clonidine and piperoxan

clonidine has been researched along with piperoxan in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	63 (90.00)	18.7374
1990's	7 (10.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
England, CD; Smith, CF; Stillings, MR; Welbourn, AP	1
Andrews, PR; Craik, DJ; Martin, JL	1
Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF	1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B	1
Timmermans, PB; van Zwieten, PA	1
Kapur, H; Mottram, DR	1
Bentley, GA; Brazenor, RM	1
Baraban, JM; Davis, M; Redmond, DE	1
Aghajanian, GK; Bunney, BS	1
Franklin, KB; Herberg, LJ	1
Dausse, J; Meyer, P; Miach, PJ	1
Fang, VS; Fessler, RG; Meltzer, HY	1
Donabedian, RK; Gold, MS; Redmond, DE	2
Kapur, H; Rouot, B; Snyder, SH	1
Innemee, HC; van Zwieten, PA	2
Aghajanian, GK; Cedarbaum, JM	1
Aghajanian, GK; Cedarbaum, JM; Davis, M; Gendelman, DS	1
Hattox, SE; Landis, DH; Maas, JW; Roth, RH	1
Keil, LC; Nolan, PL; Reid, IA; Wolf, JA	1
Buus Lassen, J	1
Franklin, KB	1
Halliday, CA; Jones, BJ; Skingle, M; Tyers, MB; Walsh, DM; Wise, H	1
Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Monassier, L; Tibiriça, E	1
Fukuda, H; Mishima, A; Ono, H; Ono, S; Vasko, MR	1
Fukuda, H; Ono, H; Tanabe, M	1
Hadjiconstantinou, M; Krajnc, D; Neff, NH; Rossetti, Z	1
De Sarro, A; De Sarro, GB	1
Paul, SM; Wolkowitz, OM	1
Colpaert, FC; Janssen, PA	1
Labatut, R; Lecestre, D; Milne, B; Pujol, JF; Quintin, L; Richard, F	1
Marwah, J; Pitts, DK	1
Ambrose, MJ; Hoffman, LJ; Simson, PG; Weiss, JM	1
Huchet, AM; Huguet, F; Legrand, M; Narcisse, G; Tsoucaris-Kupfer, D	1
Kassarich, J; Lien, EL; Morrison, A; Sullivan, D	1
Simson, PG; Weiss, JM	1
Laubie, M; Schmitt, H	1
Haigler, HJ; O'Neill, TP	1
Starke, K; Tanaka, T	1
Humphrey, SJ; McCall, RB	1
Nolan, PL; Reid, IA	1
Aghajanian, GK; Andrade, R	2
Blakeley, AG; Cunnane, TC; Petersen, SA	1
Clapham, JC; Hamilton, TC	1
Kobinger, W	1
Batink, HD; Timmermans, PB; van Kemenade, JE; van Zwieten, PA	1
Alkondon, M; Ray, A; Sen, P; Sharma, KK	1
Iuvone, PM; Rauch, AL	1
Gaillard, JM	1
Nomura, Y; Oki, K; Segawa, T	1
Baumann, PA; Koella, WP	1
Sybertz, EJ; Zimmerman, BG	1
McLennan, PL	1
Aghajanian, GK; VanderMaelen, CP	1
Aghajanian, GK	1
Bhargava, KP; Gurtu, S; Sinha, JN	1
Dedek, J; Scatton, B; Zivkovic, B	1
Gaillard, JM; Justafre, JC; Kafi, S	1
Blakeley, AG; Cunnane, TC; Maskell, T; Mathie, A; Petersen, SA	1
Geyer, MA; Lee, EH	1
Buda, M; De Simoni, G; Gonon, F; Pujol, JF	1
Cervo, L; Rochat, C; Romandini, S; Samanin, R	1
D'Mello, GD	1
Bentley, GA; McLennan, PL	1
Elsworth, JD; Redmond, DE; Roth, RH	1
Blackwell, CP; Johnson, MA; Smith, J	1
Dunn, RW; La Marca, S	1
Colpaert, F; Marien, M; Tellez, S	1

Reviews

2 review(s) available for clonidine and piperoxan

Article	Year
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs. Journal of medicinal chemistry, 1982, Volume: 25, Issue:12 Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses	1982
Neural and molecular mechanisms in anxiety. The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1 Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Carbolines; Clonidine; Disease Models, Animal; Forecasting; Haplorhini; Humans; Locus Coeruleus; Piperoxan; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Research Design; Yohimbine	1985

Article

Year

alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.

