clonidine has been researched along with prazosin in 855 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 464 (54.27) | 18.7374 |
| 1990's | 265 (30.99) | 18.2507 |
| 2000's | 94 (10.99) | 29.6817 |
| 2010's | 32 (3.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, RC; Chapleo, CB; England, DC; Myers, PL; Roach, AG; Smith, CF; Stillings, MR; Tulloch, IF | 1 |
| Haubrich, DR; Hlasta, DJ; Luttinger, D; Perrone, MH; Silbernagel, MJ; Ward, SJ | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Daenzer, C; Harris, DW; Humphrey, SJ; Kamdar, BV; McCall, JM; McCall, RB; Sethy, VH; TenBrink, RE | 1 |
| Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF | 1 |
| Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Timmermans, PB; van Zwieten, PA | 2 |
| Bandurco, VT; Hajos, ZG; Levine, SD; Wong, EM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Bednarski, M; Dudek, M; Kulig, K; Lustyk, K; Malawska, B; Nowiński, L; Raźny, K; Sapa, J; Siwek, A; Starowicz, G; Zaręba, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Nies, AS | 1 |
| Pettinger, WA | 1 |
| Oparil, S; Rick, JH | 1 |
| Doxey, JC; Smith, CF; Walker, JM | 1 |
| Gain, JM; Mahony, JF; Raftos, J; Stewart, JH; Stokes, GS | 1 |
| Gifford, RW; Tarazi, RC; Wollam, GL | 1 |
| Klien, W | 1 |
| Sterz, H | 1 |
| Charness, ME; Robertson, D; Snyder, SH; U'Prichard, DC | 1 |
| Lam, E; Timmermans, PB; van Zwieten, PA | 2 |
| Baietti, M; Carletta, C; Liuti, G; Mancinella, A; Paolucci, M | 1 |
| Kuchel, OG; Mahon, WA; McKenzie, JK; Ogilvie, RI | 1 |
| Commarato, MA; Dugan, DH; Kaplan, HR; Langley, AE; Lattime, EC; Smith, RD; Tessman, DK | 1 |
| Glossmann, H; Hornung, R; Presek, P | 1 |
| Enenkel, W | 1 |
| Cybulska, I | 1 |
| Sternon, J | 1 |
| Cavero, I; Lefèvre, F; Roach, AG | 2 |
| Dausse, J; Meyer, P; Miach, PJ | 1 |
| Constantine, JW; McShane, WK; Weeks, RA | 1 |
| Riddiough, MA | 1 |
| Fernandes, M; Onesti, G | 1 |
| Kontro, J; Kyöstilä, S; Mattila, MJ; Pitkäjärvi, T | 1 |
| Hammond, JJ; Kirkendall, WM; Overturf, ML; Thomas, JC; Zama, A | 1 |
| Gantt, CL | 1 |
| Schumacher, GE | 1 |
| Moser, M | 1 |
| Kuokkanen, K; Mattila, MJ | 1 |
| Lemaire, S; Magnan, J; Quirion, R; Regoli, D; Rioux, F; St-Pierre, S | 1 |
| Bartholini, G; Dubocovich, ML; Langer, SZ; Pelayo, F; Scatton, B | 1 |
| Cavero, I; Dennis, T; Lefèvre-Borg, F; Perrot, P; Roach, AG; Scatton, B | 1 |
| Baumann, N; Chermat, R; Lachapelle, F; Simon, P | 1 |
| Roba, J; van Dorsser, W | 1 |
| Cavero, I; Roach, AG | 2 |
| Finnerty, FA | 2 |
| Grenfell, RF | 1 |
| Bradley, ME; Buxton, IL; Keef, KD; Zhang, L | 1 |
| Mallard, NJ; Marshall, RW; Sithers, AJ; Spriggs, TL | 1 |
| Chan, CB; MacPhail, RM | 1 |
| Bento, AC; de Moraes, S | 1 |
| Brading, AF; Chen, HI | 1 |
| Etgen, AM; Karkanias, GB; Petitti, N | 1 |
| Arunachalam, KD; Loomis, CW | 1 |
| Kawasaki, H; Nakamura, S; Takasaki, K | 1 |
| Alam, MN; Mallick, BN | 2 |
| Kojima, C; Satoh, M; Takayanagi, I | 2 |
| Chen, YM; Han, QD | 1 |
| Elhawary, AM; Pettinger, WA; Wolff, DW | 1 |
| Okuma, Y; Osumi, Y; Yokotani, K | 2 |
| Saeki, S; Yaksh, TL | 1 |
| Fukado, Y; Iizuka, T; Inatomi, M; Koide, R; Masaoka, Y; Moriwaki, Y; Nakamura, A; Nakata, K; Uchida, E; Ueda, T | 1 |
| Carlson, DE; Gann, DS | 1 |
| Enero, MA; Ricci, D; Taira, CA | 1 |
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Berridge, TL; Doxey, JC; Roach, AG; Smith, CF | 1 |
| Berrino, L; Lampa, E; Maione, S; Rossi, F; Vitagliano, S | 1 |
| Jansen van't Land, C; van der Laan, JW | 1 |
| Piascik, MT; Pruitt, TA; Sparks, MS | 2 |
| Blue, DR; Clarke, DE; Vimont, RL | 1 |
| Hayakawa, H; Shimizu, M; Yamawaki, S | 1 |
| Sperlágh, B; Vizi, ES | 1 |
| Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Su, C; Su, S; Zheng, S | 1 |
| Koman, LA; Smith, TL | 1 |
| Altiere, RJ; Diamond, L; Thompson, DC | 2 |
| Akaike, M; Hirai, M; Kumai, T; Masubuchi, Y; Tanaka, M; Watanabe, M | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Kempf, J; Molines, A; Stutzman, J | 1 |
| Tao, JY; Wang, P; Xu, SY | 1 |
| Borbujo, J; Diéguez, G; García, JL; García-Villalón, AL; Gómez, B; Nava-Hernández, E; Valle, J | 1 |
| Drouva, SV; Faivre-Bauman, A; Kordon, C; Laplante, E; Loudes, C | 1 |
| Schultheiss, A; Starke, K; Szabo, B | 1 |
| García-Barrado, MJ; Moratinos, J; Reverte, M | 2 |
| Basso, A; Piantanelli, L; Rossolini, G; Viticchi, C; Zaia, A | 1 |
| Mori-Okamoto, J; Namii, Y; Tatsuno, J | 1 |
| Muramatsu, I | 1 |
| Breschi, MC; Ciucci, MA; Martinotti, E; Nieri, P; Omini, C; Pani, M | 1 |
| Cervo, L; Samanin, R | 1 |
| Abel, PW; Feng, F; Jeffries, WB; Pettinger, WA | 1 |
| García-Sáinz, JA; Torres-Márquez, ME; Villalobos-Molina, R | 1 |
| Kigoshi, S; Muramatsu, I; Yamanaka, K | 2 |
| Chandler, SH; Katakura, N | 1 |
| Brien, JF; Marks, GS; Nakatsu, K; Pym, J; Witte, S | 1 |
| Piascik, MT; Pruitt, TA; Soltis, EE; Sparks, MS | 1 |
| Guenaneche, F; Lefebvre, RA; Schuurkes, JA | 1 |
| Kinami, J; Maruyama, K; Nagatomo, T; Sugita, Y; Sugiyama, E; Takada, Y; Tsuchihashi, H | 1 |
| Endoh, M; Norota, I; Takanashi, M | 1 |
| Bojö, L; Cassuto, J; Nellgård, P | 1 |
| Nicholson, T; Osman, TE | 1 |
| Atlas, D; Manolopoulos, VG; Pipili-Synetos, E; Synetos, D | 1 |
| Bourin, M; Bradwejn, J; Hascoët, M | 1 |
| Collewijn, H; Pompeiano, O; Tan, HS; van Neerven, J | 1 |
| Mante, S; Minneman, KP | 1 |
| Kigoshi, S; Muramatsu, I; Oshita, M | 3 |
| Awad, IR; Finkelstein, JA; Gearhart, GM; Jhanwar-Uniyal, M; Leibowitz, SF | 1 |
| Abebe, W; Harris, KH; MacLeod, KM | 1 |
| Clark, DW; Curzio, JL; Howie, CA; Reid, JL | 1 |
| Janssen, BJ; Struyker-Boudier, HA; Tyssen, CM | 1 |
| Fukuda, H; Mishima, A; Ono, H; Ono, S; Vasko, MR | 1 |
| Pittaluga, A; Raiteri, M; Torelli, R | 1 |
| Foo, H; Westbrook, RF | 1 |
| Baranova, OS; Dergacheva, IuG; Kharchenko, VI; Kiseleva, NG; Nasedkin, VS; Pashedko, MA; Petraneva, EV; Tebloev, KI | 1 |
| Bell, K; Insel, PA; Klijn, K; Slivka, SR | 1 |
| Ramage, AG | 1 |
| Markel', AL; Naumenko, EV; Shishkina, GT | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H | 1 |
| Elverdin, JC; Kaniucki, MO; Perec, CJ; Stefano, FJ | 1 |
| Nakajima, M; Ueda, M | 1 |
| Palmeri, A; Wiesendanger, M | 1 |
| Klement, G; Leenen, FH | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Danzebrink, RM; Gebhart, GF | 1 |
| Hashimoto, K; Hayashi, M; Tanii, H | 1 |
| Chandranath, SI; Gokhale, SD; Sharif, SI | 1 |
| Ferrari, RA; Hamel, LT; Haubrich, DR; Perrone, MH | 1 |
| Butler, BT; Kusiak, JW; Piascik, MT; Pruitt, TA | 1 |
| Terman, BI | 1 |
| Assenmacher, I; Barbanel, G; Gaillet, S; Malaval, F; Szafarczyk, A | 1 |
| Horn, PT; Kohli, JD; Mercuro, G; Orelind, ER | 1 |
| Ferrier, GR; Han, XQ | 1 |
| Casebolt, TL; Jope, RS; Li, XH | 1 |
| Ayajiki, K; Toda, N | 1 |
| Andrioli, GC; Cavazzani, P; Folghera, S; Göthert, M; Maura, G; Raiteri, M; Schalnus, R; Schlicker, E | 1 |
| Reis, CC | 1 |
| Hertz, L; Subbarao, KV | 1 |
| Burnstock, G; Ellis, JL; Kasakov, L; Vlaskovska, M | 1 |
| Endo, T; Hashimoto, K; Onaya, T; Shimura, H; Tsujimoto, G; Watanabe, K | 1 |
| Levin, BE | 1 |
| Arce, V; Cavanus, S; Cella, SG; Mennini, T; Miari, A; Müller, EE | 1 |
| Butler, BT; Piascik, MT; Pruitt, TA | 1 |
| Rattan, S; Yamato, S | 1 |
| Minneman, KP; Wilson, KM | 1 |
| Camargo, LA; Colombari, E; De Luca Júnior, LA; Menani, JV; Renzi, A; Saad, WA | 1 |
| Culp, DJ; Graham, LA; Marin, MG; McBride, RK | 1 |
| Egan, BM; Neubig, RR; Sekkarie, MA; Supiano, MA | 1 |
| Klaassen, AB; Rodrigues de Miranda, JF; Van Ginneken, CA; Van Megen, YJ; Wentges, BT | 1 |
| Berlan, M; Estan, L; Montastruc, JL; Senard, JM; Tran, MA | 1 |
| Fukuda, H; Ono, H; Tanabe, M | 1 |
| Camargo, LA; De Luca Junior, LA; Ferrari, AC; Menani, JV; Renzi, A; Saad, WA | 1 |
| Dunn, AJ; Gorman, AL; Yang, XM | 1 |
| Bian, RL; Lin, B; Mao, LG; Zhao, MH; Zheng, XF | 1 |
| Jacobs, BL; Stafford, IL | 1 |
| Pezzola, A; Popoli, P; Scotti de Carolis, A | 1 |
| Berridge, CW; Dunn, AJ | 2 |
| Henke, PG; Ray, A; Sullivan, RM | 1 |
| Bevan, JA; Oriowo, MA | 1 |
| Bugajski, J; Gadek-Michalska, A; Połczyńska-Konior, G; Turoń, M | 1 |
| Koss, MC | 1 |
| Glavin, GB; Penner, SB; Smyth, DD | 1 |
| Masuda, Y; Mollace, V; Nisticò, G; Pelaggi, T | 1 |
| Imai, S; Nakahara, H; Nakazawa, M; Tsukada, T | 1 |
| Chin, WP; Imai, S; Nakagawa, Y; Nakahara, H | 1 |
| Lepor, H; Shapiro, E | 1 |
| Jones, RS; Olpe, HR | 1 |
| Dresse, A; Scuvée-Moreau, J | 1 |
| Majewski, H; Rump, LC | 1 |
| Anavekar, SN; Conway, EL; Drummer, OH; Howes, LG; Jarrott, B; Louis, WJ; McNeil, JJ; Workman, B | 1 |
| Coffman, JD; Cohen, RA | 2 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
| Hester, RK; Satake, N; Shibata, S | 1 |
| Ashizawa, N; Hayashi, E; Nakayama, K; Tomita, T; Yamada, S | 1 |
| Li, DX; Shen, GS | 1 |
| Klepzig, M; Motz, W; Strauer, BE | 1 |
| Bennett, GW; Fone, KC; Heal, DJ; Johnson, JV; Marsden, CA | 1 |
| Järvinen, A; Paakkari, I | 1 |
| Kazmi, SM; Mishra, RK | 1 |
| Anderson, RJ; Dillingham, MA | 1 |
| Felder, RB; Feldman, PD | 2 |
| Fiszman, ML; Luchelli-Fortis, MA; Stefano, FJ | 1 |
| Kawasaki, H; Takasaki, K; Urabe, M | 1 |
| Crea, F; Galassi, AR; Kaski, JC; Maseri, A; Pupita, G; Vejar, M | 1 |
| Leighton, HJ; Ramagopal, MV | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Simonato, M; Spalluto, P; Tanganelli, S; Tomasini, C | 1 |
| Chapelain, B; Gargouil, YM; Mahe, L; Neliat, G | 1 |
| Koshiura, R; Miyamoto, K; Sanae, F | 2 |
| Majewski, H; Murphy, TV | 1 |
| Fowler, CJ; O'Neill, C; Winblad, B | 1 |
| Brasili, L; Giardinà, D; Gregori, M; Massi, M; Melchiorre, C; Picchio, MT; Quaglia, W | 1 |
| Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Chernesky, CE; Chou, TC; Felsen, D; Marion, DN; Somers, WJ; Vaughan, ED | 1 |
| Auclair, MC; Lavau, M; Lechat, P; Vernimmen, C | 1 |
| Bowersox, S; Ciaranello, R; Dement, WC; Frusthofer, B; Guilleminault, C; Maddaluno, J; Mignot, E; Nishino, S | 1 |
| Nagatomo, T; Tsuchihashi, H | 1 |
| Enna, SJ; Nomura, S; Pilc, A; Vetulani, J | 1 |
| Kondo, S; Latifpour, J; Morita, T; O'Hollaren, B; Weiss, RM | 1 |
| Sanger, DJ | 1 |
| Badia, A; Sallés, J | 2 |
| Ladwein, E; Szrama, E; Wessler, I | 1 |
| Lloyd, RL; Menon, MK | 1 |
| Batts, J; Branche, G; Brown, J; Dowdy, V; King, A; Streets, M | 1 |
| Cerný, J; Dolezel, S; Dostál, M; Guba, P; Petrzilka, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Cardinali, DP; Chuluyan, HE; Rosenstein, RE | 1 |
| Cerný, J; Dostál, M; Gregor, Z; Guba, P; Rebícek, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Carenzi, A; Chiarino, D; Napoletano, M; Reggiani, A; Sala, A; Sala, R | 1 |
| Butkhuzi, SM; Kolchin, VV; Moroz, BT; Sakvarelidze, ZA; Zaĭtsev, AA | 1 |
| Morita, T; Suzuki, T; Tsuchida, S; Wada, I | 1 |
| Giesen-Crouse, E; Imbs, JL; Krieger, JP; Schmidt, M | 1 |
| Baumann, M; Lepor, H; Shapiro, E | 1 |
| Baldwin, JJ; deSolms, SJ; Guare, JP; Huff, JR; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM | 1 |
| Frambach, DA; Valentine, JL; Weiter, JJ | 1 |
| Feder, HH; Johnson, AE; McEwen, BS; Nock, B | 2 |
| Jones, DJ; Simmons, RM | 1 |
| Carpene, C; de Pablos, I; Moratinos, J; Reverte, M | 1 |
| Hori, M; Inoue, M; Iwai, K; Iwakura, K; Kagiya, T; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Jiang, Q; Porreca, F; Sheldon, RJ | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Rando, S; Simonato, M; Tanganelli, S | 1 |
| Berndt, WO; Jensen, RE | 1 |
| Bonacci, F; De Sarro, GB; Nisticò, G | 1 |
| Gallager, D; Goldman-Rakic, PS; Rakic, P | 1 |
| Armah, BI | 1 |
| Bezachev, VG; Gertsov, GE; Kulinskiĭ, VI; Plotnikov, NIu | 1 |
| Blandford, DE; Smyth, DD | 1 |
| Fujiwara, Y; Kazahaya, Y; Otsuki, S; Sandyk, R; Takeda, T | 1 |
| Maura, G; Pittaluga, A; Raiteri, M; Ulivi, M | 1 |
| Müller, WE; Rick-Brand, S | 1 |
| Carrier, GO; White, RE | 2 |
| Man in't Veld, AJ; Schalekamp, MA | 1 |
| Kobinger, W; Pichler, L | 2 |
| Agid, Y; Cash, R; Raisman, R; Ruberg, M | 2 |
| Furnace, G; Hamilton, CA; Reid, JL; Sumner, DJ | 1 |
| Biollaz, B; Biollaz, J; Gavras, H; Gavras, I; Kohlmann, O | 1 |
| Kärki, NT; Puurunen, J; Ruskoaho, H; Savola, JM | 1 |
| Nobin, A; Owman, C; Törnebrandt, K | 1 |
| Anderson, S; Brater, DC; Graham, RM | 1 |
| DeMarinis, RM; Lefkowitz, RJ; Regan, JW | 1 |
| Jones, CE; Liang, IY | 1 |
| Blayac, JP; Gross, R; Hillaire-Buys, D; Loubatières-Mariani, MM; Ribes, G | 1 |
| de Jonge, A; Qian, JQ; Thoolen, MJ; Timmermans, PB; van den Berg, G; van Zwieten, PA; Wilffert, B | 1 |
| Baggio, G; Ferrari, F; Martinelli, R | 1 |
| Anderson, RJ; Reed, WG | 1 |
| Honda, K; Miyata-Osawa, A; Takenaka, T; Terai, M | 1 |
| Campbell, IC; McKernan, RM | 2 |
| Offermeier, J; Rossouw, J; van Rooyen, JM | 1 |
| Reid, JL | 1 |
| Fujii, M; Hamada, Y; Kasuya, Y; Nakamura, M; Ohira, A; Shigenobu, K; Wada, Y | 1 |
| Graf, B; Urbaszek, W | 1 |
| de Jonge, A; Jonkman, FA; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Kaniucki, MD; Perec, CJ; Stefano, FJ | 1 |
| Herman, G; Mauduit, P; Rossignol, B | 1 |
| Kitazawa, T; Kondo, H; Temma, K | 1 |
| Smith, PJ; Talbert, RL | 1 |
| Livingston, A; Nolan, A; Waterman, A | 1 |
| Coviello, A; Gamundi, SS; Scheucher, A | 1 |
| Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Martin, GE; Pettibone, DJ; Randall, WC; Vacca, J | 1 |
| Macedo, TA; Ribeiro, CA | 1 |
| Hicks, PE; Langer, SZ; Najar, M; Vidal, M | 1 |
| Kubo, T; Misu, Y; Nagura, J | 1 |
| Bousquet, P; Feldman, J | 1 |
| Cella, SG; De Gennaro, V; Locatelli, V; Müller, EE; Wehrenberg, WB | 1 |
| Ahrén, B; Lundquist, I; Skoglund, G | 1 |
| Ascioti, C; De Sarro, GB; Froio, F; Libri, V; Nisticò, G | 1 |
| Harris, JC; Newman, JD | 1 |
| Hanazuka, M; Nishi, H; Watanabe, T; Yuki, S | 1 |
| Yuwiler, A | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Crepel, F; Debono, M; Flores, R | 1 |
| Breschi, MC; Ducci, M; Fantoni, B; Martinotti, E | 1 |
| Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Pettibone, DJ; Randall, WC; Vacca, J; Young, SD | 1 |
| Baines, AD | 1 |
| Döhler, KD; Geerlings, H; Jarzab, B; Sickmöller, PM | 1 |
| Bianchetti, M; Chen, DF; Wiesendanger, M | 1 |
| Dresse, A; Scuvée-Moreau, J; Seutin, V | 1 |
| Campbell, SF; Danilewicz, JC; Greengrass, CW; Plews, RM | 1 |
| Feldman, PD; Moises, HC | 1 |
| Penner, SB; Smyth, DD | 1 |
| Cheng, B; Fang, DC; Jiang, MX; Yao, WX | 1 |
| Bourreau, JP; Tricoche, R | 1 |
| Cummings, S; Seybold, V | 1 |
| Nyman, L; Saano, V; Savola, JM; Virtanen, R | 1 |
| Aono, J; Nagatomo, T; Nakamura, T; Tajiri, A; Tsuchihashi, H | 1 |
| Furuta, T | 1 |
| Junnarkar, AY; Singh, PP | 1 |
| Allen, JM; McCarron, JG; McHale, NG; Thornbury, KD | 1 |
| Fitten, J; Gordon, LI; Menon, MK | 1 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Horie, Y; Koike, K; Nakamura, M; Takayanagi, I | 1 |
| Engel, J; Hård, E; Lindh, AS | 1 |
| Aono, J; Sakai, K | 1 |
| Appia, F; Chariot, J; del Tacca, M; Rozé, C; Tsocas, A | 1 |
| Calvillo, O; Ghignone, M; Madrid, J | 1 |
| Heitz, C; Jung, L; Schott, C; Stambach, JF; Stoclet, JC; Tetsi, L | 1 |
| Dirksen, R; Van der Laan, JW | 1 |
| Docherty, JR | 1 |
| Good, AP; Leier, CV; Unverferth, DV | 1 |
| Strauer, BE | 1 |
| Akopian, LM; Basem, AS; Ivleva, AIa; Krasnobaeva, GM; Moiseev, VS | 1 |
| Decker, N; Schwartz, J | 1 |
| Messick, K; Ruffolo, RR | 1 |
| Consolo, S; Forloni, GL; Ladinsky, H; Vinci, R; Wang, JX | 1 |
| Nyman, L; Virtanen, R | 1 |
| Antkiewicz-Michaluk, L; Vetulani, J | 1 |
| Batink, HD; de Jonge, A; Graf, E; Mathy, MJ; Prop, G; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Bylund, DB | 1 |
| Agid, Y; Cash, R; Lasbennes, F; Sercombe, R; Seylaz, J | 1 |
| Clark, JT; Davidson, JM; Smith, ER | 1 |
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| Bojö, L; Cassuto, J; Jönsson, A; Nellgård, P | 1 |
| Calixto, JB; Filho, VC; Santos, AR; Yunes, RA | 1 |
| Barman, SM; Gebber, GL; Orer, HS; Zhong, S | 1 |
| Bouysset, F; Cordi, AA; Laubie, M; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
| Mozaffari, MS; Roysommuti, S; Wyss, JM | 1 |
| Puumala, T; Riekkinen, P; Ruotsalainen, S; Sirviö, J | 1 |
| Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
| Miranda, HF; Naquira, D; Pinardi, G; Sierralta, F | 1 |
| Akaishi, Y; Hattori, Y; Kanno, M; Nagashima, M | 1 |
| Intengan, HD; Smyth, DD | 1 |
| Dowlatshahi, P; Yaksh, TL | 1 |
| Camargo, GP; Camargo, LA; Saad, WA | 1 |
| Homuth, V; Luther, HP; Wallukat, G | 1 |
| Puumala, T; Sirviö, J | 1 |
| Puumala, T; Riekkinen, P; Sirviö, J | 1 |
| Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Dyer, DC; Hu, XQ | 1 |
| Guimarães, S; Paiva, MQ; Pereira, O | 1 |
| Gwak, YS; Leem, JW; Nam, TS; Paik, KS | 1 |
| Macmillan, JB; McGrath, JC; Smith, KM | 1 |
| Daniel, EE; Gaspar, V; Kwan, CY; Low, AM; Lu-Chao, H | 1 |
| Jentsch, JD; Katz, Z; Roth, RH; Wise, A | 1 |
| Duda, T; Sharma, RK; Venkataraman, V | 1 |
| Greijus, S; Haapalinna, A; Narinen, K; Puumala, T; Riekkinen, P; Sirviö, J | 1 |
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| Wong, KK | 1 |
| Brown, RD; Daniel, EE; Kwan, CY; Low, AM; Lu-Chao, H; Wang, YF | 1 |
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| Demenge, P; Godin-Ribuot, D; Joyeux, M; Patel, A; Ribuot, C; Yellon, DM | 1 |
| Altenburg, SP; Farah, MB | 1 |
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| Errasti, AE; Rothlin, RP; Sardi, SP; Torres, RM; Velo, MP | 1 |
| Amobi, N; Coker, C; Guillebaud, J; Mulvin, D; Smith, IC | 1 |
| Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ | 1 |
| Barna, I; Kiem, DT; Makara, GB; Zelena, D | 1 |
| Centurión, D; De Vries, P; Rabelo, G; Sánchez-López, A; Saxena, P; Villalón, CM | 1 |
| Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T | 1 |
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| Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
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| Brechet, S; Chayvialle, JA; Claustre, J; Cuber, JC; Plaisancie, P | 1 |
| Akagi, Y; Muramatsu, I; Nakamura, S; Suzuki, F; Taniguchi, T | 1 |
| Luthy, IA; Pignataro, O; Vázquez, SM | 1 |
| Nott, MW; Rand, MJ; Thaina, P | 1 |
| Avellar, MC; Megale, A; Porto, CS; Silva, MA | 1 |
| Castro, JL; Ramirez, A; Ricci, D; Taira, CA | 1 |
| Arias-Montaño, JA; Berger, VA; Soria-Jasso, LE; Young, JM | 1 |
| Brotchie, JM; Hill, MP | 1 |
| Antzelevitch, C; Burashnikov, A | 1 |
| Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K | 1 |
| Bischoff, FP; Braeken, M; Kennis, LE; Leysen, JE; Love, CJ; Megens, AA; Mertens, CJ; Pieters, S; Van den Keybus, FA | 1 |
| Delgado, C; Martínez, ML | 1 |
| Lutz, EA; Shannon, HE | 1 |
| Benamour, K; Chang-Fong, J; Cussac, M; Morand, JM; Szymonski, B; Thomasson, F | 1 |
| Mozaffari, MS; Patel, C; Schaffer, SW; Warren, BK | 1 |
| de Arruda Camargo, LA; dos Santos, TA; Ferreira, AC; Guarda, IF; Neto, AF; Saad, WA | 1 |
| Babaie, A; Etminani, A; Gharib, B; Homayoun, H; Zarrindast, MR | 1 |
| Chen, PC; Cheng, JT; Liu, IM; Yen, ST | 1 |
| Harkin, A; Kelly, JP; Leonard, BE; Morris, K; O'Donnell, JM | 1 |
| Gaivin, RJ; Gonzalez-Cabrera, P; Perez, DM; Ross, SA; Waugh, DJ; Yun, J; Zuscik, MJ | 1 |
| Kawahara, H; Kawahara, Y; Westerink, BH | 1 |
| Coats, P; Hillier, C; Jarajapu, YP; MacDonald, A; McGrath, JC | 1 |
| Hillier, C; Jarajapu, YP; MacDonald, A | 1 |
| Miranda, HF; Pinardi, G; Sierralta, F | 2 |
| Koike, K; Yamamoto, Y | 1 |
| Dlaboga, D; Dziedzicka-Wasylewska, M; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Chiba, S; Taguchi, Y; Yang, XP | 1 |
| Sugimoto, M; Uchida-Oka, N | 1 |
| Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Alarcón, P; García-Sancho, J; Núñez, L | 1 |
| D'Ocon, P; Gisbert, R; Ivorra, MD; Noguera, MA; Ziani, K | 1 |
| Sahebgharani, M; Zarrindast, MR | 1 |
| Li, DP; Pan, HL; Pan, YZ | 1 |
| Hashimoto, K; Hirasawa, A; Sugawara, T; Tsujimoto, G | 1 |
| Montastruc, JL; Pelat, M; Senard, JM; Tran, MA; Verwaerde, P | 1 |
| Greger, R; Herbst, M; Hescheler, J; Sasse, P; Ullrich, S; Yu, H | 1 |
| Katus, HA; Kemken, D; Kurz, T; Mier, K; Richardt, G | 1 |
| Drummond, PD | 2 |
| Brodde, OE; Dhein, S; Giessler, C; Silber, RE; Wangemann, T | 1 |
| Camargo, LA; Guarda, IF; Saad, WA; Santos, TA; Simões, S | 1 |
| Hadi, M; Homayoun, H; Khavandgar, S; Postami, P; Shafaghi, B; Zarrindast, MR | 1 |
| Longmore, J; Razzaque, Z; Scott, P | 1 |
| Chaturapanich, G; Maythaarttaphong, S; Pholpramool, C; Verawatnapakul, V | 1 |
| Lähdesmäki, J; Ozdoğan, UK; Scheinin, M | 1 |
| Hillard, CJ; Patel, S | 1 |
| Archer, T; Fredriksson, A | 1 |
| Carro-Juáreza, M; Rodríguez-Manzo, G | 1 |
| Ghiasvand, M; Homayoun, H; Khavandgar, S; Rostami, P; Shafaghi, B; Zarrindast, MR | 1 |
| Lee, S; Rivier, C; Seo, DO | 1 |
| Beemster, P; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Campos, M; Morais, Pde L; Pupo, AS | 1 |
| Cremers, TI; Pudovkina, OL; Westerink, BH | 1 |
| Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Guo, S; Hisamitsu, T; Jiao, Y; Umezawa, T | 1 |
| Chlopicki, S; Gryglewski, RJ; Kozlovski, VI | 1 |
| Collier, KS; Collier, TJ; Felten, DL; Greene, JG; Stevens, SY | 1 |
| Brock, JA; McLachlan, EM; Yeoh, M | 1 |
| Hillier, C; MacDonald, A; Zacharia, J | 2 |
| Gokee, A; Rocchini, AP; Yang, JQ | 1 |
| Eltze, M; Jähnichen, S; Pertz, HH | 1 |
| Frisbee, JC | 1 |
| Adir, Y; Azzam, ZS; Comellas, A; Crespo, A; Dada, LA; Krivoy, N; Lecuona, E; Ridge, KM; Rutschman, DH; Sznajder, JI | 1 |
| Abel, PW; Bockman, CS; Bruchas, MR; Dowd, FJ; O'Connell, KA; Scofield, MA; Zeng, W | 1 |
| Bendhack, LM; Molin, JC | 1 |
| Mallick, BN; Pal, D; Singh, S | 1 |
| Bakshi, VP; Carasso, BS; Geyer, MA; Palomo, J; Powell, SB | 1 |
| Herndon, JG; Killiany, RJ; Luebke, JI; Moore, TL; Moss, MB; Rosene, DL; Schettler, SP | 1 |
| Ding, X; McCune, DF; Murray, PA; Perez, DM; Sohn, JT | 1 |
| Brock, JA; Yeoh, M | 1 |
| Fülöp, K; Gyires, K; Rónai, AZ; Zádori, Z | 1 |
| Hamm, MW; Levin, BE | 1 |
| Honda, E; Inenaga, K; Kataoka, S; Ono, K | 1 |
| Mallick, BN; Pal, D | 1 |
| Fahim, M; Fazli-Tabaei, S; Khoshbaten, A | 1 |
| Gray, KT; Ventura, S | 1 |
| Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
| Avellar, MC; Caricati-Neto, A; Jurkiewicz, A; Jurkiewicz, NH; Reuter, HR; Verde, LF | 1 |
| Coskun, I; Dogrul, A; Uzbay, T | 1 |
| Feliu-Mojer, M; Jiménez-Rivera, CA; Vázquez-Torres, R | 1 |
| Doze, VA; Hillman, KL; Porter, JE | 1 |
| Chartier, D; Ehrlich, JR; Hébert, TE; Nattel, S; Qi, X; Yeh, YH | 1 |
| Geracioti, TD; Strawn, JR | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Boehnlein, JK; Kinzie, JD | 1 |
| Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Dunkel, P; Fülöp, K; Gyires, K; Shujaa, N; Zádori, ZS | 1 |
| Gyires, K; Kató, E; Lipták, L; Mátyus, P; Rónai, AZ; Shujaa, N | 1 |
| Lu, HG; Ren, LM; Zhang, X; Zhao, D | 1 |
| Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T | 1 |
| Cheevers, CV; Donello, JE; Gil, DW; Kedzie, KM; Manlapaz, CA; Rao, S; Tang, E | 1 |
| Chu, CC; Lin, MT; Shieh, JP; Wang, JJ | 1 |
| Gong, H; Li, Z; Liu, G; Liu, H; Liu, Z; Yang, X | 1 |
| Friedman, GD; Habel, LA; Udaltsova, N | 1 |
| Alexander, JC; Bishnoi, M; Bruijnzeel, AW; Ford, J; Keijzers, KF; Pasek, TM; van Tuijl, IA; Yamada, H; Yavarovich, KR | 1 |
| Auerbach, SH; Aurora, RN; Bista, SR; Casey, KR; Chowdhuri, S; Karippot, A; Kristo, DA; Lamm, CI; Maganti, RK; Morgenthaler, TI; Ramar, K; Zak, RS | 1 |
| Brock, JA; McLachlan, EM; Rummery, NM; Tripovic, D | 1 |
| Briyal, S; Gulati, A; Lavhale, MS; Parikh, N | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Bennett, DJ; D'Amico, J; Gorassini, MA; Murray, KC; Rank, MM; Stephens, MJ | 1 |
| Defino, MC; Hague, C; Olson, VG; Peskind, ER; Raskind, MA; Redila, VA; Reh, RK; Rockett, HR; Szot, P; Tran, PM; Venkov, HA | 1 |
| Armstrong, RB; Behnke, BJ; Delp, MD | 1 |
| Aston-Jones, G; Smith, RJ | 1 |
| Anisman, H | 1 |
| Bockman, CS; Dang, HK; Gruber, DD; Scofield, MA; Wangemann, P; Witt, KM | 1 |
| Alexander, JC; Bishnoi, M; Bruijnzeel, AW; Ford, J; Ji, Y; Rogers, JA; Scheick, S | 1 |
| Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD | 1 |
| Aono, Y; Cools, AR; Koshikawa, N; Saigusa, T; Takada, K; Uchida, T; Verheij, MM | 1 |
| Kelzenberg, B; Lipov, E | 1 |
| Edwards, S; Koob, GF; Park, PE; Schlosburg, JE; Schulteis, G; Vendruscolo, LF | 1 |
| Danyali, F; Ebrahimi-Ghiri, M; Oryan, S; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
| Chies, AB; de Souza Rossignoli, P; Pereira, OC; Yamamoto, FZ | 1 |
| Boughner, E; Cummins Jacklin, E; Kent, K; Kwiatkowski, D; Leri, F; MacDonald, T | 1 |
| Cossío-Bayúgar, R; Fernández-Rubalcaba, M; Miranda-Miranda, E; Narváez Padilla, V; Reynaud, E | 1 |
| Kinzie, JD | 1 |
| Bech, P; Carlsson, J; Mortensen, EL; Sonne, C | 1 |
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| Dantzler, HA; Kline, DD; Milanick, WJ; Polo-Parada, L | 1 |
40 review(s) available for clonidine and prazosin
| Article | Year |
|---|---|
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.
Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses | 1982 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blood Pressure; Clonidine; Diazoxide; Diuretics; Emergencies; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Prazosin; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Trimethaphan | 1977 |
Recent advances in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Drug Therapy, Combination; Humans; Hypertension; Prazosin; Propranolol; Renin; Vasodilator Agents | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Potassium; Prazosin; Secologanin Tryptamine Alkaloids; Sympatholytics | 1977 |
[Etiology, pathogenesis and epidemiology of hypertension].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Benzothiadiazines; Cardiac Output; Clonidine; Diuretics; Drug Evaluation; Haplorhini; Heart Rate; Hemodynamics; Humans; Hypertension; Methyldopa; Middle Aged; Prazosin; Rats; Sodium Chloride; Sodium Chloride Symporter Inhibitors; Stress, Psychological | 1978 |
[New aspects in the treatment of acute cardiac insufficiency].
Topics: Adrenergic beta-Antagonists; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Droperidol; Fentanyl; Fibrinolytic Agents; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Microcirculation; Myocardial Contraction; Neuroleptanalgesia; Nitroprusside; Phentolamine; Prazosin; Respiration, Artificial; Vascular Resistance; Vasodilator Agents | 1978 |
[Cardiac therapy in the old patient].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycosides; Diuretics; Dose-Response Relationship, Drug; Drug Tolerance; Glomerular Filtration Rate; Heart Diseases; Heart Failure; Humans; Hypertension; Isosorbide Dinitrate; Kidney; Methyldopa; Middle Aged; Nitroglycerin; Prazosin; Reserpine; Water-Electrolyte Balance | 1979 |
Preventing, detecting and managing adverse reactions of antihypertensive agents in the ambulant patient with essential hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone | 1977 |
Recent acquisitions in antihypertensive therapy: clonidine, minoxidil and prazosin.
Topics: Animals; Clonidine; Dogs; Hemodynamics; Humans; Hypertension; Minoxidil; Prazosin; Pyrimidines; Quinazolines; Rats | 1978 |
Drug therapy of hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Evaluation; Humans; Hypertension; Prazosin; Propranolol; Sympathetic Nervous System; Vasodilator Agents | 1978 |
Using pharmacokinetics in drug therapy. V: Contributions to developing dosage regimens for antihypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Drug Administration Schedule; Guanethidine; Humans; Hydralazine; Kinetics; Methyldopa; Minoxidil; Prazosin; Propranolol | 1979 |
Comparison of pharmacokinetics and pharmacodynamics of adrenoceptor agonists and antagonists as antihypertensive agents.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Pressure; Clonidine; Doxazosin; Humans; Hypertension; Prazosin | 1987 |
Mono-aminergic receptors and blood pressure.
Topics: Adrenergic beta-Agonists; Blood Pressure; Catechol O-Methyltransferase; Cell Membrane; Clonidine; Dopamine; Epinephrine; Heart Diseases; Humans; Hypertension; Monoamine Oxidase; Muscle, Smooth, Vascular; Neurons; Norepinephrine; Pindolol; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Synapses; Vasoconstriction | 1985 |
Alpha-adrenergic receptors and blood pressure control.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Drug Evaluation; Guanfacine; Guanidines; Half-Life; Heart Rate; Humans; Hypertension; Phenylacetates; Prazosin; Receptors, Adrenergic, alpha | 1986 |
Sexual dysfunction with antihypertensive and antipsychotic agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Antipsychotic Agents; Benzothiadiazines; Calcium Channel Blockers; Clonidine; Diuretics; Ejaculation; Female; Guanethidine; Humans; Male; Methyldopa; Orgasm; Penile Erection; Prazosin; Reserpine; Sexual Dysfunction, Physiological; Sodium Chloride Symporter Inhibitors; Spironolactone | 1986 |
Heterogeneity of alpha-2 adrenergic receptors.
Topics: Animals; Blood Platelets; Brain; Cerebral Cortex; Clonidine; Corpus Striatum; Dogs; Guinea Pigs; Humans; Oxymetazoline; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Species Specificity; Submandibular Gland; Yohimbine | 1985 |
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors.
Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine | 1986 |
Chronic cobalt-induced epilepsy: noradrenaline ionophoresis and adrenoceptor binding studies in the rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Chronic Disease; Clonidine; Cobalt; Dihydroalprenolol; Epilepsy; Iontophoresis; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1985 |
Pharmacology of centrally acting hypotensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methyldopa; Phenylacetates; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1980 |
[Bases of pharmacological therapy of essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Minoxidil; Monoamine Oxidase Inhibitors; Prazosin; Secologanin Tryptamine Alkaloids | 1980 |
Antihypertensive agents 1969-1980.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Ergolines; Fusaric Acid; Guanidines; Humans; Hydralazine; Indoramin; Methyldopa; Minoxidil; Nifedipine; Piperazines; Prazosin; Prostaglandins | 1981 |
Pharmacology and biochemistry of noradrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Dioxins; Idazoxan; Muscle, Smooth, Vascular; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathectomy, Chemical; Vasoconstriction | 1982 |
Central and peripheral blockade of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics | 1984 |
Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Calcium Channel Blockers; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; Ketanserin; Methyldopa; Muscle, Smooth, Vascular; Phenylacetates; Piperazines; Piperidines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Vascular Resistance | 1984 |
Alpha-adrenergic receptor subtypes.
Topics: Animals; Binding, Competitive; Clonidine; Dihydroergotoxine; Epinephrine; Heart Rate; Humans; Hypertension; In Vitro Techniques; Models, Biological; Norepinephrine; Phentolamine; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
The pharmacology of prazosin, a novel antihypertensive agent.
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Brain; Clonidine; Dogs; Heart Rate; Humans; Hypotension, Orthostatic; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Rabbits; Rats; Receptors, Adrenergic, alpha; Renin; Substrate Specificity | 1980 |
Molecular mechanisms involved in alpha-adrenergic responses.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Calcium; Clonidine; Cyclic AMP; Epinephrine; Glucose; Guanosine Triphosphate; Liver; Nordefrin; Phenylephrine; Phosphatidylinositols; Phosphorylase a; Phosphorylase b; Prazosin; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1981 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Phentolamine; Prazosin; Pregnancy; Pulmonary Edema; Trimethaphan | 1984 |
Control of prolactin secretion in mammals.
Topics: Animals; Catecholamines; Clonidine; Dopamine; Endorphins; Mammals; Norepinephrine; Peptides; Prazosin; Prolactin; Secretory Rate; Serotonin; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1980 |
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Infant Mortality; Methyldopa; Nitroprusside; Prazosin; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol; Secologanin Tryptamine Alkaloids; Sodium; Sodium Chloride Symporter Inhibitors | 1980 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Metoprolol; Minoxidil; Nitroprusside; Patient Compliance; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors | 1980 |
Clonidine hydrochloride.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Drug Therapy, Combination; Hemodynamics; Humans; Kinetics; Methyldopa; Prazosin; Propranolol; Renin-Angiotensin System; Vasodilator Agents | 1982 |
Management of systemic hypertension in children.
Topics: Adolescent; Antihypertensive Agents; Child; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Nitroprusside; Prazosin; Propranolol | 1982 |
Distribution and pharmacology of alpha 2-adrenoceptors in the central nervous system.
Topics: Animals; Central Nervous System; Clonidine; Molecular Structure; Prazosin; Receptors, Adrenergic, alpha-2 | 1995 |
Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Clonidine; Humans; Life Change Events; Norepinephrine; Prazosin; Propranolol; Psychopharmacology; Receptors, Adrenergic; Stress Disorders, Post-Traumatic | 2008 |
Sympathetic system modulation to treat post-traumatic stress disorder (PTSD): a review of clinical evidence and neurobiology.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Anti-Anxiety Agents; Autonomic Nerve Block; Clonidine; Cognitive Behavioral Therapy; Humans; Prazosin; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic; Sympathetic Nervous System | 2012 |
Pharmacological treatment of refugees with trauma-related disorders: What do we know today?
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Antidepressive Agents; Antipsychotic Agents; Clonidine; Humans; Practice Guidelines as Topic; Prazosin; Refugees; Stress Disorders, Post-Traumatic | 2017 |
Noradrenergic targets for the treatment of alcohol use disorder.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Adrenergic Neurons; Alcoholism; Clonidine; Drug Delivery Systems; Humans; Norepinephrine; Prazosin; Propranolol; Receptors, Adrenergic | 2018 |
17 trial(s) available for clonidine and prazosin
| Article | Year |
|---|---|
Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine.
Topics: Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Time Factors | 1977 |
Prazosin and clonidine for moderately severe hypertension.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Polythiazide; Prazosin; Quinazolines | 1978 |
Antihypertensive effect of prazosin in combination with methyldopa, clonidine, or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Combinations; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Prazosin; Propranolol; Quinazolines | 1979 |
[Multicomponent therapy of severe arterial hypertension in a hospital].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hospitalization; Humans; Hypertension, Malignant; Male; Middle Aged; Pindolol; Prazosin | 1991 |
Sensitization of human alpha 1- and alpha 2-adrenergic venous responses by guanadrel sulfate.
Topics: Adolescent; Adult; Clonidine; Dose-Response Relationship, Drug; Guanidines; Hand; Humans; Male; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Vasoconstriction | 1990 |
Hemodynamic responses to different levels of alpha-adrenergic interruption in congestive heart failure.
Topics: Adrenergic alpha-Antagonists; Clonidine; Extremities; Female; Heart Failure; Hemodynamics; Humans; Indoramin; Liver; Liver Circulation; Male; Middle Aged; Prazosin; Regional Blood Flow; Stroke Volume; Vascular Resistance; Ventricular Function, Left | 1988 |
Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.
Topics: Adult; Atenolol; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Physical Exertion; Prazosin | 1985 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol | 1980 |
Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Random Allocation; Renin-Angiotensin System; Time Factors | 1984 |
[Changes in vigilance after acute and repeated administration of the antihypertensive agents clonidine and prazosin].
Topics: Adult; Attention; Clonidine; Female; Humans; Hypertension; Long-Term Care; Male; Prazosin; Quinazolines; Saccades | 1983 |
Diuretic therapy for mild hypertension: the "real" cost of treatment.
Topics: Aged; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Cost-Benefit Analysis; Diet; Diuretics; Humans; Hypertension; Life Style; Middle Aged; Physical Exertion; Prazosin; Prospective Studies; Sodium Chloride Symporter Inhibitors; Water-Electrolyte Imbalance | 1984 |
A comparison of the hemodynamic effects of urapidil, prazosin, and clonidine in healthy volunteers.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Administration Schedule; Heart Rate; Humans; Male; Norepinephrine; Piperazines; Prazosin; Vascular Resistance | 1994 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin | 1993 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs | 1997 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States | 1999 |
Alpha 2-agonist versus alpha 1-antagonist in mild-to-moderate hypertension: comparison of transdermal clonidine and terazosin monotherapies.
Topics: Administration, Cutaneous; Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin | 1997 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome | 2001 |
798 other study(ies) available for clonidine and prazosin
| Article | Year |
|---|---|
Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Heterocyclic Compounds; Male; Rats; Vas Deferens | 1989 |
Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Imidazoles; Indoles; Male; Mice; Nociceptors; Pain; Prazosin; Quinolines; Rats; Structure-Activity Relationship; Vas Deferens | 1987 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
1-(alkylamino)isochromans: hypotensives with peripheral and central activities.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Brain; Cats; Chromans; Female; Heart Rate; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Sympathetic Nervous System | 1982 |
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens | 1983 |
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction | 1984 |
Antihypertensive pyrrolo[1,2-c]quinazolines and pyrrolo[1,2-c]quinazolinones.
Topics: Animals; Antihypertensive Agents; Male; Quinazolines; Rats; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Hypotension; Male; Molecular Structure; Piperazines; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship | 2015 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Minoxidil; Nitroprusside; Prazosin; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympatholytics; Triamterene; Trimethaphan; Vasodilator Agents | 1977 |
Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Synapses; Vas Deferens; Yohimbine | 1977 |
Long-term use of prazosin in combination or alone for treating hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines | 1977 |
Prazosin: differential affinities for two populations of alpha-noradrenergic receptor binding sites.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dihydroergotoxine; In Vitro Techniques; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
The interaction between prazosin and clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Heart Rate; Prazosin; Quinazolines; Rats | 1978 |
[Treatment of arterial hypertension in the aged].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Hypertension, Renovascular; Methyldopa; Prazosin; Prostaglandins, Synthetic; Reserpine | 1978 |
Approach to drug therapy for hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Guanidines; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Patient Care Planning; Patient Compliance; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Vasodilator Agents | 1979 |
Prazosin and phentolamine: comparative cardiovascular and autonomic profiles.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Female; Guinea Pigs; Heart; In Vitro Techniques; Leg; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Sympathetic Nervous System; Vasodilator Agents | 1978 |
Alpha adrenoceptors in rat brain: direct identification with prazosin.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Clonidine; Hydrogen-Ion Concentration; In Vitro Techniques; Membranes; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Time Factors | 1979 |
[Hypotensive drugs].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Guanidines; Humans; Hypertension; Methyldopa; Minoxidil; Prazosin; Secologanin Tryptamine Alkaloids; Vasodilator Agents | 1979 |
[The practitioner and drug-induced, predominantly orthostatic hypotension].
Topics: Adrenergic Agents; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Antipsychotic Agents; Barbiturates; Butyrophenones; Clonidine; Debrisoquin; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypotension, Orthostatic; Levodopa; Meprobamate; Methyldopa; Mineralocorticoids; Monoamine Oxidase Inhibitors; Phenothiazines; Prazosin; Psychotropic Drugs; Reserpine; Vasodilator Agents | 1978 |
Differential effects of prazosin on the pre- and postsynaptic alpha-adrenoceptors in the rat and dog [proceedings].
Topics: Animals; Clonidine; Dogs; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Species Specificity | 1977 |
Direct biochemical demonstration of two types of alpha-adrenoreceptor in rat brain.
Topics: Animals; Binding, Competitive; Brain; Clonidine; Dihydroergotoxine; Dopamine; Male; Phenoxybenzamine; Phentolamine; Piperoxan; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine | 1978 |
Prazosin and presynaptic alpha-receptors in the cardioaccelerator nerve of the dog.
Topics: Animals; Clonidine; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Male; Myocardial Contraction; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vagotomy; Yohimbine | 1978 |
The interaction between prazosin and clonidine at alpha-adrenoceptors in rats and cats.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Clonidine; Drug Interactions; Female; Hemodynamics; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord | 1979 |
Effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat.
Topics: Animals; Cats; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Female; Heart Rate; Imidazoles; Male; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
Propranolol and newer antihypertensive drugs in the management of hypertension.
Topics: Angiotensin II; Clonidine; Diuretics; Humans; Hypertension; Minoxidil; Prazosin; Propranolol; Saralasin; Vasodilator Agents | 1979 |
Studies on the inhibitory action of somatostatin in the electrically stimulated rat vas deferens.
Topics: Animals; Calcium; Clonidine; Electric Stimulation; Endorphins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Somatostatin; Vas Deferens | 1979 |
Effect of clonidine on utilization and potassium-evoked release of adrenaline in rat brain areas.
Topics: Animals; Brain; Clonidine; Epinephrine; Hypothalamus; Male; Organ Specificity; Potassium; Prazosin; Rats; Yohimbine | 1979 |
Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs.
Topics: Animals; Catecholamines; Clonidine; Coronary Vessels; Dogs; Drug Interactions; Electric Stimulation; Female; Heart; Heart Rate; Male; Phentolamine; Prazosin; Quinazolines; Spinal Cord; Time Factors | 1979 |
Anticonvulsant effect of yohimbine in quaking mice: antagonism by clonidine and prazosine.
Topics: Animals; Anticonvulsants; Clonidine; Male; Mice; Mice, Quaking; Phentolamine; Prazosin; Quinazolines; Seizures; Yohimbine | 1979 |
Modification by antihypertensive drugs of amphetamine-induced stereotypy in rats.
Topics: Animals; Antihypertensive Agents; Behavior; Clonidine; Dextroamphetamine; Drug Interactions; Humans; Male; Mianserin; Prazosin; Rats; Stereotyped Behavior; Yohimbine | 1979 |
The effects of prazosin on the clonidine induced hypotension and bradycardia in rats and sedation in chicks [proceedings].
Topics: Animals; Blood Pressure; Chickens; Clonidine; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Prazosin; Quinazolines; Rats | 1978 |
Workup and treatment of the average hypertensive patient.
Topics: Benzothiadiazines; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Prazosin; Propranolol; Radiography; Renin; Reserpine; Sodium Chloride Symporter Inhibitors | 1978 |
Treatment of chronic essential hypertension.
Topics: Chlorothiazide; Clonidine; Diabetes Mellitus; Diet, Sodium-Restricted; Gout; Guanethidine; Humans; Hydralazine; Hypertension; Hypnotics and Sedatives; Medical History Taking; Methyldopa; Patient Compliance; Physical Examination; Phytotherapy; Plants, Medicinal; Potassium; Prazosin; Prognosis; Propranolol; Rauwolfia; Sympathectomy; Tranquilizing Agents | 1977 |
Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon.
Topics: Adenylate Cyclase Toxin; Animals; Binding, Competitive; Cell Membrane; Clonidine; Colforsin; Colon; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 1992 |
Separation of putative alpha 1A- and alpha 1B-adrenoceptor mediated components in the tension response of the rat vas deferens to electrical field stimulation.
Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Suramin; Vas Deferens | 1992 |
Functional characterization of alpha-adrenoceptors on pancreatic islets of fa/fa Zucker rats.
Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Glucose; Insulin; Islets of Langerhans; Obesity; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Effects of estrogen pretreatment of the spare alpha 1-adrenoceptors and the slow and fast components of the contractile response of the isolated female rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Estrogens; Female; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
The contribution of alpha-adrenoceptors to neurally-mediated contractions of the rabbit urethral smooth muscle.
Topics: Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Urethra; Yohimbine | 1992 |
Estradiol selectively regulates alpha 1B-noradrenergic receptors in the hypothalamus and preoptic area.
Topics: Animals; Clonidine; Cyclic AMP; Dioxanes; Estradiol; Female; Hypothalamus; Ovariectomy; Piperazines; Prazosin; Preoptic Area; Rats; Receptors, Adrenergic | 1992 |
Intrathecal St-587: effects on nociceptive reflexes and blood pressure in the rat.
Topics: Animals; Blood Pressure; Clonidine; Guanfacine; Hot Temperature; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Nociceptors; Prazosin; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Urethane | 1992 |
Central alpha 2-adrenoceptor-mediated pressor response to clonidine in conscious, spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Furosemide; Heart Rate; Hypertension; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Water Deprivation; Yohimbine | 1992 |
Different types of norepinephrinergic receptors are involved in preoptic area mediated independent modulation of sleep-wakefulness and body temperature.
Topics: Acetamides; Animals; Body Temperature Regulation; Clonidine; Isoproterenol; Male; Methoxamine; Prazosin; Preoptic Area; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic; Sleep; Sodium Chloride; Wakefulness; Yohimbine | 1992 |
Characterization of alpha 1-adrenoceptor subtypes labeled by [3H]prazosin in single cells prepared from rabbit thoracic aorta.
Topics: Animals; Aorta, Thoracic; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Methoxamine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spiperone | 1992 |
[Alpha adrenoceptor subtypes in smooth muscles of rat pulmonary artery].
Topics: Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1992 |
Subtype-selective alpha-1 adrenoceptor alkylation in the rat kidney and its effect on the vascular pressor response.
Topics: Adrenergic alpha-Antagonists; Alkylation; Animals; Clonidine; Imidazoles; Kidney; Male; Methoxamine; Phenylephrine; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Artery | 1992 |
Release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.
Topics: Animals; Butoxamine; Calcium; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Ganglionic Blockers; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Metoprolol; Norepinephrine; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Splanchnic Nerves; Stomach; Tetrodotoxin; Yohimbine | 1992 |
Suppression by spinal alpha-2 agonists of motor and autonomic responses evoked by low- and high-intensity thermal stimuli.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hot Temperature; Imidazoles; Male; Medetomidine; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic, alpha; Reflex | 1992 |
[Ocular hypotensive effect of alpha-adrenoceptor agonist and antagonist in the conscious pigmented rabbit].
