clonidine has been researched along with phencyclidine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Carlsson, M; Svensson, A | 1 |
| Pezzola, A; Popoli, P; Scotti de Carolis, A | 1 |
| McCann, DJ; Rabin, RA; Winter, JC | 1 |
| Benishin, CG; Cooper, JR; Pearce, LB | 1 |
| Leander, JD | 1 |
| Hescheler, J; Krautwurst, D; Musgrave, IF; Schultz, G | 1 |
| Elsworth, JD; Jentsch, JD; Redmond, DE; Roth, RH; Taylor, JR | 1 |
| Jentsch, JD; Katz, Z; Roth, RH; Wise, A | 1 |
| Anzivino, LA; Jentsch, JD | 1 |
| Avedian, T; Jentsch, JD; Kuperman, J; Marrs, W; Roth, RH | 1 |
| Elsworth, JD; Jentsch, JD; Roth, RH; Sanchez, D | 1 |
16 other study(ies) available for clonidine and phencyclidine
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice.
Topics: Animals; Atropine; Clonidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; N-Methylaspartate; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate | 1990 |
An EEG and behavioural study on the interactions of clonidine with phencyclidine and ketamine in rats.
Topics: Animals; Brain; Clonidine; Drug Interactions; Electroencephalography; Ketamine; Male; Muscle Tonus; Phencyclidine; Prazosin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1990 |
Interactions of clonidine with phencyclidine and ketamine: studies of radial maze performance and righting reflex in rats.
Topics: Anesthesia; Animals; Behavior, Animal; Clonidine; Drug Interactions; Ketamine; Learning; Male; Phencyclidine; Rats; Rats, Inbred F344; Reflex | 1987 |
Isolation of a factor (substance B) that antagonizes presynaptic modulation: pharmacological properties.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain Chemistry; Clonidine; Guinea Pigs; Hexamethonium Compounds; Ileum; Morphine; Muscle Contraction; Oxotremorine; Phencyclidine; Phenylisopropyladenosine; Synaptosomes | 1986 |
A kappa opioid effect: increased urination in the rat.
Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Diuretics; Ethylketocyclazocine; Male; Narcotic Antagonists; Narcotics; Phencyclidine; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1983 |
Clonidine and cirazoline inhibit activation of nicotinic channels in PC-12 cells.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Calcium; Clonidine; Imidazoles; Ion Channels; Nicotinic Antagonists; PC12 Cells; Phencyclidine; Radioligand Assay; Rats; Receptors, Nicotinic; Torpedo; Tritium | 1995 |
Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia.
Topics: Animals; Clonidine; Dopamine; Frontal Lobe; Functional Laterality; Haplorhini; Humans; Neurons; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Receptors, Adrenergic, alpha-2; Schizophrenia | 1998 |
Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Guanfacine; Hallucinogens; Male; Nucleus Accumbens; Phencyclidine; Prazosin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1998 |
A low dose of the alpha2 agonist clonidine ameliorates the visual attention and spatial working memory deficits produced by phencyclidine administration to rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Attention; Clonidine; Dose-Response Relationship, Drug; Male; Memory Disorders; Phencyclidine; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Visual Perception | 2004 |
Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Benzylamines; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanfacine; Imidazoles; Male; Memory Disorders; Memory, Short-Term; Neurotransmitter Uptake Inhibitors; Phencyclidine; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Sex Factors; Spatial Behavior | 2005 |
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Disease Models, Animal; Dopamine; Guanfacine; Imidazoles; Isoindoles; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Schizophrenia | 2008 |