clonidine and pentobarbital

clonidine has been researched along with pentobarbital in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199027 (64.29)18.7374
1990's6 (14.29)18.2507
2000's7 (16.67)29.6817
2010's2 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dinnendahl, V; Gumulka, SW1
De Jong, W; Zandberg, P1
Bloch, R; Bousquet, P; Feldman, J; Gaertner, M1
Bravkov, MF1
Trolin, GG1
Loh, HH; Tseng, LF; Wei, ET1
Waldeck, B1
Trolin, G1
Cerutti, C; Koenig-Bérard, E; Sannajust, F; Sassard, J1
Holtzman, SG1
Abe, K; Imai, Y; Minami, N; Munakata, M; Nihei, M; Sasaki, S; Sekino, H; Yoshinaga, K1
Dinovo, EC; Haddox, VG; Menon, MK1
Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K1
Pichler, L; Stumpf, C1
Ham, IW; Heslop, KE; Mathias, CJ; May, CN; Stone, FA1
Deguchi, Y; Hanada, S; Kaneto, H1
Kodama, CK; Menon, MK1
Dollery, CT; Lewis, PJ; Reid, JL1
Gomes, C; Henning, M; Persson, B; Trolin, G1
Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG; Scatton, B1
Jurna, I1
Decobert, M; Depoortere, H; Honoré, L1
Emmett-Oglesby, MW; Lal, H; Lewis, MW; Spencer, DG1
Advenier, C; Floch, A; Mallard, B1
Kuhn, CM; Schanberg, SM1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Clough, DP; Hatton, R; Pettinger, SJ1
Gerhardt, S; Liebman, JM1
Maixner, W; Watkins, L1
Aantaa, R; Scheinin, M1
Hanin, I; Wülfert, E; Zhang, X1
Dohi, S; Iida, H; Ishiyama, T1
Farber, NB; Kim, SH; Olney, JW; Price, MT1
Dohi, S; Iida, H; Iida, M; Takenaka, M1
Hamdard, F; Hussain, AS; Mayhew, JF; Siddiqui, MS1
Honda, K; Inomata, S; Misawa, S; Nagashima, A; Tanaka, E1
Cechinel-Filho, V; Gurgel, LA; Lima-Júnior, RC; Martins, DT; Rao, VS; Santos, FA1

Reviews

3 review(s) available for clonidine and pentobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug effects on the EEG of various species of laboratory animals.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine

1983
Alpha 2-adrenergic agents in anaesthesia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:5

    Topics: Analgesics; Anesthetics; Animals; Clonidine; Humans; Imidazoles; Medetomidine; Pentobarbital; Rabbits; Rats; Receptors, Adrenergic, alpha

1993

Other Studies

39 other study(ies) available for clonidine and pentobarbital

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Stress-induced alterations of cyclic nucleotide levels in brain: effects of centrally acting drugs.
    Psychopharmacology, 1977, May-09, Volume: 52, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Chlorpromazine; Clonidine; Cyclic AMP; Cyclic GMP; Diazepam; Diphenhydramine; Haloperidol; Indomethacin; Male; Mice; Pentobarbital; Phentolamine; Propanolamines; Propranolol; Reserpine; Stress, Physiological

1977
Hypotensive action of clonidine after adrenalectomy in the rat.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:11

    Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Clonidine; Depression, Chemical; Heart Rate; Male; Pentobarbital; Rats; Urethane

1977
[Variations in the effect of clonidine on arterial pressure in rats in the presence of various anesthetics].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:5

    Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Blood Pressure; Chloralose; Clonidine; Ketamine; Male; Pentobarbital; Progesterone; Rats; Urethane

1977
[Effect of hypotensive agents on baroreceptor reflexes in waking animals].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 87, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Heart Rate; Methyldopa; Pentobarbital; Pressoreceptors; Reflex; Reserpine

1979
Involvement of alpha-adrenergic receptors at different levels of the central nervous system in the regulation of blood pressure and heart frequency.
    Acta physiologica Scandinavica. Supplementum, 1975, Volume: 430

    Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Dopamine; Heart Rate; Hydroxydopamines; Levodopa; Nerve Degeneration; Neurons; Norepinephrine; Pentobarbital; Rats; Receptors, Adrenergic; Serotonin

