine; Electric Stimulation; Ethylmaleimide; Female; Hippocampus; Limbic System; Male; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha; Time Factors; Tritium; Yohimbine | 1986 |
Studies on epinephrine-induced lung edema in the rat. I. Selective alpha 1-adrenoceptor involvement.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Dibenzylchlorethamine; Epinephrine; Female; Metaraminol; Norepinephrine; Phenylephrine; Practolol; Prazosin; Propranolol; Pulmonary Edema; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Pharmacologic evidence that high dose chronic amitriptyline and desipramine down-regulate alpha 2-receptor-mediated hypothermia in the rat.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Half-Life; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Occurrence of alpha 2-adrenergic effects on adenylate cyclase activity and (3H)-clonidine specific binding in brown adipose tissue from foetal rats.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Clonidine; Dose-Response Relationship, Drug; Isoproterenol; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Receptor protection experiments confirm the identity of presynaptic alpha 2-autoreceptors.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1986 |
Alpha 2-receptor control over release of noradrenaline in rat thalamus.
Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; In Vitro Techniques; Male; Norepinephrine; Potassium; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Thalamus; Yohimbine | 1986 |
Central alpha 2-adrenergic control of the pattern of small intestinal motility in rats.
Topics: Animals; Clonidine; Duodenum; Eating; Electromyography; Fasting; Gastrointestinal Motility; Jejunum; Male; Naphazoline; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Mutual interaction between presynaptic alpha 2-adrenoceptors and opioid kappa-receptors at the noradrenergic axons of rabbit brain cortex.
Topics: Animals; Axons; Cerebral Cortex; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; Male; Naloxone; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1986 |
Adrenergic influences on sexual differentiation of the rat brain.
Topics: Animals; Brain; Clonidine; Feedback; Female; Posture; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sex Differentiation; Sexual Behavior, Animal; Testosterone; Yohimbine | 1986 |
Alpha-2-adrenergic control of prolactin release.
Topics: Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Male; Piperoxan; Pregnancy; Prolactin; Quinolizines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Alpha adrenergic receptors mediate angiotensin-induced prostaglandin production in the rabbit isolated vas deferens.
Topics: Angiotensin II; Angiotensin III; Animals; Clonidine; Male; Muscle Contraction; Phenylephrine; Prazosin; Prostaglandins E; Rabbits; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1987 |
A study on the antagonism of the intestinal inhibitory effects of morphine and clonidine by yohimbine in mice.
Topics: Animals; Clonidine; Female; Gastrointestinal Motility; Mice; Mice, Inbred ICR; Morphine; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Postjunctional vascular smooth muscle alpha-2 adrenoreceptors in human autonomic failure.
Topics: Aged; Autonomic Nervous System Diseases; Blood Platelets; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Muscle, Smooth; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Platelet radioligand binding and neuroendocrine challenge tests in depression.
Topics: Adult; Binding Sites; Blood Platelets; Blood Pressure; Clonidine; Depression; Female; Growth Hormone; Heart Rate; Humans; Imipramine; Male; Middle Aged; Radioligand Assay; Receptors, Adrenergic, alpha; Serotonin; Yohimbine | 1986 |
Evidence for the involvement of alpha-2 adrenoceptors in the sedation but not REM sleep inhibition by clonidine in the rat.
Topics: Animals; Clonidine; Electroencephalography; Hypnotics and Sedatives; Male; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep, REM; Yohimbine | 1986 |
Effect of the amino-oxazoline derivative S-3341 on pre- and postjunctional alpha-adrenoceptors in isolated blood vessels.
Topics: Animals; Clonidine; Dogs; In Vitro Techniques; Norepinephrine; Oxazoles; Perfusion; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Saphenous Vein; Vasoconstriction; Yohimbine | 1986 |
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line. Alpha 2-adrenergic agonists counteract effect of vasoactive intestinal peptide.
Topics: Adenocarcinoma; Brimonidine Tartrate; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Epinephrine; Fructosediphosphates; Hexosediphosphates; Humans; Quinoxalines; Vasoactive Intestinal Peptide; Yohimbine | 1986 |
Response of supraoptic magnocellular neurons to stimulation of forebrain alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Carotid Artery, Internal; Clonidine; Evoked Potentials; Infusions, Intra-Arterial; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Supraoptic Nucleus; Vasopressins; Yohimbine | 1986 |
Quantitative evaluation of alpha- and beta-adrenoceptor modulation of [3H]choline release in guinea pig superior cervical ganglia.
Topics: Acetylcholine; Animals; Choline; Clonidine; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1987 |
Lisuride-induced mounting and its modification by drugs active on adrenergic and dopaminergic receptors.
Topics: Animals; Clonidine; Ergolines; Imidazoles; Lisuride; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sexual Behavior, Animal; Yohimbine | 1986 |
Noradrenergic regulation of cytosol estrogen receptors in female rat hypothalamus: possible role of alpha 2-noradrenergic receptors.
Topics: Animals; Cell Nucleus; Clonidine; Cytosol; Female; Hypothalamus; Norepinephrine; Osmolar Concentration; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Estrogen; Yohimbine | 1987 |
Are the alpha 2-adrenoceptors in the noradrenaline cell body region of physiological significance?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Clonidine; Dopamine; Ganglia, Spinal; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salivary Glands; Sympathetic Nervous System; Yohimbine | 1987 |
Postjunctional alpha 2-adrenoceptors in pial arteries of anesthetized newborn pigs.
Topics: Animals; Animals, Newborn; Cerebral Arteries; Clonidine; Female; Ganglia, Sympathetic; Male; Phenylephrine; Pia Mater; Prazosin; Receptors, Adrenergic, alpha; Swine; Vasoconstriction; Yohimbine | 1987 |
Changes in catecholamine-induced lipolysis in isolated human fat cells during the first year of life.
Topics: Adenosine Deaminase; Adipose Tissue; Adolescent; Adult; Age Factors; Catecholamines; Clonidine; Drug Interactions; Epinephrine; Female; Glucose; Humans; Infant; Infant, Newborn; Isoproterenol; Lipolysis; Male; Microbial Collagenase; Middle Aged; Norepinephrine; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Effects of antidepressant drug treatments on alpha 2-adrenoceptor control of [3H]noradrenaline release from hypothalamic synaptosomes.
Topics: Animals; Antidepressive Agents; Clonidine; Clorgyline; Desipramine; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1987 |
Plasma immunoreactive atrial natriuretic factor is inhibited by selective blockade of alpha 2-adrenergic receptors in conscious Sprague-Dawley rats.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Clonidine; Drug Interactions; Female; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Verapamil; Yohimbine | 1987 |
Alpha 2-adrenergic potentiation of adenosine-stimulating effect on glucagon secretion.
Topics: Adenosine; Animals; Clonidine; Drug Synergism; Epinephrine; Glucagon; Male; Pancreas; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
The release of catecholamines from the adrenal medulla and its modulation by alpha 2-adrenoceptors in the anaesthetized dog.
Topics: Adrenal Medulla; Animals; Catecholamines; Clonidine; Dioxanes; Dogs; Dopamine; Electric Stimulation; Epinephrine; Female; Idazoxan; Male; Norepinephrine; Oxymetazoline; Receptors, Adrenergic, alpha; Splanchnic Nerves; Yohimbine | 1987 |
On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain; Clonidine; Endorphins; Heart Rate; Hypertension; Hypothalamus; Male; Naloxone; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1987 |
Alpha 2-adrenoceptor modulation of nociception in rat spinal cord: location, effects and interactions with morphine.
Topics: Animals; Autoradiography; Clonidine; Dihydromorphine; Drug Interactions; Electrophysiology; In Vitro Techniques; Injections, Spinal; Male; Morphine; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1987 |
Phentolamine, a deceptive tool to investigate sympathetic nervous control of insulin release.
Topics: Animals; Clonidine; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Phentolamine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tolbutamide; Yohimbine | 1988 |
Clonidine--induced behavioural despair in mice: reversal by antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Azepines; Clonidine; Depression; Diazepam; Guanfacine; Guanidines; Lithium; Male; Phenylacetates; Rats; Rats, Inbred Strains; Tranylcypromine; Yohimbine | 1986 |
Neuronal source of plasma dihydroxyphenylalanine.
Topics: Adolescent; Adrenalectomy; Adrenergic Fibers; Adult; Aged; alpha-Methyltyrosine; Anesthesia; Animals; Catecholamines; Clonidine; Diazepam; Dihydroxyphenylalanine; Dogs; Female; Humans; Isoproterenol; Macaca fascicularis; Male; Methyltyrosines; Middle Aged; Sympathectomy; Trimethaphan; Yohimbine | 1987 |
A submucosal mechanism for catecholamine-induced increases in fluid absorption in rabbit ileum in vitro.
Topics: Animals; Carbachol; Clonidine; Dopamine; Electric Conductivity; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Mannitol; Norepinephrine; Rabbits; Theophylline; Water; Yohimbine | 1988 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Penis; Phenylephrine; Practolol; Prazosin; Prenalterol; Procaterol; Receptors, Adrenergic; Receptors, Muscarinic; Yohimbine | 1985 |
Serotonin-induced contraction of canine saphenous vein: mediation by 5-HT1 receptors.
Topics: Animals; Clonidine; Dogs; Drug Interactions; Emetics; In Vitro Techniques; Ketanserin; Mianserin; Muscle Contraction; Naphthols; Piperidines; Receptors, Serotonin; Saphenous Vein; Serotonin; Yohimbine | 1985 |
Peripheral analgesic action of clonidine: mediation by release of endogenous enkephalin-like substances.
Topics: Analgesics; Animals; Carrageenan; Clonidine; Dinoprostone; Drug Tolerance; Enkephalins; Male; Morphine; Naloxone; Peripheral Nerves; Prostaglandins E; Rats; Rats, Inbred Strains; Yohimbine | 1988 |
Evoked secretion of [3H]noradrenaline and ATP from nerve varicosities isolated from the myenteric plexus of the guinea pig ileum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Myenteric Plexus; Nicotine; Norepinephrine; Potassium; Veratridine; Yohimbine | 1988 |
Effects of clonidine and yohimbine on a C-fibre-evoked blood pressure reflex in the rat.
Topics: Animals; Blood Pressure; Capsaicin; Cisterna Magna; Clonidine; Female; Injections; Injections, Spinal; Male; Nerve Fibers; Rats; Rats, Inbred Strains; Reflex; Yohimbine | 1988 |
Clonidine activates a cholinergic hippocampal theta rhythm in the rat.
Topics: Animals; Clonidine; Electroencephalography; Hippocampus; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Theta Rhythm; Yohimbine | 1988 |
Pertussis toxin inhibits the behavioural and ECoG effects induced by clonidine and yohimbine after their microinfusion into the locus coeruleus.
Topics: Animals; Cerebral Cortex; Clonidine; Electroencephalography; Locus Coeruleus; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Sleep; Virulence Factors, Bordetella; Yohimbine | 1988 |
A differential effect of yohimbine on adrenal and neuronal catecholamine release during bilateral carotid occlusion in the dog.
Topics: Adrenal Glands; Animals; Arterial Occlusive Diseases; Blood Pressure; Carotid Arteries; Catecholamines; Clonidine; Dogs; Heart Rate; Kidney; Male; Norepinephrine; Vagotomy; Yohimbine | 1988 |
Differential cardiovascular effects of central clonidine and B-HT 920 in conscious rats.
Topics: Animals; Azepines; Blood Pressure; Cardiovascular System; Clonidine; Epinephrine; Heart; Injections, Intraventricular; Male; Norepinephrine; Rats; Yohimbine | 1988 |
Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: pharmacological and behavioral studies.
Topics: Animals; Clonidine; Desipramine; Hippocampus; Male; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Yohimbine | 1988 |
Effects of sophoramine, an alkaloid from Sophora alopecuroides on isolated dog blood vessels.
Topics: Adrenergic Fibers; Alkaloids; Animals; Cerebral Arteries; Clonidine; Coronary Vessels; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Vasodilator Agents; Yohimbine | 1988 |
[Inhibitory effect of clonidine on gastrointestinal motility].
Topics: Animals; Clonidine; Defecation; Depression, Chemical; Female; Gastrointestinal Motility; Male; Mice; Rats; Yohimbine | 1988 |
Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans.
Topics: Administration, Oral; Adult; Body Fluids; Clonidine; Desipramine; Female; Glycols; Humans; Infusions, Intravenous; Intracellular Fluid; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Supination; Yohimbine | 1988 |
Local suppressive effect of clonidine on penile erection in the dog.
Topics: Animals; Clonidine; Depression, Chemical; Dogs; Erectile Dysfunction; Male; Penile Erection; Penis; Regional Blood Flow; Yohimbine | 1988 |
Intrathecal morphine and clonidine: antinociceptive tolerance and cross-tolerance and effects on blood pressure.
Topics: Animals; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Tolerance; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Yohimbine | 1988 |
Clonidine inhibits electrodermal responses by an action on the spinal cord.
Topics: Animals; Cats; Clonidine; Dimethylphenylpiperazinium Iodide; Female; Galvanic Skin Response; Ganglia, Sympathetic; Injections, Intra-Arterial; Injections, Intravenous; Injections, Spinal; Male; Spinal Cord; Yohimbine | 1988 |
Pharmacological nature of newer imidazoli(di)nes on rat anococcygeus muscle.
Topics: Animals; Clonidine; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1988 |
Evidence for a spinal site of action of clonidine on somatic and viscerosomatic reflex activity evoked on the pudendal nerve in cats.
Topics: Action Potentials; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Female; Male; Prazosin; Reflex; Spinal Cord; Urethra; Urinary Bladder; Yohimbine | 1988 |
The effects of clonidine and yohimbine on locomotion and cutaneous reflexes in the adult chronic spinal cat.
Topics: Animals; Cats; Clonidine; Decerebrate State; Electromyography; Gait; Locomotion; Reflex; Skin; Skin Physiological Phenomena; Yohimbine | 1987 |
Putative site(s) and mechanism(s) of action of flupirtine, a novel analgesic compound.
Topics: Aminopyridines; Analgesics; Animals; Clonidine; Drug Evaluation, Preclinical; Efferent Pathways; Electroencephalography; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Reserpine; Yohimbine | 1987 |
Age-related variation of EEG responses to clonidine, prazosin and yohimbine in rats.
Topics: Aging; Animals; Brain; Clonidine; Electroencephalography; Electrophysiology; Prazosin; Rats; Yohimbine | 1987 |
Reciprocal potentiation of a vasoconstrictor response between 5-hydroxytryptamine and clonidine in the perfused mesenteric vascular bed of the rat.
Topics: Animals; Blood Pressure; Clonidine; Dinoprost; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Ouabain; Phenylephrine; Prostaglandins F; Rats; Rats, Inbred Strains; Serotonin; Splanchnic Circulation; Vasoconstriction; Yohimbine | 1987 |
Antiulcer activity of clonidine: lack of effect on gastric prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Clonidine; Dinoprostone; Female; Gastric Mucosa; Indomethacin; Prostaglandins E; Rats; Stomach Ulcer; Yohimbine | 1987 |
Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system.
Topics: Alkaloids; Animals; Clonidine; Cyproheptadine; Fluoxetine; Harmine; Male; Mice; Quipazine; Serotonin; Tremor; Yohimbine | 1986 |
Plasma norepinephrine concentration reflects pharmacological alteration of sympathetic activity in the conscious cat.
Topics: Animals; Cats; Chlorisondamine; Clonidine; Epinephrine; Hemodynamics; Hydralazine; Norepinephrine; Renin; Sympathetic Nervous System; Yohimbine | 1986 |
Yohimbine reduces morphine tolerance in guinea-pig ileum.
Topics: Animals; Clonidine; Drug Tolerance; Female; Guanfacine; Guanidines; Guinea Pigs; Ileum; Male; Morphine; Muscle, Smooth; Phenylacetates; Yohimbine | 1987 |
Behavioral effects of intrahippocampal injections of clonidine, yohimbine and salbutamol in the rat.
Topics: Albuterol; Animals; Clonidine; Hippocampus; Injections; Male; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Yohimbine | 1987 |
Hypothalamic monoamines and their catabolites in relation to the estradiol-induced luteinizing hormone surge.
Topics: Animals; Biogenic Amines; Chromatography, High Pressure Liquid; Clonidine; Estradiol; Female; Hypothalamo-Hypophyseal System; Hypothalamus; Luteinizing Hormone; Ovariectomy; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Quantitative determination of the effects of catecholaminergic agonists and antagonists on the rewarding efficacy of brain stimulation.
Topics: Amphetamine; Animals; Brain; Catecholamines; Clonidine; Drug Interactions; Electric Stimulation; Male; Molindone; Pimozide; Rats; Reward; Self Stimulation; Yohimbine | 1987 |
Effects of splanchnic nerve stimulation and of clonidine on gastric and duodenal HCO3- secretion in the anaesthetized cat.
Topics: Animals; Bicarbonates; Cats; Clonidine; Duodenum; Electric Stimulation; Female; Gastric Acid; Gastrointestinal Motility; Intestinal Secretions; Male; Prazosin; Splanchnic Nerves; Vagus Nerve; Yohimbine | 1987 |
[Effects of clonidine on the levels of cyclic nucleotides in rat brain regions: the change in cyclic nucleotides after clonidine alone or in combination with alpha-antagonists].
Topics: Animals; Blood Pressure; Brain Chemistry; Clonidine; Drug Interactions; Heart Rate; Male; Nucleotides, Cyclic; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Effect of ganglion blockade on cerebrospinal fluid norepinephrine.
Topics: Animals; Blood Pressure; Clonidine; Dogs; Male; Nitroprusside; Norepinephrine; Phenylephrine; Sympathetic Nervous System; Trimethaphan; Yohimbine | 1987 |
Central mechanisms of ethanol-induced adrenocortical response in selectively bred lines of mice.
Topics: Alcohol Deterrents; Animals; Carbachol; Clonidine; Corticosterone; Ethanol; Halothane; Male; Mice; Phentolamine; Propranolol; Yohimbine | 1987 |
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred F344; Tremor; Yohimbine | 1987 |
[Sexual dimorphism in the pressor response to l-adrenaline in rats].
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Epinephrine; Female; Gonadal Steroid Hormones; Male; Orchiectomy; Ovariectomy; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sex Factors; Yohimbine | 1986 |
Effect of tizanidine on body temperature in the mouse.
Topics: Animals; Body Temperature; Clonidine; Male; Mice; Mice, Inbred Strains; Yohimbine | 1986 |
Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypertension; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Propranolol; Rats; Tachycardia; Yohimbine | 1986 |
Cardiovascular effects of perfusion of the rostral rat hypothalamus with clonidine: differential interactions with prazosin and yohimbine.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemodynamics; Hypothalamus; Male; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Evidence that endogenous catecholamines can regulate acetylcholine release in a sympathetic ganglion.
Topics: Acetylcholine; Animals; Cats; Clonidine; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Norepinephrine; Phentolamine; Prazosin; Yohimbine | 1986 |
Use of alpha 2 adrenoreceptor agonists and antagonists in the functional assessment of the sympathetic nervous system.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Norepinephrine; Shy-Drager Syndrome; Sympathetic Nervous System; Yohimbine | 1986 |
Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level.
Topics: Animals; Apomorphine; Atropine; Bicuculline; Clonidine; Corticosterone; Dexamethasone; Diazepam; Drug Interactions; Female; Haloperidol; Picrotoxin; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Interactions between the effects of yohimbine, clonidine and [Ca]o on the electrical response of the mouse vas deferens.
Topics: Action Potentials; Animals; Calcium; Clonidine; Evoked Potentials; Male; Mice; Mice, Inbred C57BL; Neuromuscular Junction; Vas Deferens; Yohimbine | 1986 |
Substantia nigra and entopeduncular nucleus: supraspinal sites of the muscle relaxant action of tizanidine.
Topics: Animals; Basal Ganglia; Clonidine; Electromyography; Muscle Relaxants, Central; Muscle Tonus; Rats; Rats, Inbred Strains; Substantia Nigra; Yohimbine | 1986 |
Quantitation of total MHPG in the rat brain using a non enzymatic hydrolysis procedure. Effects of drugs.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Clonidine; Glycols; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Yohimbine potentiates the anticataleptic action of clonidine against perphenazine-induced catalepsy in rats.
Topics: Animals; Catalepsy; Clonidine; Drug Synergism; Male; Perphenazine; Quipazine; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Potentiation of clonidine analgesia by amitriptyline.
Topics: Amitriptyline; Analgesia; Animals; Clonidine; Drug Synergism; Male; Mice; Naloxone; Yohimbine | 1986 |
Behavioral and electrocortical effects of tolonidine in rats.
Topics: Animals; Behavior, Animal; Body Temperature; Clonidine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Phentolamine; Rats; Sleep; Yohimbine | 1986 |
The significance of adrenaline-induced potentiation of electrogenic sodium pumping in bullfrog sympathetic ganglia.
Topics: Animals; Clonidine; Epinephrine; Ganglia, Sympathetic; Kinetics; Methoxamine; Ouabain; Potassium; Prazosin; Propranolol; Rana catesbeiana; Sodium; Sucrose; Yohimbine | 1985 |
Role of endothelium in the contractions induced by norepinephrine and clonidine in rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Clonidine; Endothelium; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Potassium; Prazosin; Quinacrine; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Vasodilator Agents; Yohimbine | 1985 |
Effects of morphine on sprouting of locus coeruleus fibers in the neonatal rat.
Topics: Adrenergic Fibers; Animals; Animals, Newborn; Clonidine; Drug Interactions; Female; Hydroxydopamines; Locus Coeruleus; Male; Morphine; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Regeneration; Yohimbine | 1985 |
Stimulation of 3H-norepinephrine release by trifluoperazine from rat pineal glands.
Topics: Animals; Calcium; Clonidine; Dose-Response Relationship, Drug; Imipramine; In Vitro Techniques; Male; Norepinephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trifluoperazine; Yohimbine | 1986 |
Presynaptic effect of clonidine on unmyelinated afferent fibers in the spinal cord of the cat.
Topics: Action Potentials; Animals; Cats; Clonidine; Injections, Intravenous; Nerve Fibers; Neurons, Afferent; Phentolamine; Reaction Time; Spinal Cord; Synapses; Yohimbine | 1986 |
Discriminative stimuli produced by clonidine in spontaneously hypertensive rats: generalization to antihypertensive drugs with different mechanisms of action.
Topics: Animals; Antihypertensive Agents; Clonidine; Discrimination Learning; Dose-Response Relationship, Drug; Hypertension; Male; Rats; Rats, Inbred SHR; Sulpiride; Time Factors; Yohimbine | 1985 |
Adrenergic and non-adrenergic contraction of isolated urethral muscle from rabbit and man.
Topics: Adrenergic Fibers; Animals; Clonidine; Electric Stimulation; Female; Humans; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Parasympathetic Nervous System; Rabbits; Scopolamine; Sympathectomy, Chemical; Urethra; Yohimbine | 1985 |
Effects of clonidine on neuronal firing evoked by a noxious stimulus.
Topics: Animals; Clonidine; Electrophysiology; Isoquinolines; Male; Neurons; Norepinephrine; Pain; Physical Stimulation; Piperazines; Piperoxan; Rats; Rats, Inbred Strains; Stimulation, Chemical; Yohimbine | 1985 |
Noradrenergic modulation of sensorimotor processes in intact rats: the masseteric reflex as a model system.
Topics: Animals; Clonidine; Levodopa; Male; Masseter Muscle; Masticatory Muscles; Norepinephrine; Rats; Rats, Inbred Strains; Reflex; Yohimbine | 1985 |
Effects of clonidine and yohimbine on the social play of juvenile rats.
Topics: Animals; Clonidine; Drug Interactions; Female; Male; Play and Playthings; Rats; Social Behavior; Yohimbine | 1985 |
Biochemical correlates of morphine withdrawal. 2. Effects of clonidine.
Topics: Adrenal Glands; Animals; Clonidine; Denervation; Dose-Response Relationship, Drug; Epinephrine; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine | 1985 |
Behavioural pharmacology of imidazole, a potential antidepressant agent.