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Ventricles; Clonidine; Depression, Chemical; Eye Color; Intraocular Pressure; Male; Prazosin; Rabbits | 1992 |
Alpha-adrenergic input in the locus coeruleus modulates plasma adrenocorticotropin in cats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Cats; Clonidine; Female; Glutamates; Glutamic Acid; Kinetics; Locus Coeruleus; Male; Microinjections; Phenylephrine; Pons; Prazosin; Radioimmunoassay; Receptors, Adrenergic, alpha; Reference Values; Time Factors; Yohimbine | 1992 |
Cardiovascular responses of sinoaortic-denervated rats to intracerebroventricular injection of alpha 1- and alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Denervation; Dioxanes; Heart Rate; Idazoxan; Injections, Intraventricular; Phenylephrine; Prazosin; Pressoreceptors; Rats; Rats, Inbred Strains | 1992 |
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Blood Glucose; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Idazoxan; Imidazoles; Insulin; Male; Muscles; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1992 |
Participation of arginine vasopressin-mediated and adrenergic system-mediated mechanisms in the hypertension induced by intracerebroventricular administration of NMDA in freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; N-Methylaspartate; Naloxone; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains | 1992 |
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Doxazosin; Drug Implants; Eating; Food; Male; Morphine; Morphine Dependence; Motor Activity; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Effect of chlorethylclonidine on arterial blood pressure and heart rate in the conscious rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Clonidine; Heart Rate; Injections, Intraperitoneal; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
Evidence for a noradrenergic innervation to alpha 1A-adrenoceptors in rat kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium Channels; Clonidine; In Vitro Techniques; Kidney; Male; Nitrendipine; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction | 1992 |
The effects of electroconvulsive shock or imipramine on subtypes of alpha 1-adrenoceptors in the frontal cortex of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Clonidine; Dioxanes; Electroshock; Hippocampus; Imipramine; In Vitro Techniques; Kinetics; Male; Prazosin; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1992 |
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation?
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine | 1992 |
Identification of alpha 1-adrenoceptor subtypes in the rat vas deferens: binding and functional studies.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Electric Stimulation; Epididymis; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Nifedipine; Norepinephrine; Oxathiins; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vas Deferens | 1992 |
Pharmacological characterization of contractile responses induced by alpha 1-agonists, norepinephrine and clonidine, by selective antagonists of their subtypes in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rabbits | 1992 |
[Effects of four adrenergic drugs on electroacupuncture analgesia].
Topics: Acupuncture Analgesia; Adrenergic alpha-Agonists; Animals; Clonidine; Electroacupuncture; Female; Methoxamine; Pain Threshold; Prazosin; Rats; Yohimbine | 1992 |
Development of a new rabbit ear model for the longitudinal study of digital pathophysiology.
Topics: Albuterol; Animals; Aorta, Abdominal; Blood Pressure; Catheterization, Peripheral; Clonidine; Disease Models, Animal; Ear, External; Fingers; Laser-Doppler Flowmetry; Male; Microcirculation; Phenylephrine; Prazosin; Pulsatile Flow; Rabbits; Regional Blood Flow; Rheology; Skin | 1992 |
Atypical presynaptic alpha-adrenoceptor modulation of neurally-mediated cholinergic responses in guinea-pig tracheal smooth muscle.
Topics: Animals; Clonidine; Drug Interactions; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Trachea; Yohimbine | 1992 |
Disturbance or relatively important actions of antihypertensives, antifungal agent and opiate antagonist to the testicular steroidogenesis in rat.
Topics: Androstenedione; Animals; Antifungal Agents; Antihypertensive Agents; Clonidine; Estradiol; Ketoconazole; Male; Naloxone; Narcotic Antagonists; Prazosin; Rats; Testis; Testosterone; Verapamil | 1992 |
Production and characterization of an iminoimidazolidine specific monoclonal antibody using para-aminoclonidine as antigen.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Antigens; Binding, Competitive; Brain; Clonidine; Female; Glutaral; Hemocyanins; Humans; Imidazoles; Kinetics; Mice; Mice, Inbred BALB C; Prazosin; Tissue Extracts; Vaccines, Synthetic; Yohimbine | 1992 |
[Inhibitory effect of clonidine on hemolysis after thermal injury in animals].
Topics: Animals; Burns; Clonidine; Glutathione; Glutathione Peroxidase; Hemolysis; Male; Mice; Norepinephrine; Osmotic Fragility; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1992 |
Alpha 1- and alpha 2-adrenergic response in human isolated skin arteries during cooling.
Topics: Adult; Aged; Arteries; Clonidine; Cold Temperature; Drug Interactions; Humans; In Vitro Techniques; Isometric Contraction; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Phenylephrine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Regional Blood Flow; Skin; Yohimbine | 1991 |
Alpha 1-adrenergic receptor coupling with phospholipase-C is negatively regulated by protein kinase-C in primary cultures of hypothalamic neurons and glial cells.
Topics: Animals; Astrocytes; Calcium Channels; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Clonidine; Diglycerides; Feedback; GTP-Binding Proteins; Hypothalamus; Inositol Phosphates; Kinetics; Membrane Lipids; Mice; Neurons; Norepinephrine; Phenoxybenzamine; Phosphatidylinositols; Prazosin; Propranolol; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Type C Phospholipases; Yohimbine | 1991 |
The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (-)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Ganglia, Sympathetic; Heart Rate; Kidney; Maprotiline; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Stereoisomerism; Sympathetic Nervous System; Yohimbine | 1991 |
Role of alpha-adrenoceptors in control of plasma potassium in conscious rabbits.
Topics: Animals; Apamin; Calcium Channels; Clonidine; Dioxanes; Ethanolamines; Hyperkalemia; Idazoxan; Potassium; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Verapamil | 1991 |
Thymus-induced recovery of age-related decrease of brain cortex alpha- and beta-adrenoceptors.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cerebral Cortex; Clonidine; Dihydroalprenolol; In Vitro Techniques; Kinetics; Membranes; Mice; Mice, Inbred BALB C; Practolol; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Thymus Gland | 1991 |
Changes in plasma glucose and lactate evoked by alpha and beta 2-adrenoceptor stimulation in conscious fasted rabbits.
Topics: Albuterol; Analysis of Variance; Animals; Blood Glucose; Clonidine; Dioxanes; Epinephrine; Fasting; Idazoxan; Lactates; Male; Picolinic Acids; Prazosin; Propanolamines; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Spectrophotometry | 1991 |
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine | 1991 |
Relation between adrenergic neurogenic contraction and alpha 1-adrenoceptor subtypes in dog mesenteric and carotid arteries and rabbit carotid arteries.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Clonidine; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1991 |
Comparative study of postsynaptic alpha-adrenoceptors in aorta obtained from human and other mammalian species.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Clonidine; Guinea Pigs; Humans; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1991 |
Clonidine causes antidepressant-like effects in rats by activating alpha 2-adrenoceptors outside the locus coeruleus.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Clonidine; Desipramine; Dioxanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxydopamines; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Interaction of imidazolines with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Drug Interactions; Imidazoles; Injections, Intraperitoneal; Male; Muscle, Smooth, Vascular; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Regional distribution of alpha 1-adrenoceptor subtypes in rat kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Cell Membrane; Clonidine; Dioxanes; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Alpha 1-adrenoceptor subtypes in aorta (alpha 1A) and liver (alpha 1B).
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Liver; Membranes; Muscle, Smooth, Vascular; Phosphatidylinositols; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1991 |
Pharmacological profile of the novel alpha-adrenoceptor antagonist KT-611 (naftopidil).
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dogs; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Piperazines; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1991 |
Iontophoretic analysis of the pharmacologic mechanisms responsible for initiation and modulation of trigeminal motoneuronal discharge evoked by intra-oral afferent stimulation.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Clonidine; Dental Pulp; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Motor Neurons; Mouth Mucosa; Neck Muscles; Nerve Fibers; Norepinephrine; Phenylephrine; Prazosin; Synapses; Synaptic Transmission; Tongue; Trigeminal Nerve; Yohimbine | 1991 |
Adrenoceptors of the human internal thoracic artery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Clonidine; Dinoprostone; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic; Serotonin; Thoracic Arteries; Yohimbine | 1991 |
Evidence for a complex interaction between the subtypes of the alpha 1-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Kinetics; Male; Methoxamine; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Influence of fenoldopam and quinpirole in the guinea-pig stomach.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clonidine; Dopamine; Dopamine Agents; Electric Stimulation; Ergolines; Female; Fenoldopam; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Methysergide; Muscle Contraction; Muscle Relaxation; Prazosin; Quinpirole; Stomach; Yohimbine | 1991 |
MCI-9042: high affinity for serotonergic receptors as assessed by radioligand binding assay.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Clonidine; Hippocampus; In Vitro Techniques; Ketanserin; Kinetics; Platelet Aggregation Inhibitors; Prazosin; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Serotonin; Succinates | 1991 |
Potent inhibitory action of chlorethylclonidine on the positive inotropic effect and phosphoinositide hydrolysis mediated via myocardial alpha 1-adrenoceptors in the rabbit ventricular myocardium.
Topics: Adrenergic alpha-Antagonists; Animals; Bupranolol; Clonidine; Drug Interactions; Epinephrine; Heart Ventricles; Inositol Phosphates; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylephrine; Phosphatidylinositols; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1991 |
Effects of selective adrenergic agonists and antagonists on gastric tone in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Clonidine; Dose-Response Relationship, Drug; Phenylephrine; Prazosin; Prenalterol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stomach; Yohimbine | 1991 |
Alpha-2 adrenoreceptors mediate clonidine-induced hypoinsulinaemia in sheep.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Clonidine; Dioxanes; Eating; Female; Idazoxan; Injections, Intravenous; Insulin; Male; Prazosin; Receptors, Adrenergic, alpha; Sheep | 1991 |
Human plasma-derived material with clonidine displacing substance (CDS)-like properties contracts the isolated rat aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood; Brain; Clonidine; Dioxanes; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Prazosin; Rats; Rats, Inbred WKY; Yohimbine | 1991 |
Behavioral models in mice. Implication of the alpha noradrenergic system.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Depression; Dioxanes; Hydroxamic Acids; Idazoxan; Male; Mice; Motor Activity; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Swimming | 1991 |
Effects of alpha-noradrenergic substances on the optokinetic and vestibulo-ocular responses in the rabbit: a study with systemic and intrafloccular injections.
Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebellum; Clonidine; Dioxanes; Eye Movements; Female; Idazoxan; Injections, Intravenous; Male; Microinjections; Phenylephrine; Prazosin; Rabbits; Reflex, Vestibulo-Ocular | 1991 |
The alkylating prazosin analog SZL 49 inactivates both alpha 1A- and alpha 1B-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Drug Synergism; Hippocampus; Liver; Male; Membranes; Phenethylamines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones | 1991 |
Three distinct binding sites for [3H]-prazosin in the rat cerebral cortex.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Clonidine; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Higher alpha-noradrenergic receptors in paraventricular nucleus of obese Zucker rats: decline after food deprivation.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Food Deprivation; Norepinephrine; Obesity; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha | 1991 |
Enhanced contractile responses of arteries from diabetic rats to alpha 1-adrenoceptor stimulation in the absence and presence of extracellular calcium.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arteries; Calcium; Clonidine; Diabetes Mellitus, Experimental; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
First-choice antihypertensive drug use in the Glasgow Blood Pressure Clinic.
Topics: Adrenergic beta-Antagonists; Ambulatory Care Facilities; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Costs and Cost Analysis; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin; Scotland | 1990 |
Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Heart Rate; Hydralazine; Hypertension; Male; Metoprolol; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Inhibitory effects of clonidine and tizanidine on release of substance P from slices of rat spinal cord and antagonism by alpha-adrenergic receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Parasympatholytics; Piperoxan; Prazosin; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Veratridine; Yohimbine | 1991 |
Clonidine differentially modulates the release of endogenous GABA in various rat brain areas.
Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; In Vitro Techniques; Male; Medulla Oblongata; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1991 |
Naloxone-induced hypoalgesia: effects of noradrenergic antagonists and agonist.
Topics: Animals; Clonidine; Hot Temperature; Male; Naloxone; Norepinephrine; Pain; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds; Yohimbine | 1991 |
Renal alpha 1-adrenergic receptor subtypes: MDCK-D1 cells, but not rat cortical membranes possess a single population of receptors.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Cell Membrane; Clonidine; Dogs; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Phosphatidylcholines; Phosphatidylinositols; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Tissue Distribution | 1991 |
The mechanism of the sympathoinhibitory action of urapidil: role of 5-HT1A receptors.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Clonidine; Heart; Heart Rate; Kidney; Male; Piperazines; Prazosin; Receptors, Serotonin; Regional Blood Flow; Spiperone; Splanchnic Nerves; Sympatholytics | 1991 |
[Brain adrenoreceptors in rats with inherited arterial hypertension due to emotional stress].
Topics: Animals; Brain; Clonidine; Dihydroalprenolol; Hypertension; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Species Specificity; Stress, Psychological | 1991 |
Desipramine enhances isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; Clonidine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Prazosin; Social Isolation; Yohimbine | 1991 |
Physiological role of alpha-adrenoceptors in salivary secretion.
Topics: Animals; Autonomic Nervous System; Clonidine; Dose-Response Relationship, Drug; Female; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Submandibular Gland; Yohimbine | 1990 |
Effects of dilevalol on adrenoceptors in isolated cat arteries.
Topics: Animals; Arteries; Cats; Clonidine; Dinoprost; Electric Stimulation; Female; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction; Yohimbine | 1990 |
Concomitant depression of locus coeruleus neurons and of flexor reflexes by an alpha 2-adrenergic agonist in rats: a possible mechanism for an alpha 2-mediated muscle relaxation.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Locus Coeruleus; Male; Muscle Contraction; Muscle Relaxation; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Dietary sodium restriction and blood pressure response to sympathetic blockade in young versus adolescent spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Body Weight; Clonidine; Diet, Sodium-Restricted; Heart Rate; Hexamethonium Compounds; Male; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sympatholytics | 1990 |
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Blood Vessels; Clonidine; Dioxanes; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1990 |
Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Idazoxan; Male; Pain; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Effects of neurotropic agents with a selectivity for alpha-adrenoceptors on nitrile-induced dyskinetic syndrome in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dyskinesia, Drug-Induced; Male; Mice; Nitriles; Phenylephrine; Prazosin; Yohimbine | 1990 |
Pharmacological characterization of the postjunctional alpha-adrenoceptors of the rat isolated seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Naphazoline; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seminal Vesicles; Yohimbine | 1990 |
Napamezole, an alpha-2 adrenergic receptor antagonist and monoamine uptake inhibitor in vitro.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Brain; Cells, Cultured; Clonidine; Dioxanes; Idazoxan; Imidazoles; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Prazosin; Rats; Receptors, Adrenergic, alpha; Synaptosomes; Vas Deferens | 1990 |
Agonist interaction with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Diltiazem; Dioxanes; Drug Interactions; Heart; Inositol Phosphates; Male; Muscle, Smooth, Vascular; Myocardium; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
[The identification and characteristics of subpopulations of alpha 1-adrenergic receptors].
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Calcium; Clonidine; Dioxanes; GTP-Binding Proteins; Liver; Microsomes; Phentolamine; Prazosin; Rats; Receptors, Adrenergic, alpha | 1990 |
[Implication of alpha-2 adrenergic post-synaptic receptors in the central catecholaminergic stimulation of the corticotropic axis in rats].
Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Clonidine; Depression, Chemical; Dioxanes; Drug Therapy, Combination; Female; Idazoxan; Injections, Intraventricular; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1990 |
Inhibitory effects of catecholamines in the paravertebral sympathetic ganglia of the anesthetized dog.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Catecholamines; Clonidine; Dogs; Ganglia, Sympathetic; Hexamethonium Compounds; Male; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Regional Blood Flow; Vascular Resistance; Yohimbine | 1990 |
Effects of alpha-adrenergic agents on generation of oscillatory afterpotentials and triggered activity in rabbit Purkinje fibers.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Male; Membrane Potentials; Phenylephrine; Potassium; Prazosin; Propranolol; Purkinje Fibers; Rabbits; Receptors, Adrenergic, alpha; Strophanthidin; Yohimbine | 1990 |
Alpha-1 adrenergic receptor binding and adrenergic-stimulated cyclic AMP production in rat cerebral cortex after chronic lithium treatment.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Chlorides; Clonidine; Cyclic AMP; Lithium; Lithium Chloride; Male; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Second Messenger Systems | 1990 |
Two distinct alpha 1-adrenoceptor subtypes involved in noradrenaline contraction of the rabbit thoracic aorta.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Female; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 1990 |
Isolated bovine cerebral arteries from rostral and caudal regions: distinct responses to adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Basilar Artery; Carotid Arteries; Cattle; Cerebral Arteries; Clonidine; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Yohimbine | 1990 |
Modulation of 5-hydroxytryptamine release by presynaptic inhibitory alpha 2-adrenoceptors in the human cerebral cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Animals; Cerebral Cortex; Clonidine; Dioxanes; Female; Guinea Pigs; Humans; Idazoxan; In Vitro Techniques; Male; Methoxamine; Middle Aged; Prazosin; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1990 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Practolol; Prazosin; Yohimbine | 1991 |
Effect of adrenergic agonists on glycogenolysis in primary cultures of astrocytes.
Topics: Alprenolol; Animals; Astrocytes; Cells, Cultured; Clonidine; Glycogen; Isoproterenol; Mice; Norepinephrine; Potassium; Prazosin; Yohimbine | 1990 |
Prejunctional alpha 1-adrenoceptors modify release of [3H]noradrenaline in the guinea-pig vas deferens.
Topics: Animals; Clonidine; Cocaine; Desoxycorticosterone; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1990 |
Characterization of alpha 1-adrenergic receptor subtypes linked to iodide efflux in rat FRTL cells.
Topics: Animals; Calcium; Cells, Cultured; Clonidine; Dose-Response Relationship, Drug; Iodides; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Thyroid Gland; Time Factors | 1990 |
Obesity-prone and -resistant rats differ in their brain [3H]paraminoclonidine binding.
Topics: Animals; Brain; Clonidine; Male; Obesity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Down-regulation of alpha 2-adrenoceptors involved in growth hormone control in the hypothalamus of infant rats receiving short-term clonidine administration.
Topics: Animals; Clonidine; Growth Hormone; Hypothalamus; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
The role of alpha 1-adrenoceptor subtypes in the regulation of arterial blood pressure.
Topics: Anesthesia; Animals; Aorta, Thoracic; Binding Sites; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Presynaptic alpha adrenoceptor modulation of neurally mediated cholinergic excitatory and nonadrenergic noncholinergic inhibitory responses in guinea pig trachea.
Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Male; Parasympathetic Nervous System; Prazosin; Receptors, Adrenergic, alpha; Trachea; Yohimbine | 1990 |
Role of alpha adrenoceptors in opossum internal anal sphincter.
Topics: Anal Canal; Animals; Clonidine; Muscle Contraction; Naphazoline; Opossums; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Pertussis toxin inhibits norepinephrine-stimulated inositol phosphate formation in primary brain cell cultures.
Topics: Animals; Brain; Calcium; Carbachol; Cells, Cultured; Clonidine; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Inositol Phosphates; Norepinephrine; Pertussis Toxin; Phenethylamines; Prazosin; Rats; Receptors, Adrenergic, alpha; Tetralones; Virulence Factors, Bordetella; Yohimbine | 1990 |
Role of central alpha 1- and alpha 2-adrenoceptors on the dipsogenic and cardiovascular effect of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Central Nervous System; Clonidine; Drinking Behavior; Heart Rate; Hemodynamics; Injections, Intraventricular; Male; Prazosin; Rats; Receptors, Adrenergic, alpha; Stereotaxic Techniques | 1990 |
Alpha-adrenergic regulation of secretion by tracheal glands.
Topics: Animals; Cats; Clonidine; Dihydroergotoxine; Epinephrine; Female; Glycoconjugates; Isoproterenol; Kinetics; Male; Organ Culture Techniques; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Trachea; Yohimbine | 1990 |
Alpha 2-adrenoceptors in homogenates of rat nasal mucosa.
Topics: Animals; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Nasal Mucosa; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Yohimbine | 1990 |
Reserpine induces vascular alpha 2-adrenergic supersensitivity and platelet alpha 2-adrenoceptor up-regulation in dog.
Topics: Adipose Tissue; Animals; Blood Platelets; Blood Pressure; Cardiovascular System; Catecholamines; Cell Membrane; Clonidine; Dioxanes; Dogs; Heart Rate; Idazoxan; Male; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Up-Regulation; Yohimbine | 1990 |
Spinal alpha 1- and alpha 2-adrenoceptors mediate facilitation and inhibition of spinal motor transmission, respectively.
Topics: Animals; Clonidine; Clorgyline; Levodopa; Male; Motor Neurons; Piperoxan; Prazosin; Premedication; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission | 1990 |
Clonidine and phenylephrine injected into the lateral hypothalamus inhibits water intake in rats.
Topics: Angiotensin II; Animals; Clonidine; Dehydration; Drinking; Eating; Hypothalamic Area, Lateral; In Vitro Techniques; Injections; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Rats; Yohimbine | 1990 |
The involvement of central noradrenergic systems and corticotropin-releasing factor in defensive-withdrawal behavior in rats.
Topics: Animals; Behavior, Animal; Cerebrospinal Fluid; Chlordiazepoxide; Clonidine; Corticotropin-Releasing Hormone; Humans; Injections, Intraperitoneal; Injections, Intravenous; Male; Neurons; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Recombinant Proteins | 1990 |
[Effects of clonidine and norepinephrine on rabbit pulmonary artery strips with or without endothelium].
Topics: Animals; Clonidine; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propranolol; Pulmonary Artery; Rabbits; Yohimbine | 1990 |
Noradrenergic modulation of the masseteric reflex in behaving cats. I. Pharmacological studies.
Topics: Animals; Behavior, Animal; Cats; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Injections; Masseter Muscle; Masticatory Muscles; Methysergide; Norepinephrine; Phenylephrine; Prazosin; Reflex; Time Factors; Trigeminal Nuclei | 1990 |
An EEG and behavioural study on the interactions of clonidine with phencyclidine and ketamine in rats.
Topics: Animals; Brain; Clonidine; Drug Interactions; Electroencephalography; Ketamine; Male; Muscle Tonus; Phencyclidine; Prazosin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1990 |
DSP-4-induced depletion of brain norepinephrine produces opposite effects on exploratory behavior 3 and 14 days after treatment.
Topics: Animals; Benzylamines; Brain Chemistry; Cerebral Cortex; Clonidine; Dioxanes; Exploratory Behavior; Hippocampus; Idazoxan; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Phenylephrine; Prazosin; Restraint, Physical; Sympathomimetics | 1990 |
Noradrenergic mechanisms in the central amygdalar nucleus and gastric stress ulcer formation in rats.
Topics: Adrenergic Fibers; Amygdala; Animals; Clonidine; Male; Microinjections; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 1990 |
Chloroethylclonidine unmasks a non-alpha-adrenoceptor noradrenaline binding site in the rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic; Yohimbine | 1990 |
Effects of systemic and intracerebroventricular phenylephrine and clonidine on corticosterone secretion in rats.
Topics: Animals; Clonidine; Corticosterone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Characterization of adrenoceptor subtypes in cat cutaneous vasculature.
Topics: Animals; Azepines; Cats; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Male; Norepinephrine; Prazosin; Receptors, Adrenergic; Regional Blood Flow; Skin; Vasoconstriction | 1990 |
Decreased gastric acid output following neuropeptide Y administration into the lateral cerebral ventricle of conscious rats.
Topics: Animals; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Gastric Acid; Injections, Intraventricular; Neuropeptide Y; Prazosin; Rats; Rats, Inbred Strains | 1990 |
The effects of phosphatidylserine on the decreased cardiovascular response to clonidine microinfused into the nucleus tractus solitarii of old rats.
Topics: Aging; Animals; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Infusions, Intravenous; Male; Medulla Oblongata; Methoxamine; Phentolamine; Phosphatidylserines; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Mechanism of the hypotensive effect of a new beta-adrenergic blocking drug, arotinolol (S-596) in anesthetized rabbits.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Isoproterenol; Kidney; Male; Phenylephrine; Prazosin; Propanolamines; Propranolol; Rabbits | 1985 |
Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Labetalol; Male; Phenylephrine; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Vasodilation; Yohimbine | 1985 |
Alpha 2 adrenergic receptors in hyperplastic human prostate: identification and characterization using [3H] rauwolscine.
Topics: Binding, Competitive; Cerebral Cortex; Clonidine; DNA; Humans; Kinetics; Male; Nordefrin; Prazosin; Prostate; Prostatic Hyperplasia; Radioligand Assay; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1986 |
Pharmacological characterization of the receptor mediating the adrenergic inhibition of responses to substance P in the cingulate cortex.
Topics: Albuterol; Animals; Clonidine; Dopamine; Epinephrine; Gyrus Cinguli; Male; Norepinephrine; Phentolamine; Phenylephrine; Practolol; Prazosin; Rats; Receptors, Adrenergic, beta; Substance P | 1986 |
Influence of the alpha-2 agonist oxaminozoline (S3341) on firing rate of central noradrenergic and serotonergic neurons in the rat. Comparison with clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Electrophysiology; Iontophoresis; Locus Coeruleus; Male; Neurons; Norepinephrine; Oxazoles; Prazosin; Raphe Nuclei; Rats; Rilmenidine; Serotonin; Yohimbine | 1986 |
Modulation of norepinephrine release through alpha 1- and alpha 2-adrenoceptors in rat isolated kidney.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Kidney; Male; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1987 |
Alpha-adrenergic and serotonergic mechanisms in the human digit.
Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Fingers; Humans; Ketanserin; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reflex; Regional Blood Flow; Serotonin; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction; Yohimbine | 1988 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |
Differential inhibitory effects of nitroglycerin on contractile responses to the alpha-adrenoceptor agonists, methoxamine and clonidine, in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Radioisotopes; Clonidine; Egtazic Acid; In Vitro Techniques; Lanthanum; Male; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Phenoxybenzamine; Potassium; Prazosin; Rabbits; Yohimbine | 1989 |
Decreased density of alpha 2-adrenoceptors in medulla oblongata of spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Clonidine; Hypertension; Medulla Oblongata; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; S-Adenosylmethionine | 1989 |
[Inhibitory action of intracerebroventricular injections of norepinephrine and clonidine on ventricular extrasystoles induced by stimulating hypothalamus in rabbits].
Topics: Animals; Cardiac Complexes, Premature; Clonidine; Electric Stimulation; Female; Hypothalamus; Injections, Intraventricular; Male; Norepinephrine; Phentolamine; Prazosin; Rabbits; Yohimbine | 1989 |
Regression of cardiac hypertrophy: experimental and clinical results.
Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats, Inbred SHR | 1987 |
TRH-catecholamine interactions in brain and spinal cord.
Topics: Animals; Catecholamines; Cerebral Ventricles; Clonidine; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Stereotyped Behavior; Thyrotropin-Releasing Hormone | 1989 |
Continuous monitoring of ventilation in spontaneously breathing anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Cardiovascular Agents; Clonidine; Codeine; Heart Rate; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Respiration; Respiratory Function Tests; Thyrotropin-Releasing Hormone; Tidal Volume | 1989 |
Identification of alpha 2-adrenergic receptor sites in human retinoblastoma (Y-79) and neuroblastoma (SH-SY5Y) cells.
Topics: Binding, Competitive; Cell Membrane; Clonidine; Epinephrine; Guanylyl Imidodiphosphate; Humans; Neuroblastoma; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Retinoblastoma; Sodium; Tritium; Tumor Cells, Cultured; Yohimbine | 1989 |
Mechanism of neuropeptide Y inhibition of vasopressin action in rat cortical collecting tubule.
Topics: Animals; Arginine Vasopressin; Clonidine; Cyclic AMP; Drug Interactions; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Neuropeptide Y; Pertussis Toxin; Prazosin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella; Yohimbine | 1989 |
Alpha 2-adrenergic modulation of synaptic excitability in the rat nucleus tractus solitarius.
Topics: Action Potentials; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Medulla Oblongata; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Amphetamine antagonizes the presynaptic inhibitory effect of clonidine through an interaction at the level of the alpha 2-adrenoceptors.