Journal of medicinal chemistry, 1982, Volume: 25, Issue:12

Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses

1982

Neural and molecular mechanisms in anxiety.

The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Carbolines; Clonidine; Disease Models, Animal; Forecasting; Haplorhini; Humans; Locus Coeruleus; Piperoxan; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Research Design; Yohimbine

1985

Trials

1 trial(s) available for clonidine and piperoxan

Article	Year
Antagonism of the effects of clonidine by the alpha 2-adrenoceptor antagonist, fluparoxan. British journal of clinical pharmacology, 1995, Volume: 39, Issue:5 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Blood Pressure; Bradycardia; Clonidine; Cross-Over Studies; Double-Blind Method; Growth Hormone; Heart Rate; Humans; Hypotension; Infusions, Intravenous; Male; Piperoxan; Psychomotor Performance; Pyrroles; Xerostomia	1995

Article

Year

Antagonism of the effects of clonidine by the alpha 2-adrenoceptor antagonist, fluparoxan.

British journal of clinical pharmacology, 1995, Volume: 39, Issue:5

Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Blood Pressure; Bradycardia; Clonidine; Cross-Over Studies; Double-Blind Method; Growth Hormone; Heart Rate; Humans; Hypotension; Infusions, Intravenous; Male; Piperoxan; Psychomotor Performance; Pyrroles; Xerostomia