Topics: Aggression; Animals; Antidepressive Agents; Apomorphine; Azepines; Behavior, Animal; Body Temperature; Chickens; Clonidine; Drug Synergism; Imidazoles; Lethal Dose 50; Male; Mice; Motor Activity; Penile Erection; Rats; Rats, Inbred Strains; Sleep; Yohimbine | 1985 |
The functional importance of cerebral noradrenergic processes for the activating action of nootropic drugs in the behavioural despair test in mice.
Topics: Animals; Behavior, Animal; Brain; Clonidine; Dextroamphetamine; Immobilization; Male; Mice; Norepinephrine; Prazosin; Yohimbine | 1985 |
The analgesic activity of a clonidine analog. The formamidine, U-47,476A.
Topics: Amidines; Analgesics; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypnotics and Sedatives; Mice; Motor Activity; Naloxone; Phentolamine; Rats; Rats, Inbred Strains; Reaction Time; Reserpine; Species Specificity; Time Factors; Yohimbine | 1985 |
Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Circulation; Blood Pressure; Cats; Cisterna Magna; Clonidine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart; Heart Rate; Hypertension; Male; Splanchnic Nerves; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Vertebral Artery; Yohimbine | 1973 |
A further attempt to characterize sedative receptors activated by clonidine in chickens and mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Chickens; Chloral Hydrate; Clonidine; Female; Hypnotics and Sedatives; Isoproterenol; Mice; Moxisylyte; Pindolol; Receptors, Drug; Reflex; Sleep; Yohimbine | 1973 |
Effects of clonidine and some alpha-adrenoreceptor blocking agents on avoidance conditioned reflexes in rats: their interactions and antagonism by atropine.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Avoidance Learning; Clonidine; Conditioning, Classical; Depression, Chemical; Dibenzylchlorethamine; Male; Phenoxybenzamine; Phentolamine; Rats; Time Factors; Tolazoline; Yohimbine | 1974 |
Possible involvement of central adrenaline neurons in vasomotor and respiratory control. Studies with clonidine and its interactions with piperoxane and yohimbine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Cerebral Cortex; Clonidine; Dioxins; Epinephrine; Heart Rate; Male; Methyltyrosines; Neurons; Norepinephrine; Piperidines; Rats; Receptors, Adrenergic; Reflex; Respiration; Respiratory Center; Time Factors; Vasomotor System; Yohimbine | 1974 |
An investigation on the behavioral and hypothermic effects of yohimbine: interaction with drugs affecting central and peripheral monoamines.
Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Benserazide; Biogenic Amines; Body Temperature; Catecholamines; Chlorisondamine; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Haloperidol; Humans; Lysergic Acid Diethylamide; Male; Methysergide; Motor Activity; Pargyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Stereotyped Behavior; Yohimbine | 1974 |
Effects of clonidine and L-dopa on spontaneous and evoked splanchnic nerve discharges.
Topics: Animals; Blood Pressure; Carbidopa; Cats; Clonidine; Dihydroxyphenylalanine; Electric Stimulation; Evoked Potentials; Female; Heart Rate; Hypothalamus; Laminectomy; Male; Medulla Oblongata; Norepinephrine; Pressoreceptors; Receptors, Adrenergic; Sciatic Nerve; Spinal Cord; Splanchnic Nerves; Stereotaxic Techniques; Sympatholytics; Yohimbine | 1973 |
New evidence for an -andrenergic component in the sympathetic centres: centrally mediated decrease in sympathetic tone by L-dopa and its antagonism by piperoxane and yohimbine.
Topics: Animals; Blood Pressure; Cats; Clonidine; Dihydroxyphenylalanine; Drug Antagonism; Electric Stimulation; Female; Heart Rate; Male; Receptors, Adrenergic; Splanchnic Nerves; Sympathetic Nervous System; Sympatholytics; Yohimbine | 1972 |
Sympathetic nervous system in essential hypertension and antihypertensive response to alpha 2-adrenoceptor stimulation.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Clonidine; Humans; Hypertension; Norepinephrine; Prazosin; Regional Blood Flow; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs: comparison of phenylephrine, clonidine, and guanabenz.
Topics: Animals; Calcium; Clonidine; Denervation; Dogs; Drug Interactions; Female; Guanabenz; Guanidines; Kidney; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Alpha-2 adrenoceptors modulate [3H]dopamine release from rabbit retina.
Topics: Animals; Calcium; Clonidine; Dopamine; Electric Stimulation; Epinephrine; Nomifensine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Retina; Yohimbine | 1984 |
Interplay of alpha-2 and beta adrenoceptors in the control of free fatty acid release from bone marrow adipose tissue.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Bone Marrow; Clonidine; Dogs; Epinephrine; Fatty Acids, Nonesterified; Isoproterenol; Perfusion; Phentolamine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Theophylline; Yohimbine | 1984 |
Platelet alpha 2-adrenergic receptors in schizophrenic patients before and after phenothiazine treatment.
Topics: Adult; Blood Platelets; Chlorpromazine; Chronic Disease; Clonidine; Humans; Kinetics; Male; Norepinephrine; Receptors, Adrenergic; Schizophrenia; Yohimbine | 1984 |
[Effects of clonidine and yohimbine on semicarbazide-induced convulsion and electroconvulsive shock].
Topics: Animals; Clonidine; Electroshock; Female; Hydroxydopamines; Male; Mice; Oxidopamine; Propranolol; Receptors, Adrenergic, alpha; Seizures; Semicarbazides; Yohimbine | 1984 |
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.
Topics: Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imidazoles; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Tyramine; Yohimbine | 1984 |
Changes in the effects of clonidine on left atrium and hindlimb vasculature of rats in various thyroid states. A study of the responsiveness of alpha 2-adrenoceptors in the cardiovascular system.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Heart Atria; Hindlimb; Hypothyroidism; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Phentolamine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Thyroid Gland; Vasoconstriction; Yohimbine | 1984 |
Clonidine and yohimbine separate the sedation and the ptosis caused by cholecystokinin octapeptide and ceruletide.
Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ceruletide; Clonidine; Drug Antagonism; Haloperidol; Humans; Hypnotics and Sedatives; Male; Mice; Motor Activity; Sincalide; Yohimbine | 1984 |
Presence of presynaptic inhibitory alpha 1-adrenoceptors in the cardiac sympathetic nerves of the dog: effects of prazosin and yohimbine on sympathetic neurotransmission to the heart.
Topics: Animals; Clonidine; Dogs; Female; Heart Rate; Male; Methoxamine; Myocardium; Norepinephrine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Stellate Ganglion; Sympathetic Nervous System; Synaptic Transmission; Tachycardia; Yohimbine | 1984 |
Effect of pertussis toxin on the adrenergic regulation of plasma renin activity.
Topics: Adrenal Glands; Animals; Bacterial Toxins; Bordetella pertussis; Clonidine; Epinephrine; Isoproterenol; Kinetics; Male; Pertussis Toxin; Propranolol; Rats; Rats, Inbred Strains; Renin; Virulence Factors, Bordetella; Yohimbine | 1984 |
Effects of raubasine stereoisomers on pre- and postsynaptic alpha-adrenoceptors in the rat vas deferens.
Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Secologanin Tryptamine Alkaloids; Stereoisomerism; Vas Deferens; Yohimbine | 1984 |
Isolation and partial purification of a clonidine-displacing endogenous brain substance.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cattle; Chromatography; Clonidine; Electrophoresis, Agar Gel; Erythrocytes; Humans; Imidazoline Receptors; In Vitro Techniques; Iodocyanopindolol; Molecular Weight; Pindolol; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Turkeys; Yohimbine | 1984 |
Effect of intracerebroventricular clonidine on serum corticosterone levels in rats.
Topics: Adrenocorticotropic Hormone; alpha-Methyltyrosine; Animals; Clonidine; Corticosterone; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methyltyrosines; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Norepinephrine stimulation of phosphoinositide hydrolysis in rat cerebral cortex is associated with the alpha1-adrenoceptor.
Topics: Animals; Cerebral Cortex; Clonidine; Hydrolysis; Isoproterenol; Male; Norepinephrine; Phenylephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Inhibitory presynaptic effect of noradrenaline on the hypogastric ganglion of the guinea pig.
Topics: Acetylcholine; Animals; Clonidine; Electric Stimulation; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Neurosecretory Systems; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Synaptic Transmission; Vas Deferens; Yohimbine | 1984 |
Modulation of alpha 2-adrenergic receptors of rat vas deferens by adenosine receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding Sites; Clonidine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Purinergic; Vas Deferens; Yohimbine | 1984 |
Age and day-night changes in clonidine-induced analgesia in mice.
Topics: Age Factors; Analgesia; Animals; Circadian Rhythm; Clonidine; Male; Mice; Mice, Inbred Strains; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1984 |
Altered platelet alpha 2 adrenoreceptors in orthostatic hypotension.
Topics: Adult; Blood Platelets; Clonidine; Humans; Hypotension, Orthostatic; Kinetics; Male; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Nifedipine and alpha adrenoceptors in rat aorta. II. Role of extracellular calcium in enhanced alpha-2 adrenoceptor-mediated contraction in diabetes.
Topics: Animals; Aorta; Calcium; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Platelet alpha 2-adrenergic receptor binding and plasma catecholamines. Before and during imipramine treatment in patients with panic anxiety.
Topics: Adolescent; Adult; Anxiety Disorders; Blood Platelets; Catecholamines; Clonidine; Dopamine; Epinephrine; Fear; Female; Humans; Imipramine; Male; Norepinephrine; Panic; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
alpha 2 and alpha 1-Adrenoceptors mediate opposing actions on parasympathetic neurons.
Topics: Animals; Cats; Clonidine; Drug Interactions; Ganglia, Parasympathetic; In Vitro Techniques; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1984 |
Amphetamine-clonidine interaction on neurotransmission in the vas deferens of the rat.
Topics: Amphetamine; Animals; Clonidine; Cyclic AMP; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptic Transmission; Vas Deferens; Yohimbine | 1984 |
Quantitative analysis of rat brain alpha 2-receptors discriminated by [3H]clonidine and [3H]rauwolscine.
Topics: Animals; Cerebral Cortex; Clonidine; Edetic Acid; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Manganese; Membranes; Models, Biological; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
Topics: Animals; Azepines; Binding, Competitive; Blood Pressure; Clonidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Myocardium; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Comparison of alpha 2 adrenoreceptors on arterial smooth muscle and brain homogenates from spontaneously hypertensive and Wistar-Kyoto normotensive rats.
Topics: Animals; Arteries; Brain; Clonidine; Epinephrine; Guanabenz; In Vitro Techniques; Male; Membranes; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs.
Topics: Animals; Calcium; Clonidine; Dogs; Dose-Response Relationship, Drug; Guanabenz; Kidney; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Antagonist/agonist-preferring alpha-adrenoceptors or alpha 1/alpha 2-adrenoceptors?
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; In Vitro Techniques; Male; Piperoxan; Pulmonary Artery; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
A method for the differentiation of presynaptic inhibitors of adrenergic neurotransmitter release.
Topics: Animals; Blood Pressure; Bretylium Compounds; Clonidine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Neurotransmitter Agents; Rats; Sympathetic Nervous System; Synapses; Yohimbine | 1980 |
Pre- and postsynaptic alpha-adrenoceptor antagonists: differentiated cardiovascular effects in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Pentobarbital; Phenoxybenzamine; Phentolamine; Prazosin; Premedication; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Involvement of central alpha 2-adrenoceptors in the mediation of clonidine-induced hypotension in the cat.
Topics: Animals; Blood Pressure; Cats; Clonidine; Female; Hypotension; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Characterization of alpha-adrenoceptors participating in the central hypotensive and sedative effects of clonidine using yohimbine, rauwolscine and corynanthine.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; Drug Interactions; Female; Hypnotics and Sedatives; Male; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1981 |
Involvement of both dopaminergic and alpha-adrenergic receptors in the hypomotility induced by dibenzoyl-6,7-ADTN.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Clonidine; Depression, Chemical; Male; Motor Activity; Naphthalenes; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1981 |
Guanine nucleotides regulate specifically agonist-binding affinity of the alpha 2-adrenergic receptor in white adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Animals; Clonidine; Cricetinae; Dihydroergotoxine; Epinephrine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Alterations in prejunctional adrenoceptor function in guinea pig and rat vas deferens after chronic ganglionic blockade.
Topics: Animals; Chlorisondamine; Clonidine; Electric Stimulation; Ganglionic Blockers; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Nicotinic; Synaptic Transmission; Vas Deferens; Yohimbine | 1981 |
Pre- and postsynaptic alpha-adrenoceptor blocking activity of raubasine in the rat vas deferens.
Topics: Adrenergic beta-Antagonists; Animals; Clonidine; Cocaine; Dose-Response Relationship, Drug; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Secologanin Tryptamine Alkaloids; Synapses; Vas Deferens; Yohimbine | 1981 |
Inhibitory alpha-2 adrenoceptors in human adipose tissue.
Topics: 1-Naphthylamine; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding Sites; Clonidine; Humans; Imidazoles; In Vitro Techniques; Lipolysis; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Yohimbine | 1981 |
Spinal modulation of acoustic startle: opposite effects of clonidine and d-amphetamine.
Topics: Acoustic Stimulation; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyproheptadine; Dextroamphetamine; Dioxanes; Injections, Spinal; Male; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Reflex, Startle; Spinal Cord; Yohimbine | 1981 |
Cardiovascular effects of clonidine in an avian species, Larus argentatus.
Topics: Adrenergic alpha-Antagonists; Animals; Birds; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Spinal Cord; Vagotomy; Yohimbine | 1981 |
Clonidine-induced potentiation of reflex vagal bradycardia in anaesthetized cats.
Topics: Animals; Cats; Cisterna Magna; Clonidine; Drug Interactions; Female; Heart Rate; Injections; Male; Prazosin; Receptors, Adrenergic, alpha; Reflex; Vagus Nerve; Yohimbine | 1982 |
Differential effects of selective alpha 1- and alpha 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Female; Intraocular Pressure; Male; Phenylephrine; Procaine; Pupil; Yohimbine | 1982 |
A comparison of the cardiovascular and sedative actions of the alpha-adrenoceptor agonists, FLA-136 and clonidine, in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemodynamics; Hydroxydopamines; Hypnotics and Sedatives; Injections, Intraventricular; Male; Methohexital; Naloxone; Oxidopamine; Rats; Rats, Inbred Strains; Triazoles; Yohimbine | 1982 |
Prevention of reserpine rigidity by alpha-2 adrenergic antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Extrapyramidal Tracts; Male; Motor Activity; Muscle Rigidity; Rats; Rats, Inbred Strains; Reserpine; Yohimbine | 1982 |
Pharmacological evidence favoring a similarity between alpha adrenoceptors mediating sleep in chicks and cardiac presynaptic alpha-2 receptors in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chickens; Clonidine; Guanfacine; Guanidines; Heart; Heart Rate; Male; Methoxamine; Nordefrin; Oxymetazoline; Phentolamine; Phenylacetates; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Sleep; Xylazine; Yohimbine | 1982 |
Pharmacological characterization of the alpha adrenoceptors of the dog basilar artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Basilar Artery; Clonidine; Dogs; Female; Male; Mesenteric Arteries; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Renal Artery; Yohimbine | 1982 |
Effects on the 5-hydroxytryptamine-induced head-twitch of drugs with selective actions on alpha1 and alpha2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Methoxamine; Motor Activity; Muridae; Neural Inhibition; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Serotonin; Yohimbine | 1982 |
The role of alpha 2-adrenoceptors in the hypothermic effect of clonidine in the rat.
Topics: Animals; Body Temperature; Clonidine; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors; Tolazoline; Yohimbine | 1982 |
The alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood-Brain Barrier; Cats; Clonidine; Female; Hemodynamics; Hypertension, Renal; Injections, Intraventricular; Male; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine].
Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Decerebrate State; Guanfacine; Guanidines; Heart Rate; Male; Phentolamine; Phenylacetates; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
alpha-Adrenoceptor blocking properties of raubasine in pithed rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Electric Stimulation; Heart Rate; Male; Phenylephrine; Rats; Rats, Inbred Strains; Secologanin Tryptamine Alkaloids; Spinal Cord; Yohimbine | 1982 |
Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: evidence for antidopaminergic properties of some alpha antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Dopamine; Female; Haloperidol; Homovanillic Acid; Male; Prazosin; Rats; Spiperone; Synaptic Transmission; Yohimbine | 1982 |
Interaction of prostaglandins and clonidine in the rat vas deferens.
Topics: Animals; Clonidine; Female; In Vitro Techniques; Male; Muscle, Smooth; Prostaglandins; Rats; Rats, Inbred Strains; Seminal Vesicles; Sheep; Synapses; Vas Deferens; Yohimbine | 1982 |
Noradrenergic-mediated potentiation of acetylcholine release from the phrenic nerve: evidence for presynaptic alpha 1-adrenoceptor involvement.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phentolamine; Phenylephrine; Phrenic Nerve; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Demonstration of alpha-2-adrenoceptor antagonist (yohimbine-like) activity of cirazoline using a hamster fat cell preparation.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Glycerol; Imidazoles; In Vitro Techniques; Lipolysis; Male; Prazosin; Yohimbine | 1982 |
Central alpha-adrenoceptors in cardiovascular regulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Clonidine; Humans; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Relation of central alpha-adrenoceptor and other receptors to the control of renin secretion.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brain Stem; Clonidine; Dogs; Epinephrine; Hydroxydopamines; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Renin; Synapses; Yohimbine | 1983 |
Reversal of the central hypotensive effect of clonidine by intracisternal curare-like agents.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cisterna Magna; Clonidine; Decamethonium Compounds; Dogs; Female; Gallamine Triethiodide; Hypertension; Male; Neuromuscular Nondepolarizing Agents; Pancuronium; Prazosin; Pressoreceptors; Receptors, Adrenergic, alpha; Stimulation, Chemical; Tubocurarine; Yohimbine | 1983 |
Functional postsynaptic alpha 2- but not alpha 1-adrenoceptors in dog saphenous vein exposed to phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Female; In Vitro Techniques; Male; Phenoxybenzamine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Saphenous Vein; Yohimbine | 1982 |
In vitro studies with (imidazolinyl-2)-2-benzodioxane-1-4 ((+/-)-170 150), a new potent alpha 2-adrenoceptor blocking agent.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Clonidine; Dioxins; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Hot Temperature; Hydroxydopamines; Injections, Spinal; Male; Methoxamine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1983 |
CGS 7525A, a new, centrally active alpha 2 adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Clonidine; Male; Mesencephalon; Mianserin; Norepinephrine; Prazosin; Quinones; Rats; Rats, Inbred Strains; Spiperone; Yohimbine | 1983 |
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxins; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tyramine; Vas Deferens; Vasoconstriction; Yohimbine | 1983 |
Use of a sympathetic-cholinergic system in the analysis of sympatho-inhibition produced by clonidine and some congeneric derivatives of clonidine.
Topics: Animals; Cats; Clonidine; Female; Ganglionic Blockers; Male; Parasympathetic Nervous System; Sympathetic Nervous System; Sympatholytics; Yohimbine | 1983 |
Role of alpha-2 adrenergic receptors in the control of diarrhea and intestinal motility.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Antidiarrheals; Clonidine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guinea Pigs; Ileum; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Yohimbine | 1983 |
Role of the autonomic nervous system in the release of rat submandibular gland kallikrein into the circulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Autonomic Nervous System; Carotid Artery Diseases; Clonidine; Electric Stimulation; Kallikreins; Male; Prazosin; Rats; Rats, Inbred Strains; Submandibular Gland; Yohimbine | 1983 |
Alpha 2-adrenoceptors and the delay of castor oil-induced diarrhoea by clonidine in rats.
Topics: Animals; Castor Oil; Clonidine; Diarrhea; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
The cardiovascular effects of MPV 295 [4(5)-2-(2,6-dimethylphenyl)ethylimidazole], a new antihypertensive agent with alpha 2-adrenoceptor agonistic properties.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Cats; Clonidine; Heart Rate; Imidazoles; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Alpha-1 adrenoceptors and calcium in isolated canine coronary arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Clonidine; Coronary Vessels; Dogs; Female; Imidazoles; Male; Methoxamine; Muscle Contraction; Norepinephrine; Phenylephrine; Prazosin; Secologanin Tryptamine Alkaloids; Yohimbine | 1983 |
Effects of clonidine on operant behavior and electric shock titration in the squirrel monkey: effects of alpha 2-adrenoreceptor antagonism.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Male; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Saimiri; Tolazoline; Yohimbine | 1983 |
Modulation by alpha 2-adrenergic stimulation of IgE-mediated 14C-serotonin release from rat mast cells.
Topics: Adrenergic alpha-Agonists; Alprostadil; Animals; Clonidine; Female; Immunoglobulin E; Isoproterenol; Male; Mast Cells; Methoxamine; Mice; Mice, Inbred BALB C; Prostaglandins E; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1983 |
Interaction between noradrenergic and serotonergic brain systems as evidenced by behavioral and biochemical effects of microinjections of adrenergic agonists and antagonists into the median raphe nucleus.
Topics: Adrenergic Agonists; Albuterol; Animals; Brain Stem; Clonidine; Male; Microinjections; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1983 |
Clonidine and para-aminoclonidine, partial agonists for the alpha2-adrenergic receptor on intact human blood platelets.
Topics: Adrenergic alpha-Agonists; Binding, Competitive; Blood Platelets; Clonidine; Cyclic AMP; Humans; Platelet Aggregation; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Inhibition by alpha 2-adrenoceptor agonists of the secretion of catecholamines from isolated adrenal medullary cells.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Animals; Calcium; Catecholamines; Cattle; Clonidine; Diltiazem; In Vitro Techniques; Tubocurarine; Yohimbine | 1983 |
Pre-junctional alpha 2-adrenoceptor activity of B-HT920.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Dioxanes; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Involvement of histaminergic mechanisms in the cataleptogenic effect of clonidine in mice.
Topics: Animals; Apomorphine; Catalepsy; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histidine; Humans; Mice; Phenoxybenzamine; Stereotyped Behavior; Yohimbine | 1983 |
The release of 5-hydroxytryptamine in the occipital and frontal cortex is modulated by different subtypes of alpha-adrenoceptor.
Topics: Animals; Cerebral Cortex; Clonidine; Male; Methoxamine; Potassium; Rats; Receptors, Adrenergic, alpha; Serotonin; Tetrodotoxin; Yohimbine | 1983 |
Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Male; Muscle Contraction; Piperazines; Pupil; Pyridines; Rats; Vas Deferens; Yohimbine | 1983 |
Alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons.
Topics: Adaptation, Physiological; Animals; Cerebellum; Clonidine; Darkness; Dopamine; Male; Neurons; Photic Stimulation; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Retina; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Effects of alpha-adrenoceptor antagonists on clonidine-induced inhibition of insulin secretion by isolated pancreatic islets.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Yohimbine | 1983 |
Characterization of postsynaptic alpha-adrenoceptors in rat aortic strips and portal veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Female; Male; Muscle, Smooth, Vascular; Nordefrin; Oxymetazoline; Phenethylamines; Portal Vein; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Yohimbine | 1983 |
Interactions of neuroleptic compounds at alpha 2-adrenergic receptor affinity states in bovine caudate nucleus.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Cattle; Caudate Nucleus; Clonidine; In Vitro Techniques; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Biochemical pharmacology of paradoxical sleep.
Topics: alpha-Methyltyrosine; Animals; Chlorpromazine; Clonidine; Humans; Hydroxydopamines; Locus Coeruleus; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Methyltyrosines; Norepinephrine; Oxidopamine; Piperoxan; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Serotonin; Sleep, REM; Synaptic Transmission; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Selective stimulation of vascular postjunctional alpha-adrenoreceptors by (-)-amidephrine in rats and cats.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Ethanolamines; Female; Heart Rate; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Species Specificity; Spinal Cord; Yohimbine | 1983 |
Comparison of alpha-2 adrenergic receptors and their regulation in rodent and porcine species.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Guanosine Triphosphate; Lung; Magnesium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Submandibular Gland; Swine; Tritium; Yohimbine | 1984 |
Presynaptic alpha 2 -adrenergic stimulation leads to growth hormone release in the dog.
