clonidine and pyrilamine

clonidine has been researched along with pyrilamine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's2 (11.76)18.2507
2000's3 (17.65)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, TH; Ganellin, CR; Griffiths, R; Jones, M; Mitchell, RC; Rana, KK; Saunders, D; Smith, IR; Sore, NE; Young, RC1
Andrews, PR; Craik, DJ; Martin, JL1
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Ahman, M; Holmén, AG; Wan, H1
Bökesoy, TA; Ercan, ZS; Ersoy, F; Türker, RK; Zengil, H1
Lisciani, R; Silvestrini, B1
Finch, L; Hicks, PE1
Fozard, JR1
Livingston, A; Nolan, A; Waterman, A1
Kawasaki, H; Takasaki, K1
Seybold, VS; Wilcox, BJ1
Robinson, BV1
Berlan, M; Carpene, C; Dang Tran, L; Lafontan, M1
Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T1
Kubo, Y1

Reviews

1 review(s) available for clonidine and pyrilamine

ArticleYear
[Carrier-mediated Transport of Cationic Drugs across the Blood-Tissue Barrier].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:10

    Topics: Angiogenesis Inhibitors; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Cation Transport Proteins; Clonidine; Drug Carriers; Humans; Nervous System Diseases; Neuroprotective Agents; Propranolol; Pyrilamine; Verapamil

2015

Other Studies

16 other study(ies) available for clonidine and pyrilamine

ArticleYear
Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Algorithms; Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry, Physical; Clonidine; Guinea Pigs; Histamine H2 Antagonists; Imipramine; Pyrilamine; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Possible involvement of endogenous histamine in the myotropic effect of clonidine on the isolated rabbit aorta.
    Agents and actions, 1978, Volume: 8, Issue:5

    Topics: Amine Oxidase (Copper-Containing); Animals; Aorta, Thoracic; Blood Vessels; Clonidine; Female; Histamine; Histidine Decarboxylase; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Pyrilamine; Rabbits

1978
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice, Inbred Strains; Nicotine; Oxotremorine; Parkinson Disease, Secondary; Phenoxybenzamine; Piloerection; Pyrilamine; Rabbits; Salivation; Sympathetic Nervous System; Trazodone; Tremor

1976
No evidence for central histamine-receptor involvement with the hypotensive effect of clonidine in cats.
    European journal of pharmacology, 1976, Volume: 40, Issue:2

    Topics: Animals; Behavior, Animal; Blood Pressure; Cats; Clonidine; Injections, Intraventricular; Metiamide; Phentolamine; Procaine; Pyrilamine; Receptors, Histamine; Tolazoline

1976
Comparative effects of four migraine prophylactic drugs on an isolated extracranial artery.
    European journal of pharmacology, 1976, Volume: 36, Issue:1

    Topics: Animals; Carotid Artery, External; Chlorides; Clonidine; Cyproheptadine; Drug Interactions; Histamine; Methysergide; Norepinephrine; Phentolamine; Pizotyline; Potassium; Pyrilamine; Rabbits; Serotonin; Thiophenes; Tryptamines; Tyramine; Vasoconstrictor Agents

1976
The effects of alpha 2 adrenoceptor agonists on airway pressure in anaesthetized sheep.
    Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Airway Resistance; Animals; Clonidine; Dioxanes; Female; Histamine; Idazoxan; Injections, Intravenous; Injections, Intraventricular; Methoxamine; Prazosin; Pyrilamine; Sheep; Tripelennamine; Xylazine

1986
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1986
Distribution of neurotransmitter binding sites in the cat median eminence.
    Neuroendocrinology, 1987, Volume: 46, Issue:1

    Topics: Animals; Autoradiography; Cats; Clonidine; Lysergic Acid Diethylamide; Median Eminence; Pyrilamine; Quinuclidinyl Benzilate; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Muscarinic; Receptors, Serotonin

1987
Histamine receptor agonists and antagonists on granulocyte adherence.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:7

    Topics: Cimetidine; Clonidine; Granulocytes; Histamine; Histamine Antagonists; Humans; Pyrilamine

1982
Clonidine-induced lipolysis in dog adipocytes by stimulation of histamine (H2)-receptors.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 249, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Clonidine; Dogs; Histamine; Lipolysis; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Theophylline

1981
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:3

    Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine

2004