Topics: Amphetamine; Animals; Binding, Competitive; Clonidine; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens | 1989 |
Presynaptic alpha 2-adrenoceptor modulation of 5-hydroxytryptamine and noradrenaline release from vascular adrenergic nerves.
Topics: Animals; Azepines; Clonidine; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Splanchnic Circulation; Sympathetic Nervous System; Synapses | 1989 |
Lack of evidence for alpha-adrenergic receptor-mediated mechanisms in the genesis of ischemia in syndrome X.
Topics: Adult; Angina Pectoris; Clonidine; Coronary Angiography; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Syndrome | 1989 |
Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Regression Analysis | 1989 |
Changes in cortical acetylcholine and gamma-aminobutyric acid outflow during morphine withdrawal involve alpha-1 and alpha-2 receptors.
Topics: Acetylcholine; Animals; Clonidine; Dioxanes; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Naloxone; Prazosin; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome | 1989 |
The role of alpha- and beta-adrenoceptors in the response to noradrenaline of lymphatic vessels isolated from the bovine mesentery.
Topics: Animals; Cattle; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Lymphatic System; Mesentery; Methoxamine; Norepinephrine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1989 |
Altered adrenergic response and specificity of the receptors in rat ascites hepatoma AH130.
Topics: Adenylyl Cyclases; Albuterol; Animals; Cell Line; Clonidine; Enzyme Activation; Epinephrine; Iodocyanopindolol; Isoproterenol; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Metoprolol; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
Modulation of noradrenaline release in slices of rat kidney cortex through alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Indomethacin; Kidney Cortex; Male; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Theophylline | 1989 |
Alpha-adrenergic influences on neuronal responses to visceral afferent input in the nucleus tractus solitarius.
Topics: Animals; Clonidine; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; In Vitro Techniques; Male; Medulla Oblongata; Methoxamine; Neurons, Afferent; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Alpha 1-adrenergic receptor binding sites in post-mortal human cerebral microvessel preparations: preservation in multi-infarct dementia and dementia of Alzheimer type.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Cerebrovascular Circulation; Clonidine; Dementia; Humans; Microcirculation; Postmortem Changes; Prazosin; Receptors, Adrenergic, alpha | 1989 |
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha 1-adrenoreceptor blocking activity.
Topics: Adrenergic alpha-Antagonists; Animals; Chemical Phenomena; Chemistry; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Structure-Activity Relationship | 1989 |
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
An in vivo evaluation of alpha adrenergic receptors in canine prostate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Clonidine; Dogs; Dose-Response Relationship, Drug; Epinephrine; Male; Prazosin; Pressure; Prostate; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Dependence on extracellular potassium of the positive inotropic response to St 587, a selective alpha-1 adrenoceptor agonist, in Zucker rat heart ventricle.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Cell Membrane; Clonidine; Heart Ventricles; Myocardial Contraction; Obesity; Phosphatidylinositols; Potassium; Prazosin; Rats; Rats, Zucker; Stimulation, Chemical | 1989 |
Central alpha 1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cataplexy; Clonidine; Dioxanes; Dogs; Narcolepsy; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Sleep, REM | 1989 |
Alpha-blocking potencies of antihypertensive agents (prazosin, terazosin, bunazosin, SGB-1534 and ketanserin) having with quinazoline or quinazolinedione as assessed by radioligand binding assay methods in rat brain.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brain; Cell Membrane; Clonidine; Dihydroalprenolol; Ketanserin; Male; Prazosin; Quinazolines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1989 |
An in vivo procedure for the selective inactivation of rat brain cerebral cortical alpha-adrenoceptors using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ).
Topics: Adrenergic alpha-Antagonists; Animals; Cell Membrane; Cerebral Cortex; Clonidine; Cyclic AMP; Dihydroalprenolol; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Prazosin; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Characterization of autonomic receptors in neonatal urinary tract smooth muscle.
Topics: Adrenergic Agonists; Animals; Animals, Newborn; Carbachol; Clonidine; Dihydroalprenolol; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prazosin; Quinuclidinyl Benzilate; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Urinary Tract; Yohimbine | 1989 |
Discriminative stimulus effects of the alpha 2-adrenoceptor antagonist idazoxan.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dioxins; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Idazoxan; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1989 |
Effects of St-587 on the alpha-adrenoceptors in the bisected rat vas deferens.
Topics: Animals; Clonidine; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Prazosin; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1989 |
Stimulation of alpha 1-adrenoceptors increases electrically evoked [3H]acetylcholine release from the rat phrenic nerve.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; Oxymetazoline; Phenylephrine; Phrenic Nerve; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Involvement of noradrenergic system in a remarkably rapid tongue clonus produced by acute hypnotic doses of ethanol in Fischer F344 rats.
Topics: Animals; Brain Chemistry; Clonidine; Ethanol; Hypnotics and Sedatives; Male; Muscles; Norepinephrine; Pimozide; Prazosin; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tongue | 1989 |
Centrally acting alpha-2 agonists, peripherally acting adrenergic-blocking drugs, and direct vasodilators in the treatment of mild and moderate essential hypertension.
Topics: Adult; Aged; Black People; Clinical Protocols; Clonidine; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin | 1989 |
Therapy of venous hypertension in calves with total artificial heart (TAH).
Topics: Animals; Antihypertensive Agents; Captopril; Cardiac Pacing, Artificial; Cattle; Central Venous Pressure; Clonidine; Heart, Artificial; Hypertension; Liver Function Tests; Methyldopa; Nifedipine; Postoperative Complications; Prazosin | 1989 |
Serotonin release mechanisms in bovine pineal gland: stimulation by norepinephrine and dopamine.
Topics: Animals; Benzazepines; Calcium; Cattle; Clonidine; Dopamine; Dopamine Antagonists; Haloperidol; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Serotonin; Sulpiride | 1989 |
[Therapy of venous hypertension in animals with an artificial heart and long-term survival].
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Clonidine; Diltiazem; Heart, Artificial; Methyldopa; Nifedipine; Prazosin; Venous Pressure | 1989 |
New isoxazole derivatives provided with antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Chemical Phenomena; Chemistry; Clonidine; In Vitro Techniques; Isoxazoles; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxazoles; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vas Deferens; Yohimbine | 1989 |
Restraint-stress-induced changes in exploratory behavior appear to be mediated by norepinephrine-stimulated release of CRF.
Topics: Animals; Benzylamines; Biogenic Amines; Brain; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Exploratory Behavior; Male; Mice; Mice, Inbred Strains; Neurotoxins; Norepinephrine; Phenylephrine; Prazosin; Restraint, Physical; Stress, Physiological | 1989 |
[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord].
Topics: Animals; Cats; Clonidine; Mesencephalon; Naloxone; Neurons; Nociceptors; Pain; Prazosin; Spinal Cord; Yohimbine | 1989 |
Characterization of alpha-adrenoceptor subtypes involved in regulation of ureteral fluid transport.
Topics: Animals; Clonidine; Dogs; Female; Male; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Ureter; Yohimbine | 1987 |
Characterisation of the alpha-adrenoceptors of the rat renal vascular bed.
Topics: Animals; Azepines; Clonidine; Dopamine; In Vitro Techniques; Kidney; Male; Nordefrin; Perfusion; Phenylephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1987 |
Identification and characterization of alpha 1 adrenergic receptors in the canine prostate using [125I]-Heat.
Topics: Animals; Binding, Competitive; Clonidine; Dogs; Iodine Radioisotopes; Ligands; Male; Phenethylamines; Phentolamine; Prazosin; Prostate; Radioligand Assay; Receptors, Adrenergic, alpha; Tetralones; Time Factors | 1987 |
Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.
Topics: Algorithms; Animals; Binding, Competitive; Cattle; Clonidine; Hydrogen-Ion Concentration; Prazosin; Quinolizines; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine | 1988 |
Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Conductivity; Epinephrine; Isoproterenol; Phenylephrine; Pigment Epithelium of Eye; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Alpha 1- and alpha 2-noradrenergic receptor binding in guinea pig brain: sex differences and effects of ovarian steroids.
Topics: Animals; Brain; Clonidine; Estradiol; Female; Guinea Pigs; Kinetics; Male; Organ Specificity; Prazosin; Receptors, Adrenergic, alpha; Reference Values; Sex Factors | 1988 |
Binding of [3H]prazosin and [3H]p-aminoclonidine to alpha-adrenoceptors in rat spinal cord.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord | 1988 |
Role of alpha 1- and alpha 2-adrenoceptors in catecholamine-induced hyperglycaemia, lipolysis and insulin secretion in conscious fasted rabbits.
Topics: Animals; Catecholamines; Clonidine; Hyperglycemia; Insulin; Insulin Secretion; Lipolysis; Male; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Alpha 2-adrenoceptor activity exerts dual control of coronary blood flow in canine coronary artery.
Topics: Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Vessels; Dogs; Norepinephrine; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Vasodilation; Yohimbine | 1988 |
Role of alpha-adrenoceptor subtypes mediating sympathetic vasoconstriction in human digits.
Topics: Adult; Clonidine; Female; Fingers; Humans; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1988 |
Sites of clonidine action to inhibit gut propulsion in mice: demonstration of a central component.
Topics: Animals; Clonidine; Gastrointestinal Transit; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Prazosin; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1988 |
Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Dioxanes; Drug Tolerance; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Characterization of adrenergic receptors on proximal tubular basolateral membranes.
Topics: Animals; Cell Membrane; Clonidine; Dihydroalprenolol; Dihydroergotoxine; Kidney Tubules, Proximal; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Behavioural and electrocortical spectrum-power effects of clonidine and related drugs given into several areas of the rat brain.
Topics: Animals; Behavior, Animal; Clonidine; Electroencephalography; Injections, Intraventricular; Locus Coeruleus; Male; Methoxamine; Microinjections; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1988 |
Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex.
Topics: Animals; Autoradiography; Cerebral Cortex; Clonidine; Female; Flunitrazepam; Ketanserin; Macaca mulatta; Male; Muscimol; Pindolol; Prazosin; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Neurotransmitter; Serotonin; Spiperone; Visual Cortex | 1988 |
Unique presynaptic alpha 2-receptor selectivity and specificity of the antihypertensive agent moxonidine.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cerebral Cortex; Chemical Phenomena; Chemistry; Clonidine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Heart Rate; Imidazoles; Ligands; Male; Norepinephrine; Papillary Muscles; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Venae Cavae; Yohimbine | 1988 |
[Changes in the sensitivity of the alpha 2- and beta 1-adrenoreactive systems during the intensive cooling of rats acclimatized to cold].
Topics: Acclimatization; Animals; Clonidine; Cold Temperature; Female; Heart Rate; Hypothermia; Isoproterenol; Male; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1988 |
Dose selective dissociation of water and solute excretion after renal alpha-2 adrenoceptor stimulation.
Topics: Animals; Blood Pressure; Body Water; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasopressins; Yohimbine | 1988 |
Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.
Topics: Adenosine; Aggression; Animals; Behavior, Animal; Caffeine; Carbamazepine; Clonidine; Haloperidol; Male; Mice; Prazosin; Receptors, Cell Surface; Yohimbine | 1988 |
Alpha-2-adrenoceptor-mediated inhibition of vagally induced gastric acid secretion with the anti-ulcer agent DQ-2511.
Topics: Animals; Anti-Ulcer Agents; Benzamides; Clonidine; Gastric Acid; Gastric Mucosa; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Vagus Nerve; Yohimbine | 1988 |
Alpha 1- and alpha 2-noradrenergic receptors in steroid-sensitive brain areas: development and response to estradiol-17 beta benzoate in neonatal guinea pigs.
Topics: Animals; Animals, Newborn; Brain; Clonidine; Estradiol; Female; Guinea Pigs; Kinetics; Ovariectomy; Prazosin; Receptors, Adrenergic, alpha; Reference Values | 1988 |
Enhancement of endogenous GABA release from rat synaptosomal preparations is mediated by alpha 2-adrenoceptors pharmacologically different from alpha 2-autoreceptors.
Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Male; Mianserin; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1988 |
Direct and indirect effects of alprazolam and imipramine on alpha 1- and alpha 2-adrenoceptors in mouse forebrain.
Topics: Alprazolam; Animals; Binding, Competitive; Brain Chemistry; Clonidine; Imipramine; Male; Mice; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Calcium Chloride; Clonidine; Endothelium; In Vitro Techniques; Male; Methoxamine; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Yohimbine | 1985 |
Alpha 2-adrenoceptor blocking properties of the alpha 1-selective agonist 2-(2-chloro-5-trifluoromethylphenylimino)imidazolidine (St 587).
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Behavior, Animal; Clonidine; Dogs; Drug Interactions; Electric Stimulation; Exploratory Behavior; Female; Heart Rate; Male; Mice; Prazosin; Pressoreceptors; Rats; Spinal Cord; Vagotomy | 1985 |
Adrenergic receptors in frontal cortex in human brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Dihydroalprenolol; Frontal Lobe; Humans; Kinetics; Postmortem Changes; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tritium | 1985 |
Recovery of alpha-adrenoreceptor mediated responses and binding site number after intravenous benextramine in the rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain; Clonidine; Cystamine; Injections, Intravenous; Male; Membranes; Phenoxybenzamine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spleen; Time Factors | 1985 |
Sodium chloride-induced partial inhibition in vivo of alpha 2-adrenoceptor agonist function.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Male; Mannitol; Nephrectomy; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Chloride; Yohimbine | 1985 |
Peripheral cardiovascular alpha- and beta-adrenergic effects of some hypotensive and bradycardic arylalkyl imidazole derivatives in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart; Imidazoles; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1985 |
Pharmacological characterization of alpha-adrenergic receptor subtypes mediating contraction in human mesenteric arteries and veins.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Drug Interactions; Female; Humans; Male; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phentolamine; Prazosin; Vasodilation; Yohimbine | 1985 |
Differences in response of black hypertensives to alpha vs. beta adrenergic antagonists: preliminary findings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Black People; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Posture; Prazosin | 1985 |
Arylazide photoaffinity probe for alpha 2-adrenoceptors.
Topics: Absorption; Adrenergic alpha-Antagonists; Benzazepines; Binding, Competitive; Blood Platelets; Clonidine; Humans; Membranes; Phentolamine; Photolysis; Prazosin; Receptors, Adrenergic, alpha; Tritium; Ultraviolet Rays; Yohimbine | 1985 |
Alpha 1-adrenergic blockade increases coronary blood flow during coronary hypoperfusion.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Coronary Circulation; Dogs; Drug Synergism; Female; Male; Methoxamine; Perfusion; Prazosin; Propranolol; Yohimbine | 1985 |
Effects of alpha-adrenoceptor agonists and antagonists on insulin secreting cells and pancreatic blood vessels: comparative study.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Clonidine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Yohimbine | 1985 |
Inhibitory effect of alpha-1 adrenoceptor stimulation on cardiac sympathetic neurotransmission in pithed normotensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Decerebrate State; Ethanolamines; Heart; Heart Rate; Imidazoles; Male; Prazosin; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synaptic Transmission | 1986 |
Imidazole has similar behavioural effects to yohimbine.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Azepines; Behavior, Animal; Body Temperature; Chickens; Clonidine; Haloperidol; Hypnotics and Sedatives; Imidazoles; Male; Penile Erection; Prazosin; Rats; Sexual Behavior, Animal; Sleep; Time Factors; Yohimbine | 1986 |
Current concepts in treatment of hypertensive urgencies.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Central Nervous System; Clonidine; Diuretics; Ganglia; Guanethidine; Humans; Hypertension; Labetalol; Minoxidil; Patient Compliance; Prazosin; Sympatholytics; Vasodilator Agents | 1986 |
Adrenoceptor blocking properties of the stereoisomers of amosulalol (YM-09538) and the corresponding desoxy derivative (YM-11133).
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Brain; Clonidine; Dose-Response Relationship, Drug; Ethanolamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenethylamines; Prazosin; Rabbits; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Stereoisomerism | 1986 |
Phenoxybenzamine partially inhibits alpha 2-adrenoceptors without affecting their presynaptic function.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; In Vitro Techniques; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
The alpha 1- and alpha 2-adrenoceptor selectivity of drugs with potential effects on blood pressure--a radioligand-binding study.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Imidazoles; Indoramin; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha | 1986 |
Effects of nipradilol (K-351) on alpha-adrenoceptor mediated responses in various isolated tissues.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Dogs; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Nitroglycerin; Phentolamine; Prazosin; Propanolamines; Rabbits; Rats; Receptors, Adrenergic, alpha; Saphenous Vein; Vas Deferens | 1985 |
[Therapy of chronic heart failure with vasodilators].
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Clonidine; Heart Failure; Hemodynamics; Humans; Myocardial Contraction; Prazosin; Saralasin; Vascular Resistance; Vasodilator Agents | 1986 |
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; Decerebrate State; Female; Heart Rate; Hexobarbital; In Vitro Techniques; Male; Mice; Oxazoles; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rilmenidine; Sleep; Time Factors | 1986 |
Blockade of postsynaptic alpha 2-adrenoceptors enhances responses to mixed alpha 1/alpha 2-agonists in rat submaxillary gland.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Isoproterenol; Nordefrin; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Saliva; Submandibular Gland | 1986 |
Protein secretion in lacrimal gland: alpha 1-beta-adrenergic synergism.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Epinephrine; Imidazoles; Isoproterenol; Kinetics; Lacrimal Apparatus; Male; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1986 |
Presynaptic alpha-adrenoceptor mediated inhibition of the neurogenic cholinergic contraction in the isolated intestinal bulb of the carp (Cyprinus carpio).
Topics: Animals; Atropine; Carps; Catecholamines; Clonidine; Cyprinidae; Electric Stimulation; Epinephrine; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Yohimbine | 1986 |
The effects of alpha 2 adrenoceptor agonists on airway pressure in anaesthetized sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Airway Resistance; Animals; Clonidine; Dioxanes; Female; Histamine; Idazoxan; Injections, Intravenous; Injections, Intraventricular; Methoxamine; Prazosin; Pyrilamine; Sheep; Tripelennamine; Xylazine | 1986 |
Alpha-2 adrenergic agonists inhibit basal and stimulated osmotic water permeability in toad skin.
Topics: Adrenergic alpha-Agonists; Animals; Bufo arenarum; Clonidine; Female; In Vitro Techniques; Male; Norepinephrine; Osmolar Concentration; Oxytocin; Permeability; Prazosin; Propranolol; Skin; Skin Physiological Phenomena; Water; Yohimbine | 1986 |
L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Male; Mydriatics; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Vas Deferens; Yohimbine | 1986 |
Pharmacological characterization of the postsynaptic alpha-adrenoceptors in human uterine artery.
Topics: Arteries; Clonidine; Drug Interactions; Female; Humans; Kinetics; Naphazoline; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Uterus; Vasoconstriction; Yohimbine | 1986 |
Possible involvement of presynaptic alpha 1-adrenoceptors in the effects of idazoxan and prazosin on 3H-noradrenaline release from tail arteries of SHR.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Pharmacological characterization of spinal alpha adrenoceptors related to blood pressure control in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain Stem; Clonidine; Dopamine; Guanabenz; Hydroxydopamines; Injections, Spinal; Male; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1987 |
The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dioxanes; Female; Idazoxan; Isoquinolines; Male; Medulla Oblongata; Piperazines; Prazosin; Yohimbine | 1987 |
Pharmacological manipulations of alpha-adrenoceptors in the infant rat and effects on growth hormone secretion. Study of the underlying mechanisms of action.
Topics: Animals; Animals, Newborn; Clonidine; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Immune Sera; Male; Methoxamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Somatostatin; Yohimbine | 1987 |
Effects of alpha 1- and alpha 2-adrenoceptor stimulation and blockade on plasma insulin levels in the mouse.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Female; Glucose; Insulin; Insulin Secretion; Mice; Phenylephrine; Prazosin; Radioimmunoassay; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Arousal; Clonidine; Electroencephalography; Injections, Intraventricular; Locus Coeruleus; Male; Methoxamine; Microinjections; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep; Yohimbine | 1987 |
Mediation of separation distress by alpha 2-adrenergic mechanisms in a non-human primate.
Topics: Adrenergic alpha-Agonists; Animals; Anxiety, Separation; Clonidine; Imipramine; Male; Prazosin; Receptors, Adrenergic, alpha; Saimiri; Vocalization, Animal; Yohimbine | 1987 |
[Effects of intravenous and intracerebroventricular terazosin, prazosin and clonidine on spontaneous sympathetic outflow in rats].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Clonidine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1987 |
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1987 |
Effects of DJ-7141, a new peripherally acting alpha-2 adrenoceptor agonist, on blood pressure and gastric acid output in rats: evidence for the heterogeneity of alpha-2 adrenoceptors in different organs.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Gastric Acid; Imidazoles; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Splanchnic Nerves; Yohimbine | 1987 |
Alpha-adrenergic inhibition of rat cerebellar Purkinje cells in vitro: a voltage-clamp study.
Topics: Adrenergic alpha-Agonists; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cerebellum; Clonidine; Electric Conductivity; Membrane Potentials; Phentolamine; Prazosin; Purkinje Cells; Rats; Tetrodotoxin; Yohimbine | 1987 |
Postsynaptic effects of alpha agonists on adrenoceptors of the reserpinized rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Drug Interactions; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reserpine; Vas Deferens; Yohimbine | 1987 |
Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Blood Platelets; Cattle; Cerebral Cortex; Clonidine; Humans; In Vitro Techniques; Ketanserin; Male; Prazosin; Quinolizines; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Vas Deferens | 1987 |
Is there a role for renal alpha 2-adrenoceptors in the pathogenesis of hypertension?
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Gluconeogenesis; Guanfacine; Guanidines; Hypertension; In Vitro Techniques; Kidney; Methoxamine; Norepinephrine; Parathyroid Glands; Phenylacetates; Prazosin; Pyruvates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Vascular Resistance; Yohimbine | 1987 |
Postnatal treatment of rats with adrenergic receptor agonists or antagonists influences differentiation of sexual behavior.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Body Weight; Clonidine; Female; Male; Organ Size; Ovariectomy; Ovary; Posture; Prazosin; Rats; Rats, Inbred Strains; Sex Characteristics; Sexual Behavior, Animal; Testosterone; Yohimbine | 1987 |
The adrenergic agonist tizanidine has differential effects on flexor reflexes of intact and spinalized rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electromyography; Muscle Contraction; Prazosin; Reaction Time; Reflex; Spinal Cord; Yohimbine | 1987 |
Action of rilmenidine on locus ceruleus and dorsal raphe cells in vivo and in vitro.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Clonidine; In Vitro Techniques; Infusions, Intravenous; Iontophoresis; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Oxazoles; Prazosin; Raphe Nuclei; Rats; Rats, Inbred Strains; Rilmenidine | 1988 |
2,4-Diamino-6,7-dimethoxyquinazolines. 4. 2-[4-(substituted oxyethoxy) piperidino] derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Half-Life; Hydrogen-Ion Concentration; Prazosin; Quinazolines; Rabbits | 1988 |
Electrophysiological evidence for alpha 1- and alpha 2-adrenoceptors in solitary tract nucleus.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; Idazoxan; Male; Medulla Oblongata; Methoxamine; Neurons; Norepinephrine; Prazosin; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex | 1988 |
Chronic prazosin attenuates the natriuretic response to a modest saline load in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Clonidine; Kidney; Natriuresis; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Sodium Chloride | 1988 |
Blocking action of berberine on alpha 2- and alpha 1-adrenoceptors in rat vas deferens and anococcygeus muscle.
Topics: Adrenergic alpha-Antagonists; Anal Canal; Animals; Berberine; Berberine Alkaloids; Clonidine; Dose-Response Relationship, Drug; Male; Muscle, Smooth; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1987 |
Prejunctional alpha 2-adrenergic properties of S-3341 (dicyclopropylmethyl)amino-2-delta-2-oxazoline: a comparison with clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Oxazoles; Prazosin; Rats; Rats, Inbred WKY; Rilmenidine; Vas Deferens; Yohimbine | 1987 |
Relationship of alpha-1- and alpha-2-adrenergic-binding sites to regions of the paraventricular nucleus of the hypothalamus containing corticotropin-releasing factor and vasopressin neurons.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Clonidine; Corticotropin-Releasing Hormone; Immunohistochemistry; Ligands; Male; Neurons; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasopressins | 1988 |
Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brain; Brimonidine Tartrate; Clonidine; Female; Imidazoles; In Vitro Techniques; Male; Medetomidine; Muscle, Smooth; Mydriatics; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1988 |
Effect of 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monophydrochloride (SGB-1534), an antihypertensive agent, on 3H-prazosin and 3H-p-aminoclonidine binding to alpha 1- and alpha 2-adrenoceptors in dog brain and aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brain; Clonidine; Dogs; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prazosin; Quinazolines; Receptors, Adrenergic, alpha | 1988 |
Precontraction-induced contractile response of isolated canine portal vein to alpha-2 adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcimycin; Cats; Clonidine; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Yohimbine | 1988 |
Antagonism of clonidine-induced hypothermia by alpha adrenoceptor antagonists in electrically stimulated mice.
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Electroshock; Fever; Male; Mice; Mice, Inbred Strains; Phenoxybenzamine; Prazosin; Yeasts; Yohimbine | 1988 |
Release of [3H]-noradrenaline from the sympathetic nerves to bovine mesenteric lymphatic vessels and its modification by alpha-agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cocaine; Electric Stimulation; Feedback; Lymphatic System; Mesentery; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Xylazine; Yohimbine | 1988 |
Enhanced vascular alpha-adrenergic neuroeffector system in diabetes: importance of calcium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; Guanabenz; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Interaction between clozapine and a lipophilic alpha 1-adrenergic agonist.
Topics: Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Clozapine; Dextroamphetamine; Dibenzazepines; Drug Interactions; Drug Tolerance; Male; Methoxamine; Mice; Motor Activity; Prazosin | 1988 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Effects of cooling on alpha-1-adrenoceptor mechanisms in rat aorta.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Cold Temperature; In Vitro Techniques; Male; Microsomes; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Effect of clonidine on ultrasonic vocalization in preweaning rats.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Body Temperature; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Hot Temperature; Idazoxan; Prazosin; Rats; Rats, Inbred Strains; Reference Values; Ultrasonics; Vocalization, Animal | 1988 |
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Central and peripheral inhibition of exocrine pancreatic secretion by alpha-2 adrenergic agonists in the rat.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Clonidine; Male; Pancreas; Prazosin; Rats; Rats, Inbred Strains | 1988 |
Effects of alpha 1 adrenoceptor activation on the excitability of primary afferent terminals of the sural nerve in the spinal cord of the cat.
Topics: Adrenergic alpha-Agonists; Afferent Pathways; Animals; Cats; Clonidine; Neural Conduction; Prazosin; Receptors, Adrenergic, alpha; Reference Values; Spinal Cord; Spinal Nerves; Sural Nerve | 1988 |
Stereoselective blockade of alpha-adrenoceptors by berbine derivatives.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Berberine Alkaloids; Binding, Competitive; Blood Pressure; Chemical Phenomena; Chemistry; Clonidine; Heart Rate; Ligands; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Dipropylacetate-induced shaking behaviour in the rat: a role of spinal alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Dioxanes; Idazoxan; Injections, Intraventricular; Male; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Valproic Acid | 1988 |
No evidence for more than one type of alpha 1-adrenoreceptor in rabbit pulmonary artery.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Male; Methoxamine; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1988 |
[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects].
Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Cardiomyopathy, Hypertrophic; Clonidine; Coronary Circulation; Heart Failure; Heart Ventricles; Humans; Hypertension; Nifedipine; Prazosin; Prognosis; Sympathetic Nervous System; Vascular Resistance | 1985 |
[Hemodynamic effect of a combination of prazosin with cardiac depressants in the treatment of hypertension].
Topics: Anti-Arrhythmia Agents; Celiprolol; Clonidine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Prazosin; Propanolamines; Propranolol; Verapamil | 1988 |
Postjunctional alpha-1 and alpha-2 adrenoceptors in the coronaries of the perfused guinea-pig heart.
Topics: Animals; Azepines; Clonidine; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nordefrin; Norepinephrine; Perfusion; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1985 |
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Tolazoline; Yohimbine | 1985 |
Characterization of the alpha adrenergic receptor population in hippocampus up regulated by serotonergic raphe deafferentiation.