Topics: Adrenergic alpha-Agonists; Animals; Clemastine; Clonidine; Dogs; Drug Interactions; Female; Growth Hormone; Male; Metergoline; Mianserin; Synapses; Triazoles; Yohimbine | 1984 |
A regional difference in the distribution of postsynaptic alpha-adrenoceptor subtypes in canine veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Epinephrine; Female; Guanethidine; Heart Rate; Male; Nordefrin; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spinal Nerves; Yohimbine | 1983 |
A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxins; Dose-Response Relationship, Drug; Heart Rate; Hypnotics and Sedatives; Idazoxan; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1984 |
alpha- 1 and alpha-2 type adrenoceptors involved in the inhibitory effect of splanchnic nerves on parasympathetically stimulated gastric acid secretion in rats.
Topics: Animals; Bethanechol; Bethanechol Compounds; Clonidine; Electric Stimulation; Gastric Acid; Male; Parasympathetic Nervous System; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Splanchnic Nerves; Vagus Nerve; Yohimbine | 1984 |
A physiological and pharmacological analysis of the electrodermal response in the rat.
Topics: Animals; Antihypertensive Agents; Atropine; Brain; Clonidine; Electric Stimulation; Evoked Potentials; Female; Galvanic Skin Response; Hexamethonium; Hexamethonium Compounds; Male; Rats; Stereotaxic Techniques; Sympathetic Nervous System; Yohimbine | 1984 |
Pharmacological characterization of postjunctional alpha-adrenoceptors in isolated human omental arteries and veins.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Clonidine; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Omentum; Oxymetazoline; Phenylephrine; Prazosin; Veins; Yohimbine | 1984 |
Effect of clonidine at steady state on blood pressure in spontaneously hypertensive rats. Interaction of various alpha-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Benzimidazoles; Blood Pressure; Clonidine; Dioxanes; Drug Interactions; Hypertension; Male; Phentolamine; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1984 |
Analysis of the hypotensive effects of medroxalol and its enantiomers, MDL 17,330A and MDL 17,331A.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dogs; Ethanolamines; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Yohimbine | 1984 |
Alpha-adrenoceptor- and prostaglandin-mediated modulation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Animals; Autonomic Fibers, Postganglionic; Azepines; Blood Pressure; Clonidine; Dinoprostone; Electric Stimulation; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Neurotransmitter Agents; Norepinephrine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1984 |
Assessment of alpha-adrenergic receptor subtypes in isolated rat aortic segments.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Yohimbine and rauwolscine reduce food intake of genetically obese (obob) and lean mice.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Clonidine; Dose-Response Relationship, Drug; Drinking; Eating; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Norepinephrine; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Facilitation at single release sites of a sympathetic neuroeffector junction in the mouse.
Topics: Action Potentials; Animals; Clonidine; Male; Mice; Mice, Inbred C57BL; Neuroeffector Junction; Neurotransmitter Agents; Sympathetic Nervous System; Vas Deferens; Yohimbine | 1984 |
Duration of tonic immobility in chickens as a function of alpha-adrenergic receptor stimulation and blockade.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Chickens; Clonidine; Guanfacine; Guanidines; Methoxamine; Naphazoline; Phenylacetates; Phenylephrine; Prazosin; Restraint, Physical; Time Factors; Yohimbine | 1984 |
Effects of clonidine and some alpha-adrenergic antagonists alone and in combination on schedule-controlled behavior in pigeons and mice.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Columbidae; Conditioning, Operant; Drug Interactions; Male; Mice; Prazosin; Reinforcement Schedule; Species Specificity; Yohimbine | 1984 |
Alpha-adrenoceptor antagonism by apoyohimbine and some observations on the pharmacology of alpha-adrenoceptors in the rat anococcygeus and vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Electric Stimulation; Ethanolamines; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Vas Deferens; Xylazine; Yohimbine | 1984 |
Effect of alpha 2 adrenergic agents upon central etorphine antinociception in the cat.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Clonidine; Drug Interactions; Etorphine; Guanfacine; Guanidines; Kinetics; Male; Morphinans; Nociceptors; Pain; Phenylacetates; Yohimbine | 1984 |
Episodic growth hormone secretion in the domestic fowl (Gallus domesticus): alpha adrenergic regulation.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chickens; Clonidine; Ditiocarb; Growth Hormone; Male; Methyltyrosines; Phenoxybenzamine; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Alpha 1- and alpha 2-adrenoceptors in the smooth muscle of isolated rabbit urinary bladder and urethra.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Urethra; Urinary Bladder; Yohimbine | 1984 |
Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Binding, Competitive; Cerebral Cortex; Clonidine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Effect of alpha adrenergic agonists and blockers on Purkinje fiber transmembrane potentials and automaticity in the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart Conduction System; In Vitro Techniques; Membrane Potentials; Phenylephrine; Prazosin; Purkinje Fibers; Yohimbine | 1984 |
Reduced alpha 2-adrenoceptor binding in lower brainstem of stroke-prone spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brain Stem; Cerebrovascular Disorders; Clonidine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Effect of removing the endothelial cells on the reactivity of rat aortic segments to different alpha-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Clonidine; Endothelium; Imidazoles; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Xylazine; Yohimbine | 1984 |
Noradrenergic modulation of serotonin synthesis and metabolism. I. Inhibition by clonidine in vivo.
Topics: Amphetamine; Animals; Clonidine; Gas Chromatography-Mass Spectrometry; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Yohimbine | 1982 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine | 1984 |
Clonidine inhibits salivary secretion by activation of postsynaptic alpha 2-receptors.
Topics: Animals; Clonidine; Female; Methacholine Compounds; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Salivation; Submandibular Gland; Substance P; Yohimbine | 1984 |
Axonal transport and presynaptic location of alpha 2-adrenoreceptors in locus coeruleus neurons.
Topics: Animals; Axonal Transport; Clonidine; Dioxanes; Hydroxydopamines; Locus Coeruleus; Neural Pathways; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Pharmacological characterization of central alpha-adrenoceptors which mediate clonidine-induced locomotor hypoactivity in the developing rat.
Topics: Aging; Animals; Central Nervous System; Clonidine; Female; Male; Motor Activity; Phentolamine; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1980 |
Postsynaptic alpha 1- and alpha 2-adrenoceptors in the circulatory system of the pithed rat: selective stimulation of the alpha 2-type by B-HT 933.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Oxazoles; Phentolamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Vasomotor System; Yohimbine | 1980 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Antagonism; Female; Methyldopa; Motor Activity; Nordefrin; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Investigation into different types of post- and presynaptic alpha-adrenoceptors at cardiovascular sites in rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Clonidine; Electric Stimulation; Heart Rate; Male; Methoxamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1980 |
Effects of desipramine and yohimbine on alpha 2- and beta-adrenoreceptor sensitivity.
Topics: Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Male; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Yohimbine | 1980 |
Aspects of the pharmacology of prazosin.
Topics: Animals; Cats; Clonidine; Femoral Artery; Femoral Vein; In Vitro Techniques; Mesenteric Arteries; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Rabbits; Receptors, Adrenergic, alpha; Vasodilation; Yohimbine | 1980 |
Evaluation of presynaptic alpha-receptor function in the canine renal vascular bed.
Topics: Animals; Cattle; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Antagonism; Epinephrine; Female; Kidney; Male; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasomotor System; Yohimbine | 1980 |
Evidence that catecholamines stimulate renal gluconeogenesis through an alpha 1-type of adrenoceptor.
Topics: Animals; Clonidine; Gluconeogenesis; Imidazoles; In Vitro Techniques; Kidney Cortex; Male; Methoxamine; Moxisylyte; Norepinephrine; Oxymetazoline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
The role of alpha receptors in the facilitation of the chemoreflex and inhibition of the carotid occlusion reflex by clonidine.
Topics: Animals; Blood Pressure; Carotid Arteries; Carotid Body; Clonidine; Dogs; Female; Male; Phentolamine; Piperoxan; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1980 |
Identification of alpha 2-adrenergic receptors in human fat cell membranes by [3H]chlonidine binding.
Topics: 1-Naphthylamine; Adipose Tissue; Binding, Competitive; Cell Membrane; Clonidine; Humans; Imidazoles; In Vitro Techniques; Kinetics; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
The role of sodium pump activity in the hyperpolarization and in subsequent depolarization of smooth muscle in response to stimulation of post-synaptic alpha 1-adrenoceptors.
Topics: Animals; Calcium; Clonidine; Colon; Epinephrine; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ouabain; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1980 |
Alpha-adrenergic stimulation by clonidine increases plasma concentrations of immunoreactive beta-endorphin in rats.
Topics: Animals; beta-Endorphin; Clonidine; Endorphins; Hypophysectomy; Kinetics; Male; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Lack of modulation by presynaptic alpha 2-adrenoceptors of adrenergic transmitters release evoked by activation of 5-hydroxytryptamine and nicotine receptors.
Topics: Animals; Clonidine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Heart; Heart Rate; In Vitro Techniques; Male; Norepinephrine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Nicotinic; Receptors, Serotonin; Serotonin; Yohimbine | 1981 |
Importance of norepinephrine alpha 2-receptor activation for morphine-induced rat growth hormone secretion.
Topics: Animals; Clonidine; Fenclonine; Growth Hormone; Haloperidol; Kinetics; Male; Morphine; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Yohimbine | 1981 |
Clonidine releases immunoreactive beta-endorphin from rat para distalis.
Topics: Animals; beta-Endorphin; Cells, Cultured; Clonidine; Endorphins; Male; Organ Specificity; Phenoxybenzamine; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Propranolol; Rats; Yohimbine | 1981 |
Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog.
Topics: Animals; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Heart Rate; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stereoisomerism; Subclavian Artery; Synapses; Yohimbine | 1981 |
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Involvement of alpha 1-adrenergic receptors in the inhibitory effect of catecholamines on the thyrotropin-induced release of thyroxine by the mouse thyroid.
Topics: Animals; Clonidine; Cyclic AMP; Kinetics; Male; Methoxamine; Mice; Mice, Inbred Strains; Norepinephrine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thyroid Gland; Thyrotropin; Thyroxine; Yohimbine | 1982 |
Functional characterization of postjunctional alpha-adrenoceptors in rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1981 |
Alpha-noradrenaline modulation of D,L-allylgycine seizures.
Topics: Allylglycine; Animals; Clonidine; Glycine; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Seizures; Yohimbine | 1981 |
Differential effects of pharmacological manipulations of central alpha 1- and alpha 2-adrenergic receptors on the secretion of thyrotropin and growth hormone in male rats.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Growth Hormone; Hypothalamus; Kinetics; Male; Methoxamine; Methoxyhydroxyphenylglycol; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Thyrotropin; Yohimbine | 1982 |
Clonidine inhibition of pancreatic secretion in rats: a possible central site of action.
Topics: Animals; Clonidine; Deoxyglucose; Gastric Juice; Male; Mianserin; Pancreas; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
In vivo alpha 2-adrenoceptor-mediated inhibition of isoproterenol-stimulated free fatty acid output in dog bone marrow adipose tissue.
Topics: Adipose Tissue; Animals; Bone Marrow; Clonidine; Dogs; Fatty Acids, Nonesterified; Isoproterenol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Antinociceptive actions of clonidine.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Morphine; Muridae; Naloxone; Nociceptors; Phenoxybenzamine; Premedication; Receptors, Adrenergic; Receptors, Opioid; Spinal Cord; Yohimbine | 1981 |
Interaction of verapamil with human platelet alpha-adrenergic receptors.
Topics: Binding, Competitive; Blood Platelets; Clonidine; Dihydroergotoxine; Epinephrine; Humans; Kinetics; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1982 |
Discrepancy in the regulatory effects of sodium and guanine nucleotides on adrenaline and clonidine binding to alpha 2-adrenoceptors in human fat cell membranes.
Topics: Adipose Tissue; Binding Sites; Cell Membrane; Clonidine; Epinephrine; Guanine Nucleotides; Humans; In Vitro Techniques; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1981 |
Anticonvulsant effects of clonidine mediated through central alpha2-adrenoceptors.
Topics: Animals; Anticonvulsants; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Effect of yohimbine and its diastereoisomers on clonidine-induced depression of exploration in the rat.
Topics: Animals; Clonidine; Drug Interactions; Exploratory Behavior; Male; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Yohimbine | 1982 |
alpha 2-Adrenergic receptor regulation of ion transport in rabbit ileum.
Topics: Animals; Biological Transport, Active; Clonidine; Epinephrine; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Methoxamine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Clonidine p-isothiocyanate, an affinity label for alpha 2-adrenergic receptors on human platelets.
Topics: Adenylyl Cyclase Inhibitors; Affinity Labels; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Epinephrine; Humans; Ligands; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Heterogeneity of postsynaptic Alpha adrenergic receptors in mammalian aortas.
Topics: Animals; Aorta, Thoracic; Cats; Clonidine; Cricetinae; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Mesocricetus; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1982 |
Studies on desensitization of adrenergic receptors of human adipocytes.
Topics: Adipose Tissue; Clonidine; Cyclic AMP; Dihydroalprenolol; Epinephrine; Humans; Isoproterenol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1982 |
Magnesium reduces affinities of antagonists at rat cortex alpha 2-adrenergic receptors labeled with 3H-clonidine: evidence for heterogeneity of alpha 2-receptor conformations with respect to antagonists.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clonidine; Guanosine Triphosphate; Magnesium; Magnesium Chloride; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Alpha-2 adrenergic antilipolytic effect in dog fat cells: incidence of obesity and adipose tissue localization.
Topics: Adipose Tissue; Animals; Clonidine; Dogs; Epinephrine; Isoproterenol; Lipolysis; Obesity; Prazosin; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Yohimbine | 1982 |
Mechanism of the clonidine-induced protection against acetylcholinesterase inhibitor toxicity.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Clonidine; Drug Interactions; Male; Mice; Mice, Inbred ICR; Motor Neurons; Neostigmine; Physostigmine; Premedication; Receptors, Adrenergic, alpha; Respiratory Paralysis; Yohimbine | 1982 |
Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Anxiety; Blood Pressure; Clonidine; Depression; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Effects of chronic treatment with imipramine on the behavioural and electroencephalographic modifications induced by clonidine in the rat.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Cortical Synchronization; Electroencephalography; Imipramine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Functional subsensitivity of alpha 2-adrenoceptors accompanies reductions in yohimbine binding after clorgyline treatment.
Topics: Animals; Clonidine; Clorgyline; In Vitro Techniques; Male; Motor Activity; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Noradrenergic neurotransmission in the brain of a convulsive mutant mouse, differences between the cerebral cortex and the brain stem.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Clonidine; Female; Male; Mice; Mice, Inbred C57BL; Mice, Quaking; Norepinephrine; Seizures; Synaptic Transmission; Yohimbine | 1982 |
Kinetic studies on MSH and alpha 2-adrenoceptor interaction on the Anolis melanophore.
Topics: Animals; Cells, Cultured; Clonidine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Kinetics; Lizards; Melanocyte-Stimulating Hormones; Melanophores; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Skin Pigmentation; Yohimbine | 1982 |
Demonstration of alpha 2-adrenergic receptors in rat pancreatic islets using radioligand binding (41498).
Topics: Animals; Clonidine; Epinephrine; Islets of Langerhans; Isoproterenol; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Enterocyte alpha 2-adrenergic receptors: yohimbine and p-aminoclonidine binding relative to ion transport.
Topics: Animals; Binding, Competitive; Biological Transport; Cell Membrane; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Electrophysiology; Guanosine Triphosphate; Ileum; Male; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1983 |
Evidence supporting the existence of presynaptic alpha-adrenoceptors in the regulation of endogenous noradrenaline release upon hepatic sympathetic nerve stimulation in the dog liver in vivo.
Topics: Animals; Catecholamines; Clonidine; Dogs; Electric Stimulation; Liver; Liver Circulation; Male; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1982 |
Locomotor activity of rats after stimulation of the nucleus locus coeruleus region or after lesion of the dorsal noradrenergic bundle: effects of clonidine, prazosin and yohimbine.
Topics: Animals; Brain Stem; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Exploratory Behavior; Hippocampus; Hydroxydopamines; Locus Coeruleus; Male; Motor Activity; Neural Pathways; Norepinephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1982 |
Effects of 4-chloro-2-(2-imidazolin-2-ylamino)-isoindoline Hydrochloride (BE 6143) at pre- and postsynaptic alpha-adrenoceptors in rabbit aorta and pulmonary artery.
Topics: Animals; Aorta, Thoracic; Clonidine; Electric Stimulation; Female; Imidazoles; In Vitro Techniques; Isoindoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Pulmonary Artery; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
An electrophysiological study of presynaptic alpha-adrenoceptors in the vas deferens of the mouse.
Topics: Animals; Clonidine; Electrophysiology; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neuroeffector Junction; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Yohimbine | 1983 |
Lack of involvement of alpha 2-adrenoceptors in the regulation of striatal dopaminergic transmission.
Topics: Acetylcholine; Animals; Clonidine; Corpus Striatum; Dioxins; Dopamine; Idazoxan; Male; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Yohimbine | 1983 |
The alpha 2-adrenergic receptor of human fat cells: comparative study of alpha 2-adrenergic radioligand binding and biological response.
Topics: Adipose Tissue; Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Female; Humans; Isoproterenol; Lipolysis; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Tritium; Yohimbine | 1982 |
Effects of alpha 1 and alpha 2 activation of adrenergic receptors on aqueous humor dynamics.
Topics: Animals; Aqueous Humor; Cats; Clonidine; Intraocular Pressure; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Characteristics of the [3H]-yohimbine binding on rat brain alpha2-adrenoceptors.
Topics: Animals; Binding Sites; Brain; Calcium; Clonidine; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1982 |
Endogenous and exogenous regulation of human alpha- and beta-adrenergic receptors.
Topics: Adolescent; Adult; Aged; Aging; Blood Platelets; Clonidine; Estrogens; Female; Guanosine Triphosphate; Humans; Iodocyanopindolol; Lymphocytes; Male; Middle Aged; Phentolamine; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1983 |
alpha2-Adrenergic stimulation enhances growth hormone secretion in the dog: a presynaptic mechanism?
Topics: Animals; Clonidine; Dogs; Female; Growth Hormone; Kinetics; Male; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Synapses; Yohimbine | 1983 |
Platelet alpha 2 adrenoreceptors in chronic congestive heart failure.
Topics: Adult; Aged; Blood Platelets; Clonidine; Dopamine; Epinephrine; Female; Heart Failure; Humans; In Vitro Techniques; Male; Middle Aged; Myocardium; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Antagonist properties of phentolamine at both presynaptic alpha 2-adrenoceptors and presynaptic dopamine receptors using field stimulated right cat atria.
Topics: Animals; Apomorphine; Cats; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Yohimbine | 1983 |
Effect of glucocorticoids on alpha-2 adrenoceptors in vas deferens of reserpinized rat in organ culture.
Topics: Animals; Clonidine; Dexamethasone; Glucocorticoids; Hydrocortisone; Kinetics; Male; Organ Culture Techniques; Prazosin; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Yohimbine | 1983 |
Potentiation by yohimbine of pentylenetetrazol-induced seizures in rats: role of alpha 2 adrenergic receptors.
Topics: Animals; Clonidine; Drug Synergism; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Seizures; Yohimbine | 1983 |
The influence of aging on alpha-adrenoceptors in rat heart and vas deferens.
Topics: Aging; Animals; Clonidine; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1983 |
Altered platelet alpha 2-adrenoceptors in patients with angina pectoris.
Topics: Adult; Angina Pectoris; Binding Sites; Blood Platelets; Clonidine; Female; Humans; Male; Middle Aged; Norepinephrine; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tritium; Vasomotor System; Yohimbine | 1983 |
Platelet alpha 2 adrenoreceptors are decreased in number after antidepressant therapy.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Blood Platelets; Brain; Clonidine; Depressive Disorder; Electroconvulsive Therapy; Humans; Kinetics; Lithium; Lithium Carbonate; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Alpha adrenergic receptor subtype associated with receptor binding, Ca++ influx, Ca++ release and contractile events in the rabbit aorta.
Topics: Animals; Aorta; Calcium; Clonidine; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Lipolysis in rat adipose tissue in vitro and its alpha 2 adrenergic control.
Topics: Adipose Tissue; Animals; Clonidine; Dose-Response Relationship, Drug; Epididymis; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
[Comparison of mianserin and yohimbine on presynaptic alpha 2-receptors].
Topics: Animals; Binding, Competitive; Clonidine; Dibenzazepines; Epinephrine; Female; Guinea Pigs; Male; Mianserin; Myenteric Plexus; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1983 |
Pharmacological evidence for high affinity and low affinity a2-adrenoceptor binding sites in rat vas deferens.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Male; Nordefrin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1983 |
Modulation of cortical acetylcholine and gamma-aminobutyric acid release in freely moving guinea pigs: effects of clonidine and other adrenergic drugs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathomimetics; Yohimbine | 1983 |
Studies on the 'turnover' of central alpha-adrenoceptors in the rat using phenoxybenzamine.
Topics: Animals; Brain; Clonidine; Half-Life; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1983 |
Interaction of ergot alkaloids and their combination (co-dergocrine) with alpha-adrenoceptors in the CNS.
Topics: Animals; Brain; Clonidine; Cyclic AMP; Dihydroergotoxine; Dioxanes; Drug Combinations; Ergot Alkaloids; In Vitro Techniques; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Study of two alkylating derivatives: the p-isothiocyanato- and the p-methylisothiocyanato-clonidine.
Topics: Alkylating Agents; Animals; Aorta; Brain; Clonidine; In Vitro Techniques; Male; Membranes; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Antinociceptive activity of N-(4-hydroxyphenacetyl)-4-aminoclonidine, a novel analog of clonidine: role of opioid receptors and alpha-adrenoceptors.
Topics: Analgesics; Animals; Aorta, Thoracic; Benzeneacetamides; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Kinetics; Male; Mice; Morphine; Naloxone; Receptors, Adrenergic, alpha; Receptors, Opioid; Xylazine; Yohimbine | 1983 |
Prejunctional alpha-adrenoceptor mediated prostaglandin releasing effect of clonidine in the isolated perfused rabbit kidney.
Topics: Animals; Aspirin; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Kidney; Lysine; Male; Norepinephrine; Phenylephrine; Prostaglandins; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Chronic opiate treatment does not modify alpha 2-adrenergic receptors in rat cerebral cortex, kidney and in the neurotumor cell line NCB20.
Topics: Animals; Brain; Cell Line; Clonidine; Kidney; Male; Narcotics; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1983 |
[Characteristics of alpha adrenoceptors of lymphatics and their physiological significance].
Topics: Animals; Binding, Competitive; Cattle; Clonidine; In Vitro Techniques; Lymphatic System; Mesentery; Muscle Contraction; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Presynaptic alpha-adrenoceptors: do exogenous and neuronally released noradrenaline act at different sites?
Topics: Animals; Clonidine; Dogs; Dopamine; Feedback; In Vitro Techniques; Nerve Endings; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sulpiride; Synaptic Transmission; Yohimbine | 1984 |
Differential blocking effects of prazosin and yohimbine on vasopressor responses to sympathetic nerve stimulation and intravenous norepinephrine in the pithed rat.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Male; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
Controversial evidence regarding the functional importance of presynaptic alpha receptors.
Topics: Animals; Clonidine; Dogs; Electric Stimulation; Heart; Heart Rate; Kidney; Norepinephrine; Oxymetazoline; Phentolamine; Receptors, Adrenergic, alpha; Synapses; Vasoconstriction; Yohimbine | 1984 |
Islet cyclic AMP levels are not lowered during alpha 2-adrenergic inhibition of insulin release.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antihypertensive Agents; Clonidine; Colforsin; Cyclic AMP; Diterpenes; Epinephrine; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Yohimbine | 1984 |
Functional characterization of the alpha adrenergic receptor modulating the hydroosmotic effect of vasopressin on the rabbit cortical collecting tubule.