1995

Other Studies

67 other study(ies) available for clonidine and piperoxan

Article	Year
Effect of methoxy substitution on the adrenergic activity of three structurally related alpha 2-adrenoreceptor antagonists. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Adrenergic alpha-Antagonists; Animals; Chemical Phenomena; Chemistry; Clonidine; Dioxanes; Dioxins; Imidazoles; Male; Mice; Muscle Contraction; Phenylephrine; Piperidines; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship	1986
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants. Journal of medicinal chemistry, 1983, Volume: 26, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens	1983
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction	1984
A comparative study on the pre- and post-synaptic alpha blocking activity of a series of benzodioxanes. Biochemical pharmacology, 1978, Volume: 27, Issue:14 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Piperidines; Piperoxan; Rats; Synapses; Yohimbine	1978
Effects of alpha-agonists on circulatory responses to somatic afferent nerve stimulation. European journal of pharmacology, 1978, Oct-15, Volume: 51, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Electric Stimulation; Female; Heart Rate; Hemodynamics; Hemorrhage; Male; Neurons, Afferent; Norepinephrine; Piperoxan; Reflex	1978
Noradrenergic agonists and antagonists: effects on conditioned fear as measured by the potentiated startle paradigm. Psychopharmacology, 1979, Volume: 65, Issue:2 Topics: Animals; Clonidine; Conditioning, Operant; Fear; Male; Norepinephrine; Piperoxan; Propranolol; Rats; Reflex, Startle; Yohimbine	1979
Dopamine"autoreceptors": pharmacological characterization by microiontophoretic single cell recording studies. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1 Topics: Action Potentials; Animals; Apomorphine; Catecholamines; Clonidine; Dextroamphetamine; Feedback; Iontophoresis; Male; Piperoxan; Rats; Receptors, Dopamine; Sotalol; Substantia Nigra; Synaptic Transmission; Trifluoperazine	1977
Presynaptic alpha-adenoceptors: the depression of self-stimulation by clonidine and its restoration by piperoxane but not by phentolamine or phenoxybenzamine. European journal of pharmacology, 1977, May-01, Volume: 43, Issue:1 Topics: Animals; Clonidine; Drug Interactions; Male; Phenoxybenzamine; Phentolamine; Piperidines; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Self Stimulation; Stereotaxic Techniques; Synapses	1977
Direct biochemical demonstration of two types of alpha-adrenoreceptor in rat brain. Nature, 1978, Aug-03, Volume: 274, Issue:5670 Topics: Animals; Binding, Competitive; Brain; Clonidine; Dihydroergotoxine; Dopamine; Male; Phenoxybenzamine; Phentolamine; Piperoxan; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptic Membranes; Yohimbine	1978
Effect of piperoxane on rat plasma prolactin. Communications in psychopharmacology, 1978, Volume: 2, Issue:3 Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Male; Piperidines; Piperoxan; Prolactin; Rats; Receptors, Adrenergic, alpha	1978
Clonidine-induced increase in serum growth hormone: possible role of epinephrine-mediated synapses. Psychoneuroendocrinology, 1978, Volume: 3, Issue:2 Topics: Animals; Brain; Clonidine; Epinephrine; Growth Hormone; Haplorhini; Macaca; Piperoxan; Receptors, Adrenergic, alpha; Synapses	1978
Effect of piperoxane on serum prolactin: possible role of epinephrine-mediated synapses in the inhibition of prolactin secretion. Endocrinology, 1978, Volume: 102, Issue:4 Topics: Animals; Clonidine; Epinephrine; Haplorhini; Male; Piperidines; Piperoxan; Prolactin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses	1978
Binding to alpha-adrenergic receptors: differential pharmacological potencies and binding affinities of benzodioxanes. European journal of pharmacology, 1979, Aug-15, Volume: 57, Issue:4 Topics: Animals; Cerebral Cortex; Clonidine; Hydroxydopamines; Male; Muscle Contraction; Norepinephrine; Piperidines; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptosomes	1979
An increase in intraocular pressure due to clonidine. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1978, Aug-16, Volume: 207, Issue:3 Topics: Animals; Blood Pressure; Carotid Arteries; Cats; Clonidine; Female; Gallamine Triethiodide; Injections, Intravenous; Intraocular Pressure; Male; Piperoxan; Rats; Tubocurarine	1978
