Compounds > clonidine

clonidine and rofecoxib

clonidine has been researched along with rofecoxib in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Agrawal, H; Dhaneshwar, SR; Kakad, A; Kaul, N; Patil, B1
Gandhimathi, M; Ravi, TK; Varghese, SJ1
Bertoli, R; Caduff Janosa, P; Cerny, A; Kick, A; Moschovitis, G1
Backman, JT; Karjalainen, MJ; Laitila, J; Neuvonen, M; Neuvonen, PJ1

Trials

1 trial(s) available for clonidine and rofecoxib

ArticleYear
Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects.
    British journal of clinical pharmacology, 2006, Volume: 62, Issue:3

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Clonidine; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP1A2 Inhibitors; Double-Blind Method; Drug Interactions; Humans; Lactones; Male; Sulfones

2006

Other Studies

6 other study(ies) available for clonidine and rofecoxib

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Application of HPLC and HPTLC for the simultaneous determination of tizanidine and rofecoxib in pharmaceutical dosage form.
    Journal of pharmaceutical and biomedical analysis, 2005, Feb-07, Volume: 37, Issue:1

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clonidine; Dosage Forms; Lactones; Sulfones

2005
Simultaneous LC determination of tizanidine and rofecoxib in tablets.
    Journal of pharmaceutical and biomedical analysis, 2005, Feb-07, Volume: 37, Issue:1

    Topics: Chemistry, Pharmaceutical; Chromatography, Liquid; Clonidine; Drug Combinations; Lactones; Sulfones

2005
[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)].
    Medizinische Klinik (Munich, Germany : 1983), 2005, Apr-15, Volume: 100, Issue:4

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Clonidine; Cyclooxygenase Inhibitors; Drug Interactions; Electrocardiography; Emergencies; Female; Heart Failure; Hospitalization; Humans; Lactones; Length of Stay; Low Back Pain; Middle Aged; Sulfones

2005