Topics: Animals; Clonidine; Dioxanes; Female; Guanylyl Imidodiphosphate; Hippocampus; Kinetics; Norepinephrine; Prazosin; Propranolol; Raphe Nuclei; Rats; Receptors, Adrenergic, alpha; Serotonin; Sodium; Yohimbine | 1985 |
Evaluation of the alpha 1- and alpha 2-adrenoceptor effects of detomidine, a novel veterinary sedative analgesic.
Topics: Analgesics; Animals; Clonidine; Electric Stimulation; Female; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Muscle Contraction; Muscle, Smooth; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Xylazine | 1985 |
Alpha-adrenergic receptor changes during antidepressant treatment.
Topics: Animals; Antidepressive Agents; Clonidine; Prazosin; Rats; Receptors, Adrenergic, alpha | 1985 |
Interference of enantiomers of lofexidine with alpha-adrenoceptors.
Topics: Animals; Binding, Competitive; Blood Pressure; Clonidine; Electric Stimulation; Heart Rate; Hemodynamics; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism | 1985 |
Adrenergic receptors on cerebral microvessels in control and parkinsonian subjects.
Topics: Aged; Alprenolol; Capillaries; Cerebrovascular Circulation; Clonidine; Dihydroalprenolol; Humans; Kinetics; Parkinson Disease; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reference Values | 1985 |
Evidence for the modulation of sexual behavior by alpha-adrenoceptors in male rats.
Topics: Animals; Clonidine; Copulation; Drug Interactions; Ejaculation; Kinetics; Male; Prazosin; Rats; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1985 |
Regulation of central alpha-adrenoceptors by serotoninergic denervation.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Cerebral Cortex; Clonidine; Hippocampus; Hypothalamus; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin | 1985 |
The effects of phenoxybenzamine on specific binding and function of central alpha-adrenoceptors in the rabbit.
Topics: Animals; Brain; Clonidine; Dactinomycin; Drug Interactions; Fluorouracil; Male; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1985 |
Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures.
Topics: Animals; Brain Chemistry; Clonidine; Diazepam; Haloperidol; Kainic Acid; Male; Metergoline; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures | 1985 |
Postsynaptic alpha 2-noradrenergic receptors mediate feeding induced by paraventricular nucleus injection of norepinephrine and clonidine.
Topics: Animals; Clonidine; Injections; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tryptamines; Yohimbine | 1985 |
Postsynaptic alpha adrenoceptors in baboon cerebral and mesenteric arteries.
Topics: Animals; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Norepinephrine; Papio; Phentolamine; Phenylephrine; Potassium Chloride; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1985 |
A strong influence of serotonin axons on beta-adrenergic receptors in rat brain.
Topics: Animals; Axons; Cerebral Cortex; Clonidine; Dihydroalprenolol; Hippocampus; Kinetics; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin | 1985 |
Altered postnatal ontogeny of alpha 1- and alpha 2-adrenoceptor binding sites in the brain of a convulsive mutant mouse (quaking).
Topics: Animals; Brain; Brain Chemistry; Clonidine; Dihydroalprenolol; Female; Male; Mice; Mice, Inbred C57BL; Mice, Quaking; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Seizures | 1985 |
Dual effects of clonidine on micturition reflex in urethane anesthetized rats.
Topics: Anesthesia; Animals; Clonidine; Electric Stimulation; Hydroxydopamines; Injections, Intraventricular; Male; Muscle Contraction; Oxidopamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sympathectomy, Chemical; Synaptic Transmission; Urethane; Urinary Bladder; Urination; Yohimbine | 1985 |
Epinephrine-stimulated maintained rubidium efflux from guinea pig hepatocytes may involve alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Calcium; Clonidine; Epinephrine; Guinea Pigs; In Vitro Techniques; Liver; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Rubidium; Yohimbine | 1985 |
Abnormality of alpha 1-adrenergic receptors in the frontal cortex of epileptic rats.
Topics: Animals; Carbachol; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Inferior Colliculi; Male; Norepinephrine; Phentolamine; Phosphatidylinositols; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine | 1986 |
N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin -2-yl)-N- methyl-2-hydroxyethane-sulfonamide: a potent and selective alpha 2-adrenoceptor antagonist.
Topics: Animals; Binding, Competitive; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Clonidine; Male; Prazosin; Pupil; Quinolizines; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Yohimbine | 1985 |
Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates.
Topics: Aging; Animals; Cerebral Cortex; Clonidine; Cognition; Female; Hydroxydopamines; Macaca mulatta; Memory; Oxidopamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Alteration of alpha and muscarinic receptors in rat brain and heart following chronic nicotine treatment.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Clonidine; Hypothalamus; Male; Myocardium; Nicotine; Prazosin; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Thalamus; Time Factors | 1985 |
Alpha adrenoceptor subtype mediating sympathetic mobilization of blood from the hepatic venous system in anesthetized cats.
Topics: Anesthesia; Animals; Blood Volume; Cats; Clonidine; Electric Stimulation; Hepatic Veins; Nordefrin; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1986 |
Modulation of alpha 1-and alpha 2-adrenoceptor binding sites in the brain of audiogenic seizure susceptible mice (DBA/2J).
Topics: Acoustic Stimulation; Animals; Brain; Clonidine; Dihydroalprenolol; Female; Kinetics; Male; Mice; Mice, Inbred DBA; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Seizures; Species Specificity | 1985 |
Central adrenergic receptor control of renal function in conscious hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urodynamics; Yohimbine | 1986 |
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Repeated treatment with clenbuterol produces desensitization of rat brain beta- and alpha 2-adrenoceptors without changes of alpha 1-adrenoceptors.
Topics: Animals; Clenbuterol; Clonidine; Dihydroalprenolol; Ethanolamines; Exploratory Behavior; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors | 1986 |
Pre- and postjunctional alpha-adrenoceptors at sympathetic neuroeffector junction in bovine mesenteric lymphatics.
Topics: Adrenergic Fibers; Animals; Cattle; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lymphatic System; Mesentery; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Transmission; Time Factors; Tritium | 1986 |
Impact of circulating corticosterone on alpha 1- and alpha 2-noradrenergic receptors in discrete brain areas.
Topics: Adrenalectomy; Animals; Brain Chemistry; Clonidine; Corticosterone; Hypothalamus; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1986 |
Effects of chemical sympathectomy with 6-hydroxydopamine on alpha- and beta-adrenoceptors and muscarinic cholinoceptors in rat kidney.
Topics: Animals; Clonidine; Dihydroalprenolol; Hydroxydopamines; In Vitro Techniques; Kidney; Kinetics; Male; Norepinephrine; Oxidopamine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Sympathectomy, Chemical | 1986 |
Studies that question the existence of alpha-2 adrenoceptors in tail arteries of normotensive Sprague-Dawley rats.
Topics: Animals; Arteries; Azepines; Clonidine; Dose-Response Relationship, Drug; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tail; Vasoconstriction; Yohimbine | 1986 |
Activation of alpha 2-adrenoreceptors enhances haloperidol-induced suppression of operant behavior.
Topics: Animals; Behavior, Animal; Brain Chemistry; Clonidine; Conditioning, Operant; Dihydroxyphenylalanine; Dioxanes; Drug Interactions; Haloperidol; Idazoxan; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1986 |
Involvement of postsynaptic alpha 1- and alpha 2-adrenoceptors in the flexor reflex activity in the spinal rats.
Topics: Animals; Clonidine; Clozapine; Decerebrate State; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Spinal Cord; Yohimbine | 1986 |
Studies on epinephrine-induced lung edema in the rat. I. Selective alpha 1-adrenoceptor involvement.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Dibenzylchlorethamine; Epinephrine; Female; Metaraminol; Norepinephrine; Phenylephrine; Practolol; Prazosin; Propranolol; Pulmonary Edema; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Receptor protection experiments confirm the identity of presynaptic alpha 2-autoreceptors.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1986 |
Alpha 2-receptor control over release of noradrenaline in rat thalamus.
Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; In Vitro Techniques; Male; Norepinephrine; Potassium; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Thalamus; Yohimbine | 1986 |
Central alpha 2-adrenergic control of the pattern of small intestinal motility in rats.
Topics: Animals; Clonidine; Duodenum; Eating; Electromyography; Fasting; Gastrointestinal Motility; Jejunum; Male; Naphazoline; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Sympathetic and parasympathetic nerves regulate postsynaptic alpha-2 adrenoceptor in salivary glands.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Female; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Parasympathetic Nervous System; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Saliva; Salivary Glands; Sublingual Gland; Submandibular Gland; Sympathetic Nervous System | 1986 |
Adrenergic influences on sexual differentiation of the rat brain.
Topics: Animals; Brain; Clonidine; Feedback; Female; Posture; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sex Differentiation; Sexual Behavior, Animal; Testosterone; Yohimbine | 1986 |
Impact of food deprivation on alpha 1- and alpha 2-noradrenergic receptors in the paraventricular nucleus and other hypothalamic areas.
Topics: Animals; Clonidine; Dioxanes; Food Deprivation; Hypothalamus; Male; Paraventricular Hypothalamic Nucleus; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Satiety Response | 1986 |
Alpha adrenergic receptors mediate angiotensin-induced prostaglandin production in the rabbit isolated vas deferens.
Topics: Angiotensin II; Angiotensin III; Animals; Clonidine; Male; Muscle Contraction; Phenylephrine; Prazosin; Prostaglandins E; Rabbits; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1987 |
Postjunctional vascular smooth muscle alpha-2 adrenoreceptors in human autonomic failure.
Topics: Aged; Autonomic Nervous System Diseases; Blood Platelets; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Muscle, Smooth; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Evidence for the involvement of alpha-2 adrenoceptors in the sedation but not REM sleep inhibition by clonidine in the rat.
Topics: Animals; Clonidine; Electroencephalography; Hypnotics and Sedatives; Male; Phenoxybenzamine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep, REM; Yohimbine | 1986 |
Effect of the amino-oxazoline derivative S-3341 on pre- and postjunctional alpha-adrenoceptors in isolated blood vessels.
Topics: Animals; Clonidine; Dogs; In Vitro Techniques; Norepinephrine; Oxazoles; Perfusion; Phenylephrine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Saphenous Vein; Vasoconstriction; Yohimbine | 1986 |
Quantitative evaluation of alpha- and beta-adrenoceptor modulation of [3H]choline release in guinea pig superior cervical ganglia.
Topics: Acetylcholine; Animals; Choline; Clonidine; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1987 |
Noradrenergic regulation of cytosol estrogen receptors in female rat hypothalamus: possible role of alpha 2-noradrenergic receptors.
Topics: Animals; Cell Nucleus; Clonidine; Cytosol; Female; Hypothalamus; Norepinephrine; Osmolar Concentration; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Estrogen; Yohimbine | 1987 |
Fengabine, a novel antidepressant GABAergic agent. II. Effect on cerebral noradrenergic, serotonergic and GABAergic transmission in the rat.
Topics: Animals; Antidepressive Agents; Brain; Chlorophenols; Clonidine; Dihydroalprenolol; gamma-Aminobutyric Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spiperone; Synaptic Transmission | 1987 |
Postjunctional alpha 2-adrenoceptors in pial arteries of anesthetized newborn pigs.
Topics: Animals; Animals, Newborn; Cerebral Arteries; Clonidine; Female; Ganglia, Sympathetic; Male; Phenylephrine; Pia Mater; Prazosin; Receptors, Adrenergic, alpha; Swine; Vasoconstriction; Yohimbine | 1987 |
Alpha 2-adrenergic potentiation of adenosine-stimulating effect on glucagon secretion.
Topics: Adenosine; Animals; Clonidine; Drug Synergism; Epinephrine; Glucagon; Male; Pancreas; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Tissue-dependent alpha adrenoceptor activity of buspirone and related compounds.
Topics: Animals; Buspirone; Cerebral Cortex; Clonidine; Guinea Pigs; Male; Norepinephrine; Phenylephrine; Prazosin; Pyrimidines; Rabbits; Rats; Receptors, Adrenergic, alpha; Vas Deferens | 1987 |
Clonidine and prazosin block the iminodipropionitrile (IDPN)-induced spasmodic dyskinetic syndrome in mice.
Topics: Animals; Clonidine; Dyskinesia, Drug-Induced; Male; Mice; Nitriles; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha | 1987 |
Prazosin partly blocks clonidine-induced hypotension in patients with essential hypertension.
Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Prazosin; Receptors, Adrenergic, alpha | 1987 |
On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain; Clonidine; Endorphins; Heart Rate; Hypertension; Hypothalamus; Male; Naloxone; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1987 |
Effects of some antihypertensive drugs on cutaneous blood flow and inflammatory skin responses following allergen challenge in guinea pigs.
Topics: Allergens; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Clonidine; Dermatitis; Enalapril; Enalaprilat; Female; Guinea Pigs; Ovalbumin; Prazosin; Regional Blood Flow; Skin | 1987 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Penis; Phenylephrine; Practolol; Prazosin; Prenalterol; Procaterol; Receptors, Adrenergic; Receptors, Muscarinic; Yohimbine | 1985 |
Synchronizing effect of the alpha 1-adrenoceptor agonist 2-(2-chloro-5-trifluoromethylphenylimino)imidazolidine on rabbit electroencephalogram.
Topics: Animals; Blood Pressure; Clonidine; Electrocardiography; Electroencephalography; Female; Heart Rate; Male; Pentobarbital; Prazosin; Rabbits | 1988 |
A comparison of adrenergic receptors of rat ascites hepatoma AH130 cells with those of normal rat hepatocytes.
Topics: Animals; Clonidine; Female; Iodocyanopindolol; Liver; Liver Neoplasms, Experimental; Pindolol; Prazosin; Rats; Receptors, Adrenergic | 1988 |
Pharmacological nature of newer imidazoli(di)nes on rat anococcygeus muscle.
Topics: Animals; Clonidine; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1988 |
Evidence for a spinal site of action of clonidine on somatic and viscerosomatic reflex activity evoked on the pudendal nerve in cats.
Topics: Action Potentials; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Female; Male; Prazosin; Reflex; Spinal Cord; Urethra; Urinary Bladder; Yohimbine | 1988 |
Prazosin produces a sustained and reflex-mediated increase in renal sympathetic nerve activity in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Female; Heart Rate; Infusions, Intra-Arterial; Kidney; Male; Neurons; Piperoxan; Prazosin; Pressoreceptors; Reflex; Sympathetic Nervous System; Vertebral Artery | 1988 |
Age-related variation of EEG responses to clonidine, prazosin and yohimbine in rats.
Topics: Aging; Animals; Brain; Clonidine; Electroencephalography; Electrophysiology; Prazosin; Rats; Yohimbine | 1987 |
Central action of the antidepressant drug pirlindole.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Carbazoles; Cerebral Cortex; Clonidine; Dihydroalprenolol; Levodopa; Male; Mice; Norepinephrine; Prazosin; Rats; Reserpine; Serotonin | 1986 |
Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department.
Topics: Administration, Oral; Antihypertensive Agents; Captopril; Clonidine; Drug Administration Schedule; Emergency Service, Hospital; Hemodynamics; Humans; Hypertension; Labetalol; Minoxidil; Nifedipine; Prazosin | 1986 |
Characterization of the central sympathoinhibitory action of ketanserin.
Topics: Animals; Blood Pressure; Cats; Clonidine; Electrophysiology; Ergolines; Heart Rate; Ketanserin; Prazosin; Sympathetic Nervous System | 1987 |
Effects of splanchnic nerve stimulation and of clonidine on gastric and duodenal HCO3- secretion in the anaesthetized cat.
Topics: Animals; Bicarbonates; Cats; Clonidine; Duodenum; Electric Stimulation; Female; Gastric Acid; Gastrointestinal Motility; Intestinal Secretions; Male; Prazosin; Splanchnic Nerves; Vagus Nerve; Yohimbine | 1987 |
[Effects of clonidine on the levels of cyclic nucleotides in rat brain regions: the change in cyclic nucleotides after clonidine alone or in combination with alpha-antagonists].
Topics: Animals; Blood Pressure; Brain Chemistry; Clonidine; Drug Interactions; Heart Rate; Male; Nucleotides, Cyclic; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Adrenergic alpha 1 and alpha 2 binding sites are present in bovine retinal blood vessels.
Topics: Animals; Binding Sites; Cattle; Clonidine; Microscopy, Electron, Scanning; Prazosin; Retinal Vessels; Sympathomimetics | 1987 |
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred F344; Tremor; Yohimbine | 1987 |
Brain adrenoceptor binding sites in mice susceptible (DBA/2J) and resistant (C57 Bl/6) to audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Binding Sites; Brain; Clonidine; Dihydroalprenolol; Disease Susceptibility; Membranes; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Prazosin; Receptors, Adrenergic; Seizures; Tritium | 1986 |
Cardiovascular effects of perfusion of the rostral rat hypothalamus with clonidine: differential interactions with prazosin and yohimbine.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemodynamics; Hypothalamus; Male; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Neuropharmacological profile of a new series of dopamine agonists: N-n-propyl-hexahydronaphthoxazines.
Topics: 4-Butyrolactone; Animals; Binding, Competitive; Brain; Clonidine; Corpus Striatum; In Vitro Techniques; Male; Membranes; Motor Activity; Naphthalenes; Oxazines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Reserpine; Stereotyped Behavior | 1986 |
Evidence that endogenous catecholamines can regulate acetylcholine release in a sympathetic ganglion.
Topics: Acetylcholine; Animals; Cats; Clonidine; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Norepinephrine; Phentolamine; Prazosin; Yohimbine | 1986 |
The significance of adrenaline-induced potentiation of electrogenic sodium pumping in bullfrog sympathetic ganglia.
Topics: Animals; Clonidine; Epinephrine; Ganglia, Sympathetic; Kinetics; Methoxamine; Ouabain; Potassium; Prazosin; Propranolol; Rana catesbeiana; Sodium; Sucrose; Yohimbine | 1985 |
Role of endothelium in the contractions induced by norepinephrine and clonidine in rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Clonidine; Endothelium; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Potassium; Prazosin; Quinacrine; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Vasodilator Agents; Yohimbine | 1985 |
Desipramine binding: relationship to central and sympathetic noradrenergic activity.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dextroamphetamine; Heart; Hydroxydopamines; Isoproterenol; Male; Muscles; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synapses | 1985 |
Effect of urapidil, clonidine, and prazosin on sympathetic tone in conscious rats.
Topics: Animals; Blood Pressure; Clonidine; Electrodes; Heart Rate; Piperazines; Prazosin; Pressoreceptors; Rats; Rats, Inbred SHR; Splanchnic Nerves; Sympathetic Nervous System | 1986 |
Effects of urapidil, clonidine, prazosin and propranolol on autonomic nerve activity, blood pressure and heart rate in anaesthetized rats and cats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Neurons; Piperazines; Prazosin; Propranolol; Quinazolines; Rats; Rats, Inbred Strains; Species Specificity; Splanchnic Nerves; Sympathetic Nervous System; Vagus Nerve | 1985 |
Ventricular tachycardia induced by clonidine withdrawal.
Topics: Blood Pressure; Clonidine; Electrocardiography; Female; Humans; Middle Aged; Phentolamine; Prazosin; Substance Withdrawal Syndrome; Tachycardia | 1985 |
Cardiovascular effects and interaction with adrenoceptors of urapidil.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cats; Clonidine; Decerebrate State; Female; Hemodynamics; Hexobarbital; In Vitro Techniques; Infusions, Parenteral; Male; Membranes; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Piperazines; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic | 1985 |
The functional importance of cerebral noradrenergic processes for the activating action of nootropic drugs in the behavioural despair test in mice.
Topics: Animals; Behavior, Animal; Brain; Clonidine; Dextroamphetamine; Immobilization; Male; Mice; Norepinephrine; Prazosin; Yohimbine | 1985 |
Characterization of postjunctional adrenoceptor subtypes in isolated rat myocardial cells in culture.
Topics: Action Potentials; Albuterol; Animals; Atenolol; Cells, Cultured; Clonidine; Heart; Heart Rate; Isoproterenol; Methoxamine; Myocardium; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic | 1985 |
Interaction between clonidine and alpha blockers.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Prazosin | 1985 |
Sympathetic nervous system in essential hypertension and antihypertensive response to alpha 2-adrenoceptor stimulation.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Clonidine; Humans; Hypertension; Norepinephrine; Prazosin; Regional Blood Flow; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs: comparison of phenylephrine, clonidine, and guanabenz.
Topics: Animals; Calcium; Clonidine; Denervation; Dogs; Drug Interactions; Female; Guanabenz; Guanidines; Kidney; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Alpha-2 adrenoceptors modulate [3H]dopamine release from rabbit retina.
Topics: Animals; Calcium; Clonidine; Dopamine; Electric Stimulation; Epinephrine; Nomifensine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Retina; Yohimbine | 1984 |
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.
Topics: Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imidazoles; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Tyramine; Yohimbine | 1984 |
Presence of presynaptic inhibitory alpha 1-adrenoceptors in the cardiac sympathetic nerves of the dog: effects of prazosin and yohimbine on sympathetic neurotransmission to the heart.
Topics: Animals; Clonidine; Dogs; Female; Heart Rate; Male; Methoxamine; Myocardium; Norepinephrine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Stellate Ganglion; Sympathetic Nervous System; Synaptic Transmission; Tachycardia; Yohimbine | 1984 |
Comparative effects of urapidil, prazosin, and clonidine on ligand binding to central nervous system receptors, arterial pressure, and heart rate in experimental animals.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Piperazines; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Muscarinic | 1984 |
Isolation and partial purification of a clonidine-displacing endogenous brain substance.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cattle; Chromatography; Clonidine; Electrophoresis, Agar Gel; Erythrocytes; Humans; Imidazoline Receptors; In Vitro Techniques; Iodocyanopindolol; Molecular Weight; Pindolol; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Turkeys; Yohimbine | 1984 |
Norepinephrine stimulation of phosphoinositide hydrolysis in rat cerebral cortex is associated with the alpha1-adrenoceptor.
Topics: Animals; Cerebral Cortex; Clonidine; Hydrolysis; Isoproterenol; Male; Norepinephrine; Phenylephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Inhibitory presynaptic effect of noradrenaline on the hypogastric ganglion of the guinea pig.
Topics: Acetylcholine; Animals; Clonidine; Electric Stimulation; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Neurosecretory Systems; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Synaptic Transmission; Vas Deferens; Yohimbine | 1984 |
[Preliminary studies of the adrenergic receptors in the human right atrium].
Topics: Clonidine; Dihydroalprenolol; Heart Atria; Humans; In Vitro Techniques; Myocardium; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tritium | 1984 |
Age and day-night changes in clonidine-induced analgesia in mice.
Topics: Age Factors; Analgesia; Animals; Circadian Rhythm; Clonidine; Male; Mice; Mice, Inbred Strains; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Yohimbine | 1984 |
Nifedipine and alpha adrenoceptors in rat aorta. II. Role of extracellular calcium in enhanced alpha-2 adrenoceptor-mediated contraction in diabetes.
Topics: Animals; Aorta; Calcium; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Adrenergic receptors in Parkinson's disease.
Topics: Clonidine; Dihydroalprenolol; Frontal Lobe; Humans; Locus Coeruleus; Neural Pathways; Norepinephrine; Parkinson Disease; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1984 |
Changes in brain alpha-adrenoceptors with increasing age in rabbits.
Topics: Aging; Animals; Blood Pressure; Brain; Clonidine; Male; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1984 |
An attempt to identify alpha-adrenoceptors in the human placenta.
Topics: Binding Sites; Clonidine; Dihydroergotoxine; Female; Humans; Kinetics; Placenta; Prazosin; Pregnancy; Receptors, Adrenergic, alpha; Time Factors | 1984 |
alpha 2 and alpha 1-Adrenoceptors mediate opposing actions on parasympathetic neurons.
Topics: Animals; Cats; Clonidine; Drug Interactions; Ganglia, Parasympathetic; In Vitro Techniques; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1984 |
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
Topics: Animals; Azepines; Binding, Competitive; Blood Pressure; Clonidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Myocardium; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs.
Topics: Animals; Calcium; Clonidine; Dogs; Dose-Response Relationship, Drug; Guanabenz; Kidney; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Errors in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; Patient Compliance; Prazosin | 1980 |
Adverse drug reactions to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Physician-Patient Relations; Prazosin; Sodium Chloride Symporter Inhibitors | 1980 |
Antihypertensive drugs that alter adrenergic function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System | 1980 |
What patients with hypertension should know about their medication.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Patient Education as Topic; Prazosin; Sympatholytics | 1980 |
Multiple central WB-4101 binding sites and the selectivity of prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brain; Cattle; Clonidine; Dioxanes; Dioxins; In Vitro Techniques; Kinetics; Membranes; Norepinephrine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha | 1980 |
Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Clonidine; Doxazosin; Heart Rate; Hemodynamics; Hexobarbital; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Quinazolines; Rats | 1980 |
Pre- and postsynaptic alpha-adrenoceptor antagonists: differentiated cardiovascular effects in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Pentobarbital; Phenoxybenzamine; Phentolamine; Prazosin; Premedication; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Involvement of central alpha 2-adrenoceptors in the mediation of clonidine-induced hypotension in the cat.
Topics: Animals; Blood Pressure; Cats; Clonidine; Female; Hypotension; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Antihypertensive drugs: proposed sites and mechanisms of action.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Denervation; Dogs; Heart Rate; Methysergide; Moxisylyte; Phentolamine; Piperazines; Prazosin; Uracil | 1981 |
Pre- and postsynaptic alpha-adrenoceptor antagonism by neuroleptics in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Blood Pressure; Clonidine; Cocaine; Heart Rate; Phentolamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1981 |
Evidence for a central depressor action of postsynaptic alpha 1-adrenergic receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Depression, Chemical; Dioxanes; Hemodynamics; Phentolamine; Piperoxan; Prazosin; Pressoreceptors; Receptors, Adrenergic; Sympathetic Nervous System | 1981 |
Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Weight; Clonidine; Diastole; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Minoxidil; Norepinephrine; Posture; Prazosin; Propranolol; Quinazolines; Renin; Systole | 1981 |
[3H]prazosin and [3H]clonidine binding to alpha-adrenoceptors in membranes prepared from regions of rat kidney.
Topics: Animals; Binding Sites; Clonidine; In Vitro Techniques; Kidney; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Species Specificity; Tritium | 1981 |
Comparison of pre- and postsynaptic alpha-adrenoceptor blocking effects of E-643 in the isolated vas deferens of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1981 |
Clonidine-induced potentiation of reflex vagal bradycardia in anaesthetized cats.
Topics: Animals; Cats; Cisterna Magna; Clonidine; Drug Interactions; Female; Heart Rate; Injections; Male; Prazosin; Receptors, Adrenergic, alpha; Reflex; Vagus Nerve; Yohimbine | 1982 |
[The present status of treatment of hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Captopril; Clonidine; Humans; Hypertension; Nifedipine; Prazosin | 1981 |
Characterization of neurotransmitter receptors in the rat hippocampal formation.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dihydroalprenolol; Flunitrazepam; Hippocampus; Kinetics; Male; Naloxone; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter | 1982 |
Lowering of blood pressure in hypertensive rats by SKF 64139 and SKF 72223.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hypertension; Isoquinolines; Male; Phenylethanolamine N-Methyltransferase; Prazosin; Premedication; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines | 1982 |
The alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood-Brain Barrier; Cats; Clonidine; Female; Hemodynamics; Hypertension, Renal; Injections, Intraventricular; Male; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine].
Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Decerebrate State; Guanfacine; Guanidines; Heart Rate; Male; Phentolamine; Phenylacetates; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: evidence for antidopaminergic properties of some alpha antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Dopamine; Female; Haloperidol; Homovanillic Acid; Male; Prazosin; Rats; Spiperone; Synaptic Transmission; Yohimbine | 1982 |
Demonstration of alpha-2-adrenoceptor antagonist (yohimbine-like) activity of cirazoline using a hamster fat cell preparation.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Glycerol; Imidazoles; In Vitro Techniques; Lipolysis; Male; Prazosin; Yohimbine | 1982 |
[The use of vasodilator agents in the therapy of chronic cardiac insufficiency].