Topics: Absorption; Animals; Arginine Vasopressin; Body Water; Cell Membrane Permeability; Clonidine; Female; Kidney Tubules; Kidney Tubules, Collecting; Norepinephrine; Osmosis; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Mechanism of suppression of vasopressin and adrenocorticotropic hormone secretion by clonidine in anesthetized dogs.
Topics: Adrenocorticotropic Hormone; Animals; Clonidine; Dogs; Female; Injections, Intra-Arterial; Injections, Intravenous; Injections, Intraventricular; Male; Oxymetazoline; Vagotomy; Vasopressins; Yohimbine | 1984 |
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Topics: Adult; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Doxazosin; Female; Guanfacine; Guanidines; Heart Rate; Humans; Male; Methoxamine; Muscle, Smooth, Vascular; Phenylacetates; Prazosin; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1984 |
Predominance of alpha 2-adrenoceptors in porcine thyroid: biochemical and pharmacological correlations.
Topics: Animals; Bacterial Toxins; Clonidine; Cyclic AMP; Kinetics; Norepinephrine; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Swine; Thyroid Gland; Thyrotropin; Thyroxine; Virulence Factors, Bordetella; Yohimbine | 1984 |
Alpha-adrenoceptors and facilitation at a sympathetic neuroeffector junction.
Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscle, Smooth; Neural Conduction; Neuroeffector Junction; Piperoxan; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1984 |
The effects of phospholipase and 2-chloroadenosine treatments on alpha 2-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; In Vitro Techniques; Male; Phospholipases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1984 |
Pharmacological characterization of the postsynaptic alpha adrenoceptors in vascular smooth muscle from canine and rat mesenteric vascular beds.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Hydroxydopamines; Muscle, Smooth, Vascular; Naphazoline; Oxidopamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Splanchnic Circulation; Yohimbine | 1984 |
A role for presynaptic alpha 2-adrenoceptors in angiotensin II-induced drinking in rats.
Topics: Angiotensin II; Animals; Clonidine; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Female; Injections, Intraventricular; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Yohimbine | 1984 |
Neurotensin inhibition of canine intestinal motility in vivo via alpha-adrenoceptors.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Gastrointestinal Motility; Male; Myocardial Contraction; Neurotensin; Norepinephrine; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha; Reserpine; Tetrodotoxin; Yohimbine | 1984 |
Evidence against the involvement of a noradrenergic mechanism in the release by diazepam of novelty-induced hypophagia in rats.
Topics: Animals; Anxiety; Clonidine; Diazepam; Drug Interactions; Eating; Guanfacine; Guanidines; Humans; Male; Mice; Norepinephrine; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1984 |
Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats.
Topics: Animals; Clonidine; Hypertension; Male; Naphazoline; Pain; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Clonidine promotes the accumulation of 45Ca in pancreatic beta-cell organelles.
Topics: Animals; Calcium; Calcium Radioisotopes; Clonidine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Mice, Obese; Organoids; Yohimbine | 1983 |
The role of brain norepinephrine in clonidine suppression of isolation-induced distress in the domestic chick.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Chickens; Clonidine; Hydroxydopamines; Norepinephrine; Oxidopamine; Social Isolation; Vocalization, Animal; Yohimbine | 1983 |
Clonidine-induced hypothermia: possible involvement of cholinergic and serotonergic mechanisms.
Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Animals; Atropine; Body Temperature; Clonidine; Cyproheptadine; Hypothalamus; Male; Microinjections; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1984 |
Clonidine inhibits nicotinic effects in ganglia of the cholinergic-sympathetic system.
Topics: Animals; Blood Pressure; Cats; Clonidine; Denervation; Dimethylphenylpiperazinium Iodide; Female; Galvanic Skin Response; Ganglia, Autonomic; Heart Rate; Male; Receptors, Nicotinic; Spinal Cord; Time Factors; Vagotomy; Yohimbine | 1984 |
Drinking: a final common pathway?
Topics: Angiotensin II; Animals; Clonidine; Drinking Behavior; Drug Combinations; Female; Isoproterenol; Male; Naloxone; Rats; Rats, Inbred Strains; Yohimbine | 1984 |
Cross generalization with LSD and yohimbine in the rat.
Topics: Animals; Clonidine; Discrimination, Psychological; Generalization, Response; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Xylazine; Yohimbine | 1984 |
Effects of aminotetralins on intraocular pressure and pupillary function in rabbits.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Intraocular Pressure; Male; Naphthalenes; Pupil; Rabbits; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1984 |
Noradrenaline uptake inhibitors do not reduce the presynaptic action of clonidine on 3H-noradrenaline release in superfused synaptosomes.
Topics: Animals; Clonidine; Cocaine; Desipramine; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1984 |
Evidence for two opposite effects of clonidine on gastric acid secretion in the dog.
Topics: Animals; Bethanechol Compounds; Clonidine; Dogs; Gastric Acid; Histamine; Pentagastrin; Yohimbine | 1984 |
Factors influencing the release of noradrenaline from hypothalamic slices of the possum, Trichosurus vulpecula.
Topics: Animals; Catecholamines; Clonidine; Female; Hypothalamus; In Vitro Techniques; Male; Marsupialia; Norepinephrine; Potassium; Yohimbine | 1984 |
Adrenoceptor-mediated responses in human skin studied by iontophoresis.
Topics: Adult; Clonidine; Erythema; Humans; Iontophoresis; Isoproterenol; Middle Aged; Phentolamine; Phenylephrine; Practolol; Prenalterol; Propranolol; Receptors, Adrenergic; Skin; Terbutaline; Vasoconstriction; Yohimbine | 1984 |
The effect of clonidine and yohimbine on audiogenic seizures (AGS) in rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Clonidine; Norepinephrine; Rats; Seizures; Yohimbine | 1984 |
Effects of yohimbine on endogenous noradrenaline release from hypothalamus and brainstem slices of spontaneously hypertensive rats.
Topics: Animals; Brain Stem; Clonidine; Electric Stimulation; Hypertension; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Yohimbine | 1984 |
3H-clonidine and 3H-rauwolscine binding to membranes from rat cerebral cortex and kidney.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Clonidine; Kidney; Male; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Changes in clonidine effect on longitudinal muscle-myenteric plexus strip preparation by morphine treatments.
Topics: Animals; Clonidine; Guinea Pigs; Morphine; Muscle, Smooth; Myenteric Plexus; Naloxone; Prazosin; Yohimbine | 1983 |
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine | 1983 |
Effects of clonidine on the rate of noradrenaline turnover in discrete areas of the rat central nervous system.
Topics: alpha-Methyltyrosine; Animals; Catecholamines; Central Nervous System; Clonidine; Histocytochemistry; Male; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
[Effect of clonidine and adrafinil on biliary secretion in the rat].
Topics: Animals; Bile; Clonidine; Drug Interactions; Hydroxamic Acids; Male; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Yohimbine exacerbates and clonidine attenuates acute morphine withdrawal in rats.
Topics: Animals; Behavior, Animal; Clonidine; Drug Interactions; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance Withdrawal Syndrome; Yohimbine | 1983 |
Differences between the prejunctional effects of phenylephrine and clonidine in guinea-pig isolated atria.
Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Sympathetic Nervous System; Yohimbine | 1984 |
Determination of normetanephrine, 3,4-dihydroxyphenylethyleneglycol (free and total), and 3-methoxy-4-hydroxyphenylethyleneglycol (free and total) in rat brain by high-performance liquid chromatography with electrochemical detection and effects of drugs o
Topics: Animals; Brain Chemistry; Chlorpromazine; Chromatography, High Pressure Liquid; Clonidine; Glycols; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Yohimbine | 1984 |
Effects of clonidine and xylazine on body temperature in the rat.
Topics: Animals; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Rats; Rats, Inbred Strains; Temperature; Thiazines; Time Factors; Xylazine; Yohimbine | 1984 |
Noradrenergic inhibition of the nicotinically-stimulated release of acetylcholine from guinea-pig ileal synaptosomes.
Topics: Acetylcholine; Animals; Clonidine; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Ileum; In Vitro Techniques; Norepinephrine; Piperazines; Receptors, Nicotinic; Sympathomimetics; Synaptosomes; Yohimbine | 1984 |
Effects of the training dose on generalization of morphine stimulus to clonidine.
Topics: Animals; Clonidine; Conditioning, Operant; Discrimination Learning; Generalization, Stimulus; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Yohimbine | 1984 |
Factors influencing the release of purines and norepinephrine in the rabbit portal vein.
Topics: Adrenergic Fibers; Animals; Clonidine; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Portal Vein; Prazosin; Purines; Rabbits; Yohimbine | 1982 |
An analysis of the effects of systemically administered clonidine on the food and water intake of rats.
Topics: Animals; Clonidine; Drinking; Drug Interactions; Eating; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Time Factors; Yohimbine | 1983 |
Effects of yohimbine and tolazoline on isoproterenol and angiotensin II-induced water intake in rats.
Topics: Angiotensin II; Animals; Clonidine; Drinking; Drug Interactions; Female; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Rats; Rats, Inbred Strains; Tolazoline; Yohimbine | 1983 |
Altered hindlimb extension in the rat after DSP-4: a useful marker of central noradrenergic depletion.
Topics: Amines; Animals; Behavior, Animal; Benzylamines; Brain; Clonidine; Drug Interactions; Hindlimb; Male; Neurotoxins; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Comparison of yohimbine, mianserin, chlorpromazine and prazosin as antagonists of the suppressant effect of clonidine on operant behavior.
Topics: Animals; Behavior, Animal; Chlorpromazine; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Mianserin; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine.
Topics: Adult; Anxiety; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Diazepam; Drug Interactions; Female; Humans; Kinetics; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Yohimbine | 1983 |
Analysis of CNS sympatho-inhibition produced by guanabenz.
Topics: Animals; Blood Pressure; Cats; Central Nervous System; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Ganglia, Sympathetic; Guanabenz; Guanidines; Heart Rate; Hypothalamus; Male; Peripheral Nerves; Sympathetic Nervous System; Yohimbine | 1983 |
Clonidine analgesia and suppression of operant responding: dissociation of mechanism.
Topics: Analgesics; Animals; Clonidine; Conditioning, Operant; Drug Interactions; Fluoxetine; Male; Norepinephrine; Phenoxybenzamine; Rats; Xylazine; Yohimbine | 1981 |
The effects of acute and repeated treatment with salbutamol, a beta-adrenoceptor agonist, on clonidine-induced hypoactivity in rats.
Topics: Albuterol; Animals; Clonidine; Desipramine; Drug Interactions; Exploratory Behavior; Fluoxetine; Imipramine; Male; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
[Studies on the antinociceptive activity of guanabenz, with particular reference to clonidine and morphine (author's transl)].
Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Guanabenz; Guanidines; Guinea Pigs; Ileum; In Vitro Techniques; Locomotion; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
Yohimbine inhibits the potentiation by moderate cooling of norepinephrine-induced contractions of canine blood vessels.
Topics: Animals; Clonidine; Cold Temperature; Dogs; In Vitro Techniques; Norepinephrine; Saphenous Vein; Vasoconstriction; Yohimbine | 1982 |
Pharmacology of B-HT 920 in some isolated smooth muscles of the guinea-pig.
Topics: Animals; Aorta; Azepines; Clonidine; Dogs; Drug Interactions; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Trachea; Vas Deferens; Yohimbine | 1982 |
Morphine-like effects of clonidine on the EEG, slow wave sleep and behavior in the dog.
Topics: Animals; Autonomic Nervous System; Behavior, Animal; Clonidine; Dogs; Electroencephalography; Injections, Intravenous; Injections, Intraventricular; Male; Morphine; Naloxone; Sleep; Yohimbine | 1982 |
Brain 3,4-dihydroxyphenylethyleneglycol levels are dependent on central noradrenergic neuron activity.
Topics: Animals; Brain; Cerebral Cortex; Clonidine; Dioxins; Electric Stimulation; Glycols; Hippocampus; Idazoxan; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine | 1982 |
Copulation-induced abbreviation of estrus in the female guinea pig: block by clonidine.
Topics: Animals; Clonidine; Copulation; Estrus; Female; Guinea Pigs; Methysergide; Pimozide; Pregnancy; Sexual Behavior, Animal; Yohimbine | 1980 |
Tonic descending inhibition of the spinal somato-sympathetic reflex from the lower brain stem.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Brain Stem; Cats; Cerebral Cortex; Clonidine; Denervation; Evoked Potentials; Female; Intercostal Nerves; Male; Nerve Block; Neural Inhibition; Pressoreceptors; Reflex; Spinal Cord; Spinal Nerves; Thoracic Nerves; Yohimbine | 1980 |
Brain noradrenergic neuronal activity affects 3,4-dihydroxyphenylethyleneglycol (DHPG) levels.
Topics: Animals; Brain Chemistry; Clonidine; Glycols; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Yohimbine | 1981 |
Analysis of pupillary dilation produced by analogs of clonidine.
Topics: Animals; Cats; Clonidine; Electric Stimulation; Female; Male; Neurons; Pupil; Yohimbine | 1981 |
Clonidine increases food and protein consumption in rats.
Topics: Animals; Appetite Regulation; Clonidine; Dietary Carbohydrates; Dietary Proteins; Dose-Response Relationship, Drug; Male; Rats; Yohimbine | 1980 |
Cardiovascular effects following clonidine microinjection into the nucleus tractus solitarii of the rat.
Topics: Animals; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; Rats; Yohimbine | 1980 |
alpha- and beta-adrenoreceptor-mediated control of brain noradrenaline neurons and antihypertensive therapy.
Topics: Action Potentials; Albuterol; Animals; Brain; Clonidine; Dopamine; Hypertension; Locus Coeruleus; Male; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic; Yohimbine | 1980 |
Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Calcimycin; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Indoles; Isoindoles; Male; Norepinephrine; Pain Measurement; Peripheral Nervous System; Quinoxalines; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Role of alpha 1 and alpha 2-adrenoceptors of the lateral hypothalamic area on urinary excretion caused by centrally administered angiotensin II.
Topics: Angiotensin II; Animals; Clonidine; Drug Interactions; Hypothalamus; Male; Potassium; Prazosin; Rats; Rats, Inbred Strains; Sodium; Urination; Yohimbine | 1995 |
The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5-HT release in the frontal cortex of freely-moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonidine; Dialysis; Diazepam; Drug Interactions; Extracellular Space; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Yohimbine | 1993 |
Role of L-type calcium channels on yohimbine-precipitated clonidine withdrawal in vivo and in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Calcium Channels; Clonidine; Diltiazem; Dose-Response Relationship, Drug; Drug Implants; Female; Ileum; In Vitro Techniques; Isomerism; Mice; Muscle Contraction; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Verapamil; Yohimbine | 1993 |
The role of calcium and alpha-adrenoceptors in contractile response of chick expansor secundariorum muscle to field stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Chloride; Chickens; Clonidine; Electric Stimulation; Ethanol; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscles; Nifedipine; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1994 |
Alpha-adrenoceptors and angiotensinogen gene expression in opossum kidney cells.
Topics: Adrenergic alpha-Agonists; Affinity Labels; Alkaloids; Angiotensinogen; Animals; Cells, Cultured; Clonidine; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Kidney Tubules; Opossums; Phenylephrine; Prazosin; Protein Kinase C; Receptors, Adrenergic, alpha; Staurosporine; Tetradecanoylphorbol Acetate; Yohimbine | 1995 |
Anxiolytic-like effects of yohimbine in the murine plus-maze: strain independence and evidence against alpha 2-adrenoceptor mediation.
Topics: Animals; Anxiety; Behavior, Animal; Clonidine; Dioxanes; Genotype; Idazoxan; Imidazoles; Mice; Mice, Inbred Strains; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Alpha 2-adrenergic stimulation counteracts glucose-induced rise of sodium in pancreatic islets exposed to ouabain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bucladesine; Calcium Channel Blockers; Clonidine; Diltiazem; Dose-Response Relationship, Drug; Gallopamil; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Mice; Mice, Obese; Sodium; Tolbutamide; Yohimbine | 1995 |
Alpha-adrenergic pathways in the lateral hypothalamus are important for the dipsogenic effect of carbachol injected into the medial septal area.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drinking; Hypothalamic Area, Lateral; Male; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1995 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Cardiovascular effects of agmatine, a "clonidine-displacing substance", in conscious rabbits.
Topics: Action Potentials; Agmatine; Animals; Binding, Competitive; Blood Pressure; Cerebral Cortex; Cisterna Magna; Clonidine; Electric Stimulation; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Injections; Kidney; Male; Rabbits; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Yohimbine | 1995 |
Clonidine suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced reductions of striatal dopamine and tyrosine hydroxylase activity in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenergic alpha-Agonists; Animals; Clonidine; Corpus Striatum; Dopamine Antagonists; Imidazoles; Male; Mice; Mice, Inbred C57BL; Tyrosine 3-Monooxygenase; Yohimbine | 1995 |
Characterization of alpha 1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulation.
Topics: Adrenergic Antagonists; Animals; Clonidine; Electric Stimulation; Humans; Hyperplasia; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Yohimbine | 1995 |
Histaminergic mechanisms in clonidine induced analgesia in rat tail-flick test.
Topics: Analgesics; Animals; Clonidine; Cold Temperature; Histamine; Histidine Decarboxylase; Male; Methylhistidines; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Restraint, Physical; Stress, Psychological; Yohimbine | 1995 |
Alpha 2 adrenoceptor- and imidazoline-preferring binding sites in the dog kidney.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Dioxanes; Dogs; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Male; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1995 |
Influence of clonidine on alloxan-induced diabetes in rats.
Topics: Alloxan; Animals; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Imidazoline Receptors; Insulin; Male; Rats; Rats, Wistar; Receptors, Drug; Yohimbine | 1995 |
Increased pressure in venous sinusoids during decongestion of rat nasal mucosa induced by adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Volume; Clonidine; Extracellular Space; Female; Hemodynamics; Lasers; Nasal Decongestants; Nasal Mucosa; Norepinephrine; Paranasal Sinuses; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance; Veins; Yohimbine | 1993 |
[Alpha adrenergic mechanism on the reflex micturition in the male decerebrate dog].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Decerebrate State; Dogs; Male; Manometry; Midodrine; Prazosin; Reflex; Urethra; Urinary Bladder; Urination; Urodynamics; Yohimbine | 1993 |
Orthostatic hypotension.
Topics: Cerebrovascular Circulation; Clonidine; Deamino Arginine Vasopressin; Dihydroergotamine; Dopamine; Epinephrine; Humans; Hypotension, Orthostatic; Metoclopramide; Octreotide; Patient Education as Topic; Pindolol; Yohimbine | 1994 |
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Characteristics of the alpha 2/beta 2-adrenergic receptor-coupled adenylyl cyclase system in rat myometrium during pregnancy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Base Sequence; Cell Membrane; Clonidine; DNA Primers; Female; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Molecular Sequence Data; Myometrium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Virulence Factors, Bordetella; Yohimbine | 1995 |
Adrenocorticotropin, prolactin and beta-endorphin stimulatory actions of alpha-2-adrenoceptor antagonists.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Clonidine; Dexamethasone; Hypothalamus, Middle; Injections, Intraventricular; Male; Prolactin; Rats; Rats, Wistar; Stimulation, Chemical; Yohimbine | 1995 |
Alpha-2 adrenoceptors modulate the somatostatinergic system and G protein levels in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Clonidine; Colforsin; GTP-Binding Proteins; Hippocampus; Kinetics; Male; Membranes; Pertussis Toxin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Somatostatin; Virulence Factors, Bordetella; Yohimbine | 1995 |
Effects of clonidine and yohimbine on parasympathetic reflex salivation and vasodilatation in cat SMG.
Topics: Animals; Autonomic Agents; Autonomic Nerve Block; Cats; Clonidine; Electric Stimulation; Facial Nerve; Female; Male; Methacholine Chloride; Parasympathetic Nervous System; Reflex; Salivation; Submandibular Gland; Sympathetic Nervous System; Vasodilation; Yohimbine | 1995 |
Spinal nonadrenergic imidazoline receptors do not mediate the antinociceptive action of intrathecal clonidine in the rat.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Binding, Competitive; Clonidine; Dioxanes; Idazoxan; Imidazoline Receptors; Injections, Spinal; Male; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Spinal Cord; Yohimbine | 1995 |
Characterization of binding sites for [3H]-idazoxan, [3H]-P-aminoclonidine and [3H]-rauwolscine in the kidney of the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Clonidine; Dioxanes; Dogs; GTP-Binding Proteins; Idazoxan; Imidazoline Receptors; Kidney; Male; Radioligand Assay; Receptors, Drug; Yohimbine | 1994 |
Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?
Topics: Adrenal Glands; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Clonidine; Cortodoxone; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desoxycorticosterone; Drug Interactions; Drug Therapy, Combination; Gene Expression Regulation; Isoenzymes; Kidney; Liver; Male; Meperidine; Molecular Sequence Data; Morphine; Neurosecretory Systems; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroids; Yohimbine | 1995 |
Medial preoptic alpha-2 adrenoceptors in the regulation of sleep-wakefulness.
Topics: Animals; Clonidine; Electroencephalography; Male; Preoptic Area; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sleep; Wakefulness; Yohimbine | 1995 |
Regulation of endogenous noradrenaline release from the bed nucleus of stria terminalis.
Topics: Animals; Calcium; Clonidine; In Vitro Techniques; Ligands; Male; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, N-Methyl-D-Aspartate; Reserpine; Thalamic Nuclei; Yohimbine | 1995 |
Interactions of chloroethylclonidine with rauwolscine- and prazosin-sensitive adrenoceptors in dog saphenous vein.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Clonidine; Dioxanes; Dogs; Extracellular Space; In Vitro Techniques; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Saphenous Vein; Yohimbine | 1994 |
Desipramine-induced increase in norepinephrine transporter mRNA is not mediated via alpha 2 receptors.
Topics: Animals; Carrier Proteins; Clonidine; Desipramine; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; RNA, Messenger; Symporters; Yohimbine | 1994 |
Alpha 2-adrenoceptor-mediated inhibition of bulbospinal barosensitive cells of rat rostral medulla.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Injections, Intravenous; Iontophoresis; Male; Medulla Oblongata; Neurons; Nordefrin; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 1993 |
Effect of alpha 2-adrenergic drugs on REM sleep deprivation-induced increase in swimming activity.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Adrenergic, alpha-2; Sleep Deprivation; Sleep, REM; Swimming; Yohimbine | 1993 |
Clonidine and phenylephrine injected into the lateral preoptic area reduce water intake in dehydrated rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dehydration; Drinking Behavior; Injections; Male; Phenylephrine; Prazosin; Preoptic Area; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 1993 |
Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Clonidine; Dioxanes; Disease Models, Animal; Hypertension, Renovascular; Idazoxan; Kidney; Male; Natriuresis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Drug; Tritium; Yohimbine | 1993 |
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine | 1993 |
Sympathetic transmission to the dilator muscle of the rat iris.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Iris; Membrane Potentials; Neuroeffector Junction; Norepinephrine; Parasympathetic Nervous System; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sympathetic Nervous System; Synaptic Transmission; Synaptic Vesicles; Yohimbine | 1993 |
The alpha-2 antagonists idazoxan and rauwolscine but not yohimbine or piperoxan are anxiolytic in the Vogel lick-shock conflict paradigm following intravenous administration.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clonidine; Conflict, Psychological; Dioxanes; Drinking Behavior; GABA Antagonists; Idazoxan; Infusions, Intravenous; Male; Piperoxan; Rats; Rats, Sprague-Dawley; Yohimbine | 1994 |
Receptor mechanisms for clonidine reversal of bupivacaine-induced impairment of ventricular conduction in pentobarbital-anesthetized dogs.