The central ocular hypotensive effect of clonidine. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Apr-02, Volume: 210, Issue:2 Topics: Animals; Blood Pressure; Cats; Clonidine; Dose-Response Relationship, Drug; Eye; Female; Infusions, Intra-Arterial; Intraocular Pressure; Male; Piperoxan; Vertebral Artery	1979
Catecholamine receptors on locus coeruleus neurons: pharmacological characterization. European journal of pharmacology, 1977, Aug-15, Volume: 44, Issue:4 Topics: Action Potentials; Animals; Apomorphine; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Iontophoresis; Isoproterenol; Male; Neurons; Nordefrin; Norepinephrine; Phenylephrine; Piperoxan; Rats; Receptors, Adrenergic; Sotalol; Trifluoperazine	1977
Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats. Psychopharmacology, 1977, Mar-16, Volume: 51, Issue:3 Topics: Acoustic Stimulation; Animals; Cerebral Ventricles; Clonidine; Decerebrate State; Drug Interactions; Habituation, Psychophysiologic; Male; Phentolamine; Piperoxan; Rats; Reflex, Startle; Time Factors	1977
A direct method for studying 3-methoxy-4-hydroxyphenethyleneglycol (MHPG) production by brain in awake animals. European journal of pharmacology, 1977, Dec-01, Volume: 46, Issue:3 Topics: Animals; Brain; Clonidine; Glycols; Haplorhini; Macaca; Methods; Methoxyhydroxyphenylglycol; Piperoxan; Time Factors	1977
Suppression of vasopressin secretion by clonidine: effect of alpha-adrenoceptor antagonists. Endocrinology, 1979, Volume: 104, Issue:5 Topics: Animals; Blood Pressure; Clonidine; Dogs; Female; Heart Rate; Male; Phentolamine; Piperidines; Piperoxan; Vasopressins	1979
Piperoxane reduces the effects of clonidine on aggression in mice and on noradrenaline dependent hypermotility in rats. European journal of pharmacology, 1978, Jan-01, Volume: 47, Issue:1 Topics: Aggression; Animals; Clonidine; Drug Antagonism; Female; Humans; Male; Mice; Motor Activity; Norepinephrine; Piperidines; Piperoxan; Rats; Tyramine	1978
Catecholamines and self-stimulation: reward and performances effects dissociated. Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:6 Topics: Animals; Catecholamines; Clonidine; Dopamine; Electrodes, Implanted; Male; Motor Activity; Norepinephrine; Pimozide; Piperoxan; Rats; Reward; Self Stimulation	1978
The pharmacology of fluparoxan: a selective alpha 2-adrenoceptor antagonist. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Aorta; Body Temperature; Brimonidine Tartrate; Clonidine; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Piperoxan; Postural Balance; Pyrroles; Quinoxalines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Histamine; Receptors, Muscarinic; Receptors, Serotonin; Vas Deferens	1991
Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Catecholamines; Clonidine; Dioxanes; Electrochemistry; Hemodynamics; Idazoxan; Imidazoline Receptors; Male; Medulla Oblongata; Neurons; Oxazoles; Piperoxan; Rats; Rats, Inbred WKY; Receptors, Drug; Reticular Formation; Rilmenidine; Stereotaxic Techniques; Yohimbine	1991
Inhibitory effects of clonidine and tizanidine on release of substance P from slices of rat spinal cord and antagonism by alpha-adrenergic receptor antagonists. Neuropharmacology, 1991, Volume: 30, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Parasympatholytics; Piperoxan; Prazosin; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Veratridine; Yohimbine	1991
Spinal alpha 1- and alpha 2-adrenoceptors mediate facilitation and inhibition of spinal motor transmission, respectively. Japanese journal of pharmacology, 1990, Volume: 54, Issue:1 Topics: Animals; Clonidine; Clorgyline; Levodopa; Male; Motor Neurons; Piperoxan; Prazosin; Premedication; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission	1990
Modulation of retinal aromatic L-amino acid decarboxylase via alpha 2 adrenoceptors. Journal of neurochemistry, 1989, Volume: 52, Issue:2 Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Clonidine; Cycloheximide; Darkness; Dihydroxyphenylalanine; Kinetics; Light; Male; Oxymetazoline; Phentolamine; Piperoxan; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Retina; Yohimbine	1989
Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice. Neuropharmacology, 1989, Volume: 28, Issue:3 Topics: Adenosine; Adrenergic alpha-Antagonists; Aminophylline; Animals; Anticonvulsants; Clonidine; Habituation, Psychophysiologic; Methysergide; Mice; Mice, Inbred DBA; Piperoxan; Yohimbine	1989