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Captopril; Clonidine; Diuretics; Heart Failure; Humans; Methyldopa; Nitrates; Nitroprusside; Prazosin; Vasodilator Agents | 1982 |
Peripheral alpha 1- and alpha 2-adrenoreceptor mechanisms in blood pressure control.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Blood Pressure; Clonidine; Dioxins; Guanabenz; Idazoxan; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pressoreceptors; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses; Vascular Resistance | 1983 |
Reversal of the central hypotensive effect of clonidine by intracisternal curare-like agents.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cisterna Magna; Clonidine; Decamethonium Compounds; Dogs; Female; Gallamine Triethiodide; Hypertension; Male; Neuromuscular Nondepolarizing Agents; Pancuronium; Prazosin; Pressoreceptors; Receptors, Adrenergic, alpha; Stimulation, Chemical; Tubocurarine; Yohimbine | 1983 |
In vitro studies with (imidazolinyl-2)-2-benzodioxane-1-4 ((+/-)-170 150), a new potent alpha 2-adrenoceptor blocking agent.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Clonidine; Dioxins; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Hot Temperature; Hydroxydopamines; Injections, Spinal; Male; Methoxamine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1983 |
CGS 7525A, a new, centrally active alpha 2 adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Clonidine; Male; Mesencephalon; Mianserin; Norepinephrine; Prazosin; Quinones; Rats; Rats, Inbred Strains; Spiperone; Yohimbine | 1983 |
Hypotensive and alpha-adrenergic activities of 2-(2,3,6-trichlorophenylimino) and 2-(2,3-dichloro-6-methylphenylimino) imidazolidine, two potent derivatives of clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hexobarbital; Hypnotics and Sedatives; Imidazolidines; Male; Mice; Prazosin; Rats; Rats, Inbred Strains; Sleep; Structure-Activity Relationship | 1983 |
Selectivity of benzodioxane alpha-adrenoceptor antagonists for alpha 1- and alpha 2-adrenoceptors determined by binding affinity.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Clonidine; In Vitro Techniques; Male; Membranes; Piperidines; Piperoxan; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Role of the autonomic nervous system in the release of rat submandibular gland kallikrein into the circulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Autonomic Nervous System; Carotid Artery Diseases; Clonidine; Electric Stimulation; Kallikreins; Male; Prazosin; Rats; Rats, Inbred Strains; Submandibular Gland; Yohimbine | 1983 |
The cardiovascular effects of MPV 295 [4(5)-2-(2,6-dimethylphenyl)ethylimidazole], a new antihypertensive agent with alpha 2-adrenoceptor agonistic properties.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Cats; Clonidine; Heart Rate; Imidazoles; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Affinities for alpha- and beta-adrenoceptor subtypes of YM-09538, a new combined alpha- and beta-adrenoceptor antagonist, by radioligand binding assay.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Brain; Clonidine; Dihydroalprenolol; Ethanolamines; Guinea Pigs; In Vitro Techniques; Lung; Male; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1983 |
Alpha-1 adrenoceptors and calcium in isolated canine coronary arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Clonidine; Coronary Vessels; Dogs; Female; Imidazoles; Male; Methoxamine; Muscle Contraction; Norepinephrine; Phenylephrine; Prazosin; Secologanin Tryptamine Alkaloids; Yohimbine | 1983 |
Effects of clonidine on operant behavior and electric shock titration in the squirrel monkey: effects of alpha 2-adrenoreceptor antagonism.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Male; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Saimiri; Tolazoline; Yohimbine | 1983 |
Antihypertensives and their impact on renal function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Captopril; Central Nervous System; Clonidine; Glomerular Filtration Rate; Humans; Kidney; Labetalol; Methyldopa; Prazosin; Renal Circulation; Vasodilator Agents | 1983 |
alpha-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Imidazoles; Male; Phentolamine; Prazosin; Rats; Vas Deferens | 1983 |
Characterization of postsynaptic alpha-adrenoceptors in rat aortic strips and portal veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Female; Male; Muscle, Smooth, Vascular; Nordefrin; Oxymetazoline; Phenethylamines; Portal Vein; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Yohimbine | 1983 |
A regional difference in the distribution of postsynaptic alpha-adrenoceptor subtypes in canine veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Epinephrine; Female; Guanethidine; Heart Rate; Male; Nordefrin; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spinal Nerves; Yohimbine | 1983 |
Antihypertensive activity and interaction with alpha-adrenoceptors of tibalosine ([1-(2, 3-dihydro-5-benzo-(b)-thienyl)-2-(4-phenyl-butylamino)-1-propanol], CP 804 S) in rat and cat preparations.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; Brain; Cats; Clonidine; Female; Heart Rate; Injections, Intraventricular; Male; Membranes; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Vasopressins | 1983 |
Sexual dysfunction due to antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydralazine; Male; Methyldopa; Prazosin; Propranolol; Reserpine; Sex; Sexual Dysfunction, Physiological; Sodium Chloride Symporter Inhibitors; Spironolactone | 1984 |
Office management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Captopril; Clonidine; Diuretics; Guanabenz; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors | 1984 |
alpha- 1 and alpha-2 type adrenoceptors involved in the inhibitory effect of splanchnic nerves on parasympathetically stimulated gastric acid secretion in rats.
Topics: Animals; Bethanechol; Bethanechol Compounds; Clonidine; Electric Stimulation; Gastric Acid; Male; Parasympathetic Nervous System; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Splanchnic Nerves; Vagus Nerve; Yohimbine | 1984 |
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride | 1984 |
Pharmacological characterization of postjunctional alpha-adrenoceptors in isolated human omental arteries and veins.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Clonidine; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Omentum; Oxymetazoline; Phenylephrine; Prazosin; Veins; Yohimbine | 1984 |
Effect of clonidine at steady state on blood pressure in spontaneously hypertensive rats. Interaction of various alpha-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Benzimidazoles; Blood Pressure; Clonidine; Dioxanes; Drug Interactions; Hypertension; Male; Phentolamine; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1984 |
Assessment of alpha-adrenergic receptor subtypes in isolated rat aortic segments.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Antihypertensive activity of tibalosine (CP 804 S) in the rat. Possible involvement of a central alpha 1-adrenergic receptor blockade.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Desoxycorticosterone; Female; Heart Rate; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Naloxone; Prazosin; Propanolamines; Rats; Rats, Inbred Strains | 1984 |
The actions of cirazoline on the rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens | 1984 |
Duration of tonic immobility in chickens as a function of alpha-adrenergic receptor stimulation and blockade.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Chickens; Clonidine; Guanfacine; Guanidines; Methoxamine; Naphazoline; Phenylacetates; Phenylephrine; Prazosin; Restraint, Physical; Time Factors; Yohimbine | 1984 |
Effects of clonidine and some alpha-adrenergic antagonists alone and in combination on schedule-controlled behavior in pigeons and mice.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Columbidae; Conditioning, Operant; Drug Interactions; Male; Mice; Prazosin; Reinforcement Schedule; Species Specificity; Yohimbine | 1984 |
Effects of methoxamine, and alpha-1 adrenoceptor agonist, and prazosin, an alpha-1 antagonist, on the stages of the sleep-waking cycle in the cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cats; Clonidine; Dose-Response Relationship, Drug; Male; Methoxamine; Prazosin; Quinazolines; Sleep; Sleep Stages; Sleep, REM; Wakefulness | 1984 |
Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Naphthalenes; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Tetrahydronaphthalenes; Vasoconstriction | 1984 |
Alpha 1- and alpha 2-adrenoceptors in the smooth muscle of isolated rabbit urinary bladder and urethra.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Urethra; Urinary Bladder; Yohimbine | 1984 |
The hydroxy-hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists.
Topics: 4-Butyrolactone; Animals; Binding, Competitive; Brain Chemistry; Chemical Phenomena; Chemistry; Clonidine; Dopamine; Ergolines; Homovanillic Acid; Humans; In Vitro Techniques; Mianserin; Oxazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Serotonin; Stereotyped Behavior | 1984 |
Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Amobarbital; Animals; Clonidine; Diazepam; Exploratory Behavior; Fear; Male; Models, Psychological; Picrotoxin; Prazosin; Rats | 1984 |
Effect of alpha adrenergic agonists and blockers on Purkinje fiber transmembrane potentials and automaticity in the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart Conduction System; In Vitro Techniques; Membrane Potentials; Phenylephrine; Prazosin; Purkinje Fibers; Yohimbine | 1984 |
Reduced alpha 2-adrenoceptor binding in lower brainstem of stroke-prone spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brain Stem; Cerebrovascular Disorders; Clonidine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
The selectivity of DG-5128 as an alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains | 1984 |
Neuropsychiatric manifestations of antihypertensive medications.
Topics: Adrenergic beta-Antagonists; Affective Symptoms; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors | 1983 |
Effect of neonatal 6-hydroxydopamine treatment on alpha 1- and alpha 2-adrenoceptors in rat cerebral cortex.
Topics: Aging; Animals; Animals, Newborn; Brain; Clonidine; Female; Hydroxydopamines; Kinetics; Prazosin; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Alpha 1-adrenergic stimulation of hamster brown adipocyte respiration.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue, Brown; Animals; Clonidine; Cricetinae; Isoproterenol; Kinetics; Male; Mesocricetus; Methoxamine; Norepinephrine; Oxygen Consumption; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha | 1983 |
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine | 1984 |
Effects of thymoxamine and its metabolites on clonidine-induced hypotension and bradycardia in rats.
Topics: Anesthesia; Animals; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypotension; Male; Moxisylyte; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Spinal Cord | 1982 |
Ontogeny of alpha 1 and alpha 2-adrenoceptors in rat brain.
Topics: Aging; Animals; Brain; Clonidine; Female; Male; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Characterization of alpha-adrenoceptors in rat and guinea pig tissues using radiolabeled agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Clonidine; Dioxanes; Dioxins; Guinea Pigs; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Postsynaptic alpha 1- and alpha 2-adrenoceptors in the circulatory system of the pithed rat: selective stimulation of the alpha 2-type by B-HT 933.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Oxazoles; Phentolamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Vasomotor System; Yohimbine | 1980 |
3H-Prazosin binds specifically to 'alpha 1'-adrenoceptors in rat brain.
Topics: Animals; Brain; Clonidine; In Vitro Techniques; Kinetics; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Sodium ions increase the affinity of clonidine for alpha 1-adrenoceptors in rat brain.
Topics: Animals; Brain; Clonidine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium | 1980 |
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Antagonism; Female; Methyldopa; Motor Activity; Nordefrin; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
Investigation into different types of post- and presynaptic alpha-adrenoceptors at cardiovascular sites in rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Clonidine; Electric Stimulation; Heart Rate; Male; Methoxamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1980 |
Calcium- and potassium-channel blockers interact with alpha-adrenoceptors.
Topics: Aminopyridines; Animals; Brain; Calcium; Clonidine; Gallopamil; Guanidines; Ion Channels; Myocardium; Potassium; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tetraethylammonium Compounds; Verapamil | 1980 |
Aspects of the pharmacology of prazosin.
Topics: Animals; Cats; Clonidine; Femoral Artery; Femoral Vein; In Vitro Techniques; Mesenteric Arteries; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Rabbits; Receptors, Adrenergic, alpha; Vasodilation; Yohimbine | 1980 |
Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain.
Topics: Aniline Compounds; Animals; Cerebral Cortex; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; In Vitro Techniques; Indoramin; Naphazoline; Oxazoles; Phenylacetates; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Thiophenes; Toluidines | 1980 |
Alpha 2 adrenoceptors in rat brain: the divalent cation site.
Topics: Animals; Brain; Cations, Divalent; Clonidine; Magnesium; Membranes; Prazosin; Protein Conformation; Protein Denaturation; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Temperature | 1980 |
Characterization and quantitation of alpha-adrenergic receptor subtypes in rat hypothalamus.
Topics: Animals; Binding Sites; Clonidine; Dihydroergotoxine; Female; Hypothalamus; Norepinephrine; Phentolamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
alpha 1- and alpha 2-adrenoceptors in rat cerebral cortex: effect of frontal lobotomy.
Topics: Animals; Binding Sites; Cerebral Cortex; Clonidine; Frontal Lobe; Male; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathectomy | 1981 |
[Importance of radioreceptor assays in determining the mechanism of action of hypotensive alpha-adrenergic compounds].
Topics: Animals; Antihypertensive Agents; Clonidine; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Involvement of alpha 1-adrenergic receptors in the inhibitory effect of catecholamines on the thyrotropin-induced release of thyroxine by the mouse thyroid.
Topics: Animals; Clonidine; Cyclic AMP; Kinetics; Male; Methoxamine; Mice; Mice, Inbred Strains; Norepinephrine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thyroid Gland; Thyrotropin; Thyroxine; Yohimbine | 1982 |
Functional characterization of postjunctional alpha-adrenoceptors in rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1981 |
Alpha-noradrenaline modulation of D,L-allylgycine seizures.
Topics: Allylglycine; Animals; Clonidine; Glycine; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Seizures; Yohimbine | 1981 |
Differential effects of pharmacological manipulations of central alpha 1- and alpha 2-adrenergic receptors on the secretion of thyrotropin and growth hormone in male rats.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Growth Hormone; Hypothalamus; Kinetics; Male; Methoxamine; Methoxyhydroxyphenylglycol; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Thyrotropin; Yohimbine | 1982 |
Clonidine inhibition of pancreatic secretion in rats: a possible central site of action.
Topics: Animals; Clonidine; Deoxyglucose; Gastric Juice; Male; Mianserin; Pancreas; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Anticonvulsant effects of clonidine mediated through central alpha2-adrenoceptors.
Topics: Animals; Anticonvulsants; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
alpha 2-Adrenergic receptor regulation of ion transport in rabbit ileum.
Topics: Animals; Biological Transport, Active; Clonidine; Epinephrine; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Methoxamine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Alpha-2 adrenergic antilipolytic effect in dog fat cells: incidence of obesity and adipose tissue localization.
Topics: Adipose Tissue; Animals; Clonidine; Dogs; Epinephrine; Isoproterenol; Lipolysis; Obesity; Prazosin; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Yohimbine | 1982 |
The relationship between alpha 2-adrenoceptor selectivity and anticonvulsant effect in a series of clonidine-like drugs.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Clonidine; Female; Male; Pentylenetetrazole; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Seizures | 1982 |
Measurement of alpha-adrenoceptor "turnover' using phenoxybenzamine.
Topics: Animals; Clonidine; Male; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Discriminative stimulus properties of the vasodilator, hydralazine: differential generalization with alpha 1 and alpha 2 adrenoreceptor drugs.
Topics: Animals; Blood Pressure; Clonidine; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Hydralazine; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Caffeine down-regulates beta adrenoreceptors in rat forebrain.
Topics: alpha-Methyltyrosine; Animals; Binding, Competitive; Brain; Caffeine; Clonidine; Dihydroalprenolol; Dopamine; Female; Methyltyrosines; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Synaptic Transmission | 1982 |
The effect of microelectrophoretically applied clonidine on single cerebral cortical neurones in the rat. Evidence for interaction with alpha 1-adrenoceptors.
Topics: Animals; Cerebral Cortex; Clonidine; Electrophoresis; In Vitro Techniques; Male; Neurons; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors | 1982 |
Demonstration of alpha 2-adrenergic receptors in rat pancreatic islets using radioligand binding (41498).
Topics: Animals; Clonidine; Epinephrine; Islets of Langerhans; Isoproterenol; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Interactions of leucine-enkephalin with alpha-adrenoceptors in the conscious dog.
Topics: Animals; Blood Pressure; Chemoreceptor Cells; Clonidine; Consciousness; Dogs; Enkephalin, Leucine; Heart Rate; Naloxone; Prazosin; Pressoreceptors; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1983 |
Locomotor activity of rats after stimulation of the nucleus locus coeruleus region or after lesion of the dorsal noradrenergic bundle: effects of clonidine, prazosin and yohimbine.
Topics: Animals; Brain Stem; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Exploratory Behavior; Hippocampus; Hydroxydopamines; Locus Coeruleus; Male; Motor Activity; Neural Pathways; Norepinephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1982 |
Piperazinylimidazo[1,2-a]pyrazines with selective affinity for in vitro alpha-adrenergic receptor subtypes.
Topics: Animals; Binding, Competitive; Cattle; Cerebral Cortex; Clonidine; Magnetic Resonance Spectroscopy; Prazosin; Pyrazines; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Alpha 2 adrenergic receptors are located prejunctionally in the Auerbach's plexus of the guinea pig small intestine: direct demonstration by radioligand binding.
Topics: Animals; Clonidine; Guinea Pigs; Intestine, Small; Male; Myenteric Plexus; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tritium | 1982 |
Effects of alpha 1 and alpha 2 activation of adrenergic receptors on aqueous humor dynamics.
Topics: Animals; Aqueous Humor; Cats; Clonidine; Intraocular Pressure; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Turnover in vivo of alpha 1-adrenergic receptors in rat submaxillary glands.
Topics: Animals; Clonidine; Cycloheximide; Dihydroalprenolol; Male; Phenoxybenzamine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Submandibular Gland | 1983 |
Hypotensive activity of tetrandrine in rats. Investigation into its mode of action.
Topics: Alkaloids; Anesthesia; Animals; Antihypertensive Agents; Azepines; Benzylisoquinolines; Blood Pressure; Brain; Clonidine; Heart Rate; Hypertension; Male; Methoxamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasopressins | 1983 |
alpha2-Adrenergic stimulation enhances growth hormone secretion in the dog: a presynaptic mechanism?
Topics: Animals; Clonidine; Dogs; Female; Growth Hormone; Kinetics; Male; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Synapses; Yohimbine | 1983 |
Effect of glucocorticoids on alpha-2 adrenoceptors in vas deferens of reserpinized rat in organ culture.
Topics: Animals; Clonidine; Dexamethasone; Glucocorticoids; Hydrocortisone; Kinetics; Male; Organ Culture Techniques; Prazosin; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Yohimbine | 1983 |
Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. III. Comparison of central and peripheral alpha-1 and alpha-2 adrenoceptors.
Topics: Animals; Clonidine; Imidazoles; Male; Mathematics; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Alpha adrenergic receptor subtype associated with receptor binding, Ca++ influx, Ca++ release and contractile events in the rabbit aorta.
Topics: Animals; Aorta; Calcium; Clonidine; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Alpha 2 adrenoceptor-mediated vasoconstriction of arteries.
Topics: Adult; Brachial Artery; Clonidine; Drug Interactions; Female; Hemodynamics; Humans; Infusions, Intra-Arterial; Male; Phentolamine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Vasoconstriction | 1983 |
Modulation of cortical acetylcholine and gamma-aminobutyric acid release in freely moving guinea pigs: effects of clonidine and other adrenergic drugs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Sympathomimetics; Yohimbine | 1983 |
Time course of changes in [3H]prazosin binding after catecholaminergic denervation by 6-hydroxydopamine in rat cerebral cortex. Inhibitory effects of ascorbic acid on the alpha 1-adrenoceptor.
Topics: Animals; Ascorbic Acid; Brain; Catecholamines; Clonidine; Female; Hydroxydopamines; Kinetics; Male; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy, Chemical; Time Factors | 1983 |
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages | 1983 |
Study of two alkylating derivatives: the p-isothiocyanato- and the p-methylisothiocyanato-clonidine.
Topics: Alkylating Agents; Animals; Aorta; Brain; Clonidine; In Vitro Techniques; Male; Membranes; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Different modes of action of clonidine on isolated canine veins.
Topics: Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Portal Vein; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Vasoconstriction; Veins | 1983 |
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension.
Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Vasodilator Agents | 1984 |
Alpha-adrenoceptor number and function in rat cortex after ethanol and immobilization stress.
Topics: Animals; Cerebral Cortex; Clonidine; Ethanol; Humans; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stress, Psychological | 1983 |
[Characteristics of alpha adrenoceptors of lymphatics and their physiological significance].
Topics: Animals; Binding, Competitive; Cattle; Clonidine; In Vitro Techniques; Lymphatic System; Mesentery; Muscle Contraction; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Interaction between 2-chloroadenosine and alpha-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1984 |
Alpha-2 adrenergic receptors on neurones in the region of the lateral reticular nucleus of the rat.
Topics: Animals; Clonidine; Dioxins; Evoked Potentials; gamma-Aminobutyric Acid; Humans; Idazoxan; Medulla Oblongata; Neurons; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Reticular Formation; Synaptic Transmission | 1983 |
Presynaptic alpha-adrenoceptors: do exogenous and neuronally released noradrenaline act at different sites?
Topics: Animals; Clonidine; Dogs; Dopamine; Feedback; In Vitro Techniques; Nerve Endings; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sulpiride; Synaptic Transmission; Yohimbine | 1984 |
Differential blocking effects of prazosin and yohimbine on vasopressor responses to sympathetic nerve stimulation and intravenous norepinephrine in the pithed rat.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Male; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
Peroxidase secretion from rat lacrimal gland cells in vitro. I. Alpha-adrenergic stimulation in the absence of alpha-adrenoceptors.
Topics: Animals; Clonidine; In Vitro Techniques; Isoenzymes; Lacrimal Apparatus; Male; Peroxidase; Peroxidases; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympatholytics; Sympathomimetics | 1983 |
Functional characterization of the alpha adrenergic receptor modulating the hydroosmotic effect of vasopressin on the rabbit cortical collecting tubule.
Topics: Absorption; Animals; Arginine Vasopressin; Body Water; Cell Membrane Permeability; Clonidine; Female; Kidney Tubules; Kidney Tubules, Collecting; Norepinephrine; Osmosis; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Alpha-1 adrenoceptors mediate secretory responses to norepinephrine in innervated and denervated rat submaxillary glands.
Topics: Animals; Clonidine; Cocaine; Denervation; Female; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Submandibular Gland | 1984 |
Characterization of the alpha adrenoceptor-mediated effects and antihypertensive activity of ICI 106270: comparison with clonidine.
Topics: Animals; Antihypertensive Agents; Brain; Clonidine; Dose-Response Relationship, Drug; Guinea Pigs; Hypertension; Imidazoles; Male; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep | 1984 |
The binding of [3H]prazosin and [3H]clonidine to rat jejunal epithelial cell membranes.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Epithelium; Jejunum; Kinetics; Male; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Topics: Adult; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Doxazosin; Female; Guanfacine; Guanidines; Heart Rate; Humans; Male; Methoxamine; Muscle, Smooth, Vascular; Phenylacetates; Prazosin; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1984 |
Predominance of alpha 2-adrenoceptors in porcine thyroid: biochemical and pharmacological correlations.
Topics: Animals; Bacterial Toxins; Clonidine; Cyclic AMP; Kinetics; Norepinephrine; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Swine; Thyroid Gland; Thyrotropin; Thyroxine; Virulence Factors, Bordetella; Yohimbine | 1984 |
Inhibitory action of the alpha 1-adrenergic receptor on growth hormone secretion in the dog.
Topics: Animals; Arginine; Clonidine; Dogs; Female; Growth Hormone; Kinetics; Male; Methoxamine; Prazosin; Receptors, Adrenergic, beta | 1984 |
Pharmacological characterization of the postsynaptic alpha adrenoceptors in vascular smooth muscle from canine and rat mesenteric vascular beds.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Hydroxydopamines; Muscle, Smooth, Vascular; Naphazoline; Oxidopamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Splanchnic Circulation; Yohimbine | 1984 |
Identification of alpha-adrenergic receptor subtypes in the steer stalk-median eminence.
Topics: Animals; Binding, Competitive; Cattle; Clonidine; Dihydroergotoxine; Kinetics; Male; Median Eminence; Prazosin; Receptors, Adrenergic | 1984 |
Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats.
Topics: Animals; Clonidine; Hypertension; Male; Naphazoline; Pain; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
Blood pressure changes in spontaneously hypertensive rats correlate with aortic prostacyclin formation.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Dihydralazine; Epoprostenol; Hypertension; Male; Prazosin; Prostaglandins; Rats | 1983 |
The effects of clonidine, prazosin, and propranolol on short-term and long-term habituation of the acoustic startle response in rats.
Topics: Acoustic Stimulation; Animals; Antihypertensive Agents; Clonidine; Habituation, Psychophysiologic; Male; Prazosin; Propranolol; Rats; Reflex, Startle | 1984 |
Diazepam, alpha and beta neurotransmission modifying drugs and contrast media mortality in mice.
Topics: Animals; Clonidine; Diatrizoate; Diatrizoate Meglumine; Diazepam; Drug Interactions; Female; Lethal Dose 50; Male; Metoprolol; Mice; Phentolamine; Prazosin; Propranolol; Sympatholytics; Sympathomimetics | 1984 |
Alpha 1-noradrenergic regulation of hypothalamic progestin receptors and guinea pig lordosis behavior.
Topics: Animals; Brain Mapping; Clonidine; Estradiol; Female; Guinea Pigs; Hypothalamus; Norepinephrine; Phenoxybenzamine; Posture; Prazosin; Receptors, Progesterone; Sexual Behavior, Animal | 1984 |
Changes in clonidine effect on longitudinal muscle-myenteric plexus strip preparation by morphine treatments.
Topics: Animals; Clonidine; Guinea Pigs; Morphine; Muscle, Smooth; Myenteric Plexus; Naloxone; Prazosin; Yohimbine | 1983 |
Influence of alpha-methyldopa treatment on adrenergic receptor binding in rat forebrain.
Topics: Animals; Brain; Clonidine; Dihydroalprenolol; Male; Methyldopa; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Tritium | 1983 |
Clonidine and prazosin in the treatment of hypertensive outpatients--a preliminary study.
Topics: Adult; Ambulatory Care; Blood Pressure; Clonidine; Drug Therapy, Combination; Drug Tolerance; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines; Time Factors | 1983 |
Use of a cell harvester for the collection of tissue fragments in receptor binding assays.
Topics: Animals; Binding Sites; Brain; Cell Separation; Clonidine; Filtration; Flunitrazepam; Kinetics; Prazosin; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains | 1983 |
Differences between the prejunctional effects of phenylephrine and clonidine in guinea-pig isolated atria.
Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Sympathetic Nervous System; Yohimbine | 1984 |
Interaction of dihydroxy-2-aminotetralin derivatives at sites labelled with [3H]clonidine, [3H]prazosin and [3H]spiperone in rat brain membranes.
Topics: Animals; Binding Sites; Brain; Butyrophenones; Cell Membrane; Cerebral Cortex; Clonidine; Drug Interactions; Male; Naphthalenes; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spiperone; Tetrahydronaphthalenes | 1984 |
Induction of opposite response of hindlimb vasculature to adrenergic agents in hypothyroid rats.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Heart Rate; Hindlimb; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Papaverine; Prazosin; Rats; Rats, Inbred Strains; Regional Blood Flow; Sympathomimetics | 1984 |
Factors influencing the release of purines and norepinephrine in the rabbit portal vein.
Topics: Adrenergic Fibers; Animals; Clonidine; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Portal Vein; Prazosin; Purines; Rabbits; Yohimbine | 1982 |
Altered hindlimb extension in the rat after DSP-4: a useful marker of central noradrenergic depletion.
Topics: Amines; Animals; Behavior, Animal; Benzylamines; Brain; Clonidine; Drug Interactions; Hindlimb; Male; Neurotoxins; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Comparison of yohimbine, mianserin, chlorpromazine and prazosin as antagonists of the suppressant effect of clonidine on operant behavior.
Topics: Animals; Behavior, Animal; Chlorpromazine; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Mianserin; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
Hypertension in older patients: what drugs to use and when.
Topics: Aged; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hypertension; Hypotension, Orthostatic; Male; Methyldopa; Middle Aged; Prazosin; Propranolol; Reserpine; Systole | 1982 |
Effects of prazosin and piperoxan on central cardiovascular actions of St 91 in cats.
Topics: Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Piperidines; Piperoxan; Prazosin; Quinazolines; Vertebral Artery | 1982 |
Self-stimulation response decrement patterns differentiate clonidine, baclofen and dopamine antagonists from drugs causing performance deficit.