Topics: Animals; Bupivacaine; Carbachol; Clonidine; Dogs; Electrophysiology; Female; Ganglionic Blockers; Heart Conduction System; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Male; Nicotine; Pancuronium; Physostigmine; Receptors, Nicotinic; Yohimbine | 1994 |
Different sensitivity of alpha 2A-C10 and alpha 2C-C4 receptor subtypes in coupling to inhibition of cAMP accumulation.
Topics: Adenine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Clonidine; Colforsin; Cyclic AMP; Fibroblasts; Humans; Imidazoles; Kinetics; Medetomidine; Norepinephrine; Receptors, Adrenergic, alpha-2; Tetradecanoylphorbol Acetate; Transfection; Yohimbine | 1994 |
An alpha-adrenoceptor-mediated mechanism of hypoactivity induced by beta-amyrin palmitate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apomorphine; Clonidine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Motor Activity; Oleanolic Acid; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Triterpenes; Yohimbine | 1993 |
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Benzazepines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Functional Laterality; Idazoxan; Infusions, Parenteral; Kindling, Neurologic; Male; Rats; Receptors, Adrenergic, alpha-2; Seizures; Xylazine; Yohimbine | 1993 |
Clonidine enhances astrocytic glutamine uptake by authentic alpha 2-adrenoceptor stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Astrocytes; Cells, Cultured; Clonidine; Dioxanes; Glutamine; Idazoxan; Mice; Receptors, Adrenergic, alpha; Serotonin; Structure-Activity Relationship; Yohimbine | 1994 |
Effects of medetomidine on intestinal and colonic motility in the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Colon; Dogs; Drug Interactions; Electrophysiology; Gastrointestinal Motility; Hypnotics and Sedatives; Imidazoles; Injections, Intravenous; Jejunum; Medetomidine; Yohimbine | 1994 |
Amygdaloid noradrenaline is involved in the sensitization of the acoustic startle response in rats.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Amygdala; Animals; Clonidine; Dose-Response Relationship, Drug; Electroshock; Injections; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex, Startle; Yohimbine | 1994 |
New insights into receptor theory, as provided by an artificial partial agonist made-to-measure.
Topics: Animals; Autoreceptors; Brain; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Norepinephrine; Rabbits; Rats; Regression Analysis; Yohimbine | 1994 |
Alpha-adrenergic receptors mediate imipramine/alarm substance-induced reaction in rats.
Topics: Animals; Arousal; Brain; Citalopram; Clonidine; Dose-Response Relationship, Drug; Imipramine; Male; Norepinephrine; Nortriptyline; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, GABA; Reserpine; Serotonin; Yohimbine | 1994 |
Role of lateral preoptic area alpha-1 and alpha-2 adrenoceptors in sleep-wakefulness and body temperature regulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Body Temperature Regulation; Circadian Rhythm; Clonidine; Electroencephalography; Electromyography; Electrooculography; Male; Methoxamine; Microinjections; Prazosin; Preoptic Area; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sleep; Time Factors; Wakefulness; Yohimbine | 1994 |
Effects of neonatal exposure to clonidine on basal and activated central noradrenaline metabolism and in vivo overflow.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Clonidine; Dialysis; Dioxanes; Idazoxan; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Weight Gain; Yohimbine | 1994 |
In vitro study of the effect of clonidine on human umbilical artery motility.
Topics: Clonidine; Humans; In Vitro Techniques; Infant, Newborn; Methyldopa; Umbilical Arteries; Vasoconstriction; Yohimbine | 1994 |
Somatostatin receptors coupled to the inhibition of adenylyl cyclase in the rat frontoparietal cortex are modulated by alpha 2 adrenoceptors.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Catalysis; Clonidine; Frontal Lobe; GTP-Binding Proteins; Parietal Lobe; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Somatostatin; Somatostatin; Virulence Factors, Bordetella; Yohimbine | 1994 |
Functional influence of the central noradrenergic system on the skin conductance activity in rats.
Topics: Acoustic Stimulation; Animals; Arousal; Attention; Brain; Clonidine; Galvanic Skin Response; Habituation, Psychophysiologic; Injections, Intramuscular; Norepinephrine; Rats; Rats, Inbred F344; Yohimbine | 1994 |
Characterization of imidazoline binding protein(s) solubilized from human brainstem: studies with [3H]idazoxan and [3H]clonidine.
Topics: Binding Sites; Cell Membrane; Cholic Acids; Chromatography, Gel; Clonidine; Dioxanes; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Norepinephrine; Receptors, Drug; Solubility; Tritium; Yohimbine | 1994 |
Diaspirin cross-linked hemoglobin (DCLHB): involvement of adrenergic mechanisms in the pressor effect.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Aspirin; Blood Pressure; Blood Substitutes; Clonidine; Drug Interactions; Hemoglobins; Male; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1994 |
The effect of alpha 2-adrenoceptor antagonists in isolated globally ischemic rat hearts.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Coronary Circulation; Dioxanes; Heart; Heart Rate; Idazoxan; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tolazoline; Ventricular Pressure; Yohimbine | 1994 |
Effect of clonidine on induced cough and bronchoconstriction in guinea pigs and healthy humans.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adult; Airway Resistance; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Citrates; Citric Acid; Clonidine; Cough; Female; Guinea Pigs; Heart Rate; Humans; Male; Prazosin; Receptors, Adrenergic, alpha-2; Species Specificity; Yohimbine | 1994 |
Physiological and environmental aspects of drinking stimulated by chronic exposure to amphetamine in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Clonidine; Drinking; Drinking Behavior; Eating; Environment; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stereotyped Behavior; Stimulation, Chemical; Time Factors; Yohimbine | 1994 |
Agonist binding to alpha 2-adrenoceptors is elevated in the locus coeruleus from victims of suicide.
Topics: Adult; Aged; Aged, 80 and over; Autoradiography; Clonidine; Female; Humans; Iodine Radioisotopes; Locus Coeruleus; Male; Middle Aged; Norepinephrine; Receptors, Adrenergic, alpha-2; Reference Values; Suicide; Tritium; Yohimbine | 1994 |
Modifications by hypoxia and drug treatment of cerebral ATPase plasticity.
Topics: Adenosine Triphosphatases; Almitrine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cerebral Cortex; Clonidine; Hypoxia, Brain; Kinetics; Papaverine; Rats; Reference Values; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Synaptic Vesicles; Synaptosomes; Yohimbine | 1994 |
Clonidine has comparable effects on spontaneous sympathetic activity and afferent A delta and C-fiber-mediated somatosympathetic reflexes in dogs.
Topics: Animals; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Injections, Spinal; Kidney; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Neurons, Afferent; Reflex; Sympathetic Nervous System; Yohimbine | 1994 |
Anxiogenic-like effects of yohimbine and idazoxan in two behavioral situations in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Behavior, Animal; Choice Behavior; Clonidine; Conditioning, Classical; Conflict, Psychological; Dioxanes; Flumazenil; Idazoxan; Male; Mice; Yohimbine | 1993 |
In vivo noradrenaline release evoked in the anteroventral thalamic nucleus by locus coeruleus activation: an electrochemical study.
Topics: Animals; Axons; Clonidine; Desipramine; Electric Stimulation; Electrochemistry; Evoked Potentials; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Norepinephrine; Oxidation-Reduction; Pargyline; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thalamic Nuclei; Yohimbine | 1993 |
Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Body Temperature; Clonidine; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Pain Measurement; Prazosin; Yohimbine | 1993 |
Evidence for the presence of noradrenergic neurons and their inhibitory action on luteinizing hormone-releasing hormone release in cultured fetal rat hypothalamic cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Cells, Cultured; Clonidine; Female; Fetus; Gonadotropin-Releasing Hormone; Hypothalamus; Methyltyrosines; Neurons; Phenylephrine; Prazosin; Pregnancy; Rats; Rats, Sprague-Dawley; Yohimbine | 1993 |
Involvement of alpha 2-receptors in the analgesia induced by transient forebrain ischemia in rats.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain; Carotid Artery, Common; Clonidine; Dioxanes; Endorphins; Idazoxan; Ischemic Attack, Transient; Male; Methysergide; Naloxone; Norepinephrine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin; Synaptic Transmission; Yohimbine | 1993 |
Involvement of inhibitory dopamine-2 receptors in resting bradycardia in exercise-conditioned rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Bromocriptine; Clonidine; Female; Heart Rate; Metoclopramide; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Yohimbine | 1993 |
Effects of alpha 2- and beta-adrenergic agonism on glucagon secretion from perfused pancreata of normal and streptozocin-induced diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon; Glucose; Insulin; Insulin Secretion; Isoproterenol; Male; Norepinephrine; Pancreas; Propranolol; Radioimmunoassay; Rats; Rats, Wistar; Streptozocin; Yohimbine | 1993 |
Species-selective binding of [3H]-idazoxan to alpha 2-adrenoceptors and non-adrenoceptor, imidazoline binding sites in the central nervous system.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Central Nervous System; Cerebral Cortex; Clonidine; Dioxanes; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Humans; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Kinetics; Membranes; Mice; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, alpha; Receptors, Drug; Species Specificity; Yohimbine | 1993 |
Central alpha 2-adrenoceptor-mediated inhibition of gastric motility in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Stem; Clonidine; Gastrointestinal Motility; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Meperidine; Methoxydimethyltryptamines; Neurotransmitter Agents; Yohimbine | 1993 |
Alpha 1-adrenoceptors in the human prostatic urethra are different from those of the human peripheral arteries.
Topics: Arteries; Atropine; Clonidine; Dioxanes; Humans; Iliac Artery; Isometric Contraction; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Urethra; Yohimbine | 1993 |
Characterization of alpha 2-adrenoceptor binding sites in rabbit ciliary body membranes.
Topics: Affinity Labels; Animals; Binding, Competitive; Cell Membrane; Ciliary Body; Clonidine; Iodine Radioisotopes; Ligands; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-2; Sympathomimetics; Yohimbine | 1994 |
Effects of imidazolines on noradrenaline release in rat isolated kidney.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Electric Stimulation; Imidazoles; In Vitro Techniques; Isoindoles; Kidney; Male; Nordefrin; Norepinephrine; Rats; Rats, Wistar; Stimulation, Chemical; Sympathetic Nervous System; Yohimbine | 1994 |
Effects of subchronic exposure of rats to lead or zinc on alpha-adrenoceptor-mediated contractile responses in isolated vas deferens.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Lead; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Sulfates; Vas Deferens; Verapamil; Yohimbine; Zinc Compounds; Zinc Sulfate | 1993 |
Age-related changes in norepinephrine release and its modulation by presynaptic alpha-2 adrenoceptors in the rat vas deferens.
Topics: Aging; Animals; Clonidine; Electric Stimulation; Epididymis; Estradiol; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Potassium; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Synaptic Membranes; Vas Deferens; Yohimbine | 1993 |
Central histaminergic mechanisms in the corticosterone response to clonidine.
Topics: Animals; Brain; Clonidine; Corticosterone; Histamine; Histamine Antagonists; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Methylhistidines; Pituitary-Adrenal System; Rats; Rats, Wistar; Yohimbine | 1993 |
Involvement of alpha-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
[Effects of pressor area of ventral surface of medulla oblongata on the vasotonicity of renal vessels of rats].
Topics: Animals; Blood Pressure; Carotid Artery, Common; Clonidine; Electric Stimulation; Male; Medulla Oblongata; Rats; Rats, Wistar; Renal Artery; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1993 |
Comparison of the effects of T-1815, yohimbine and naloxone on mouse colonic propulsion.
Topics: Administration, Oral; Animals; Clonidine; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Loperamide; Male; Mice; Naloxone; Propylamines; Thiophenes; Yohimbine | 1993 |
Comparison of the effects of yohimbine and clonidine on the behaviour of female mice during social encounters in an "approach-avoidance" situation.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Escape Reaction; Female; Male; Mice; Motor Activity; Social Behavior; Yohimbine | 1993 |
Induction of cell expansion of goldfish melanocytoma cells (GMM-1) by epinephrine and dexamethasone requires external calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Line; Cell Size; Clonidine; Colforsin; Dexamethasone; Diglycerides; Egtazic Acid; Epinephrine; Goldfish; Melanoma; Nifedipine; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine | 1993 |
Analgesic effect of morphine, clonidine and serotonin microinjected into the PTN of rats.
Topics: Analgesics; Animals; Clonidine; Male; Methysergide; Microinjections; Morphine; Naloxone; Pain Measurement; Rats; Serotonin; Superior Colliculi; Yohimbine | 1993 |
Naloxone potentiation of novelty-induced hypoalgesia: characterization of the alpha-noradrenergic receptor subtype.
Topics: Animals; Clonidine; Drug Synergism; Habituation, Psychophysiologic; Male; Naloxone; Pain; Phentolamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Interaction between the alpha 2-adrenergic system and nursing in the regulation of growth hormone secretion in the neonatal rat.
Topics: Analysis of Variance; Animals; Animals, Suckling; Clonidine; Dose-Response Relationship, Drug; Growth Hormone; Radioimmunoassay; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Alpha 2- and beta-adrenergic stimulation of corticosterone secretion in rats.
Topics: Animals; Clonidine; Corticosterone; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1993 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine | 1993 |
Role of vascular alpha-2 adrenoceptors in regulating lipid mobilization from human adipose tissue.
Topics: Adipose Tissue; Adult; Analysis of Variance; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Ethanol; Female; Glycerol; Humans; Hydralazine; Kinetics; Labetalol; Lipid Mobilization; Male; Nitroprusside; Propranolol; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1993 |
The alpha 2A-adrenergic receptor is targeted directly to the basolateral membrane domain of Madin-Darby canine kidney cells independent of coupling to pertussis toxin-sensitive GTP-binding proteins.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Clonidine; Dogs; GTP-Binding Proteins; Immunohistochemistry; Iodine Radioisotopes; Kidney; Membrane Proteins; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pertussis Toxin; Radioligand Assay; Receptors, Adrenergic, beta; Sulfur Radioisotopes; Transfection; Tritium; Virulence Factors, Bordetella; Yohimbine | 1993 |
Alpha 2-adrenergic inhibition of Cl- transport by opercular epithelium is mediated by intracellular Ca2+.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Calcium; Calcium-Transporting ATPases; Chlorides; Clonidine; Dose-Response Relationship, Drug; Epithelium; Flavanones; Flavonoids; Gills; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Isoproterenol; Killifishes; Kinetics; Masoprocol; Pertussis Toxin; Phenylephrine; Receptors, Adrenergic, alpha; Terpenes; Thapsigargin; Virulence Factors, Bordetella; Yohimbine | 1993 |
Alpha 2-adrenoceptor modulation of A1 noradrenergic neuron input to supraoptic vasopressin cells.
Topics: Animals; Clonidine; Electric Stimulation; Male; Medulla Oblongata; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha; Supraoptic Nucleus; Vasopressins; Yohimbine | 1993 |
Effect of naringin and naringenin on contractions induced by noradrenaline in rat vas deferens--I. Evidence for postsynaptic alpha-2 adrenergic receptor.
Topics: Animals; Clonidine; Flavanones; Flavonoids; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Synapses; Vas Deferens; Yohimbine | 1993 |
Postnatal development of central nervous alpha 2-adrenergic binding sites: an in vitro autoradiography study in the tree shrew.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Clonidine; Iodine Radioisotopes; Kinetics; Receptors, Adrenergic, alpha-2; Tupaia; Yohimbine | 1993 |
Renal nerves are involved in the natriuresis and diuresis produced by central administration of clonidine in the rat.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Clonidine; Denervation; Diuresis; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Infusions, Intravenous; Infusions, Parenteral; Kidney; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Urine; Yohimbine | 1993 |
Heterogeneity of the specific imidazoline binding of [3H]idazoxan in the human cerebral cortex.
Topics: Binding Sites; Brain Stem; Cell Membrane; Cerebral Cortex; Clonidine; Dioxanes; Frontal Lobe; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Kinetics; Magnesium Chloride; Tritium; Yohimbine | 1993 |
Potentiation of dark onset feeding in obese mice (genotype ob/ob) following central injection of norepinephrine and clonidine.
Topics: Animals; Clonidine; Darkness; Feeding Behavior; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Norepinephrine; Phenotype; Propranolol; Stereotaxic Techniques; Yohimbine | 1993 |
Effects of noradrenaline on the firing rate of vestibular neurons.
Topics: Action Potentials; Animals; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Eye Movements; Iontophoresis; Isoproterenol; Male; Movement; Neurons; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Wistar; Vestibular Nuclei; Vestibule, Labyrinth; Yohimbine | 1993 |
Mechanism of insulin secretion by midaglizole.
Topics: Animals; Blood Glucose; Clonidine; Diazoxide; Dogs; Dose-Response Relationship, Drug; Glucagon; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Secretion; Kinetics; Time Factors; Yohimbine | 1993 |
Hypotensive action of 5-HT receptor agonists in the vitamin B6-deficient hypertensive rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Riboflavin Deficiency; Serotonin; Serotonin Receptor Agonists; Yohimbine | 1993 |
Concentrations of noradrenaline at neuronal uptake sites during sympathetic nervous inhibition and activation in rabbits.
Topics: Animals; Clonidine; Male; Methoxyhydroxyphenylglycol; Neurons; Nitroprusside; Norepinephrine; Rabbits; Sympathetic Nervous System; Yohimbine | 1993 |
Genesis of biphasic thermal response to intrapreoptically microinjected clonidine.
Topics: Animals; Body Temperature; Clonidine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Microinjections; Preoptic Area; Prostaglandin-Endoperoxide Synthases; Stereotaxic Techniques; Yohimbine | 1993 |
Apraclonidine protection of the blood-aqueous barrier from traumatic break-down.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Blood-Aqueous Barrier; Capillary Permeability; Clonidine; Coloring Agents; Evans Blue; Eye Proteins; Female; Intraocular Pressure; Iris; Laser Therapy; Male; Ophthalmic Solutions; Piperazines; Pupil; Rabbits; Triazoles; Yohimbine | 1995 |
Complex stimulus properties of LSD: a drug discrimination study with alpha 2-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Lysergic Acid Diethylamide; Male; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Action of dexmedetomidine on rat locus coeruleus neurones: intracellular recording in vitro.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Barium Compounds; Cesium; Chlorides; Clonidine; Electrophysiology; Imidazoles; In Vitro Techniques; Locus Coeruleus; Male; Medetomidine; Membrane Potentials; Neurons; Oxymetazoline; Parasympathetic Fibers, Postganglionic; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
The prejunctional inhibitory effect of alpha-methylnoradrenaline in the rat vas deferens is not mediated via alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Imidazoles; Isometric Contraction; Male; Neuromuscular Junction; Nordefrin; Phenoxybenzamine; Phentolamine; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Vasoconstrictor Agents; Yohimbine | 1995 |
MR-14134, a new benzothiazepine with central hypotensive action.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Clonidine; Decerebrate State; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Injections, Intraventricular; Male; Rats; Rats, Wistar; Yohimbine | 1995 |
Intrathecal clonidine and tizanidine in conscious dogs: comparison of analgesic and hemodynamic effects.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Blood Pressure; Bradycardia; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; Glycopyrrolate; Heart Rate; Hemodynamics; Idazoxan; Imidazoles; Injections, Spinal; Male; Parasympatholytics; Reaction Time; Sympatholytics; Vagus Nerve; Vasoconstrictor Agents; Wakefulness; Yohimbine | 1996 |
Role of external and internal calcium on heterocarrier-mediated transmitter release.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Carrier Proteins; Chelating Agents; Choline; Clonidine; Dopamine; Dopamine Agonists; Egtazic Acid; Ergolines; GABA Modulators; Hippocampus; Male; Muscarinic Agonists; Neostriatum; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Norepinephrine; Oxotremorine; Piperidines; Presynaptic Terminals; Quinpirole; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium; Yohimbine | 1996 |
A re-evaluation of the role of alpha 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlordiazepoxide; Clonidine; Dioxanes; Diphenhydramine; Hypnotics and Sedatives; Idazoxan; Imidazoles; Injections, Subcutaneous; Isoquinolines; Male; Maze Learning; Mydriasis; Naphthyridines; Picrotoxin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Influence of adrenoceptor agonists and antagonists on fluid secretion in small bowel obstruction.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Albuterol; Analysis of Variance; Animals; Body Water; Clonidine; Intestinal Obstruction; Intestine, Small; Jejunal Diseases; Male; Metoprolol; Phenylephrine; Prazosin; Prenalterol; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dose-Response Relationship, Drug; Heart Failure; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arginine; Capsaicin; Clonidine; Male; Mice; Nitroarginine; Pain; Phenylephrine; Plant Extracts; Prazosin; Yohimbine | 1995 |
Unusual alpha-adrenoceptor subtype in canine saphenous vein: comparison to mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dogs; Female; Humans; In Vitro Techniques; Male; Mesenteric Veins; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Adrenergic, alpha; Saphenous Vein; Yohimbine | 1996 |
Interactions of the cardiac chronotropic effects of rilmenidine with the autonomic nervous system in conscious dogs: comparison with clonidine.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Chronic Disease; Clonidine; Depression, Chemical; Dogs; Female; Heart Block; Heart Rate; Male; Muscarinic Antagonists; Oxazoles; Phenoxybenzamine; Pindolol; Rilmenidine; Yohimbine | 1996 |
Mianserin markedly and selectively increases extracellular dopamine in the prefrontal cortex as compared to the nucleus accumbens of the rat.
Topics: Animals; Clonidine; Dopamine; Dose-Response Relationship, Drug; Male; Mianserin; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 1996 |
Inhibition of alpha1-adrenoceptor-mediated contractions in isolated tail arteries and aorta of the rat by alpha2-adrenoceptor agonists.
Topics: Acetylcholine; Animals; Aorta; Arteries; Clonidine; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Tail; Yohimbine | 1995 |
5-hydroxytryptaminergic receptor-mediated regulation of growth hormone secretion in Holstein steers occurs via alpha 2-adrenergic-dependent and -independent mechanisms.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Cyproheptadine; Dioxanes; Growth Hormone; Growth Hormone-Releasing Hormone; Idazoxan; Imidazoles; In Vitro Techniques; Male; Pituitary Gland, Anterior; Quipazine; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 1996 |
Involvement of alpha-2 adrenoceptors in the periaqueductal gray-induced inhibition of dorsal horn cell activity in rats.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Ganglia, Spinal; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 1996 |
Altered thermoregulatory responses to clonidine in streptozotocin-diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature Regulation; Clonidine; Diabetes Mellitus, Experimental; Idazoxan; Male; Rats; Rats, Wistar; Streptozocin; Time Factors; Yohimbine | 1996 |
Antinociceptive effects of oral clonidine and S12813-4 in acute colon inflammation in rats.
Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Colitis; Female; Formaldehyde; Idazoxan; Oxazoles; Rats; Rats, Sprague-Dawley; Yohimbine | 1996 |
Cardiovascular responses to static exercise in conscious cats: effects of intracerebroventricular injection of clonidine.
Topics: Animals; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Injections, Spinal; Physical Conditioning, Animal; Time Factors; Yohimbine | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
alpha-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Prazosin; Receptors, Opioid; Yohimbine | 1996 |
Effects of clonidine, yohimbine and idazoxan on isolated carotid arteries of dog.
Topics: Animals; Carotid Arteries; Clonidine; Dogs; Idazoxan; In Vitro Techniques; Muscle, Smooth, Vascular; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1996 |
Effect of phenylethanolamine N-methyltransferase inhibitor, CGS19281A, on the alpha-2-adrenoceptor function in the hypothalamus of rats in comparison with SKF29661, SKF64139 and yohimbine.