Discriminative stimulus properties of xylazine in rat: discriminability and effects of putative alpha-2 adrenoceptor agonists and antagonists. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Discrimination Learning; Idazoxan; Lisuride; Lysergic Acid Diethylamide; Male; Piperoxan; Rats; Rats, Inbred Strains; Thiazines; Xylazine; Yohimbine	1985
Long-term effects of RU24722 on tyrosine hydroxylase of the rat brain. Journal of neurochemistry, 1988, Volume: 51, Issue:5 Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Locus Coeruleus; Male; Neurons; Piperoxan; Rats; Rats, Inbred Strains; Substantia Nigra; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase; Vinca Alkaloids; Vincamine	1988
Effects of cocaine on the electrical activity of single noradrenergic neurons from locus coeruleus. Life sciences, 1986, Mar-31, Volume: 38, Issue:13 Topics: Animals; Clonidine; Cocaine; Electrophysiology; Locus Coeruleus; Male; Neurons; Norepinephrine; Piperoxan; Procaine; Rats; Receptors, Adrenergic, alpha	1986
Reversal of behavioral depression by infusion of an alpha-2 adrenergic agonist into the locus coeruleus. Neuropharmacology, 1986, Volume: 25, Issue:4 Topics: Animals; Clonidine; Depression; Electroshock; Locus Coeruleus; Male; Piperoxan; Rats; Receptors, Adrenergic, alpha; Swimming	1986
Interaction between central alpha 1- and alpha 2-adrenoceptors on sympathetic tone in rats. Neuropharmacology, 1986, Volume: 25, Issue:5 Topics: Animals; Azepines; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Injections, Intraventricular; Male; Phenylacetates; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vagotomy	1986
Alpha-2-adrenergic control of prolactin release. Neuroendocrinology, 1986, Volume: 44, Issue:2 Topics: Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Male; Piperoxan; Pregnancy; Prolactin; Quinolizines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1986
Depression in an animal model: focus on the locus ceruleus. Ciba Foundation symposium, 1986, Volume: 123 Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Clonidine; Depression; Electroshock; Locus Coeruleus; Norepinephrine; Pargyline; Piperoxan; Receptors, Adrenergic, alpha; Stress, Physiological	1986
Prazosin produces a sustained and reflex-mediated increase in renal sympathetic nerve activity in anesthetized dogs. European journal of pharmacology, 1988, Jun-22, Volume: 151, Issue:1 Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Female; Heart Rate; Infusions, Intra-Arterial; Kidney; Male; Neurons; Piperoxan; Prazosin; Pressoreceptors; Reflex; Sympathetic Nervous System; Vertebral Artery	1988
Effects of clonidine on neuronal firing evoked by a noxious stimulus. Brain research, 1985, Feb-18, Volume: 327, Issue:1-2 Topics: Animals; Clonidine; Electrophysiology; Isoquinolines; Male; Neurons; Norepinephrine; Pain; Physical Stimulation; Piperazines; Piperoxan; Rats; Rats, Inbred Strains; Stimulation, Chemical; Yohimbine	1985
Antagonist/agonist-preferring alpha-adrenoceptors or alpha 1/alpha 2-adrenoceptors? European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; In Vitro Techniques; Male; Piperoxan; Pulmonary Artery; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine	1980
Evidence for a central depressor action of postsynaptic alpha 1-adrenergic receptor antagonists. Journal of the autonomic nervous system, 1981, Volume: 3, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Depression, Chemical; Dioxanes; Hemodynamics; Phentolamine; Piperoxan; Prazosin; Pressoreceptors; Receptors, Adrenergic; Sympathetic Nervous System	1981
Inhibition of renin secretion by clonidine after alpha-adrenoceptor blockade in anesthetized dogs. Clinical and experimental hypertension, 1981, Volume: 3, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dogs; Female; Heart Rate; Male; Phentolamine; Piperoxan; Renin	1981
Single cell activity in the noradrenergic A-5 region: responses to drugs and peripheral manipulations of blood pressure. Brain research, 1982, Jun-17, Volume: 242, Issue:1 Topics: Amphetamine; Animals; Blood Pressure; Clonidine; Electric Stimulation; Male; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Piperoxan; Rats; Tegmentum Mesencephali	1982
Local regulation of transmitter release from rodent sympathetic nerve terminals? The Journal of physiology, 1982, Volume: 325 Topics: Animals; Clonidine; Feedback; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscle, Smooth; Neuroeffector Junction; Neurotransmitter Agents; Piperoxan; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens	1982