Topics: Animals; Baclofen; Clonidine; Conditioning, Operant; Dopamine Antagonists; Extinction, Psychological; Haloperidol; Male; Methocarbamol; Metoclopramide; Prazosin; Rats; Rats, Inbred F344; Receptors, Dopamine; Self Stimulation | 1982 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hydralazine; Hypotension; Male; Mecamylamine; Methyldopa; Minoxidil; Phentolamine; Posture; Prazosin; Propranolol; Rats; Reserpine; Sympathetic Nervous System | 1981 |
[Antihypertensive activity of minoxidil, hydralazine, prazosin, phentolamine and clonidine in spontaneously hypertensive rats. Comparison with therapeutic dosages].
Topics: Animals; Antihypertensive Agents; Clonidine; Hydralazine; Hypertension; Minoxidil; Phentolamine; Prazosin; Rats | 1981 |
Lack of antagonism in the antihypertensive effects of clonidine and prazosin in man.
Topics: Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines | 1981 |
Special considerations in treating hypertension in the elderly.
Topics: Aged; Clonidine; Diet, Sodium-Restricted; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyperglycemia; Hypertension; Hypokalemia; Male; Methyldopa; Minoxidil; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Uric Acid | 1981 |
Role of alpha 1 and alpha 2-adrenoceptors of the lateral hypothalamic area on urinary excretion caused by centrally administered angiotensin II.
Topics: Angiotensin II; Animals; Clonidine; Drug Interactions; Hypothalamus; Male; Potassium; Prazosin; Rats; Rats, Inbred Strains; Sodium; Urination; Yohimbine | 1995 |
Antihypertensive effects of AT-112, a newly synthesized quinazoline derivative, in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Clonidine; Endothelium, Vascular; Female; Hypertension; Male; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Serotonin; Vasodilation | 1995 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Pharmacological characterization of alpha 1-adrenoceptor subtypes in the human prostate: functional and binding studies.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; Male; Muscle Contraction; Muscles; Norepinephrine; Phenylephrine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha-1 | 1994 |
Effects of three alpha 2-adrenoceptor agonists, rilmenidine, UK 14304 and clonidine on bradykinin- and substance P-induced airway microvascular leakage in guinea-pigs.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Capillaries; Capillary Permeability; Clonidine; Dioxanes; Extravascular Lung Water; Guinea Pigs; Idazoxan; Oxazoles; Prazosin; Quinoxalines; Rilmenidine; Substance P; Trachea | 1995 |
Alpha-adrenoceptors and angiotensinogen gene expression in opossum kidney cells.
Topics: Adrenergic alpha-Agonists; Affinity Labels; Alkaloids; Angiotensinogen; Animals; Cells, Cultured; Clonidine; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Kidney Tubules; Opossums; Phenylephrine; Prazosin; Protein Kinase C; Receptors, Adrenergic, alpha; Staurosporine; Tetradecanoylphorbol Acetate; Yohimbine | 1995 |
Alpha-adrenergic pathways in the lateral hypothalamus are important for the dipsogenic effect of carbachol injected into the medial septal area.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drinking; Hypothalamic Area, Lateral; Male; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1995 |
Evidence for a functional alpha 1A- (alpha 1C-) adrenoceptor mediating contraction of the rat epididymal vas deferens and an alpha 1B-adrenoceptor mediating contraction of the rat spleen.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Cocaine; Epididymis; Estradiol; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Vasoconstrictor Agents | 1995 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Renal aging change of alpha 1-adrenoceptor in Wistar rats.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Autoradiography; Binding Sites; Clonidine; Kidney; Kinetics; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1995 |
Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action.
Topics: Adrenergic alpha-Antagonists; Calcium; Clonidine; Contraceptive Agents, Male; Cystamine; Humans; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Prazosin; Vas Deferens | 1995 |
Characterization of alpha 1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulation.
Topics: Adrenergic Antagonists; Animals; Clonidine; Electric Stimulation; Humans; Hyperplasia; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Yohimbine | 1995 |
KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; CHO Cells; Clonidine; Cloning, Molecular; Cricetinae; Humans; Indoles; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Tamsulosin | 1995 |
Correlations between the hypothalamic density of 3H-clonidine-binding sites and plasma testosterone levels in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Binding Sites; Clonidine; Dihydroalprenolol; Hypothalamus; Kinetics; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Prazosin; Prefrontal Cortex; Receptors, Adrenergic, alpha-2; Testosterone | 1995 |
Further evidence that the classical alpha 1A- and cloned alpha 1c-adrenoceptors are the same subtype.
Topics: Animals; Binding Sites; Cattle; Clonidine; HeLa Cells; Humans; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins | 1995 |
Increased pressure in venous sinusoids during decongestion of rat nasal mucosa induced by adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Volume; Clonidine; Extracellular Space; Female; Hemodynamics; Lasers; Nasal Decongestants; Nasal Mucosa; Norepinephrine; Paranasal Sinuses; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance; Veins; Yohimbine | 1993 |
[Alpha adrenergic mechanism on the reflex micturition in the male decerebrate dog].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Decerebrate State; Dogs; Male; Manometry; Midodrine; Prazosin; Reflex; Urethra; Urinary Bladder; Urination; Urodynamics; Yohimbine | 1993 |
Alpha 1-adrenoceptor subtypes and inositol phosphates production in heart ventricles of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Heart Ventricles; Hypertension; Inositol Phosphates; Male; Myocardium; Norepinephrine; Prazosin; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha | 1993 |
Localization of glutamatergic neurons in the dorsolateral pontine tegmentum projecting to the spinal cord of the cat with a proposed role of glutamate on lumbar motoneuron activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Glutamic Acid; Locus Coeruleus; Lumbosacral Region; Motor Neurons; Neurons; Peroneal Nerve; Prazosin; Spinal Cord | 1995 |
Adrenergic modulation of a spinal sympathetic reflex in the rat.
Topics: Animals; Brimonidine Tartrate; Clonidine; Male; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Spinal Cord; Sympathetic Nervous System | 1995 |
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Effects of alpha-adrenoceptor agonists and antagonists on metabolic rate in cattle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Basal Metabolism; Body Temperature; Brimonidine Tartrate; Cattle; Clonidine; Dioxanes; Female; Guanfacine; Heart Rate; Idazoxan; Male; Prazosin; Quinoxalines | 1995 |
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Computer Simulation; Hippocampus; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regression Analysis; Spiperone; Stereoisomerism; Sulfonamides | 1995 |
Pharmacological characterization of alpha 1-adrenoceptor subtypes in rat heart: a binding study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Binding, Competitive; Clonidine; Heart; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Myocardium; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1995 |
Attenuation of arteriolar alpha 2-adrenoceptor sensitivity during endotoxemia.
Topics: Animals; Arterioles; Clonidine; Dioxanes; Endotoxins; Escherichia coli; Idazoxan; Male; Muscles; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Shock, Septic; Vasoconstriction | 1994 |
Effects of alpha-2 adrenoceptor antagonists on rough-and-tumble play in juvenile rats: evidence for a site of action independent of non-adrenoceptor imidazoline binding sites.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Agonistic Behavior; Animals; Clonidine; Dioxanes; Female; Idazoxan; Imidazoline Receptors; Interpersonal Relations; Male; Prazosin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Drug | 1994 |
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra.
Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra | 1994 |
Functional identification of alpha 1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 1994 |
Interactions of chloroethylclonidine with rauwolscine- and prazosin-sensitive adrenoceptors in dog saphenous vein.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Clonidine; Dioxanes; Dogs; Extracellular Space; In Vitro Techniques; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Saphenous Vein; Yohimbine | 1994 |
Distribution and density of monoamine receptors in the primate visual cortex devoid of retinal input from early embryonic stages.
Topics: Animals; Anophthalmos; Benzazepines; Clonidine; Eye Enucleation; Gene Expression Regulation, Developmental; Gestational Age; Ketanserin; Macaca mulatta; Pindolol; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Visual Cortex; Visual Pathways | 1995 |
Effect of the centrally acting muscle relaxant tizanidine on spinal reflexes: involvement of descending noradrenergic systems.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Dioxanes; Hexamethonium Compounds; Idazoxan; Male; Muscle Relaxants, Central; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reflex; Reflex, Monosynaptic; Spinal Cord; Sympathetic Nervous System | 1993 |
Alpha 1-adrenoceptor subtype involved in the positive inotropic response to phenylephrine in rat atria.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
Clonidine and phenylephrine injected into the lateral preoptic area reduce water intake in dehydrated rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dehydration; Drinking Behavior; Injections; Male; Phenylephrine; Prazosin; Preoptic Area; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 1993 |
Chloroethylclonidine discriminates between alpha 1A- and alpha 1B-adrenoceptors in the presence of guanosine 5'-triphosphate in rabbit thoracic aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding Sites; Clonidine; Dioxanes; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1993 |
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine | 1993 |
Sympathetic transmission to the dilator muscle of the rat iris.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Iris; Membrane Potentials; Neuroeffector Junction; Norepinephrine; Parasympathetic Nervous System; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sympathetic Nervous System; Synaptic Transmission; Synaptic Vesicles; Yohimbine | 1993 |
Noradrenaline decreases transmission of NMDA- and non-NMDA-receptor mediated monosynaptic EPSPs in rat prefrontal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Antagonists; Afferent Pathways; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Methoxamine; Neurons; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Prefrontal Cortex; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
Characterization of alpha 1-adrenoceptor subtypes in prostate and prostatic urethra of rat, rabbit, dog and man.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Binding Sites; Clonidine; Dogs; Humans; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Species Specificity; Urethra | 1993 |
Effects of age on alpha 1-adrenoceptor subtypes in the heart ventricular muscle of the rat.
Topics: Adrenergic alpha-Antagonists; Aging; Alkylating Agents; Animals; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Myocardium; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1993 |
Identification of alpha 1-adrenoceptor subtypes in rat renal proximal tubules.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Kidney Tubules; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
An alpha-adrenoceptor-mediated mechanism of hypoactivity induced by beta-amyrin palmitate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apomorphine; Clonidine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Motor Activity; Oleanolic Acid; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Triterpenes; Yohimbine | 1993 |
Effects of WB4101 and chloroethylclonidine on the positive and negative inotropic actions of phenylephrine in rat cardiac muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Drug Antagonism; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1994 |
Is SDZ NVI-085 an alpha 1-adrenoceptor subtype-selective agonist?
Topics: Adrenergic alpha-Agonists; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cattle; Cell Line; Cerebral Cortex; Clonidine; In Vitro Techniques; Inositol Phosphates; Kidney; Norepinephrine; Oxazines; Prazosin; Rats; Receptors, Adrenergic, alpha; Spleen; Transfection | 1994 |
Selective enrichment with alpha 1A- and alpha 1B-adrenoceptor subtypes in rat brain cortical membranes.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Binding Sites; Cerebral Cortex; Clonidine; Cystamine; Dihydropyridines; Dioxanes; Phenoxybenzamine; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1994 |
Characterization of the hepatic alpha 1B-adrenoceptors of rats, mice and hamsters.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Clonidine; Cricetinae; Dihydropyridines; Liver; Male; Mesocricetus; Mice; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Species Specificity | 1994 |
Radioligand binding studies of alpha 1-adrenoceptor subtypes in rat heart.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cadmium; Cadmium Chloride; Calcium; Chlorides; Clonidine; Epinephrine; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Piperazines; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Investigation of alpha 1-adrenoceptor subtypes in canine aorta, using alkylating agents.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Aorta; Binding, Competitive; Clonidine; Dioxanes; Dogs; Female; In Vitro Techniques; Male; Mesenteric Veins; Muscle, Smooth, Vascular; Oxymetazoline; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1 | 1994 |
Alpha 1-adrenoceptor subtype(s) mediating noradrenaline-induced contractions of the guinea-pig aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Dioxanes; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Oxazines; Prazosin; Receptors, Adrenergic, alpha-1 | 1994 |
Accelerated resensitization of the D1 dopamine receptor-mediated response in cultured cortical and striatal neurons from the rat: respective role of alpha 1-adrenergic and N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Cyclic AMP; Dopamine; Down-Regulation; Glutamic Acid; Isoproterenol; Methoxamine; Neurons; Prazosin; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 1994 |
Strychnine-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipramine; Male; Mice; Pargyline; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Seizures; Strychnine | 1994 |
Role of lateral preoptic area alpha-1 and alpha-2 adrenoceptors in sleep-wakefulness and body temperature regulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Body Temperature Regulation; Circadian Rhythm; Clonidine; Electroencephalography; Electromyography; Electrooculography; Male; Methoxamine; Microinjections; Prazosin; Preoptic Area; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sleep; Time Factors; Wakefulness; Yohimbine | 1994 |
Comparative study on alpha 1-adrenoceptor antagonist binding in human prostate and aorta.
Topics: Adrenergic alpha-Antagonists; Aged; Aorta; Binding Sites; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Kinetics; Male; Middle Aged; Naphthalenes; Piperazines; Prazosin; Prostate; Sulfonamides; Tamsulosin | 1994 |
A heterogeneous population of alpha 1 adrenergic receptors mediates contraction of human corpus cavernosum smooth muscle to norepinephrine.
Topics: Alkylating Agents; Clonidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Penis; Prazosin; Receptors, Adrenergic, alpha-1 | 1995 |
Diaspirin cross-linked hemoglobin (DCLHB): involvement of adrenergic mechanisms in the pressor effect.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Aspirin; Blood Pressure; Blood Substitutes; Clonidine; Drug Interactions; Hemoglobins; Male; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1994 |
Effect of clonidine on induced cough and bronchoconstriction in guinea pigs and healthy humans.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adult; Airway Resistance; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Citrates; Citric Acid; Clonidine; Cough; Female; Guinea Pigs; Heart Rate; Humans; Male; Prazosin; Receptors, Adrenergic, alpha-2; Species Specificity; Yohimbine | 1994 |
Defective glucoregulation of brain alpha 2-adrenoceptors in obesity-prone rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Glucose; Brain; Clonidine; Diet; Disease Susceptibility; Male; Norepinephrine; Obesity; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tissue Distribution | 1993 |
Alpha 2-adrenergic, but not imidazole, agonists activate NaCl cotransport in rabbit tracheal epithelial cells.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Carrier Proteins; Cells, Cultured; Chloride-Bicarbonate Antiporters; Clonidine; Colforsin; Cyclic AMP; Drug Interactions; Epithelial Cells; Epithelium; Guanabenz; Imidazoles; Imidazoline Receptors; Iodine Radioisotopes; Isoproterenol; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Second Messenger Systems; Sodium Chloride Symporters; Symporters; Thromboxane-A Synthase; Trachea | 1993 |
Alpha 1b-adrenoceptor-mediated stimulation of Na-K pump current in adult rat ventricular myocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Male; Myocardium; Ouabain; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sodium-Potassium-Exchanging ATPase; Ventricular Function, Left | 1993 |
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Epinephrine; Heart Rate; Hyperglycemia; Idazoxan; Indoles; Male; Mice; Motor Activity; Norepinephrine; Peripheral Nerves; Prazosin; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction | 1993 |
Pharmacological characterization of two distinct alpha 1-adrenoceptor subtypes in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1993 |
Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Body Temperature; Clonidine; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Pain Measurement; Prazosin; Yohimbine | 1993 |
Evidence for the presence of noradrenergic neurons and their inhibitory action on luteinizing hormone-releasing hormone release in cultured fetal rat hypothalamic cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Cells, Cultured; Clonidine; Female; Fetus; Gonadotropin-Releasing Hormone; Hypothalamus; Methyltyrosines; Neurons; Phenylephrine; Prazosin; Pregnancy; Rats; Rats, Sprague-Dawley; Yohimbine | 1993 |
Effects of nicotine on brain stem mechanisms of cardiovascular control.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Heart Rate; Hexamethonium; Hexamethonium Compounds; Labetalol; Male; Nicotine; Physostigmine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1993 |
Effects of alpha-2-adrenoceptor agonists on induced diuresis in rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Diuresis; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Male; Prazosin; Rats; Rats, Sprague-Dawley | 1993 |
Alpha 1B-adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Cyclic AMP; Dioxanes; In Vitro Techniques; Liver; Male; Methoxamine; Norepinephrine; Pertussis Toxin; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella | 1993 |
Clonidine-induced place preference is mediated by alpha 2-adrenoceptors outside the locus coeruleus.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Conditioning, Psychological; Dextroamphetamine; Dioxanes; Drug Interactions; Idazoxan; Injections, Intraperitoneal; Locus Coeruleus; Male; Oxidopamine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Alpha-1 adrenoceptor subtypes in canine aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Binding Sites; Clonidine; Dogs; Oxathiins; Prazosin; Receptors, Adrenergic, alpha; Structure-Activity Relationship | 1993 |
Central alpha 2-adrenoceptor-mediated inhibition of gastric motility in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Stem; Clonidine; Gastrointestinal Motility; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Relation between alpha 1-adrenoceptor subtypes and noradrenaline-induced contraction in rat portal vein smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Horses; In Vitro Techniques; Isometric Contraction; Kinetics; Microsomes; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Rats; Receptors, Adrenergic, alpha-1 | 1993 |
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes | 1993 |
Alpha 1-adrenoceptors in the human prostatic urethra are different from those of the human peripheral arteries.
Topics: Arteries; Atropine; Clonidine; Dioxanes; Humans; Iliac Artery; Isometric Contraction; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Urethra; Yohimbine | 1993 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin | 1993 |
Influence of endogenous cholinergic tone and alpha-adrenergic pathways on growth hormone responses to His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 in the dog.
Topics: Animals; Atropine; Cholinergic Fibers; Clonidine; Dogs; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Hormones; Male; Methoxamine; Oligopeptides; Prazosin; Pyridostigmine Bromide; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1993 |
The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat.
Topics: Animals; Blood Pressure; Clonidine; Consciousness; Drug Resistance; Hemodynamics; Hindlimb; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sensitivity and Specificity; Vascular Resistance | 1993 |
Naloxone potentiation of novelty-induced hypoalgesia: characterization of the alpha-noradrenergic receptor subtype.
Topics: Animals; Clonidine; Drug Synergism; Habituation, Psychophysiologic; Male; Naloxone; Pain; Phentolamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Role of adrenoceptors in the proximal urethral function of female and male rabbits using an in vivo model of isovolumetric pressure generation.
Topics: Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Phenylephrine; Prazosin; Pressure; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urethra | 1993 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine | 1993 |
Influence of sex, age and adrenergic pathways on the growth hormone response to GHRP-6.
Topics: Adult; Age Factors; Child; Clonidine; Drug Interactions; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Hormones; Humans; Male; Menstrual Cycle; Oligopeptides; Prazosin; Propranolol; Sex Factors | 1993 |
Effects of noradrenaline on the firing rate of vestibular neurons.
Topics: Action Potentials; Animals; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Eye Movements; Iontophoresis; Isoproterenol; Male; Movement; Neurons; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Wistar; Vestibular Nuclei; Vestibule, Labyrinth; Yohimbine | 1993 |
Alpha 1B-adrenergic receptors in rat renal microvessels.
Topics: Affinity Labels; Alkylating Agents; Animals; Azides; Binding Sites; Blood Vessels; Clonidine; Male; Microcirculation; Prazosin; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Renal Circulation; RNA, Messenger | 1995 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Action of dexmedetomidine on rat locus coeruleus neurones: intracellular recording in vitro.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Barium Compounds; Cesium; Chlorides; Clonidine; Electrophysiology; Imidazoles; In Vitro Techniques; Locus Coeruleus; Male; Medetomidine; Membrane Potentials; Neurons; Oxymetazoline; Parasympathetic Fibers, Postganglionic; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Evidence for a 5-HT1D receptor-mediated hypothermic effect of the alpha 1-adrenoceptor agonist, SDZ NVI-085, in guinea-pigs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Bridged-Ring Compounds; Clonidine; Guinea Pigs; In Vitro Techniques; Male; Oxadiazoles; Oxazines; Piperazines; Prazosin; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Mechanisms involved in electrically-induced responses of rat seminal vesicles.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Clonidine; Electric Stimulation; Guanethidine; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Wistar; Seminal Vesicles; Vasoconstrictor Agents | 1995 |
Comparison of guinea-pig, bovine and rat alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Clonidine; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Species Specificity; Tritium | 1996 |
Is alpha-adrenoceptor blockade responsible for atropine flush?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Male; Phentolamine; Phenylephrine; Prazosin; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Skin; Thromboxane A2; Vasodilation | 1995 |
Hypothalamic alpha 2A-adrenoceptors stimulate growth hormone release in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Dioxanes; Growth Hormone-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Male; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Somatostatin | 1995 |
Influence of adrenoceptor agonists and antagonists on fluid secretion in small bowel obstruction.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Albuterol; Analysis of Variance; Animals; Body Water; Clonidine; Intestinal Obstruction; Intestine, Small; Jejunal Diseases; Male; Metoprolol; Phenylephrine; Prazosin; Prenalterol; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arginine; Capsaicin; Clonidine; Male; Mice; Nitroarginine; Pain; Phenylephrine; Plant Extracts; Prazosin; Yohimbine | 1995 |
Central catecholaminergic neurons are involved in expression of the 10-Hz rhythm in SND.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Brain; Brain Stem; Cats; Clonidine; Electrophysiology; Epinephrine; Injections, Intravenous; Microinjections; Neurons; Norepinephrine; Oscillometry; Periodicity; Prazosin; Raphe Nuclei; Sympathetic Nervous System | 1996 |
A comparative study of the reversal by different alpha 2-adrenoceptor antagonists of the central sympatho-inhibitory effect of clonidine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hexamethonium; Imidazoles; Kidney; Male; Prazosin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1996 |
Contribution of the sympathetic nervous system to hypertensive response to insulin excess in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertension; Insulin; Male; Prazosin; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 1996 |
Effects of St-587 and prazosin on water maze and passive avoidance performance of scopolamine-treated rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Clonidine; Male; Maze Learning; Memory; Muscarinic Antagonists; Prazosin; Rats; Rats, Wistar; Scopolamine | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
alpha-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Prazosin; Receptors, Opioid; Yohimbine | 1996 |
Alpha 1-adrenoceptor subtype distribution and the coupling to phosphoinositide hydrolysis in rat and rabbit ventricular myocardium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Heart Ventricles; Hydrolysis; Kinetics; Lithium Chloride; Male; Myocardium; Phosphatidylinositols; Prazosin; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tritium | 1996 |
Clonidine-induced increase in osmolar clearance and free water clearance via activation of two distinct alpha 2-adrenoceptor sites.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Male; Naltrexone; Osmolar Concentration; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Water | 1996 |
Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Conscious Sedation; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Feeding Behavior; Imidazoles; Injections, Intraventricular; Male; Medetomidine; Methoxamine; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
On a dual role for clonidine stimulation of the ventromedial nucleus of the hypothalamus in sodium and potassium renal excretions of rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Hypothalamus; Kidney; Male; Potassium; Prazosin; Rats; Sodium; Yohimbine | 1996 |
Alpha 1-adrenergic receptor antibodies in patients with primary hypertension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Amino Acid Sequence; Animals; Animals, Newborn; Autoantibodies; Blood Proteins; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Heart; Humans; Hypertension; Male; Middle Aged; Molecular Sequence Data; Peptides; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance | 1997 |
Stimulation and blockade of alpha1 adrenoceptors affect behavioural activity, but not spatial working memory assessed by delayed non-matching to position task in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Male; Memory; Prazosin; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha-1 | 1997 |
Modulation of vigilance and behavioral activation by alpha-1 adrenoceptors in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Attention; Behavior, Animal; Clonidine; Male; Prazosin; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha-1 | 1997 |
Heterogeneity and complexity of alpha 1-adrenoceptors in the ovine uterine artery and umbilical vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dioxanes; Drug Interactions; Drug Synergism; Female; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pregnancy; Receptors, Adrenergic, alpha-1; Sheep; Umbilical Veins; Uterus; Vasoconstriction | 1997 |
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1997 |
Involvement of alpha2-adrenoceptors in mediating sympathetic excitation of injured dorsal root ganglion neurons in rats with spinal nerve ligation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Ganglia, Spinal; Ligation; Male; Neurons; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Nerves; Yohimbine | 1997 |
Investigation of alpha1-adrenoceptor subtypes mediating vasoconstriction in rabbit cutaneous resistance arteries.
Topics: Acetonitriles; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Skin; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 1997 |
Characterization of alpha-adrenoceptors in canine mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dogs; Female; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 1997 |
Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Guanfacine; Hallucinogens; Male; Nucleus Accumbens; Phencyclidine; Prazosin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1998 |
A role for amino acid residues in the third cytoplasmic loop in defining the ligand binding characteristics of the alpha2D-adrenergic receptor.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Clonidine; COS Cells; Cytoplasm; Epinephrine; Humans; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxymetazoline; Phentolamine; Prazosin; Protein Binding; Rats; Receptors, Adrenergic, alpha-2; Sequence Alignment; Yohimbine | 1997 |
Stimulation of alpha-1 adrenergic receptors facilitates spatial learning in rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antimetabolites; Clonidine; Cycloserine; Male; Maze Learning; Muscarinic Antagonists; Prazosin; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Scopolamine; Swimming | 1998 |
Characterization of alpha1-adrenoceptor subtypes in facilitation of rat spinal motoneuron activity.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Bridged-Ring Compounds; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Male; Methoxamine; Motor Neurons; Norepinephrine; Oxazines; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Spinal Cord | 1997 |
Drug induced contraction and relaxation in mouse isolated aorta.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Bethanechol; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Potassium Chloride; Prazosin; Serotonin; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 1997 |
Pharmacological and immunocytochemical characterization of subtypes of alpha-1 adrenoceptors in dog aorta.
Topics: Animals; Aorta; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Immunohistochemistry; Indoles; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Spiro Compounds | 1998 |
Presynaptic inhibition by noradrenaline of the EPSC evoked in neonatal rat sympathetic preganglionic neurons.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Animals, Newborn; Clonidine; Excitatory Postsynaptic Potentials; Glutamic Acid; Norepinephrine; Organ Culture Techniques; Oxymetazoline; Patch-Clamp Techniques; Phenylephrine; Prazosin; Presynaptic Terminals; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord | 1998 |
Post- and presynaptic effects of norepinephrine in guinea-pig colonic submucous plexus.
Topics: Acetylcholine; Animals; Clonidine; Colon; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Microelectrodes; Muscle, Smooth; Myenteric Plexus; Neurons; Norepinephrine; Phentolamine; Prazosin; Synapses; Yohimbine | 1998 |
Alpha1-adrenergic stimulation of sarcolemmal Na+-H+ exchanger activity in rat ventricular myocytes: evidence for selective mediation by the alpha1A-adrenoceptor subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Dioxanes; Heart Ventricles; Humans; Imidazoles; Kinetics; Myocardium; Phenylephrine; Piperazines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sarcolemma; Sodium-Hydrogen Exchangers; Tetrahydronaphthalenes | 1998 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Autonomic nervous control of venous pressure and secretion in submandibular gland of anesthetized dogs.
Topics: Acetylcholine; Anesthesia, General; Animals; Arteries; Autonomic Nervous System; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Isoproterenol; Jugular Veins; Male; Parasympathetic Nervous System; Phenobarbital; Phentolamine; Phenylephrine; Prazosin; Propranolol; Pulse; Regional Blood Flow; Saliva; Submandibular Gland; Vasoactive Intestinal Peptide; Veins; Yohimbine | 1998 |
Discrimination of alpha1-adrenoceptor subtypes in rat aorta and prostate.
Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vasoconstriction; Vasodilator Agents | 1998 |
Infarct size-reducing effect of heat stress and alpha1 adrenoceptors in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Heat Stress Disorders; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Infarction; Male; Myocardial Ischemia; Organ Culture Techniques; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reperfusion Injury | 1998 |
Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonidine; Drug Interactions; Lidocaine; Male; Mice; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-2; Seizures; Time Factors; Yohimbine | 1999 |
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Azepines; Binding, Competitive; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Nicergoline; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sensitivity and Specificity; Tritium | 1999 |
Characterization of alpha1-adrenoceptor subtypes mediating vasoconstriction in human umbilical vein.