Topics: Animals; Carbolines; Clonidine; Hypothalamus; Isoquinolines; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Tetrahydroisoquinolines; Yohimbine | 1996 |
Norepinephrine attenuates serotonin inhibition of pial venous tone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Veins; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Male; Methoxamine; Norepinephrine; Pertussis Toxin; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Swine; Thromboxane A2; Vasoconstriction; Virulence Factors, Bordetella; Yohimbine | 1996 |
Yohimbine as an antidote for clonidine overdose.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Antidotes; Clonidine; Drug Overdose; Female; Humans; Yohimbine | 1996 |
[The in vitro effect of alpha-2 agonists on thrombocyte function and density of thrombocyte alpha-2 receptors].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Blood Platelets; Clonidine; Humans; Imidazoles; In Vitro Techniques; Medetomidine; Phentolamine; Platelet Aggregation; Radioligand Assay; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
Neuropeptide Y levels in the aqueous humor of rabbits.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Circadian Rhythm; Clonidine; Ganglia, Sympathetic; Ganglionectomy; Male; Neuropeptide Y; Rabbits; Sympathectomy; Yohimbine | 1996 |
Synergistic behavioral interaction between ethanol and clonidine in rats: role of alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Blood Pressure; Clonidine; Drug Synergism; Ethanol; Idazoxan; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reflex; Yohimbine | 1996 |
Presynaptic imidazoline receptors and alpha 2-adrenoceptors in the human heart: discrimination by clonidine and moxonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Humans; Imidazoles; In Vitro Techniques; Isoindoles; Male; Middle Aged; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1996 |
Hypoxia/reoxygenation selectively impairs alpha 1b-adrenoceptor function in small mesenteric arteries.
Topics: Adrenergic alpha-Antagonists; Aerobiosis; Animals; Catalase; Clonidine; Dioxanes; Hypoxia; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Superoxide Dismutase; Yohimbine | 1996 |
Insulin-dependent attenuation in alpha 2-adrenoreceptor-mediated nociception in experimental diabetes.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Body Weight; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Hypoglycemic Agents; Insulin; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 1997 |
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine | 1997 |
Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Conscious Sedation; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Feeding Behavior; Imidazoles; Injections, Intraventricular; Male; Medetomidine; Methoxamine; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
On a dual role for clonidine stimulation of the ventromedial nucleus of the hypothalamus in sodium and potassium renal excretions of rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Hypothalamus; Kidney; Male; Potassium; Prazosin; Rats; Sodium; Yohimbine | 1996 |
Effects of alpha-adrenergic agonists on Toxoplasma gondii replication in human umbilical vein endothelial cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Endothelium, Vascular; Guanabenz; Humans; In Vitro Techniques; Methoxamine; Nitrogen Dioxide; Toxoplasma; Umbilical Veins; Yohimbine | 1997 |
Binding of new cirazoline derivative to imidazoline receptors from human brain.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Brain; Clonidine; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Mitochondria; Photochemistry; Rabbits; Rats; Receptors, Drug; Tritium; Ultraviolet Rays; Yohimbine | 1997 |
Evidence of the involvement of biogenic amines in the antinociceptive effect of a vouacapan extracted from Pterodon polygalaeflorus Benth.
Topics: Analgesics, Non-Narcotic; Animals; Brazil; Clonidine; Diterpenes; Domperidone; Dopamine; Guanethidine; Male; Mice; Plant Extracts; Plants, Medicinal; Yohimbine | 1996 |
Differential effects of clonidine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Transit; Imidazoles; Male; Medetomidine; Morphine; Naloxone; Rats; Rats, Wistar; Yohimbine | 1997 |
The effect of the putative endogenous imidazoline receptor ligand, clonidine-displacing substance, on insulin secretion from rat and human islets of Langerhans.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Brain; Clonidine; Humans; Imidazoline Receptors; Insulin; Insulin Secretion; Islets of Langerhans; Ligands; Male; Potassium; Rats; Rats, Wistar; Receptors, Drug; Sodium; Yohimbine | 1997 |
Effects of moxonidine and clonidine on renal function and blood pressure in anesthetized rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Glomerular Filtration Rate; Idazoxan; Imidazoles; Kidney; Male; Plasma Volume; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium; Water-Electrolyte Balance; Yohimbine | 1997 |
Inhibition of contractions by tricyclic antidepressants and xylamine in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Barium Compounds; Calcium; Chlorides; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Nitrogen Mustard Compounds; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Vas Deferens; Yohimbine | 1997 |
Clonidine inhibits gastric motility in the rat.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Gastric Emptying; Male; Naloxone; Rats; Rats, Wistar; Yohimbine | 1997 |
Mivazerol, a new alpha 2-adrenergic agonist, blunts cardiovascular effects following surgical stress in pentobarbital-anesthetized rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Clonidine; Heart Rate; Imidazoles; Medetomidine; Pentobarbital; Rats; Rats, Sprague-Dawley; Stress, Physiological; Surgical Procedures, Operative; Yohimbine | 1997 |
Cardiovascular effects of central administration of clonidine in conscious cats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Behavior, Animal; Benzofurans; Blood Pressure; Cardiovascular System; Cats; Cimetidine; Clonidine; Coloring Agents; Consciousness; Dose-Response Relationship, Drug; Evans Blue; Female; Heart Rate; Histamine H2 Antagonists; Imidazoles; Injections, Intraventricular; Yohimbine | 1997 |
The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal.
Topics: Adrenergic Agents; Animals; Clonidine; Drug Interactions; Idazoxan; Male; Mice; Morphine; Narcotics; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Yohimbine | 1997 |
Antinociceptive interaction of intrathecal alpha2-adrenergic agonists, tizanidine and clonidine, with lidocaine in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Injections, Spinal; Lidocaine; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
Blink reflex to supraorbital nerve stimulation in the cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blinking; Cats; Clonidine; Conditioning, Psychological; Electric Stimulation; Electromyography; Habituation, Psychophysiologic; Male; Ophthalmic Nerve; Reaction Time; Yohimbine | 1997 |
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1997 |
Involvement of alpha2-adrenoceptors in mediating sympathetic excitation of injured dorsal root ganglion neurons in rats with spinal nerve ligation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Ganglia, Spinal; Ligation; Male; Neurons; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Nerves; Yohimbine | 1997 |
[Influence of microinjection of clonidine and yohimbine in rVLM on the effect of electroacupuncture treatment of myocardial ischemia].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Electroacupuncture; Female; Male; Medulla Oblongata; Microinjections; Myocardial Ischemia; Rabbits; Yohimbine | 1996 |
Characterization of alpha-adrenoceptors in canine mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dogs; Female; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 1997 |
Alprazolam, diazepam, yohimbine, clonidine: in vivo CA1 hippocampal norepinephrine and serotonin release profiles under chloral hydrate anesthesia.
Topics: Adrenergic alpha-Antagonists; Alprazolam; Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Anxiety; Chloral Hydrate; Clonidine; Diazepam; Hippocampus; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Yohimbine | 1997 |
Renal and blood pressure effects of moxonidine and clonidine in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Aminoacridines; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Idazoxan; Imidazoles; Kidney; Male; Phenformin; Rats; Rats, Inbred SHR; Sodium; Urodynamics; Yohimbine | 1997 |
A role for amino acid residues in the third cytoplasmic loop in defining the ligand binding characteristics of the alpha2D-adrenergic receptor.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Clonidine; COS Cells; Cytoplasm; Epinephrine; Humans; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxymetazoline; Phentolamine; Prazosin; Protein Binding; Rats; Receptors, Adrenergic, alpha-2; Sequence Alignment; Yohimbine | 1997 |
Omega-conotoxin GVIA-resistant neurotransmitter release from postganglionic sympathetic nerves in the guinea-pig vas deferens and its modulation by presynaptic receptors.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dinoprostone; Guinea Pigs; In Vitro Techniques; Male; Mice; Neuropeptide Y; Neurotransmitter Agents; omega-Conotoxin GVIA; Peptides; Receptors, Adrenergic, alpha-2; Sympathetic Fibers, Postganglionic; Vas Deferens; Yohimbine | 1998 |
The vascular effects of topical and intravenous alpha2-adrenoceptor agonist clonidine on canine pial microcirculation.
Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Blood Glucose; Cerebrovascular Circulation; Clonidine; Craniotomy; Dogs; Dose-Response Relationship, Drug; Glyburide; Heart Rate; Injections, Intravenous; Microcirculation; Pentobarbital; Pia Mater; Potassium; Potassium Channel Blockers; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Vasodilator Agents; Veins; Yohimbine | 1998 |
Post- and presynaptic effects of norepinephrine in guinea-pig colonic submucous plexus.
Topics: Acetylcholine; Animals; Clonidine; Colon; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Microelectrodes; Muscle, Smooth; Myenteric Plexus; Neurons; Norepinephrine; Phentolamine; Prazosin; Synapses; Yohimbine | 1998 |
Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Behavior, Animal; Bromocriptine; Clonidine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Levodopa; Lisuride; Locomotion; Male; Mazindol; Methoxydimethyltryptamines; Oxidopamine; Parkinson Disease, Secondary; Prosencephalon; Rats; Rats, Sprague-Dawley; Sympatholytics; Tritium; Yohimbine | 1998 |
The role of alpha-2 receptors in the medial preoptic area in the regulation of sleep-wakefulness and body temperature.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents; Body Temperature; Clonidine; Dimethyl Sulfoxide; Electroencephalography; Electromyography; Electrooculography; Male; Norepinephrine; Preoptic Area; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rectum; Sleep; Sodium Chloride; Wakefulness; Yohimbine | 1998 |
Clonidine and vasomotion physiology.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Cattle; Clonidine; Drug Synergism; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Yohimbine | 1998 |
Passive avoidance learning involves alpha2-noradrenergic receptors in a day old chick.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Autoradiography; Avoidance Learning; Chickens; Clonidine; Functional Laterality; Injections, Intraventricular; Prosencephalon; Receptors, Adrenergic, alpha-2; Yohimbine | 1998 |
Noradrenergic modulation of methamphetamine-induced striatal dopamine depletion.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzylamines; Cell Count; Clonidine; Corpus Striatum; Dopamine; Dopamine Agents; Drug Combinations; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Norepinephrine; Rats; Rats, Sprague-Dawley; Yohimbine | 1998 |
Autonomic nervous control of venous pressure and secretion in submandibular gland of anesthetized dogs.
Topics: Acetylcholine; Anesthesia, General; Animals; Arteries; Autonomic Nervous System; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Isoproterenol; Jugular Veins; Male; Parasympathetic Nervous System; Phenobarbital; Phentolamine; Phenylephrine; Prazosin; Propranolol; Pulse; Regional Blood Flow; Saliva; Submandibular Gland; Vasoactive Intestinal Peptide; Veins; Yohimbine | 1998 |
Chloroethylclonidine is a partial alpha1-adrenoceptor agonist in aorta and caudal arteries of the Wistar Kyoto rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 1998 |
Prejunctional alpha2-adrenoceptors and peroxide-induced potentiation of norepinephrine release from the bovine iris.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Brimonidine Tartrate; Cattle; Clonidine; Culture Techniques; Hydrogen Peroxide; Iris; Neuroeffector Junction; Norepinephrine; Oxymetazoline; Perfusion; Quinoxalines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Tritium; Yohimbine | 1998 |
Effects of drugs acting on adrenergic and adenosine receptors on the intraocular pressure and the activity of adenylyl cyclase in ciliary processes and their sensitivity to pertussis toxin.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Ciliary Body; Clonidine; Epinephrine; Fenoterol; Intraocular Pressure; Pertussis Toxin; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Adrenergic; Receptors, Purinergic P1; Virulence Factors, Bordetella; Yohimbine | 1997 |
The influence of pH alteration and pharmacological modulators of adenylate cyclase system on human serum albumin conformation.
Topics: Adenylyl Cyclases; Carbachol; Clonidine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Propranolol; Protein Conformation; Serum Albumin; Theophylline; Yohimbine | 1998 |
The antinociceptive effect of moclobemide in mice is mediated by noradrenergic pathways.
Topics: Analgesics; Animals; Benzamides; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Injections, Spinal; Injections, Subcutaneous; Male; Metergoline; Mice; Mice, Inbred ICR; Moclobemide; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Neural Pathways; Norepinephrine; Receptors, Adrenergic, alpha-2; Serotonin; Yohimbine | 1998 |
Platelet and brain alpha 2-adrenoceptors and cardiovascular sensitivity to agonists in dogs suffering from endotoxic shock.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Platelets; Brain; Catecholamines; Cerebral Cortex; Clonidine; Dogs; Endotoxins; Female; Male; Medulla Oblongata; Receptors, Adrenergic, alpha-2; Shock, Septic; Xylazine; Yohimbine | 1998 |
Study of human serum albumin structure by dynamic light scattering: two types of reactions under different pH and interaction with physiologically active compounds.
Topics: Atropine; Carbachol; Chlorpromazine; Clonidine; Diphenhydramine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phenylephrine; Propranolol; Protein Binding; Scattering, Radiation; Serum Albumin; Yohimbine | 1998 |
Cardiovascular effects of intravenous administration of clonidine in conscious cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Cimetidine; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Histamine H2 Antagonists; Injections, Intravenous; Injections, Intraventricular; Yohimbine | 1998 |
Pharmacological evidence for different alpha 2-adrenergic receptor sites mediating analgesia and sedation in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics, Non-Narcotic; Animals; Brimonidine Tartrate; Clonidine; Conscious Sedation; Hypnotics and Sedatives; Imidazoles; Injections, Intraventricular; Injections, Spinal; Male; Medetomidine; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 1998 |
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonidine Tartrate; Cell Count; Cell Survival; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Retinal Ganglion Cells; Timolol; Yohimbine | 1999 |
Modulation of relative intrinsic activity of agonists at the alpha-2A adrenoceptor by mutation of residue 351 of G protein gi1alpha.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; COS Cells; Cysteine; Dose-Response Relationship, Drug; Epinephrine; Glycine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Point Mutation; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Swine; Yohimbine | 1999 |
The effect of alpha2-adrenergic drugs on the activity of neurons in the rat nucleus raphe magnus in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Stem; Clonidine; Dose-Response Relationship, Drug; Neural Inhibition; Neural Pathways; Neurons; Nociceptors; Pain; Raphe Nuclei; Rats; Rats, Wistar; Synaptic Transmission; Yohimbine | 1999 |
Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonidine; Drug Interactions; Lidocaine; Male; Mice; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-2; Seizures; Time Factors; Yohimbine | 1999 |
Inhibition of stress-stimulated colonic propulsion by alpha 2-adrenoceptor antagonists in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Colon; Defecation; Gastrointestinal Motility; Gastrointestinal Transit; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stress, Physiological; Yohimbine | 1998 |
Effects of clonidine on myocardial beta-adrenergic receptor-adenyl cyclase-cAMP system after scalds in rats.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Burns; Clonidine; Cyclic AMP; Male; Myocardium; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Yohimbine | 1997 |
Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Carotid Arteries; Clonidine; Dihydroergotamine; Dogs; Ergotamine; Female; Hemodynamics; Male; Methysergide; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 1999 |
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine | 1998 |
Recovery of locomotion after ventral and ventrolateral spinal lesions in the cat. II. Effects of noradrenergic and serotoninergic drugs.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Clonidine; Denervation; Electromyography; Free Radical Scavengers; Locomotion; Methoxamine; Norepinephrine; Quipazine; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Sympatholytics; Sympathomimetics; Yohimbine | 1999 |
Sympathoinhibitory effects of clonidine are transmitted by the caudal ventrolateral medulla in cats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Infusions, Intravenous; Sympathetic Nervous System; Sympatholytics; Yohimbine | 1999 |
Noradrenergic responses of neurones in the mediolateral part of the lateral septum: alpha1-adrenergic depolarization and rhythmic bursting activities, and alpha2-adrenergic hyperpolarization from guinea pig brain slices.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Electrophysiology; Female; Guinea Pigs; Neurons; Nickel; Norepinephrine; Organ Culture Techniques; Periodicity; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Septal Nuclei; Sodium; Tetraethylammonium; Tetrodotoxin; Yohimbine | 1999 |
The effect of tizanidine on maximal electroshock seizures (MES) in mice.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Clonidine; Electroshock; Female; Injections, Intraperitoneal; Male; Mice; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine | 1999 |
Adrenergic sensitivity of the sensory receptors modulating mechanical allodynia in a rat neuropathic pain model.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Causalgia; Clonidine; Idazoxan; Male; Neurons, Afferent; Norepinephrine; Phenylephrine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Nerves; Sympathectomy; Sympathetic Nervous System; Yohimbine | 1999 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Preconditioning prevents the negative inotropic action of phenylephrine in rat isolated stunned papillary muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Cardiotonic Agents; Clonidine; Dioxanes; Female; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Muscle Contraction; Papillary Muscles; Phenylephrine; Rats; Rats, Wistar; Reperfusion Injury; Yohimbine | 1999 |
Coexpression of imidazoline receptors and alpha 2-adrenoceptors in neuroglial cell line NG 108,15.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Glioma; Hybrid Cells; Idazoxan; Imidazoline Receptors; Kinetics; Neuroblastoma; Neuroglia; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1999 |
Mechanism of the sympathoinhibition produced by the clonidine-like drugs rilmenidine and moxonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Clonidine; Decerebrate State; Heart Rate; Imidazoles; Injections, Spinal; Medulla Oblongata; Microinjections; Oxazoles; Rabbits; Rilmenidine; Sympathetic Nervous System; Yohimbine | 1999 |
Importance of imidazoline receptors in the cardiovascular responses of clonidine in sinoaortic denervated rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Clonidine; Denervation; Heart Rate; Heart Valves; Idazoxan; Imidazoline Receptors; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Drug; Sinus of Valsalva; Yohimbine | 1999 |
Alpha2 adrenergic and high affinity serotonergic receptor changes in the brain stem of streptozotocin-induced diabetic rats.
Topics: Affinity Labels; Animals; Binding, Competitive; Brain Stem; Chromatography, High Pressure Liquid; Clonidine; Diabetes Mellitus, Experimental; Epinephrine; Guanylyl Imidodiphosphate; Insulin; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin; Yohimbine | 1999 |
Neurochemical modulation of the P13 midlatency auditory evoked potential in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Auditory Cortex; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Evoked Potentials, Auditory; GABA Agonists; Habituation, Psychophysiologic; Male; Microinjections; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Reaction Time; Sleep; Yohimbine | 1999 |
Alpha2-adrenergic effect on human breast cancer MCF-7 cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Breast Neoplasms; Cell Division; Cells, Cultured; Clonidine; Cyclic AMP; Epinephrine; Female; Humans; Norepinephrine; Phentolamine; Prazosin; Propranolol; Tumor Cells, Cultured; Yohimbine | 1999 |
Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aged; Aging; Alzheimer Disease; Antimetabolites; Catechols; Chromatography, High Pressure Liquid; Clonidine; Cognition Disorders; Dihydroxyphenylalanine; Extracellular Space; Female; Humans; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Neurons; Neuropsychological Tests; Norepinephrine; Yohimbine | 1999 |
Alpha-2 adrenergic modulation of prefrontal cortical neuronal activity related to spatial working memory in monkeys.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Mapping; Clonidine; Electrooculography; Eye Movements; Female; Infusion Pumps, Implantable; Macaca mulatta; Memory; Neurons; Prefrontal Cortex; Psychomotor Performance; Reaction Time; Receptors, Adrenergic, alpha-2; Space Perception; Yohimbine | 1999 |
Mechanism of antinociceptive action of clonidine in nonmyelinated nerve fibres.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Analgesics; Anesthetics, Local; Animals; Clonidine; Electric Stimulation; Electrophysiology; In Vitro Techniques; Myelin Sheath; Nerve Fibers; Rabbits; Receptors, Adrenergic, alpha-2; Sodium Channels; Time Factors; Vagus Nerve; Yohimbine | 1999 |
Central benzodiazepine involvement in clonidine cardiovascular actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Carbolines; Cardiovascular Agents; Clonidine; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Heart Rate; Infusions, Intravenous; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Stereotaxic Techniques; Time Factors; Yohimbine | 1999 |
The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzofurans; Biogenic Monoamines; Clonidine; Disease Models, Animal; Drug Combinations; Drug Synergism; Locomotion; Male; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Prazosin; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reserpine; Yohimbine | 1999 |
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine | 2000 |
New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; CHO Cells; Clonidine; Cricetinae; Humans; Male; Prazosin; Pyridines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Xylazine; Yohimbine | 2000 |
The effect of D-amphetamine, clonidine, and yohimbine on human information processing.
Topics: Adult; Attention; Clonidine; Cognition; Dextroamphetamine; Electroencephalography; Evoked Potentials, Visual; Humans; Male; Psychomotor Performance; Reaction Time; Yohimbine | 1994 |
Effects of the I(1) imidazoline/alpha(2)-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Benzofurans; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imidazoles; Imidazoline Receptors; Injections, Subcutaneous; Male; Pain; Pain Measurement; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors; Yohimbine | 2000 |
Supraspinal, not spinal, alpha(2) adrenoceptors are involved in the anesthetic-sparing and hemodynamic-stabilizing effects of systemic clonidine in rats.
Topics: Adrenergic alpha-Agonists; Anesthetics; Animals; Brain; Clonidine; Hemodynamics; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2000 |
Coloanal motor coordination in association with high-amplitude colonic contractions after pharmacological stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Anal Canal; Clonidine; Colon; Defecation; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Humans; Male; Manometry; Muscle Relaxation; Reference Values; Reflex; Yohimbine | 2000 |
alpha2-adrenoceptor regulation of the hypothalamic-pituitary-adrenocortical axis in obesity.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Body Constitution; Case-Control Studies; Clonidine; Corticotropin-Releasing Hormone; Epinephrine; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Norepinephrine; Obesity; Pituitary-Adrenal System; Yohimbine | 2000 |
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Veins; Cerebrovascular Circulation; Clonidine; Dexmedetomidine; Hemodynamics; Hypercapnia; Hypoxia; Injections, Spinal; Pentobarbital; Rabbits; Vasodilation; Yohimbine | 2000 |
Neurotransmitter-mediated control of neuronal firing in the red nucleus of the rat: reciprocal modulation between noradrenaline and GABA.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bicuculline; Clonidine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Neurons; Neurotransmitter Agents; Nipecotic Acids; Norepinephrine; Rats; Rats, Wistar; Red Nucleus; Timolol; Yohimbine | 2000 |
Synthesis and alpha-adrenergic binding ligand affinities of 2-iminoimidazolidine derivatives.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Idazoxan; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Spectrophotometry, Infrared; Yohimbine | 2000 |
Coupling of I(1) imidazoline receptors to the cAMP pathway: studies with a highly selective ligand, benazoline.
Topics: Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic AMP; HT29 Cells; Humans; Imidazoles; Imidazoline Receptors; Ligands; PC12 Cells; Pertussis Toxin; Rats; Receptors, Adrenergic, alpha-2; Receptors, Drug; Virulence Factors, Bordetella; Yohimbine | 2000 |
Towards identifying optimal doses for alpha-2 adrenergic modulation of colonic and rectal motor and sensory function.
Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Clonidine; Colon; Colonic Diseases, Functional; Female; Gases; Gastrointestinal Motility; Humans; Male; Pain; Perception; Receptors, Adrenergic, alpha-2; Rectum; Yohimbine | 2000 |
Norepinephrine release from spinal synaptosomes: auto-alpha2 -adrenergic receptor modulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blotting, Western; Clonidine; Idazoxan; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Synaptosomes; Transfection; Yohimbine | 2000 |
Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; CHO Cells; Clonidine; Cloning, Molecular; COS Cells; Cricetinae; DNA, Complementary; Epinephrine; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Immune Sera; Iodine Radioisotopes; Molecular Sequence Data; Naphazoline; Receptors, Drug; Ruthenium Red; Sequence Tagged Sites; Staining and Labeling; Transfection; Yohimbine | 2000 |
Participation of alpha-1 and alpha-2 adrenoceptors of the lateral hypothalamic area in water intake, and renal sodium, potassium and urinary volume excretion induced by central administration of angiotensin II.
