clonidine and selegiline

clonidine has been researched along with selegiline in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's2 (10.53)18.2507
2000's10 (52.63)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E1
Egashira, T; Obata, T; Yamanaka, Y1
Blier, P; de Montigny, C1
Bailey, BA; Boulton, AA; Greenshaw, AJ; Kwok, RP; O'Regan, D; Yu, PH1
Riddle, MA; Scahill, LD; Walkup, JT1
Cavalletti, M; Corsini, GU; Fascetti, F; Fornai, F; Tedeschi, D; Vaglini, F1
García-Ruiz, PJ; Jiménez-Jiménez, FJ1
Antkiewicz-Michaluk, L; Herman, ZS; Obuchowicz, E; Romańska, I1
Baker, GB; Holt, A; Todd, KG1
Osland, ST; Pringsheim, T; Steeves, TD1

Reviews

4 review(s) available for clonidine and selegiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette's syndrome.
    Advances in neurology, 1995, Volume: 65

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Clonidine; Comorbidity; Dextroamphetamine; Guanfacine; Humans; Learning Disabilities; Methylphenidate; Pemoline; Selegiline; Tourette Syndrome

1995
Pharmacological options for the treatment of Tourette's disorder.
    Drugs, 2001, Volume: 61, Issue:15

    Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Conduct Disorder; Dopamine Antagonists; Humans; Monoamine Oxidase Inhibitors; Selegiline; Tourette Syndrome

2001
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
    The Cochrane database of systematic reviews, 2018, 06-26, Volume: 6

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Clonidine; Desipramine; Dextroamphetamine; Female; Guanfacine; Humans; Male; Methylphenidate; Randomized Controlled Trials as Topic; Selegiline; Tic Disorders

2018

Other Studies

15 other study(ies) available for clonidine and selegiline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
    Bioorganic & medicinal chemistry, 2016, 10-15, Volume: 24, Issue:20

    Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship

2016
Amine oxidase released into plasma of rats treated with hepatotoxin allyl formate.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Clonidine; Formates; Formic Acid Esters; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; Monoamine Oxidase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Phenelzine; Rats; Rats, Inbred Strains; Selegiline; Semicarbazides

1989
Serotoninergic but not noradrenergic neurons in rat central nervous system adapt to long-term treatment with monoamine oxidase inhibitors.
    Neuroscience, 1985, Volume: 16, Issue:4

    Topics: Animals; Clonidine; Clorgyline; Locus Coeruleus; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Phenelzine; Raphe Nuclei; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Synaptic Transmission

1985
A behavioural and neurochemical analysis of chronic and selective monoamine oxidase inhibition.
    Psychopharmacology, 1987, Volume: 92, Issue:1

    Topics: Animals; Behavior, Animal; Brain Chemistry; Clonidine; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Selegiline; Self Stimulation

1987
Striatal MPP+ levels do not necessarily correlate with striatal dopamine levels after MPTP treatment in mice.
    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetaldehyde; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Ditiocarb; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nicotine; Piperazines; Selegiline; Serotonin

1996
Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Dopamine; Homovanillic Acid; Immunohistochemistry; Levodopa; Male; Mice; MPTP Poisoning; Neuropeptide Y; Neuroprotective Agents; Selegiline; Serotonin

2003
The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Adrenergic alpha-Agonists; Allyl Compounds; Amine Oxidase (Copper-Containing); Animals; Brain; Cell Membrane; Clonidine; Clorgyline; Drug Combinations; Guanidines; Imidazoline Receptors; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Selegiline

2003