1975
Effects of clonidine on morphine withdrawal signs in the rat.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Anesthesia; Animals; Body Temperature; Cerebral Ventricles; Clonidine; Escape Reaction; Exophthalmos; Humans; Injections; Male; Morphine Dependence; Naloxone; Norepinephrine; Pentobarbital; Piloerection; Rats; Substance Withdrawal Syndrome; Time Factors; Tremor

1975
On the interaction between caffeine and barbiturates with respect to locomotor activity and brain catecholamines.
    Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:2

    Topics: Animals; Brain; Caffeine; Clonidine; Dopamine; Drug Interactions; Female; Mice; Motor Activity; Norepinephrine; Pentobarbital; Phenobarbital; Piribedil; Reserpine

1975
Effects of pentobarbitone and decerebration on the clonidine-induced circulatory changes.
    European journal of pharmacology, 1975, Volume: 34, Issue:1

    Topics: Animals; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hemodynamics; Male; Pentobarbital; Rats; Time Factors

1975
Influence of anaesthesia on the cardiovascular effects of rilmenidine and clonidine in spontaneously hypertensive rats.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Male; Oxazoles; Pentobarbital; Rats; Rats, Inbred SHR; Reflex; Rilmenidine; Sympathetic Nervous System

1992
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline

1986
Modulation of cardiovascular depressant action of clonidine by pentobarbital anesthesia in rats.
    The Tohoku journal of experimental medicine, 1989, Volume: 157, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Pentobarbital; Pulse; Rats; Time Factors

1989
Modification of certain pharmacological effects of ethanol by lipophilic alpha-1 adrenergic agonists.
    Life sciences, 1987, Sep-28, Volume: 41, Issue:13

    Topics: Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Drug Interactions; Ethanol; Hypnosis; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Pentobarbital; Tetrahydronaphthalenes

1987
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 2

    Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine

1988
Synchronizing effect of the alpha 1-adrenoceptor agonist 2-(2-chloro-5-trifluoromethylphenylimino)imidazolidine on rabbit electroencephalogram.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Animals; Blood Pressure; Clonidine; Electrocardiography; Electroencephalography; Female; Heart Rate; Male; Pentobarbital; Prazosin; Rabbits

1988
Intravenous morphine causes hypertension, hyperglycaemia and increases sympatho-adrenal outflow in conscious rabbits.
    Clinical science (London, England : 1979), 1988, Volume: 75, Issue:1

    Topics: Animals; Blood; Blood Glucose; Blood Pressure; Catecholamines; Clonidine; Heart Rate; Histamine Antagonists; Infusions, Intravenous; Male; Morphine; Osmolar Concentration; Pentobarbital; Phenoxybenzamine; Potassium; Rabbits

1988
Diversity of underlying mechanisms in the production of analgesic and pentobarbital-hypnosis prolonging effects of various analgesic drugs and stresses.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:1

    Topics: Analgesics; Animals; Clonidine; Electroshock; Hypnotics and Sedatives; Immersion; Male; Mice; Naloxone; Pentobarbital; Stress, Psychological

1985
Further studies on the ethanol antagonism exhibited by 2(2-chloro-5-trifluoromethyl phenylimino) imidazolidine (St 587).
    Life sciences, 1985, Dec-02, Volume: 37, Issue:22

    Topics: Animals; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pentobarbital; Pimozide; Sleep; Time Factors

1985
Central and peripheral mechanisms in the maintenance of experimental hypertension in the rabbit.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:5

    Topics: Anesthesia; Animals; Aorta; Carotid Sinus; Cellophane; Central Nervous System; Cisterna Magna; Clonidine; Denervation; Hypertension; Hypertension, Renal; Injections; Injections, Intravenous; Male; Pentobarbital; Pentolinium Tartrate; Rabbits

1973
Pre- and postsynaptic alpha-adrenoceptor antagonists: differentiated cardiovascular effects in the rat.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Pentobarbital; Phenoxybenzamine; Phentolamine; Prazosin; Premedication; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine

1980
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Clonidine; Dogs; Female; Heart; Heart Rate; Imidazoles; Male; Norepinephrine; Oxymetazoline; Pentobarbital; Quinoxalines; Rats; Spinal Cord; Synapses; Tachycardia; Vagotomy