Topics: Angiotensin II; Animals; Clonidine; Drinking; Drug Administration Schedule; Drug Interactions; Hypothalamic Area, Lateral; Injections, Intraventricular; Kidney; Male; Neural Pathways; Neurons; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sodium; Subfornical Organ; Yohimbine | 2000 |
Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anxiety; Atropine; Clonidine; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Yohimbine | 2000 |
Initiating or blocking locomotion in spinal cats by applying noradrenergic drugs to restricted lumbar spinal segments.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Decerebrate State; Electric Stimulation; Electromyography; Female; Hindlimb; Injections, Intravenous; Locomotion; Lumbosacral Region; Male; Microinjections; Spinal Cord; Spinal Cord Injuries; Stimulation, Chemical; Yohimbine | 2000 |
The effects of noradrenaline and alpha-2 adrenoceptor agents on the production of monocytic products.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Clonidine; Female; Humans; Immune Tolerance; Immunosuppressive Agents; In Vitro Techniques; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Male; Middle Aged; Monocytes; Norepinephrine; Sialoglycoproteins; Stress, Psychological; Tumor Necrosis Factor-alpha; Yohimbine | 2000 |
Evidence for central alpha(2)-adrenergic modulation of rat pineal melatonin synthesis.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Circadian Rhythm; Clonidine; Male; Medetomidine; Melatonin; Pineal Gland; Quinolizines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Neuromuscular Junction; Oxymetazoline; Phentolamine; Pyridoxal Phosphate; Receptors, Adrenergic, alpha-2; Reserpine; Suramin; Yohimbine | 2001 |
Neural circuits regulating pulsatile luteinizing hormone release in the female guinea-pig: opioid, adrenergic and serotonergic interactions.
Topics: Animals; Clonidine; Drug Interactions; Female; Fentanyl; Gonadotropin-Releasing Hormone; Guinea Pigs; Luteinizing Hormone; Methysergide; Naloxone; Norepinephrine; Opioid Peptides; Ovariectomy; Periodicity; Quipazine; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 2001 |
Ultrasonic vocalizations of preweanling rats: involvement of both alpha(2)-adrenoceptor and kappa-opioid receptor systems.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Animals, Suckling; Clonidine; Female; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, kappa; Vocalization, Animal; Yohimbine | 2001 |
Alpha2 adrenergic receptors and the central control of breathing in the cane toad, Bufo marinus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Bufo marinus; Clonidine; Decerebrate State; Epinephrine; Medulla Oblongata; Norepinephrine; Receptors, Adrenergic, alpha-2; Respiratory Mechanics; Yohimbine | 2001 |
Clonidine-induced antinociception and locomotor hypoactivity are reduced by dexamethasone in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Clonidine; Cycloheximide; Dexamethasone; Male; Mice; Motor Activity; Pain Measurement; Protein Synthesis Inhibitors; Reaction Time; Yohimbine | 2001 |
Interaction of formamidine pesticides with the presynaptic alpha(2)-adrenoceptor regulating.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chlorphenamidine; Clonidine; Dose-Response Relationship, Drug; Female; Hypothalamus; Imidazoles; Indoles; Insecticides; Isoindoles; Norepinephrine; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Synaptosomes; Toluidines; Tritium; Xylazine; Yohimbine | 2001 |
Pharmacological aids to locomotor training after spinal injury in the cat.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Excitatory Amino Acid Antagonists; Locomotion; Recovery of Function; Spinal Cord Injuries; Sympatholytics; Yohimbine | 2001 |
Comparison of the effect of intrathecal administration of clonidine and yohimbine on the locomotion of intact and spinal cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Electric Stimulation; Electromyography; Gait; Injections, Spinal; Locomotion; Peroneal Nerve; Reflex; Spinal Cord Injuries; Yohimbine | 2001 |
Differential role of adrenoceptors in control of plasma glucose and fatty acids in carp, Cyprinus carpio (L.).
Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Carps; Clonidine; Epinephrine; Fatty Acids, Nonesterified; Isoproterenol; Lactic Acid; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Yohimbine | 2001 |
An obligatory role for spinal cholinergic neurons in the antiallodynic effects of clonidine after peripheral nerve injury.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Aziridines; Behavior, Animal; Choline; Clonidine; Immunohistochemistry; Male; Neurons; Neurotoxins; Parasympathetic Nervous System; Peripheral Nerve Injuries; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2001 |
An isobolographic analysis of the adrenergic modulation of diclofenac antinociception.
Topics: Adrenergic Agents; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Mice; Phenylephrine; Prazosin; Yohimbine | 2001 |
The role of Kupffer cell alpha(2)-adrenoceptors in norepinephrine-induced TNF-alpha production.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Kupffer Cells; Male; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tumor Necrosis Factor-alpha; Yohimbine | 2001 |
Alpha-2 and beta-adrenergic receptors mediate NE's biphasic effects on rat thick ascending limb chloride flux.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Chlorides; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Kidney Medulla; Loop of Henle; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Yohimbine | 2001 |
Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds; Brimonidine Tartrate; Calbindin 2; Cell Death; Choline O-Acetyltransferase; Clonidine; Electroretinography; Heptanes; Imidazoline Receptors; Immunohistochemistry; Membrane Potentials; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reperfusion Injury; Retina; Retinal Ganglion Cells; S100 Calcium Binding Protein G; Yohimbine | 2001 |
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alveolar Process; Animals; Arteries; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mandible; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction; Xylazine; Yohimbine | 2001 |
Alpha(2)-adrenergic-mediated tubular NO production inhibits thick ascending limb chloride absorption.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminoquinolines; Animals; Biological Transport; Chlorides; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Loop of Henle; Male; Nephrons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2001 |
Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholestasis; Clonidine; Disease Models, Animal; Male; Mice; Naloxone; Narcotic Antagonists; Opioid Peptides; Substance Withdrawal Syndrome; Yohimbine | 2001 |
Norepinephrine induces apoptosis in skin melanophores by attenuating cAMP-PKA signals via alpha2-adrenoceptors in the medaka, Oryzias latipes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apoptosis; Clonidine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Isoquinolines; Melanophores; Norepinephrine; Oligopeptides; Oryzias; Phenylephrine; Prazosin; Protein Isoforms; Receptors, Adrenergic, alpha-2; Signal Transduction; Skin; Skin Pigmentation; Sulfonamides; Yohimbine | 2001 |
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine | 2001 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine | 2001 |
A role for spinal, but not supraspinal, alpha(2) adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cimetidine; Clonidine; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2001 |
Effects of alpha- and beta-adrenergic stimulation on free magnesium concentrations in platelets from healthy and obese individuals.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Blood Platelets; Clonidine; Epinephrine; Humans; Insulin; Isoproterenol; Magnesium; Male; Norepinephrine; Obesity; Time Factors; Yohimbine | 2001 |
Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imipramine; Injections, Intraventricular; Male; Nociceptors; Pain; Pain Measurement; Prazosin; Rats; Rats, Wistar; Yohimbine | 2002 |
Intrathecal alpha2 adrenoceptor agonist clonidine inhibits mechanical transmission in mouse spinal cord via activation of muscarinic M1 receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Hot Temperature; Injections, Spinal; Male; Mechanoreceptors; Mice; Muscarinic Antagonists; Pain Measurement; Pain Threshold; Physical Stimulation; Reaction Time; Receptor, Muscarinic M1; Receptors, Muscarinic; Spinal Cord; Synaptic Transmission; Yohimbine | 2002 |
Inhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Neural Inhibition; Neurons; Prazosin; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Synapses; Synaptic Transmission; Yohimbine | 2002 |
Alpha-2 adrenoceptor activity affects propofol-induced sleep time.
Topics: Anesthetics, Intravenous; Animals; Clonidine; gamma-Aminobutyric Acid; Male; Norepinephrine; Prefrontal Cortex; Propofol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sleep; Yohimbine | 2002 |
The effects of simultaneous administration of alpha(2) -adrenergic agents with L-NAME or L-arginine on the development and expression of morphine dependence in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arginine; Clonidine; Enzyme Inhibitors; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Substance Withdrawal Syndrome; Yohimbine | 2002 |
Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Binding, Competitive; Brimonidine Tartrate; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Idazoxan; Middle Cerebral Artery; Norepinephrine; Phenylephrine; Pregnancy; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2002 |
Alpha2 -adrenoceptor function in arterial hypertension associated with obesity in dogs fed a high-fat diet.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Platelets; Blood Pressure; Catecholamines; Clonidine; Diastole; Dietary Fats; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Obesity; Prazosin; Receptors, Adrenergic, alpha; Systole; Yohimbine | 2002 |
Lithium inhibits the development of physical dependence to clonidine in mice.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Clonidine; Injections, Intraperitoneal; Lithium; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; Yohimbine | 2002 |
Prior iontophoresis of saline enhances vasoconstriction to phenylephrine and clonidine in the skin of the human forearm.
Topics: Administration, Cutaneous; Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Female; Forearm; Humans; Iontophoresis; Male; Phenylephrine; Prazosin; Skin; Sodium Chloride; Vasoconstriction; Yohimbine | 2002 |
Noradrenaline-induced contraction of human saphenous vein and human internal mammary artery: involvement of different alpha-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Aged; Clonidine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Regression Analysis; Saphenous Vein; Yohimbine | 2002 |
Noradrenaline release in rat locus coeruleus is regulated by both opioid and alpha(2) -adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Substance Withdrawal Syndrome; Yohimbine | 2002 |
The role of alpha2-adrenoceptors in the modulatory effects of morphine on seizure susceptibility in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Differential Threshold; Disease Susceptibility; Male; Mice; Mice, Inbred Strains; Morphine; Narcotics; Receptors, Adrenergic, alpha; Seizures; Stress, Physiological; Yohimbine | 2002 |
Adrenoceptors of the medial septal area modulate water intake and renal excretory function induced by central administration of angiotensin II.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Clonidine; Drinking; Injections, Intraventricular; Kidney; Male; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Septum of Brain; Sodium; Urine; Yohimbine | 2002 |
alpha2-Adrenoceptors control the release of noradrenaline but not neuropeptide Y from perivascular nerve terminals.
Topics: Acetylcholinesterase; Animals; Clonidine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Immunohistochemistry; Microscopy, Fluorescence; Neurons; Neuropeptide Y; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reperfusion; Reserpine; Time Factors; Tissue Distribution; Yohimbine | 2002 |
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergism; Drug Therapy, Combination; Meloxicam; Mice; Naproxen; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles; Yohimbine | 2002 |
Spinal alpha(2)-adrenoceptors are involved in the MACbar-sparing effect of systemic clonidine in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Clonidine; Hemodynamics; Injections, Spinal; Male; Methyl Ethers; Phentolamine; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sevoflurane; Spinal Cord; Yohimbine | 2002 |
The role of alpha-adrenoceptors in the amnestic effect of intracerebroventricular dexamethasone.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amnesia; Animals; Avoidance Learning; Clonidine; Dexamethasone; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Memory; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 2002 |
Sepsis causes presynaptic histamine H3 and alpha2-adrenergic dysfunction in canine myocardium.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Culture Techniques; Dogs; GTP-Binding Proteins; Heart; Histamine; Myocardial Contraction; Pertussis Toxin; Receptors, Adrenergic, alpha-2; Receptors, Histamine H3; Shock, Septic; Sympathetic Nervous System; Yohimbine | 2002 |
Rhythmic properties of neurons in the rostral ventrolateral medulla of the rat in vitro: effects of clonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Electrophysiology; Male; Medulla Oblongata; Membrane Potentials; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley; Yohimbine | 2002 |
Gastrointestinal transit in mice treated with various extracts of date (Phoenix dactylifera L.).
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arecaceae; Charcoal; Clonidine; Dose-Response Relationship, Drug; Fruit; Gastrointestinal Transit; Male; Mice; Plant Extracts; Yohimbine | 2003 |
Mediation of contraction in rat cauda epididymidis by alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epididymis; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 2002 |
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Azepines; Brimonidine Tartrate; Clonidine; Idazoxan; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxazoles; Prostaglandins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Yohimbine | 2002 |
Morphine state-dependent learning: interactions with alpha2-adrenoceptors and acute stress.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Male; Memory; Mice; Morphine; Narcotics; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Restraint, Physical; Stress, Physiological; Time Factors; Yohimbine | 2003 |
An antihypokinesic action of alpha2-adrenoceptors upon MPTP-induced behaviour deficits in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clonidine; Dopamine; Dopamine Agonists; Drug Interactions; Drug Therapy, Combination; Guanfacine; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Parkinsonian Disorders; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Yohimbine | 2003 |
Yohimbine reverses the exhaustion of the coital reflex in spinal male rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Copulation; Ejaculation; Electromyography; Evoked Potentials; Male; Physical Stimulation; Prazosin; Rats; Rats, Wistar; Reaction Time; Spinal Cord; Spinal Cord Injuries; Yohimbine | 2003 |
Adrenoceptor mechanisms underlying imipramine-induced memory deficits in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Electroshock; Hippocampus; Imipramine; Male; Memory; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
The contribution of alpha2-adrenoceptor and opioid receptor mechanisms to antinociception differs in Lewis and Fischer 344 rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Morphine; Naloxone; Pain Threshold; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Species Specificity; Time Factors; Yohimbine | 2003 |
Alpha2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Clonidine; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Heterotrimeric GTP-Binding Proteins; Imines; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Potentials; Mice; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxins; Patch-Clamp Techniques; Pertussis Toxin; Piperazines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyridines; Receptors, Adrenergic, alpha-2; Serotonin Antagonists; Sulfonamides; Yohimbine | 2003 |
Dual effect of agmatine in the bisected rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Yohimbine | 2003 |
Alpha-2-adrenoceptor hyporesponsiveness in isolated tissues of cholestatic animals: involvement of opioid and nitric oxide systems.
Topics: Animals; Catecholamines; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Mice; Naltrexone; Nitric Oxide; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 2003 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
Alpha-2 adrenoceptor mediating the facilitatory effect of norepinephrine on the glycine response in the spinal dorsal horn neuron of the rat.
Topics: Alkaloids; Animals; Benzophenanthridines; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Electric Conductivity; Enzyme Inhibitors; Glycine; Isoquinolines; Neurons; Norepinephrine; Nystatin; Patch-Clamp Techniques; Phenanthridines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sulfonamides; Yohimbine | 2003 |
Effects of castration and of testosterone replacement on alpha(1)-adrenoceptor subtypes in the rat vas deferens.
Topics: Animals; Castration; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Neuronal Plasticity; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Testosterone; Time Factors; Vas Deferens; Yohimbine | 2003 |
Role of I1-imidazoline receptors within the caudal ventrolateral medulla in cardiovascular responses to clonidine in rats.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Idazoxan; Imidazoline Receptors; Injections, Intravenous; Male; Medulla Oblongata; Microelectrodes; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine | 2003 |
Effects of imipramine on the expression and development of morphine dependence in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors.
Topics: Adipose Tissue, Brown; Amiloride; Animals; Binding Sites; Binding, Competitive; Cell Line, Tumor; Clonidine; Culture Techniques; Dose-Response Relationship, Drug; Guanabenz; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Liver; Mammary Neoplasms, Animal; Mice; Protein Binding; Rats; Receptors, Drug; Species Specificity; Yohimbine | 2003 |
Effect of clonidine on colonic motility in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Colon; Drug Interactions; Gastrointestinal Motility; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Time Factors; Yohimbine | 2003 |
Clonidine-induced coronary vasodilatation in isolated guinea pig heart is not mediated by endothelial alpha2 adrenoceptors.
Topics: Animals; Clonidine; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Guinea Pigs; Heart; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phentolamine; Prazosin; Ranitidine; Receptors, Adrenergic, alpha-2; Receptors, Histamine H2; Vasoconstriction; Vasodilation; Yohimbine | 2003 |
Pharmacological blockade of alpha2-adrenoceptors induces reinstatement of cocaine-seeking behavior in squirrel monkeys.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine-Related Disorders; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Extinction, Psychological; Flupenthixol; Hydrocortisone; Motor Activity; Saimiri; Self Administration; Serine Endopeptidases; Time Factors; Vocalization, Animal; Yohimbine | 2004 |
Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Function; Atrial Natriuretic Factor; Benzofurans; Blood Pressure; Cardiomegaly; Clonidine; Heart Atria; Hemodynamics; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine | 2004 |
Clonidine improves spontaneous baroreflex sensitivity in conscious mice through parasympathetic activation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Baroreflex; Blood Pressure; Clonidine; Consciousness; Heart Rate; Male; Metoprolol; Mice; Monitoring, Physiologic; Parasympathetic Nervous System; Respiration; Species Specificity; Sympathetic Nervous System; Telemetry; Yohimbine | 2004 |
The effects of the alpha2-adrenergic receptor agonists clonidine and rilmenidine, and antagonists yohimbine and efaroxan, on the spinal cholinergic receptor system in the rat.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Benzofurans; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Injections, Spinal; Ligands; Male; Microdialysis; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Cholinergic; Rilmenidine; Spinal Cord; Time Factors; Yohimbine | 2004 |
alpha2-Adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Clonidine; GTP-Binding Proteins; Neocortex; Norepinephrine; Patch-Clamp Techniques; Pertussis Toxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2004 |
Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiloride; Animals; Biological Transport; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Norepinephrine; Octopamine; Ouabain; Phenylephrine; Prazosin; Propranolol; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Up-Regulation; Water-Electrolyte Balance; Yohimbine | 2004 |
Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Avoidance Learning; Brain; Clonidine; Dose-Response Relationship, Drug; Electroshock; Fear; Guanabenz; Imidazoles; Indoles; Injections, Intraperitoneal; Isoindoles; Male; Mental Recall; Mice; Motor Activity; Motor Skills; Reaction Time; Receptors, Adrenergic, alpha-2; Yohimbine | 2004 |
Adrenergic involvement in the locus ceruleus and adjoining regions in the facilitation of predatory attack behavior as induced by hypothalamic stimulation in cats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Electric Stimulation; Electrodes, Implanted; Female; Hypothalamus; Locus Coeruleus; Male; Microinjections; Norepinephrine; Predatory Behavior; Sympathetic Nervous System; Yohimbine | 2004 |
Alpha2-adrenoceptor modulation of long-term potentiation elicited in vivo in rat occipital cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Long-Term Potentiation; Male; Occipital Lobe; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2004 |
Noradrenergic inputs mediate state dependence of auditory responses in the avian song system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Arousal; Auditory Perception; Clonidine; Dose-Response Relationship, Drug; Finches; Guanabenz; Idazoxan; Imidazoles; Isoproterenol; Male; Norepinephrine; Oxathiins; Phenylephrine; Propanolamines; Prosencephalon; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Vocalization, Animal; Yohimbine | 2004 |
Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Brain; Clonidine; DNA; Down-Regulation; Drug Interactions; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Up-Regulation; Yohimbine | 2004 |
Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Bicuculline; Brain Stem; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Synapses; Synaptophysin; Time Factors; Yohimbine | 2005 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Autoreceptors; Clonidine; Desipramine; Dose-Response Relationship, Drug; Extracellular Fluid; Male; Microdialysis; Norepinephrine; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time; Yohimbine | 2004 |
Locus coeruleus activity in perinatally protein-deprived rats: effects of fluoxetine administration.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Antidepressive Agents, Second-Generation; Biogenic Monoamines; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Extracellular Space; Female; Fluoxetine; Locus Coeruleus; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Pregnancy; Protein-Energy Malnutrition; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Yohimbine | 2004 |
Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blotting, Western; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Norepinephrine; Physical Conditioning, Animal; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Yohimbine | 2004 |
Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alcoholism; Animals; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reinforcement, Psychology; Self Administration; Stress, Psychological; Yohimbine | 2005 |
The effect of alpha2-adrenergic receptors on cutaneous water evaporation in the rock pigeon (Columba livia).
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Columbidae; Desiccation; Isoproterenol; Receptors, Adrenergic, alpha-2; Skin; Temperature; Water; Yohimbine | 2004 |
Mid-lumbar segments are needed for the expression of locomotion in chronic spinal cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Deceleration; Electric Stimulation; Electrodes, Implanted; Electromyography; Exercise Test; Functional Laterality; Hindlimb; Injections, Spinal; Locomotion; Lumbosacral Region; Spinal Cord Injuries; Time Factors; Yohimbine | 2005 |
Role of alpha and beta adrenoceptors in locus coeruleus stimulation-induced reduction in rapid eye movement sleep in freely moving rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Clonidine; Electric Stimulation; Electroencephalography; Electromyography; Electrooculography; Locus Coeruleus; Male; Models, Biological; Picrotoxin; Prazosin; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep, REM; Time Factors; Wakefulness; Yohimbine | 2005 |
Urinary responses to acute moxonidine are inhibited by natriuretic peptide receptor antagonist.
Topics: Animals; Antihypertensive Agents; Benzofurans; Clonidine; Cyclic GMP; Diuresis; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Natriuresis; Natriuretic Peptides; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2005 |
Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanfacine; Imidazoles; Injections; Male; Medetomidine; Neural Inhibition; Piperazines; Prazosin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Reflex, Startle; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Yohimbine | 2005 |
Transregulation of the alpha2-adrenergic signal transduction pathway by chronic beta-blockade: a novel mechanism for decreased platelet aggregation in patients.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Platelets; Cell Membrane; Clonidine; Electrophoresis, Polyacrylamide Gel; Epinephrine; GTP-Binding Proteins; Humans; Immunoblotting; In Vitro Techniques; Platelet Aggregation; Receptors, Adrenergic, alpha-2; Signal Transduction; Yohimbine | 2005 |
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine | 2005 |
Effects of alpha- and beta-adrenergic agonists on Toxoplasma gondii infection in murine macrophages.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Cells, Cultured; Clonidine; Humans; Isoproterenol; Macrophages; Mice; Phentolamine; Phenylephrine; Receptors, Adrenergic, alpha-2; Toxoplasma; Yohimbine | 2005 |
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Northern; Brimonidine Tartrate; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; Gene Expression Regulation; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine | 2005 |
alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bilirubin; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Male; Mesenteric Arteries; Mesentery; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilation; Vasodilator Agents; Yohimbine | 2005 |
Ultrasonic vocalization production of preweanling rats: effects of central and peripheral administration of alpha2-adrenoceptor agonists.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Rats; Rats, Sprague-Dawley; Ultrasonics; Vocalization, Animal; Yohimbine | 2005 |
Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzoxazoles; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Intracellular Signaling Peptides and Proteins; Locus Coeruleus; Male; Naphthyridines; Neural Pathways; Neurons; Neuropeptides; Norepinephrine; Orexin Receptors; Orexins; Organ Culture Techniques; Potassium; Rats; Receptors, Adrenergic, alpha-2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Urea; Wakefulness; Yohimbine | 2005 |
Alpha-adrenergic modulation of synaptic transmission in rabbit pancreatic ganglia.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Ganglia, Autonomic; Guanethidine; Male; Neural Inhibition; Norepinephrine; Pancreas; Phenylephrine; Rabbits; Receptors, Adrenergic; Synaptic Transmission; Yohimbine | 2005 |
A pharmacological modulation of opiate withdrawal using an up-/down-regulation of the noradrenergic system in opiate-dependent rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Male; Morphine; Morphine Dependence; Narcotics; Norepinephrine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Up-Regulation; Yohimbine | 2006 |
Long-lasting effects of yohimbine on the ejaculatory function in male dogs.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Ejaculation; Idazoxan; Male; Penile Erection; Sexual Behavior, Animal; Time Factors; Yohimbine | 2005 |
Characterisation of alpha2-adrenoceptor subtypes involved in gastric emptying, gastric motility and gastric mucosal defence.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Yohimbine | 2005 |
The HND mouse, a nonobese model of type 2 diabetes mellitus with impaired insulin secretion.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Animals, Wild; Blood Glucose; Clonidine; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Epinephrine; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Yohimbine | 2005 |
alpha2-Adrenoceptor-mediated modulation of the release of GABA and noradrenaline in the rat substantia nigra pars reticulata.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Norepinephrine; Organ Culture Techniques; Rats; Receptors, Adrenergic, alpha-2; Substantia Nigra; Yohimbine | 2006 |
Noradrenergic modulation of activity in a vocal control nucleus in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Evoked Potentials; Finches; In Vitro Techniques; Male; Motor Neurons; Norepinephrine; Patch-Clamp Techniques; Psychomotor Performance; Receptors, Adrenergic, alpha-2; Signal Transduction; Vocalization, Animal; Yohimbine | 2006 |
Acute lead exposure and contraction of rat isolated aorta induced by D1-dopaminergic and alpha-adrenergic drugs.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Aorta; Benzazepines; Cardiotonic Agents; Clonidine; Dopamine; Dose-Response Relationship, Drug; Lead; Male; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Wistar; Yohimbine | 2006 |
Alpha1L-adrenoceptors mediate contractions of the isolated mouse prostate.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Dopamine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Indoles; Isoproterenol; Male; Mice; Muscle Contraction; Norepinephrine; Phenylephrine; Prazosin; Prostate; Receptors, Adrenergic, alpha-1; Yohimbine | 2006 |
Alpha-2 adrenergic regulation of pedunculopontine nucleus neurons during development.
Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Biotin; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; NADP; Neurons; Pedunculopontine Tegmental Nucleus; Pregnancy; Pyrimidines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Yohimbine | 2006 |
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Clonidine inhibits the canine external carotid vasodilatation to capsaicin by alpha2A/2C-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Artery, External; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Indoles; Isoindoles; Male; Phenylephrine; Quinolizines; Receptors, Adrenergic, alpha-2; Reproducibility of Results; Vasodilation; Yohimbine | 2006 |
The contribution of alpha-1 and alpha-2 adrenoceptors in peripheral imidazoline and adrenoceptor agonist-induced nociception.
Topics: Adrenergic alpha-Agonists; Agmatine; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoline Receptors; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Brimonidine Tartrate; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methoxamine; Nitric Oxide; Phenylephrine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin; Vasoconstrictor Agents; Vasodilation; Yohimbine | 2006 |
Clonidine in horses: identification, detection, and clinical pharmacology.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Doping in Sports; Female; Gas Chromatography-Mass Spectrometry; Horses; Physical Conditioning, Animal; Sensitivity and Specificity; Substance Abuse Detection; Yohimbine | 2006 |
Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cocaine; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2006 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Effects of alpha2-adrenoceptor agonists on tetrodotoxin-resistant Na+ channels in rat dorsal root ganglion neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Resistance; Ganglia, Spinal; Lidocaine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Yohimbine | 2007 |
Alpha-2 agonists decrease expression of morphine-induced conditioned place preference.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Clonidine; Conditioning, Operant; Male; Mice; Morphine; Receptors, Adrenergic, alpha-2; Reward; Xylazine; Yohimbine | 2008 |
Stimulation of alpha2-adrenoceptors suppresses excitatory synaptic transmission in the medial prefrontal cortex of rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bacterial Proteins; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Guanfacine; In Vitro Techniques; Neural Inhibition; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Repressor Proteins; Suramin; Yohimbine | 2008 |
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Terbutaline; Vas Deferens; Vasodilation; Xylazine; Yohimbine | 2008 |
Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 Cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzophenanthridines; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Immunoblotting; Microtubule-Associated Proteins; Microtubules; Models, Biological; Neurites; Nocodazole; PC12 Cells; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-2; Serine; Yohimbine | 2008 |
Pharmacological profile of the clonidine-induced inhibition of vasodepressor sensory outflow in pithed rats: correlation with alpha(2A/2C)-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Blood Vessels; Calcitonin Gene-Related Peptide; Clonidine; Decerebrate State; Electric Stimulation; Heart Rate; Imidazoles; In Vitro Techniques; Isoindoles; Male; Neurons, Afferent; Quinolizines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Effects of spinal alpha(2)-adrenoceptor and I(1)-imidazoline receptor activation on hindlimb movement induction in spinal cord-injured mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Clonidine; Hindlimb; Imidazoles; Imidazoline Receptors; Male; Mice; Mice, Inbred Strains; Movement; Receptors, Adrenergic, alpha-2; Spinal Cord; Spinal Cord Injuries; Yohimbine | 2008 |
Sex-specific modulation of spinal nociception by alpha2-adrenoceptors: differential regulation by estrogen and testosterone.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Castration; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Estrogens; Female; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sex Characteristics; Testosterone; Time Factors; Yohimbine | 2008 |
Noradrenaline modulates neuronal responses to GABA in vestibular nuclei.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Neural Inhibition; Neurons; Norepinephrine; Rats; Rats, Wistar; Timolol; Vestibular Nuclei; Yohimbine | 2008 |
alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Burns; Clonidine; Female; Hot Temperature; Humans; Hyperalgesia; Iontophoresis; Male; Nociceptors; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Sensory Receptor Cells; Skin; Yohimbine; Young Adult | 2009 |
Potentiation by yohimbine of alpha-adrenoceptor-mediated vasoconstriction in response to clonidine in the rabbit ear vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Ear; Imidazoles; Male; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Vasoconstrictor Agents; Veins; Yohimbine | 2008 |
Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzazepines; Benzofurans; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraperitoneal; Ligands; Male; Mice; Muscle Rigidity; Muscle, Skeletal; Parkinsonian Disorders; Reserpine; Time Factors; Yohimbine | 2008 |
Alpha2-adrenoceptor action on cell proliferation and mammary tumour growth in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line, Tumor; Cell Proliferation; Clonidine; Dexmedetomidine; Drug Inverse Agonism; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Contrasting effects of presynaptic alpha2-adrenergic autoinhibition and pharmacologic augmentation of presynaptic inhibition on sympathetic heart rate control.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Computer Simulation; Dose-Response Relationship, Drug; Electric Stimulation; Feedback, Physiological; Heart; Heart Rate; Models, Cardiovascular; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Sympathetic Nervous System; Time Factors; Yohimbine | 2008 |
Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Clonidine; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Extinction, Psychological; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Receptors, Corticotropin-Releasing Hormone; Self Administration; Yohimbine | 2009 |
The effect of clonidine on VEGF expression in human retinal pigment epithelial cells (ARPE-19).
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Cell Line; Clonidine; Enzyme Inhibitors; Gene Expression; Humans; Imidazoline Receptors; Interleukin-1beta; MAP Kinase Kinase 1; MAP Kinase Kinase 2; p38 Mitogen-Activated Protein Kinases; Receptors, Adrenergic, alpha-2; Retinal Pigment Epithelium; RNA, Messenger; Vascular Endothelial Growth Factor A; Yohimbine | 2009 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
The role of noradrenaline and 5-hydroxytryptamine in yohimbine-induced increases in alcohol-seeking in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alcohol Drinking; Animals; Biogenic Monoamines; Brain Chemistry; Clonidine; Dose-Response Relationship, Drug; Isoquinolines; Male; Naphthyridines; Norepinephrine; Oxidopamine; Piperazines; Pyridines; Rats; Recurrence; Self Administration; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Sympathectomy, Chemical; Sympatholytics; Yohimbine | 2009 |
Role of adrenergic alpha-2-receptors on feeding behavior in layer-type chicks.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; beta-Endorphin; Chickens; Clonidine; Eating; Feeding Behavior; Male; Neuropeptide Y; Neurotransmitter Agents; Receptors, Adrenergic, alpha-2; Yohimbine | 2009 |
Complex cardiovascular actions of alpha-adrenergic receptors expressed in the nucleus tractus solitarii of rats.
Topics: Animals; Blood Pressure; Chemoreceptor Cells; Clonidine; Gene Expression Profiling; Heart Rate; Phentolamine; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Solitary Nucleus; Yohimbine | 2009 |
Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Calcitonin Gene-Related Peptide; Cells, Cultured; Clonidine; Endothelial Cells; Gene Expression; Gene Expression Regulation; Humans; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Yohimbine | 2009 |
Metaplasticity of hypothalamic synapses following in vivo challenge.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Biophysics; Carbolines; Clonidine; Down-Regulation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; Guanosine Diphosphate; Hypothalamus; In Vitro Techniques; Intracranial Hemorrhages; Long-Term Synaptic Depression; Male; Microinjections; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Synapses; Thionucleotides; Yohimbine | 2009 |
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Catheterization; Clonidine; Colon; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Rectum; Yohimbine | 2009 |
Noradrenergic modulation of neuronal responses to glutamate in the vestibular complex.
Topics: Action Potentials; Adrenergic Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Glutamic Acid; Neurons; Norepinephrine; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission; Timolol; Vestibular Nuclei; Yohimbine | 2009 |
Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models.
Topics: Animals; Atropine; Clonidine; Constipation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Indoles; Loperamide; Male; Mice; Mice, Inbred Strains; Mustard Plant; Naloxone; Plant Oils; Transient Receptor Potential Channels; TRPA1 Cation Channel; Yohimbine | 2009 |
Testosterone is essential for alpha(2)-adrenoceptor-induced antinociception in the trigeminal region of the male rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catheterization; Clonidine; Estradiol; Estrogens; Hormone Replacement Therapy; Hot Temperature; Male; N-Methylaspartate; Orchiectomy; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Testosterone; Testosterone Propionate; Time Factors; Trigeminal Nuclei; Yohimbine | 2009 |
Pharmacological characterization of a Bombyx mori alpha-adrenergic-like octopamine receptor stably expressed in a mammalian cell line.
Topics: Amidines; Animals; Bombyx; Calcium; Cell Line; Chlorpromazine; Clonidine; Cyclic AMP; Imidazolidines; Insect Proteins; Insecticides; Mammals; Naphazoline; Receptors, Adrenergic, alpha; Receptors, Biogenic Amine; Tolazoline; Yohimbine | 2010 |
Effects of acute exposure of alpha 1- and alpha 2-adrenoreceptor agonist or antagonist on capsaicin-evoked substance P release from dorsal root ganglion neurons in vitro.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Capsaicin; Cells, Cultured; Clonidine; Ganglia, Spinal; Neurons; Phenylephrine; Prazosin; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Yohimbine | 2010 |
α2-adrenergic drugs modulate the binding of [18F]fallypride to dopamine D2/3 receptors in striatum of living mouse.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzamides; Binding, Competitive; Brain Mapping; Clonidine; Corpus Striatum; Dopamine; Female; Idazoxan; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Pyrrolidines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Yohimbine | 2010 |
alpha(1)- and alpha(2)-Adrenoceptor hyporesponsiveness in isolated bisected vas deferens of bile duct-ligated rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Clonidine; Electric Stimulation; In Vitro Techniques; Ligation; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine | 2010 |
Antinociceptive synergism of MD-354 and clonidine. Part II. The alpha-adrenoceptor component.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Clonidine; Drug Synergism; Guanidines; Imidazoles; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Receptors, Adrenergic, alpha; Tail; Yohimbine | 2010 |
Effects of selective alpha 2-adrenoreceptor stimulation on capsaicin-evoked substance P release from primary cultured dorsal root ganglion neurons.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Capsaicin; Cells, Cultured; Clonidine; Ganglia, Spinal; Neurons; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; TRPV Cation Channels; Yohimbine | 2010 |
Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors.
Topics: Agmatine; Animals; Arginine; Biguanides; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Enzyme Inhibitors; Guanidines; Idazoxan; Male; Mice; Motor Activity; Nicotine; Receptors, Adrenergic, alpha-2; Yohimbine | 2010 |
Noradrenergic modulation of seizure activity.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Deep Brain Stimulation; Electrodes, Implanted; Electroencephalography; Hippocampus; Humans; Injections, Intraventricular; Locus Coeruleus; Male; Microinjections; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine | 2010 |
The role of opioid system and its interaction with sympathetic nervous system in the processing of polycystic ovary syndrome modeling in rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Disease Models, Animal; Estradiol; Female; Gonadal Steroid Hormones; Naltrexone; Narcotic Antagonists; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Opioid; Sympathetic Nervous System; Yohimbine | 2011 |
Modulation of natural killer cell function by alpha-adrenoreceptor-coupled signalling.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Cytotoxicity Tests, Immunologic; Estrenes; Flow Cytometry; Intracellular Signaling Peptides and Proteins; Isoquinolines; Killer Cells, Natural; Phenylephrine; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spleen; Sulfonamides; Type C Phospholipases; Yohimbine | 2010 |
Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Head Movements; Male; Movement Disorders; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2011 |
Tonic inhibition of allergic itch signaling by the descending noradrenergic system in mice.
Topics: Animals; Bites and Stings; Clonidine; Culicidae; Histamine Antagonists; Hypersensitivity; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Norepinephrine; Pruritus; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2011 |
Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Brain; Brain Ischemia; Clonidine; Corticosterone; Hypothalamo-Hypophyseal System; Male; Maze Learning; Memory; Neurons; Norepinephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Time Factors; Yohimbine | 2011 |
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine | 2011 |
Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Arcuate Nucleus of Hypothalamus; Arginine; Clonidine; Drug Synergism; Eating; Feeding Behavior; Hyperphagia; Male; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Yohimbine | 2011 |
α(2)-Adrenoceptors enhance cell proliferation and mammary tumor growth acting through both the stroma and the tumor cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Breast Neoplasms; Catecholamines; Cell Line; Cell Line, Tumor; Cell Proliferation; Clonidine; Disease Progression; Epithelial Cells; Female; Fibroblasts; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Receptors, Adrenergic, alpha-2; Stromal Cells; Yohimbine | 2011 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
[Effects of estrogen and keishibukuryogan on hot flash-like symptoms induced by yohimbine in ovariectomized rats].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Body Temperature; Clonidine; Disease Models, Animal; Drugs, Chinese Herbal; Estradiol; Estrogens; Female; Hot Flashes; Humans; Menopause; Norepinephrine; Ovariectomy; Phytotherapy; Rats; Rats, Sprague-Dawley; Rectum; Skin Temperature; Tail; Yohimbine | 2011 |
Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Animals; Astrocytes; Atomoxetine Hydrochloride; Cells, Cultured; Chemokine CCL2; Clonidine; Cyclic AMP; Desipramine; Isoproterenol; Norepinephrine; Propylamines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2011 |
Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analysis of Variance; Animals; Clonidine; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Inflammation; Macrophage-1 Antigen; Male; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sciatica; Time Factors; Yohimbine | 2011 |
Modulation of WIN55,212-2 state-dependent memory by α2-adrenergic receptors of the dorsal hippocampus.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzoxazines; CA1 Region, Hippocampal; Cannabinoid Receptor Antagonists; Clonidine; Male; Memory; Morpholines; Naphthalenes; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Statistics, Nonparametric; Yohimbine | 2011 |
The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Adrenocorticotropic Hormone; alpha-Methyltyrosine; Analysis of Variance; Animals; Antihypertensive Agents; Clonidine; Corticosterone; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Female; Hypnotics and Sedatives; Rats; Rats, Wistar; Reserpine; Yohimbine | 2012 |
Dysfunction of neurotransmitter modulation system on adrenergic nerves of caudal artery in type 2 diabetic Goto-Kakizaki rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Animals; Arteries; Clonidine; Diabetes Mellitus, Type 2; Electric Stimulation; In Vitro Techniques; Norepinephrine; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Sympathetic Nervous System; Yohimbine | 2012 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine | 2013 |
Corticotropin-releasing factor (CRF) and α 2 adrenergic receptors mediate heroin withdrawal-potentiated startle in rats.
Topics: Acoustic Stimulation; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Clonidine; Conditioning, Operant; Corticotropin-Releasing Hormone; Disease Models, Animal; Heroin; Male; Narcotics; Norepinephrine; Psychoacoustics; Pyrimidines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex, Startle; Self Administration; Substance Withdrawal Syndrome; Time Factors; Yohimbine | 2013 |
Modulation of muscimol state-dependent memory by α2-adrenoceptors of the dorsal hippocampal area.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Avoidance Learning; CA1 Region, Hippocampal; Clonidine; GABA-A Receptor Agonists; Male; Memory Disorders; Mice; Muscimol; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
The role of α₂-adrenoceptors in the anti-convulsant effects of cannabinoids on pentylenetetrazole-induced seizure threshold in mice.
Topics: Animals; Anticonvulsants; Arachidonic Acids; Cannabinoids; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine | 2013 |
Noradrenergic alpha-2 receptor modulators in the ventral bed nucleus of the stria terminalis: effects on anxiety behavior in postpartum and virgin female rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anxiety; Clonidine; Female; Postpartum Period; Rats; Rats, Long-Evans; Septal Nuclei; Yohimbine | 2013 |
The role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex on allodynia following spared nerve injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Bicuculline; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Male; Norepinephrine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sciatic Neuropathy; Yohimbine | 2013 |
Clonidine suppresses the induction of long-term potentiation by inhibiting HCN channels at the Schaffer collateral-CA1 synapse in anesthetized adult rats.
Topics: Aging; Anesthesia; Animals; Blood Pressure; CA1 Region, Hippocampal; Cells, Cultured; Clonidine; Glutamates; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Injections, Intraperitoneal; Injections, Intraventricular; Long-Term Potentiation; Male; Neurons; Pyrimidines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Yohimbine | 2013 |
Noradrenaline and neuropeptide Y contribute to initial, but not sustained, vasodilatation in response to local skin warming in humans.
Topics: Adult; Arginine; Clonidine; Humans; Male; Neuropeptide Y; Nitric Oxide Synthase Type III; Nitroprusside; Norepinephrine; Propranolol; Skin; Skin Temperature; Vasodilation; Yohimbine | 2014 |
Hippocampal α-adrenoceptors involve in the effect of histamine on spatial learning.
Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; CA1 Region, Hippocampal; Clonidine; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Male; Maze Learning; Phenylephrine; Prazosin; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Task Performance and Analysis; Yohimbine | 2014 |
Activation of spinal α2 adrenergic receptors induces hyperglycemia in mouse though activating sympathetic outflow.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Blood Glucose; Clonidine; Hyperglycemia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2014 |
The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anticonvulsants; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Pentylenetetrazole; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Seizures; Theophylline; Yohimbine | 2014 |
Hypertensive urgency: an important aetiology of rebound hypertension.
Topics: Adrenergic alpha-2 Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Emergencies; Herb-Drug Interactions; Humans; Hypertension; Labetalol; Male; Middle Aged; Yohimbine | 2014 |
Intrathecal administration of clonidine or yohimbine decreases the nociceptive behavior caused by formalin injection in the marsh terrapin (Pelomedusa subrufa).
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Injections, Spinal; Methysergide; Pain; Pain Measurement; Random Allocation; Serotonin Antagonists; Turtles; Yohimbine | 2014 |
PTSD-like memory generated through enhanced noradrenergic activity is mitigated by a dual step pharmacological intervention targeting its reconsolidation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Blood Pressure; Cannabidiol; Clonidine; Cycloserine; Excitatory Amino Acid Agents; Extinction, Psychological; Fear; Male; Memory; Psychotropic Drugs; Random Allocation; Rats, Wistar; Stress Disorders, Post-Traumatic; Yohimbine | 2014 |
Noradrenergic modulation of risk/reward decision making.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Animal; Choice Behavior; Clonidine; Conditioning, Operant; Decision Making; Guanfacine; Male; Probability; Rats; Rats, Long-Evans; Reward; Risk; Risk-Taking; Yohimbine | 2015 |
Protective effects of lithium chloride on seizure susceptibility: Involvement of α2-adrenoceptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Benzofurans; Brimonidine Tartrate; Clonidine; Drug Interactions; Imidazoles; Lithium Chloride; Male; Mice; Pentylenetetrazole; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine | 2015 |
Influence of morphine on medial prefrontal cortex alpha2 adrenergic system in passive avoidance learning in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amnesia; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Male; Microinjections; Morphine; Prefrontal Cortex; Rats; Receptors, Adrenergic, alpha-2; Yohimbine | 2015 |
Norepinephrine responses in rat renal and femoral veins are reinforced by vasoconstrictor prostanoids.
Topics: Animals; Clonidine; Endothelium, Vascular; Femoral Vein; Kidney; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2015 |
Modulation of cannabinoid signaling by amygdala α2-adrenergic system in fear conditioning.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; Arachidonic Acids; Auditory Perception; Basolateral Nuclear Complex; Cannabinoid Receptor Agonists; Clonidine; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Male; Memory; Mice; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-2; Yohimbine | 2016 |
Modulatory effects of the basolateral amygdala α2-adrenoceptors on nicotine-induced anxiogenic-like behaviours of rats in the elevated plus maze.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anxiety; Basolateral Nuclear Complex; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Maze Learning; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2016 |
The effect of CA1 α2 adrenergic receptors on memory retention deficit induced by total sleep deprivation and the reversal of circadian rhythm in a rat model.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Animal; CA1 Region, Hippocampal; Circadian Rhythm; Clonidine; Disease Models, Animal; Memory Consolidation; Memory Disorders; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Retention, Psychology; Sleep Deprivation; Yohimbine | 2016 |
Involvement of medial prefrontal cortex alpha-2 adrenoceptors on memory acquisition deficit induced by arachidonylcyclopropylamide, a cannabinoid CB1 receptor agonist, in rats; possible involvement of Ca2+ channels.
Topics: Amnesia; Animals; Arachidonic Acids; Calcium Channels; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Male; Memory; Memory Disorders; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-2; Yohimbine | 2016 |
Interactions between β-adrenergic vasodilation and cervical sympathetic nerves are mediated by α
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Electric Stimulation; Lip; Male; Masseter Muscle; Mydriatics; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasodilation; Vasodilator Agents; Yohimbine | 2017 |
Modulation of formalin-induced pain-related behaviour by clonidine and yohimbine in the Speke's hinged tortoise (Kiniskys spekii).
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Pain; Turtles; Yohimbine | 2017 |
Novel technique to determine the pK
Topics: Animals; Clonidine; Cystamine; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Mesenteric Arteries; Mice; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 2017 |
α
Topics: Adrenergic Agents; Adrenergic Neurons; Analysis of Variance; Animals; Cell Count; Clonidine; Dose-Response Relationship, Drug; Drug Administration Routes; Hippocampus; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2018 |
[ADRENERGIC AND IMIDAZOLINE MECHANISMS OF CIRCULATION CENTRAL REGULATION IN RATS OF DIFFERENT LINES].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Baroreflex; Benzofurans; Blood Pressure; Brain; Clonidine; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System; Yohimbine | 2016 |
Impact of stress response systems on forced choice recognition in an experimental trauma film paradigm.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Clonidine; Female; Follow-Up Studies; Humans; Hydrocortisone; Mental Recall; Motion Pictures; Norepinephrine; Psychological Trauma; Recognition, Psychology; Stress, Psychological; Yohimbine; Young Adult | 2018 |
Alpha
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Axial Length, Eye; Brimonidine Tartrate; Chickens; Clonidine; Disease Models, Animal; Guanfacine; Intravitreal Injections; Male; Myopia; Sensory Deprivation; Yohimbine | 2019 |
Bidirectional pharmacological perturbations of the noradrenergic system differentially affect tactile detection.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Animals; Clonidine; Female; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Touch; Yohimbine | 2020 |
Noradrenergic Components of Locomotor Recovery Induced by Intraspinal Grafting of the Embryonic Brainstem in Adult Paraplegic Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brain Stem; Brain Tissue Transplantation; Clonidine; Female; Hindlimb; Locomotion; Nerve Regeneration; Neurons; Paraplegia; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Yohimbine | 2020 |
Taking advantage of fear generalization-associated destabilization to attenuate the underlying memory via reconsolidation intervention.
Topics: Adrenergic alpha-Agonists; Animals; CA1 Region, Hippocampal; Clonidine; Early Growth Response Protein 1; Extinction, Psychological; Fear; Generalization, Psychological; Male; Memory; Memory Consolidation; Memory Disorders; Mental Recall; Rats; Rats, Wistar; Sympatholytics; Yohimbine | 2020 |
The effects of clonidine and yohimbine in the tail flick and hot plate tests in the naked mole rat (Heterocephalus glaber).
Topics: Analgesics; Animals; Clonidine; Mole Rats; Yohimbine | 2021 |
Clonidine ameliorates cerebral ischemia-reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor.
Topics: Animals; Brain Ischemia; Clonidine; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Yohimbine | 2022 |
Intracranial hemorrhage after a single dose of Yohimbine in a chronic user of clonidine.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Intracranial Hemorrhages; Sympathomimetics; Yohimbine | 2022 |