Topics: Adrenergic Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Umbilical Veins; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Functional characterization of alpha1-adrenoceptor subtypes in longitudinal and circular muscle of human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Alkylating Agents; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Piperazines; Prazosin; Receptors, Adrenergic; Spiperone; Vas Deferens | 1999 |
Alpha 2-adrenoreceptor subtypes regulate ACTH and beta-endorphin secretions during stress in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Clonidine; Dioxanes; Ether; Kinetics; Male; Methoxamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Stress, Physiological | 1999 |
Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Carotid Arteries; Clonidine; Dihydroergotamine; Dogs; Ergotamine; Female; Hemodynamics; Male; Methysergide; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 1999 |
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine | 1998 |
Acute intracranial hypertension-induced inhibition of gastric emptying: evaluation in conscious rats.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Antihypertensive Agents; Antipsychotic Agents; Bretylium Compounds; Carbachol; Cisapride; Clonidine; Consciousness; Female; Gastric Emptying; Gastrointestinal Agents; Intracranial Hypertension; Intracranial Pressure; Male; Ondansetron; Prazosin; Rats; Rats, Wistar; Reference Values; Stomach | 1999 |
Clonidine evokes vasodepressor responses via alpha2-adrenergic receptors in gigantocellular reticular formation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Idazoxan; Male; Medulla Oblongata; Microinjections; Neurons; Prazosin; Rats; Rats, Sprague-Dawley; Reticular Formation | 1999 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Analysis of alpha 1L-adrenoceptor pharmacology in rat small mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cresols; Imidazoles; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Norepinephrine; Piperazines; Potassium; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tetrahydronaphthalenes | 1999 |
Stimulatory effect of beta-adrenergic agonists on ileal L cell secretion and modulation by alpha-adrenergic activation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Epinephrine; Glucagon; Glucagon-Like Peptide 1; Isoproterenol; Peptide Fragments; Peptide YY; Phenylephrine; Prazosin; Protein Precursors; Rats; Rats, Wistar | 1999 |
Evaluation of alpha1-adrenoceptors in the rabbit iris: pharmacological characterization and expression of mRNA.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Gene Expression; In Vitro Techniques; Indoles; Iris; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
Alpha2-adrenergic effect on human breast cancer MCF-7 cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Breast Neoplasms; Cell Division; Cells, Cultured; Clonidine; Cyclic AMP; Epinephrine; Female; Humans; Norepinephrine; Phentolamine; Prazosin; Propranolol; Tumor Cells, Cultured; Yohimbine | 1999 |
Effects of some imidazolidine alpha2-adrenoceptor agonists in rat isolated atria.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Electric Stimulation; Female; Heart Atria; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Muscle Contraction; Norepinephrine; Pargyline; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 1999 |
Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicles | 1999 |
Central benzodiazepine involvement in clonidine cardiovascular actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Carbolines; Cardiovascular Agents; Clonidine; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Heart Rate; Infusions, Intravenous; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Stereotaxic Techniques; Time Factors; Yohimbine | 1999 |
Characterisation of alpha1B-adrenoceptors linked to inositol phosphate formation and calcium mobilisation in human astrocytoma U373 MG cells.
Topics: Adrenergic alpha-Antagonists; Astrocytoma; Calcium; Cell Membrane; Clonidine; Dihydropyridines; Dioxanes; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Thymidine; Tumor Cells, Cultured | 1999 |
The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzofurans; Biogenic Monoamines; Clonidine; Disease Models, Animal; Drug Combinations; Drug Synergism; Locomotion; Male; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Prazosin; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reserpine; Yohimbine | 1999 |
Differences in the electrophysiologic response of four canine ventricular cell types to alpha 1-adrenergic agonists.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Endocardium; Heart Ventricles; In Vitro Techniques; Methoxamine; Microelectrodes; Pericardium; Phenylephrine; Prazosin; Propranolol; Purkinje Fibers | 1999 |
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine | 2000 |
New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; CHO Cells; Clonidine; Cricetinae; Humans; Male; Prazosin; Pyridines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Xylazine; Yohimbine | 2000 |
Methoxamine inhibits transient outward potassium current through alpha1A-adrenoceptors in rat ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Methoxamine; Patch-Clamp Techniques; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Time Factors | 2000 |
Effects of the I(1) imidazoline/alpha(2)-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Benzofurans; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imidazoles; Imidazoline Receptors; Injections, Subcutaneous; Male; Pain; Pain Measurement; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors; Yohimbine | 2000 |
Synthesis and alpha-adrenergic binding ligand affinities of 2-iminoimidazolidine derivatives.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Idazoxan; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Spectrophotometry, Infrared; Yohimbine | 2000 |
NaCl-induced hypertensive rat model of non-insulin-dependent diabetes: role of sympathetic modulation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heart Rate; Hypertension; Injections, Intravenous; Male; Prazosin; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sodium, Dietary; Streptozocin; Sympathetic Nervous System | 2000 |
Participation of alpha-1 and alpha-2 adrenoceptors of the lateral hypothalamic area in water intake, and renal sodium, potassium and urinary volume excretion induced by central administration of angiotensin II.
Topics: Angiotensin II; Animals; Clonidine; Drinking; Drug Administration Schedule; Drug Interactions; Hypothalamic Area, Lateral; Injections, Intraventricular; Kidney; Male; Neural Pathways; Neurons; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sodium; Subfornical Organ; Yohimbine | 2000 |
Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anxiety; Atropine; Clonidine; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Yohimbine | 2000 |
Role of alpha1A-adrenoceptor in the regulation of glucose uptake into white adipocyte of rats in vitro.
Topics: Adipocytes; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Biological Transport, Active; Chromones; Clonidine; Deoxyglucose; Dioxanes; Enzyme Inhibitors; Estrenes; Glucose; Glucose Transporter Type 4; Indoles; Male; Maleimides; Methoxamine; Monosaccharide Transport Proteins; Morpholines; Muscle Proteins; Phenanthridines; Phosphoinositide-3 Kinase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2000 |
Modulation of MK-801-induced behaviour by noradrenergic agents in mice.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Ataxia; Benzylamines; Clonidine; Desipramine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Male; Mesencephalon; Mice; Morpholines; Motor Activity; Norepinephrine; Prazosin; Reboxetine; Stereotyped Behavior | 2001 |
Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cell Membrane; Clonidine; Conserved Sequence; Cricetinae; Dihydropyridines; Dioxanes; Humans; Imidazoles; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Phenylalanine; Piperazines; Prazosin; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship | 2001 |
The noradrenaline-dopamine interaction in the rat medial prefrontal cortex studied by multi-probe microdialysis.
Topics: Adrenergic beta-Antagonists; Animals; Carbachol; Clonidine; Dialysis Solutions; Dopamine; Dopamine Uptake Inhibitors; Functional Laterality; Kainic Acid; Locus Coeruleus; Male; Microdialysis; N-Methylaspartate; Nomifensine; Norepinephrine; Nucleus Accumbens; Prazosin; Prefrontal Cortex; Propranolol; Rats; Rats, Wistar; Time Factors | 2001 |
Functional characterization of alpha(1)-adrenoceptor subtypes in human skeletal muscle resistance arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Arteries; Clonidine; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Muscle, Skeletal; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vasoconstriction | 2001 |
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 2001 |
An isobolographic analysis of the adrenergic modulation of diclofenac antinociception.
Topics: Adrenergic Agents; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Mice; Phenylephrine; Prazosin; Yohimbine | 2001 |
Characterization of alpha1-adrenoceptor-mediated contraction in the mouse thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Buspirone; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Male; Methoxamine; Mice; Models, Biological; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Statistics as Topic; Vasoconstriction | 2001 |
Effect of repeated treatment with tianeptine and fluoxetine on the central alpha(1)-adrenergic system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aggression; Animals; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Clonidine; Exploratory Behavior; Fluoxetine; Hyperkinesis; Male; Methoxamine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Thiazepines | 2001 |
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alveolar Process; Animals; Arteries; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mandible; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction; Xylazine; Yohimbine | 2001 |
Interaction between the antinociceptive effect of ketoprofen and adrenergic modulatory systems.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Injections, Intraperitoneal; Ketoprofen; Mice; Phenylephrine; Prazosin | 2001 |
Norepinephrine induces apoptosis in skin melanophores by attenuating cAMP-PKA signals via alpha2-adrenoceptors in the medaka, Oryzias latipes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apoptosis; Clonidine; Colforsin; Culture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Isoquinolines; Melanophores; Norepinephrine; Oligopeptides; Oryzias; Phenylephrine; Prazosin; Protein Isoforms; Receptors, Adrenergic, alpha-2; Signal Transduction; Skin; Skin Pigmentation; Sulfonamides; Yohimbine | 2001 |
Direct actions of adrenergic agents on rat anterior pituitary cells.
Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Animals; Calcium; Cells, Cultured; Clonidine; Colforsin; Corticotropin-Releasing Hormone; Culture Media; Epinephrine; Follicle Stimulating Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Isoproterenol; Luteinizing Hormone; Male; Phenylephrine; Pituitary Gland, Anterior; Prazosin; Prolactin; Propranolol; Rats; Thyrotropin | 2001 |
Modulatory role of a constitutively active population of alpha(1D)-adrenoceptors in conductance arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Arteries; Calcium; Clonidine; Dose-Response Relationship, Drug; Female; Iliac Artery; Mesenteric Arteries; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance | 2002 |
Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imipramine; Injections, Intraventricular; Male; Nociceptors; Pain; Pain Measurement; Prazosin; Rats; Rats, Wistar; Yohimbine | 2002 |
Inhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Neural Inhibition; Neurons; Prazosin; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Synapses; Synaptic Transmission; Yohimbine | 2002 |
Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Boron Compounds; Clonidine; COS Cells; Flow Cytometry; Fluorescent Dyes; Indoles; Ligands; Microscopy, Confocal; Prazosin; Receptors, Adrenergic, alpha-1; Subcellular Fractions; Transfection | 2002 |
Alpha2 -adrenoceptor function in arterial hypertension associated with obesity in dogs fed a high-fat diet.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Platelets; Blood Pressure; Catecholamines; Clonidine; Diastole; Dietary Fats; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Obesity; Prazosin; Receptors, Adrenergic, alpha; Systole; Yohimbine | 2002 |
Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Signaling; Cell Line; Clonidine; Colforsin; Diazoxide; Enzyme Inhibitors; Epinephrine; Fluorescent Dyes; Fura-2; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Patch-Clamp Techniques; Potassium Channels; Prazosin; Receptors, Adrenergic, alpha-2; Thapsigargin; Tolbutamide | 2002 |
Adrenergic activation of cardiac phospholipase D: role of alpha(1)-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Clonidine; Dioxanes; Male; Myocardium; Norepinephrine; Perfusion; Phospholipase D; Piperazines; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Stimulation, Chemical | 2002 |
Prior iontophoresis of saline enhances vasoconstriction to phenylephrine and clonidine in the skin of the human forearm.
Topics: Administration, Cutaneous; Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Female; Forearm; Humans; Iontophoresis; Male; Phenylephrine; Prazosin; Skin; Sodium Chloride; Vasoconstriction; Yohimbine | 2002 |
Noradrenaline-induced contraction of human saphenous vein and human internal mammary artery: involvement of different alpha-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Aged; Clonidine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Regression Analysis; Saphenous Vein; Yohimbine | 2002 |
Adrenoceptors of the medial septal area modulate water intake and renal excretory function induced by central administration of angiotensin II.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Clonidine; Drinking; Injections, Intraventricular; Kidney; Male; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Septum of Brain; Sodium; Urine; Yohimbine | 2002 |
The role of alpha-adrenoceptors in the amnestic effect of intracerebroventricular dexamethasone.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amnesia; Animals; Avoidance Learning; Clonidine; Dexamethasone; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Memory; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 2002 |
Characterisation of bradykinin B1 and B2 receptors using rat isolated vas deferens.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Prazosin; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Time Factors; Vas Deferens | 2003 |
Mediation of contraction in rat cauda epididymidis by alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epididymis; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine | 2002 |
Influence of prazosin and clonidine on morphine analgesia, tolerance and withdrawal in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Pain; Prazosin; Substance Withdrawal Syndrome; Weight Loss | 2003 |
Cannabinoid-induced Fos expression within A10 dopaminergic neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cannabinoids; Cerebral Cortex; Clonidine; Cyclohexanols; Dopamine; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Limbic System; Locus Coeruleus; Male; Mice; Mice, Inbred ICR; Neurons; Norepinephrine; Prazosin; Receptors, Cannabinoid; Receptors, Drug; Synaptic Transmission | 2003 |
An antihypokinesic action of alpha2-adrenoceptors upon MPTP-induced behaviour deficits in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clonidine; Dopamine; Dopamine Agonists; Drug Interactions; Drug Therapy, Combination; Guanfacine; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Parkinsonian Disorders; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Yohimbine | 2003 |
Yohimbine reverses the exhaustion of the coital reflex in spinal male rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Copulation; Ejaculation; Electromyography; Evoked Potentials; Male; Physical Stimulation; Prazosin; Rats; Rats, Wistar; Reaction Time; Spinal Cord; Spinal Cord Injuries; Yohimbine | 2003 |
Adrenoceptor mechanisms underlying imipramine-induced memory deficits in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Electroshock; Hippocampus; Imipramine; Male; Memory; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Role of specific adrenergic receptors in mediating the adrenocorticotropic hormone response to increased nitric oxide levels.
Topics: Adrenal Glands; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Clonidine; Dobutamine; Hypothalamus; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Norepinephrine; Phenylephrine; Pituitary Gland; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic | 2003 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Norepinephrine; Prazosin; Propranolol; Psychomotor Agitation; Rats; Rats, Wistar | 2003 |
Effects of castration and of testosterone replacement on alpha(1)-adrenoceptor subtypes in the rat vas deferens.
Topics: Animals; Castration; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Neuronal Plasticity; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Testosterone; Time Factors; Vas Deferens; Yohimbine | 2003 |
Regulation of the release of serotonin in the dorsal raphe nucleus by alpha1 and alpha2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Imidazoles; Indoles; Isoindoles; Male; Neurons; Pons; Prazosin; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin | 2003 |
Effects of imipramine on the expression and development of morphine dependence in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Effect of clonidine on colonic motility in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Colon; Drug Interactions; Gastrointestinal Motility; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Time Factors; Yohimbine | 2003 |
Clonidine-induced coronary vasodilatation in isolated guinea pig heart is not mediated by endothelial alpha2 adrenoceptors.
Topics: Animals; Clonidine; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Guinea Pigs; Heart; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phentolamine; Prazosin; Ranitidine; Receptors, Adrenergic, alpha-2; Receptors, Histamine H2; Vasoconstriction; Vasodilation; Yohimbine | 2003 |
Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Autoradiography; Avoidance Learning; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Hippocampus; Iodocyanopindolol; Male; Maze Learning; Memory Disorders; Methoxyhydroxyphenylglycol; Norepinephrine; Phobic Disorders; Prazosin; Radioligand Assay; Rats; Rats, Inbred F344; Space Perception | 2004 |
Tail arteries from chronically spinalized rats have potentiated responses to nerve stimulation in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Autonomic Dysreflexia; Chronic Disease; Clonidine; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Phenylephrine; Potassium; Prazosin; Rats; Rats, Wistar; Spinal Cord Injuries; Tail; Vasoconstriction | 2004 |
Alpha1-adrenoceptor subtypes involved in vasoconstrictor responses to exogenous and neurally released noradrenaline in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; In Vitro Techniques; Male; Muscle, Skeletal; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Hypertension and insulin resistance are not directly related in obese dogs.
Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System | 2004 |
Evidence that alpha(1B)-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Animals; Arteries; Clonidine; Dioxins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Pyrimidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tail | 2004 |
Enhanced arteriolar alpha-adrenergic constriction impairs dilator responses and skeletal muscle perfusion in obese Zucker rats.
Topics: Adrenergic alpha-Agonists; Animals; Arterioles; Clonidine; Male; Metabolic Syndrome; Muscle, Skeletal; Obesity; Phenylephrine; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasoconstrictor Agents; Vasodilation | 2004 |
Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiloride; Animals; Biological Transport; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Norepinephrine; Octopamine; Ouabain; Phenylephrine; Prazosin; Propranolol; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Up-Regulation; Water-Electrolyte Balance; Yohimbine | 2004 |
Submandibular gland acinar cells express multiple alpha1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Membrane; Cells, Cultured; Clonidine; Male; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; RNA, Messenger; Submandibular Gland; Tritium | 2004 |
Pharmacological characterization of alpha1-adrenoceptors in mouse isolated femoral small arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Clonidine induces rat aorta relaxation by nitric oxide-dependent and -independent mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Indomethacin; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Phenylephrine; Potassium Chloride; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasodilation | 2004 |
Role of alpha and beta adrenoceptors in locus coeruleus stimulation-induced reduction in rapid eye movement sleep in freely moving rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Clonidine; Electric Stimulation; Electroencephalography; Electromyography; Electrooculography; Locus Coeruleus; Male; Models, Biological; Picrotoxin; Prazosin; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep, REM; Time Factors; Wakefulness; Yohimbine | 2005 |
Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanfacine; Imidazoles; Injections; Male; Medetomidine; Neural Inhibition; Piperazines; Prazosin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Reflex, Startle; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Yohimbine | 2005 |
Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Mapping; Clonidine; Cocaine; Cognition Disorders; Discrimination Learning; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Macaca mulatta; Male; Membrane Proteins; Memory; Nerve Tissue Proteins; Neuropsychological Tests; Prazosin; Prefrontal Cortex; Radioligand Assay; Receptors, Catecholamine; Statistics as Topic; Tritium | 2005 |
Fentanyl attenuates alpha1B-adrenoceptor-mediated pulmonary artery contraction.
Topics: Anesthetics, Intravenous; Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Fentanyl; Hydrogen-Ion Concentration; In Vitro Techniques; Phenylephrine; Piperazines; Prazosin; Pulmonary Artery; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2005 |
Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amides; Animals; Arteries; Clonidine; Electric Stimulation; Electrophysiology; Female; Idazoxan; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Phenylephrine; Prazosin; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Suramin; Tail; Vasoconstriction | 2005 |
Characterisation of alpha2-adrenoceptor subtypes involved in gastric emptying, gastric motility and gastric mucosal defence.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Yohimbine | 2005 |
Plasticity of brain alpha-adrenoceptors during the development of diet-induced obesity in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Fatty Acids; Male; Obesity; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Synaptosomes | 1994 |
Activation of subfornical organ neurons in rats through pre- and postsynaptic alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Clonidine; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Neurons; Norepinephrine; Patch-Clamp Techniques; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Presynaptic; Sodium-Calcium Exchanger; Subfornical Organ; Tetrodotoxin | 2006 |
Role of noradrenergic and GABA-ergic inputs in pedunculopontine tegmentum for regulation of rapid eye movement sleep in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Choline O-Acetyltransferase; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Male; Mesencephalon; Microinjections; Norepinephrine; Picrotoxin; Polysomnography; Pons; Prazosin; Propranolol; Rats; Rats, Wistar; Sleep, REM; Wakefulness | 2006 |
Acute lead exposure and contraction of rat isolated aorta induced by D1-dopaminergic and alpha-adrenergic drugs.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Aorta; Benzazepines; Cardiotonic Agents; Clonidine; Dopamine; Dose-Response Relationship, Drug; Lead; Male; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Wistar; Yohimbine | 2006 |
Alpha1L-adrenoceptors mediate contractions of the isolated mouse prostate.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Dopamine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Indoles; Isoproterenol; Male; Mice; Muscle Contraction; Norepinephrine; Phenylephrine; Prazosin; Prostate; Receptors, Adrenergic, alpha-1; Yohimbine | 2006 |
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes.
Topics: Acetyl-CoA C-Acyltransferase; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiperone; Suramin; Sympathetic Nervous System; Synaptic Transmission; Testis | 2006 |
The contribution of alpha-1 and alpha-2 adrenoceptors in peripheral imidazoline and adrenoceptor agonist-induced nociception.
Topics: Adrenergic alpha-Agonists; Agmatine; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoline Receptors; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cocaine; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2006 |
Alpha1A-adrenergic receptors are functionally expressed by a subpopulation of cornu ammonis 1 interneurons in rat hippocampus.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; In Vitro Techniques; Interneurons; Isoproterenol; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2007 |
Adrenergic control of a constitutively active acetylcholine-regulated potassium current in canine atrial cardiomyocytes.
Topics: Acetylcholine; Action Potentials; Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bee Venoms; Clonidine; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Estrenes; Heart Atria; Imidazoles; Indoles; Isoproterenol; Isoquinolines; Maleimides; Myocytes, Cardiac; Patch-Clamp Techniques; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Potassium Channels; Prazosin; Propanolamines; Propranolol; Protein Kinase C; Pyrrolidinones; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Sulfonamides; Type C Phospholipases | 2007 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Pharmacologic reduction of CNS noradrenergic activity in PTSD: the case for clonidine and prazosin.
Topics: Adrenergic alpha-Antagonists; Adult; Arousal; Brain; Clonidine; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Dreams; Female; Humans; Male; Middle Aged; Norepinephrine; Practice Guidelines as Topic; Prazosin; Stress Disorders, Post-Traumatic; Sympatholytics | 2007 |
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Extinction, Psychological; Fluoxetine; Flupenthixol; Grooming; Hydrocortisone; Injections, Intravenous; Norepinephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-2; Saimiri; Saliva; Self Administration; Thiophenes | 2007 |
Pre- and postsynaptic mechanisms in the clonidine- and oxymetazoline-induced inhibition of gastric motility in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Insulin; Isoindoles; Male; Muscarinic Agonists; Muscle Contraction; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Receptors, Presynaptic; Stomach; Synapses | 2007 |
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Terbutaline; Vas Deferens; Vasodilation; Xylazine; Yohimbine | 2008 |
alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Burns; Clonidine; Female; Hot Temperature; Humans; Hyperalgesia; Iontophoresis; Male; Nociceptors; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Sensory Receptor Cells; Skin; Yohimbine; Young Adult | 2009 |
Potentiation by yohimbine of alpha-adrenoceptor-mediated vasoconstriction in response to clonidine in the rabbit ear vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Ear; Imidazoles; Male; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Vasoconstrictor Agents; Veins; Yohimbine | 2008 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2009 |
Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anesthesia, Local; Anesthetics, Local; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Methoxamine; Nifedipine; Nitroglycerin; Pain Measurement; Phentolamine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2009 |
Effects of acute exposure of alpha 1- and alpha 2-adrenoreceptor agonist or antagonist on capsaicin-evoked substance P release from dorsal root ganglion neurons in vitro.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Capsaicin; Cells, Cultured; Clonidine; Ganglia, Spinal; Neurons; Phenylephrine; Prazosin; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Yohimbine | 2010 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment | 2011 |
Effects of prazosin, clonidine, and propranolol on the elevations in brain reward thresholds and somatic signs associated with nicotine withdrawal in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prazosin; Propranolol; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2010 |
Best practice guide for the treatment of nightmare disorder in adults.
Topics: Adult; Clonidine; Cognitive Behavioral Therapy; Dreams; Evidence-Based Medicine; Eye Movement Desensitization Reprocessing; Humans; Hypnosis; Norepinephrine; Prazosin; Psychotropic Drugs; Randomized Controlled Trials as Topic; Relaxation Therapy; Stress Disorders, Post-Traumatic | 2010 |
Sympathetic vasoconstriction is potentiated in arteries caudal but not rostral to a spinal cord transection in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Data Interpretation, Statistical; Electric Stimulation; Female; Muscle Contraction; Myography; Phenylephrine; Potassium Chloride; Prazosin; Purinergic P2 Receptor Antagonists; Purinergic P2X Receptor Agonists; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Stimulation, Chemical; Suramin; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Endothelin modulates the cardiovascular effects of clonidine in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Gas Analysis; Blood Pressure; Brain; Clonidine; Endothelins; Heart Rate; Male; Oligopeptides; Peptide Fragments; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Vasoconstriction | 2010 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Adrenergic receptors modulate motoneuron excitability, sensory synaptic transmission and muscle spasms after chronic spinal cord injury.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Chromones; Clonidine; Excitatory Postsynaptic Potentials; Female; Idazoxan; Models, Animal; Motor Neurons; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Sensory Receptor Cells; Spasm; Spinal Cord Injuries; Synaptic Transmission | 2011 |
The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder.
Topics: Acoustic Stimulation; Aggression; Animals; Brain Mapping; Clonidine; Disease Models, Animal; Electric Stimulation; Humans; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Prazosin; Reflex, Startle; Social Behavior; Stress Disorders, Post-Traumatic; Stress, Psychological | 2011 |
Adrenergic control of vascular resistance varies in muscles composed of different fiber types: influence of the vascular endothelium.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Fibers; Analysis of Variance; Animals; Arterioles; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Hindlimb; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscle, Smooth, Vascular; Oxidation-Reduction; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sympathectomy; Vascular Resistance; Vasoconstriction | 2011 |
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Guanfacine; Imidazoles; Imidazoline Receptors; Isoquinolines; Male; Motor Activity; Naphthyridines; Prazosin; Propranolol; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2011 |
Sensitization in relation to posttraumatic stress disorder.
Topics: Acoustic Stimulation; Animals; Brain; Clonidine; Disease Models, Animal; Mice; Norepinephrine; Prazosin; Reflex, Startle; Stress Disorders, Post-Traumatic | 2011 |
Molecular and pharmacological characteristics of the gerbil α(1a)-adrenergic receptor.
Topics: Adrenergic alpha-1 Receptor Antagonists; Amino Acid Sequence; Animals; Arteries; Chlorocebus aethiops; Clonidine; Cloning, Molecular; Cochlea; Conserved Sequence; COS Cells; Dioxanes; Dose-Response Relationship, Drug; Gerbillinae; Humans; Mice; Molecular Sequence Data; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Sequence Analysis, Protein; Transfection; Vasoconstriction | 2012 |
Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; Benzenesulfonates; Clonidine; Electrodes, Implanted; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prazosin; Quinolines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reward; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2012 |
Ma huang and alpha subtype adrenoceptors in the cat pulmonary vascular bed.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ephedra sinica; Female; Lung; Male; Phentolamine; Piperazines; Prazosin; Prospective Studies; Pulmonary Circulation; Receptors, Adrenergic; Vasoconstrictor Agents | 2008 |
The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Idazoxan; Male; Methoxamine; Movement; Neurons; Norepinephrine; Nucleus Accumbens; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2012 |
Chronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesia.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Clonidine; Drug-Seeking Behavior; Heroin; Heroin Dependence; Hyperalgesia; Narcotics; Prazosin; Propranolol; Pyrimidines; Rats; Receptors, Corticotropin-Releasing Hormone; Self Administration | 2015 |
Hippocampal α-adrenoceptors involve in the effect of histamine on spatial learning.
Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; CA1 Region, Hippocampal; Clonidine; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Male; Maze Learning; Phenylephrine; Prazosin; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Task Performance and Analysis; Yohimbine | 2014 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |
Norepinephrine responses in rat renal and femoral veins are reinforced by vasoconstrictor prostanoids.
Topics: Animals; Clonidine; Endothelium, Vascular; Femoral Vein; Kidney; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2015 |
Memory of a drug lapse: Role of noradrenaline.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Animals; Basolateral Nuclear Complex; Clonidine; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Heroin; Locus Coeruleus; Male; Memory; Narcotics; Norepinephrine; Prazosin; Propranolol; Rats, Sprague-Dawley; Spatial Behavior; Substance-Related Disorders | 2015 |
Adrenergic ligands that block oviposition in the cattle tick Rhipicephalus microplus affect ovary contraction.
Topics: Acaricides; Adrenergic Agents; Albuterol; Animals; Cattle; Clonidine; Dibenzazepines; Female; Imidazoles; Isoproterenol; Octopamine; Ovary; Oviposition; Prazosin; Rhipicephalus; Tissue Culture Techniques; Toluidines; Tyramine; Video Recording | 2015 |
Medical Approach to the Management of Traumatized Refugees.
Topics: Adult; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Clonidine; Depression; Dreams; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prazosin; Psychotherapy; Refugees; Stress Disorders, Post-Traumatic | 2016 |
Activation of alpha-1 adrenergic receptors increases cytosolic calcium in neurones of the paraventricular nucleus of the hypothalamus.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Benzophenanthridines; Cadmium Chloride; Calcium; Clonidine; Cytosol; Estrenes; Macrocyclic Compounds; Male; Neurons; Norepinephrine; Oxazoles; Paraventricular Hypothalamic Nucleus; Phenylephrine; Prazosin; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha-1; Thapsigargin | 2019 |