1982
Pain-depressing agents and the spinal nociceptive system.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:9A

    Topics: Analgesics; Animals; Ceruletide; Clonidine; Diazepam; Endorphins; Humans; Morphine; Motor Neurons; Neurons, Afferent; Nociceptors; Pentobarbital; Receptors, GABA-A; Receptors, Opioid; Reflex; Sincalide; Spinal Cord; Substance P; Synapses

1984
Bioassay of subjective effects associated with benzodiazepine withdrawal in animals: a novel direction in dependence research.
    NIDA research monograph, 1984, Volume: 49

    Topics: Animals; Benzodiazepinones; Biological Assay; Clonidine; Conditioning, Operant; Diazepam; Discrimination Learning; Flumazenil; Generalization, Stimulus; Humans; Male; Pentobarbital; Pentylenetetrazole; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1984
Bronchopulmonary effects of clonidine on the bronchomotor responses of the guinea-pig.
    European journal of pharmacology, 1983, Apr-22, Volume: 89, Issue:1-2

    Topics: Acetylcholine; Airway Resistance; Animals; Atropine; Bronchi; Clonidine; Drug Interactions; Guinea Pigs; Hemodynamics; In Vitro Techniques; Lung; Male; Muscle, Smooth; Pentobarbital; Propranolol; Reserpine; Respiration

1983
Maturation of central nervous system control of growth hormone secretion in rats.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:1

    Topics: 5-Hydroxytryptophan; Aging; Animals; Central Nervous System; Clonidine; Female; Growth Hormone; Male; Morphine; Pentobarbital; Rats

1981
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
A new centrally acting antihypertensive (ICI 106270) which separates antihypertensive effects from sedation.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:10

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Female; Heart Rate; Hypertension, Renal; Imidazoles; Motor Activity; Pentobarbital; Rats; Sleep; Sympathetic Nervous System

1981
Differential effects of drug treatments on nose-poke and bar-press self-stimulation.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:5

    Topics: Animals; Clonidine; Conditioning, Operant; Haloperidol; Male; Methocarbamol; Pentobarbital; Rats; Rats, Inbred F344; Self Stimulation

1981
Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:2

    Topics: Anesthesia; Animals; Autonomic Nerve Block; Blood Pressure; Clonidine; Depression, Chemical; Heart Rate; In Vitro Techniques; Male; Parasympathetic Nervous System; Pentobarbital; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System

1993
Mivazerol, a new alpha 2-adrenergic agonist, blunts cardiovascular effects following surgical stress in pentobarbital-anesthetized rats.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Clonidine; Heart Rate; Imidazoles; Medetomidine; Pentobarbital; Rats; Rats, Sprague-Dawley; Stress, Physiological; Surgical Procedures, Operative; Yohimbine

1997
The vascular effects of topical and intravenous alpha2-adrenoceptor agonist clonidine on canine pial microcirculation.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:4

    Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Blood Glucose; Cerebrovascular Circulation; Clonidine; Craniotomy; Dogs; Dose-Response Relationship, Drug; Glyburide; Heart Rate; Injections, Intravenous; Microcirculation; Pentobarbital; Pia Mater; Potassium; Potassium Channel Blockers; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Vasodilator Agents; Veins; Yohimbine

1998
Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists.
    Molecular psychiatry, 1999, Volume: 4, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Clonidine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ketamine; Microdialysis; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

1999
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
    Anesthesiology, 2000, Volume: 92, Issue:5

    Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Veins; Cerebrovascular Circulation; Clonidine; Dexmedetomidine; Hemodynamics; Hypercapnia; Hypoxia; Injections, Spinal; Pentobarbital; Rabbits; Vasodilation; Yohimbine

2000
Postoperative apnoea in an ex-premature infant: is it only related to clonidine?
    Paediatric anaesthesia, 2003, Volume: 13, Issue:8

    Topics: Analgesics; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Local; Apnea; Bupivacaine; Clonidine; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Male; Pentobarbital; Postoperative Complications

2003
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Animals; Cimetidine; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ketoconazole; Lidocaine; Microsomes, Liver; Midazolam; Neuromuscular Depolarizing Agents; Pentobarbital; Pharmacogenetics; Premedication; Rats; Theophylline; Thiamylal

2005
Dragon's blood from Croton urucurana (Baill.) attenuates visceral nociception in mice.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Abdominal Pain; Acetylcysteine; Administration, Oral; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Capsaicin; Clonidine; Croton; Cyclophosphamide; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Pentobarbital; Plant Extracts; Sleep; Time Factors

2007