Involvement of presynaptic dopamine receptors in the antihypertensive response to 2-NN-dimethylamino-5,6-dihydroxy-1,2,3,4,-tetrahydronaphthalene (M-7). The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:10 Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Injections, Intraventricular; Male; Naphthols; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sympathetic Nervous System	1982
Central blood pressure regulation. Involvement of presynaptic or postsynaptic, alpha 1- or alpha 2-adrenoceptors? Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Cats; Clonidine; Dogs; Heart Rate; Medulla Oblongata; Oxymetazoline; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses	1983
Selectivity of benzodioxane alpha-adrenoceptor antagonists for alpha 1- and alpha 2-adrenoceptors determined by binding affinity. Pharmacology, 1983, Volume: 26, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Clonidine; In Vitro Techniques; Male; Membranes; Piperidines; Piperoxan; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1983
Modulation of footshock aggression in rats by clonidine: involvement of both alpha 1- and alpha 2-adrenoceptors. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:9 Topics: Aggression; Animals; Clonidine; Humans; Male; Phenoxybenzamine; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1983
Alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons. Life sciences, 1983, Dec-12, Volume: 33, Issue:24 Topics: Adaptation, Physiological; Animals; Cerebellum; Clonidine; Darkness; Dopamine; Male; Neurons; Photic Stimulation; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Retina; Tyrosine 3-Monooxygenase; Yohimbine	1983
Biochemical pharmacology of paradoxical sleep. British journal of clinical pharmacology, 1983, Volume: 16 Suppl 2 Topics: alpha-Methyltyrosine; Animals; Chlorpromazine; Clonidine; Humans; Hydroxydopamines; Locus Coeruleus; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Methyltyrosines; Norepinephrine; Oxidopamine; Piperoxan; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Serotonin; Sleep, REM; Synaptic Transmission; Tyrosine 3-Monooxygenase; Yohimbine	1983
Pharmacological characterization of central alpha-adrenoceptors which mediate clonidine-induced locomotor hypoactivity in the developing rat. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 311, Issue:1 Topics: Aging; Animals; Central Nervous System; Clonidine; Female; Male; Motor Activity; Phentolamine; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors; Yohimbine	1980
Feedback control of noradrenaline release as a function of noradrenaline concentration in the synaptic cleft in cortical slices of the rat. Brain research, 1980, May-12, Volume: 189, Issue:2 Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Feedback; Male; Neural Inhibition; Norepinephrine; Piperoxan; Rats; Receptors, Adrenergic, alpha; Synapses	1980
The role of alpha receptors in the facilitation of the chemoreflex and inhibition of the carotid occlusion reflex by clonidine. Clinical and experimental hypertension, 1980, Volume: 2, Issue:6 Topics: Animals; Blood Pressure; Carotid Arteries; Carotid Body; Clonidine; Dogs; Female; Male; Phentolamine; Piperoxan; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine	1980
The hypothermic effect of clonidine and other imidazolidines in relation to their ability to enter the central nervous system in mice. European journal of pharmacology, 1981, Feb-19, Volume: 69, Issue:4 Topics: Animals; Blood-Brain Barrier; Body Temperature; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Hypothermia; Imidazoles; Mice; Piperoxan; Receptors, Adrenergic, alpha	1981
alpha 2-adrenoceptor-mediated hyperpolarization of locus coeruleus neurons: intracellular studies in vivo. Science (New York, N.Y.), 1982, Mar-12, Volume: 215, Issue:4538 Topics: Animals; Clonidine; Locus Coeruleus; Male; Membrane Potentials; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Transmission	1982
Central noradrenergic neurons: a locus for the functional interplay between alpha-2 adrenoceptors and opiate receptors. The Journal of clinical psychiatry, 1982, Volume: 43, Issue:6 Pt 2 Topics: Animals; Clonidine; Dendrites; Evoked Potentials; Humans; Locus Coeruleus; Morphine; Neural Inhibition; Neurons; Norepinephrine; Piperoxan; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Synapses; Synaptic Transmission	1982
Involvement of alpha2-adrenoceptors of nucleus tractus solitarius in baroreflex mediated bradycardia. Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:1 Topics: Animals; Blood Pressure; Cats; Cisterna Magna; Clonidine; Female; Guanethidine; Heart Rate; Injections; Male; Medulla Oblongata; Microinjections; Piperoxan; Pressoreceptors; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex	1982
Lack of involvement of alpha 2-adrenoceptors in the regulation of striatal dopaminergic transmission. European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4 Topics: Acetylcholine; Animals; Clonidine; Corpus Striatum; Dioxins; Dopamine; Idazoxan; Male; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Yohimbine	1983
On the role of brain alpha-adrenergic systems in the production of paradoxical sleep. L'Encephale, 1982, Volume: 8, Issue:3 Topics: Animals; Chlorpromazine; Clonidine; Desipramine; Male; Phenoxybenzamine; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Secologanin Tryptamine Alkaloids; Sleep, REM	1982
Locus coeruleus activity in vitro: intrinsic regulation by a calcium-dependent potassium conductance but not alpha 2-adrenoceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:1 Topics: Action Potentials; Animals; Calcium; Clonidine; Electric Conductivity; Locus Coeruleus; Male; Neurons; Ouabain; Piperoxan; Potassium; Pterins; Rats; Receptors, Adrenergic, alpha; Tyrosine	1984
Alpha-adrenoceptors and facilitation at a sympathetic neuroeffector junction. Journal of autonomic pharmacology, 1984, Volume: 4, Issue:1 Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscle, Smooth; Neural Conduction; Neuroeffector Junction; Piperoxan; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine	1984
Effects of clonidine, piperoxane and locus coeruleus lesion on the serotonergic and dopaminergic systems in raphe and caudate nucleus. Biochemical pharmacology, 1984, Nov-01, Volume: 33, Issue:21 Topics: Animals; Caudate Nucleus; Clonidine; Dopamine; Hydroxydopamines; Locus Coeruleus; Male; Oxidopamine; Piperidines; Piperoxan; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin	1984
Catecholamine metabolism in the rat locus coeruleus as studied by in vivo differential pulse voltammetry. II. Pharmacological and behavioral study. Brain research, 1983, Aug-29, Volume: 273, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Clonidine; Desipramine; Haloperidol; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Piperoxan; Rats; Reserpine; Stress, Physiological	1983
Evidence of a preferential role of brain serotonin in the mechanisms leading to naloxone-precipitated compulsive jumping in morphine-dependent rats. Psychopharmacology, 1981, Volume: 74, Issue:3 Topics: Animals; Behavior, Animal; Brain; Clonidine; Humans; Male; Morphine Dependence; Naloxone; Piperoxan; Piribedil; Rats; Serotonin; Substance Withdrawal Syndrome; Sympatholytics	1981
Comparison of the discriminative stimulus properties of clonidine and amphetamine in rats. Neuropharmacology, 1982, Volume: 21, Issue:8 Topics: Amphetamine; Animals; Clonidine; Cues; Discrimination, Psychological; Extinction, Psychological; Male; Phenoxybenzamine; Piperoxan; Rats	1982
Effects of prazosin and piperoxan on central cardiovascular actions of St 91 in cats. European journal of pharmacology, 1982, Dec-17, Volume: 86, Issue:1 Topics: Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Piperidines; Piperoxan; Prazosin; Quinazolines; Vertebral Artery	1982
Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates. Brain research, 1982, Mar-04, Volume: 235, Issue:1 Topics: Animals; Brain; Brain Chemistry; Chlorocebus aethiops; Clonidine; Drug Interactions; Glycols; Methoxyhydroxyphenylglycol; Morphine; Naloxone; Norepinephrine; Piperoxan	1982
The alpha-2 antagonists idazoxan and rauwolscine but not yohimbine or piperoxan are anxiolytic in the Vogel lick-shock conflict paradigm following intravenous administration. Life sciences, 1994, Volume: 54, Issue:10 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clonidine; Conflict, Psychological; Dioxanes; Drinking Behavior; GABA Antagonists; Idazoxan; Infusions, Intravenous; Male; Piperoxan; Rats; Rats, Sprague-Dawley; Yohimbine	1994
Acetylcholine release in the rat prefrontal cortex in vivo: modulation by alpha 2-adrenoceptor agonists and antagonists. Journal of neurochemistry, 1997, Volume: 68, Issue:2 Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Guanabenz; Idazoxan; Imidazoles; Male; Microdialysis; Piperoxan; Prefrontal Cortex; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley	1997